MCID: GST007
MIFTS: 37

Gastric Dilatation

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Dilatation

MalaCards integrated aliases for Gastric Dilatation:

Name: Gastric Dilatation 12 42 14 69
Stomach Dilatation 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3229
MeSH 42 D013271
UMLS 69 C0038353

Summaries for Gastric Dilatation

MalaCards based summary : Gastric Dilatation, also known as stomach dilatation, is related to anorexia nervosa and muscle disorders. An important gene associated with Gastric Dilatation is MANBA (Mannosidase Beta), and among its related pathways/superpathways are Glycosaminoglycan metabolism and Sphingolipid metabolism. The drugs Citalopram and Reboxetine have been mentioned in the context of this disorder. Affiliated tissues include liver, lung and breast, and related phenotype is renal/urinary system.

Related Diseases for Gastric Dilatation

Diseases related to Gastric Dilatation via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 63)
id Related Disease Score Top Affiliating Genes
1 anorexia nervosa 10.1
2 muscle disorders 10.0 ARSH GLB1
3 hypogonadotropic hypogonadism 16 with or without anosmia 10.0 GLB1 MANBA
4 superior mesenteric artery syndrome 9.9
5 eating disorder 9.9
6 hepatitis 9.9
7 bulimia nervosa 9.9
8 ischemia 9.9
9 duodenitis 9.9
10 ciliary dyskinesia, primary, 29 9.8 ARSB ARSH
11 pancreatitis 9.8
12 muscular dystrophy 9.8
13 intellectual developmental disorder with dysmorphic facies and ptosis 9.8 ARSB ARSH
14 obesity 9.8
15 pyloric stenosis 9.8
16 acute pancreatitis 9.8
17 compartment syndrome 9.8
18 microcephaly 16, primary, autosomal recessive 9.7 ARSB ARSH
19 prader-willi syndrome 9.7
20 gastroschisis 9.7
21 morbid obesity 9.7
22 gastric ulcer 9.7
23 respiratory failure 9.7
24 autonomic neuropathy 9.7
25 duodenal ulcer 9.7
26 cerebritis 9.7
27 laryngitis 9.7
28 gastritis 9.7
29 peritonitis 9.7
30 intestinal obstruction 9.7
31 neuropathy 9.7
32 progressive muscular dystrophy 9.7
33 bacteremia 9.5
34 multiple myeloma 9.5
35 duchenne muscular dystrophy 9.5
36 duodenal atresia 9.5
37 cerebral palsy 9.5
38 inflammatory bowel disease 9.5
39 atrioventricular block 9.5
40 limb ischemia 9.5
41 cardiac arrest 9.5
42 rickets 9.5
43 megacolon 9.5
44 pulmonary edema 9.5
45 diabetic autonomic neuropathy 9.5
46 gastroparesis 9.5
47 bronchopneumonia 9.5
48 hepatitis a 9.5
49 hypertrophic pyloric stenosis 9.5
50 hiatus hernia 9.5

Graphical network of the top 20 diseases related to Gastric Dilatation:



Diseases related to Gastric Dilatation

Symptoms & Phenotypes for Gastric Dilatation

MGI Mouse Phenotypes related to Gastric Dilatation:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 8.92 ARSB GLB1 ITGB4 MANBA

Drugs & Therapeutics for Gastric Dilatation

Drugs for Gastric Dilatation (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 132)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Citalopram Approved Phase 4 59729-33-8 2771
2
Reboxetine Approved, Investigational Phase 4 98769-81-4, 71620-89-8 123628 65856
3
Chlorhexidine Approved, Vet_approved Phase 4 55-56-1 9552079 2713
4
Doxycycline Approved, Investigational, Vet_approved Phase 4 564-25-0 54671203
5
Methylene blue Investigational Phase 4 61-73-4
6 Adrenergic Agents Phase 4,Phase 3
7 Antidepressive Agents Phase 4
8 Antidepressive Agents, Second-Generation Phase 4
9 Antiparkinson Agents Phase 4
10 Autonomic Agents Phase 4,Phase 2
11 Cholinergic Agents Phase 4
12 Cholinergic Antagonists Phase 4
13 Muscarinic Antagonists Phase 4
14 Neurotransmitter Agents Phase 4,Phase 3,Phase 2
15 Neurotransmitter Uptake Inhibitors Phase 4
16 Parasympatholytics Phase 4
17 Peripheral Nervous System Agents Phase 4,Phase 2
18 Psychotropic Drugs Phase 4
19
Serotonin Phase 4,Phase 3 50-67-9 5202
20 Serotonin Agents Phase 4,Phase 3
21 Serotonin Uptake Inhibitors Phase 4
22 Anesthetics Phase 4
23 Anesthetics, Local Phase 4
24 Anti-Infective Agents Phase 4,Phase 2,Phase 3
25 Anti-Infective Agents, Local Phase 4
26 Chlorhexidine gluconate Phase 4
27 Disinfectants Phase 4
28 Anticholesteremic Agents Phase 4
29 Antimetabolites Phase 4
30 Atorvastatin Calcium Phase 4 134523-03-8
31 Calcium, Dietary Phase 4
32 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
33 Hypolipidemic Agents Phase 4
34 Lipid Regulating Agents Phase 4
35 Rosuvastatin Calcium Phase 4 147098-20-2
36 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
37 Antibiotics, Antitubercular Phase 4
38 Antimalarials Phase 4
39 Antiparasitic Agents Phase 4
40 Antiprotozoal Agents Phase 4
41 Cola Nutraceutical Phase 4
42
Erythromycin Approved, Vet_approved Phase 2, Phase 3 114-07-8 12560
43
Midazolam Approved, Illicit Phase 3 59467-70-8 4192
44
Nadolol Approved Phase 3 42200-33-9 39147
45
Folic Acid Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 59-30-3 6037
46
Riboflavin Approved, Nutraceutical, Vet_approved Phase 2, Phase 3 83-88-5 493570
47 Dermatologic Agents Phase 2, Phase 3
48 Micronutrients Phase 2, Phase 3
49 Photosensitizing Agents Phase 2, Phase 3
50 Trace Elements Phase 2, Phase 3

Interventional clinical trials:

(show top 50) (show all 92)

