MCID: GST060
MIFTS: 47

Gastric Cancer, Somatic malady

Categories: Genetic diseases (common), Gastrointestinal diseases, Cancer diseases

Aliases & Classifications for Gastric Cancer, Somatic

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Aliases & Descriptions for Gastric Cancer, Somatic:

Name: Gastric Cancer, Somatic 52 24 12 35
Malignant Neoplasm of Stomach 68
Gastric Cancer Intestinal 70
Stomach Carcinoma 68
 
Gastric Cancer 70
Stomach Cancer 70
Gasc 70

Characteristics:

HPO:

64
gastric cancer, somatic:
Inheritance: somatic mutation

Classifications:



External Ids:

OMIM52 613659
MeSH39 D013274

Summaries for Gastric Cancer, Somatic

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UniProtKB/Swiss-Prot:70 Gastric cancer: A malignant disease which starts in the stomach, can spread to the esophagus or the small intestine, and can extend through the stomach wall to nearby lymph nodes and organs. It also can metastasize to other parts of the body. The term gastric cancer or gastric carcinoma refers to adenocarcinoma of the stomach that accounts for most of all gastric malignant tumors. Two main histologic types are recognized, diffuse type and intestinal type carcinomas. Diffuse tumors are poorly differentiated infiltrating lesions, resulting in thickening of the stomach. In contrast, intestinal tumors are usually exophytic, often ulcerating, and associated with intestinal metaplasia of the stomach, most often observed in sporadic disease.

MalaCards based summary: Gastric Cancer, Somatic, also known as malignant neoplasm of stomach, is related to gastric cancer risk after h. pylori infection and familial stomach cancer, and has symptoms including stomach cancer, abdominal pain and constipation. An important gene associated with Gastric Cancer, Somatic is MUTYH (MutY DNA Glycosylase), and among its related pathways are Angiogenesis (WikiPathways) and G-protein signaling_K-RAS regulation pathway. Affiliated tissues include colon, small intestine and lymph node, and related mouse phenotypes are Decreased viability and craniofacial.

OMIM:52 In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several... (613659) more...

Related Diseases for Gastric Cancer, Somatic

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Diseases related to Gastric Cancer, Somatic via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 63)
idRelated DiseaseScoreTop Affiliating Genes
1gastric cancer risk after h. pylori infection32.0CDH1, KRAS
2familial stomach cancer12.0
3acquired amegakaryocytic thrombocytopenia10.4APC, MUTYH
4complex lethal osteochondrodysplasia10.3CDH1, PIK3CA
5colver steer godman syndrome10.3APC, CDH1, MUTYH
6migraine with aura10.3KRAS, MUTYH
7desmoid disease, hereditary10.2APC, CDH1, MUTYH
8myelophthisic anemia10.2APC, PIK3CA
9lateral sinus thrombosis10.2CDH1, KRAS
10tumor predisposition syndrome10.2APC, CDH1, MUTYH
11malignant hyperthermia susceptibility type 210.2KRAS, PIK3CA
12epidermal nevus, somatic10.2KRAS, PIK3CA
13intrahepatic cholangiocarcinoma10.2KRAS, MUTYH
14trachea adenoid cystic carcinoma10.1KRAS, PIK3CA
15hemangioma of lung10.1CDH1, KRAS
16gastrointestinal neuroendocrine tumor10.1CDH1, KRAS, MUTYH
17periapical granuloma10.1CDH1, KRAS, MUTYH
18pregnancy adenoma10.1CDH1, ERBB2
19large intestine adenoma10.1APC, KRAS
20diffuse intrinsic pontine glioma10.1CDH1, ERBB2
21gastric squamous cell carcinoma10.1CDH1, ERBB2
22pyoderma10.1KRAS, PIK3CA
23malignant hyperthermia susceptibility10.1APC, KRAS, MUTYH
24hereditary essential tremor 510.0APC, KRAS, MUTYH
25arrhythmogenic right ventricular cardiomyopathy10.0APC, KRAS, MUTYH
26glomerulosclerosis, focal segmental, 710.0APC, MUTYH
27breast malignant phyllodes tumor10.0CDH1, ERBB2
28serous cystadenocarcinoma10.0CDH1, ERBB2
29nasal cavity adenocarcinoma9.9CDH1, FGFR2, KRAS
30vaginal adenosarcoma9.9ERBB2, PIK3CA
31retinitis9.9ERBB2, PIK3CA
32gyrate atrophy of choroid and retina with or without ornithinemia9.9ERBB2, FGFR2
33rectum mucinous adenocarcinoma9.8ERBB2, KRAS
34ductal carcinoma in situ9.8CDH1, ERBB2
35ovarian small cell carcinoma9.8ERBB2, PIK3CA
36vibratory urticaria9.8ERBB2, KRAS
37gastric cancer9.8
38zimmermann-laband syndrome 29.7CDH1, ERBB2, PIK3CA
39hartnup disorder9.7CDH1, ERBB2, KRAS
40paroxysmal nocturnal hemoglobinuria9.7CDH1, ERBB2, KRAS
41brown-vialetto-van laere syndrome9.7CDH1, ERBB2, KRAS
42anus disease9.7CDH1, ERBB2, KRAS
43hidrocystoma9.7APC, KRAS, MUTYH, PIK3CA
44stroma-dominant and stroma-poor composite ganglioneuroblastoma9.6ERBB2, KRAS
45breast papillary carcinoma9.5ERBB2, KRAS, PIK3CA
46dermatosis papulosa nigra9.5ERBB2, KRAS, PIK3CA
47adenosquamous carcinoma9.5ERBB2, KRAS, PIK3CA
48progesterone-receptor positive breast cancer9.5ERBB2, FGFR2, PIK3CA
49ovarian cancer, somatic9.3CDH1, ERBB2, KRAS, PIK3CA
50dental caries9.3CDH1, ERBB2, KRAS, PIK3CA

Graphical network of the top 20 diseases related to Gastric Cancer, Somatic:



Diseases related to gastric cancer, somatic

Symptoms & Phenotypes for Gastric Cancer, Somatic

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Clinical features from OMIM:

613659

Human phenotypes related to Gastric Cancer, Somatic:

 64
id Description HPO Frequency HPO Source Accession
1 stomach cancer64 HP:0012126

UMLS symptoms related to Gastric Cancer, Somatic:


abdominal pain, constipation, diarrhea, dyspepsia, heartburn, nausea and vomiting, gastrointestinal gas

GenomeRNAi Phenotypes related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00381-A-19.1CDH1, FGFR2, KRAS

MGI Mouse Phenotypes related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

41 (show all 15)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053828.3APC, CTNNBIP1, ERBB2, FGFR2, KRAS
2MP:00053678.3APC, CTNNBIP1, FGFR2, IRF1, KRAS
3MP:00053907.7APC, CTNNBIP1, ERBB2, FGFR2, IRF1, KRAS
4MP:00028737.6APC, CDH1, ERBB2, FGFR2, IRF1, KRAS
5MP:00053897.3APC, CDH1, ERBB2, FGFR2, KLF6, KRAS
6MP:00020067.1APC, CDH1, ERBB2, FGFR2, IRF1, KRAS
7MP:00053817.0APC, CDH1, CTNNBIP1, ERBB2, FGFR2, KRAS
8MP:00053797.0APC, CDH1, ERBB2, FGFR2, IRF1, KLF6
9MP:00107716.8APC, CDH1, ERBB2, FGFR2, IRF1, KLF6
10MP:00053806.8APC, CDH1, CTNNBIP1, ERBB2, FGFR2, KLF6
11MP:00053766.8APC, CDH1, ERBB2, FGFR2, IRF1, KRAS
12MP:00053856.5APC, CDH1, ERBB2, FGFR2, IRF1, KLF6
13MP:00053786.5APC, CDH1, CTNNBIP1, ERBB2, FGFR2, KLF6
14MP:00053846.1APC, CDH1, CTNNBIP1, ERBB2, FGFR2, IRF1
15MP:00107685.9APC, CDH1, CTNNBIP1, ERBB2, FGFR2, IRF1

Drugs & Therapeutics for Gastric Cancer, Somatic

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Drugs for Gastric Cancer, Somatic (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Rucaparibapproved, investigationalPhase 2, Phase 114283173-50-29931954
Synonyms:
AG-014699
 
AG014699
PF-01367338
rucaparib
2Poly(ADP-ribose) Polymerase InhibitorsPhase 2, Phase 1309

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study of Rucaparib in Patients With Pancreatic Cancer and a Known Deleterious BRCA MutationCompletedNCT02042378Phase 2
2A Study of Oral Rucaparib in Patients With a Solid Tumor (Phase I) or With gBRCA Mutation Ovarian Cancer (Phase II)Active, not recruitingNCT01482715Phase 1, Phase 2
3Phenotyping of Small Bowel AdenocarcinomaNot yet recruitingNCT02976090

Search NIH Clinical Center for Gastric Cancer, Somatic

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Gastric Cancer, Somatic cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Gastric Cancer, Somatic:
Tumor infiltrating lymphocytes (TILs) for solid tumors
Embryonic/Adult Cultured Cells Related to Gastric Cancer, Somatic:
Tumor infiltrating lymphocytes, PMIDs: 24329789, 19342963, 23904171, 21498393, 22996367, 19304471, 22555974, 15800326, 23650429, 21325070, 24218514, 8170938, 12242449

Genetic Tests for Gastric Cancer, Somatic

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Genetic tests related to Gastric Cancer, Somatic:

id Genetic test Affiliating Genes
1 Gastric Cancer, Somatic24 KRAS, FGFR2, PIK3CA

Anatomical Context for Gastric Cancer, Somatic

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MalaCards organs/tissues related to Gastric Cancer, Somatic:

36
Colon, Small intestine, Lymph node

Publications for Gastric Cancer, Somatic

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Variations for Gastric Cancer, Somatic

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UniProtKB/Swiss-Prot genetic disease variations for Gastric Cancer, Somatic:

70 (show all 17)
id Symbol AA change Variation ID SNP ID
1APCp.Gly817CysVAR_005035
2APCp.Ile880ThrVAR_005036
3APCp.Asn942AspVAR_005039
4APCp.Gly1120GluVAR_005042rs28933379
5APCp.Arg1171HisVAR_005043rs372481703
6APCp.Phe1197SerVAR_005045
7APCp.Ile1259ThrVAR_005046
8APCp.Gly1312GluVAR_005050
9APCp.Val1326AlaVAR_005052
10CASP10p.Met147ThrVAR_037428rs121909776
11IRF1p.Met8LeuVAR_065134rs121912469
12IRF1p.Trp11ArgVAR_065135rs121912470
13KRASp.Gly12ValVAR_006840rs121913529
14KRASp.Ala59ThrVAR_016030rs121913528
15KRASp.Lys5AsnVAR_064849rs104894361
16MUTYHp.Pro402SerVAR_026049rs121908382
17MUTYHp.Gln411ArgVAR_026050rs121908383

Clinvar genetic disease variations for Gastric Cancer, Somatic:

5 (show all 16)
id Gene Variation Type Significance SNP ID Assembly Location
1CDH1NM_004360.4(CDH1): c.2494G> A (p.Val832Met)SNVLikely pathogenic, Pathogenicrs35572355GRCh37Chr 16, 68867247: 68867247
2KRASNM_004985.4(KRAS): c.35G> A (p.Gly12Asp)SNVPathogenicrs121913529GRCh37Chr 12, 25398284: 25398284
3KRASNM_033360.3(KRAS): c.34G> A (p.Gly12Ser)SNVPathogenicrs121913530GRCh37Chr 12, 25398285: 25398285
4FGFR2NM_000141.4(FGFR2): c.799T> C (p.Ser267Pro)SNVPathogenicrs121918505GRCh37Chr 10, 123279633: 123279633
5PIK3CANM_006218.3(PIK3CA): c.3140A> G (p.His1047Arg)SNVPathogenicrs121913279GRCh37Chr 3, 178952085: 178952085
6PIK3CANM_006218.3(PIK3CA): c.1633G> A (p.Glu545Lys)SNVPathogenicrs104886003GRCh37Chr 3, 178936091: 178936091
7PIK3CANM_006218.3(PIK3CA): c.3203dupA (p.Asn1068Lysfs)duplicationPathogenicrs587776802GRCh37Chr 3, 178952148: 178952148
8ERBB2NM_001005862.2(ERBB2): c.2236G> A (p.Gly746Ser)SNVPathogenicrs28933369GRCh37Chr 17, 37880997: 37880997
9IRF1NM_002198.2(IRF1): c.22A> T (p.Met8Leu)SNVPathogenicrs121912469GRCh37Chr 5, 131825149: 131825149
10MUTYHNM_001128425.1(MUTYH): c.1213C> T (p.Pro405Ser)SNV, HaplotypePathogenicrs121908382GRCh37Chr 1, 45797202: 45797202
11MUTYHNM_001128425.1(MUTYH): c.1241A> G (p.Gln414Arg)SNVPathogenicrs121908383GRCh37Chr 1, 45797174: 45797174
12KLF6NM_001300.5(KLF6): c.465C> A (p.Ser155Arg)SNVPathogenicrs121909144GRCh37Chr 10, 3824044: 3824044
13CASP10NM_032977.3(CASP10): c.769C> T (p.Gln257Ter)SNVPathogenicrs121909775GRCh37Chr 2, 202070652: 202070652
14CASP10NM_032977.3(CASP10): c.440T> C (p.Met147Thr)SNVPathogenicrs121909776GRCh37Chr 2, 202052521: 202052521
15APCNM_000038.5(APC): c.3359G> A (p.Gly1120Glu)SNVPathogenicrs28933379GRCh37Chr 5, 112174650: 112174650
16APCNM_000038.5(APC): c.3199C> T (p.Gln1067Ter)SNVPathogenicrs137854571GRCh37Chr 5, 112174490: 112174490

Cosmic variations for Gastric Cancer, Somatic:

8 (show top 50)    (show all 778)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1COSM20525STK26stomach,NS,carcinoma,adenocarcinomac.444C>Gp.A148A7
2COSM20551TRRAPstomach,NS,carcinoma,adenocarcinomac.5117G>Ap.R1706H7
3COSM1579018CDC42stomach,NS,carcinoma,adenocarcinomac.178+7A>Gp.?7
4COSM44091TP53stomach,NS,carcinoma,adenocarcinomac.746G>Ap.R249K7
5COSM44151TP53stomach,NS,carcinoma,adenocarcinomac.535C>Ap.H179N7
6COSM5279PTENstomach,NS,carcinoma,adenocarcinomac.610C>Ap.P204T7
7COSM760PIK3CAstomach,NS,carcinoma,adenocarcinomac.1624G>Ap.E542K7
8COSM4062177CDH1stomach,NS,carcinoma,adenocarcinomac.569A>Gp.Y190C7
9COSM767PIK3CAstomach,NS,carcinoma,adenocarcinomac.1637A>Cp.Q546P7
10COSM10648TP53stomach,NS,carcinoma,adenocarcinomac.524G>Ap.R175H7
11COSM5576263CDH1stomach,NS,carcinoma,adenocarcinomac.466T>Ap.W156R7
12COSM1716270AXIN1stomach,NS,carcinoma,adenocarcinomac.1591C>Ap.H531N7
13COSM10704TP53stomach,NS,carcinoma,adenocarcinomac.844C>Tp.R282W7
14COSM10656TP53stomach,NS,carcinoma,adenocarcinomac.742C>Tp.R248W7
15COSM5575863KMT2Cstomach,NS,carcinoma,adenocarcinomac.13602G>Cp.Q4534H7
16COSM5576251LRP1Bstomach,NS,carcinoma,adenocarcinomac.8269+2T>Cp.?7
17COSM10705TP53stomach,NS,carcinoma,adenocarcinomac.586C>Tp.R196*7
18COSM5576102ZNF521stomach,NS,carcinoma,adenocarcinomac.443G>Ap.C148Y7
19COSM5670CTNNB1stomach,NS,carcinoma,adenocarcinomac.101G>Tp.G34V7
20COSM5576226RETstomach,NS,carcinoma,adenocarcinomac.898G>Ap.D300N7
21COSM5576053NSD2stomach,NS,carcinoma,adenocarcinomac.3235G>Ap.A1079T7
22COSM10663TP53stomach,NS,carcinoma,adenocarcinomac.916C>Tp.R306*7
23COSM133015ARID1Astomach,NS,carcinoma,adenocarcinomac.5359G>Tp.E1787*7
24COSM266035ARID2stomach,NS,carcinoma,adenocarcinomac.925A>Gp.N309D7
25COSM43826TP53stomach,NS,carcinoma,adenocarcinomac.706T>Ap.Y236N7
26COSM521KRASstomach,NS,carcinoma,adenocarcinomac.35G>Ap.G12D7
27COSM5576192DICER1stomach,NS,carcinoma,adenocarcinomac.322C>Gp.Q108E7
28COSM5575994NUP214stomach,NS,carcinoma,adenocarcinomac.6140G>Tp.G2047V7
29COSM763PIK3CAstomach,NS,carcinoma,adenocarcinomac.1633G>Ap.E545K7
30COSM483HRASstomach,NS,carcinoma,adenocarcinomac.35G>Tp.G12V7
31COSM5575902PTPN11stomach,NS,carcinoma,adenocarcinomac.222G>Cp.L74F7
32COSM14062ERBB2stomach,NS,carcinoma,adenocarcinomac.2329G>Tp.V777L7
33COSM5575798MYH9stomach,NS,carcinoma,adenocarcinomac.5677C>Tp.R1893C7
34COSM11089TP53stomach,NS,carcinoma,adenocarcinomac.584T>Cp.I195T7
35COSM10709TP53stomach,NS,carcinoma,adenocarcinomac.722C>Gp.S241C7
36COSM685ERBB2stomach,NS,carcinoma,adenocarcinomac.2326G>Ap.G776S7
37COSM20569EPHA2stomach,NS,carcinoma,adenocarcinomac.2329G>Ap.G777S7
38COSM20537MLKLstomach,NS,carcinoma,adenocarcinomac.872T>Cp.L291P7
39COSM20558TGFBR2stomach,NS,carcinoma,adenocarcinomac.181T>Cp.C61R7
40COSM20550TRRAPstomach,NS,carcinoma,adenocarcinomac.477A>Gp.K159K7
41COSM20528TNK2stomach,NS,carcinoma,adenocarcinomac.1227G>Ap.M409I7
42COSM21289TEX14stomach,NS,carcinoma,adenocarcinomac.961G>Ap.E321K7
43COSM21278MLKLstomach,NS,carcinoma,adenocarcinomac.1192T>Ap.F398I7
44COSM5575620ADGRL3stomach,NS,carcinoma,adenocarcinomac.1023C>Ap.Y341*7
45COSM45620TP53stomach,NS,carcinoma,adenocarcinomac.704A>Cp.N235T7
46COSM5575913ERCC4stomach,NS,carcinoma,adenocarcinomac.2026G>Tp.E676*7
47COSM5575897ROS1stomach,NS,carcinoma,adenocarcinomac.89T>Ap.L30*7
48COSM14065ERBB2stomach,NS,carcinoma,adenocarcinomac.2524G>Ap.V842I7
49COSM5576132SETD2stomach,NS,carcinoma,adenocarcinomac.2168C>Ap.P723Q7
50COSM10735TP53stomach,NS,carcinoma,adenocarcinomac.638G>Ap.R213Q7

Expression for genes affiliated with Gastric Cancer, Somatic

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Search GEO for disease gene expression data for Gastric Cancer, Somatic.

Pathways for genes affiliated with Gastric Cancer, Somatic

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Pathways related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

(show all 40)
idSuper pathwaysScoreTop Affiliating Genes
1
Show member pathways
9.7FGFR2, PIK3CA
29.5KRAS, PIK3CA
39.3CDH1, PIK3CA
49.3CDH1, PIK3CA
59.3CDH1, PIK3CA
6
Show member pathways
9.2CASP10, KRAS, PIK3CA
79.1IRF1, KRAS, PIK3CA
8
Show member pathways
9.1FGFR2, KRAS, PIK3CA
99.0CDH1, KRAS
109.0APC, CASP10, CDH1
11
Show member pathways
9.0ERBB2, KRAS, PIK3CA
12
Show member pathways
9.0APC, CDH1, PIK3CA
139.0ERBB2, KRAS, PIK3CA
14
Show member pathways
9.0ERBB2, KRAS, PIK3CA
15
Show member pathways
9.0ERBB2, KRAS, PIK3CA
16
Show member pathways
8.9ERBB2, FGFR2, KRAS
178.9CDH1, FGFR2, PIK3CA
18
Show member pathways
8.8CASP10, IRF1, KRAS, PIK3CA
198.8APC, CDH1, CTNNBIP1
208.8CDH1, ERBB2, PIK3CA
21
Show member pathways
8.7APC, FGFR2, KRAS, PIK3CA
228.7APC, FGFR2, KRAS, PIK3CA
238.7APC, CDH1, KRAS
248.7APC, CDH1, KRAS
258.6APC, ERBB2, KRAS, PIK3CA
26
Show member pathways
8.6ERBB2, IRF1, KRAS, PIK3CA
27
Show member pathways
8.5ERBB2, FGFR2, KRAS, PIK3CA
288.5ERBB2, FGFR2, KRAS, PIK3CA
298.5CDH1, ERBB2, KRAS
308.3APC, CASP10, ERBB2, KRAS, PIK3CA
31
Show member pathways
8.2CASP10, ERBB2, FGFR2, KRAS, PIK3CA
32
Show member pathways
8.2CDH1, FGFR2, KRAS, PIK3CA
33
Show member pathways
8.2APC, ERBB2, FGFR2, KRAS, PIK3CA
34
Show member pathways
7.9CDH1, FGFR2, IRF1, KRAS, PIK3CA
35
Show member pathways
7.8APC, CDH1, ERBB2, KRAS, PIK3CA
36
Show member pathways
7.8APC, CDH1, ERBB2, KRAS, PIK3CA
37
Show member pathways
7.8CASP10, CDH1, ERBB2, FGFR2, KRAS
38
Show member pathways
7.8APC, CDH1, ERBB2, FGFR2, KRAS
39
Show member pathways
7.7CDH1, ERBB2, FGFR2, KRAS, PIK3CA
407.4APC, CDH1, ERBB2, FGFR2, KRAS, PIK3CA

GO Terms for genes affiliated with Gastric Cancer, Somatic

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Cellular components related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1beta-catenin destruction complexGO:003087710.2APC, CTNNBIP1
2catenin complexGO:00163429.9APC, CDH1
3lamellipodiumGO:00300279.0APC, CDH1, PIK3CA

Biological processes related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1regulation of multicellular organism growthGO:004001410.2FGFR2, PIK3CA
2regulation of microtubule-based processGO:003288610.2APC, ERBB2
3regulation of ERK1 and ERK2 cascadeGO:007037210.1ERBB2, FGFR2
4phosphatidylinositol phosphorylationGO:00468549.8ERBB2, FGFR2, PIK3CA
5phosphatidylinositol-mediated signalingGO:00480159.7ERBB2, FGFR2, PIK3CA
6ERBB2 signaling pathwayGO:00381289.6ERBB2, KRAS, PIK3CA
7regulation of phosphatidylinositol 3-kinase signalingGO:00140669.2ERBB2, FGFR2, PIK3CA

Molecular functions related to Gastric Cancer, Somatic according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1gamma-catenin bindingGO:004529510.2APC, CDH1
2phosphatidylinositol-4,5-bisphosphate 3-kinase activityGO:004693410.0ERBB2, FGFR2, PIK3CA
3beta-catenin bindingGO:00080139.6APC, CDH1, CTNNBIP1
4protein bindingGO:00055155.5APC, CASP10, CDH1, CTNNBIP1, ERBB2, FGFR2

Sources for Gastric Cancer, Somatic

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet