MCID: GST007
MIFTS: 33

Gastric Dilatation malady

Gastrointestinal category

Summaries for Gastric Dilatation

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33MalaCards
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MalaCards: Gastric Dilatation, also known as stomach dilatation, is related to anorexia nervosa and superior mesenteric artery syndrome. An important gene associated with Gastric Dilatation is OPN1MW (opsin 1 (cone pigments), medium-wave-sensitive), and among its related pathways are Sphingolipid metabolism and PTM: gamma carboxylation, hypusine formation and arylsulfatase activation. The compounds sulfate and estrone sulfate have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, kidney and liver.

Aliases & Classifications for Gastric Dilatation

Sources:
8Disease Ontology, 10DISEASES, 61UMLS, 35MeSH
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal


Aliases & Descriptions:

gastric dilatation 8 10 61
stomach dilatation 8


External Ids:

Disease Ontology8 DOID:3229
MeSH35 D013271

Related Diseases for Gastric Dilatation

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to gastric dilatation

Clinical Features for Gastric Dilatation

Drugs & Therapeutics for Gastric Dilatation

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Gastric Dilatation

Drug clinical trials:

Search ClinicalTrials for Gastric Dilatation

Search NIH Clinical Center for Gastric Dilatation

Search CenterWatch for Gastric Dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

Sources:
33MalaCards
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MalaCards organs/tissues related to Gastric Dilatation:

33
Spinal cord, Kidney, Liver, Lung, Pancreatic islet

Animal Models for Gastric Dilatation or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Gastric Dilatation

Sources:
51PubMed
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Articles related to Gastric Dilatation:

(show top 50)    (show all 286)
idTitleAuthorsYear
1
Evaluation of plasma lactate concentration and base excess at the time of hospital admission as predictors of gastric necrosis and outcome and correlation between those variables in dogs with gastric dilatation-volvulus: 78 cases (2004-2009). (23234282)
2013
2
Massive gastric dilatation in a patient with type 2 diabetes. (23569171)
2013
3
An Internet-based survey of risk factors for surgical gastric dilatation-volvulus in dogs. (22657929)
2012
4
Comparison of Hb-200 and 6% hetastarch 450/0.7 during initial fluid resuscitation of 20 dogs with gastric dilatation-volvulus. (23016811)
2012
5
Silent acute gastric dilatation due to Salmonella infection in a diabetic elderly. (21893501)
2011
6
Mortality and morbidity due to gastric dilatation-volvulus syndrome in pedigree dogs in the UK. (20626784)
2010
7
Association between outcome and changes in plasma lactate concentration during presurgical treatment in dogs with gastric dilatation-volvulus: 64 cases (2002-2008). (20392189)
2010
8
Acute gastric dilatation. (19386863)
2009
9
Post-esophagectomy gastric outlet obstruction: role of pyloromyotomy and management with endoscopic pyloric dilatation. (17166733)
2007
10
Massive binge eating, gastric dilatation and unsuccessful purging in a young woman with bulimia nervosa. (17950174)
2007
11
Long-term follow-up of patients with gastric outlet obstruction related to peptic ulcer disease treated with endoscopic balloon dilatation and drug therapy. (17640640)
2007
12
The effect of ingredients in dry dog foods on the risk of gastric dilatation-volvulus in dogs. (16397192)
2006
13
Acute massive gastric dilatation: severe ischemia and gastric necrosis without perforation. (16200240)
2005
14
Images in clinical medicine. Gastric dilatation secondary to diabetic autonomic neuropathy. (16371635)
2005
15
Pneumatosis in canine gastric dilatation-volvulus syndrome. (15200256)
2004
16
Gastric dilatation-volvulus syndrome in dogs. (14552158)
2003
17
Benefits of prophylactic gastropexy for dogs at risk of gastric dilatation-volvulus. (12941556)
2003
18
Relationship between incidence of gastric dilatation-volvulus and biometeorologic events in a population of military working dogs. (16206779)
2002
19
What is your diagnosis? Gastric dilatation and herniation of the stomach into the caudal region of the thorax. (11700701)
2001
20
Ventral marsupialisation in the treatment of gastric dilatation-volvulus in two dogs. (10879404)
2000
21
Possible involvement of Sarcina ventriculi in canine and equine acute gastric dilatation. (11126583)
2000
22
Small size of food particles and age as risk factors for gastric dilatation volvulus in great danes. (9699253)
1998
23
Multiple risk factors for the gastric dilatation-volvulus syndrome in dogs: a practitioner/owner case-control study. (9138229)
1997
24
Gastric dilatation-volvulus in the dog with histological evidence of preexisting inflammatory bowel disease: a retrospective study of 23 cases. (8784718)
1996
25
Gastric emptying of nondigestible radiopaque markers after circumcostal gastropexy in clinically normal dogs and dogs with gastric dilatation-volvulus. (1456548)
1992
26
The use of retrievable electrodes for recording gastric myoelectric activity after spontaneous gastric dilatation volvulus in dogs. (1424635)
1992
27
Effects of flunixin meglumine on dogs with experimental gastric dilatation-volvulus. (1626380)
1992
28
Dramatic electrocardiographic T-wave changes associated with gastric dilatation. (2376185)
1990
29
Prevention of reperfusion injury in surgically induced gastric dilatation-volvulus in dogs. (2301843)
1990
30
Significance of the Heineke-Mikulicz pyloroplasty in the treatment of gastric dilatation-volvulus. A prospective clinical study. (2929135)
1989
31
Relationship of plasma gastrin immunoreactivity and gastroesophageal sphincter pressure in clinically normal dogs and in dogs with previous gastric dilatation-volvulus. (2782705)
1989
32
Canine gastric dilatation--volvulus update. (2697921)
1989
33
Endoscopic balloon dilatation of benign gastric outlet obstruction. (3140987)
1988
34
Neuropathic gastric dilatation in psittaciformes. (3579790)
1987
35
Adult survival with intrahepatic portal venous gas secondary to acute gastric dilatation, with a review of portal venous gas. (4064538)
1985
36
Acute pancreatitis and gastric dilatation in a patient with anorexia nervosa. (3991401)
1985
37
Acute gastric dilatation following upper gastrointestinal endoscopy. (4006871)
1985
38
Acute gastric dilatation associated with viral hepatitis-A. (6573011)
1983
39
Acute gastric dilatation in nonhuman primates: review and case studies. (6153002)
1982
40
Acid-base and electrolyte values in dogs with acute gastric dilatation-volvulus. (7085476)
1982
41
Gastric dilatation as a complication of bulimia. (6949173)
1982
42
Acute gastric dilatation--volvulus. (6971513)
1981
43
Acute gastric dilatation in common marmosets (Callithrix jacchus). (6281555)
1981
44
Acute gastric dilatation with herniation in a Rhesus monkey. (6767302)
1980
45
Observations on acute gastric dilatation in nonhuman primates. (98666)
1978
46
Acute gastric dilatation associated with gastric volvulus in the guinea pig. (597385)
1977
47
New concepts in the pathogenesis of acute gastric dilatation. (805531)
1975
48
Acute gastric dilatation in anorexia nervosa. (4834098)
1974
49
Pressure injury to the gastric mucosa. Studies on an in vivo model of acute gastric dilatation. (5304828)
1969
50
Acute gastric dilatation; a clinical problem. (13189078)
1954

Genetic Variations for Gastric Dilatation

Expression for genes affiliated with Gastric Dilatation

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

Pathways for genes affiliated with Gastric Dilatation

Sources:
30KEGG, 54Reactome, 38NCBI BioSystems Database
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Pathways related to Gastric Dilatation according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
9.2ARSE, ARSD
2
Hide members
9.2ARSE, ARSD
39.2ARSE, ARSD

Compounds for genes affiliated with Gastric Dilatation

Sources:
45Novoseek, 24HMDB, 29IUPHAR, 11DrugBank
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Compounds related to Gastric Dilatation according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1sulfate45 2410.2ARSE, ARSD
2estrone sulfate45 2410.1ARSE, ARSD
3estrone45 29 11 2411.9ARSE, ARSD

GO Terms for genes affiliated with Gastric Dilatation

Sources:
16Gene Ontology
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Cellular components related to Gastric Dilatation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1lysosomeGO:0057649.1MANBA, ARSD
2endoplasmic reticulum lumenGO:0057888.9ARSE, ARSD

Biological processes related to Gastric Dilatation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1post-translational protein modificationGO:0436879.2ARSE, ARSD
2glycosphingolipid metabolic processGO:0066879.1ARSE, ARSD
3sphingolipid metabolic processGO:0066658.9ARSE, ARSD

Molecular functions related to Gastric Dilatation according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1arylsulfatase activityGO:0040659.2ARSE, ARSD

Products for genes affiliated with Gastric Dilatation

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gastric Dilatation

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet