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Functioning Pituitary Adenoma malady
2 drugs, 30 genes, 3 tissues, 588 related diseases, 19 phenotypes, 31 articles, clinical trials.

Summaries for Functioning Pituitary Adenoma

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MalaCards: Functioning Pituitary Adenoma, also known as secretory adenoma of the pituitary gland, is related to parathyroid adenoma and colorectal adenoma and carcinoma. An important gene associated with Functioning Pituitary Adenoma is CORT (cortistatin), and among its related pathways are Class A/1 (Rhodopsin-like receptors) and Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q. The drugs octreotide acetate and octreotide and the compounds rc 160 and cyclosomatostatin have been mentioned in the context of this disorder. Affiliated tissues include thyroid, endothelial and pituitary, and related mouse phenotypes are respiratory system and endocrine/exocrine gland.

Aliases & Descriptions for Functioning Pituitary Adenoma

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43UMLS, 6Disease Ontology, 27NCIt
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Aliases & Descriptions:

functioning pituitary adenoma 6
secretory adenoma of the pituitary gland 6
pituitary adenoma, functioning 43
adenoma 43

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NCIt27 C8388

Related Diseases for Functioning Pituitary Adenoma

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13GeneCards, 14GeneDecks
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Diseases related to functioning pituitary adenoma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 585)
idRelated DiseaseScoreTop Affiliating Genes
1parathyroid adenoma33.3PCNA, MKI67, APC, IGF1, GNAS
2colorectal adenoma and carcinoma33.3PCNA, LEP, MKI67, APC
3adrenal adenoma32.9MKI67, APC, POMC, ADM
4cushing's syndrome32.5GH1, SST, POMC
5polyposis31.0PCNA, APC, IGF1, GNRH1, ESR1, SST
6aldosteronism30.8CGA, APC, IGF1, GH1, DRD2, PRL
7sebaceous adenoma29.9MKI67, ESR1
8growth hormone secreting pituitary adenoma29.9CGA, IGF1, GNAS, GH1, GHR, SST
9chromophobe adenoma29.9GH1, PRL
10leydig cell adenoma29.1CGA, GNRH1
11fetal adenoma29.0GH1, SSTR2, SSTR5, CORT, PRL
12tsh producing pituitary tumor28.8GH1, PRL
13meningioma28.6PCNA, MKI67, ESR1
14headache28.4IGF1, DRD2, SST, PRL, ADM
15thyroid carcinoma28.1PCNA, CGA, MKI67, APC, ESR1, STAT5A
16primary hyperparathyroidism27.9LEP, IGF1, GNAS, GH1, SST, PRL
17mccune albright syndrome27.6APC, GNAS, GH1, PRL
18multiple endocrine neoplasia27.4APC, IGF1, GNAS, GNRH1, GH1, SST
19virilization27.4LEP, CGA, GNRH1, POMC
20carney complex27.2GNAS, GH1, PRL, POMC
21papillary thyroid carcinoma27.2PCNA, LEP, MKI67, APC, SST
22goiter27.1LEP, CGA, IGF1, GNAS, GH1, SST
23sinusitis26.8PCNA, CGA, MKI67, IGF1, GH1, PRL
24nelson syndrome26.8SST, PRL, POMC
25insulinoma26.7SCGN, IGF1, GH1, GHR, SST, SSTR1
26cystadenoma26.7PCNA, MKI67, ESR1, SST
27breast cancer26.6APC, ESR1, GHR, PRL
28acromegaly26.6LEP, APC, IGF1, GNAS, GNRH1, GH1
29hyperparathyroidism26.6PCNA, LEP, IGF1, GNAS, GNRH1, GH1
30vipoma26.6GH1, SST, SSTR3
3121-hydroxylase deficiency26.5LEP, GNRH1, GH1, PRL, POMC
32adrenal hyperplasia26.3LEP, CGA, IGF1, GNAS, GNRH1, GH1
33craniopharyngioma26.3PCNA, LEP, CGA, MKI67, IGF1, GH1
34ulcerative colitis26.2PCNA, LEP, MKI67, APC, ESR1, SST
35gigantism26.2IGF1, GNAS, GH1, GHR, HMGA2, SST
36carcinoma26.2PCNA, SCGN, LEP, CGA, MKI67, APC
37growth hormone deficiency26.1LEP, IGF1, GNAS, GNRH1, GH1, GHR
38gastric adenocarcinoma26.0APC, PTPN3, SSTR2, SSTR3
39hyperthyroidism25.9LEP, CGA, IGF1, GNAS, GH1, GHR
40pituitary tumor25.9APC, IGF1, GNAS, GNRH1, ESR1, GH1
41pituitary carcinoma25.9PCNA, SST, SSTR2, PRL, POMC
42colon cancer25.9PCNA, LEP, MKI67, APC, IGF1, ESR1
43adrenocortical hyperplasia25.8APC, GNAS, POMC
44astrocytoma25.6PCNA, MKI67, IGF1, GHR, HMGA2, SST
45retinoblastoma25.4PCNA, MKI67, APC, IGF1, ESR1, HMGA2
46endometrial adenocarcinoma25.3PCNA, MKI67, IGF1, ESR1, POMC
47paraganglioma25.3PCNA, SST, SSTR2, POMC
48adenocarcinoma25.1PCNA, SCGN, LEP, CGA, MKI67, APC
49adenoma25.1PCNA, SCGN, LEP, CGA, MKI67, APC
50pituitary adenoma25.1PCNA, SCGN, LEP, CGA, MKI67, APC

Graphical network of the top 20 diseases related to functioning pituitary adenoma:



Graphical network of diseases related to functioning pituitary adenoma

Clinical Features for Functioning Pituitary Adenoma

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Drugs & Therapeutics for Functioning Pituitary Adenoma

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for functioning pituitary adenoma

Inferred drug relations via UMLS/NDF-RT:

43 28 octreotide, octreotide acetate

Genetic Tests for Functioning Pituitary Adenoma

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Anatomical Context for Functioning Pituitary Adenoma

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22MalaCards
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MalaCards organs/tissues related to functioning pituitary adenoma:

22
Thyroid, Endothelial, Pituitary

Phenotypes for genes affiliated with Functioning Pituitary Adenoma

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25MGI
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MGI Mouse Phenotypes related to functioning pituitary adenoma:

25 (show all 19)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1respiratory system phenotypeMP:000538810.0SSTR4, DRD2
2endocrine/exocrine gland phenotypeMP:00053799.4CORT, HMGA2, GHR, GNRH1, GNAS, GNAI2
3hematopoietic system phenotypeMP:00053979.3GAPDH, SSTR4, GNAI2, APC, PCNA
4liver/biliary system phenotypeMP:00053708.7ADM, PRL, STAT5A, DRD2, GHR, GH1
5limbs/digits/tail phenotypeMP:00053718.3DRD2, HMGA2, GHR, ESR1, GNAS, LEP
6nervous system phenotypeMP:00036317.9POMC, PRL, SSTR2, SSTR1, DRD2, HMGA2
7integument phenotypeMP:00107717.8POMC, PRL, STAT5A, SSTR4, DRD2, HMGA2
8reproductive system phenotypeMP:00053897.8PRL, STAT5A, DRD2, HMGA2, GH1, GNRH1
9no phenotypic analysisMP:00030127.4POMC, SSTR4, SSTR3, SST, PTPN3, DRD2
10skeleton phenotypeMP:00053907.4DRD2, ESR1, GNRH1, GNAS, IGF1, APC
11growth/size phenotypeMP:00053787.2DRD2, PTPN3, SST, SSTR5, CORT, STAT5A
12renal/urinary system phenotypeMP:00053676.9GAPDH, ADM, POMC, DRD2, GHR, ESR1
13adipose tissue phenotypeMP:00053756.8POMC, STAT5A, DRD2, HMGA2, GHR, GH1
14tumorigenesisMP:00020066.5DRD2, STAT5A, PRL, POMC, ESR1, GNRH1
15cardiovascular system phenotypeMP:00053856.4DRD2, SSTR2, POMC, ADM, GAPDH, GHR
16behavior/neurological phenotypeMP:00053865.6SSTR2, SSTR4, RXRG, CORT, STAT5A, PRL
17cellular phenotypeMP:00053845.6ADM, POMC, STAT5A, SSTR1, DRD2, ESR1
18immune system phenotypeMP:00053874.9PTPN3, SST, SSTR4, STAT5A, PRL, POMC
19homeostasis/metabolism phenotypeMP:00053763.9LEP, SSTR1, SSTR2, SSTR4, SSTR5, CORT

Publications for genes affiliated with Functioning Pituitary Adenoma

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35PubMed
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Articles related to functioning pituitary adenoma:

(show all 31)
idTitleAuthorsYearAffiliating Genes
1Co-expression of somatostatin receptor subtypes and e strogen receptor-I+ mRNAs by non-functioning pituitary adenomas in young patient s. (20797424)Nishioka H.... Haraoka J.2011ESR1
2Prevalence of gsp oncogene in somatotropinomas and cl inically non-functioning pituitary adenomas: our experience. (18642089)Taboada G.F.... Gadelha M.R.2009GNAS, GH1
3Non-functioning pituitary adenomas: clinical feature, laboratorial and imaging assessment, therapeutic management and outcome. (19347183)Cury M.L.... Castro M.2009PRL
4GH replacement in patients with non-functioning pituitary adenoma (NFA) treated solely by surgery is not associated with increased risk of tumour recurrence. (19236640)Arnold J.R.... Wass J.A.2009GH1
5Efficacy of a dopamine-somatostatin chimeric molecule, BIM-23A760, in the control of cell growth from primary cultures of human non-functioning pituitary adenomas: a multi-center study. (18509006)Florio T.... Jaquet P.2008SSTR2, SSTR3, SST
6Medical therapy for clinically non-functioning pituitary adenomas. (18780796)Colao A.... Savastano S.2008SST
7Effects of selective somatostatin analogs and cortistatin on cell viability in cultured human non-functioning pituitary adenomas. (18276067)Padova H.... Shimon I.2008SSTR2, SSTR5, SST
8Non-functioning pituitary adenomas infrequently harbor G-protein gene mutations. (19169048)Ruggeri R.M.... CannavA^ S.2008APC, GNAS, GNAI2
9Quantitative analysis of somatostatin receptor subtype (SSTR1-5) gene expression levels in somatotropinomas and non-functioning pituitary adenomas. (17218727)Taboada G.F.... Gadelha M.R.2007SSTR2, SSTR3, SSTR5
10Pasireotide, a multiple somatostatin receptor subtypes ligand, reduces cell viability in non-functioning pituitary adenomas by inhibiting vascular endothelial growth factor secretion. (17395978)Zatelli M.C.... degli Uberti E.C.2007SSTR5, SST
11Clinically non-functioning pituitary adenoma. (17082898)Jaffe C.A.2006SST
12The effect of selective sst1, sst2, sst5 somatostatin receptors agonists, a somatostatin/dopamine (SST/DA) chimera and bromocriptine on the 'clinically non-functioning' pituitary adenomas in vitro. (16115652)Gruszka A.... Pawlikowski M.2006SST
13Non-functioning pituitary adenomas: clinical features and immunohistochemistry (16400431)Ferreira J.E.... Schmitt F.2005POMC
14Characteristics of adult patients with growth hormone deficiency who underwent neurosurgery for functioning and non-functioning pituitary adenomas and craniopharyngiomas. (15887862)Baldelli R.... De Marinis L.2005IGF1
15High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy. (16322327)Pierantoni G.M.... Larizza L.2005HMGA2
16Growth hormone receptor expression and function in pituitary adenomas. (15104560)Clausen L.R.... rgensen J.O.2004IGF1, GHR, STAT5A
17Proteomics and transcriptomics analyses of secretagogin down-regulation in human non-functional pituitary adenomas. (15237930)Zhan X.... Desiderio D.M.2003SCGN
18Genetic heterogeneity and alterations in chromosome 9 loci in a localized region of a functional pituitary adenoma. (11297766)Jotwani G.... Sinha S.2001PRL
19Gene expression of adrenomedullin, leptin, their receptors and neuropeptide Y in hormone-secreting and non-functioning pituitary adenomas, meningiomas and malignant intracranial tumours in humans. (11489141)Knerr I.... Rascher W.2001GAPDH, LEP, ADM
20Hormone levels and tumour size response to quinagolide and cabergoline in patients with prolactin-secreting and clinically non-functioning pituitary adenomas: predictive value of pituitary scintigraphy with 123I-methoxybenzamide. (10762286)Colao A.... Lombardi G.2000DRD2, PRL
21Metamorphosis of a non-functioning pituitary adenoma to Cushing's disease. (11141695)Tan E.U.... Rajasoorya C.R.2000POMC
22Somatostatin and its analog lanreotide inhibit the proliferation of dispersed human non-functioning pituitary adenoma cells in vitro. (10526255)Florio T.... Schettini G.1999SST, PTPN3
23Retinoid X receptor gamma mRNA expression is reduced in recurrent non-functioning pituitary adenomas. (9640424)Gittoes N.J.... Franklyn J.A.1998RXRG
24Glycoprotein hormone alpha-subunit secretion in non-functioning pituitary adenomas (9411334)GA^th M.... SzilA!gyi G.1997CGA
25Somatostatin receptor imaging in somatotroph and non-functioning pituitary adenomas: correlation with hormonal and visual responses to octreotide. (9425399)Broson-Chazot F.... Warnet A.1997SST
26Unique binding pattern to concanavalin A lectin of glycoprotein hormones alpha-subunit hypersecreted by non-functioning pituitary adenomas. (9437241)Asteria C.... Beck-Peccoz P.1997CGA
27The correlation of Ki-67 staining indices with tumour doubling times in regrowing non-functioning pituitary adenomas. (9030353)Ekramullah S.M.... Hayakawa T.1996PCNA, MKI67
28Acute and chronic effects of octreotide on thyroid axis in growth hormone-secreting and clinically non-functioning pituitary adenomas. (7655643)Colao A.... Lombardi G.1995SST, GH1
29Effects of long-term treatment with the gonadotropin-releasing hormone analog nafarelin in patients with non-functioning pituitary adenomas. (8162161)Colombo P.... Faglia G.1994GNRH1
30Octreotide treatment does not affect the size of most non-functioning pituitary adenomas. (8227984)Gasperi M.... Martino E.1993SST
31Analgesic effect on headaches of octreotide, a somatostatin analogue, in a case of non-functioning pituitary adenoma (1838161)Turpin G.... de Gennes J.L.1991SST

Expression for genes affiliated with Functioning Pituitary Adenoma

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Functioning Pituitary Adenoma

Pathways for genes affiliated with Functioning Pituitary Adenoma

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38Reactome, 10EMD Millipore, 20KEGG, 36QIAGEN
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Pathways related to functioning pituitary adenoma according to GeneDecks:

idPathwayScoreTop Affiliating Genes
1Class A/1 (Rhodopsin-like receptors)389.8SSTR5, SSTR4, SSTR3, SSTR2, SSTR1
2Neuropeptides signaling through G-protein alpha-i & G-protein alpha-q109.7SSTR5, SSTR4, SSTR3, SSTR2, SSTR1, GNAI2
3Gastric acid secretion209.6SSTR2, SST, GNAS, GNAI2
4Growth Hormone Signaling369.3STAT5A, GHR, GH1, IGF1
5Jak-STAT signaling pathway208.8LEP, GH1, GHR, STAT5A, PRL
6eNOS Signaling368.3IGF1, GNAI2, GNRH1, ESR1, GH1
7JAK-STAT Pathway367.9PRL, STAT5A, GHR, GH1, GNRH1, IGF1
8Neuroactive ligand-receptor interaction207.9LEP, PRL, SSTR5, SSTR4, SSTR3, SSTR2

Compounds for genes affiliated with Functioning Pituitary Adenoma

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42Tocris Bioscience, 18HMDB, 32Novoseek , 9DrugBank, 34PharmGKB
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Compounds related to functioning pituitary adenoma according to GeneDecks:

(show top 50)    (show all 177)
idCompoundScoreTop Affiliating Genes
1rc 16042 10.1SSTR1, SSTR2, SSTR3, SSTR4, SSTR5
2cyclosomatostatin42 10.1SSTR4, SSTR3, SSTR1, SSTR5
3somatostatin42 18 11.0SSTR3, SSTR4, SSTR5, SSTR1, SSTR2
4sodium nitroprusside32 9.6PCNA, CGA, SST, GAPDH
5glucose32 9.4CORT, SSTR2, GAPDH, SSTR1, APC, MKI67
6quinagolide32 9.0IGF1, PRL, SST, DRD2, GH1
7bromocriptine32 9 9 11.0POMC, PRL, SST, GH1, GNRH1
8ghrp32 8.9GHR, IGF1, PRL, SST, GH1
9epinephrine32 9 18 9 11.8LEP, CGA, APC, GNRH1, DRD2, POMC
10metoclopramide32 9 9 10.8PRL, CGA, DRD2, GH1, GNRH1
11cetrorelix32 9 9 10.7PCNA, LEP, CGA, IGF1, GNRH1
12buserelin32 9 9 10.7CGA, GNRH1, PRL, IGF1, SST
13naltrexone32 34 9 9 11.6PRL, POMC, GNRH1, GH1
14hexarelin32 8.4IGF1, GH1, CORT, PRL, POMC, SST
15gnrh32 8.3GH1, IGF1, MKI67, LEP, GNAS, POMC
16dopamine32 9 18 9 11.3GNRH1, GNAS, APC, CGA, GH1, DRD2
17lanreotide32 8.2IGF1, GH1, GHR, PTPN3, SST, SSTR1
18letrozole32 42 9 9 11.2LEP, CGA, MKI67, IGF1, ESR1
19cabergoline32 9 9 10.1CGA, IGF1, GNRH1, GH1, GHR, DRD2
20testosterone32 9 18 9 11.0PRL, SST, GNRH1, PCNA, CGA, MKI67
21clomiphene citrate32 8.0IGF1, CGA, GH1, PRL, ESR1, GNRH1
22triiodothyronine32 7.9GH1, IGF1, CGA, LEP, PRL, GHR
23clonidine32 9 9 9.9SST, CGA, IGF1, PRL, GH1, GHR
24acetylcholine32 9 18 9 10.8ADM, CORT, SST, GH1, DRD2, GNRH1
25leuprolide acetate32 7.7ESR1, PRL, CGA, IGF1, GNRH1, GHR
26estradiol32 9 18 9 10.7CGA, ESR1, PRL, MKI67, PCNA, POMC
27dehydroepiandrosterone sulfate32 7.7CGA, IGF1, GNRH1, LEP, POMC, GH1
28hydrocortisone32 9 9 9.7IGF1, ADM, POMC, SST, PRL, STAT5A
29androstenedione32 18 8.6LEP, CGA, POMC, PRL, GHR, GH1
30thymidine32 18 8.6IGF1, SSTR5, SSTR2, ADM, STAT5A, MKI67
31naloxone32 34 9 9 10.5ESR1, GH1, LEP, CGA, GNRH1, POMC
32creatinine32 7.3LEP, CGA, IGF1, GH1, GHR, PCNA
33dihydrotestosterone32 9 18 9 10.3LEP, PRL, CGA, IGF1, GNRH1, GH1
34adenylate32 7.3SST, PTPN3, DRD2, GNRH1, GNAS, GPR182
35progestin32 7.2GNRH1, PRL, POMC, GAPDH, CGA, IGF1
36thyroxine32 18 8.0SST, LEP, CGA, IGF1, GNRH1, POMC
37norepinephrine32 9 18 9 10.0APC, LEP, GNAS, GNRH1, GAPDH, GH1
38ribonucleic acid32 6.9GAPDH, CGA, POMC, PRL, SSTR5, SSTR4
39acth32 6.6PRL, CORT, SSTR5, SSTR2, SST, GHR
40dexamethasone32 42 34 9 9 10.5ADM, GNRH1, LEP, IGF1, GH1, GHR
41paraffin32 6.5APC, SSTR1, GHR, PCNA, GH1, ESR1
42arginine32 6.1PCNA, LEP, CGA, MKI67, IGF1, GNAS
43cycloheximide32 6.1ESR1, CGA, GH1, GAPDH, GHR, MKI67
44retinoic acid32 42 18 8.0ADM, APC, STAT5A, RXRG, SST, HMGA2
45octreotide32 42 9 9 9.0SSTR4, SSTR5, CORT, PRL, POMC, GAPDH
46vegf32 5.9PCNA, LEP, CGA, MKI67, IGF1, ESR1
47tamoxifen32 34 9 9 8.9GH1, ESR1, GNRH1, IGF1, MKI67, CGA
48steroid32 5.8MKI67, ADM, LEP, CGA, IGF1, GNAS
49progesterone32 42 9 18 9 9.0ADM, POMC, STAT5A, SSTR2, GNAS, IGF1
50estrogen32 4.6LEP, CGA, GAPDH, ADM, POMC, PRL

GO Terms for genes affiliated with Functioning Pituitary Adenoma

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12Gene Ontology
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Cellular components related to functioning pituitary adenoma according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056157.6POMC, CORT, SST, GHR, GH1, GNRH1
2extracellular regionGO:0055766.2SCGN, ADM, POMC, PRL, SST, GHR

Biological processes related to functioning pituitary adenoma according to GeneDecks:

(show all 24)
idNameGO IDScoreTop Affiliating Genes
1cellular response to glucocorticoid stimulusGO:07138510.3SSTR5, SSTR3, SSTR2
2response to starvationGO:04259410.2SSTR2, SSTR3, ADM
3adenylate cyclase-inhibiting G-protein coupled receptor signaling pathwayGO:00719310.1CORT, SSTR5, SSTR2, GNAI2
4isoleucine metabolic processGO:00654910.1STAT5A, GHR
5allantoin metabolic processGO:00025510.1STAT5A, GHR
6somatostatin signaling pathwayGO:03817010.1SSTR1, SSTR2, SSTR3, SSTR4, SSTR5
7induction of apoptosis by hormonesGO:00862810.1SSTR3, SST
8G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messengerGO:00718710.0SSTR5, SSTR4, SSTR3, SSTR2, SSTR1
9response to nutrientGO:00758410.0GNAI2, SST, SSTR1, SSTR2
10creatinine metabolic processGO:04644910.0STAT5A, GHR
11taurine metabolic processGO:01953010.0STAT5A, GHR
12valine metabolic processGO:00657310.0GHR, STAT5A
13JAK-STAT cascadeGO:0072599.9STAT5A, GHR, GH1
14positive regulation of tyrosine phosphorylation of Stat3 proteinGO:0425179.8GHR, GH1, LEP
15bone mineralization involved in bone maturationGO:0356309.8IGF1, LEP
16positive regulation of multicellular organism growthGO:0400189.8STAT5A, DRD2, GHR, GH1
17positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425239.7GHR, GH1, IGF1
18negative regulation of vasoconstrictionGO:0459069.6LEP, ADM
19JAK-STAT cascade involved in growth hormone signaling pathwayGO:0603979.4PRL, STAT5A, GHR, GH1
20regulation of multicellular organism growthGO:0400149.1PRL, STAT5A, GHR, IGF1
21female pregnancyGO:0075658.8ADM, PRL, STAT5A, GNRH1, GNAS, LEP
22cell-cell signalingGO:0072678.8ADM, POMC, SSTR3, SSTR2, SSTR1, SST
23negative regulation of cell proliferationGO:0082858.2SSTR3, SSTR4, SSTR5, ADM, SSTR2, SSTR1
24positive regulation of transcription from RNA polymerase II promoterGO:0459447.8POMC, STAT5A, RXRG, DRD2, HMGA2, ESR1

Molecular functions related to functioning pituitary adenoma according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1somatostatin receptor activityGO:0049949.6SSTR5, SSTR4, SSTR3, SSTR2, SSTR1
2prolactin receptor bindingGO:0051489.3GH1, PRL
3hormone activityGO:0051797.2LEP, ADM, POMC, PRL, SST, GH1
4protein bindingGO:0055155.3HMGA2, DRD2, PTPN3, SSTR2, SSTR3, STAT5A

Sources for Functioning Pituitary Adenoma

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2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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