MCID: GST020
MIFTS: 32

Gastric Antral Vascular Ectasia malady

Rare diseases, Gastrointestinal diseases, Cardiovascular diseases categories

Summaries for Gastric Antral Vascular Ectasia

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NIH Rare Diseases:41 Watermelon stomach is a condition in which the lining of the stomach bleeds, causing it to look like the characteristic stripes of a watermelon when viewed by endoscopy. although it can develop in men and women of all ages, watermelon stomach is most commonly observed in older women (over age 70 years). signs and symptoms of watermelon stomach include blood in stool, hematemesis (vomiting blood) and anemia. the exact cause of watermelon stomach is unknown; however, it is often diagnosed in people with other chronic (long-term) conditions such as cirrhosis (scarring of the liver and poor liver function), autoimmune disease, systemic sclerosis, and crest syndrome. treatment consists of surgery and/or medications to stop or control the bleeding. last updated: 12/6/2014

MalaCards based summary: Gastric Antral Vascular Ectasia, also known as watermelon stomach, is related to portal hypertension and hematopoietic stem cell transplantation. An important gene associated with Gastric Antral Vascular Ectasia is SST (somatostatin). The compounds bromocriptine and octreotide have been mentioned in the context of this disorder. Affiliated tissues include liver and myeloid, and related mouse phenotype homeostasis/metabolism.

Wikipedia:63 Gastric antral vascular ectasia (GAVE) is an uncommon cause of chronic gastrointestinal bleeding or iron... more...

Aliases & Classifications for Gastric Antral Vascular Ectasia

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Gastric Antral Vascular Ectasia, Aliases & Descriptions:

Name: Gastric Antral Vascular Ectasia 9 41 11
Watermelon Stomach 9 41
 
Gave 41


Classifications:



External Ids:

Disease Ontology9 DOID:2493
MeSH33 D020252
SNOMED-CT55 412795008, 43935004
NCIt38 C84724

Related Diseases for Gastric Antral Vascular Ectasia

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Diseases related to Gastric Antral Vascular Ectasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 51)
idRelated DiseaseScoreTop Affiliating Genes
1portal hypertension10.9
2hematopoietic stem cell transplantation10.5
3liver disease10.5
4angiodysplasia10.5
5bacteremia10.4
6deficiency anemia10.4
7hemangioma10.4
8leukemia10.4
9liver cirrhosis10.4
10primary biliary cirrhosis10.4
11iron deficiency anemia10.4
12protein-losing enteropathy10.4
13proctitis10.4
14capillary hemangioma10.4
15myeloid leukemia10.4
16scleroderma10.4
17chronic graft versus host disease10.4
18gastric outlet obstruction10.4
19radiation proctitis10.4
20systemic lupus erythematosus10.2
21dengue hemorrhagic fever10.2
22gastritis10.2
23lupus erythematosus10.2
24peritonitis10.2
25stomach disease10.2
26uremia10.2
27hemorrhagic fever10.2
28transcobalamin ii deficiency10.1
29spherocytosis, type 110.0
30cartilage-hair hypoplasia10.0
31smith-lemli-opitz syndrome10.0
32marfan syndrome10.0
33ichthyosis, x-linked10.0
34agammaglobulinemia 110.0
35androgen insensitivity10.0
36caudal regression syndrome10.0
37hyperlipidemia, familial combined10.0
38hiv-110.0
39ciliary dyskinesia, primary, 1, with or without situs inversus10.0
40progressive external ophthalmoplegia, autosomal recessive10.0
41von willebrand disease, platelet-type10.0
42cataract10.0
43polycystic ovary syndrome10.0
44bestiality10.0
45congenital hypothyroidism10.0
46sick sinus syndrome10.0
47corneal dystrophy10.0
48hypothyroidism10.0
49prostatitis10.0
50turner syndrome10.0

Graphical network of the top 20 diseases related to Gastric Antral Vascular Ectasia:



Diseases related to gastric antral vascular ectasia

Symptoms for Gastric Antral Vascular Ectasia

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Drugs & Therapeutics for Gastric Antral Vascular Ectasia

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Drug clinical trials:

Search ClinicalTrials for Gastric Antral Vascular Ectasia

Search NIH Clinical Center for Gastric Antral Vascular Ectasia

Genetic Tests for Gastric Antral Vascular Ectasia

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Anatomical Context for Gastric Antral Vascular Ectasia

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MalaCards organs/tissues related to Gastric Antral Vascular Ectasia:

31
Liver, Myeloid

Animal Models for Gastric Antral Vascular Ectasia or affiliated genes

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MGI Mouse Phenotypes related to Gastric Antral Vascular Ectasia:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053768.8SST, ELOVL2, EPO

Publications for Gastric Antral Vascular Ectasia

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Articles related to Gastric Antral Vascular Ectasia:

(show top 50)    (show all 136)
idTitleAuthorsYear
1
Gastric Antral Vascular Ectasia (GAVE): An Overlooked Diagnosis. (25772970)
2015
2
Gastric antral vascular ectasia: a prospective study of treatment with endoscopic band ligation. (25650636)
2015
3
Dasatinib-induced gastric antral vascular ectasia in a patient with acute lymphoblastic leukaemia. (25855138)
2015
4
Gastrointestinal: radiofrequency ablation in the management of refractory gastric antral vascular ectasia. (24750200)
2014
5
Prevalence, Correlates and Outcomes of Gastric Antral Vascular Ectasia in Systemic Sclerosis: A EUSTAR Case-control Study. (24293584)
2014
6
Gastric antral vascular ectasia unresponsive to endoscopic treatment requiring antrectomy. (25240797)
2014
7
Review article: the management of portal hypertensive gastropathy and gastric antral vascular ectasia in cirrhosis. (24889902)
2014
8
Gastric antral vascular ectasia: a rare manifestation for gastrointestinal bleeding in left ventricular assist device patients-an initial report. (24821465)
2014
9
Gastric antral vascular ectasia (GAVE) in two non-cirrhotic patients involved large area of stomach: case report and literature review. (24478930)
2013
10
Diagnosis and management of gastric antral vascular ectasia. (23330048)
2013
11
Massive gastric antral vascular ectasia successfully treated by endoscopic band ligation as the initial therapy. (23515642)
2013
12
Gastric antral vascular ectasia: case report and review of the literature. (23262190)
2013
13
Radiofrequency ablation for refractory gastric antral vascular ectasia (with video). (23660565)
2013
14
Band ligation of gastric antral vascular ectasia is a safe and effective endoscopic treatment. (23808945)
2013
15
External-beam radiotherapy: A realistic therapeutic option for the gastric antral vascular ectasia. (24377029)
2012
16
Endoscopic band ligation versus argon plasma coagulation for gastric antral vascular ectasia associated with liver diseases. (22725108)
2012
17
The management of portal hypertensive gastropathy and gastric antral vascular ectasia. (21095166)
2011
18
Clinical images: Gastric antral vascular ectasia in systemic sclerosis. (20039398)
2010
19
A novel endoscopic ablation of gastric antral vascular ectasia. (21160630)
2010
20
Gastric antral vascular ectasia (GAVE) in a non-cirrhotic patients with diabetes: case report and possible pathophysiological mechanism. (22736555)
2010
21
Pharmacotherapy for gastric antral vascular ectasia: dramatic response to tranexamic acid. (19559844)
2009
22
Endoscopic band ligation for the treatment of gastric antral vascular ectasia. (19410053)
2009
23
Improvement of severe systemic sclerosis-associated gastric antral vascular ectasia following immunosuppressive treatment with intravenous cyclophosphamide. (19605670)
2009
24
Endoscopic argon plasma coagulation for the treatment of gastric antral vascular ectasia-related bleeding in patients with liver cirrhosis. (19329853)
2009
25
Gastric antral vascular ectasia (GAVE) associated with systemic sclerosis. (18612935)
2008
26
Endoscopic mucosal resection for recurrent gastric antral vascular ectasia. (18690599)
2008
27
Hyperplastic gastric polyps after argon plasma coagulation treatment of gastric antral vascular ectasia (GAVE). (18273773)
2007
28
Gastric antral vascular ectasia successfully controlled by argon plasma coagulation. (17767344)
2007
29
Efficacy of neodymium:YAG laser therapy for gastric antral vascular ectasia (GAVE) following hematopoietic cell transplant. (16284614)
2006
30
A case report of gastric antral vascular ectasia (watermelon stomach) as a rare cause of gastrointestinal bleeding. (16547859)
2005
31
Review article: current therapeutic options for gastric antral vascular ectasia. (12869075)
2003
32
Clinical features and treatment of hematopoietic stem cell transplantation-associated gastric antral vascular ectasia. (12900779)
2003
33
Cure of gastric antral vascular ectasia by liver transplantation despite persistent portal hypertension: a clue for pathogenesis. (12149766)
2002
34
Gastric antral vascular ectasia as the only presenting feature of limited cutaneous systemic sclerosis. (11907373)
2002
35
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome. (11709525)
2001
36
Gastric antral vascular ectasia--a cause of refractory anaemia in systemic sclerosis. (11837631)
2001
37
Gastric antral vascular ectasia and its relation with portal hypertension. (10733318)
2000
38
Treatment of chronic bleeding from gastric antral vascular ectasia (GAVE) with estrogen-progesterone in cirrhotic patients: an open pilot study. (10520843)
1999
39
Histopathologic changes are not specific for diagnosis of gastric antral vascular ectasia (GAVE) syndrome: a review of the pathogenesis and a comparative image analysis morphometric study of GAVE syndrome and gastric hyperplastic polyps. (9576573)
1998
40
Gastric antral vascular ectasia in a patient on hemodialysis improved with CAPD. (9147554)
1996
41
Gastric antral vascular ectasia: a case report and review of the literature. (8965161)
1996
42
Bleeding from gastric antral vascular ectasia in marrow transplant patients. (8885337)
1996
43
A case of gastric antral vascular ectasia--increase of neuroendocrine cells in the antrum. (7647906)
1995
44
Gastric antral vascular ectasia. (1842378)
1991
45
Successful control of bleeding from gastric antral vascular ectasia (watermelon stomach) by laser photocoagulation. (1991643)
1991
46
Two cases of gastric antral vascular ectasia--response to medical treatment. (1765249)
1991
47
Successful treatment of two patients with gastric antral vascular ectasia 'watermelon stomach' using endoscopic Nd-YAG laser therapy. (1953533)
1991
48
Gastric antral vascular ectasia and primary biliary cirrhosis. (3265915)
1988
49
Diffuse gastric antral vascular ectasia: cause of chronic gastrointestinal blood loss. (3500039)
1987
50
Gastric antral vascular ectasia: the watermelon stomach. (6332757)
1984

Variations for Gastric Antral Vascular Ectasia

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Expression for genes affiliated with Gastric Antral Vascular Ectasia

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Search GEO for disease gene expression data for Gastric Antral Vascular Ectasia.

Pathways for genes affiliated with Gastric Antral Vascular Ectasia

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Compounds for genes affiliated with Gastric Antral Vascular Ectasia

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Compounds related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

idCompoundScoreTop Affiliating Genes
1bromocriptine43 28 1211.6EPO, SST
2octreotide43 59 28 1212.5SST, EPO
3carboplatin43 49 1211.5SST, EPO
4hydrocortisone43 2 59 1212.5EPO, SST
5caffeine43 28 2 49 24 1214.4EPO, SST
6gnrh439.4SST, EPO
7rapamycin439.3EPO, SST
8vegf439.3EPO, SST
9lactate439.2SST, EPO
10testosterone43 59 24 1212.0EPO, SST

GO Terms for genes affiliated with Gastric Antral Vascular Ectasia

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Molecular functions related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.3SST, EPO

Products for genes affiliated with Gastric Antral Vascular Ectasia

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Sources for Gastric Antral Vascular Ectasia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet