MCID: GST064
MIFTS: 39

Gastric Outlet Obstruction malady

Gastrointestinal diseases category
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Summaries for Gastric Outlet Obstruction

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Fully expand this MalaCard
Wikipedia:65 Gastric outlet obstruction (often abbreviated as GOO) is a medical condition where there is an... more...

MalaCards based summary: Gastric Outlet Obstruction is related to duodenitis and peptic ulcer disease. An important gene associated with Gastric Outlet Obstruction is ATP4A (ATPase, H+/K+ exchanging, alpha polypeptide), and among its related pathways are Salivary secretion and Gastrin-CREB signalling pathway via PKC and MAPK. The compounds esomeprazole and rabeprazole have been mentioned in the context of this disorder. Affiliated tissues include small intestine, pancreas and liver, and related mouse phenotype digestive/alimentary.

Aliases & Classifications for Gastric Outlet Obstruction

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Gastric Outlet Obstruction, Aliases & Descriptions:

Name: Gastric Outlet Obstruction 10 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Related Diseases for Gastric Outlet Obstruction

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Graphical network of the top 20 diseases related to Gastric Outlet Obstruction:



Diseases related to gastric outlet obstruction

Symptoms for Gastric Outlet Obstruction

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Drugs & Therapeutics for Gastric Outlet Obstruction

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Drug clinical trials:

Search ClinicalTrials for Gastric Outlet Obstruction

Search NIH Clinical Center for Gastric Outlet Obstruction

Genetic Tests for Gastric Outlet Obstruction

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Anatomical Context for Gastric Outlet Obstruction

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MalaCards organs/tissues related to Gastric Outlet Obstruction:

32
Small intestine, Pancreas, Liver, Spleen, Testes, Breast, Colon, Kidney, Skin, Myeloid

Animal Models for Gastric Outlet Obstruction or affiliated genes

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MGI Mouse Phenotypes related to Gastric Outlet Obstruction:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.6GAST, ATP12A, ATP4A

Publications for Gastric Outlet Obstruction

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Articles related to Gastric Outlet Obstruction:

(show top 50)    (show all 509)
idTitleAuthorsYear
1
Elastofibroma of the pylorus presenting as gastric outlet obstruction: a case report and review of literature. (25078537)
2014
2
Gastric leiomyosarcoma as a rare cause of gastric outlet obstruction and perforation: a case report. (25069607)
2014
3
Gastrointestinal: gastric outlet obstruction and air pancreatogram in the setting of recurrent acute pancreatitis. (25040618)
2014
4
Gastric heterotopic pancreas abscess leading to gastric outlet obstruction. (23948200)
2013
5
Long-term outcome of palliative therapy for gastric outlet obstruction caused by unresectable gastric cancer in patients with good performance status: endoscopic stenting versus surgery. (23522025)
2013
6
Duplication cyst of pyloric canal: a rare cause of pediatric gastric outlet obstruction: rare case report. (24426605)
2013
7
First Reported Case of Intentional Use of a Duodenal Stent to Treat Gastric Outlet Obstruction Prior to Pancreaticoduodenectomy in a Patient with Pancreatic Cancer. (24114048)
2013
8
Large-Diameter (30-35 mm) Pneumatic Balloon Dilatation of The Pylorus In Patients With Gastric Outlet Obstruction Symptoms After Esophagectomy. (23820681)
2013
9
Bouveret's syndrome: successful endoscopic treatment of gastric outlet obstruction caused by an impacted gallstone. (22414360)
2012
10
Clinical outcomes of secondary stent-in-stent self-expanding metal stent placement for primary stent malfunction in malignant gastric outlet obstruction. (22835857)
2012
11
Surgical management of benign gastric outlet obstruction in the elderly. (22683983)
2012
12
Endoscopic balloon dilatation without fluoroscopy for treating gastric outlet obstruction because of benign etiologies. (21052720)
2011
13
Endoscopic management of multiple large antral hyperplastic polyps causing gastric outlet obstruction. (21834480)
2011
14
Safety and efficacy of a new non-foreshortening nitinol stent in malignant gastric outlet obstruction (DUONITI study): a prospective, multicenter study. (21656455)
2011
15
Development of a duodenal gallstone ileus with gastric outlet obstruction (Bouveret syndrome) four months after successful treatment of symptomatic gallstone disease with cholecystitis and cholangitis: a case report. (21092262)
2010
16
A systematic review of methods to palliate malignant gastric outlet obstruction. (19551436)
2010
17
Endoscopic balloon dilation in caustic-induced chronic gastric outlet obstruction. (19136104)
2009
18
Bezoar in gastro-jejunostomy presenting with symptoms of gastric outlet obstruction: a case report and review of the literature. (18831730)
2008
19
Gastric carcinoid presented as gastric outlet obstruction. (20085045)
2008
20
Post-esophagectomy gastric outlet obstruction: role of pyloromyotomy and management with endoscopic pyloric dilatation. (17166733)
2007
21
Bouveret's syndrome: management and strategy of a rare cause of gastric outlet obstruction. (17429202)
2007
22
Morbidity-associated factors after gastrojejunostomy for malignant gastric outlet obstruction. (17939415)
2007
23
Clinical challenges and images in GI. Gallstone impacted in duodenum causing gastric outlet obstruction (Bouveret syndrome). (17919482)
2007
24
Gastric outlet obstruction. (18067699)
2007
25
Gastrointestinal neurofibromatosis: an unusual cause of gastric outlet obstruction. (16022006)
2005
26
Ectopic pancreas as a cause of gastric outlet obstruction in an infant. (15627663)
2004
27
Vagotomy and gastrojejunostomy for benign gastric outlet obstruction. (15630940)
2004
28
Gastric outlet obstruction secondary to linitis plastica of the stomach as shown on transabdominal sonography. (15292571)
2004
29
Corrosive-induced gastric outlet obstruction. (14703606)
2003
30
Multiple giant duodenal gallstones causing gastric outlet obstruction: Bouveret's minefield revisited. (14696446)
2003
31
An unusual cause of gastric outlet obstruction: a case report. (14603827)
2003
32
Gastric outlet obstruction caused by a heterotopic pancreas in a pregnant woman: report of a case. (14669092)
2003
33
A rare cause of gastric outlet obstruction in the newborn: Pyloric ectopic pancreas. (11782002)
2002
34
Gastric outlet obstruction following surgery for morbid obesity: efficacy of fluoroscopically guided balloon dilation. (11756707)
2002
35
Clinical experience in the treatment of ulcer-induced gastric outlet obstruction in seven children. (11021004)
2000
36
Gastric outlet obstruction due to benign dilatation of gallbladder. (11147955)
2000
37
Gastric outlet obstruction as a late complication of formaldehyde ingestion: a case report. (10445565)
1999
38
Granulomatous gastritis presenting as gastric outlet obstruction: a case report. (9789139)
1998
39
Palliation of malignant gastric outlet obstruction using an endoscopically placed Wallstent. (9540881)
1998
40
Gastric lactobezoar: a rare cause of gastric outlet obstruction. (9291515)
1997
41
Re: W. de Boer: Gastric outlet obstruction and Helicobacter pylori. (9317100)
1997
42
Endotherapy for gastric outlet obstruction. (8635720)
1996
43
Resolution of gastric outlet obstruction after eradication of Helicobacter pylori. (8583113)
1995
44
Leiomyoblastoma causing acute gastric outlet obstruction in an infant. (7807332)
1994
45
Prospective randomized study comparing three surgical techniques for the treatment of gastric outlet obstruction secondary to duodenal ulcer. (8101050)
1993
46
Endoscopic management of gastric outlet obstruction. (1906031)
1991
47
Management of gastric outlet obstruction caused by ovarian cancer. (2013454)
1991
48
Carcinoid tumour presenting as recurrent gastric outlet obstruction: a case of long-term survival. (3602991)
1987
49
Preliminary experience with hydrostatic balloon dilation of gastric outlet obstruction. (3710101)
1986
50
Gastric outlet obstruction secondary to a gallstone (Bouveret's syndrome) (4020089)
1985

Variations for Gastric Outlet Obstruction

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Expression for genes affiliated with Gastric Outlet Obstruction

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Expression patterns in normal tissues for genes affiliated with Gastric Outlet Obstruction

Search GEO for disease gene expression data for Gastric Outlet Obstruction.

Pathways for genes affiliated with Gastric Outlet Obstruction

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Pathways related to Gastric Outlet Obstruction according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4GAST, ATP4A
2
Show member pathways
9.3GAST, MLN
3
Show member pathways
9.1ATP12A, ATP4A
4
Show member pathways
calcium transport I37
9.1ATP12A, ATP4A

Compounds for genes affiliated with Gastric Outlet Obstruction

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Compounds related to Gastric Outlet Obstruction according to GeneCards/GeneDecks:

(show all 26)
idCompoundScoreTop Affiliating Genes
1esomeprazole44 50 1111.8GAST, ATP4A
2rabeprazole44 50 24 1112.8GAST, ATP4A
3lansoprazole44 50 24 1112.8GAST, ATP4A
4trimebutine449.7MLN, GAST
5lafutidine449.7GAST, MLN
6bethanechol44 28 1111.7MLN, GAST
7domperidone44 28 1111.7GAST, MLN
8oxyntomodulin44 6110.6MLN, GAST
9ondansetron50 44 24 1112.6GAST, MLN
10ranitidine44 28 24 1112.6GAST, MLN
11famotidine44 2 24 1112.6GAST, MLN
12erythromycin44 2 50 1112.6GAST, MLN
13octreotide44 61 28 1112.6GAST, MLN
14atropine44 28 1111.6MLN, GAST
15acetaminophen44 2 50 24 1113.5GAST, MLN
16nifedipine44 28 50 1112.5GAST, MLN
175-hydroxytryptamine449.5MLN, GAST
18thyroxine44 2410.4GAST, MLN
19acth449.4GAST, MLN
20histamine44 28 2411.3MLN, GAST
21acetylcholine44 50 28 24 1113.2GAST, MLN
22omeprazole44 50 28 24 1113.2GAST, ATP4A, MLN
23potassium44 24 1111.1ATP12A, ATP4A
24pantoprazole44 50 24 1112.0GAST, ATP12A, ATP4A
25Phosphate248.8ATP12A, ATP4A
26hydrogen44 249.8MLN, ATP12A, GAST

GO Terms for genes affiliated with Gastric Outlet Obstruction

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Biological processes related to Gastric Outlet Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1G-protein coupled receptor signaling pathwayGO:0071869.3GAST, MLN
2ATP biosynthetic processGO:0067549.0ATP12A, ATP4A
3ion transmembrane transportGO:0342208.8ATP12A, ATP4A

Molecular functions related to Gastric Outlet Obstruction according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1hormone activityGO:0051799.3GAST, MLN
2hydrogen:potassium-exchanging ATPase activityGO:0089008.8ATP12A, ATP4A

Products for genes affiliated with Gastric Outlet Obstruction

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  • Antibodies
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Sources for Gastric Outlet Obstruction

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet