MCID: GST064
MIFTS: 33

Gastric Outlet Obstruction malady

Gastrointestinal diseases category

Aliases & Classifications for Gastric Outlet Obstruction

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Gastric Outlet Obstruction, Aliases & Descriptions:

Name: Gastric Outlet Obstruction 11 60


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Summaries for Gastric Outlet Obstruction

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Wikipedia:63 Gastric outlet obstruction (often abbreviated as GOO) is a medical condition where there is an... more...

MalaCards based summary: Gastric Outlet Obstruction is related to duodenitis and peptic ulcer disease. An important gene associated with Gastric Outlet Obstruction is ATP4A (ATPase, H+/K+ exchanging, alpha polypeptide), and among its related pathways are Salivary secretion and Gastrin-CREB signalling pathway via PKC and MAPK. The compounds esomeprazole and rabeprazole have been mentioned in the context of this disorder. Affiliated tissues include small intestine, pancreas and liver, and related mouse phenotype digestive/alimentary.

Related Diseases for Gastric Outlet Obstruction

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Graphical network of the top 20 diseases related to Gastric Outlet Obstruction:



Diseases related to gastric outlet obstruction

Symptoms for Gastric Outlet Obstruction

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Drugs & Therapeutics for Gastric Outlet Obstruction

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Drug clinical trials:

Search ClinicalTrials for Gastric Outlet Obstruction

Search NIH Clinical Center for Gastric Outlet Obstruction

Genetic Tests for Gastric Outlet Obstruction

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Anatomical Context for Gastric Outlet Obstruction

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MalaCards organs/tissues related to Gastric Outlet Obstruction:

31
Small intestine, Pancreas, Liver, Spleen, Testes, Breast, Colon, Kidney, Skin, Myeloid

Animal Models for Gastric Outlet Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Gastric Outlet Obstruction:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6GAST, ATP12A, ATP4A

Publications for Gastric Outlet Obstruction

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Articles related to Gastric Outlet Obstruction:

(show top 50)    (show all 530)
idTitleAuthorsYear
1
Elastofibroma of the pylorus presenting as gastric outlet obstruction: a case report and review of literature. (25078537)
2014
2
Gastric leiomyosarcoma as a rare cause of gastric outlet obstruction and perforation: a case report. (25069607)
2014
3
Gastrointestinal: gastric outlet obstruction and air pancreatogram in the setting of recurrent acute pancreatitis. (25040618)
2014
4
A Multicenter Randomized Controlled Trial of Malignant Gastric Outlet Obstruction: Tailored Partially Covered Stents (Placed Fluoroscopically) versus Standard Uncovered Stents (Placed Endoscopically). (25610459)
2014
5
Gastric outlet obstruction: Better seen than felt. (25668177)
2014
6
Gastric heterotopic pancreas abscess leading to gastric outlet obstruction. (23948200)
2013
7
Long-term outcome of palliative therapy for gastric outlet obstruction caused by unresectable gastric cancer in patients with good performance status: endoscopic stenting versus surgery. (23522025)
2013
8
Duplication cyst of pyloric canal: a rare cause of pediatric gastric outlet obstruction: rare case report. (24426605)
2013
9
First Reported Case of Intentional Use of a Duodenal Stent to Treat Gastric Outlet Obstruction Prior to Pancreaticoduodenectomy in a Patient with Pancreatic Cancer. (24114048)
2013
10
Large-Diameter (30-35 mm) Pneumatic Balloon Dilatation of The Pylorus In Patients With Gastric Outlet Obstruction Symptoms After Esophagectomy. (23820681)
2013
11
Bouveret's syndrome: successful endoscopic treatment of gastric outlet obstruction caused by an impacted gallstone. (22414360)
2012
12
Clinical outcomes of secondary stent-in-stent self-expanding metal stent placement for primary stent malfunction in malignant gastric outlet obstruction. (22835857)
2012
13
Surgical management of benign gastric outlet obstruction in the elderly. (22683983)
2012
14
Endoscopic balloon dilatation without fluoroscopy for treating gastric outlet obstruction because of benign etiologies. (21052720)
2011
15
Endoscopic management of multiple large antral hyperplastic polyps causing gastric outlet obstruction. (21834480)
2011
16
Safety and efficacy of a new non-foreshortening nitinol stent in malignant gastric outlet obstruction (DUONITI study): a prospective, multicenter study. (21656455)
2011
17
Development of a duodenal gallstone ileus with gastric outlet obstruction (Bouveret syndrome) four months after successful treatment of symptomatic gallstone disease with cholecystitis and cholangitis: a case report. (21092262)
2010
18
A systematic review of methods to palliate malignant gastric outlet obstruction. (19551436)
2010
19
Endoscopic balloon dilation in caustic-induced chronic gastric outlet obstruction. (19136104)
2009
20
Bezoar in gastro-jejunostomy presenting with symptoms of gastric outlet obstruction: a case report and review of the literature. (18831730)
2008
21
Gastric carcinoid presented as gastric outlet obstruction. (20085045)
2008
22
Post-esophagectomy gastric outlet obstruction: role of pyloromyotomy and management with endoscopic pyloric dilatation. (17166733)
2007
23
Bouveret's syndrome: management and strategy of a rare cause of gastric outlet obstruction. (17429202)
2007
24
Morbidity-associated factors after gastrojejunostomy for malignant gastric outlet obstruction. (17939415)
2007
25
Clinical challenges and images in GI. Gallstone impacted in duodenum causing gastric outlet obstruction (Bouveret syndrome). (17919482)
2007
26
Gastric outlet obstruction. (18067699)
2007
27
Gastrointestinal neurofibromatosis: an unusual cause of gastric outlet obstruction. (16022006)
2005
28
Ectopic pancreas as a cause of gastric outlet obstruction in an infant. (15627663)
2004
29
Vagotomy and gastrojejunostomy for benign gastric outlet obstruction. (15630940)
2004
30
Corrosive-induced gastric outlet obstruction. (14703606)
2003
31
Multiple giant duodenal gallstones causing gastric outlet obstruction: Bouveret's minefield revisited. (14696446)
2003
32
An unusual cause of gastric outlet obstruction: a case report. (14603827)
2003
33
Gastric outlet obstruction caused by a heterotopic pancreas in a pregnant woman: report of a case. (14669092)
2003
34
Gastric outlet obstruction by an antral mucosal diaphragm: a case of a congenital anomaly revealed by an acquired disease. (14618524)
2003
35
A rare cause of gastric outlet obstruction in the newborn: Pyloric ectopic pancreas. (11782002)
2002
36
Gastric outlet obstruction following surgery for morbid obesity: efficacy of fluoroscopically guided balloon dilation. (11756707)
2002
37
Clinical experience in the treatment of ulcer-induced gastric outlet obstruction in seven children. (11021004)
2000
38
Gastric outlet obstruction due to benign dilatation of gallbladder. (11147955)
2000
39
Gastric outlet obstruction as a late complication of formaldehyde ingestion: a case report. (10445565)
1999
40
Granulomatous gastritis presenting as gastric outlet obstruction: a case report. (9789139)
1998
41
Palliation of malignant gastric outlet obstruction using an endoscopically placed Wallstent. (9540881)
1998
42
Gastric lactobezoar: a rare cause of gastric outlet obstruction. (9291515)
1997
43
Resolution of gastric outlet obstruction after eradication of Helicobacter pylori. (8583113)
1995
44
Leiomyoblastoma causing acute gastric outlet obstruction in an infant. (7807332)
1994
45
Prospective randomized study comparing three surgical techniques for the treatment of gastric outlet obstruction secondary to duodenal ulcer. (8101050)
1993
46
Endoscopic management of gastric outlet obstruction. (1906031)
1991
47
Management of gastric outlet obstruction caused by ovarian cancer. (2013454)
1991
48
Carcinoid tumour presenting as recurrent gastric outlet obstruction: a case of long-term survival. (3602991)
1987
49
Preliminary experience with hydrostatic balloon dilation of gastric outlet obstruction. (3710101)
1986
50
Gastric outlet obstruction secondary to a gallstone (Bouveret's syndrome) (4020089)
1985

Variations for Gastric Outlet Obstruction

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Expression for genes affiliated with Gastric Outlet Obstruction

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Search GEO for disease gene expression data for Gastric Outlet Obstruction.

Pathways for genes affiliated with Gastric Outlet Obstruction

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Pathways related to Gastric Outlet Obstruction according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4GAST, ATP4A
2
Show member pathways
9.3GAST, MLN
3
Show member pathways
9.1ATP12A, ATP4A
4
Show member pathways
calcium transport I36
9.1ATP12A, ATP4A

Compounds for genes affiliated with Gastric Outlet Obstruction

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Compounds related to Gastric Outlet Obstruction according to GeneCards Suite gene sharing:

(show all 26)
idCompoundScoreTop Affiliating Genes
1esomeprazole43 49 1211.8GAST, ATP4A
2rabeprazole43 49 24 1212.8GAST, ATP4A
3lansoprazole43 49 24 1212.8GAST, ATP4A
4trimebutine439.7MLN, GAST
5lafutidine439.7GAST, MLN
6bethanechol43 28 1211.7MLN, GAST
7domperidone43 28 1211.7GAST, MLN
8oxyntomodulin43 5910.6MLN, GAST
9ondansetron49 43 24 1212.6GAST, MLN
10ranitidine43 28 24 1212.6GAST, MLN
11famotidine43 2 24 1212.6GAST, MLN
12erythromycin43 2 49 1212.6GAST, MLN
13octreotide43 59 28 1212.6GAST, MLN
14atropine43 28 1211.6MLN, GAST
15acetaminophen43 2 49 24 1213.5GAST, MLN
16nifedipine43 28 49 1212.5GAST, MLN
175-hydroxytryptamine439.5MLN, GAST
18thyroxine43 2410.4GAST, MLN
19acth439.4GAST, MLN
20histamine43 28 2411.3MLN, GAST
21acetylcholine43 49 28 24 1213.2GAST, MLN
22omeprazole43 49 28 24 1213.2GAST, ATP4A, MLN
23potassium43 24 1211.1ATP12A, ATP4A
24pantoprazole43 49 24 1212.0GAST, ATP12A, ATP4A
25Phosphate248.8ATP12A, ATP4A
26hydrogen43 249.8MLN, ATP12A, GAST

GO Terms for genes affiliated with Gastric Outlet Obstruction

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Biological processes related to Gastric Outlet Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled receptor signaling pathwayGO:00071869.3GAST, MLN
2ATP biosynthetic processGO:00067549.0ATP12A, ATP4A
3ion transmembrane transportGO:00342208.8ATP12A, ATP4A

Molecular functions related to Gastric Outlet Obstruction according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:00051799.3GAST, MLN
2hydrogen:potassium-exchanging ATPase activityGO:00089008.8ATP12A, ATP4A

Products for genes affiliated with Gastric Outlet Obstruction

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Sources for Gastric Outlet Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet