MCID: GST008
MIFTS: 29

Gastric Adenosquamous Carcinoma malady

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Adenosquamous Carcinoma

Aliases & Descriptions for Gastric Adenosquamous Carcinoma:

Name: Gastric Adenosquamous Carcinoma 12 14 69
Adenosquamous Carcinoma of Stomach 12

Classifications:



External Ids:

Disease Ontology 12 DOID:5635
NCIt 47 C5474
UMLS 69 C1333761

Summaries for Gastric Adenosquamous Carcinoma

MalaCards based summary : Gastric Adenosquamous Carcinoma, also known as adenosquamous carcinoma of stomach, is related to adenosquamous carcinoma and testicular fibroma, and has symptoms including abdominal pain and dyspepsia. An important gene associated with Gastric Adenosquamous Carcinoma is TFRC (Transferrin Receptor), and among its related pathways/superpathways are MicroRNAs in cancer and Cell adhesion_ECM remodeling. Related phenotypes are cardiovascular system and cellular

Related Diseases for Gastric Adenosquamous Carcinoma

Diseases related to Gastric Adenosquamous Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 34)
id Related Disease Score Top Affiliating Genes
1 adenosquamous carcinoma 10.3
2 testicular fibroma 10.1 CDKN2A PROM1
3 central nervous system sarcoma 10.1 CD44 PROM1
4 cutaneous adenocystic carcinoma 10.1 CD44 PROM1
5 pancreatic invasive mucinous cystadenocarcinoma 10.1 CD44 CDKN2A
6 immunodeficiency due to a classical component pathway complement deficiency 10.1 CDKN2A EGFR
7 tricuspid valve prolapse 10.0 CDKN2A EGFR
8 intermediate malignant teratoma 10.0 CDKN2A EGFR
9 chronic monocytic leukemia 10.0 CDKN2A EGFR
10 tumor of exocrine pancreas 10.0 CDKN2A EGFR
11 thymus squamous cell carcinoma 10.0 CDKN2A EGFR
12 secondary hyperparathyroidism of renal origin 10.0 CDKN2A EGFR
13 myxedema 10.0 CDKN2A EGFR
14 allergic contact dermatitis 10.0 CDKN2A EGFR
15 estrogen-receptor positive breast cancer 10.0 CDKN2A EGFR
16 pityriasis rosea 10.0 CDKN2A EGFR
17 nodular goiter 9.9 CD44 EGFR TFRC
18 sengers syndrome 9.9 CDKN2A EGFR
19 spastic diplegia infantile type 9.9 CD44 EGFR PROM1
20 interstitial lung disease 9.9 CDKN2A EGFR
21 connective tissue benign neoplasm 9.9 CDKN2A EGFR
22 pearson syndrome 9.9 CDKN2A EGFR PROM1
23 hepatic flexure cancer 9.9 CD44 CDKN2A EGFR
24 in situ pulmonary adenocarcinoma 9.9 CD44 CDKN2A EGFR
25 bardet-biedl syndrome 9.9 CD44 CDKN2A EGFR
26 pyomyositis 9.9 CDKN2A EGFR
27 grade iii astrocytoma 9.9 CD44 CDKN2A EGFR
28 hypogonadotropic hypogonadism 20 with or without anosmia 9.9 CD44 CDKN2A EGFR
29 ladd syndrome 9.9 CD44 CDKN2A EGFR
30 ocular melanoma 9.9 CD44 CDKN2A EGFR
31 maxillary sinus cholesteatoma 9.9 CD44 CDKN2A
32 malignant pleural solitary fibrous tumor 9.7 CD44 CDKN2A EGFR PROM1
33 proctitis 9.7 CD44 CDKN2A EGFR PROM1
34 urethral villous adenoma 8.9 CAGE1 CD44 CDKN2A EGFR FNDC5 ITGA6

Graphical network of the top 20 diseases related to Gastric Adenosquamous Carcinoma:



Diseases related to Gastric Adenosquamous Carcinoma

Symptoms & Phenotypes for Gastric Adenosquamous Carcinoma

UMLS symptoms related to Gastric Adenosquamous Carcinoma:


abdominal pain, dyspepsia

MGI Mouse Phenotypes related to Gastric Adenosquamous Carcinoma:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.88 CD44 CDKN2A EGFR ITGA6 PROM1 TFRC
2 cellular MP:0005384 9.85 CD44 CDKN2A EGFR ITGA6 PROM1 TFRC
3 digestive/alimentary MP:0005381 9.72 CD44 CDKN2A EGFR ITGA6 TFRC
4 integument MP:0010771 9.65 CD44 CDKN2A EGFR ITGA6 TFRC
5 neoplasm MP:0002006 9.55 CD44 CDKN2A EGFR ITGA6 PROM1
6 nervous system MP:0003631 9.43 CD44 CDKN2A EGFR ITGA6 PROM1 TFRC
7 vision/eye MP:0005391 9.02 CD44 CDKN2A EGFR ITGA6 PROM1

Drugs & Therapeutics for Gastric Adenosquamous Carcinoma

Interventional clinical trials:


id Name Status NCT ID Phase
1 MAGE-A4ᶜ¹º³²T for Multi-Tumor Recruiting NCT03132922 Phase 1

Search NIH Clinical Center for Gastric Adenosquamous Carcinoma

Genetic Tests for Gastric Adenosquamous Carcinoma

Anatomical Context for Gastric Adenosquamous Carcinoma

Publications for Gastric Adenosquamous Carcinoma

Articles related to Gastric Adenosquamous Carcinoma:

id Title Authors Year
1
Fatal submucosal invasive gastric adenosquamous carcinoma detected at surveillance after gastric endoscopic submucosal dissection. ( 25892891 )
2015
2
Clinicopathological characteristics, diagnosis, treatment, and outcomes of primary gastric adenosquamous carcinoma. ( 25889482 )
2015
3
Fever as a first manifestation of advanced gastric adenosquamous carcinoma: a case report. ( 25110448 )
2014
4
Durable response of human epidermal growth factor receptor-2-positive gastric adenosquamous carcinoma to trastuzumab-based chemotherapy. ( 24803897 )
2014
5
Primary gastric adenosquamous carcinoma in an Indian male. ( 24441236 )
2013
6
Absence of CD71 transferrin receptor characterizes human gastric adenosquamous carcinoma stem cells. ( 21523522 )
2012
7
A patient with gastric adenosquamous carcinoma with intraperitoneal free cancer cells who remained recurrence-free with postoperative S-1 chemotherapy. ( 23154717 )
2012
8
Primary gastric adenosquamous carcinoma in a Caucasian woman: a case report. ( 21034475 )
2010
9
Weekly paclitaxel therapy is effective for gastric adenosquamous carcinoma: a case report. ( 19579645 )
2009
10
Gastric adenosquamous carcinoma producing granulocyte-colony stimulating factor. ( 16086120 )
2005

Variations for Gastric Adenosquamous Carcinoma

Expression for Gastric Adenosquamous Carcinoma

Search GEO for disease gene expression data for Gastric Adenosquamous Carcinoma.

Pathways for Gastric Adenosquamous Carcinoma

Pathways related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.91 CD44 CDKN2A EGFR
2 11.15 CD44 EGFR
3 11.03 CDKN2A EGFR
4 10.79 CD44 ITGA6 TFRC
5 10.65 EGFR ITGA6
6 10.43 EGFR PROM1

GO Terms for Gastric Adenosquamous Carcinoma

Cellular components related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 clathrin-coated vesicle membrane GO:0030665 9.16 EGFR TFRC
2 basolateral plasma membrane GO:0016323 9.13 EGFR ITGA6 TFRC
3 cell surface GO:0009986 9.02 CD44 EGFR ITGA6 PROM1 TFRC

Biological processes related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cellular response to drug GO:0035690 9.26 EGFR TFRC
2 positive regulation of phosphorylation GO:0042327 9.16 EGFR ITGA6
3 positive regulation of bone resorption GO:0045780 8.96 EGFR TFRC
4 single organismal cell-cell adhesion GO:0016337 8.8 CD44 EGFR ITGA6

Molecular functions related to Gastric Adenosquamous Carcinoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 glycoprotein binding GO:0001948 8.96 EGFR TFRC
2 cadherin binding GO:0045296 8.8 EGFR ITGA6 PROM1

Sources for Gastric Adenosquamous Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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