id Name Status NCT ID Phase Drugs
1 Effect of Invasive and Non Invasive Mechanical Ventilation on Feeding Delivery in COPD Elderly Patients Unknown status NCT00417755 Phase 4
2 Banded Versus Conventional Laparoscopic Roux-en-Y (GABY) Unknown status NCT01015469 Phase 4
3 Effect of Escitalopram vs. Reboxetine on Gastro-intestinal Sensitivity of Patients With Major Depressive Disorder Unknown status NCT00209807 Phase 4 escitalopram;Reboxetine
4 Personalized Peroral Endoscopic Myotomy for Achalasia Unknown status NCT01570621 Phase 4
5 Comparison of Laryngeal Mask Airway Supreme and Endotracheal Tube In Patients Undergoing Gynecological Laparoscopy Surgery Completed NCT02127632 Phase 4
6 Short Term Statin Treatment and Endothelial Dysfunction Due to Ischemia and Reperfusion Injury Completed NCT00987974 Phase 4 rosuvastatin;atorvastatin 3 days;placebo;rosuvastatin 7 days;atorvastatin 7 days;placebo 7 days
7 Do Nasogastric Tubes After Cardiac Surgery Reduce Nausea and Vomiting Completed NCT00193999 Phase 4
8 Impact of Visceral Osteopathic Treatment on Meconium Evacuation in Preterm Infants Completed NCT02140710 Phase 4
9 Time Interval for Endoscopic Variceal Ligation Completed NCT01291277 Phase 4
10 Serum Levels of Doxycycline at the Time of Abortion With Two Dosing Regimens Completed NCT00177333 Phase 4 Doxycycline
11 Gastric vs Jejunal Feeding in Diabetic Gastroparesis Withdrawn NCT00944593 Phase 4
12 Probiotics in Patients With Moderate-to-severe Distention/ Bloating From Systemic Sclerosis Withdrawn NCT01497743 Phase 4 Lactobacillus
13 Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs Unknown status NCT01081561 Phase 2, Phase 3 Riboflavin
14 Endoscopic Band Ligation Versus Argon Plasma Coagulation for the Treatment of Gastric Antral Vascular Ectasia: a Randomized Clinical Trial Completed NCT01601639 Phase 3
15 The Effects of Tegaserod on Mechanical Sensitivity of the Esophagus and Stomach in Patients With Heartburn and Dyspepsia. Completed NCT00171457 Phase 3 Tegaserod
16 Cyrotherapy vs. APC in GAVE Completed NCT00587405 Phase 2, Phase 3
17 Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility Completed NCT01379183 Phase 2, Phase 3 Erythromycin;Placebo
18 Impact of Gastric Bypass Surgery on Risk of CVD in Type 2 Diabetes Mellitus Completed NCT00444392 Phase 3
19 Acu-TENS for Pain Relief During Colonoscopy Completed NCT01751815 Phase 3
20 Noninvasive Continuous Positive Airway Pressure (NCPAP) in Children Completed NCT01242150 Phase 3
21 Electroacupuncture for Postoperative Ileus After Laparoscopic Colorectal Surgery Completed NCT00464425 Phase 3
22 Incisionless Treatment for Patients With Inadequate Weight Loss Following Roux-en-Y Gastric Bypass Terminated NCT00394212 Phase 3
23 StomaphyX Versus Sham for Revisional Surgery in Post-Roux-en-Y Patients to Reduce Regained Weight Terminated NCT00939055 Phase 2, Phase 3
24 Beta Blockers Versus Variceal Band Ligation and Beta Blockers for Primary Prophylaxis of Variceal Bleeding Terminated NCT00409084 Phase 3
25 An Exploratory Study Examining The Effects Of Taking GW679769 Once-Daily For 4 Days In Patients With Functional Dyspepsia Completed NCT00358410 Phase 2 GW679769 oral tablets;Placebo
26 Evaluation of the Safety and Effectiveness of Stomaphyx for Transoral Incisionless Reduction of the Enlarged Gastric Pouch and Stoma Completed NCT01025076 Phase 2
27 Long-term Effects of Thalidomide for Recurrent Gastrointestinal Bleeding Due to Vascular Malformation Completed NCT00964496 Phase 2 Thalidomide;Iron
28 SAFEstart Feeding Intolerance Study Phase II Completed NCT00331201 Phase 2 SAFEstart
29 Uncut Roux-en-Y Gastrojejunostomy for Early Gastric Cancer Patients Recruiting NCT02644148 Phase 2
30 A Safety and Efficacy Trial of Circumferential Anal Canal Radiofrequency Ablation for High-Grade Anal Intraepithelial Neoplasia Using the BARRX™ Anorectal Wand Recruiting NCT03302858 Phase 2
31 Gastric Sleeve Pilot Study in Morbidly Obese Undergoing Liver Transplantation Completed NCT02068872 Phase 1
32 Post-marketing Surveillance Study of A.M.I. Protector Adjustable Gastric Band Unknown status NCT01752829
33 Banded Versus Non-banded Roux-en-Y Gastric Bypass Unknown status NCT01078181
34 A Randomized Comparison of Laparoscopic Myotomy and Pneumatic Dilatation for Achalasia Unknown status NCT00188344
35 Effect of BAriatric Surgery Versus Optimal Medical Therapy on Cardiovascular Health and Atherosclerosis in Obese, Type II Diabetic Patients Unknown status NCT02331420
36 Pyloric Sphincter Pressure and Geometry Assessment Using EndoFlip Unknown status NCT02446119
37 Is Nasogastric Tube Necessary After Pancreaticoduodenectomy? Unknown status NCT01991392
38 Is Nasogastric Tube Necessary After Pancreaticoduodenectomy? Unknown status NCT01966406
39 Heating Precondition of Streamlined Liner of the Pharynx Airway Decrease the Incidence of Sore Throat Unknown status NCT02539485
40 Evaluation of Feeding Intolerance in Premature Infants Using Near Infrared Spectroscopy Unknown status NCT02534090
41 Gastric Volumetry by Gastric Tomodensitometry With Gas Completed NCT01963637
42 Esophageal Dysmotility and Dilatation After Laparoscopic Gastric Banding Completed NCT01234428
43 Endolumenal Gastric Pouch and Gastrojejunal Anastomosis Reduction Completed NCT01003743
44 Unnecessary Gastric Decompression in Distal Elective Bowel Anastomoses in Children. A Randomized Study Completed NCT01011023
45 MRI Study of Stomach Volumes and Satiety Completed NCT01690182
46 Endoscopic Suturing System for Tissue Apposition Completed NCT00495222
47 Feasibility Trial to Evaluate the Ability of the SuMO Tissue Access and Resection System Completed NCT01322737
48 Brain Activity and Hormonal Changes During Food Administration Completed NCT01644539
49 Structure and Function of the Gastro-esophageal Junction Completed NCT01053585 Baclofen;Placebo
50 INtestinal Failure, multiPle Organ Failure ANd CItrulline Assessment Completed NCT02520440

Search NIH Clinical Center for Gastric Dilatation

Cochrane evidence based reviews: gastric dilatation

Genetic Tests for Gastric Dilatation

Anatomical Context for Gastric Dilatation

MalaCards organs/tissues related to Gastric Dilatation:

39
Liver, Lung, Breast, Endothelial, Brain, Testes, Colon

Publications for Gastric Dilatation

Articles related to Gastric Dilatation:

(show top 50) (show all 328)
id Title Authors Year
1
Gastric Dilatation Associated with Gastric Colonization with Sarcina-like Bacteria in a Cat with Chronic Enteritis. ( 28892423 )
2017
2
Associations between gastric dilatation-volvulus in Great Danes and specific alleles of the canine immune-system genes DLA88, DRB1, and TLR5. ( 28738011 )
2017
3
Gastric Dilatation and Abdominal Compartment Syndrome in a Child with Prader-Willi Syndrome. ( 28588153 )
2017
4
Acute massive gastric dilatation causing ischaemic necrosis and perforation of the stomach. ( 28619737 )
2017
5
Modified tube gastropexy using a mushroom-tipped silicone catheter for management of gastric dilatation-volvulus in dogs. ( 28160305 )
2017
6
GASTRIC DILATATION VOLVULUS IN ADULT MANED WOLVES (CHRYSOCYON BRACHYURUS). ( 28749303 )
2017
7
Pyloric localisation in 57 dogs of breeds susceptible to gastric dilatation-volvulus in the UK using computed tomography. ( 27784838 )
2016
8
Portal vein gas secondary to acute non-obstructive gastric dilatation. ( 27916447 )
2016
9
Temporary percutaneous T-fastener gastropexy and continuous decompressive gastrostomy in dogs with experimentally induced gastric dilatation. ( 27347832 )
2016
10
Binge Eating Leading to Acute Gastric Dilatation, Ischemic Necrosis and Rupture -A Case Report. ( 27134932 )
2016
11
Use of a venting PEG tube in the management of recurrent acute gastric dilatation associated with Prader-Willi syndrome. ( 26763981 )
2016
12
Acute gastric dilatation in a bulimic patient. ( 26975234 )
2016
13
Unanswered questions on gastric dilatation/volvulus and gastropexy. ( 27980146 )
2016
14
Dobutamine stress echocardiography resulting in acute gastric dilatation and pneumoporta. ( 27388544 )
2016
15
Unexpected Death Due to Acute Gastric Dilatation and Gastric Necrosis in an 11-Year-Old Boy. ( 27164319 )
2016
16
Gastric dilatation and intestinal obstruction mimicking acute coronary syndrome with dynamic electrocardiographic changes. ( 27899069 )
2016
17
Massive gastric dilatation: the radiological picture of eating disorder. ( 27041386 )
2016
18
Severe Acute Postoperative Gastric Dilatation. ( 26158257 )
2015
19
Extraordinary cause of acute gastric dilatation and hepatic portal venous gas: Chronic use of synthetic cannabinoid. ( 26457032 )
2015
20
C-reactive protein and high mobility group box 1 in dogs with gastric dilatation and volvulus. ( 26088834 )
2015
21
Severe gastric dilatation due to superior mesenteric artery syndrome in anorexia nervosa. ( 25639251 )
2015
22
Acute gastric dilatation in the context of bulimia nervosa. ( 26334471 )
2015
23
Acute gastric dilatation causing fatal outcome in a young female with eating disorder: a case report. ( 25844140 )
2015
24
Suspicion of superior mesenteric artery syndrome in a patient with severe gastric dilatation after catheter ablation. ( 25786450 )
2015
25
Gastrojejunostomy for pyloric stenosis after acute gastric dilatation due to overeating. ( 25663789 )
2015
26
Young Adult With Abdominal Pain. Gastric dilatation caused by anorexia nervosa. ( 26497441 )
2015
27
Acute massive gastric dilatation with abdominal compartment syndrome in a patient with bulimia nervosa. ( 26077071 )
2015
28
Gastric dilatation volvulus: a retrospective study of 203 dogs with ventral midline gastropexy. ( 26459100 )
2015
29
Life-threatening acute gastric dilatation with aorta compression in a 3-year-old child. ( 26387581 )
2015
30
What Is Your Diagnosis? Gastric dilatation-volvulus. ( 26594805 )
2015
31
Delayed Pneumoperitoneum and Acute Pulmonary Edema Secondary to Acute Gastric Dilatation. ( 26668807 )
2015
32
Hemostatic variables, plasma lactate concentration, and inflammatory biomarkers in dogs with gastric dilatation-volvulus. ( 26568318 )
2015
33
Acute gastric dilatation in the context of bulimia nervosa. ( 26177084 )
2015
34
Postoperative management of dogs with gastric dilatation and volvulus. ( 25496926 )
2014
35
Cardiovascular and systemic effects of gastric dilatation and volvulus in dogs. ( 25496923 )
2014
36
Occurrence and recurrence of gastric dilatation with or without volvulus after incisional gastropexy. ( 25320388 )
2014
37
Recurrent gastric dilatation and intestinal dysmotility possibly resulting from autonomic neuropathy in a Great Dane. ( 24659724 )
2014
38
Treatment of gastric dilatation in rabbits. ( 25103747 )
2014
39
Gastropexy for prevention of gastric dilatation-volvulus in dogs: history and techniques. ( 25496925 )
2014
40
Massive gastric dilatation in bulimic patient. ( 25223115 )
2014
41
Treatment of gastric dilatation in rabbits. ( 25103746 )
2014
42
Gastric dilatation and volvulus in a brachycephalic dog with hiatal hernia. ( 24871205 )
2014
43
Acute gastric dilatation causing acute limb ischemia in an anorexia nervosa patient. ( 24560015 )
2014
44
Gastric Dilatation and Volvulus in a Red Panda (Ailurus fulgens). ( 24467661 )
2014
45
Acute gastric dilatation due to a superior mesenteric artery syndrome: an autopsy case. ( 24555911 )
2014
46
Prolonged idiopathic gastric dilatation following revascularization for chronic mesenteric ischemia. ( 24975870 )
2014
47
A case report of percutaneous endoscopic gastrostomy left-side gastropexy to resolve a recurrent gastric dilatation in a dog previously treated with right-side gastropexy for gastric dilatation volvulus. ( 25813852 )
2014
48
Abdominal aortic occlusion and vascular compromise secondary to acute gastric dilatation in a patient with bulimia. ( 25350169 )
2014
49
The relationship between gastrointestinal motility and gastric dilatation-volvulus in dogs. ( 25496922 )
2014
50
Inherited and predisposing factors in the development of gastric dilatation volvulus in dogs. ( 25496921 )
2014

Variations for Gastric Dilatation

Expression for Gastric Dilatation

Search GEO for disease gene expression data for Gastric Dilatation.

Pathways for Gastric Dilatation

GO Terms for Gastric Dilatation

Cellular components related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ficolin-1-rich granule lumen GO:1904813 9.26 ARSB GLB1
2 azurophil granule lumen GO:0035578 9.16 ARSB GLB1
3 lysosome GO:0005764 9.13 ARSB GLB1 MANBA
4 lysosomal lumen GO:0043202 8.8 ARSB GLB1 MANBA

Biological processes related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.33 ARSB GLB1 MANBA
2 glycosphingolipid metabolic process GO:0006687 9.13 ARSB ARSH GLB1
3 metabolic process GO:0008152 9.02 ARSB ARSH GLB1 MANBA UMPS

Molecular functions related to Gastric Dilatation according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 hydrolase activity, acting on glycosyl bonds GO:0016798 9.16 GLB1 MANBA
2 sulfuric ester hydrolase activity GO:0008484 8.96 ARSB ARSH
3 arylsulfatase activity GO:0004065 8.62 ARSB ARSH

Sources for Gastric Dilatation

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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