MCID: GST007
MIFTS: 38

Gastric Dilatation malady

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Dilatation

Aliases & Descriptions for Gastric Dilatation:

Name: Gastric Dilatation 12 42 14 69
Stomach Dilatation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3229
MeSH 42 D013271
UMLS 69 C0038353

Summaries for Gastric Dilatation

MalaCards based summary : Gastric Dilatation, also known as stomach dilatation, is related to obesity and anorexia nervosa. An important gene associated with Gastric Dilatation is MANBA (Mannosidase Beta), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Gamma carboxylation, hypusine formation and arylsulfatase activation. The drugs Citalopram and Reboxetine have been mentioned in the context of this disorder. Affiliated tissues include lung, testes and liver, and related phenotypes are hearing/vestibular/ear and renal/urinary system

Related Diseases for Gastric Dilatation

Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to Gastric Dilatation

Symptoms & Phenotypes for Gastric Dilatation

MGI Mouse Phenotypes related to Gastric Dilatation:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 hearing/vestibular/ear MP:0005377 9.13 ARSB IDUA ITGB4
2 renal/urinary system MP:0005367 8.92 ARSB IDUA ITGB4 MANBA

Drugs & Therapeutics for Gastric Dilatation

Drugs for Gastric Dilatation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 172)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Citalopram Approved Phase 4 59729-33-8 2771
2
Reboxetine Approved, Investigational Phase 4 98769-81-4, 71620-89-8 123628 65856
3
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
4
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
5
Methylene blue Investigational Phase 4 61-73-4
6 Adrenergic Agents Phase 4,Phase 3
7 Antidepressive Agents Phase 4
8 Antidepressive Agents, Second-Generation Phase 4
9 Antiparkinson Agents Phase 4
10 Autonomic Agents Phase 4,Phase 2
11 Cholinergic Agents Phase 4
12 Cholinergic Antagonists Phase 4
13 Muscarinic Antagonists Phase 4
14 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
15 Neurotransmitter Uptake Inhibitors Phase 4
16 Parasympatholytics Phase 4
17 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
18 Psychotropic Drugs Phase 4,Phase 2
19
Serotonin Phase 4,Phase 3 50-67-9 5202
20 Serotonin Agents Phase 4,Phase 3
21 Serotonin Uptake Inhibitors Phase 4
22 Anesthetics Phase 4,Phase 3,Phase 2
23 Anesthetics, Local Phase 4,Phase 2,Phase 3
24 Anti-Infective Agents Phase 4,Phase 2,Phase 3
25 Anti-Infective Agents, Local Phase 4
26 Chlorhexidine gluconate Phase 4
27 Disinfectants Phase 4
28 Anticholesteremic Agents Phase 4
29 Antimetabolites Phase 4,Phase 2,Phase 3
30 Atorvastatin Calcium Phase 4 134523-03-8
31 Calcium, Dietary Phase 4
32 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
33 Hypolipidemic Agents Phase 4,Phase 2,Phase 3
34 Lipid Regulating Agents Phase 4,Phase 2,Phase 3
35 Rosuvastatin Calcium Phase 4 147098-20-2
36 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
37 Antibiotics, Antitubercular Phase 4
38 Antimalarials Phase 4
39 Antiparasitic Agents Phase 4
40 Antiprotozoal Agents Phase 4
41 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
42
Proton pump inhibitors Phase 4,Phase 2,Phase 3
43 Antacids Phase 4
44 Anti-Ulcer Agents Phase 4
45 Cola Nutraceutical Phase 4,Phase 2
46
Erythromycin Approved, Vet_approved Phase 2, Phase 3 114-07-8 12560
47
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
48
Lidocaine Approved, Vet_approved Phase 2, Phase 3 137-58-6 3676
49
Nadolol Approved Phase 3 42200-33-9 39147
50
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037

Interventional clinical trials:

(show top 50) (show all 113)
id Name Status NCT ID Phase
1 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755 Phase 4
2 Banded Versus Conventional Laparoscopic Roux-en-Y (GABY) Unknown status NCT01015469 Phase 4
3 Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder Unknown status NCT00209807 Phase 4
4 Personalized Peroral Endoscopic Myotomy for Achalasia Unknown status NCT01570621 Phase 4
5 Comparison of Laryngeal Mask Airway Supreme and Endotracheal Tube In Patients Undergoing Gynecological Laparoscopy Surgery Completed NCT02127632 Phase 4
6 Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury Completed NCT00987974 Phase 4
7 Do Nasogastric Tubes After Cardiac Surgery Reduce Nausea and Vomiting Completed NCT00193999 Phase 4
8 Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants Completed NCT02140710 Phase 4
9 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
10 Serum Levels of Doxycycline at the Time of Abortion With Two Dosing Regimens Completed NCT00177333 Phase 4
11 Gastric vs Jejunal Feeding in Diabetic Gastroparesis Withdrawn NCT00944593 Phase 4
12 Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis Withdrawn NCT01497743 Phase 4
13 Dexilant Treatment in Gastrointestinal Reflux Disease (GERD Related Non Cardiac Chest Pain Withdrawn NCT01637571 Phase 4
14 A Study to Evaluate the Effect and Safety of Idoform Plus on Bowel Side Effects in Healthy Subjects Treated With Amoxicillin/ Clavulanate Withdrawn NCT01491659 Phase 4
15 Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs Unknown status NCT01081561 Phase 2, Phase 3
16 Electroacupuncture Versus Fast-track Perioperative Program for Laparoscopic Colorectal Surgery Unknown status NCT02059603 Phase 3
17 Laryngeal Masks for Bariatric Surgery Unknown status NCT01724970 Phase 3
18 Endoscopic Band Ligation Versus Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical Trial Completed NCT01601639 Phase 3
19 The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia. Completed NCT00171457 Phase 3
20 Cyrotherapy vs. APC in GAVE Completed NCT00587405 Phase 2, Phase 3
21 Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility Completed NCT01379183 Phase 2, Phase 3
22 Impact of Gastric Bypass Surgery on Risk of CVD in Type 2 Diabetes Mellitus Completed NCT00444392 Phase 3
23 Acu-TENS for Pain Relief During Colonoscopy Completed NCT01751815 Phase 3
24 Noninvasive Continuous Positive Airway Pressure (NCPAP) in Children Completed NCT01242150 Phase 3
25 Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery Completed NCT00464425 Phase 3
26 Effectiveness and Safety of Lidocaine for Scleroderma Completed NCT00740285 Phase 2, Phase 3
27 Randomized Trial of Nasal Continuous Positive Airway Pressure or Synchronized Nasal Ventilation in Premature Infants. Completed NCT00188968 Phase 3
28 Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass Terminated NCT00394212 Phase 3
29 StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight Terminated NCT00939055 Phase 2, Phase 3
30 Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding Terminated NCT00409084 Phase 3
31 Tethered Capsule Endoscope in Screening Participants for Barrett Esophagus Unknown status NCT00903136 Phase 1, Phase 2
32 An Exploratory Study Examining The Effects Of Taking GW679769 Once-Daily For 4 Days In Patients With Functional Dyspepsia Completed NCT00358410 Phase 2
33 Evaluation of the Safety and Effectiveness of Stomaphyx for Transoral Incisionless Reduction of the Enlarged Gastric Pouch and Stoma Completed NCT01025076 Phase 2
34 Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation Completed NCT00964496 Phase 2
35 SAFEstart Feeding Intolerance Study Phase II Completed NCT00331201 Phase 2
36 Effect of a Cannabinoid Agonist on Colonic Sensory Functions in Patients With Irritable Bowel Syndrome Completed NCT01786109 Phase 2
37 Pectin Start Early Enteral Nutritional Support in Critically Ill Patients Completed NCT02379624 Phase 1, Phase 2
38 Uncut Roux-en-Y Gastrojejunostomy for Early Gastric Cancer Patients Recruiting NCT02644148 Phase 2
39 Gastric Sleeve Pilot Study in Morbidly Obese Undergoing Liver Transplantation Completed NCT02068872 Phase 1
40 Post-marketing Surveillance Study of A.M.I. Protector Adjustable Gastric Band Unknown status NCT01752829
41 Banded Versus Non-banded Roux-en-Y Gastric Bypass Unknown status NCT01078181
42 A Randomized Comparison of Laparoscopic Myotomy and Pneumatic Dilatation for Achalasia Unknown status NCT00188344
43 Carbon Dioxide Versus Air Insufflation in Oesophago-Gastro-Duodenoscopy (OGD) Unknown status NCT00627211
44 Pyloric Sphincter Pressure and Geometry Assessment Using EndoFlip Unknown status NCT02446119
45 Is Nasogastric Tube Necessary After Pancreaticoduodenectomy? Unknown status NCT01991392
46 Is Nasogastric Tube Necessary After Pancreaticoduodenectomy? Unknown status NCT01966406
47 Effect of Acupuncture to Endothelial Dysfunction Induced by Ischemia-reperfusion Injury Unknown status NCT02255006
48 Gastric Volumetry by Gastric Tomodensitometry With Gas Completed NCT01963637
49 Esophageal Dysmotility and Dilatation After Laparoscopic Gastric Banding Completed NCT01234428
50 Endolumenal Gastric Pouch and Gastrojejunal Anastomosis Reduction Completed NCT01003743

Search NIH Clinical Center for Gastric Dilatation

Cochrane evidence based reviews: gastric dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

MalaCards organs/tissues related to Gastric Dilatation:

39
Lung, Testes, Liver, Kidney

Publications for Gastric Dilatation

Articles related to Gastric Dilatation:

(show top 50) (show all 322)
id Title Authors Year
1
Unexpected Death Due to Acute Gastric Dilatation and Gastric Necrosis in an 11-Year-Old Boy. ( 27164319 )
2016
2
Dobutamine stress echocardiography resulting in acute gastric dilatation and pneumoporta. ( 27388544 )
2016
3
Unanswered questions on gastric dilatation/volvulus and gastropexy. ( 27980146 )
2016
4
Acute gastric dilatation in a bulimic patient. ( 26975234 )
2016
5
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. ( 27784838 )
2016
6
Use of a venting PEG tube in the management of recurrent acute gastric dilatation associated with Prader-Willi syndrome. ( 26763981 )
2016
7
Massive gastric dilatation: the radiological picture of eating disorder. ( 27041386 )
2016
8
Binge Eating Leading to Acute Gastric Dilatation, Ischemic Necrosis and Rupture -A Case Report. ( 27134932 )
2016
9
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
10
Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation. ( 27347832 )
2016
11
Portal vein gas secondary to acute non-obstructive gastric dilatation. ( 27916447 )
2016
12
Acute gastric dilatation in the context of bulimia nervosa. ( 26334471 )
2015
13
Hemostatic variables, plasma lactate concentration, and inflammatory biomarkers in dogs with gastric dilatation-volvulus. ( 26568318 )
2015
14
C-reactive protein and high mobility group box 1 in dogs with gastric dilatation and volvulus. ( 26088834 )
2015
15
Acute massive gastric dilatation with abdominal compartment syndrome in a patient with bulimia nervosa. ( 26077071 )
2015
16
Suspicion of superior mesenteric artery syndrome in a patient with severe gastric dilatation after catheter ablation. ( 25786450 )
2015
17
Severe Acute Postoperative Gastric Dilatation. ( 26158257 )
2015
18
What Is Your Diagnosis? Gastric dilatation-volvulus. ( 26594805 )
2015
19
Young Adult With Abdominal Pain. Gastric dilatation caused by anorexia nervosa. ( 26497441 )
2015
20
Delayed Pneumoperitoneum and Acute Pulmonary Edema Secondary to Acute Gastric Dilatation. ( 26668807 )
2015
21
Acute gastric dilatation in the context of bulimia nervosa. ( 26177084 )
2015
22
Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating. ( 25663789 )
2015
23
Acute gastric dilatation causing fatal outcome in a young female with eating disorder: a case report. ( 25844140 )
2015
24
Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. ( 25639251 )
2015
25
Life-threatening acute gastric dilatation with aorta compression in a 3-year-old child. ( 26387581 )
2015
26
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. ( 26459100 )
2015
27
Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid. ( 26457032 )
2015
28
Treatment of gastric dilatation in rabbits. ( 25103746 )
2014
29
Prolonged idiopathic gastric dilatation following revascularization for chronic mesenteric ischemia. ( 24975870 )
2014
30
Occurrence and recurrence of gastric dilatation with or without volvulus after incisional gastropexy. ( 25320388 )
2014
31
Gastric dilatation and volvulus in a brachycephalic dog with hiatal hernia. ( 24871205 )
2014
32
Cardiovascular and systemic effects of gastric dilatation and volvulus in dogs. ( 25496923 )
2014
33
Massive gastric dilatation in bulimic patient. ( 25223115 )
2014
34
Recurrent gastric dilatation and intestinal dysmotility possibly resulting from autonomic neuropathy in a Great Dane. ( 24659724 )
2014
35
Gastropexy for prevention of gastric dilatation-volvulus in dogs: history and techniques. ( 25496925 )
2014
36
Medical treatment of 145 cases of gastric dilatation in rabbits. ( 25013085 )
2014
37
Acute gastric dilatation due to a superior mesenteric artery syndrome: an autopsy case. ( 24555911 )
2014
38
A case report of percutaneous endoscopic gastrostomy left-side gastropexy to resolve a recurrent gastric dilatation in a dog previously treated with right-side gastropexy for gastric dilatation volvulus. ( 25813852 )
2014
39
Abdominal aortic occlusion and vascular compromise secondary to acute gastric dilatation in a patient with bulimia. ( 25350169 )
2014
40
Inherited and predisposing factors in the development of gastric dilatation volvulus in dogs. ( 25496921 )
2014
41
Gastric Dilatation and Volvulus in a Red Panda (Ailurus fulgens). ( 24467661 )
2014
42
Postoperative management of dogs with gastric dilatation and volvulus. ( 25496926 )
2014
43
Acute gastric dilatation causing acute limb ischemia in an anorexia nervosa patient. ( 24560015 )
2014
44
Gastric dilatation and volvulus in dogs. Foreword. ( 25496920 )
2014
45
Treatment of gastric dilatation in rabbits. ( 25103747 )
2014
46
The relationship between gastrointestinal motility and gastric dilatation-volvulus in dogs. ( 25496922 )
2014
47
13C-sodium acetate breath test for evaluation of gastric emptying times in dogs with gastric dilatation-volvulus. ( 23608963 )
2013
48
Concurrent gall bladder, liver lobe torsion, and bile peritonitis in a German shepherd dog 2 months after gastric dilatation/volvulus gastropexy and splenectomy. ( 24155480 )
2013
49
Total gastrectomy performed in emergency conditions for gastric necrosis due to acute gastric dilatation. ( 23958106 )
2013
50
Massive gastric dilation complicating diabetic gastroparesis. ( 23616329 )
2013

Variations for Gastric Dilatation

Expression for Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

GO Terms for Gastric Dilatation

Cellular components related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 lysosome GO:0005764 9.13 ARSB IDUA MANBA
2 lysosomal lumen GO:0043202 8.8 ARSB IDUA MANBA

Biological processes related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 autophagy GO:0006914 9.26 ARSB ITGB4
2 glycosphingolipid metabolic process GO:0006687 9.16 ARSB ARSH
3 chondroitin sulfate catabolic process GO:0030207 8.96 ARSB IDUA
4 metabolic process GO:0008152 8.92 ARSB ARSH IDUA MANBA

Molecular functions related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hydrolase activity GO:0016787 9.56 ARSB ARSH IDUA MANBA
2 hydrolase activity, acting on glycosyl bonds GO:0016798 9.16 IDUA MANBA
3 sulfuric ester hydrolase activity GO:0008484 8.96 ARSB ARSH
4 arylsulfatase activity GO:0004065 8.62 ARSB ARSH

Sources for Gastric Dilatation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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