MCID: GNG008
MIFTS: 40

Ganglioneuroblastoma malady

Neuronal diseases, Cancer diseases, Rare diseases categories

Aliases & Classifications for Ganglioneuroblastoma

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 48Orphanet, 61UMLS, 39NCIt, 33MeSH, 56SNOMED-CT, 62UMLS via Orphanet
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Aliases & Descriptions for Ganglioneuroblastoma:

Name: Ganglioneuroblastoma 8 10 44 48 61


Classifications:



Characteristics (Orphanet epidemiological data):

48
ganglioneuroblastoma:
Inheritance: Not applicable; Age of onset: Childhood,Infancy


External Ids:

Disease Ontology8 DOID:4163
NCIt39 C3790
MeSH33 D018305
SNOMED-CT56 69515008
Orphanet48 251877
UMLS via Orphanet62 C0206718

Summaries for Ganglioneuroblastoma

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Wikipedia:64 Ganglioneuroblastoma is a variant of neuroblastoma that is surrounded by ganglion cells. more...

MalaCards based summary: Ganglioneuroblastoma is related to neuroblastoma and paraganglioma. An important gene associated with Ganglioneuroblastoma is MYCN (v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog), and among its related pathways is Neuroscience. The compounds vanillylmandelic acid and pentylenetetrazol have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, bone and brain, and related mouse phenotypes are behavior/neurological and normal.

Related Diseases for Ganglioneuroblastoma

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Diseases related to Ganglioneuroblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 96)
idRelated DiseaseScoreTop Affiliating Genes
1neuroblastoma30.9SYP, MYCN, VIP
2paraganglioma30.2SYP, S100B
3cushing's syndrome30.1SYP, NPY
4ganglioglioma30.0S100B, SYP
5pheochromocytoma30.0VIP, MYCN, SYP, NPY
6neurofibroma30.0S100B, SYP
7adrenocortical carcinoma29.9SYP, VIP
8ganglioneuroma29.9VIP, MYCN, SYP, S100B, NPY
9cerebral primitive neuroectodermal tumor10.5MYCN
10diarrhea10.4
11hirschsprung disease 110.4VIP
12papilloma10.4MYCN
13nodular ganglioneuroblastoma10.4
14hirschsprung disease ganglioneuroblastoma10.4
15peripheral nervous system ganglioneuroblastoma10.3
16mediastinum ganglioneuroblastoma10.3
17mediastinitis10.3
18ataxia10.3
19dysembryoplastic neuroepithelial tumor10.3SYP
20glomus tumor10.3SYP
21neuronitis10.2
22adrenal gland ganglioneuroblastoma10.2
23cerebritis10.2
24sarcoma, synovial10.2S100B, MYCN
25sex cord-gonadal stromal tumor10.2NPY, S100B
26ewing sarcoma10.2S100B, MYCN
27intermixed schwannian stroma-rich ganglioneuroblastoma10.2
28stroma-dominant and stroma-poor composite ganglioneuroblastoma10.2
29schwannian stroma-rich and stroma-poor composite ganglioneuroblastoma10.2
30cervicitis10.2
31paraneoplastic syndromes10.2
32rhinitis10.1NPY, VIP
33papillary ependymoma10.1S100B, SYP
34subependymal giant cell astrocytoma10.1SYP, S100B
35olfactory neuroblastoma10.1SYP, S100B
36choroid plexus papilloma10.1S100B, SYP
37rhabdomyosarcoma10.1S100B, MYCN
38neuroblastoma 210.1
39wilms tumor10.1
40neurofibromatosis10.1
41gangliocytoma10.1
42osteomalacia10.1
43hypokalemia10.1
44phaeochromocytoma10.1
45turner syndrome10.1
46myoclonus10.1
47pineocytoma10.1S100B, SYP
48granular cell tumor10.1SYP, S100B
49hemangioblastoma10.1SYP, S100B
50pilocytic astrocytoma10.1SYP, S100B

Graphical network of the top 20 diseases related to Ganglioneuroblastoma:



Diseases related to ganglioneuroblastoma

Symptoms for Ganglioneuroblastoma

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Drugs & Therapeutics for Ganglioneuroblastoma

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Drug clinical trials:

Search ClinicalTrials for Ganglioneuroblastoma

Search NIH Clinical Center for Ganglioneuroblastoma

Genetic Tests for Ganglioneuroblastoma

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Anatomical Context for Ganglioneuroblastoma

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MalaCards organs/tissues related to Ganglioneuroblastoma:

31
Spinal cord, Bone, Brain, Adrenal gland, Bone marrow, Cerebellum, Kidney, Lung, Lymph node, Thymus, Colon, Myeloid, Pineal, Pituitary

Animal Models for Ganglioneuroblastoma or affiliated genes

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MGI Mouse Phenotypes related to Ganglioneuroblastoma:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053868.6NPY, S100B, MYCN, VIP
2MP:00028737.4NPY, S100B, SYP, MYCN, VIP

Publications for Ganglioneuroblastoma

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Articles related to Ganglioneuroblastoma:

(show top 50)    (show all 213)
idTitleAuthorsYear
1
Adult adrenal ganglioneuroblastoma: A rare case report. (25737766)
2015
2
Pediatric cerebral ganglioneuroblastoma. (25216629)
2014
3
Ventricular ganglioneuroblastoma in an adult and successful treatment with radiotherapy. (25207191)
2014
4
The neuroblastoma and ganglion components of nodular ganglioneuroblastoma are genetically similar: evidence against separate clonal origins. (25081755)
2014
5
Giant thoracoabdominal ganglioneuroblastoma in a 17-year-old patient. (24887835)
2013
6
Cerebral ganglioneuroblastoma of adult onset: two patients and a review of the literature. (22510501)
2012
7
Ganglioneuroblastoma: Case report and review of the literature. (23396255)
2011
8
Simultaneous tumors: acute myeloid leukemia infiltrating mediastinal ganglioneuroblastoma. (20973101)
2011
9
Ganglioneuroblastoma of the conus: a rare and aggressive tumor. (21150078)
2010
10
The low-affinity neurotrophin receptor, p75, is upregulated in ganglioneuroblastoma/ganglioneuroma and reduces tumorigenicity of neuroblastoma cells in vivo. (19142969)
2009
11
Nodular ganglioneuroblastoma in adults. (19680497)
2009
12
Genome analysis and gene expression profiling of neuroblastoma and ganglioneuroblastoma reveal differences between neuroblastic and Schwannian stromal cells. (16178058)
2005
13
Canine ganglioneuroblastoma in the oral mucosa. (15003480)
2004
14
Adult-type ganglioneuroblastoma in the adrenal gland treated by a laparoscopic resection: report of a case. (14513331)
2003
15
Shoulder pain in a child: a case presentation of ganglioneuroblastoma. (10754787)
2000
16
Primary pulmonary ganglioneuroblastoma: a clinicopathologic and immunohistochemical study of two cases. (9845734)
1998
17
Simultaneous adrenocortical carcinoma and ganglioneuroblastoma in a child with Turner syndrome and germline p53 mutation. (9598730)
1998
18
Ganglioneuroblastoma and ganglioneuroma in association with neurofibromatosis type I: report of three cases. (9701489)
1998
19
Adult ganglioneuroblastoma of the anterior mediastinum. (9505266)
1997
20
Cerebellin and cerebellin mRNA in the human brain, adrenal glands and the tumour tissues of adrenal tumour, ganglioneuroblastoma and neuroblastoma. (9246935)
1997
21
Central hypoventilation syndrome associated with ganglioneuroblastoma. (8555134)
1995
22
An immunohistochemical study of peripheral neuroblastoma, ganglioneuroblastoma, anaplastic ganglioglioma, schwannoma and neurofibroma in cattle. (7962722)
1994
23
Pathologic quiz case 1. Cervical ganglioneuroblastoma. (8318213)
1993
24
N-myc gene amplification/expression in localized stroma-rich neuroblastoma (ganglioneuroblastoma). (8454274)
1993
25
Isolation of chromosome-specific DNA sequences from an Alu polymerase chain reaction library to define the breakpoint in a patient with a constitutional translocation t(1;13) (q22;q12) and ganglioneuroblastoma. (1630820)
1992
26
An adrenaline-secreting ganglioneuroblastoma with elevated urinary HMMA but normal metanephrine excretion. (1489167)
1992
27
Neuropeptide Y as a plasma marker for phaeochromocytoma, ganglioneuroblastoma and neuroblastoma. (1327637)
1992
28
Intestinal ganglioneuroblastoma in a 22-week fetus. (1409156)
1992
29
Ganglioneuroblastoma and urticaria by physical agents. (2368174)
1990
30
Identification of 5-HT1A recognition sites in human ganglioneuroblastoma. (2575526)
1989
31
Bilateral adrenal ganglioneuroblastoma with neuromelanin. Clinical and pathologic observations. (3277701)
1988
32
False positive bone scan secondary to sympathectomy following resection of a ganglioneuroblastoma or affect of unilateral sympathectomy of bone scan in the pediatric patient. (3352830)
1988
33
Primary small bowel ganglioneuroblastoma and Friedreich's ataxia. (3585899)
1987
34
Cervical ganglioneuroblastoma. (3572236)
1987
35
Malignant pheochromocytoma with ganglioneuroblastoma elements in a patient with von Recklinghausen's disease. (3922614)
1985
36
The isolation and sequence analysis of vasoactive intestinal peptide from a ganglioneuroblastoma. (6092409)
1984
37
The role of surgery, radio- and chemotherapy in the treatment of neuroblastoma and ganglioneuroblastoma. (6878720)
1983
38
Extraosseous localization of 99mTc-MDP in ganglioneuroblastoma. (6214400)
1982
39
Primary pulmonary ganglioneuroblastoma in an adult: maturation, involution and the immune response. (7275023)
1981
40
Case report. Computer assisted tomographic evaluation of a ganglioneuroblastoma in an adult. (422782)
1979
41
Histopathological study of an imperfect type ganglioneuroblastoma. (462578)
1979
42
Intractable diarrhea in a boy with vasoactive intestinal peptide-producing ganglioneuroblastoma. (854377)
1977
43
Pigmented ganglioneuroblastoma: relation of melanin and lipofuscin to schwannomas and other tumors of neural crest origin. (180265)
1976
44
Bilateral adrenal ganglioneuroblastoma in a premature calf. (962741)
1976
45
Retroperitoneal ganglioneuroblastoma: a kaleidoscope of neuronal degeneration. A light and electron microscopic study. (173810)
1976
46
Ganglioneuroblastoma associated with malignant mesenchymoma. (1182658)
1975
47
Metastatic ganglioneuroblastoma: report of case and review of the literature. (4600171)
1974
48
Metastatic ganglioneuroblastoma. Ultrastructural, histochemical, and virological studies in a case. (5343392)
1969
49
Ganglioneuroblastoma: angiographic-histologic correlation. (5769305)
1969
50
Multiple tumors of the sympathetic nervous system: Report of a case showing a distinct ganglioneuroma, a neuroblastoma and a cystic calcifying ganglioneuroblastoma. (19970419)
1938

Variations for Ganglioneuroblastoma

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Expression for genes affiliated with Ganglioneuroblastoma

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Search GEO for disease gene expression data for Ganglioneuroblastoma.

Pathways for genes affiliated with Ganglioneuroblastoma

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Pathways related to Ganglioneuroblastoma according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
18.3NPY, S100B, SYP, MYCN

Compounds for genes affiliated with Ganglioneuroblastoma

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Compounds related to Ganglioneuroblastoma according to GeneCards Suite gene sharing:

(show top 50)    (show all 74)
idCompoundScoreTop Affiliating Genes
1vanillylmandelic acid44 2410.9VIP, MYCN
2pentylenetetrazol449.9S100B, NPY
3secretoneurin449.8NPY, VIP
4helospectin449.8VIP, NPY
5arginine vasotocin449.8NPY, VIP
6methoxamine44 28 1111.8NPY, VIP
7pacap 38449.8VIP, NPY
8guanethidine44 1110.8NPY, VIP
9alpha msh449.8VIP, NPY
10phentolamine44 28 1111.7VIP, NPY
11oxyntomodulin44 6010.7VIP, NPY
12trifluoroethanol44 1110.7NPY, VIP
13phosphoramidon44 1110.6NPY, VIP
14s 100449.6SYP, S100B
15reticulin449.5S100B, SYP
16mucicarmine449.5S100B, SYP
17pertussis449.4NPY, VIP
18l-amino acid449.4SYP, S100B
19sodium nitroprusside449.4NPY, S100B, VIP
20b 723449.4SYP, S100B
216-hydroxydopamine449.1VIP, NPY
22etoposide44 50 60 1112.1SYP, S100B, MYCN
23formaldehyde44 2410.0SYP, S100B, NPY
24streptozotocin449.0NPY, SYP
25haloperidol44 50 28 1 1113.0VIP, NPY, SYP
265-hydroxytryptamine449.0NPY, SYP, VIP
27lactate449.0NPY, S100B, MYCN, VIP
28histamine44 28 2410.8NPY, VIP, SYP
29potassium44 24 1110.8VIP, S100B, SYP
30gtp44 289.7S100B, VIP, SYP
31dbc-amp448.7SYP, S100B, VIP, MYCN
32paraffin448.7S100B, NPY, MYCN, SYP
33creatinine448.7NPY, S100B, SYP
34vegf448.6SYP, S100B, VIP, MYCN
35choline44 24 1110.6VIP, NPY, S100B, SYP
36acth448.6NPY, S100B, SYP, VIP
37gaba448.6NPY, SYP, VIP, S100B
38norepinephrine44 24 1110.6S100B, SYP, VIP, NPY
39acetylcholine44 50 28 24 1112.6VIP, NPY, SYP, S100B
40forskolin44 50 1110.6S100B, SYP, NPY, VIP
41glutamine448.6S100B, NPY, VIP, SYP
42cyclic amp44 249.6S100B, SYP, VIP, NPY
43retinoic acid44 249.5NPY, MYCN, SYP, S100B
44testosterone44 60 24 1111.5SYP, NPY, S100B, VIP
45glutamate448.5SYP, VIP, S100B, NPY
46estrogen448.4NPY, VIP, SYP, S100B
47catecholamine448.2SYP, VIP, S100B, MYCN, NPY
48dopamine44 28 24 1111.2NPY, S100B, SYP, MYCN, VIP
49nitric oxide44 24 1110.2S100B, SYP, NPY, VIP, MYCN
50tyrosine448.1MYCN, NPY, S100B, SYP, VIP

GO Terms for genes affiliated with Ganglioneuroblastoma

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Biological processes related to Ganglioneuroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of cell shapeGO:00083609.4S100B, WASF3
2learning or memoryGO:00076119.2S100B, VIP
3regulation of neuronal synaptic plasticityGO:00481689.1S100B, SYP

Molecular functions related to Ganglioneuroblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1neuropeptide hormone activityGO:00051849.4NPY, VIP

Sources for Ganglioneuroblastoma

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2CDC
12ExPASy
13FDA
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet