MCID: GST060
MIFTS: 50

Gastric Cancer, Somatic malady

Genetic diseases, Gastrointestinal diseases, Cancer diseases, Rare diseases categories

Summaries for Gastric Cancer, Somatic

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48OMIM, 34MalaCards
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MalaCards: Gastric Cancer, Somatic, also known as malignant neoplasm of stomach, is related to stomach cancer and hereditary diffuse gastric cancer. An important gene associated with Gastric Cancer, Somatic is FGFR2 (fibroblast growth factor receptor 2), and among its related pathways are Alzheimers Disease Pathway and SHC1 events in ERBB2 signaling. The compounds pki-166 and af/ap have been mentioned in the context of this disorder. Affiliated tissues include colon, and related mouse phenotypes are pigmentation and limbs/digits/tail.

Description from OMIM:48 613659,137215

Aliases & Classifications for Gastric Cancer, Somatic

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50Orphanet, 48OMIM, 63UMLS, 60SNOMED-CT via Orphanet, 27ICD10 via Orphanet
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Classifications:



Characteristics (Orphanet epidemiological data):

50
gastric cancer:
Inheritance: Multigenic/multifactorial,Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

gastric cancer, somatic 48
malignant neoplasm of stomach 63
gastric cancer 50
stomach cancer 50


External Ids:

SNOMED-CT via Orphanet60 363349007
OMIM48 613659
ICD10 via Orphanet27 C16

Related Diseases for Gastric Cancer, Somatic

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18GeneCards, 19GeneDecks
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Diseases related to Gastric Cancer, Somatic via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 273)
idRelated DiseaseScoreTop Affiliating Genes
1stomach cancer32.1CDH1, ERBB2
2hereditary diffuse gastric cancer30.3CDH1
3melanoma30.3PIK3CA, IRF1, CASP10, KRAS, CDH1, FGFR2
4tubular adenocarcinoma30.3CDH1, ERBB2
5leukemia30.2FGFR2, KRAS, CASP10, IRF1, PIK3CA
6lung cancer30.2PIK3CA, ERBB2, KRAS
7pancreatic cancer30.2PIK3CA, ERBB2, KRAS, CDH1, FGFR2
8lynch syndrome30.1APC, MUTYH, KRAS
9prostate cancer30.0ERBB2, CDH1, FGFR2
10colon cancer30.0PIK3CA, APC, KRAS, CDH1
11gastric adenocarcinoma30.0PIK3CA, APC, ERBB2, KRAS, CDH1
12breast cancer30.0PIK3CA, APC, ERBB2, KRAS, CDH1
13familial adenomatous polyposis29.9KRAS, IRF1, MUTYH, APC, CDH1
14adenocarcinoma29.9PIK3CA, APC, IRF1, ERBB2, KLF6, KRAS
15inflammatory breast carcinoma29.9CDH1, ERBB2
16cervical cancer29.9KRAS, IRF1, PIK3CA
17adenoma29.8APC, MUTYH, KRAS, CDH1
18retinoblastoma29.8PIK3CA, APC, IRF1, ERBB2, KLF6, KRAS
19cholangiocarcinoma29.8PIK3CA, ERBB2, KRAS, CDH1
20lung adenocarcinoma29.7PIK3CA, ERBB2, KLF6, KRAS, CDH1
21colorectal cancer29.6PIK3CA, FGFR2, CDH1, KRAS, KLF6, ERBB2
22hepatocellular carcinoma29.5PIK3CA, APC, MUTYH, IRF1, KLF6, KRAS
23diffuse gastric cancer10.9
24hypoxia10.6
25h. pylori infection10.6
26pancreatitis10.4
27esophagitis10.4
28gastritis10.4
29disseminated intravascular coagulation10.4
30atrophic gastritis10.4
31microinvasive gastric cancer10.3
32cronkhite-canada syndrome10.3
33situs inversus10.3
34li-fraumeni syndrome10.2
35ataxia telangiectasia10.2
36pyloric stenosis10.2
37ataxia10.2
38malt lymphoma10.2
39stomach cancer, familial10.2
40gastric lymphoma10.2
41xeroderma pigmentosum10.2
42thyroiditis10.2
43plummer vinson syndrome10.2
44pernicious anemia10.2
45peritonitis10.2
46stomach cancer, childhood10.2
47gastric outlet obstruction10.2
48obstructive jaundice10.1
49dumping syndrome10.1
50peutz-jeghers syndrome10.1

Graphical network of the top 20 diseases related to Gastric Cancer, Somatic:



Diseases related to gastric cancer, somatic

Symptoms for Gastric Cancer, Somatic

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48OMIM
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Clinical features from OMIM:

613659,137215

Drugs & Therapeutics for Gastric Cancer, Somatic

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6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

Search CenterWatch for Gastric Cancer, Somatic

Drug clinical trials:

Search ClinicalTrials for Gastric Cancer, Somatic

Search NIH Clinical Center for Gastric Cancer, Somatic

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Genetic Tests for Gastric Cancer, Somatic

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Anatomical Context for Gastric Cancer, Somatic

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34MalaCards
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MalaCards organs/tissues related to Gastric Cancer, Somatic:

34
Colon

Animal Models for Gastric Cancer, Somatic or affiliated genes

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38MGI
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Publications for Gastric Cancer, Somatic

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Variations for Gastric Cancer, Somatic

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Sources:
65UniProtKB/Swiss-Prot, 1 National Center for Biotechnology Information (Clinvar), 8dbSNP
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UniProtKB/Swiss-Prot genetic disease variations for Gastric Cancer, Somatic:

65 (show all 23)
id Symbol AA change Variation ID SNP ID
1APCp.Gly817CysVAR_005035
2APCp.Ile880ThrVAR_005036
3APCp.Asn942AspVAR_005039
4APCp.Gly1120GluVAR_005042rs28933379
5APCp.Arg1171HisVAR_005043
6APCp.Phe1197SerVAR_005045
7APCp.Ile1259ThrVAR_005046
8APCp.Gly1312GluVAR_005050
9APCp.Val1326AlaVAR_005052
10CASP10p.Met147ThrVAR_037428rs121909776
11CDH1p.Asp244GlyVAR_008712
12CDH1p.Val487AlaVAR_008713
13CDH1p.Val832MetVAR_023358rs35572355
14IRF1p.Met8LeuVAR_065134
15IRF1p.Trp11ArgVAR_065135
16KRASp.Gly12ValVAR_006840
17KRASp.Gly12AspVAR_016026
18KRASp.Gly12SerVAR_016028
19KRASp.Gly13AspVAR_016029
20KRASp.Ala59ThrVAR_016030
21KRASp.Lys5AsnVAR_064849
22MUTYHp.Pro402SerVAR_026049
23MUTYHp.Gln411ArgVAR_026050

Clinvar genetic disease variations for Gastric Cancer, Somatic:

1 (show all 34)
id Gene Name Type Significance SNP ID Assembly Location
1CDH1NM_004360.3(CDH1): c.1849G> A (p.Ala617Thr)single nucleotide variantBenign, Pathogenicrs33935154GRCh37Chr 16, 68856041: 68856041
2CDH1NM_004360.3(CDH1): c.781G> T (p.Glu261Ter)single nucleotide variantPathogenicrs121964873GRCh37Chr 16, 68844193: 68844193
3CDH1CDH1, 1-BP INS, 2382CinsertionPathogenic
4CDH1NM_004360.3(CDH1): c.2095C> T (p.Gln699Ter)single nucleotide variantPathogenicrs121964874GRCh37Chr 16, 68857460: 68857460
5CDH1CDH1, IVS1AS, A-G, -2single nucleotide variantPathogenic
6CDH1NM_004360.3(CDH1): c.59G> A (p.Trp20Ter)single nucleotide variantPathogenicrs121964875GRCh37Chr 16, 68772210: 68772210
7CDH1NM_004360.3(CDH1): c.70G> T (p.Glu24Ter)single nucleotide variantPathogenicrs121964876GRCh37Chr 16, 68772221: 68772221
8CDH1NM_004360.3(CDH1): c.1792C> T (p.Arg598Ter)single nucleotide variantPathogenicrs121964877GRCh37Chr 16, 68855984: 68855984
9CDH1CDH1, 1-BP INS, 1711GinsertionPathogenic
10CDH1CDH1, 1-BP INS, 1588CinsertionPathogenic
11CDH1NM_004360.3(CDH1): c.1901C> T (p.Ala634Val)single nucleotide variantPathogenicrs121964878GRCh37Chr 16, 68856093: 68856093
12CDH1NM_004360.3(CDH1): c.1018A> G (p.Thr340Ala)single nucleotide variantPathogenic, Uncertain significancers116093741GRCh37Chr 16, 68846047: 68846047
13CDH1NM_004360.3(CDH1): c.2494G> A (p.Val832Met)single nucleotide variantPathogenic, Uncertain significancers35572355GRCh37Chr 16, 68867247: 68867247
14CDH1nsv513771deletionPathogenic
15CDH1CDH1, 828-BP DEL/3-BP INS, EX16indelPathogenic
16KRASNM_033360.3(KRAS): c.35G> A (p.Gly12Asp)single nucleotide variantPathogenic, drug responsers121913529GRCh37Chr 12, 25398284: 25398284
17KRASNM_033360.3(KRAS): c.34G> A (p.Gly12Ser)single nucleotide variantPathogenic, drug responsers121913530GRCh37Chr 12, 25398285: 25398285
18CDH1NM_004360.3(CDH1): c.1565+1G> Asingle nucleotide variantPathogenicGRCh38Chr 16, 68815760: 68815760
19FGFR2NM_000141.4(FGFR2): c.799T> C (p.Ser267Pro)single nucleotide variantPathogenicrs121918505GRCh37Chr 10, 123279633: 123279633
20CDH1NM_004360.3(CDH1): c.1003C> T (p.Arg335Ter)single nucleotide variantPathogenicGRCh38Chr 16, 68811854: 68811854
21CDH1NM_004360.3(CDH1): c.2287G> T (p.Glu763Ter)single nucleotide variantPathogenicGRCh38Chr 16, 68828296: 68828296
22PIK3CANM_006218.2(PIK3CA): c.3140A> G (p.His1047Arg)single nucleotide variantPathogenicrs121913279GRCh37Chr 3, 178952085: 178952085
23PIK3CANM_006218.2(PIK3CA): c.1633G> A (p.Glu545Lys)single nucleotide variantPathogenicrs104886003GRCh37Chr 3, 178936091: 178936091
24PIK3CANM_006218.2(PIK3CA): c.3203dupA (p.Asn1068Lysfs)duplicationPathogenicGRCh37Chr 3, 178952148: 178952148
25ERBB2NM_001005862.2(ERBB2): c.2236G> A (p.Gly746Ser)single nucleotide variantPathogenicrs28933369GRCh37Chr 17, 37880997: 37880997
26IRF1NM_002198.2(IRF1): c.22A> T (p.Met8Leu)single nucleotide variantPathogenicrs121912469GRCh37Chr 5, 131825149: 131825149
27CDH1NM_004360.3(CDH1): c.1008G> T (p.Glu336Asp)single nucleotide variantPathogenicrs267606712GRCh37Chr 16, 68845762: 68845762
28MUTYHNM_001128425.1(MUTYH): c.1213C> T (p.Pro405Ser)single nucleotide variantPathogenicrs121908382GRCh37Chr 1, 45797202: 45797202
29MUTYHNM_001128425.1(MUTYH): c.1241A> G (p.Gln414Arg)single nucleotide variantPathogenicrs121908383GRCh37Chr 1, 45797174: 45797174
30KLF6NM_001300.5(KLF6): c.465C> A (p.Ser155Arg)single nucleotide variantPathogenicrs121909144GRCh37Chr 10, 3824044: 3824044
31CASP10NM_032977.3(CASP10): c.769C> T (p.Gln257Ter)single nucleotide variantPathogenicrs121909775GRCh37Chr 2, 202070652: 202070652
32CASP10NM_032977.3(CASP10): c.440T> C (p.Met147Thr)single nucleotide variantPathogenicrs121909776GRCh37Chr 2, 202052521: 202052521
33APCNM_000038.5(APC): c.3359G> A (p.Gly1120Glu)single nucleotide variantPathogenicrs28933379GRCh37Chr 5, 112174650: 112174650
34APCNM_000038.5(APC): c.3199C> T (p.Gln1067Ter)single nucleotide variantPathogenicrs137854571GRCh37Chr 5, 112174490: 112174490

Expression for genes affiliated with Gastric Cancer, Somatic

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gastric Cancer, Somatic

Search GEO for disease gene expression data for Gastric Cancer, Somatic.

Pathways for genes affiliated with Gastric Cancer, Somatic

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Sources:
51PathCards, 54QIAGEN, 56Reactome, 31KEGG, 55R&D Systems, 5Cell Signaling Technology, 39NCBI BioSystems Database, 61Thomson Reuters, 58SinoBiological, 52PharmGKB, 62Tocris Bioscience
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Pathways related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 57)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8FGFR2, ERBB2
2
Show member pathways
9.8KRAS, ERBB2
39.6CDH1, KRAS
49.5ERBB2, KRAS, FGFR2
5
Show member pathways
Angiogenesis39
9.4PIK3CA, FGFR2
69.3PIK3CA, KRAS
79.3KRAS, PIK3CA
89.3ERBB2, PIK3CA
9
Show member pathways
9.3FGFR2, CDH1, ERBB2
109.2CASP10, ERBB2, CDH1
119.1CDH1, PIK3CA
129.1CDH1, PIK3CA
139.1CDH1, PIK3CA
14
Show member pathways
9.0FGFR2, KRAS, PIK3CA
15
Show member pathways
9.0PIK3CA, KRAS, FGFR2
16
Show member pathways
9.0FGFR2, KRAS, PIK3CA
179.0PIK3CA, ERBB2, KRAS
18
Show member pathways
ErbB receptor signaling network39
ErbB signaling pathway39
9.0PIK3CA, ERBB2, KRAS
19
Show member pathways
9.0KRAS, ERBB2, PIK3CA
20
Show member pathways
Development EGFR signaling via PIP361
Development PDGF signaling via MAPK cascades61
Apoptosis and survival Anti apoptotic action of membrane bound ESR161
Signaling of Hepatocyte Growth Factor Receptor39
Development EGFR signaling via small GTPases61
Development Neurotrophin family signaling61
Apoptosis and survival NGF signaling pathway61
Apoptosis and survival Role of CDK5 in neuronal death and survival61
9.0KRAS, ERBB2, PIK3CA
21
Show member pathways
Transcription Receptor mediated HIF regulation61
Development CNTF receptor signaling61
Class IB PI3K non-lipid kinase events39
ErbB2/ErbB3 signaling events39
Development Growth hormone signaling via PI3K AKT and MAPK cascades61
Translation Regulation activity of EIF261
Regulation of lipid metabolism Insulin signaling generic cascades61
Transcription PPAR Pathway61
Cell adhesion PLAU signaling61
Translation Regulation activity of EIF4F61
9.0KRAS, ERBB2, PIK3CA
22
Show member pathways
Toll-like receptor signaling pathway39
Regulation of toll-like receptor signaling pathway39
8.9PIK3CA, CASP10, KRAS
238.9APC, CASP10, CDH1
24
Show member pathways
8.9KRAS, IRF1, PIK3CA
25
Show member pathways
IL-9 Signaling Pathway39
Development Thrombopoietin regulated cell processes61
IL-7 Signaling Pathway39
Immune response IL 9 signaling pathway61
8.9KRAS, IRF1, PIK3CA
268.9KRAS, IRF1, PIK3CA
27
Show member pathways
8.9CASP10, ERBB2, CDH1, FGFR2
288.8FGFR2, CDH1, PIK3CA
298.8CDH1, ERBB2, PIK3CA
30
Show member pathways
Development ERBB family signaling61
Development GDNF family signaling61
8.8PIK3CA, ERBB2, CDH1
318.7PIK3CA, APC, KRAS
32
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
33
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
34
Show member pathways
8.7PIK3CA, ERBB2, KRAS, FGFR2
35
Show member pathways
8.7APC, ERBB2, CDH1, FGFR2
36
Show member pathways
8.6FGFR2, KRAS, CASP10, PIK3CA
37
Show member pathways
8.5FGFR2, CDH1, KRAS, PIK3CA
388.5CDH1, APC, PIK3CA
39
Show member pathways
RAC1 signaling pathway39
8.5PIK3CA, APC, CDH1
40
Show member pathways
Prolactin Signaling Pathway39
Development Prolactin receptor signaling61
Leptin signaling pathway39
8.5PIK3CA, IRF1, ERBB2, KRAS
41
Show member pathways
8.4PIK3CA, APC, KRAS, FGFR2
428.3KRAS, ERBB2, APC, PIK3CA
43
Show member pathways
8.2PIK3CA, CASP10, ERBB2, KRAS, FGFR2
44
Show member pathways
8.2APC, CASP10, ERBB2, CDH1, FGFR2
45
Show member pathways
Signaling Pathways in Glioblastoma39
8.1FGFR2, CDH1, KRAS, ERBB2, PIK3CA
46
Show member pathways
8.1PIK3CA, ERBB2, KRAS, CDH1, FGFR2
47
Show member pathways
8.0PIK3CA, APC, ERBB2, KRAS, FGFR2
487.9PIK3CA, APC, CASP10, ERBB2, KRAS
49
Show member pathways
Signal transduction PTEN pathway61
7.8PIK3CA, APC, ERBB2, KRAS, CDH1
507.5FGFR2, CDH1, KRAS, ERBB2, APC, PIK3CA

Compounds for genes affiliated with Gastric Cancer, Somatic

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Sources:
46Novoseek, 52PharmGKB, 12DrugBank, 62Tocris Bioscience, 30IUPHAR, 25HMDB, 3BitterDB
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Compounds related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show top 50)    (show all 78)
idCompoundScoreTop Affiliating Genes
1pki-166469.8CDH1, ERBB2
2af/ap469.7MUTYH, APC
3irinotecan46 52 1211.5ERBB2, KRAS, CDH1
4p002469.5ERBB2, KRAS, CDH1
5suberoylanilide hydroxamic acid469.5CDH1, ERBB2, IRF1
6o6-methylguanine469.4CDH1, KRAS, APC
7exisulind469.4APC, CDH1
8adriamycin469.3CDH1, ERBB2, IRF1
9trastuzumab46 52 1211.3FGFR2, ERBB2, PIK3CA
10cyclophosphamide46 52 1211.3FGFR2, ERBB2, MUTYH
11celecoxib46 62 30 52 25 1214.3APC, ERBB2, CDH1
12imatinib46 52 1211.1KRAS, ERBB2, PIK3CA
13guanine46 25 1211.0APC, MUTYH, ERBB2, FGFR2
14docetaxel46 52 62 1212.0PIK3CA, ERBB2, CDH1
15folate469.0CDH1, ERBB2, APC
16egcg468.9CDH1, ERBB2, PIK3CA
17erlotinib46 52 1210.9PIK3CA, ERBB2, KRAS, CDH1
18gefitinib46 52 1210.9PIK3CA, ERBB2, KRAS, CDH1
19curcumin468.9APC, ERBB2, CDH1
20agar468.8FGFR2, CDH1, ERBB2, PIK3CA
21phosphotyrosine468.8FGFR2, CDH1, ERBB2, PIK3CA
22adenine46 25 1210.8APC, MUTYH, IRF1, CDH1
23vitamin d468.8FGFR2, CDH1, KRAS, ERBB2, APC
24paraffin468.7APC, ERBB2, KRAS, CDH1, FGFR2
25doxorubicin46 52 1210.7FGFR2, CDH1, ERBB2, PIK3CA
26ly294002468.7CDH1, KRAS, ERBB2, PIK3CA
275-aza-2deoxycytidine468.7FGFR2, CDH1, APC
28genistein46 30 62 3 25 1213.7FGFR2, CDH1, ERBB2, PIK3CA
29etoposide46 52 62 1211.7PIK3CA, IRF1, ERBB2, CDH1
30crcs468.6CDH1, KRAS, APC, PIK3CA
315fluorouracil468.6PIK3CA, ERBB2, KRAS, CDH1, FGFR2
32h2o2468.5PIK3CA, MUTYH, ERBB2, KRAS, FGFR2
33vegf468.5PIK3CA, ERBB2, KRAS, CDH1, FGFR2
34tamoxifen46 52 30 1211.4FGFR2, CDH1, ERBB2, IRF1, PIK3CA
35arginine468.3PIK3CA, IRF1, ERBB2, CDH1, FGFR2
36adp46 30 2510.3PIK3CA, APC, ERBB2, KLF6, FGFR2
37wortmannin468.2PIK3CA, APC, ERBB2, KRAS, CDH1
38heparin46 30 25 1211.2PIK3CA, APC, ERBB2, CDH1, FGFR2
39progesterone46 30 62 25 1212.2PIK3CA, APC, ERBB2, CDH1, FGFR2
40testosterone46 62 25 1211.2PIK3CA, APC, ERBB2, CDH1, FGFR2
41paclitaxel46 52 1210.2PIK3CA, CASP10, ERBB2, KRAS, CDH1, FGFR2
42lipid468.1PIK3CA, APC, IRF1, KRAS, FGFR2
43rapamycin468.0PIK3CA, APC, ERBB2, KRAS, CDH1, FGFR2
44adenylate467.8PIK3CA, APC, IRF1, KLF6, CDH1, FGFR2
45retinoic acid46 258.8PIK3CA, APC, IRF1, KRAS, CDH1, FGFR2
46cisplatin46 52 62 1210.7PIK3CA, MUTYH, CASP10, ERBB2, KRAS, CDH1
47phosphatidylinositol467.5PIK3CA, APC, IRF1, ERBB2, KRAS, CDH1
48tyrosine467.5PIK3CA, APC, IRF1, ERBB2, KRAS, CDH1
49estrogen467.2PIK3CA, APC, IRF1, ERBB2, KLF6, KRAS
50serine466.8FGFR2, PIK3CA, APC, IRF1, CASP10, ERBB2

GO Terms for genes affiliated with Gastric Cancer, Somatic

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17Gene Ontology
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Cellular components related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lateral plasma membraneGO:0163289.3CDH1, APC
2cell-cell adherens junctionGO:0059139.0CDH1, APC
3cytoplasmGO:0057377.3APC, IRF1, CASP10, ERBB2, KLF6, CDH1
4plasma membraneGO:0058867.1FGFR2, PIK3CA, APC, CASP10, ERBB2, KRAS

Biological processes related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1regulation of ERK1 and ERK2 cascadeGO:07037210.1FGFR2, ERBB2
2neuromuscular junction developmentGO:00752810.0ERBB2, FGFR2
3positive regulation of MAP kinase activityGO:0434069.8ERBB2, KRAS
4regulation of osteoblast differentiationGO:0456679.8FGFR2, APC
5positive regulation of epithelial cell proliferationGO:0506799.8FGFR2, ERBB2
6regulation of microtubule-based processGO:0328869.7ERBB2, APC
7positive regulation of cell adhesionGO:0457859.6ERBB2, APC
8cytokine-mediated signaling pathwayGO:0192219.6KRAS, KLF6, IRF1
9regulation of multicellular organism growthGO:0400149.6FGFR2, PIK3CA
10positive regulation of cell divisionGO:0517819.6APC, FGFR2
11negative regulation of epithelial cell proliferationGO:0506809.6CDH1, FGFR2
12tight junction assemblyGO:0708309.4CDH1, APC
13insulin receptor signaling pathwayGO:0082869.3PIK3CA, KRAS, FGFR2
14phosphatidylinositol-mediated signalingGO:0480159.3PIK3CA, ERBB2, FGFR2
15cellular component disassembly involved in execution phase of apoptosisGO:0069219.0APC, CDH1
16fibroblast growth factor receptor signaling pathwayGO:0085439.0FGFR2, KRAS, ERBB2, PIK3CA
17Fc-epsilon receptor signaling pathwayGO:0380959.0PIK3CA, ERBB2, KRAS, FGFR2
18epidermal growth factor receptor signaling pathwayGO:0071739.0FGFR2, KRAS, ERBB2, PIK3CA
19neurotrophin TRK receptor signaling pathwayGO:0480119.0PIK3CA, ERBB2, KRAS, FGFR2
20innate immune responseGO:0450878.6FGFR2, KRAS, ERBB2, CASP10, PIK3CA
21apoptotic processGO:0069158.5APC, IRF1, CASP10, CDH1, FGFR2

Molecular functions related to Gastric Cancer, Somatic according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1gamma-catenin bindingGO:0452959.3CDH1, APC
2protein bindingGO:0055155.8FGFR2, PIK3CA, APC, MUTYH, IRF1, CASP10

Products for genes affiliated with Gastric Cancer, Somatic

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  • Antibodies
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Sources for Gastric Cancer, Somatic

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet