MCID: GLL020
MIFTS: 59

Gallbladder Disease malady

Categories: Gastrointestinal diseases, Nephrological diseases, Genetic diseases, Liver diseases, Rare diseases

Aliases & Classifications for Gallbladder Disease

Aliases & Descriptions for Gallbladder Disease:

Name: Gallbladder Disease 12 29 29 14
Gallbladder Diseases 41 42
Gall Bladder Diseases 69
Gall Bladder 52

Classifications:



External Ids:

Disease Ontology 12 DOID:0060262
ICD10 33 K82.9 K82.8
ICD9CM 35 575.9
MeSH 42 D005705
NCIt 47 C34631
UMLS 69 C0016977

Summaries for Gallbladder Disease

MedlinePlus : 41 your gallbladder is a pear-shaped organ under your liver. it stores bile, a fluid made by your liver to digest fat. as your stomach and intestines digest food, your gallbladder releases bile through a tube called the common bile duct. the duct connects your gallbladder and liver to your small intestine. your gallbladder is most likely to give you trouble if something blocks the flow of bile through the bile ducts. that is usually a gallstone. gallstones form when substances in bile harden. rarely, you can also get cancer in your gallbladder. many gallbladder problems get better with removal of the gallbladder. fortunately, you can live without a gallbladder. bile has other ways of reaching your small intestine.

MalaCards based summary : Gallbladder Disease, also known as gallbladder diseases, is related to gallbladder disease 4 and dyspepsia, and has symptoms including abdominal pain, constipation and diarrhea. An important gene associated with Gallbladder Disease is CCK (Cholecystokinin), and among its related pathways/superpathways are Glucose / Energy Metabolism and Folate Metabolism. The drugs Dopamine and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include liver, small intestine and breast, and related phenotypes are Decreased free cholesterol and cardiovascular system

Disease Ontology : 12 A gastrointestinal system disease that is located in the gallbladder.

Wikipedia : 71 Gallbladder diseases are diseases involving the... more...

Related Diseases for Gallbladder Disease

Diseases in the Gallbladder Disease family:

Gallbladder Disease 2 Gallbladder Disease 3
Gallbladder Disease 4 Gallbladder Disease 1

Diseases related to Gallbladder Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 103)
id Related Disease Score Top Affiliating Genes
1 gallbladder disease 4 33.1 ABCG8 APOB SOAT1
2 dyspepsia 29.5 CCK MECP2
3 myocardial infarction 28.8 APOA1 APOB APOE IL10 INS
4 gallbladder disease 1 12.1
5 gall bladder carcinoma in situ 12.0
6 gallbladder disease 2 11.8
7 gallbladder disease 3 11.8
8 common bile duct disease 11.1
9 biliary dyskinesia 10.7
10 zap-70 deficiency 10.2 APOB APOE
11 keratoconus 4 10.2 APOB APOE
12 iron metabolism disease 10.2 ABCG8 APOE
13 familial progressive cardiac conduction defect 10.2 APOA1 APOE
14 dentinogenesis imperfecta type 2 10.2 APOB APOE
15 hyperchlorhidrosis, isolated 10.2 APOA1 APOE
16 anhidrosis 10.2 ABCB4 CCK
17 pars planitis 10.2 APOA1 APOE
18 fetal warfarin syndrome 10.1 APOA1 APOB INS
19 albinism, oculocutaneous, type v 10.1 APOA1 APOB APOE
20 neonatal hypoxic and ischemic brain injury 10.1 APOA1 IL10
21 dyserythropoietic anemia, congenital, type ii 10.1 ABCB4 APOA1 APOE
22 bird fancier's lung 10.1 APOA1 APOB APOE
23 skin squamous cell carcinoma 10.1 APOA1 APOB APOE
24 stone in bladder diverticulum 10.1 APOA1 APOB APOE
25 c1s deficiency 10.1 APOE INS
26 gait apraxia 10.1 APOA1 APOB APOE
27 von willebrand disease, platelet-type 10.1 APOA1 APOB APOE
28 mannosidosis, beta 10.1 APOA1 APOB APOE
29 optic nerve neoplasm 10.1 APOA1 APOB APOE
30 neuropathy, hereditary sensory and autonomic, type ia 10.1 APOA1 APOB APOE
31 cetp-related hyperalphalipoproteinemia 10.1 APOB APOE INS
32 hypertriglyceridemia 10.1 APOA1 APOB APOE
33 cataract 5, multiple types 10.1 APOA1 APOB APOE
34 alzheimer disease 19, late onset 10.1 APOB APOE
35 obesity 10.1
36 body dysmorphic disorder 10.1 APOA1 APOB INS
37 tuberculous peritonitis 10.0 CCK CCKAR IL10
38 posterior uveal melanoma 10.0 APOA1 APOB INS UGT1A1
39 joint disorders 10.0 APOA1 APOB APOE INS
40 chondrocalcinosis with early-onset osteoarthritis 10.0 APOA1 APOB APOE INS
41 bleeding disorder, east texas type 10.0 APOA1 APOB APOE INS
42 acute apical periodontitis 10.0 APOA1 APOB APOE INS
43 lacrimal system cancer 10.0 CCK CCKAR IL10
44 lipomatosis 10.0 APOA1 APOB APOE INS
45 immunodeficiency 18 10.0 APOA1 APOB APOE INS
46 cervix small cell carcinoma 10.0 APOA1 APOB APOE INS
47 pyrimidine metabolic disorder 10.0 APOA1 APOB APOE INS
48 pericarditis 9.9 APOA1 APOB APOE INS
49 macular degeneration, age-related, 12 9.9 APOA1 APOB APOE INS
50 severe intellectual disability-progressive postnatal microcephaly- midline stereotypic hand movements syndrome 9.9 APOB APOE SOAT1

Comorbidity relations with Gallbladder Disease via Phenotypic Disease Network (PDN):


Acute Cystitis Acute Pancreatitis
Esophagitis Heart Disease
Hypertension, Essential Intermediate Coronary Syndrome
Ischemic Heart Disease

Graphical network of the top 20 diseases related to Gallbladder Disease:



Diseases related to Gallbladder Disease

Symptoms & Phenotypes for Gallbladder Disease

UMLS symptoms related to Gallbladder Disease:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, icterus, nausea and vomiting, gastrointestinal gas

GenomeRNAi Phenotypes related to Gallbladder Disease according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased free cholesterol GR00340-A-2 9.02 ABCG8 APOA1 APOB APOE GCKR

MGI Mouse Phenotypes related to Gallbladder Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.97 ABCB4 APOA1 APOB APOE IL10 INS
2 cellular MP:0005384 9.97 MECP2 ABCB4 ABCG8 APOA1 APOB APOE
3 endocrine/exocrine gland MP:0005379 9.81 ABCB4 APOA1 APOE CCK CCKAR IL10
4 digestive/alimentary MP:0005381 9.73 ABCB4 ABCG8 APOE CCKAR IL10 INS
5 homeostasis/metabolism MP:0005376 9.73 INS MECP2 SOAT1 ABCB4 ABCG8 APOA1
6 liver/biliary system MP:0005370 9.32 ABCB4 ABCG8 APOA1 APOB APOE CCKAR

Drugs & Therapeutics for Gallbladder Disease

Drugs for Gallbladder Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 443)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
2
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
3
Lidocaine Approved, Vet_approved Phase 4 137-58-6 3676
4
Flurbiprofen Approved, Investigational Phase 4 5104-49-4 3394
5
Oxaliplatin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 61825-94-3 5310940 9887054 6857599, 9887054 43805
6
Remifentanil Approved Phase 4 132875-61-7 60815
7
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
8
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
9
Tramadol Approved, Investigational Phase 4 27203-92-5 33741
10
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
11
Droperidol Approved, Vet_approved Phase 4 548-73-2 3168
12
Ropivacaine Approved Phase 4 84057-95-4 71273 175805
13
Midazolam Approved, Illicit Phase 4 59467-70-8 4192
14
chenodeoxycholic acid Approved Phase 4,Phase 2 474-25-9 10133
15
Ursodeoxycholic acid Approved, Investigational Phase 4,Phase 3 128-13-2 31401
16
Ciprofloxacin Approved, Investigational Phase 4 85721-33-1 2764
17
Morphine Approved, Investigational Phase 4,Phase 1 57-27-2 5288826
18
Acetaminophen Approved Phase 4 103-90-2 1983
19
Ibuprofen Approved Phase 4 15687-27-1 3672
20
Neostigmine Approved, Vet_approved Phase 4 59-99-4 4456
21
Atropine Approved, Vet_approved Phase 4 5908-99-6, 51-55-8 174174
22
Rocuronium Approved Phase 4 119302-91-9, 143558-00-3 441290
23
Ceftriaxone Approved Phase 4 73384-59-5 5479530 5361919
24
Dexmedetomidine Approved, Vet_approved Phase 4 76631-46-4, 113775-47-6 68602 5311068 56032
25
Esmolol Approved Phase 4 103598-03-4, 81147-92-4 59768
26
Ephedrine Approved Phase 4 299-42-3 9294
27
Isoflurane Approved, Vet_approved Phase 4 26675-46-7 3763
28
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
29
Lactulose Approved Phase 4 4618-18-2 11333
30
Ondansetron Approved Phase 4 99614-02-5 4595
31
Bupivacaine Approved, Investigational Phase 4,Phase 3 2180-92-9, 38396-39-3 2474
32
Ketorolac Approved Phase 4 74103-06-3, 66635-83-4 3826
33
Minocycline Approved, Investigational Phase 4 10118-90-8 5281021
34
Amoxicillin Approved, Vet_approved Phase 4,Phase 3 26787-78-0 33613 2171
35
Metronidazole Approved Phase 4,Phase 1 443-48-1 4173
36
Etoricoxib Approved, Investigational Phase 4 202409-33-4 123619
37
Ampicillin Approved, Vet_approved Phase 4 69-53-4 6249
38
Pseudoephedrine Approved Phase 4 90-82-4 7028
39
Tigecycline Approved Phase 4 220620-09-7 5282044
40
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 4,Phase 3 437-38-7 3345
41
Meperidine Approved Phase 4 57-42-1 4058
42
Secretin Approved, Investigational Phase 4 108153-74-8
43
Desflurane Approved Phase 4 57041-67-5 42113
44
Levobupivacaine Approved Phase 4 27262-47-1 92253
45
Rifaximin Approved, Investigational Phase 4 80621-81-4 6436173
46
Cholecystokinin Approved Phase 4,Phase 3 9011-97-6
47
Tauroursodeoxycholic acid Approved, Investigational Phase 4 14605-22-2 12443252
48
Sulbactam Approved Phase 4 68373-14-8
49 tannic acid Approved, Nutraceutical Phase 4
50
Vitamin C Approved, Nutraceutical Phase 4 50-81-7 5785 54670067

Interventional clinical trials:

(show top 50) (show all 513)
id Name Status NCT ID Phase
1 SILS™ Port Laparoscopic Cholecystectomy Post Market Study Unknown status NCT00832767 Phase 4
2 Transvaginal Cholecystectomy Versus Laparoscopic Cholecystectomy in Patients With Biliary Colic Unknown status NCT00963950 Phase 4
3 Efficacy and Safety of Floseal for the Haemostasis During Laparoscopic Cholecystectomy in Acute Cholecystitis (GLA) Unknown status NCT01126281 Phase 4
4 Laparo-endoscopic Single Site (LESS) Cholecystectomy Versus Standard LAP-CHOLE Unknown status NCT01339325 Phase 4
5 Closed-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy Unknown status NCT02114437 Phase 4
6 Day-care Versus Overnight-stay Laparoscopic Cholecystectomy Randomized Controlled Trial. Unknown status NCT01052727 Phase 4
7 Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy Unknown status NCT00209885 Phase 4
8 Study of the Use of Humidified Warmed Gas and the Effect on Post-Operative Pain in Laparoscopic Cholecystectomies Unknown status NCT00792389 Phase 4
9 Effects of Calot's Triangle Block for Postoperative Analgesia in Patients Undergoing Laparoscopic Cholecystectomy: a Prospective, Randomized, Double-blind, Controlled, Clinical Trial Unknown status NCT02300480 Phase 4
10 Relationship Between Platinum Levels in the Blood and Neurotoxicity in Patients Who Are Receiving Oxaliplatin for Gastrointestinal Cancer Unknown status NCT00274885 Phase 4
11 The Effect of Intravenous Lidocaine and Intraperitoneal Lidocaine Irrigation on Pain After Laparoscopic Cholecystectomy Unknown status NCT01608373 Phase 4
12 A Study Comparing the Use of Deep or Standard Neuromuscular Blockade in Combination With Low or Standard Insufflation Pressures in Participants Undergoing Laparoscopic Cholecystectomy (P07982) Completed NCT01728584 Phase 4
13 Effect IV Ibuprofen and Inflammatory Responses Completed NCT01938040 Phase 4
14 Cocktail Sedation Containing Propofol Versus Conventional Sedation for Endoscopic Retrograde Cholangiopancreatography (ERCP) Completed NCT01540084 Phase 4
15 Efficacy and Safety Profiles of Combination Sedation Propofol With Midazolam and Meperidine. Completed NCT01709422 Phase 4
16 Minilaparoscopic Versus Conventional Laparoscopic Cholecystectomy Completed NCT01397565 Phase 4
17 Anesthesia With Propofol, Dexmedetomidine and Lidocaine Infusions for Laparoscopic Cholecystectomy Completed NCT01833819 Phase 4
18 Vitamin C Efficacy in Reducing Post Operative Pain Completed NCT01322061 Phase 4
19 Balloon Catheter vs. Basket Catheter for Endoscopic Bile Duct Stone Extraction Completed NCT02909595 Phase 4
20 UDCA for Symptomatic Gallstone Disease Completed NCT00161083 Phase 4
21 Cholecyst- Versus Cystic Duct Cholangiography During Laparoscopic Cholecystectomy Completed NCT01103570 Phase 4
22 Intraoperative Lidocaine Infusion vs. Esmolol Infusion for Postoperative Analgesia in Laparoscopic Cholecystectomy Completed NCT02327923 Phase 4
23 Multi-Port Versus Single-port Cholecystectomy Completed NCT01104727 Phase 4
24 Endovenous Lidocaine and Serum Cytokines Concentration Completed NCT02363699 Phase 4
25 Dual-Loop Target Controlled Infusion in Laparoscopic Cholecystectomy (DLTCI) Completed NCT02116985 Phase 4
26 Oxidative Stress in Standard Laparoscopic vs Single Port Cholecystectomy Completed NCT01211743 Phase 4
27 Levobupivacaine During Cholecystectomy Completed NCT00836316 Phase 4
28 Robotic Assisted Versus Laparoscopic Cholecystectomy - Outcome and Cost Analyses of a Case-Matched Control Study Completed NCT00562900 Phase 4
29 DGT Versus TPS in Patients With Initial PD Cannulation by Chance; Prospective Multi-center Study Completed NCT01744847 Phase 4
30 Biliary Metal Stent Study: Metal Stents for Management of Distal Malignant Biliary Obstruction Completed NCT00280709 Phase 4
31 Pain Reduction After Cholecystectomy Completed NCT01199406 Phase 4
32 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection Completed NCT00195351 Phase 4
33 Study Comparing Tigecycline Versus Ceftriaxone Sodium Plus Metronidazole in Complicated Intra-abdominal Infection (cIAI) Completed NCT00230971 Phase 4
34 Pain Post Abdominal Laparoscopy Prevention With Arcoxia Completed NCT00565682 Phase 4
35 Effect of Acupuncture on Postoperative Nausea and Vomiting Completed NCT00674713 Phase 4
36 The Safety/Efficacy Of Rifaximin With/Without Lactulose In Subjects With A History Of Recurrent Hepatic Encephalopathy Completed NCT01842581 Phase 4
37 Effect of Rowachol on Prevention of Postcholecystectomy Syndrome Completed NCT01765465 Phase 4
38 A Study Evaluating the Effect of Albiglutide on Gallbladder Emptying in Healthy Subjects Completed NCT02496221 Phase 4
39 A Study of Serial Magnetic Resonance Cholangiopancreatography (MRCP) Following Morphine-neostigmine and Secretin Provocation in Healthy Volunteers Completed NCT01134848 Phase 4
40 Effect of Intraperitoneal and Intravenous Lignocaine on Pain Relief Following Laparoscopic Cholecystectomy Completed NCT01717222 Phase 4
41 Endoscopic Treatment of Difficult Bile Duct Stones: Spyglass + EHL x Balloon Dilation of the Papilla Recruiting NCT02703077 Phase 4
42 Extended Antibiotic Therapy in Postoperative of Laparoscopic Cholecystectomy in Acute Cholecystitis Recruiting NCT02057679 Phase 4
43 Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia Recruiting NCT02493231 Phase 4
44 The Discovery of the Double Sphincter in Gallbladder Recruiting NCT01998451 Phase 4
45 Granisetron Effect on Hemodynamic Changes in Laparoscopic Cholecystectomy Recruiting NCT03180229 Phase 4
46 The Role of Ursodeoxycholic Acid in Treatment of Gallstones in Hemolytic Disorders Recruiting NCT02472509 Phase 4
47 Contrastive Study for Minimally Invasive Cholecystolithotomy With Gallbladder Reservation and Laparoscopic Cholecystectomy Recruiting NCT01822262 Phase 4
48 Deep Versus Moderate Neuromuscular Blockade During Laparoscopic Surgery Recruiting NCT02812186 Phase 4
49 Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery Recruiting NCT02174575 Phase 4
50 Changes in Bile Acid Homeostasis and Stool Habits After Cholecystectomy Not yet recruiting NCT03168555 Phase 4

Search NIH Clinical Center for Gallbladder Disease

Cochrane evidence based reviews: gallbladder diseases

Genetic Tests for Gallbladder Disease

Genetic tests related to Gallbladder Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Gallbladder 29
2 Gallbladder Dysfunction 29

Anatomical Context for Gallbladder Disease

MalaCards organs/tissues related to Gallbladder Disease:

39
Liver, Small Intestine, Breast, Heart, Testes, Colon, Spinal Cord

The Foundational Model of Anatomy Ontology organs/tissues related to Gallbladder Disease:

18
The Gallbladder

Publications for Gallbladder Disease

Articles related to Gallbladder Disease:

(show top 50) (show all 458)
id Title Authors Year
1
Physical Activity and the Risk of Gallbladder Disease: A Systematic Review and Meta-Analysis of Cohort Studies. ( 26901710 )
2016
2
A case report of symptomatic gallbladder disease in the setting of peritoneal carcinomatosis originating from invasive lobular carcinoma of the breast. ( 27180323 )
2016
3
MUC Expression in Gallbladder Epithelial Tissues in Cholesterol-Associated Gallbladder Disease. ( 27563024 )
2016
4
Diabetes mellitus and the risk of gallbladder disease: A systematic review and meta-analysis of prospective studies. ( 26684168 )
2016
5
Tobacco smoking and the risk of gallbladder disease. ( 26898907 )
2016
6
Functional gallbladder disease: Operative trends and short-term outcomes. ( 27129932 )
2016
7
Management of gallbladder disease after sleeve gastrectomy in a selected Lebanese population. ( 27178610 )
2016
8
Surgical options for gallbladder disease. ( 27062758 )
2016
9
The increasing incidence of gallbladder disease in children: A 20year perspective. ( 26951963 )
2016
10
Gallbladder disease in children. ( 27521713 )
2016
11
Vegetable protein intake is associated with lower gallbladder disease risk: Findings from the Women's Health Initiative prospective cohort. ( 27009631 )
2016
12
A cross-sectional study of cardiorespiratory fitness and gallbladder disease. ( 27955793 )
2016
13
Contrast-enhanced ultrasound in gallbladder disease: a pictorial review. ( 27056746 )
2016
14
A Prospective Study of the Conservative Management of Asymptomatic Preoperative and Postoperative Gallbladder Disease in Bariatric Surgery. ( 27324135 )
2016
15
Is transpapillary gallbladder stenting better than percutaneous cholecystostomy for the treatment of symptomatic gallbladder disease in decompensated cirrhotic patients? ( 25647724 )
2015
16
Polypoid lesions of the gallbladder: disease spectrum with pathologic correlation. ( 25763724 )
2015
17
Interventional Approaches to Gallbladder Disease. ( 26200981 )
2015
18
Polypoid Lesions of the Gallbladder: Disease Spectrum with Pathologic Correlationa89Erratum. ( 26172366 )
2015
19
Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array. ( 25920552 )
2015
20
Dietary patterns and risk of gallbladder disease: a hospital-based case-control study in adult women. ( 25995720 )
2015
21
Transvaginal cholecystectomy vs conventional laparoscopic cholecystectomy for gallbladder disease: A meta-analysis. ( 25954114 )
2015
22
Emergency Management of Gallbladder Disease: Are Acute Surgical Units the New Gold Standard? ( 26296834 )
2015
23
Body mass index, abdominal fatness and the risk of gallbladder disease. ( 26374741 )
2015
24
Implications of radiologic-pathologic correlation for gallbladder disease in children and young adults with sickle cell disease. ( 26109240 )
2015
25
Polypoid lesions of the gallbladder: disease spectrum with pathologic correlation-erratum. ( 25969942 )
2015
26
Novel Use of Long, Large-Caliber, Fenestrated Stents for Endoscopic Transpapillary Gallbladder Stenting for Therapy of Symptomatic Gallbladder Disease. ( 26233546 )
2015
27
Prevalence, clinical investigation, and management of gallbladder disease in Rett syndrome. ( 24528171 )
2014
28
Pain Provocation and Low Gallbladder Ejection Fraction with CCK Cholescintigraphy Are Not Predictive of Chronic Acalculous Gallbladder Disease Symptom Relief After Cholecystectomy. ( 24852884 )
2014
29
Gallbladder disease and cholecystectomies, active component, U.S. Armed Forces, 2004-2013. ( 24978472 )
2014
30
Gallbladder disease in an elderly patient. ( 23842824 )
2013
31
Gallbladder disease. ( 23826592 )
2013
32
Predictors of incidental gallbladder cancer in patients undergoing cholecystectomy for benign gallbladder disease. ( 22886779 )
2013
33
Surgery for acute gallbladder disease in Sweden 1989-2006--a register study. ( 23356689 )
2013
34
Ursodeoxycholic acid therapy in gallbladder disease, a story not yet completed. ( 23964136 )
2013
35
Surgical management of gallbladder disease in the very elderly: are we operating them at the right time? ( 23169310 )
2013
36
Different expression of S100A8 in malignant and benign gallbladder diseases. ( 22806545 )
2013
37
Etiology and incidence of pediatric gallbladder disease. ( 24074432 )
2013
38
Role of CEUS in the diagnosis of gallbladder disease. ( 23243646 )
2012
39
Contrast-enhanced ultrasonography in the diagnosis of gallbladder disease. ( 21940376 )
2012
40
Cholecystectomy due to symptomatic gallbladder disease after orthotopic liver transplantation: report of three cases. ( 23146515 )
2012
41
Evidence-based current surgical practice: calculous gallbladder disease. ( 22986769 )
2012
42
Single-incision versus conventional laparoscopic cholecystectomy in patients with uncomplicated gallbladder disease: a meta-analysis. ( 23238374 )
2012
43
Drospirenone- and levonorgestrel-containing oral contraceptives and the risk of gallbladder disease. ( 22325114 )
2012
44
Helicobacter pylori in gallbladder mucosa in patients with gallbladder disease. ( 22350820 )
2012
45
Epidemiology of gallbladder disease: cholelithiasis and cancer. ( 22570746 )
2012
46
Clinical characteristics and risk factors for symptomatic pediatric gallbladder disease. ( 22157135 )
2012
47
Concomitant gastroparesis negatively affects children with functional gallbladder disease. ( 22588599 )
2012
48
Acalculous gallbladder disease: the outcomes of treatment by laparoscopic cholecystectomy. ( 21477432 )
2011
49
Gallbladder disease in northwestern Ontario: the case for Canada's first rural ERCP program. ( 21453605 )
2011
50
Oral contraceptives and the risk of gallbladder disease: a comparative safety study. ( 21502354 )
2011

Variations for Gallbladder Disease

Expression for Gallbladder Disease

Search GEO for disease gene expression data for Gallbladder Disease.

Pathways for Gallbladder Disease

GO Terms for Gallbladder Disease

Cellular components related to Gallbladder Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular space GO:0005615 9.91 APOA1 APOB APOE CCK IL10 INS
2 endoplasmic reticulum lumen GO:0005788 9.71 APOA1 APOB APOE INS
3 very-low-density lipoprotein particle GO:0034361 9.5 APOA1 APOB APOE
4 high-density lipoprotein particle GO:0034364 9.46 APOA1 APOE
5 endosome lumen GO:0031904 9.43 APOB INS
6 endocytic vesicle lumen GO:0071682 9.43 APOA1 APOB APOE
7 low-density lipoprotein particle GO:0034362 9.33 APOA1 APOB APOE
8 chylomicron GO:0042627 9.13 APOA1 APOB APOE
9 intermediate-density lipoprotein particle GO:0034363 8.8 APOA1 APOB APOE

Biological processes related to Gallbladder Disease according to GeneCards Suite gene sharing:

(show all 44)
id Name GO ID Score Top Affiliating Genes
1 cellular protein metabolic process GO:0044267 9.92 APOA1 APOB APOE INS
2 response to drug GO:0042493 9.92 ABCB4 ABCG8 APOA1 IL10 UGT1A1
3 receptor-mediated endocytosis GO:0006898 9.91 APOA1 APOB APOE SOAT1
4 negative regulation of inflammatory response GO:0050728 9.82 APOA1 APOE IL10
5 lipid transport GO:0006869 9.81 ABCB4 APOA1 APOB APOE
6 retinoid metabolic process GO:0001523 9.77 APOA1 APOB APOE
7 response to organic substance GO:0010033 9.76 ABCB4 APOB IL10 UGT1A1
8 lipoprotein metabolic process GO:0042157 9.75 APOA1 APOB APOE
9 cholesterol metabolic process GO:0008203 9.73 APOA1 APOB APOE SOAT1
10 cellular response to estradiol stimulus GO:0071392 9.71 ABCB4 IL10 UGT1A1
11 response to nutrient GO:0007584 9.71 ABCG8 APOA1 CCKAR UGT1A1
12 regulation of sensory perception of pain GO:0051930 9.69 CCK IL10
13 lipid homeostasis GO:0055088 9.69 ABCB4 APOE
14 low-density lipoprotein particle clearance GO:0034383 9.69 APOB SOAT1
15 cholesterol transport GO:0030301 9.68 APOA1 APOB
16 artery morphogenesis GO:0048844 9.68 APOB APOE
17 positive regulation of nitric-oxide synthase activity GO:0051000 9.68 APOE INS
18 reverse cholesterol transport GO:0043691 9.68 APOA1 APOE
19 high-density lipoprotein particle remodeling GO:0034375 9.67 APOA1 APOE
20 high-density lipoprotein particle assembly GO:0034380 9.67 APOA1 APOE
21 low-density lipoprotein particle remodeling GO:0034374 9.67 APOB APOE
22 triglyceride homeostasis GO:0070328 9.67 APOA1 APOE GCKR
23 fatty acid homeostasis GO:0055089 9.66 APOE INS
24 phospholipid efflux GO:0033700 9.66 APOA1 APOE
25 positive regulation of lipid biosynthetic process GO:0046889 9.65 APOE INS
26 very-low-density lipoprotein particle assembly GO:0034379 9.65 APOB SOAT1
27 triglyceride catabolic process GO:0019433 9.65 APOA1 APOB APOE
28 negative regulation of heterotypic cell-cell adhesion GO:0034115 9.64 APOA1 IL10
29 positive regulation of cholesterol esterification GO:0010873 9.64 APOA1 APOE
30 high-density lipoprotein particle clearance GO:0034384 9.63 APOA1 APOE
31 chylomicron remnant clearance GO:0034382 9.62 APOB APOE
32 neuron projection regeneration GO:0031102 9.61 APOA1 APOE
33 negative regulation of cytokine secretion involved in immune response GO:0002740 9.59 APOA1 IL10
34 very-low-density lipoprotein particle clearance GO:0034447 9.58 APOB APOE
35 regulation of Cdc42 protein signal transduction GO:0032489 9.57 APOA1 APOE
36 glucocorticoid metabolic process GO:0008211 9.56 APOA1 MECP2
37 lipoprotein catabolic process GO:0042159 9.55 APOB APOE
38 steroid metabolic process GO:0008202 9.55 APOA1 APOB APOE SOAT1 UGT1A1
39 lipoprotein biosynthetic process GO:0042158 9.54 APOA1 APOB APOE
40 chylomicron assembly GO:0034378 9.5 APOA1 APOB APOE
41 chylomicron remodeling GO:0034371 9.43 APOA1 APOB APOE
42 cholesterol homeostasis GO:0042632 9.35 ABCG8 APOA1 APOB APOE SOAT1
43 cholesterol efflux GO:0033344 9.02 ABCG8 APOA1 APOB APOE SOAT1
44 lipid metabolic process GO:0006629 10.03 ABCB4 APOA1 APOB APOE SOAT1

Molecular functions related to Gallbladder Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 phospholipid binding GO:0005543 9.54 APOA1 APOB APOE
2 low-density lipoprotein particle receptor binding GO:0050750 9.43 APOB APOE
3 phospholipid transporter activity GO:0005548 9.4 ABCB4 APOA1
4 cholesterol binding GO:0015485 9.33 APOA1 APOE SOAT1
5 lipoprotein particle binding GO:0071813 9.32 APOA1 APOE
6 phosphatidylcholine-sterol O-acyltransferase activator activity GO:0060228 9.26 APOA1 APOE
7 lipid transporter activity GO:0005319 9.13 APOA1 APOB APOE
8 cholesterol transporter activity GO:0017127 8.92 ABCG8 APOA1 APOB APOE

Sources for Gallbladder Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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