MCID: GST020
MIFTS: 32

Gastric Antral Vascular Ectasia malady

Categories: Rare diseases, Cardiovascular diseases, Gastrointestinal diseases

Aliases & Classifications for Gastric Antral Vascular Ectasia

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Aliases & Descriptions for Gastric Antral Vascular Ectasia:

Name: Gastric Antral Vascular Ectasia 11 47 38 13
Watermelon Stomach 11 47
 
Gave 47

Classifications:



External Ids:

Disease Ontology11 DOID:2493
MeSH38 D020252
SNOMED-CT61 412795008, 43935004
NCIt44 C84724

Summaries for Gastric Antral Vascular Ectasia

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Wikipedia:70 Gastric antral vascular ectasia (GAVE) is an uncommon cause of chronic gastrointestinal bleeding or iron... more...

MalaCards based summary: Gastric Antral Vascular Ectasia, also known as watermelon stomach, is related to transcobalamin ii deficiency and caudal regression syndrome. An important gene associated with Gastric Antral Vascular Ectasia is SST (Somatostatin), and among its related pathways is Salivary secretion. Affiliated tissues include liver, myeloid and kidney.

Related Diseases for Gastric Antral Vascular Ectasia

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Diseases related to Gastric Antral Vascular Ectasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 58)
idRelated DiseaseScoreTop Affiliating Genes
1transcobalamin ii deficiency10.8
2caudal regression syndrome10.7
3hyperlipidemia, familial combined10.7
4spherocytosis, type 110.7
5cartilage-hair hypoplasia10.7
6smith-lemli-opitz syndrome10.7
7agammaglobulinemia 110.7
8marfan syndrome10.7
9ichthyosis, x-linked10.7
10ciliary dyskinesia, primary, 1, with or without situs inversus10.7
11progressive external ophthalmoplegia, autosomal recessive 110.7
12von willebrand disease, platelet-type10.7
13portal hypertension10.5
14hematopoietic stem cell transplantation10.1
15leukemia10.1
16liver disease10.1
17angiodysplasia10.1
18pancreatic cystadenocarcinoma10.0ATP4A, SST
19parathyroid gland disease10.0ATP4A, SST
20tooth ankylosis10.0ATP4A, BRD4
21ring staphyloma10.0ATP4A, SST
22central nervous system germ cell tumor10.0BRD4, SST
23intracortical osteogenic sarcoma9.9ATP4A, SST
24bacteremia9.9
25deficiency anemia9.9
26hemangioma9.9
27liver cirrhosis9.9
28primary biliary cirrhosis9.9
29protein-losing enteropathy9.9
30iron deficiency anemia9.9
31capillary hemangioma9.9
32proctitis9.9
33duodenitis9.9
34myeloid leukemia9.9
35chronic graft versus host disease9.9
36radiation proctitis9.9
37gemistocytic astrocytoma9.9ATP4A, SST
38systemic lupus erythematosus9.8
39dengue hemorrhagic fever9.8
40crest syndrome9.8
41limited scleroderma9.8
42gastritis9.8
43uremia9.8
44stomach disease9.8
45peritonitis9.8
46lupus erythematosus9.8
47diffuse cutaneous systemic sclerosis9.8
48hemorrhagic fever9.8
49bubonic plague9.8CTC1, SST
50eosinophilic gastritis9.8ATP4A, SST

Graphical network of the top 20 diseases related to Gastric Antral Vascular Ectasia:



Diseases related to gastric antral vascular ectasia

Symptoms for Gastric Antral Vascular Ectasia

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Drugs & Therapeutics for Gastric Antral Vascular Ectasia

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Drugs for Gastric Antral Vascular Ectasia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Proton pump inhibitorsPhase 2, Phase 31080
Synonyms:
 
PPIs
2
IronapprovedPhase 211237439-89-623925
Synonyms:
02583_FLUKA
12310_ALDRICH
12310_RIEDEL
129048-51-7
14067-02-8
161135-39-3
190454-13-8
195161-83-2
199281-22-6
209309_ALDRICH
209309_SIAL
255637_ALDRICH
266213_ALDRICH
266256_ALDRICH
267945_ALDRICH
267953_ALDRICH
26Fe
338141_ALDRICH
356808_ALDRICH
356824_ALDRICH
356832_ALDRICH
39344-71-3
3ZhP
413054_ALDRICH
443783-52-6
44890_ALDRICH
44890_FLUKA
675141-17-0
70884-35-4
73135-38-3
7439-89-6
8011-79-8
8053-60-9
AC1L2N38
ATW 230
ATW 432
Ancor B
Ancor en 80/150
Armco iron
Atomel 28
Atomel 300M200
Atomel 500M
Atomel 95
Atomiron 44MR
Atomiron 5M
Atomiron AFP 25
Atomiron AFP 5
C00023
C3518_SIAL
C3518_SIGMA
CCRIS 1580
CHEBI:18248
CID23925
Carbonyl iron
Copy Powder CS 105-175
D007501
DB01592
DSP 1000
DSP 128B
DSP 135
DSP 135C
DSP 138
Diseases (animal), iron overload
Diseases, iron overload
EF 1000
EF 250
EFV 200/300
EFV 250
EFV 250/400
EINECS 231-096-4
 
Ed-In-Sol
Eisen
Electrolytic iron
F 60 (metal)
FE
FT 3 (element)
Fe
Fe-40
Fe1+
Feronate
Ferretts
Ferro-Caps
Ferro-Time
Ferrousal
Ferrovac E
Ferrum
Ferrum metallicum
GS 6
HF 2 (element)
HL (iron)
HQ (metal)
HS (iron)
HS 4849
HSDB 604
Hemocyte
Hierro
Hoeganaes ATW 230
Hoeganaes EH
IRMM524A_FLUKA
IRMM524B_FLUKA
IRON
Iron (Fe)
Iron (Fe1+)
Iron ion (Fe+)
Iron ion(1+)
Iron monocation
Iron powder
Iron standard for AAS
Iron(1+)
Iron(1+) ion
Iron(III) nitrate solution
Iron, carbonyl
Iron, electrolytic
Iron, elemental
Iron, ion (Fe1+)
Iron, ion (Fe1+) (8CI,9CI)
Iron, reduced
LOHA
LS-3196
MolPort-003-925-001
NC 100
PZh-1M3
PZh-2
PZh1M1
PZh2M
PZh2M1
PZh2M2
PZh3
PZh3M
PZh4M
PZhO
Reduced iron
Remko
SUY-B 2
Siderol
UNII-E1UOL152H7
Vitedyn-Slo
Yieronia
fer
ferrous iron
hierro
3Angiogenesis InhibitorsPhase 24143
4Angiogenesis Modulating AgentsPhase 24072
5Immunosuppressive AgentsPhase 212770
6Anti-Infective AgentsPhase 221402
7Anti-Bacterial AgentsPhase 210884
8
Simvastatinapproved51079902-63-954454
Synonyms:
(+)-Simvastatin
(1S,3R,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl 2,2-dimethylbutanoate
2,2-Dimethylbutanoic acid (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8aR)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
2,2-Dimethylbutyric acid, 8-ester with (4R,6R)-6-(2-((1S,2S,6R,8S,8ar)-1,2,6,7,8,8a-hexahydro-8-hydroxy-2,6-dimethyl-1-naphthyl)ethyl)tetrahydro-4-hydroxy-2H-pyran-2-one
79902-63-9
AC-1530
AC1L1H1F
AKOS005111006
ARONIS24119
BCBcMAP01_000007
BIDD:GT0769
BPBio1_001001
BRD-K22134346-001-05-8
BRN 4768037
BSPBio_000909
BSPBio_002337
Bio-0672
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,*aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-(2-((2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)ethyl)-1-naphthalenyl ester
Butanoic acid, 2,2-dimethyl-, (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl ester
C25H38O5
CCRIS 7558
CHEBI:9150
CHEMBL1064
CID54454
CPD000718785
Cholestat
Coledis
Colemin
Corolin
D00434
D019821
DRG-0320
Denan
DivK1c_006991
Eucor
HMS1570N11
HMS1922H13
HMS2089D12
HMS2093E06
HSDB 7208
InChI=1/C25H38O5/c1-6-25(4,5)24(28)30-21-12-15(2)11-17-8-7-16(3)20(23(17)21)10-9-19-13-18(26)14-22(27)29-19/h7-8,11,15-16,18-21,23,26H,6,9-10,12-14H2,1-5H3/t15-,16-,18+,19+,20-,21-,23-/m0/s1
KBio1_001935
KBio2_002197
KBio2_004765
KBio2_007333
KBio3_001557
KBioGR_001244
KBioSS_002197
KS-1113
Kolestevan
L 644128-000U
LS-46264
Labistatin
Lipex
Lipinorm
Liponorm
Lipovas
Lodales
MK 0733
MK 733
MK-0733
MK-733
MK733
MLS001304029
MLS001333077
MLS001333078
 
MLS002154038
Medipo
Modutrol
MolPort-002-507-345
MolPort-002-885-862
NCGC00017324-01
NCGC00017324-02
NCGC00017324-03
Nivelipol
Nor-Vastina
Pantok
Pepstatin
Prestwick0_000865
Prestwick1_000865
Prestwick2_000865
Prestwick3_000865
Prestwick_171
Rechol
Rendapid
S1792_Selleck
S6196_SIGMA
SAM002589969
SMR000718785
SPBio_001881
SPBio_002830
SPECTRUM1504236
STK801938
Simcor
Simovil
Simvast CR
Simvastatin
Simvastatin & Primycin
Simvastatin (JAN/USP/INN)
Simvastatin [USAN:INN:BAN]
Simvastatin [Usan:Ban:Inn]
Simvastatin lactone
Simvastatin, Compactin
Simvastatina
Simvastatina [Spanish]
Simvastatine
Simvastatine [French]
Simvastatinum
Simvastatinum [Latin]
Simvotin
Sinvacor
Sinvascor
Sivastin
SpecPlus_000895
Spectrum2_001671
Spectrum3_000669
Spectrum4_000632
Spectrum5_001428
Spectrum_001717
Statin
Synvinolin
TNP00259
UNII-AGG2FN16EV
Valemia
Vasotenal
Velostatin
Vytorin
ZINC03780893
Zocor
Zocor (TN)
Zocor, Simlup, Simcard, Simvacor, Simvoget, Zorced, Simvastatin
Zocord
[(1S,3R,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-3,7-dimethyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] 2,2-dimethylbutanoate
butanoic acid, 2,2-dimethyl-,1,2,3,7,8,8a-hexahydro-3,7-dimethyl-8-[2-(tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl)-ethyl]-1-naphthalenyl ester, [1S-[1 alpha,3 alpha,7 beta,8 beta(2S*,4S*),-8a beta
nchembio790-comp16
simvastatin
9
Carvedilolapproved, investigational16372956-09-32585
Synonyms:
(+-)-1-(Carbazol-4-yloxy)-3-((2-(O-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-(Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+-)-1-Carbazol-4-yloxy)-3-((2-(o-methoxyphenoxy)ethyl)amino)-2-propanol
(+/-)-1-(Carbazol-4-yloxy)-3-[[2-(o-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-Carbazol-4-yloxy)-3-[[2-(2-methoxyphenoxy)ethyl]amino]-2-propanol
1-(9H-carbazol-4-yloxy)-3-[(2-{[2-(methyloxy)phenyl]oxy}ethyl)amino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol
1-(9H-carbazol-4-yloxy)-3-{[2-(2-methoxyphenoxy)ethyl]amino}propan-2-ol
107741-96-8
72956-09-3
AB1004830
AC-1641
AC1L1E0B
Artist
Artist (TN)
Atlana Pharma brand of carvedilol
BM 14190
BM-14-190
BM-14.190
BM-14190
BRD-A10977446-001-04-8
BRD-A10977446-045-01-1
Bio-0014
C043211
C06875
C2260
C24H26N2O4
CHEBI:3441
CHEMBL723
CID2585
CPD000449280
Carvedilol
Carvedilol (JAN/USAN/INN)
Carvedilol [USAN:INN:BAN:JAN]
Carvedilolum
Carvedilolum [Latin]
Coreg
Coreg (TN)
Coreg CR
Coropres
Coropress
D00255
DB01136
DQ 2466
DQ-2466
Dibloc
 
Dilatrend
EG-P042
Eucardic
GlaxoSmithKline brand of carvedilol
HMS2051N03
HMS2089B09
HMS2093E12
HSDB 7044
I06-0064
I06-1477
KBio2_002145
KBio2_004713
KBio2_007281
KBio3_002323
KBioGR_001252
KBioSS_002145
Kredex
L001243
LS-121875
Lakeside brand of carvedilol
MLS000758299
MLS000759508
MLS001424092
MolPort-003-666-814
NCGC00167832-01
NCGC00167832-02
NCGC00167832-03
Querto
Roche brand of carvedilol
SAM001246736
SAM001247021
SK&F-105517
SKF 105517
SMR000449280
SPBio_001885
STK621453
Spectrum2_001673
Spectrum3_001182
Spectrum4_000636
Spectrum5_001436
Spectrum_001665
TL8005080
UNII-0K47UL67F2
carvedilol
carvedilol, (+-)-isomer
carvedilol, (R)-isomer
carvedilol, (S)-isomer
carvedilol, 14C-labeled
10Hypolipidemic Agents2721
11Hydroxymethylglutaryl-CoA Reductase Inhibitors1956
12Vasodilator Agents3438
13Neurotransmitter Agents17734
14Lipid Regulating Agents2702
15Adrenergic Antagonists1535
16Adrenergic alpha-1 Receptor Antagonists470
17Adrenergic Agents5140
18Adrenergic alpha-Antagonists727
19Adrenergic beta-Antagonists1154
20Antihypertensive Agents4095
21Anticholesteremic Agents1983
22Antimetabolites11774

Interventional clinical trials:

idNameStatusNCT IDPhase
1Endoscopic Band Ligation Versus Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical TrialCompletedNCT01601639Phase 3
2Cyrotherapy vs. APC in GAVECompletedNCT00587405Phase 2, Phase 3
3Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular MalformationCompletedNCT00964496Phase 2
4To Compare the Efficacy and Safety of Carvedilol With or Without Simvastatin in Patients With Portal Hypertension and Esophageal Varices.RecruitingNCT02465645

Search NIH Clinical Center for Gastric Antral Vascular Ectasia


Cochrane evidence based reviews: gastric antral vascular ectasia

Genetic Tests for Gastric Antral Vascular Ectasia

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Anatomical Context for Gastric Antral Vascular Ectasia

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MalaCards organs/tissues related to Gastric Antral Vascular Ectasia:

35
Liver, Myeloid, Kidney

Animal Models for Gastric Antral Vascular Ectasia or affiliated genes

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Publications for Gastric Antral Vascular Ectasia

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Articles related to Gastric Antral Vascular Ectasia:

(show top 50)    (show all 160)
idTitleAuthorsYear
1
Vascular-targeted photodynamic therapy of gastric antral vascular ectasia (GAVE). (27871022)
2017
2
Hemorrhage from Extra-Antral Gastric Antral Vascular Ectasia in a Patient with Duodenal Heterotopic Gastric Mucosa. (27830096)
2016
3
Gastric Antral Vascular Ectasia (GAVE): An Overlooked Diagnosis. (25772970)
2015
4
Portal hypertensive gastropathy and gastric antral vascular ectasia. (26376475)
2015
5
Gastric antral vascular ectasia: a prospective study of treatment with endoscopic band ligation. (25650636)
2015
6
Refractory gastric antral vascular ectasia: a new endoscopic approach. (26592837)
2015
7
Patients with Gastric Antral Vascular Ectasia (GAVE) Are at a Higher Risk of Gastrointestinal Bleeding in the Absence of Cirrhosis. (26807380)
2015
8
Radiofrequency ablation therapy - the grave for GAVE (gastric antral vascular ectasia)? (26135653)
2015
9
Development of hyperplastic polyps following argon plasma coagulation of gastric antral vascular ectasia. (26283860)
2015
10
Gastric antral vascular ectasia: the evolution of therapeutic modalities. (26135263)
2014
11
Prevalence, Correlates and Outcomes of Gastric Antral Vascular Ectasia in Systemic Sclerosis: A EUSTAR Case-control Study. (24293584)
2014
12
Gastric antral vascular ectasia unresponsive to endoscopic treatment requiring antrectomy. (25240797)
2014
13
Successful treatment of refractory gastric antral vascular ectasia by distal gastrectomy: A case report. (25320549)
2014
14
Watermelon stomach: gastric antral vascular ectasia. (25475404)
2014
15
Bacteremia and sepsis after radiofrequency ablation of gastric antral vascular ectasia. (24721631)
2014
16
Gastric Antral Vascular Ectasia. (26259325)
2014
17
Gastric antral vascular ectasia (GAVE) in two non-cirrhotic patients involved large area of stomach: case report and literature review. (24478930)
2013
18
Gastric antral vascular ectasia: case report and review of the literature. (23262190)
2013
19
External-beam radiotherapy: A realistic therapeutic option for the gastric antral vascular ectasia. (24377029)
2012
20
Endoscopic band ligation versus argon plasma coagulation for gastric antral vascular ectasia associated with liver diseases. (22725108)
2012
21
Gastric antral vascular ectasia with aortic stenosis: Heydes syndrome. (23603627)
2012
22
Long-term effect of argon plasma coagulation (APC) in the treatment of gastric antral vascular ectasia (GAVE). (21429455)
2011
23
Gastric antral vascular ectasia unmasked by alprostadil for digital ulceration in scleroderma. (21459962)
2011
24
Computed virtual chromoendoscopy - enhanced videocapsule endoscopy is of potential benefit in gastric antral vascular ectasia syndrome refractory to endoscopic treatment. (21961101)
2011
25
Clinical images: Gastric antral vascular ectasia in systemic sclerosis. (20039398)
2010
26
A novel endoscopic ablation of gastric antral vascular ectasia. (21160630)
2010
27
Laparoscopic surgical treatment for refractory gastric antral vascular ectasia: a case report and review. (19851250)
2009
28
Argon photocoagulation in the treatment of gastric antral vascular ectasia and radiation proctitis. (20011731)
2009
29
Endoscopic mucosal resection for recurrent gastric antral vascular ectasia. (18690599)
2008
30
Gastric antral vascular ectasia successfully controlled by argon plasma coagulation. (17767344)
2007
31
Gastric antral vascular ectasia (GAVE) associated with systemic sclerosis: relapse after endoscopic treatment by argon plasma coagulation. (17379994)
2007
32
Gastric antral vascular ectasia (GAVE) syndrome. (15839460)
2004
33
Clinical features and treatment of hematopoietic stem cell transplantation-associated gastric antral vascular ectasia. (12900779)
2003
34
Cure of gastric antral vascular ectasia by liver transplantation despite persistent portal hypertension: a clue for pathogenesis. (12149766)
2002
35
Gastric antral vascular ectasia as the only presenting feature of limited cutaneous systemic sclerosis. (11907373)
2002
36
Portal hypertensive gastropathy and gastric antral vascular ectasia (GAVE) syndrome. (11709525)
2001
37
Gastric antral vascular ectasia--a cause of refractory anaemia in systemic sclerosis. (11837631)
2001
38
Histopathologic changes are not specific for diagnosis of gastric antral vascular ectasia (GAVE) syndrome: a review of the pathogenesis and a comparative image analysis morphometric study of GAVE syndrome and gastric hyperplastic polyps. (9576573)
1998
39
Gastric antral vascular ectasia (the watermelon stomach): a brief case report. (9638461)
1998
40
Gastric antral vascular ectasia in a patient on hemodialysis improved with CAPD. (9147554)
1996
41
Gastric antral vascular ectasia: a case report and review of the literature. (8965161)
1996
42
Bleeding from gastric antral vascular ectasia in marrow transplant patients. (8885337)
1996
43
Long-term corticosteroid therapy for gastric antral vascular ectasia. (8792729)
1996
44
Antral motility in patients with cirrhosis with or without gastric antral vascular ectasia. (7489933)
1995
45
Gastric antral vascular ectasia: maintenance treatment with oestrogen-progesterone. (1612493)
1992
46
Gastric antral vascular ectasia. (1842378)
1991
47
Successful control of bleeding from gastric antral vascular ectasia (watermelon stomach) by laser photocoagulation. (1991643)
1991
48
Gastric antral vascular ectasia associated with gastric carcinoma. (2039004)
1991
49
Endoscopic biopsy is diagnostic in gastric antral vascular ectasia. The "watermelon stomach". (2721320)
1989
50
Diffuse gastric antral vascular ectasia: cause of chronic gastrointestinal blood loss. (3500039)
1987

Variations for Gastric Antral Vascular Ectasia

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Expression for genes affiliated with Gastric Antral Vascular Ectasia

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Search GEO for disease gene expression data for Gastric Antral Vascular Ectasia.

Pathways for genes affiliated with Gastric Antral Vascular Ectasia

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Pathways related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.5ATP4A, SST

GO Terms for genes affiliated with Gastric Antral Vascular Ectasia

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Biological processes related to Gastric Antral Vascular Ectasia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1response to nutrientGO:00075849.4OXCT1, SST
2cellular response to DNA damage stimulusGO:00069749.3BRD4, CTC1

Sources for Gastric Antral Vascular Ectasia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet