MCID: GLL017
MIFTS: 47

Gallbladder Adenocarcinoma malady

Summaries for Gallbladder Adenocarcinoma

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MalaCards: Gallbladder Adenocarcinoma, also known as adenocarcinoma of the gallbladder, is related to adenocarcinoma and papillary adenocarcinoma. An important gene associated with Gallbladder Adenocarcinoma is MUC2 (mucin 2, oligomeric mucus/gel-forming), and among its related pathways are IL-3 Signaling Pathway and TGF-Beta Pathway. The compounds butyrate and o-tyrosine have been mentioned in the context of this disorder. Affiliated tissues include lymph node, colon and liver, and related mouse phenotypes are embryogenesis and integument.

Aliases & Classifications for Gallbladder Adenocarcinoma

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8Disease Ontology, 60UMLS, 39NCIt
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Aliases & Descriptions:

gallbladder adenocarcinoma 8 60
adenocarcinoma of the gallbladder 8


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Disease Ontology8 DOID:3500
NCIt39 C9166

Related Diseases for Gallbladder Adenocarcinoma

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17GeneCards, 18GeneDecks
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Diseases related to Gallbladder Adenocarcinoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 131)
idRelated DiseaseScoreTop Affiliating Genes
1adenocarcinoma31.3JAK2, CHGA, MYC, TYMP, MUC2, MUC1
2papillary adenocarcinoma30.5MUC2, MUC1, NME1
3gallbladder cancer30.4KRAS, MUC2
4large cell carcinoma30.4CHGA, KRAS, ERBB2
5gastric adenocarcinoma30.2CHGA, MYC, TYMP, MUC2, NME1, KRAS
6pneumonia30.2MUC1
7hepatitis30.2TYMP, KRAS
8hepatocellular carcinoma30.1TYMP, MUC2, CD82, NME1, KRAS, PTK2B
9gastrointestinal stromal tumor30.0IFI27
10hypertension30.0SELE
11signet ring cell adenocarcinoma30.0CHGA, MUC2
12adenosquamous carcinoma30.0NME1, MUC1, MUC2, TYMP, CHGA
13ulcerative colitis30.0MUC2, SRC, LAMC2, SELE
14leukemia29.9IFI27, SOAT1, JAK2, MYC, TYK2, CD82
15adenoma29.9MUC2, MYC, CHGA, IFI27, BRAF, MUC1
16neuroendocrine carcinoma10.4
17acanthosis nigricans10.3
18cholecystitis10.2
19xanthogranulomatous cholecystitis10.1
20acute interstitial pneumonia10.1
21gallbladder small cell carcinoma10.1
22gallbladder pleomorphic giant cell adenocarcinoma10.1
23small cell carcinoma10.1
24choledochal cyst10.1
25bile duct mucinous adenocarcinoma10.1
26bile duct adenocarcinoma10.1
27acalculous cholecystitis10.0
28gallbladder signet ring cell adenocarcinoma10.0
29adenosquamous gallbladder carcinoma10.0
30mucinous adenocarcinoma10.0
31sclerosing cholangitis10.0
32cholangitis10.0
33chronic lymphocytic leukemia10.0
34meningitis10.0
35ampulla of vater neoplasm10.0MUC2
36pancreatitis10.0KRAS
37endometriosis10.0TYMP
38leiomyoma10.0TYMP
39ductal carcinoma in situ10.0ERBB2
40neurofibromatosis10.0KRAS
41gastritis10.0CHGA
42rhabdoid tumor10.0MUC1
43angiosarcoma10.0MUC1
44laryngeal squamous cell carcinoma10.0NME1, IFI27
45biliary papillomatosis10.0MUC2
46oral cancer10.0CD82, IFI27
47myelofibrosis10.0JAK2
48juvenile myelomonocytic leukemia10.0KRAS
49leiomyosarcoma10.0MUC1
50cervical squamous cell carcinoma10.0KRAS, TYMP

Graphical network of the top 20 diseases related to Gallbladder Adenocarcinoma:



Diseases related to gallbladder adenocarcinoma

Clinical Features for Gallbladder Adenocarcinoma

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Drugs & Therapeutics for Gallbladder Adenocarcinoma

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Gallbladder Adenocarcinoma

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Genetic Tests for Gallbladder Adenocarcinoma

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Anatomical Context for Gallbladder Adenocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Gallbladder Adenocarcinoma:

32
Lymph node, Colon, Liver

Animal Models for Gallbladder Adenocarcinoma or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Gallbladder Adenocarcinoma:

36 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000538010.3ERBB2
2MP:001077110.1SOAT1, MYC, NME1, KRAS
3MP:000539010.0JAK2, MYC, TYK2, LAMC2
4MP:00053799.8SOAT1, JAK2, MYC, MUC2, NME1, KRAS
5MP:00053769.8SOAT1, TYK2, MUC2, MCAM, PTK2B, SELE
6MP:00053819.5BRAF, MYC, MUC2, MUC1, KRAS, LAMC2
7MP:00053709.5BRAF, SOAT1, MYC, MUC1, NME1, KRAS
8MP:00036319.3MYC, TYMP, EPHA7, NME1, SRC, ERBB2
9MP:00020069.3ERBB2, BRAF, SOAT1, JAK2, MYC, MUC2
10MP:00053979.2MYC, JAK2, SOAT1, BRAF, TYK2, MUC2
11MP:00053859.1BRAF, SOAT1, CHGA, MYC, MUC2, MCAM
12MP:00107689.0TYK2, MYC, CHGA, JAK2, BRAF, MUC2
13MP:00053788.9BRAF, JAK2, CHGA, MYC, MUC2, NME1
14MP:00053848.9BRAF, SOAT1, JAK2, MYC, TYMP, TYK2
15MP:00053878.7BRAF, SOAT1, JAK2, MYC, TYMP, TYK2

Publications for Gallbladder Adenocarcinoma

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50PubMed
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Articles related to Gallbladder Adenocarcinoma:

(show top 50)    (show all 106)
idTitleAuthorsYear
1
Antiproliferative and apoptosis-inducing activity of curcumin against human gallbladder adenocarcinoma cells. (23645731)
2013
2
Expression of Cell Cycle-Related Proteins, p16, p53 and p63 as Important Prognostic Markers in Gallbladder Adenocarcinoma. (24178677)
2013
3
Cutaneous metastasis of gallbladder adenocarcinoma in a patient with chronic lymphocytic leukemia: a case report and review of the literature. (23467457)
2013
4
Cheek metastasis from gallbladder adenocarcinoma. (23669176)
2013
5
Immunohistochemical expression of phospho-mTOR is associated with poor prognosis in patients with gallbladder adenocarcinoma. (23544944)
2013
6
ILK and PRDX1 are prognostic markers in squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder. (23065574)
2013
7
Impact of adjuvant external beam radiotherapy on survival in surgically resected gallbladder adenocarcinoma: A propensity score-matched Surveillance, Epidemiology, and End Results analysis. (23876364)
2013
8
PSCA and Oct-4 expression in the benign and malignant lesions of gallbladder: implication for carcinogenesis, progression, and prognosis of gallbladder adenocarcinoma. (23984394)
2013
9
Nectin-2 and DDX3 are biomarkers for metastasis and poor prognosis of squamous cell/adenosquamous carcinomas and adenocarcinoma of gallbladder. (23330003)
2013
10
CFL1 and Arp3 are biomarkers for metastasis and poor prognosis of squamous cell/adenosquamous carcinomas and adenocarcinomas of gallbladder. (23320827)
2013
11
A case of huge papillary adenocarcinoma of the gallbladder with marked necrosis]. (23303235)
2013
12
Adenocarcinoma of gallbladder: an immunohistochemical profile and comparison with cholangiocarcinoma. (23268317)
2013
13
Identification of CD146 expression, angiogenesis, and lymphangiogenesis as progression, metastasis, and poor-prognosis related markers for gallbladder adenocarcinoma. (22076922)
2012
14
Gallbladder adenocarcinoma: evaluation of the prognostic factors in 100 resectable cases in Brazil. (22569972)
2012
15
Mutations in the RAS/RAF/MAP kinase pathway commonly occur in gallbladder adenomas but are uncommon in gallbladder adenocarcinomas. (21307665)
2011
16
Does impaired gallbladder function contribute to the development of Barrett's esophagus and esophageal adenocarcinoma? (21484485)
2011
17
Cholecystocolic fistula of Crohn disease mimics colon adenocarcinoma invasion of gallbladder on F-18 FDG PET/CT. (21825838)
2011
18
Giant gallbladder: adenocarcinoma complicated with empyema. (21217498)
2011
19
Identification of PEG10 and TSG101 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma. (21455631)
2011
20
Claudin-7-positive synchronous spontaneous intrahepatic cholangiocarcinoma, adenocarcinoma and adenomas of the gallbladder in a Bearded dragon (Pogona vitticeps). (21354945)
2011
21
Ala499Val (C>T) and Lys939Gln (A>C) polymorphisms of the XPC gene: their correlation with the risk of primary gallbladder adenocarcinoma--a case-control study in China. (21113018)
2011
22
Curative resection of combined neuroendocrine carcinoma and adenocarcinoma of the gallbladder. (22322853)
2011
23
Identification of musashi-1 and ALDH1 as carcinogenesis, progression, and poor-prognosis related biomarkers for gallbladder adenocarcinoma. (22012766)
2010-2011
24
Invasive micropapillary variant of the gallbladder adenocarcinoma and its aggressive potential for lymph node metastasis. (20460736)
2010
25
Gallbladder adenocarcinoma with human chorionic gonadotropin: a case report and review of literature. (20594358)
2010
26
Gene amplification of Myc and its coamplification with ERBB2 and EGFR in gallbladder adenocarcinoma. (19331129)
2009
27
Wall-invasion pattern correlates with survival of patients with gallbladder adenocarcinoma. (19331223)
2009
28
Spontaneous necrosis of solid gallbladder adenocarcinoma accompanied with pancreaticobiliary maljunction. (18855999)
2008
29
Mucin-producing gallbladder adenocarcinoma with focal small cell and large cell neuroendocrine differentiation associated with pancreaticobiliary maljunction. (19067853)
2008
30
Gallbladder adenocarcinoma arising in Rokitansky-Aschoff sinus. (19067858)
2008
31
Clinicopathologic features of gallbladder adenocarcinoma with marked stromal fibrosis--a report of 19 cases]. (16831286)
2006
32
A case of lepidic pulmonary metastasis from adenocarcinoma of the gallbladder mimicking acute interstitial pneumonia. (16223618)
2005
33
Absence of therapeutic efficacy of the somatostatin analogue lanreotide in advanced primary hepatic cholangiocellular cancer and adenocarcinoma of the gallbladder despite in vivo somatostatin-receptor expression. (11843061)
2002
34
Thymidine phosphorylase expression in gallbladder adenocarcinomas. (12232571)
2002
35
Resection of triple synchronous tumors--gastric adenocarcinoma, gallbladder adenocarcinoma and stromal tumor of the stomach. (11853221)
2001
36
Fine needle aspiration cytology in xanthogranulomatous cholecystitis, gallbladder adenocarcinoma and coexistent lesions. (10934941)
2000
37
Hepatoid adenocarcinoma of the gallbladder. (10982619)
2000
38
v-src induces cisplatin resistance by increasing the repair of cisplatin-DNA interstrand cross-links in human gallbladder adenocarcinoma cells. (10048975)
1999
39
Subacute pulmonary hypertension due to pulmonary tumor microembolism as a clinical manifestation of occult gallbladder adenocarcinoma. (9070964)
1997
40
Gallbladder adenocarcinoma and acalculous chronic lymphoplasmacytic cholecystitis associated with ulcerative colitis [corrected]. (8685213)
1996
41
Small-cell carcinoma combined with adenocarcinoma of the gallbladder. A case report with immunohistochemical and flow cytometric studies. (8311660)
1994
42
Gallbladder adenocarcinoma with gallstone and calcified ova of clonorchis sinensis--a case report. (8205506)
1994
43
Adenocarcinoma of the gallbladder associated with congenital choledochal cyst and anomalous pancreaticobiliary ductal junction. Case report. (1683581)
1991
44
Xanthogranulomatous cholecystitis associated with gallbladder adenocarcinoma. A clinicopathological study of 5 cases. (1746061)
1991
45
Dysplasia of the gallbladder. Its histogenesis and correlation to gallbladder adenocarcinoma. (2602218)
1989
46
Simultaneous xanthogranulomatous cholecystitis and primary adenocarcinoma of gallbladder. (3417248)
1988
47
Acanthosis nigricans associated with adenocarcinoma of the gallbladder. (4050764)
1985
48
Papillary adenocarcinoma of the gallbladder. (3974509)
1985
49
A human gallbladder adenocarcinoma cell line. (7262900)
1981
50
Acanthosis nigricans and the sign of Leser-TrAclat associated with adenocarcinoma of the gallbladder. (7237403)
1981

Genetic Variations for Gallbladder Adenocarcinoma

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Expression for genes affiliated with Gallbladder Adenocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gallbladder Adenocarcinoma

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Pathways for genes affiliated with Gallbladder Adenocarcinoma

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Sources:
37NCBI BioSystems Database, 51QIAGEN, 12EMD Millipore, 53Reactome, 29KEGG, 4Cell Signaling Technology, 55SinoBiological, 49PharmGKB, 52R&D Systems
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Pathways related to Gallbladder Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 66)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.2SRC, TYK2
2
Hide members
10.2ERBB2, EPHA7
3
Hide members
10.1SRC, PTK2B
410.1SRC, ERBB2, LAMC2
510.0TYK2, JAK2, SRC
610.0JAK2, TYK2, SRC
710.0SRC, TYK2, JAK2
810.0TYK2, MYC, JAK2
910.0JAK2, TYK2, MYC
10
Hide members
10.0KRAS, SRC, BRAF
1110.0BRAF, MYC, KRAS
12
Development EPO-induced Jak-STAT pathway
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10.0MYC, JAK2, SRC
1310.0JAK2, TYK2, PTK2B
1410.0JAK2, PTK2B, KRAS
1510.0SRC, PTK2B, ERBB2
169.9SRC, PTK2B, JAK2
17
Hide members
9.9JAK2, SRC, KRAS, ERBB2
189.9MUC1, JAK2, SRC, ERBB2
19
Hide members
9.9PTK2B, KRAS, TYK2, JAK2
20
Hide members
9.9ERBB2, KRAS, BRAF, MYC
219.8PTK2B, JAK2, TYK2, ERBB2
22
Hide members
9.8ERBB2, KRAS, SRC, PTK2B
239.8SRC, BRAF, JAK2, MYC
24
Hide members
9.8PTK2B, SRC, KRAS, MYC
25
Immune response IFN gamma signaling pathway
Hide members
9.8JAK2, PTK2B, SRC, MYC
269.7ERBB2, LAMC2, KRAS, MYC, BRAF
27
Hide members
9.7BRAF, KRAS, TYMP, MYC, SRC
28
Hide members
9.7SELE, KRAS, SRC, BRAF, JAK2
29
Development Prolactin receptor signaling
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9.7ERBB2, JAK2, MYC, KRAS, SRC
30
Hide members
9.7BRAF, MYC, KRAS, SRC, ERBB2
319.7KRAS, SRC, BRAF, ERBB2, MYC
32
Hide members
9.7KRAS, MYC, BRAF, ERBB2, SRC
33
Development PDGF signaling via STATs and NF-kB
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9.7SRC, TYK2, JAK2, MYC, PTK2B
34
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9.7BRAF, MYC, JAK2, SRC, ERBB2
35
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9.7PTK2B, ERBB2, SRC, LAMC2, BRAF
36
Hide members
9.7KRAS, PTK2B, JAK2, IFI27, TYK2
379.6PTK2B, MYC, KRAS, SRC, JAK2
38
Hide members
9.6JAK2, KRAS, SRC, PTK2B, BRAF
39
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9.6SRC, PTK2B, BRAF, JAK2, KRAS
40
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9.6BRAF, ERBB2, PTK2B, SRC, JAK2
41
Hide members
9.6EPHA7, SRC, JAK2, MYC, TYK2, ERBB2
429.6MYC, ERBB2, SRC, KRAS, NME1, CD82
43
G-protein signaling Ras family GTPases in kinase cascades (scheme)
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9.5SRC, TYK2, PTK2B, JAK2, BRAF, KRAS
44
Hide members
9.5JAK2, ERBB2, MYC, MUC1, SRC, BRAF
45
Translation Insulin regulation of translation
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9.5PTK2B, BRAF, JAK2, KRAS, SRC, ERBB2
46
Hide members
9.5MYC, SRC, LAMC2, BRAF, PTK2B, JAK2
47
Hide members
9.5MYC, KRAS, SRC, PTK2B, ERBB2, BRAF
48
Hide members
9.4BRAF, JAK2, MYC, TYK2, MUC1, KRAS
49
Hide members
9.3SRC, PTK2B, EPHA7, MYC, JAK2, BRAF
50
Hide members
9.1EPHA7, ERBB2, SRC, LAMC2, JAK2, BRAF

Compounds for genes affiliated with Gallbladder Adenocarcinoma

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44Novoseek, 49PharmGKB, 59Tocris Bioscience, 11DrugBank, 28IUPHAR, 24HMDB, 2BitterDB
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Compounds related to Gallbladder Adenocarcinoma according to GeneCards/GeneDecks:

(show top 50)    (show all 124)
idCompoundScoreTop Affiliating Genes
1butyrate4410.5JAK2
2o-tyrosine4410.3TYK2, ERBB2, JAK2
3crcs4410.1MUC2, MUC1, NME1, KRAS, TYMP, BRAF
4etoposide44 49 59 1113.1ERBB2, CHGA, SELE, PTK2B
5cycloheximide4410.1TYMP
6gemcitabine44 49 1112.0MYC, TYMP, MUC1, SRC, ERBB2
7matrigel4410.0SRC, NME1, SELE, MUC1, JAK2, BRAF
8erlotinib44 49 1112.0ERBB2, SRC, TYMP, KRAS
9vanadate4410.0SOAT1, PTK2B, SRC, TYK2, JAK2
10sodium orthovanadate44 5911.0TYK2, JAK2, PTK2B, SRC
11dexamethasone44 49 28 1112.9PTK2B, NME1, MUC2, MYC, SOAT1, IFI27
12folate449.9SELE, ERBB2, PTK2B, MUC1, TYMP, MYC
13p002449.9CHGA, ERBB2, KRAS, NME1, TYMP, IFI27
14dmso449.8CHGA, MYC, SELE, MUC2, MUC1, PTK2B
15herbimycin a44 5910.8SRC, JAK2, MYC, SELE, PTK2B, ERBB2
16aspirin44 49 28 2412.8PTK2B, TYMP, ERBB2, SELE, JAK2, SRC
1712-o-tetradecanoylphorbol 13-acetate449.8BRAF, JAK2, CHGA, TYMP, MUC2, MUC1
18serine449.7ERBB2, JAK2, MUC2, NME1, KRAS, SRC
19adp44 28 2411.7PTK2B, NME1, EPHA7, TYK2, JAK2
20guanine44 11 2411.7IFI27, SELE, ERBB2, PTK2B, SRC, TYMP
21phosphotyrosine449.7PTK2B, SOAT1, ERBB2, TYK2, SRC, JAK2
22sb 20358044 5910.7SELE, BRAF, PTK2B, JAK2, SRC, MUC2
23tamoxifen44 49 28 1112.7SELE, ERBB2, TYMP, MUC1, MYC, CHGA
24paclitaxel44 49 1111.6BRAF, IFI27, SRC, TYMP, ERBB2, CHGA
255fluorouracil449.6MUC2, SRC, KRAS, PTK2B, ERBB2, SELE
26agar449.6BRAF, MUC1, JAK2, MYC, NME1, SRC
27genistein44 28 59 2 11 2414.6PTK2B, SRC, JAK2, IFI27, SELE, MYC
28actinomycin d449.6MUC2, SOAT1, JAK2, PTK2B, MUC1, TYMP
29thymidine44 2410.6NME1, TYMP, MUC1, IFI27, MYC, PTK2B
30phosphoinositide449.6BRAF, IFI27, SOAT1, JAK2, KRAS, SRC
31imatinib44 49 1111.6ERBB2, PTK2B, SRC, KRAS, MYC, JAK2
32n acetylcysteine449.5SRC, ERBB2, PTK2B, MYC, JAK2, SOAT1
33progesterone44 59 28 11 2413.5NME1, BRAF, TYMP, IFI27, MUC2, CHGA
34pd 98,059449.5BRAF, SOAT1, MYC, MUC2, SRC, JAK2
35wortmannin449.5TYMP, ERBB2, PTK2B, BRAF, SOAT1, JAK2
36testosterone44 59 11 2412.5IFI27, SOAT1, CHGA, SRC, PTK2B, SELE
37oligonucleotide449.4IFI27, BRAF, JAK2, CHGA, SOAT1, MYC
38cysteine449.4MUC2, NME1, SRC, TYMP, JAK2, PTK2B
39rapamycin449.4ERBB2, BRAF, IFI27, SOAT1, JAK2, MYC
40paraffin449.3MYC, TYMP, KRAS, ERBB2, MUC2, MUC1
41Adenosine triphosphate11 2410.3JAK2, TYK2, EPHA7, NME1, SRC, PTK2B
42alanine449.3PTK2B, SOAT1, JAK2, MYC, TYK2, NME1
43threonine449.2SOAT1, JAK2, MYC, TYK2, MUC2, MUC1
44phosphatidylinositol449.2BRAF, SOAT1, JAK2, MYC, TYK2, KRAS
45cyclic amp44 2410.1BRAF, IFI27, SOAT1, CHGA, MUC1, MCAM
46ly294002449.1MYC, BRAF, IFI27, JAK2, TYMP, TYK2
47cisplatin44 49 59 1112.1SRC, TYMP, MYC, CHGA, JAK2, IFI27
48retinoic acid44 2410.1NME1, PTK2B, MYC, KRAS, MUC1, CHGA
49vegf448.7BRAF, IFI27, SOAT1, JAK2, SELE, PTK2B
50tyrosine448.3MYC, MCAM, ERBB2, BRAF, IFI27, SOAT1

GO Terms for genes affiliated with Gallbladder Adenocarcinoma

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16Gene Ontology
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Cellular components related to Gallbladder Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1caveolaGO:00590110.0SELE, SRC, JAK2
2membrane raftGO:0451219.5SELE, PTK2B, KRAS, JAK2

Biological processes related to Gallbladder Adenocarcinoma according to GeneCards/GeneDecks:

(show all 16)
idNameGO IDScoreTop Affiliating Genes
1enzyme linked receptor protein signaling pathwayGO:00716710.3ERBB2, JAK2
2activation of MAPKK activityGO:00018610.3KRAS, JAK2, BRAF
3positive regulation of epithelial cell proliferationGO:05067910.3MYC, NME1, ERBB2
4signal complex assemblyGO:00717210.3PTK2B, SRC
5peptidyl-tyrosine phosphorylationGO:01810810.2JAK2, SRC, PTK2B
6regulation of ERK1 and ERK2 cascadeGO:07037210.2ERBB2, EPHA7
7MAPK cascadeGO:00016510.2PTK2B, KRAS, MYC
8fibroblast growth factor receptor signaling pathwayGO:00854310.1BRAF, KRAS, SRC, ERBB2
9positive regulation of nitric-oxide synthase activityGO:05100010.1PTK2B, KRAS
10protein autophosphorylationGO:04677710.1JAK2, SRC, PTK2B, ERBB2
11epidermal growth factor receptor signaling pathwayGO:00717310.1ERBB2, PTK2B, SRC, KRAS
12cytokine-mediated signaling pathwayGO:01922110.1IFI27, JAK2, TYK2, KRAS
13protein phosphorylationGO:00646810.0ERBB2, PTK2B, TYK2, JAK2, BRAF
14intracellular protein kinase cascadeGO:0072439.9JAK2, TYK2, SRC
15neurotrophin TRK receptor signaling pathwayGO:0480119.9BRAF, KRAS, SRC, ERBB2
16positive regulation of ERK1 and ERK2 cascadeGO:0703749.6PTK2B, SRC, BRAF

Molecular functions related to Gallbladder Adenocarcinoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1growth hormone receptor bindingGO:00513110.2TYK2, JAK2
2non-membrane spanning protein tyrosine kinase activityGO:0047159.8JAK2, TYK2, SRC, PTK2B
3protein tyrosine kinase activityGO:0047139.6ERBB2, PTK2B, SRC, EPHA7, TYK2, JAK2
4ATP bindingGO:0055249.0BRAF, JAK2, TYK2, EPHA7, NME1, SRC
5protein bindingGO:0055158.1BRAF, SOAT1, JAK2, MYC, TYK2, MUC2

Products for genes affiliated with Gallbladder Adenocarcinoma

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Sources for Gallbladder Adenocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet