MCID: GSG001
MIFTS: 48

Gas Gangrene malady

Categories: Infectious diseases, Skin diseases, Muscle diseases

Aliases & Classifications for Gas Gangrene

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Aliases & Descriptions for Gas Gangrene:

Name: Gas Gangrene 32 10 47 12 36 65
Myonecrosis 10 65
 
Gas Bacillus Infection or Gangrene 10
Gas Bacillus Infection 10

Classifications:



External Ids:

Disease Ontology10 DOID:9159
ICD1027 A48.0
ICD9CM29 040.0
MeSH36 D005738
UMLS65 C0017105, C0235957

Summaries for Gas Gangrene

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Disease Ontology:10 A commensal bacterial infectious disease that results in infection, located in muscle tissue, has material basis in Clostridium perfringens, which produce gas that becomes trapped in the infected tissue. Gas gangrene usually develops after injuries or surgery. The infection has symptom large blisters, has symptom pain in the infected area, has symptom myonecrosis, has symptom gas production, and has symptom sepsis.

MalaCards based summary: Gas Gangrene, also known as myonecrosis, is related to coronary thrombosis and postpartum depression, and has symptoms including large blisters, pain in the infected area and myonecrosis. An important gene associated with Gas Gangrene is HSPG2 (Heparan Sulfate Proteoglycan 2), and among its related pathways are Muscular Dystrophies and Dystrophin-Glycoprotein Complex and Antiarrhythmic Pathway, Pharmacodynamics. Affiliated tissues include muscle tissue, breast and skin, and related mouse phenotypes are cardiovascular system and muscle.

Wikipedia:68 Gas gangrene (also known as clostridial myonecrosis and myonecrosis) is a bacterial infection that... more...

Related Diseases for Gas Gangrene

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Graphical network of the top 20 diseases related to Gas Gangrene:



Diseases related to gas gangrene

Symptoms for Gas Gangrene

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Symptoms:

 10
  • large blisters
  • pain in the infected area
  • myonecrosis
  • gas production
  • sepsis

Drugs & Therapeutics for Gas Gangrene

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Drugs for Gas Gangrene (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
GlyburideapprovedPhase 1, Phase 210710238-21-83488
Synonyms:
1-((P-(2-(5-chloro-O-Anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-((p-(2-(5-Chloro-o-anisamido)ethyl)phenyl)sulfonyl)-3-cyclohexylurea
1-(P-(2-(5-chloro-2-Methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
1-(p-(2-(5-Chloro-2-methoxybenzamido)ethyl)benzenesulfonyl)-3-cyclohexylurea
10238-21-8
5-Chloro-N-[4-(cyclohexylureidosulfonyl)phenethyl]-2-methoxybenzamide
5-chloro-N-(2-(4-((((Cyclohexylamino)carbonyl)amino)sulfonyl)phenyl)ethyl)-2-methoxybenzamide
5-chloro-N-[2-[4-(cyclohexylcarbamoylsulfamoyl)phenyl]ethyl]-2-methoxybenzamide
AB00051949
AC1L1G1Q
AC1Q44V7
AKOS001487495
Abbenclamide
Adiab
Apo-Glibenclamide
Azuglucon
BIDD:GT0239
BPBio1_000344
BRD-K36927236-001-06-0
BRN 2230085
BSPBio_000312
BSPBio_001351
BSPBio_003053
Bastiverit
Benclamin
Betanase
Betanese 5
Bio-0156
Bio1_000076
Bio1_000565
Bio1_001054
Bio2_000071
Bio2_000551
C07022
C23H28ClN3O5S
CAS-10238-21-8
CBiol_001790
CHEBI:5441
CHEMBL472
CID3488
CPD000058229
Calabren
Cytagon
D00336
D005905
DB01016
Daonil
Debtan
Dia-basan
Diabeta
Diabeta (TN)
Diabiphage
Dibelet
DivK1c_000481
Duraglucon
EINECS 233-570-6
EU-0100499
Euclamin
Euglucan
Euglucon
Euglucon 5
Euglucon N
Euglykon
G 0639
G0639_SIAL
G0639_SIGMA
G2539_SIAL
GBN 5
Gen-Glybe
Gewaglucon
Gilemal
Glamide
Glibadone
Gliban
Gliben
Gliben-Puren N
Glibenbeta
Glibenclamid AL
Glibenclamid Basics
Glibenclamid Fabra
Glibenclamid Genericon
Glibenclamid Heumann
Glibenclamid Riker M
Glibenclamid Riker M.
Glibenclamid-Cophar
Glibenclamid-Ratiopharm
Glibenclamida
Glibenclamida [INN-Spanish]
Glibenclamide
Glibenclamide (JP15/INN)
Glibenclamidum
Glibenclamidum [INN-Latin]
Glibenil
Glibens
Glibesyn
Glibet
Glibetic
Glibil
Gliboral
Glicem
Glidiabet
Glimel
Glimide
Glimidstata
Glisulin
Glitisol
Glubate
Gluben
Gluco-Tablimen
Glucobene
Glucohexal
Glucolon
Glucomid
Glucoremed
Glucoven
Glyben
Glybenclamide
Glybenzcyclamide
Glyburide
Glyburide (USP)
Glyburide (micronized)
Glyburide [USAN]
 
Glycolande
Glycomin
Glynase
Glynase (TN)
HB 419
HB 420
HB-419
HB-420
HB419
HB420
HMS1361D13
HMS1568P14
HMS1791D13
HMS1922L08
HMS1989D13
HMS2089L06
HMS2093P04
HMS501I03
Hemi-Daonil
Hexaglucon
Humedia
I06-0716
IDI1_000481
IDI1_033821
KBio1_000481
KBio2_000071
KBio2_000730
KBio2_002639
KBio2_003298
KBio2_005207
KBio2_005866
KBio3_000141
KBio3_000142
KBio3_002273
KBioGR_000071
KBioGR_001897
KBioSS_000071
KBioSS_000730
LS-159295
Lederglib
Libanil
Lisaglucon
Lopac-G-0639
Lopac0_000499
MLS000069721
MLS001077262
Malix
Maninil
Med-Glionil
Melix
Micronase
Micronase (TN)
Micronized glyburide
Miglucan
MolPort-000-784-850
N-(4-(2-(5-Chloro-2-methoxybenzamido)ethyl)phenylsulfonyl)-N'-cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)-ethyl]benzene-sulfonyl-N -cyclohexylurea
N-p-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl-N'-cyclohexylurea
NCGC00015467-01
NCGC00015467-02
NCGC00015467-06
NCGC00015467-16
NCGC00016689-01
NCGC00023447-02
NCGC00023447-04
NCGC00023447-05
NCGC00023447-06
NCGC00023447-07
NCGC00023447-08
NCGC00023447-09
NCGC00023447-10
NCGC00023447-11
NCGC00023447-12
NINDS_000481
Nadib
Neogluconin
Norglicem 5
Normoglucon
Novo-Glyburide
Oprea1_764617
Orabetic
Pira
Praeciglucon
PresTab
Prestwick0_000316
Prestwick1_000316
Prestwick2_000316
Prestwick3_000316
Prestwick_569
Probes1_000431
Probes2_000378
Prodiabet
Renabetic
S1716_Selleck
SAM002564212
SMR000058229
SPBio_001831
SPBio_002531
SPECTRUM2300229
SR-01000000196-5
STK362992
Semi-Daonil
Semi-Euglucon
Semi-Gliben-Puren N
Semi-daonil
Spectrum2_001816
Spectrum3_001327
Spectrum4_001199
Spectrum5_001631
Spectrum_000250
Sugril
Suraben
Tiabet
Tocris-0911
U 26452
U-26452
UNII-SX6K58TVWC
UPCMLD-DP006
UPCMLD-DP006:001
UR 606
Yuglucon
ZINC00537805
glibenclamide
glyburide
2
ImidaclopridPhase 1, Phase 2139105827-78-986418
Synonyms:
(e)-imidacloprid
(z)-imidacloprid
1-((6-Chloro-3-pyridyl)methyl)-N-nitro-2-imidazolidinimine
1-(2-Chloro-5-pyridylmethyl)-2-(nitroimino)imidazolidine
1-[(6-Chloro-3-pyridinyl)methyl]-4,5-dihydro-N-nitro-1H-imidazol-2-amine, 9CI
Admire
Advantage
Advantage flea adulticide
Bayer brand of imidacloprid
 
Confidor
Confidor 200 SL
Confidor SL
Gaucho
Imidacloprid (old RN)
Imidacloprid [iso]
Merit
Merit (insecticide)
Premise 75
Provado
3Hypoglycemic AgentsPhase 1, Phase 24503
4Immunologic FactorsPhase 218483
5Rho(D) Immune GlobulinPhase 2206
6Immunoglobulins, IntravenousPhase 2211
7Immunoglobulin GPhase 2146
8ImmunoglobulinsPhase 24477
9AntibodiesPhase 24477
10
Carbon monoxidePhase 1102281
Synonyms:
 
CO
Carbon monoxide

Interventional clinical trials:

idNameStatusNCT IDPhase
1Glyburide Advantage in Malignant Edema and Stroke PilotCompletedNCT01268683Phase 1, Phase 2
2Glyburide Advantage in Malignant Edema and Stroke - Remedy PharmaceuticalsActive, not recruitingNCT01794182Phase 2
3Immunoglobulin for Necrotizing Soft Tissue Infections: a Randomised Controlled TrialActive, not recruitingNCT02111161Phase 2
4A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic ChildrenCompletedNCT00670891Phase 1
5Biomarkers in Patients With Flesh-eating Bacterial InfectionsCompletedNCT02180906
6Modulation of Biomarkers in Patients With Flesh-eating Bacterial Infections After With Hyperbaric Oxygen TreatmentRecruitingNCT02501382
7Hyperbaric Oxygen Therapy RegistryEnrolling by invitationNCT02483650

Search NIH Clinical Center for Gas Gangrene

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Gas Gangrene cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Gas Gangrene:
Peripheral blood-derived hematopoietic stem cells for leg gangrene
Embryonic/Adult Cultured Cells Related to Gas Gangrene:
Peripheral blood-derived hematopoietic stem cells


Cochrane evidence based reviews: gas gangrene

Genetic Tests for Gas Gangrene

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Anatomical Context for Gas Gangrene

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MalaCards organs/tissues related to Gas Gangrene:

33
Breast, Skin, Prostate, Brain, Bone, Lung, Neutrophil

FMA organs/tissues related to Gas Gangrene:

16
Muscle tissue

Animal Models for Gas Gangrene or affiliated genes

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MGI Mouse Phenotypes related to Gas Gangrene:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053857.1CASQ2, DMD, HSPG2, ITGA2B, MB, TNNI3
2MP:00053697.0CASQ1, CASQ2, CPE, DMD, HSPG2, MB
3MP:00053786.9CASQ1, CASQ2, CPE, DMD, HSPG2, MB
4MP:00053766.8CASQ2, CPE, DMD, HSPG2, ITGA2B, MB

Publications for Gas Gangrene

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Articles related to Gas Gangrene:

(show top 50)    (show all 520)
idTitleAuthorsYear
1
Cullin3-BTB interface: a novel target for stapled peptides. (25848797)
2015
2
White matter fractional anisotropy over two time points in early onset schizophrenia and adolescent cannabis use disorder: A naturalistic diffusion tensor imaging study. (25779033)
2015
3
Hypertriglyceridemia in extremely low birth weight infants receiving lipid emulsions. (26410437)
2015
4
A phosphotyrosine switch determines the antitumor activity of ERI^. (24960160)
2014
5
Molluscum contagiosum infection on a congenital intermediate melanocytic naevus. (25183021)
2014
6
As little as needed: the extraordinary case of a mild recessive osteopetrosis owing to a novel splicing hypomorphic mutation in the TCIRG1 gene. (24535816)
2014
7
Association of Kaposi's sarcoma-associated herpesvirus (KSHV) with bladder cancer in Croatian patients. (23959475)
2013
8
Association between TP53 R249S mutation and polymorphisms in TP53 intron 1 in hepatocellular carcinoma. (23836507)
2013
9
Optimal Dosing of Melphalan As High-Dose Therapy Before Autologous Hematopoietic Stem Cell Transplantation in Myeloma Patients With Solitary Kidney: A Case Series. (24378319)
2013
10
The central oscillatory network of orthostatic tremor. (23926026)
2013
11
Flecainide and antiarrhythmic effects in a mouse model of catecholaminergic polymorphic ventricular tachycardia. (22867967)
2012
12
Anti-neutrophil cytoplasmic antibody-associated systemic vasculitis: nature or nurture? (24020350)
2012
13
New treatment strategy for granulomatous epulis: intralesional injection of propranolol. (22133559)
2012
14
Low levels of Stat5a protein in breast cancer are associated with tumor progression and unfavorable clinical outcomes. (23036105)
2012
15
Is silent myocardial infarction more common in women with type 2 diabetes than in men? (22446034)
2012
16
Role of rhinitis in laryngitis: another dimension of the unified airway. (21922973)
2011
17
Hangover Predicts Residual Alcohol Effects on Psychomotor Vigilance the Morning After Intoxication. (21643431)
2010
18
Marked reduction of tremor in essential tremor after putaminal infarct. (20581413)
2010
19
Endocervicoscopy: a new technique for the diagnostic work-up of cervical intraepithelial neoplasia allowing a tailored excisional therapy in young fertile women. (20451182)
2010
20
The paradox of intracranial hypotension responding well to CSF drainage. (19863649)
2009
21
Genetic defect in Chinese azoospermic patients and their relationship with reproductive hormones]. (20017309)
2009
22
Characterization and regulation of bv8 in human blood cells. (19336519)
2009
23
Corneal epithelial-like transdifferentiation of hair follicle stem cells is mediated by pax6 and beta-catenin/Lef-1. (19393751)
2009
24
Giant ossifying fibroma complicated by mucocele of sphenoid sinus--case report. (19105117)
2008
25
Mice lacking the signaling molecule CalDAG-GEFI represent a model for leukocyte adhesion deficiency type III. (17492052)
2007
26
Unsaturated fatty acids suppress the expression of the ATP-binding cassette transporter G1 (ABCG1) and ABCA1 genes via an LXR/RXR responsive element. (16730733)
2007
27
Black, white and shades of grey: SUNCT or short-lasting chronic paroxysmal hemicrania? (17119794)
2006
28
Evaluation of sexual function in young men with spina bifida and myelomeningocele using the International Index of Erectile Function. (16504267)
2006
29
Evidence-based emergency medicine/rational clinical examination abstract. The clinical diagnosis of streptococcal pharyngitis. (15988434)
2005
30
Effect of anti-immunoglobulin E on nasal inflammation in patients with seasonal allergic rhinoconjunctivitis. (15248853)
2004
31
Abnormal lens shape on CT in a patient with Aniridia. (14762425)
2004
32
The aryl hydrocarbon receptor antagonist, 3'methoxy-4'nitroflavone, attenuates 2,3,7,8-tetrachlorodibenzo-p-dioxin-dependent regulation of growth factor signaling and apoptosis in the MCF-10A cell line. (12668121)
2003
33
Gender differences in the levels of bisphenol A metabolites in urine. (14637157)
2003
34
Clinical features of late-onset pseudotumor cerebri fulfilling the modified dandy criteria. (11937898)
2002
35
Leptin in the regulation of energy balance]. (11928535)
2002
36
Recombinant activated factor VII (rFVIIa) acutely normalizes prothrombin time in patients with cirrhosis during bleeding from oesophageal varices. (11589383)
2001
37
Localization of chromogranin, synaptophysin, serotonin, and CXCR2 in neuroendocrine cells of the minor vestibular glands: an immunohistochemical study. (10542945)
1999
38
A complex program of striatal gene expression induced by dopaminergic stimulation. (9651213)
1998
39
Primary structure of CD52. (7890742)
1995
40
Analysis of estrogen and progesterone receptors on preoperative fine-needle aspirates. (7749144)
1995
41
Childhood vaccination against chickenpox: an analysis of benefits and costs. (8201469)
1994
42
Acute gastric dilatation in two black and white colobus monkeys. (8230180)
1993
43
Activin-A inhibits progesterone production by macaque luteal cells in culture. (1517365)
1992
44
Nucleotide sequence of cDNA covering the complete coding part of the human vimentin gene. (2251132)
1990
45
Methodological aspects of aldehyde dehydrogenase assay by spectrophotometric technique. (2222842)
1990
46
Brain potentials reveal covert facial recognition in prosopagnosia. (2771029)
1989
47
Unusual venous thrombosis associated with protein C deficiency. (3346957)
1988
48
Leads from the MMWR. Acute hemorrhagic conjunctivitis caused by coxsackievirus A24--Caribbean. (3586222)
1987
49
Effects of pyridoxine deficiency and dietary cholesterol supplementation in the chick on plasma protein-bound iodine, glutamic-oxalacetic transaminase activity, and 14-C-acetate incorporation into cholesterol. (4164049)
1966
50
Surgical management of benign intraductal papilloma of the breast. (14911043)
1952

Variations for Gas Gangrene

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Expression for genes affiliated with Gas Gangrene

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Search GEO for disease gene expression data for Gas Gangrene.

Pathways for genes affiliated with Gas Gangrene

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GO Terms for genes affiliated with Gas Gangrene

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Biological processes related to Gas Gangrene according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of heart rateGO:00020279.8CASQ2, DMD
2regulation of skeletal muscle contraction by regulation of release of sequestered calcium ionGO:00148099.8CASQ1, DMD
3striated muscle contractionGO:00069419.7CASQ2, TNNI3
4regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ionGO:00108819.5CASQ2, DMD
5cardiac muscle contractionGO:00600488.7CASQ2, DMD, TNNI3, TNNT2

Sources for Gas Gangrene

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet