MCID: GST008
MIFTS: 30

Gastric Adenosquamous Carcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Adenosquamous Carcinoma

MalaCards integrated aliases for Gastric Adenosquamous Carcinoma:

Name: Gastric Adenosquamous Carcinoma 12 14 69
Adenosquamous Carcinoma of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5635
NCIt 46 C5474
UMLS 69 C1333761

Summaries for Gastric Adenosquamous Carcinoma

MalaCards based summary : Gastric Adenosquamous Carcinoma, also known as adenosquamous carcinoma of stomach, is related to adenosquamous carcinoma and spinal cord astrocytoma, and has symptoms including dyspepsia and abdominal pain. An important gene associated with Gastric Adenosquamous Carcinoma is TFRC (Transferrin Receptor), and among its related pathways/superpathways are MicroRNAs in cancer and Cell adhesion_ECM remodeling. Related phenotypes are cardiovascular system and cellular

Related Diseases for Gastric Adenosquamous Carcinoma

Diseases related to Gastric Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 41)
# Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 10.4
2 spinal cord astrocytoma 10.2 CD44 PROM1
3 cholangiolocellular carcinoma 10.2 CDKN2A PROM1
4 brain germinoma 10.2 CD44 PROM1
5 breast giant fibroadenoma 10.1 CD44 CDKN2A
6 juvenile pilocytic astrocytoma 10.1 CD44 CDKN2A
7 in situ pulmonary adenocarcinoma 10.1 EGFR PROM1
8 malignant peritoneal mesothelioma 10.0 CDKN2A EGFR
9 anaplastic oligodendroglioma 10.0 CDKN2A EGFR
10 squamous cell carcinoma of the larynx 10.0 CDKN2A EGFR
11 cervical adenosquamous carcinoma 10.0 CDKN2A EGFR
12 oropharynx cancer 10.0 CDKN2A EGFR
13 peritoneal mesothelioma 10.0 CDKN2A EGFR
14 basaloid squamous cell carcinoma 10.0 CDKN2A EGFR
15 vulva cancer 10.0 CDKN2A EGFR
16 pre-malignant neoplasm 10.0 CDKN2A EGFR
17 mucinous adenocarcinoma 10.0 CDKN2A EGFR
18 penile cancer 9.9 CDKN2A EGFR
19 in situ carcinoma 9.9 CDKN2A EGFR
20 chordoma 9.9 CDKN2A EGFR
21 pharynx cancer 9.9 CDKN2A EGFR
22 grade iii astrocytoma 9.9 CDKN2A EGFR
23 cervical adenocarcinoma 9.8 CDKN2A EGFR
24 brain cancer 9.8 CD44 EGFR TFRC
25 cervical squamous cell carcinoma 9.8 CDKN2A EGFR
26 small intestinal adenocarcinoma 9.8 CD44 EGFR PROM1
27 endometrial adenocarcinoma 9.8 CDKN2A EGFR
28 ovarian cancer 1 9.7 CD44 EGFR
29 female reproductive organ cancer 9.7 CD44 CDKN2A EGFR
30 reproductive organ cancer 9.7 CD44 CDKN2A EGFR
31 oral squamous cell carcinoma 9.7 CD44 CDKN2A EGFR
32 larynx cancer 9.7 CD44 CDKN2A EGFR
33 squamous cell carcinoma, head and neck 9.7 CD44 CDKN2A EGFR
34 glioblastoma multiforme 9.7 CD44 CDKN2A EGFR
35 squamous cell carcinoma 9.5 CD44 CDKN2A EGFR
36 oral cancer 9.5 CDKN2A EGFR
37 pancreas adenocarcinoma 9.4 CD44 CDKN2A EGFR PROM1
38 pancreatic ductal adenocarcinoma 9.4 CD44 CDKN2A EGFR PROM1
39 gastrointestinal system cancer 9.4 CD44 CDKN2A EGFR PROM1
40 cell type cancer 9.4 CD44 CDKN2A EGFR PROM1
41 esophageal cancer 9.4 CD44 CDKN2A EGFR

Graphical network of the top 20 diseases related to Gastric Adenosquamous Carcinoma:



Diseases related to Gastric Adenosquamous Carcinoma

Symptoms & Phenotypes for Gastric Adenosquamous Carcinoma

UMLS symptoms related to Gastric Adenosquamous Carcinoma:


dyspepsia, abdominal pain

MGI Mouse Phenotypes related to Gastric Adenosquamous Carcinoma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.88 EGFR ITGA6 PROM1 CD44 TFRC CDKN2A
2 cellular MP:0005384 9.85 CDKN2A EGFR ITGA6 PROM1 CD44 TFRC
3 digestive/alimentary MP:0005381 9.72 EGFR ITGA6 CD44 TFRC CDKN2A
4 integument MP:0010771 9.65 EGFR ITGA6 CD44 TFRC CDKN2A
5 neoplasm MP:0002006 9.55 EGFR ITGA6 PROM1 CD44 CDKN2A
6 nervous system MP:0003631 9.43 CDKN2A EGFR ITGA6 PROM1 CD44 TFRC
7 vision/eye MP:0005391 9.02 EGFR ITGA6 PROM1 CD44 CDKN2A

Drugs & Therapeutics for Gastric Adenosquamous Carcinoma

Search Clinical Trials , NIH Clinical Center for Gastric Adenosquamous Carcinoma

Genetic Tests for Gastric Adenosquamous Carcinoma

Anatomical Context for Gastric Adenosquamous Carcinoma

Publications for Gastric Adenosquamous Carcinoma

Articles related to Gastric Adenosquamous Carcinoma:

(show all 12)
# Title Authors Year
1
Clinicopathological features and prognosis of gastric adenosquamous carcinoma. ( 28676632 )
2017
2
Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor: a case of a rare malignancy. ( 28493097 )
2017
3
Clinicopathological characteristics, diagnosis, treatment, and outcomes of primary gastric adenosquamous carcinoma. ( 25889482 )
2015
4
Fatal submucosal invasive gastric adenosquamous carcinoma detected at surveillance after gastric endoscopic submucosal dissection. ( 25892891 )
2015
5
Durable response of human epidermal growth factor receptor-2-positive gastric adenosquamous carcinoma to trastuzumab-based chemotherapy. ( 24803897 )
2014
6
Fever as a first manifestation of advanced gastric adenosquamous carcinoma: a case report. ( 25110448 )
2014
7
Primary gastric adenosquamous carcinoma in an Indian male. ( 24441236 )
2013
8
A patient with gastric adenosquamous carcinoma with intraperitoneal free cancer cells who remained recurrence-free with postoperative S-1 chemotherapy. ( 23154717 )
2012
9
Absence of CD71 transferrin receptor characterizes human gastric adenosquamous carcinoma stem cells. ( 21523522 )
2012
10
Primary gastric adenosquamous carcinoma in a Caucasian woman: a case report. ( 21034475 )
2010
11
Weekly paclitaxel therapy is effective for gastric adenosquamous carcinoma: a case report. ( 19579645 )
2009
12
Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor. ( 16086120 )
2005

Variations for Gastric Adenosquamous Carcinoma

Expression for Gastric Adenosquamous Carcinoma

Search GEO for disease gene expression data for Gastric Adenosquamous Carcinoma.

Pathways for Gastric Adenosquamous Carcinoma

Pathways related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.91 CD44 CDKN2A EGFR
2 11.15 CD44 EGFR
3 11.03 CDKN2A EGFR
4 10.79 CD44 ITGA6 TFRC
5 10.65 EGFR ITGA6
6 10.43 EGFR PROM1

GO Terms for Gastric Adenosquamous Carcinoma

Cellular components related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apical plasma membrane GO:0016324 9.33 CD44 EGFR PROM1
2 clathrin-coated vesicle membrane GO:0030665 9.26 EGFR TFRC
3 basolateral plasma membrane GO:0016323 9.13 EGFR ITGA6 TFRC
4 cell surface GO:0009986 9.02 CD44 EGFR ITGA6 PROM1 TFRC

Biological processes related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular response to drug GO:0035690 9.26 EGFR TFRC
2 positive regulation of phosphorylation GO:0042327 9.16 EGFR ITGA6
3 positive regulation of bone resorption GO:0045780 8.96 EGFR TFRC
4 cell-cell adhesion GO:0098609 8.8 CD44 EGFR ITGA6

Molecular functions related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cadherin binding GO:0045296 8.8 EGFR ITGA6 PROM1

Sources for Gastric Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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