MCID: GST060
MIFTS: 43

Gastric Cancer, Somatic malady

Genetic diseases (common), Gastrointestinal diseases, Cancer diseases categories

Summaries for Gastric Cancer, Somatic

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OMIM:46 In a review article on the genetic predisposition to gastric cancer, Bevan and Houlston (1999) concluded that several... (613659) more...

MalaCards based summary: Gastric Cancer, Somatic is related to hereditary diffuse gastric cancer and intestinal neoplasm, and has symptoms including somatic mutationand stomach cancer. An important gene associated with Gastric Cancer, Somatic is FGFR2 (fibroblast growth factor receptor 2), and among its related pathways are Alzheimers Disease Pathway and SHC1 events in ERBB2 signaling. The compounds pki-166 and af/ap have been mentioned in the context of this disorder. Affiliated tissues include colon, and related mouse phenotypes are pigmentation and limbs/digits/tail.

Description from OMIM:46 137215

Aliases & Classifications for Gastric Cancer, Somatic

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Gastric Cancer, Somatic, Aliases & Descriptions:

Name: Gastric Cancer, Somatic 46


Classifications:



Related Diseases for Gastric Cancer, Somatic

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Diseases related to Gastric Cancer, Somatic via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 57)
idRelated DiseaseScoreTop Affiliating Genes
1hereditary diffuse gastric cancer10.4CDH1
2intestinal neoplasm10.4APC
3malignant mixed mullerian tumor10.3ERBB2, KRAS
4gastric cancer10.3
5stomach cancer10.3CDH1, ERBB2
6bronchiolo-alveolar adenocarcinoma10.2KRAS, CDH1
7large cell carcinoma10.2KRAS, ERBB2
8inflammatory breast carcinoma10.2CDH1, ERBB2
9breast cancer, invasive ductal10.2ERBB2, CDH1
10ductal carcinoma in situ10.2ERBB2, CDH1
11gallbladder cancer10.2APC, KRAS
12tubular adenocarcinoma10.2CDH1, ERBB2
13breast ductal carcinoma10.2CDH1, ERBB2
14breast cancer, somatic10.1KRAS, PIK3CA
15salivary gland adenoid cystic carcinoma10.1CDH1, ERBB2
16endometrial carcinoma10.1CDH1, KRAS, ERBB2
17transitional cell carcinoma10.1FGFR2, CDH1, ERBB2
18bladder carcinoma10.1FGFR2, CDH1, ERBB2
19hepatitis b10.1IRF1, KLF6, KRAS
20nonsmall cell lung cancer, somatic10.1IRF1, PIK3CA
21bladder carcinoma in situ10.1CDH1, ERBB2
22factor vii deficiency10.0KRAS, ERBB2
23lynch syndrome10.0APC, MUTYH, KRAS
24rectal neoplasm10.0KRAS, MUTYH, APC
25colorectal cancer, somatic10.0APC, PIK3CA
26nasopharynx carcinoma9.9PIK3CA, KLF6, CDH1
27thyroid adenoma9.9APC, PIK3CA
28prostate cancer9.9ERBB2, CDH1, FGFR2
29thyroid cancer, anaplastic9.9PIK3CA, CDH1
30acute leukemia9.9PIK3CA, IRF1, KRAS
31thyroid hurthle cell carcinoma9.9PIK3CA, APC, FGFR2
32squamous cell carcinoma of the head and neck9.9PIK3CA, ERBB2, CDH1
33cervical cancer9.9KRAS, IRF1, PIK3CA
34lung cancer9.8PIK3CA, ERBB2, KRAS
35astrocytoma9.8PIK3CA, IRF1, KLF6, FGFR2
36brain cancer9.8PIK3CA, APC, KLF6
37cholangiocarcinoma9.8PIK3CA, ERBB2, KRAS, CDH1
38adenoma9.8APC, MUTYH, KRAS, CDH1
39medulloblastoma9.7PIK3CA, APC, ERBB2, FGFR2
40kidney cancer9.7PIK3CA, IRF1, CDH1, FGFR2
41burkitt's lymphoma9.7KRAS, CASP10, IRF1, PIK3CA
42glioblastoma9.7PIK3CA, IRF1, ERBB2, KLF6, FGFR2
43colonic benign neoplasm9.6PIK3CA, APC, KRAS, CDH1
44pancreatic cancer9.6PIK3CA, ERBB2, KRAS, CDH1, FGFR2
45lung adenocarcinoma9.6PIK3CA, ERBB2, KLF6, KRAS, CDH1
46leukemia9.6FGFR2, KRAS, CASP10, IRF1, PIK3CA
47familial adenomatous polyposis9.6KRAS, IRF1, MUTYH, APC, CDH1
48ovarian cancer9.6CDH1, KRAS, ERBB2, IRF1, PIK3CA
49gastric adenocarcinoma9.5PIK3CA, APC, ERBB2, KRAS, CDH1
50breast cancer9.5PIK3CA, APC, ERBB2, KRAS, CDH1

Graphical network of the top 20 diseases related to Gastric Cancer, Somatic:



Diseases related to gastric cancer, somatic

Symptoms for Gastric Cancer, Somatic

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Clinical features from OMIM:

613659,137215

HPO human phenotypes related to Gastric Cancer, Somatic:

id Description Frequency HPO Source Accession
1 somatic mutation HP:0001428
2 stomach cancer HP:0012126

Drugs & Therapeutics for Gastric Cancer, Somatic

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Drug clinical trials:

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Genetic Tests for Gastric Cancer, Somatic

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Anatomical Context for Gastric Cancer, Somatic

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MalaCards organs/tissues related to Gastric Cancer, Somatic:

32
Colon

Animal Models for Gastric Cancer, Somatic or affiliated genes

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Publications for Gastric Cancer, Somatic

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Variations for Gastric Cancer, Somatic

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UniProtKB/Swiss-Prot genetic disease variations for Gastric Cancer, Somatic:

63 (show all 23)
id Symbol AA change Variation ID SNP ID
1APCp.Gly817CysVAR_005035
2APCp.Ile880ThrVAR_005036
3APCp.Asn942AspVAR_005039
4APCp.Gly1120GluVAR_005042rs28933379
5APCp.Arg1171HisVAR_005043
6APCp.Phe1197SerVAR_005045
7APCp.Ile1259ThrVAR_005046
8APCp.Gly1312GluVAR_005050
9APCp.Val1326AlaVAR_005052
10CASP10p.Met147ThrVAR_037428rs121909776
11CDH1p.Asp244GlyVAR_008712
12CDH1p.Val487AlaVAR_008713
13CDH1p.Val832MetVAR_023358rs35572355
14IRF1p.Met8LeuVAR_065134
15IRF1p.Trp11ArgVAR_065135
16KRASp.Gly12ValVAR_006840
17KRASp.Gly12AspVAR_016026
18KRASp.Gly12SerVAR_016028
19KRASp.Gly13AspVAR_016029
20KRASp.Ala59ThrVAR_016030
21KRASp.Lys5AsnVAR_064849
22MUTYHp.Pro402SerVAR_026049
23MUTYHp.Gln411ArgVAR_026050

Clinvar genetic disease variations for Gastric Cancer, Somatic:

7 (show all 34)
id Gene Name Type Significance SNP ID Assembly Location
1CDH1NM_004360.3(CDH1): c.1849G> A (p.Ala617Thr)single nucleotide variantPathogenicrs33935154GRCh37Chr 16, 68856041: 68856041
2CDH1NM_004360.3(CDH1): c.781G> T (p.Glu261Ter)single nucleotide variantPathogenicrs121964873GRCh37Chr 16, 68844193: 68844193
3CDH1CDH1, 1-BP INS, 2382CinsertionPathogenic
4CDH1NM_004360.3(CDH1): c.2095C> T (p.Gln699Ter)single nucleotide variantPathogenicrs121964874GRCh37Chr 16, 68857460: 68857460
5CDH1CDH1, IVS1AS, A-G, -2single nucleotide variantPathogenic
6CDH1NM_004360.3(CDH1): c.59G> A (p.Trp20Ter)single nucleotide variantPathogenicrs121964875GRCh37Chr 16, 68772210: 68772210
7CDH1NM_004360.3(CDH1): c.70G> T (p.Glu24Ter)single nucleotide variantPathogenicrs121964876GRCh37Chr 16, 68772221: 68772221
8CDH1NM_004360.3(CDH1): c.1792C> T (p.Arg598Ter)single nucleotide variantPathogenicrs121964877GRCh37Chr 16, 68855984: 68855984
9CDH1CDH1, 1-BP INS, 1711GinsertionPathogenic
10CDH1CDH1, 1-BP INS, 1588CinsertionPathogenic
11CDH1NM_004360.3(CDH1): c.1901C> T (p.Ala634Val)single nucleotide variantPathogenicrs121964878GRCh37Chr 16, 68856093: 68856093
12CDH1NM_004360.3(CDH1): c.1018A> G (p.Thr340Ala)single nucleotide variantPathogenicrs116093741GRCh37Chr 16, 68846047: 68846047
13CDH1NM_004360.3(CDH1): c.2494G> A (p.Val832Met)single nucleotide variantPathogenicrs35572355GRCh37Chr 16, 68867247: 68867247
14CDH1nsv513771deletionPathogenic
15CDH1CDH1, 828-BP DEL/3-BP INS, EX16indelPathogenic
16KRASNM_033360.3(KRAS): c.35G> A (p.Gly12Asp)single nucleotide variantPathogenic, drug responsers121913529GRCh37Chr 12, 25398284: 25398284
17KRASNM_033360.3(KRAS): c.34G> A (p.Gly12Ser)single nucleotide variantPathogenic, drug responsers121913530GRCh37Chr 12, 25398285: 25398285
18CDH1NM_004360.3(CDH1): c.1565+1G> Asingle nucleotide variantPathogenicGRCh38Chr 16, 68815760: 68815760
19FGFR2NM_000141.4(FGFR2): c.799T> C (p.Ser267Pro)single nucleotide variantPathogenicrs121918505GRCh37Chr 10, 123279633: 123279633
20CDH1NM_004360.3(CDH1): c.1003C> T (p.Arg335Ter)single nucleotide variantPathogenicGRCh38Chr 16, 68811854: 68811854
21CDH1NM_004360.3(CDH1): c.2287G> T (p.Glu763Ter)single nucleotide variantPathogenicGRCh38Chr 16, 68828296: 68828296
22PIK3CANM_006218.2(PIK3CA): c.3140A> G (p.His1047Arg)single nucleotide variantPathogenicrs121913279GRCh37Chr 3, 178952085: 178952085
23PIK3CANM_006218.2(PIK3CA): c.1633G> A (p.Glu545Lys)single nucleotide variantPathogenicrs104886003GRCh37Chr 3, 178936091: 178936091
24PIK3CANM_006218.2(PIK3CA): c.3203dupA (p.Asn1068Lysfs)duplicationPathogenicGRCh37Chr 3, 178952148: 178952148
25ERBB2NM_001005862.2(ERBB2): c.2236G> A (p.Gly746Ser)single nucleotide variantPathogenicrs28933369GRCh37Chr 17, 37880997: 37880997
26IRF1NM_002198.2(IRF1): c.22A> T (p.Met8Leu)single nucleotide variantPathogenicrs121912469GRCh37Chr 5, 131825149: 131825149
27CDH1NM_004360.3(CDH1): c.1008G> T (p.Glu336Asp)single nucleotide variantPathogenicrs267606712GRCh37Chr 16, 68845762: 68845762
28MUTYHNM_001128425.1(MUTYH): c.1213C> T (p.Pro405Ser)single nucleotide variantPathogenicrs121908382GRCh37Chr 1, 45797202: 45797202
29MUTYHNM_001128425.1(MUTYH): c.1241A> G (p.Gln414Arg)single nucleotide variantPathogenicrs121908383GRCh37Chr 1, 45797174: 45797174
30KLF6NM_001300.5(KLF6): c.465C> A (p.Ser155Arg)single nucleotide variantPathogenicrs121909144GRCh37Chr 10, 3824044: 3824044
31CASP10NM_032977.3(CASP10): c.769C> T (p.Gln257Ter)single nucleotide variantPathogenicrs121909775GRCh37Chr 2, 202070652: 202070652
32CASP10NM_032977.3(CASP10): c.440T> C (p.Met147Thr)single nucleotide variantPathogenicrs121909776GRCh37Chr 2, 202052521: 202052521
33APCNM_000038.5(APC): c.3359G> A (p.Gly1120Glu)single nucleotide variantPathogenicrs28933379GRCh37Chr 5, 112174650: 112174650
34APCNM_000038.5(APC): c.3199C> T (p.Gln1067Ter)single nucleotide variantPathogenicrs137854571GRCh37Chr 5, 112174490: 112174490

Expression for genes affiliated with Gastric Cancer, Somatic

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Expression patterns in normal tissues for genes affiliated with Gastric Cancer, Somatic

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Pathways for genes affiliated with Gastric Cancer, Somatic

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Pathways related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8FGFR2, ERBB2
2
Show member pathways
9.8KRAS, ERBB2
39.6CDH1, KRAS
49.5ERBB2, KRAS, FGFR2
5
Show member pathways
Angiogenesis37
9.4PIK3CA, FGFR2
69.3PIK3CA, KRAS
79.3KRAS, PIK3CA
89.3ERBB2, PIK3CA
9
Show member pathways
9.3FGFR2, CDH1, ERBB2
109.2CASP10, ERBB2, CDH1
119.1CDH1, PIK3CA
129.1CDH1, PIK3CA
139.1CDH1, PIK3CA
14
Show member pathways
9.0FGFR2, KRAS, PIK3CA
15
Show member pathways
9.0PIK3CA, KRAS, FGFR2
16
Show member pathways
9.0FGFR2, KRAS, PIK3CA
179.0PIK3CA, ERBB2, KRAS
18
Show member pathways
ErbB receptor signaling network37
ErbB signaling pathway37
9.0PIK3CA, ERBB2, KRAS
19
Show member pathways
9.0KRAS, ERBB2, PIK3CA
20
Show member pathways
Development EGFR signaling via PIP359
Development PDGF signaling via MAPK cascades59
Apoptosis and survival Anti apoptotic action of membrane bound ESR159
Signaling of Hepatocyte Growth Factor Receptor37
Development EGFR signaling via small GTPases59
Development Neurotrophin family signaling59
Apoptosis and survival NGF signaling pathway59
Apoptosis and survival Role of CDK5 in neuronal death and survival59
9.0KRAS, ERBB2, PIK3CA
21
Show member pathways
Transcription Receptor mediated HIF regulation59
Development CNTF receptor signaling59
Class IB PI3K non-lipid kinase events37
ErbB2/ErbB3 signaling events37
Development Growth hormone signaling via PI3K AKT and MAPK cascades59
Translation Regulation activity of EIF259
Regulation of lipid metabolism Insulin signaling generic cascades59
Transcription PPAR Pathway59
Cell adhesion PLAU signaling59
Translation Regulation activity of EIF4F59
9.0KRAS, ERBB2, PIK3CA
22
Show member pathways
Toll-like receptor signaling pathway37
Regulation of toll-like receptor signaling pathway37
8.9PIK3CA, CASP10, KRAS
238.9APC, CASP10, CDH1
24
Show member pathways
8.9KRAS, IRF1, PIK3CA
25
Show member pathways
IL-9 Signaling Pathway37
Development Thrombopoietin regulated cell processes59
IL-7 Signaling Pathway37
Immune response IL 9 signaling pathway59
8.9KRAS, IRF1, PIK3CA
268.9KRAS, IRF1, PIK3CA
27
Show member pathways
8.9CASP10, ERBB2, CDH1, FGFR2
288.8FGFR2, CDH1, PIK3CA
298.8CDH1, ERBB2, PIK3CA
30
Show member pathways
Development ERBB family signaling59
Development GDNF family signaling59
8.8PIK3CA, ERBB2, CDH1
318.7PIK3CA, APC, KRAS
32
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
33
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
34
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
35
Show member pathways
8.7APC, ERBB2, CDH1, FGFR2
36
Show member pathways
8.6FGFR2, KRAS, CASP10, PIK3CA
37
Show member pathways
8.5FGFR2, CDH1, KRAS, PIK3CA
388.5CDH1, APC, PIK3CA
39
Show member pathways
RAC1 signaling pathway37
8.5PIK3CA, APC, CDH1
40
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling59
Leptin signaling pathway37
8.5PIK3CA, IRF1, ERBB2, KRAS
41
Show member pathways
8.4PIK3CA, APC, KRAS, FGFR2
428.3KRAS, ERBB2, APC, PIK3CA
43
Show member pathways
8.2PIK3CA, CASP10, ERBB2, KRAS, FGFR2
44
Show member pathways
8.2APC, CASP10, ERBB2, CDH1, FGFR2
45
Show member pathways
Signaling Pathways in Glioblastoma37
8.1FGFR2, CDH1, KRAS, ERBB2, PIK3CA
46
Show member pathways
8.1PIK3CA, ERBB2, KRAS, CDH1, FGFR2
47
Show member pathways
8.0PIK3CA, APC, ERBB2, KRAS, FGFR2
487.9PIK3CA, APC, CASP10, ERBB2, KRAS
49
Show member pathways
Signal transduction PTEN pathway59
7.8PIK3CA, APC, ERBB2, KRAS, CDH1
507.5FGFR2, CDH1, KRAS, ERBB2, APC, PIK3CA

Compounds for genes affiliated with Gastric Cancer, Somatic

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Compounds related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1pki-166449.8CDH1, ERBB2
2af/ap449.7MUTYH, APC
3irinotecan44 50 1211.5ERBB2, KRAS, CDH1
4p002449.5ERBB2, KRAS, CDH1
5suberoylanilide hydroxamic acid449.5CDH1, ERBB2, IRF1
6o6-methylguanine449.4CDH1, KRAS, APC
7exisulind449.4APC, CDH1
8adriamycin449.3CDH1, ERBB2, IRF1
9trastuzumab44 50 1211.3FGFR2, ERBB2, PIK3CA
10cyclophosphamide44 50 1211.3FGFR2, ERBB2, MUTYH
11celecoxib44 60 29 50 25 1214.3APC, ERBB2, CDH1
12imatinib44 50 1211.1KRAS, ERBB2, PIK3CA
13guanine44 25 1211.0APC, MUTYH, ERBB2, FGFR2
14docetaxel44 50 60 1212.0PIK3CA, ERBB2, CDH1
15folate449.0CDH1, ERBB2, APC
16egcg448.9CDH1, ERBB2, PIK3CA
17erlotinib44 50 1210.9PIK3CA, ERBB2, KRAS, CDH1
18gefitinib44 50 1210.9PIK3CA, ERBB2, KRAS, CDH1
19curcumin448.9APC, ERBB2, CDH1
20agar448.8FGFR2, CDH1, ERBB2, PIK3CA
21phosphotyrosine448.8FGFR2, CDH1, ERBB2, PIK3CA
22adenine44 25 1210.8APC, MUTYH, IRF1, CDH1
23vitamin d448.8FGFR2, CDH1, KRAS, ERBB2, APC
24paraffin448.7APC, ERBB2, KRAS, CDH1, FGFR2
25doxorubicin44 50 1210.7FGFR2, CDH1, ERBB2, PIK3CA
26ly294002448.7CDH1, KRAS, ERBB2, PIK3CA
275-aza-2deoxycytidine448.7FGFR2, CDH1, APC
28genistein44 29 60 3 25 1213.7FGFR2, CDH1, ERBB2, PIK3CA
29etoposide44 50 60 1211.7PIK3CA, IRF1, ERBB2, CDH1
30crcs448.6CDH1, KRAS, APC, PIK3CA
315fluorouracil448.6PIK3CA, ERBB2, KRAS, CDH1, FGFR2
32h2o2448.5PIK3CA, MUTYH, ERBB2, KRAS, FGFR2
33vegf448.5PIK3CA, ERBB2, KRAS, CDH1, FGFR2
34tamoxifen44 50 29 1211.4FGFR2, CDH1, ERBB2, IRF1, PIK3CA
35arginine448.3PIK3CA, IRF1, ERBB2, CDH1, FGFR2
36adp44 29 2510.3PIK3CA, APC, ERBB2, KLF6, FGFR2
37wortmannin448.2PIK3CA, APC, ERBB2, KRAS, CDH1
38heparin44 29 25 1211.2PIK3CA, APC, ERBB2, CDH1, FGFR2
39progesterone44 29 60 25 1212.2PIK3CA, APC, ERBB2, CDH1, FGFR2
40testosterone44 60 25 1211.2PIK3CA, APC, ERBB2, CDH1, FGFR2
41paclitaxel44 50 1210.2PIK3CA, CASP10, ERBB2, KRAS, CDH1, FGFR2
42lipid448.1PIK3CA, APC, IRF1, KRAS, FGFR2
43rapamycin448.0PIK3CA, APC, ERBB2, KRAS, CDH1, FGFR2
44adenylate447.8PIK3CA, APC, IRF1, KLF6, CDH1, FGFR2
45retinoic acid44 258.8PIK3CA, APC, IRF1, KRAS, CDH1, FGFR2
46cisplatin44 50 60 1210.7PIK3CA, MUTYH, CASP10, ERBB2, KRAS, CDH1
47phosphatidylinositol447.5PIK3CA, APC, IRF1, ERBB2, KRAS, CDH1
48tyrosine447.5PIK3CA, APC, IRF1, ERBB2, KRAS, CDH1
49estrogen447.2PIK3CA, APC, IRF1, ERBB2, KLF6, KRAS
50serine446.8FGFR2, PIK3CA, APC, IRF1, CASP10, ERBB2

GO Terms for genes affiliated with Gastric Cancer, Somatic

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Cellular components related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lateral plasma membraneGO:0163289.3CDH1, APC
2cell-cell adherens junctionGO:0059139.0CDH1, APC
3cytoplasmGO:0057377.3APC, IRF1, CASP10, ERBB2, KLF6, CDH1
4plasma membraneGO:0058867.1FGFR2, PIK3CA, APC, CASP10, ERBB2, KRAS

Biological processes related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1regulation of ERK1 and ERK2 cascadeGO:07037210.1FGFR2, ERBB2
2neuromuscular junction developmentGO:00752810.0ERBB2, FGFR2
3positive regulation of MAP kinase activityGO:0434069.8ERBB2, KRAS
4regulation of osteoblast differentiationGO:0456679.8FGFR2, APC
5positive regulation of epithelial cell proliferationGO:0506799.8FGFR2, ERBB2
6regulation of microtubule-based processGO:0328869.7ERBB2, APC
7positive regulation of cell adhesionGO:0457859.6ERBB2, APC
8cytokine-mediated signaling pathwayGO:0192219.6KRAS, KLF6, IRF1
9regulation of multicellular organism growthGO:0400149.6FGFR2, PIK3CA
10positive regulation of cell divisionGO:0517819.6APC, FGFR2
11negative regulation of epithelial cell proliferationGO:0506809.6CDH1, FGFR2
12tight junction assemblyGO:0708309.4CDH1, APC
13insulin receptor signaling pathwayGO:0082869.3PIK3CA, KRAS, FGFR2
14phosphatidylinositol-mediated signalingGO:0480159.3PIK3CA, ERBB2, FGFR2
15cellular component disassembly involved in execution phase of apoptosisGO:0069219.0APC, CDH1
16fibroblast growth factor receptor signaling pathwayGO:0085439.0FGFR2, KRAS, ERBB2, PIK3CA
17Fc-epsilon receptor signaling pathwayGO:0380959.0PIK3CA, ERBB2, KRAS, FGFR2
18epidermal growth factor receptor signaling pathwayGO:0071739.0FGFR2, KRAS, ERBB2, PIK3CA
19neurotrophin TRK receptor signaling pathwayGO:0480119.0PIK3CA, ERBB2, KRAS, FGFR2
20innate immune responseGO:0450878.6FGFR2, KRAS, ERBB2, CASP10, PIK3CA
21apoptotic processGO:0069158.5APC, IRF1, CASP10, CDH1, FGFR2

Molecular functions related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1gamma-catenin bindingGO:0452959.3CDH1, APC
2protein bindingGO:0055155.8FGFR2, PIK3CA, APC, MUTYH, IRF1, CASP10

Products for genes affiliated with Gastric Cancer, Somatic

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Sources for Gastric Cancer, Somatic

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
29IUPHAR
30KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
57SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet