MCID: GST023
MIFTS: 54

Gastric Ulcer

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastric Ulcer

MalaCards integrated aliases for Gastric Ulcer:

Name: Gastric Ulcer 12 52 14 69
Acute Gastric Ulcer Without Mention of Hemorrhage or Perforation, Without Mention of Obstruction 12
Chronic Gastric Ulcer Without Hemorrhage and Without Perforation but with Obstruction 12
Chronic Gastric Ulcer Without Mention of Hemorrhage or Perforation, with Obstruction 12
Acute Gastric Ulcer with Hemorrhage and Perforation, Without Mention of Obstruction 12
Acute Gastric Ulcer Without Hemorrhage, Without Perforation and Without Obstruction 12
Acute Gastric Ulcer with Hemorrhage and with Perforation but Without Obstruction 12
Acute Gastric Ulcer with Hemorrhage, with Perforation and with Obstruction 12
Acute Gastric Ulcer with Hemorrhage and Perforation, with Obstruction 12
Chronic Gastric Ulcer Without Hemorrhage and Without Perforation 12
Acute Gastric Ulcer Without Hemorrhage and Without Perforation 12
Acute Gastric Ulcer with Hemorrhage and Perforation [dup] 12
Acute Gastric Ulcer with Perforation, with Obstruction 12
Acute Gastric Ulcer with Hemorrhage, with Obstruction 12
Acute Gastric Ulcer with Haemorrhage and Perforation 12
Acute Gastric Ulcer with Perforation and Obstruction 12
Acute Gastric Ulcer with Hemorrhage and Obstruction 12
Acute Gastric Ulcer with Hemorrhage and Perforation 12
Acute Gastric Ulcer with Perforation 12
Bleeding Acute Gastric Ulcer 12
Stomach Ulcer 42

Classifications:



Summaries for Gastric Ulcer

MalaCards based summary : Gastric Ulcer, also known as acute gastric ulcer without mention of hemorrhage or perforation, without mention of obstruction, is related to acute pancreatitis and choroiditis. An important gene associated with Gastric Ulcer is HRH2 (Histamine Receptor H2), and among its related pathways/superpathways are PEDF Induced Signaling and Akt Signaling. The drugs Amoxicillin and Clarithromycin have been mentioned in the context of this disorder. Affiliated tissues include testes, liver and endothelial, and related phenotypes are digestive/alimentary and neoplasm

Related Diseases for Gastric Ulcer

Diseases related to Gastric Ulcer via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 232)
id Related Disease Score Top Affiliating Genes
1 acute pancreatitis 29.8 CXCL8 IL1B PTGS2
2 choroiditis 29.4 CXCL8 IL1B TNF
3 eosinophilic gastroenteritis 28.8 CXCL8 GAST HRH2 IL1B IL1RN PTGS2
4 peptic ulcer disease 11.0
5 chronic erosive gastritis 11.0
6 neonatal marfan syndrome 10.6 CXCL8 PTGS2
7 gastric cancer risk after h. pylori infection 10.6 IL1B IL1RN
8 oculomotor nerve paralysis 10.6 CXCL8 IL1B
9 common peroneal nerve lesion 10.6 CXCL8 IL1B
10 pediatric infratentorial ependymoblastoma 10.5 GAST HRH2 PTGS2
11 milk allergy 10.5 IL1B IL1RN
12 tabatznik syndrome 10.5 IL1B TNF
13 infancy electroclinical syndrome 10.5 CXCL8 IL1B
14 sternal cleft 10.5 IL1B TNF
15 congenital insensitivity to pain with hyperhidrosis 10.4 CXCL8 IL1RN
16 ovarian remnant syndrome 10.4 PTGS1 PTGS2
17 pulmonary hypertension 10.4 IL1B TNF
18 hidradenitis 10.4 CXCL8 IL1B PTGS2
19 nail disorder, nonsyndromic congenital, 1 10.4 EGF FGF2 PTGS2
20 neuroendocrine tumor 10.4 PTGS1 PTGS2
21 colorectal adenoma 10.4 FGF2 HGF
22 chancroid 10.4 CXCL8 IL1B
23 brain ependymoma 10.3 HRH2 PTGS1 PTGS2
24 villous adenoma 10.3 CXCL8 EGF PTGS2
25 cushing's syndrome 10.3 PTGS2 TFF1
26 esophagus squamous cell carcinoma 10.3 FGF2 HGF PTGS2
27 basidiobolomycosis 10.3 CXCL8 TNF
28 bladder calculus 10.3 IL1RN TNF
29 spirillary rat-bite fever 10.3 CXCL8 TNF
30 cutaneous leishmaniasis 10.3 HGF TNF
31 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 10.3 IL1B TNF
32 iris mixed cell melanoma 10.3 GAST HRH2
33 gastritis 10.2
34 tarsal tunnel syndrome 10.2 CXCL8 TNF
35 halal setton wang syndrome 10.2 CXCL8 TNF
36 walker dyson syndrome 10.2 IL1B IL1RN TNF
37 upper gum cancer 10.2 IL1B TNF
38 indolent myeloma 10.2 IL1B IL1RN TNF
39 benign neonatal seizures 10.2 IL1B IL1RN TNF
40 keloids 10.2 IL1B IL1RN TNF
41 noma 10.2 IL1B IL1RN TNF
42 osmotic diarrhea 10.2 IL1B IL1RN TNF
43 iida kannari syndrome 10.2 IL1B IL1RN TNF
44 amyotrophic lateral sclerosis type 10 10.2 CXCL8 IL1B TNF
45 epulis 10.2 CXCL8 IL1B TNF
46 acquired thrombocytopenia 10.1 CXCL8 IL1B TNF
47 testicular infarct 10.1 CXCL8 IL1B TNF
48 ovarian mucinous adenofibroma 10.1 CXCL8 IL1B TNF
49 duodenitis 10.1
50 neuropathy, hereditary sensory and autonomic, type vi 10.1 CXCL8 FGF2 HGF

Graphical network of the top 20 diseases related to Gastric Ulcer:



Diseases related to Gastric Ulcer

Symptoms & Phenotypes for Gastric Ulcer

MGI Mouse Phenotypes related to Gastric Ulcer:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 digestive/alimentary MP:0005381 9.5 EGF GAST HRH2 PTGS1 PTGS2 TFF1
2 neoplasm MP:0002006 9.17 FGF2 GAST IL1B PTGS1 PTGS2 TFF1

Drugs & Therapeutics for Gastric Ulcer

Drugs for Gastric Ulcer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 216)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Amoxicillin Approved, Vet_approved Phase 4,Phase 2,Phase 3 26787-78-0 33613 2171
2
Clarithromycin Approved Phase 4,Phase 2,Phase 3 81103-11-9 84029
3
Dexlansoprazole Approved Phase 4,Phase 3,Phase 1 138530-94-6, 103577-45-3 9578005
4
Lansoprazole Approved, Investigational Phase 4,Phase 3,Phase 1 103577-45-3 3883
5
Metronidazole Approved Phase 4,Phase 2,Phase 3 443-48-1 4173
6
Rabeprazole Approved, Investigational Phase 4,Phase 2,Phase 3 117976-89-3 5029
7
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-78-2 2244
8
Celecoxib Approved, Investigational Phase 4,Phase 3 169590-42-5 2662
9
Esomeprazole Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 161796-78-7, 119141-88-7 4594 9579578
10
Naproxen Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 22204-53-1 1302 156391
11
Ecabet Approved, Investigational Phase 4 33159-27-2, 86408-72-2 65781
12
Omeprazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 73590-58-6 4594
13
Pantoprazole Approved Phase 4,Phase 3,Phase 2,Phase 1 102625-70-7 4679
14
Ticlopidine Approved Phase 4,Phase 3,Phase 1 55142-85-3 5472
15
Sucralfate Approved Phase 4,Phase 2 54182-58-0
16
Famotidine Approved Phase 4,Phase 3 76824-35-6 3325
17
Histamine Approved, Investigational Phase 4,Phase 3,Phase 1 75614-87-8, 51-45-6 774
18
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
19
Sulpiride Approved Phase 4 15676-16-1 5355
20
Remifentanil Approved Phase 4 132875-61-7 60815
21
Colchicine Approved Phase 4 64-86-8 6167 2833
22
Triamcinolone Approved, Vet_approved Phase 4 124-94-7 31307
23
Ranitidine Approved Phase 4,Phase 3 66357-59-3, 66357-35-5 3001055
24
Coal tar Approved Phase 4 8007-45-2
25
Loxoprofen Approved Phase 4 68767-14-6, 80382-23-6 3965
26
Pectin Approved, Vet_approved Phase 4 9000-69-5 441476
27
Clopidogrel Approved, Nutraceutical Phase 4,Phase 3,Phase 1 120202-66-6, 113665-84-2 60606
28 Rebamipide Investigational Phase 4,Phase 3,Phase 2 90098-04-7
29 Benzimidazole Experimental Phase 4 51-17-2
30 Antacids Phase 4,Phase 2,Phase 3,Phase 1
31 Anti-Bacterial Agents Phase 4,Phase 2,Phase 3
32 Anti-Infective Agents Phase 4,Phase 2,Phase 3,Phase 1
33 Anti-Ulcer Agents Phase 4,Phase 2,Phase 3,Phase 1
34 Cytochrome P-450 CYP3A Inhibitors Phase 4,Phase 2,Phase 3
35 Cytochrome P-450 Enzyme Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
36 Gastrointestinal Agents Phase 4,Phase 2,Phase 3,Phase 1
37
Proton pump inhibitors Phase 4,Phase 2,Phase 3,Phase 1
38 Antiparasitic Agents Phase 4,Phase 2,Phase 3
39 Antiprotozoal Agents Phase 4,Phase 2,Phase 3
40 Analgesics Phase 4,Phase 3,Phase 2,Phase 1
41 Analgesics, Non-Narcotic Phase 4,Phase 3,Phase 2,Phase 1
42 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1
43 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3,Phase 2,Phase 1
44 Antipyretics Phase 4,Phase 3,Phase 2,Phase 1
45 Antirheumatic Agents Phase 4,Phase 3,Phase 2,Phase 1
46 Cyclooxygenase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
47 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Phase 1
48 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
49 Platelet Aggregation Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
50 Cyclooxygenase 2 Inhibitors Phase 4,Phase 3

Interventional clinical trials:

(show top 50) (show all 268)

id Name Status NCT ID Phase Drugs
1 H. Pylori Eradication on Healing of Iatrogenic Gastric Ulcer by Endoscopic Mucosal Resection Unknown status NCT00926809 Phase 4 Lansoprazole (proton pump inhibitor), amoxicillin, clarythromycin;Lansoprazole (proton pump inhibitor), placebo
2 Concomitant Therapy of H. Pylori Unknown status NCT01922765 Phase 4 amoxicillin, clarithromycin, metronidazole, rabeprazole
3 The Safety and Efficacy of Albis®: The Prevention of Aspirin-induced Gastrointestinal Ulcers in Patients Unknown status NCT01397240 Phase 4 Albis Tab;Placebo
4 Gastro-protective Effect and Pain Relief Effect of Naxozol Compared to Celecoxib in Patients With Osteoarthritis Unknown status NCT02355236 Phase 4 Naproxen/Esomeprazol 500/20mg;Celecoxib 200mg;Naxozol-Placebo;Comparator-Placebo
5 Efficacy of Ecabet Sodium and Proton Pump Inhibitor Combination Therapy in the Treatment of Iatrogenic Ulcer After Endoscopic Submucosal Dissection Unknown status NCT01308177 Phase 4 Ecabet
6 Study Comparing Sequential and Concomitant Therapy for Helicobacter Pylori Eradication in Routine Clinical Practice Unknown status NCT01273441 Phase 4 PPI, amoxicillin, metronidazole and clarithromycin;PPI, amoxicillin, metronidazole and clarithromycin
7 14-day Quadruple Hybrid vs. Concomitant Therapies for Helicobacter Pylori Eradication Unknown status NCT01464060 Phase 4 PPI, amoxicillin, metronidazole and clarithromycin;PPI, amoxicillin, metronidazole and clarithromycin
8 Does Early Re-administration of Aspirin/Clopidogrel Increase the Risk of Bleeding From Artificial Ulcer After EMR or ESD? Unknown status NCT01621451 Phase 4 aspirin and/or clopidogrel;aspirin and/or clopidogrel
9 Compare Efficacy of Gastric Acid Suppression by Oral and Intravenous Administration of Esomeprazole in Patients With Peptic Ulcer Unknown status NCT00471029 Phase 4 esomeprazole
10 ZeroTolerance Mucositis: Managing Oral and Alimentary Mucositis With High Potency Sucralfate - ProThelial Unknown status NCT02016807 Phase 4
11 Esomeprazole or Famotidine in the Management of Aspirin Related Non-Ulcer Dyspepsia Unknown status NCT00978159 Phase 4 esomeprazole;Famotidine
12 Gastric Functions & Proton Pump Inhibitor( PPI) Study Unknown status NCT00951431 Phase 4 Esomeprazole;Placebo
13 Healing Effects of Rebamipide and Omeprazole in Helicobacter Pylori-positive Gastric Ulcer After Eradication Therapy Completed NCT00272467 Phase 4 Rebamipide;Omeprazole
14 Post-Marketing Clinical Study of Rebamipide in Patients With Gastric Ulcer Completed NCT00233389 Phase 4 Rebamipide
15 A Double-blind, Comparative Study in Patients With Gastric Ulcer to Evaluate the Efficacy of Combination Use of E0671 and Rabeprazole Sodium Completed NCT00125736 Phase 4 Teprenone
16 Efficacy and Safety of Teprenone in Patients With Acute Gastritis, Acute Gastric Lesion of Chronic Gastritis With Acute Exacerbation or Gastric Ulcer Completed NCT01190657 Phase 4 Selbex;Selbex
17 An Open-label, Exploratory Trial to Assess Gastric Acid Control in Critically Ill Subjects Receiving Nexium Completed NCT00428701 Phase 4 Esomeprazole Sodium
18 Effect of Prevacid on Prostaglandin Levels in Patient With Stress Ulcer Completed NCT00239551 Phase 4 Prevacid
19 Pharmacogenetics of Gastrointestinal Bleeding Completed NCT00190255 Phase 4
20 Opioid-induced Hyperalgesia After Remifentanil Infusion Completed NCT01702389 Phase 4 Remifentanil
21 Importance of Cytokines in Peptic Ulcer Disease: Implications for Treatment Completed NCT00534443 Phase 4
22 Colchicine Or Naproxen Treatment for ACute gouT Completed NCT01994226 Phase 4 Low-dose colchicine;Naproxen 750 mg/250 mg
23 Treatment of Upper Eyelid Retraction Related to Thyroid-associated Ophthalmopathy Using Subconjunctival Triamcinolone Injections Completed NCT01599273 Phase 4 subconjunctival triamcinolone injection
24 Argon Plasma Coagulation for Bleeding Peptic Ulcers Completed NCT02241044 Phase 4
25 Ulcer Prevention Study in Post Gastric Bypass Patients Completed NCT00557349 Phase 4 Omeprazole;Famotidine
26 Gastric pH in Critically Ill Patients Completed NCT00590928 Phase 4 esomeprazole;ranitidine
27 Effects of 2 Different Doses of Pantoprazole on Gastric pH and Recurrent Bleeding in Patients Who Bled From Peptic Ulcers Completed NCT00279123 Phase 4 pantoprazole infusion;pantoprazole bolus;no treatment
28 The Effects of Aspirin and Acetaminophen on the Stomach in Healthy Volunteers Completed NCT00594867 Phase 4 Acetaminophen - 4 grams per day + Placebo;Aspirin - 325 mg per day + Placebo;Acetaminophen 4 gram per day + Aspirin 325 mg per day
29 Use Of Esomeprazole In Postoperative Bariatric Surgery Patients Users And Non-Users Of Nonsteroidal Anti-Inflammatory Drugs (NSAIDS) Completed NCT00608712 Phase 4 Esomeprazole
30 Comparison of Esomeprazole and Famotidine for Stress Ulcer Prophylaxis in Neurosurgical Intensive Care Unit Completed NCT00633035 Phase 4 esomeprazole 40 mg;famotidine 20 mg
31 Effect of Naproxen, Aspirin, Celecoxib, or Clopidogrel on the Healing of Stomach and Intestinal Ulcers Completed NCT00778193 Phase 4 Naproxen;Aspirin;Celecoxib;Clopidogrel;Placebo
32 Effects of Oral Rabeprazole on the Prevention of Ulcer Bleeding Following Endoscopic Mucosal Resection Completed NCT00844675 Phase 4 rabeprazole;placebo
33 A Clinico-Bacteriological Study and Effect of Stress Ulcer Prophylaxis on Occurrence of Ventilator Associated Pneumonia Completed NCT00702871 Phase 4 Ranitidine;Sucralfate
34 Different Dose of Intravenous Omeprazole to Treat Bleeding Ulcer With Adherent Clot Completed NCT02536989 Phase 4 omeprazole;omeprazole
35 Treatment of Zollinger-Ellison Syndrome With Prevacid Completed NCT00204373 Phase 4 Lansoprazole (Prevacid)
36 Fast-track Surgery for Perforated Peptic Ulcers Completed NCT01620671 Phase 4
37 Comparison of Sequential or Concomitant Therapy for Helicobacter Pylori Infection Completed NCT00656968 Phase 4 10-day sequential treatment;10-day concomitant therapy
38 A Study of the Safety of Rabeprazole Administered to Adults With Gastroesophageal Reflux Disease (GERD) Completed NCT00216489 Phase 4 rabeprazole sodium
39 A Study of Rabeprazole and Pantoprazole on Stomach Acid and Esophageal Acid Exposure in Patients With Gastroesophageal Reflux Disease (GERD) and a History of Nighttime Heartburn Completed NCT00237367 Phase 4 rabeprazole and pantoprazole
40 Study Of Celecoxib In Healthy Subjects Completed NCT00994461 Phase 4 Celecoxib;Loxoprofen;Placebo
41 Effect of ALBIS on Gastroduodenal Mucosal Injury in Patients Receiving Dual Antiplatelet Therapy After Percutaneous Coronary Intervention Recruiting NCT02175186 Phase 4 ALBIS;Placebo
42 Helicobacter Eradication Aspirin Trial Recruiting NCT01506986 Phase 4 Lansoprazole 30mg, Clarithromycin 500mg, Metronidazole 400mg;Placebo lansoprazole 30mg, clarithromycin 500mg, metronidazole 400mg
43 Effects of Ilaprazole on Ulcer Healing Rate and Prevention of Gastrointestinal Bleeding in the Patients Undergone ESD. Recruiting NCT02638584 Phase 4 Ilaprazole;Rabeprazole
44 Intraluminal Therapy for Helicobacter Pylori Infection Recruiting NCT03124420 Phase 4 Lansoprazole;Amoxicillin;Clarithromycin
45 Proton Pump Inhibitor Prevent Dual Antiplatelet Agents Induced Gastrointestinal Ulcer After Coronary Artery Bypass Graft Not yet recruiting NCT03038009 Phase 4 Pantoprazole
46 The Influence of Helicobacter Pylori Eradication on Gastric Pathology: a Long-term, Prospective Cohort Study Not yet recruiting NCT02933229 Phase 4 H. pylori eradication
47 Mono- Versus Dual antiPlatelet Therapy During 6-12 Months After New Generation Drug Eluting Stent Implantation Not yet recruiting NCT03198741 Phase 4 Aspirin + clopidogrel;Clopidogrel monotherapy;Aspirin monotherapy
48 Prevention of Upper Gastrointestinal Hemorrhage Using Albis® in the Patients of Locally Advanced Pancreatic Cancer Who Underwent Concurrent Chemoradiotherapy Not yet recruiting NCT02570529 Phase 4 Albis®;Placebo
49 Comparison of Intravenous Pantoprazole and Famotidine for Stress Ulcer Prophylaxis Terminated NCT00839488 Phase 4 pantoprazole 40 mg iv;famotidine 20 mg iv
50 Lansoprazole Preventing Gastroduodenal Stress Ulcerations Terminated NCT00220909 Phase 4 Lansoprazole

Search NIH Clinical Center for Gastric Ulcer

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: stomach ulcer

Genetic Tests for Gastric Ulcer

Anatomical Context for Gastric Ulcer

MalaCards organs/tissues related to Gastric Ulcer:

39
Testes, Liver, Endothelial, Colon, Thyroid, Pancreas, Heart

Publications for Gastric Ulcer

Articles related to Gastric Ulcer:

(show top 50) (show all 789)
id Title Authors Year
1
Gastroprotective and Antiulcer Effects of Celastrus paniculatus Seed Oil Against Several Gastric Ulcer Models in Rats. ( 28816560 )
2017
2
Recurrent gastric ulcer and cholangitis caused by ectopic drainage of the bile duct into the stomach. ( 28868226 )
2017
3
Enhancement of Gastric Ulcer Healing and Angiogenesis by Hepatocyte Growth Factor Gene Mediated by Attenuated Salmonella in Rats. ( 28049228 )
2017
4
Cytomegalovirus Gastric Ulcer Complicated with Pyloric Obstruction in a Patient with Ulcerative Colitis. ( 28637105 )
2017
5
Comparison of the therapeutic effects of sildenafil citrate, heparin and neuropeptides in a rat model of acetic acid-induced gastric ulcer. ( 28807720 )
2017
6
Protective effects of bilobalide against ethanol-induced gastric ulcer in vivo/vitro. ( 27903426 )
2017
7
Perforated gastric ulcer in severe dengue infection: A case report. ( 28889137 )
2017
8
A Rare Case of Gastric Ulcer Penetrating the Pancreas that was Successfully Managed by Conservative Therapy. ( 28794357 )
2017
9
Modulatory effect of silymarin on nuclear factor-erythroid-2-related factor 2 regulated redox status, nuclear factor-I_B mediated inflammation and apoptosis in experimental gastric ulcer. ( 28648817 )
2017
10
Tracheoesophageal fistula after total resection of gastric conduit for gastro-aortic fistula due to gastric ulcer. ( 28831760 )
2017
11
Analyzing the influence of gastric intestinal metaplasia on gastric ulcer healing in Helicobacter pylori-infected patients without atrophic gastritis. ( 28049442 )
2017
12
Protective Effect of Two Extracts of Cydonia oblonga Miller (Quince) Fruits on Gastric Ulcer Induced by Indomethacin in Rats. ( 28900537 )
2017
13
Surgical Scales: Primary Closure versus Gastric Resection for Perforated Gastric Ulcer - A Surgical Debate. ( 28584503 )
2017
14
Metastatic Renal Cell Carcinoma Presenting as Gastric Ulcer: Case Report and Literature Review. ( 28713604 )
2017
15
Effects of quinine on gastric ulcer healing in Wistar rats. ( 28665790 )
2017
16
Protective effect of oleane-12-en-3I^-ol-28-oic acid 3I^-D-glucopyranoside in ethanol induced gastric ulcer by enhancing the prostaglandin E2 level. ( 28942137 )
2017
17
Management of Percutaneous Endoscopic Gastrostomy Site Gastric Ulcer in a Patient with an Esophageal Stricture and Hiatus Hernia. ( 28835092 )
2017
18
Comparison of aloe vera and omeprazole in the treatment of equine gastric ulcer syndrome. ( 28555939 )
2017
19
Cigarette Lighter Fluid Induced Gastric Ulcer: A Severe Complication of Delayed Foreign Body Removal. ( 28894611 )
2017
20
Gastric Ulcer Complications after the Introduction of Proton Pump Inhibitors into Clinical Routine: 20-Year Experience. ( 28785572 )
2017
21
Protective effect of salusin-I+ and salusin-I^ against ethanol-induced gastric ulcer in rats. ( 28917082 )
2017
22
Mechanistic evaluation of gastroprotective effects of Kangfuxin on ethanol-induced gastric ulcer in mice. ( 28606470 )
2017
23
Involvement of MAPK/NF-I_B signal transduction pathways: Camellia japonica mitigates inflammation and gastric ulcer. ( 28926923 )
2017
24
Gastric ulcer penetrating the liver. ( 26987967 )
2016
25
Successful treatment of a primary gastric plasmacytoma mimicking intractable gastric ulcer by using high-dose dexamethasone therapy: a case report. ( 27036197 )
2016
26
Antiulcer mechanisms of Vernonia condensata Baker: A medicinal plant used in the treatment of gastritis and gastric ulcer. ( 26956376 )
2016
27
Gastritis and Gastric Ulcers in Working Dogs. ( 27092307 )
2016
28
Protective effect of hydro-alcoholic extract of Ruta graveolens Linn. leaves on indomethacin and pylorus ligation-induced gastric ulcer in rats. ( 27297508 )
2016
29
Drug-disease interactions: narrative review of aspirin in gastric ulcer. ( 27322160 )
2016
30
Anti-ulcerogenic effect of cavidine against ethanol-induced acute gastric ulcer in mice and possible underlying mechanism. ( 27380619 )
2016
31
Protective Effect of Cod (Gadus macrocephalus) Skin Collagen Peptides on Acetic Acid-Induced Gastric Ulcer in Rats. ( 27219644 )
2016
32
Acute thrombosis of a transplanted renal artery after gastric ulcer bleeding in a patient with a long-term well-functioning renal allograft: A case report and literature review. ( 27472705 )
2016
33
A rare presentation of gastric mucormycosis presenting as perforated gastric ulcer in pregnancy. ( 27728458 )
2016
34
Therapeutic effect of low molecular weight chitosan containing sepia ink on ethanol-induced gastric ulcer in rats. ( 28076505 )
2016
35
Splenic artery pseudoaneurysm causing brisk upper-GIA bleedA fromA gastric ulcer. ( 26802194 )
2016
36
Gastric ulcer that turned out to be metastasis of a synovial sarcoma: A case report and literature review. ( 28087966 )
2016
37
Re: Double pylorus from a chronic gastric ulcer: an interesting and rare case. ( 27109304 )
2016
38
Evaluation of protective effects of costunolide and dehydrocostuslactone on ethanol-induced gastric ulcer in mice based on multi-pathway regulation. ( 26970604 )
2016
39
A bleeding gastric ulcer caused by anisakiasis. ( 27366042 )
2016
40
Misplaced "bear claw" in a bleeding gastric ulcer: What next? ( 26979161 )
2016
41
Erratum: Utilisation of the falciform ligament pedicle flap as an alternative approach for the repair of a perforated gastric ulcer. ( 27664223 )
2016
42
Interaction of lafutidine in binding to human serum albumin in gastric ulcer therapy: STD-NMR, WaterLOGSY-NMR, NMR relaxation times, Tr-NOESY, molecule docking, and spectroscopic studies. ( 27457418 )
2016
43
Gastroprotective Effect of Combination of Hot Water Extracts of Licorice (Glycyrrhiza glabra), Pulasari Stem Bark (Alyxia reinwardtii), and Sembung Leaf (Blumea balsamifera) Against Aspirin-Induced Gastric Ulcer Model Rats. ( 26976086 )
2016
44
Utilisation of the falciform ligament pedicle flap as an alternative approach for the repair of a perforated gastric ulcer. ( 27102415 )
2016
45
Management of Giant Gastric Ulcer Perforation: Report of a Case and Review of the Literature. ( 28050305 )
2016
46
Dietary composition influences incidence of Helicobacter pylori-induced iron deficiency anemia and gastric ulceration. ( 27620719 )
2016
47
A case of left subphrenic abscess caused by gastric ulcer penetration that was successfully treated with endoscopic transgastric drainage. ( 27916771 )
2016
48
Epstein-Barr virus gastric ulcer associated with ruxolitinib. ( 27411541 )
2016
49
Gastric Anisakiasis with a Gastric Ulcer. ( 27980274 )
2016
50
Therapeutic and recurrence-preventing effects of Qi-Replenishing and Blood-Activating Formula in rats with acetic acid-induced gastric ulcer. ( 26851793 )
2016

Variations for Gastric Ulcer

Expression for Gastric Ulcer

Search GEO for disease gene expression data for Gastric Ulcer.

Pathways for Gastric Ulcer

Pathways related to Gastric Ulcer according to GeneCards Suite gene sharing:

(show all 44)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.54 CXCL8 EGF HGF IL1B PTGS1 PTGS2
2
Show member pathways
13.3 CXCL8 EGF FGF2 HGF IL1B TNF
3
Show member pathways
13.16 CXCL8 EGF FGF2 HGF IL1B TNF
4
Show member pathways
13.12 CXCL8 EGF FGF2 HGF IL1B IL1RN
5
Show member pathways
12.87 CXCL8 IL1B IL1RN PTGS2 TNF
6 12.61 EGF FGF2 IL1B TNF
7 12.56 EGF FGF2 HGF PTGS2 TNF
8
Show member pathways
12.55 EGF FGF2 HGF IL1B TNF
9 12.49 CXCL8 EGF FGF2 HGF PTGS2
10 12.37 IL1B IL1RN PTGS1 PTGS2 TNF
11
Show member pathways
12.22 CXCL8 IL1B PTGS2 TNF
12
Show member pathways
12.21 EGF HRH2 PTGS2 TFF1
13
Show member pathways
12.12 CXCL8 IL1B PTGS2 TNF
14
Show member pathways
12.05 CXCL8 IL1B TNF
15 12.02 CXCL8 IL1B IL1RN TNF
16 11.98 EGF FGF2 HGF
17 11.97 CXCL8 EGF TNF
18
Show member pathways
11.9 CYP2C19 PTGS1 PTGS2
19 11.88 CYP2C19 PTGS1 PTGS2
20 11.86 IL1B PTGS2 TNF
21 11.84 CXCL8 IL1B PTGS2 TNF
22 11.81 CXCL8 IL1B TNF
23 11.79 CXCL8 IL1B TNF
24 11.75 CXCL8 IL1B TNF
25 11.73 FGF2 HGF PTGS2
26 11.71 CXCL8 IL1B PTGS2 TNF
27
Show member pathways
11.66 CXCL8 PTGS2 TNF
28 11.66 CXCL8 IL1B TNF
29 11.49 CXCL8 IL1B TNF
30 11.49 CXCL8 FGF2 HGF IL1B PTGS2 TNF
31
Show member pathways
11.47 CXCL8 IL1B PTGS2 TNF
32 11.4 EGF FGF2 HGF
33 11.31 CXCL8 HGF IL1B TNF
34 11.24 CXCL8 IL1B IL1RN PTGS2 TNF
35 11.09 CXCL8 HGF IL1B TNF
36 11.07 CXCL8 TNF
37 11.07 PTGS1 PTGS2
38 11.05 PTGS1 PTGS2
39 11.03 IL1B TNF
40 10.9 CXCL8 EGF FGF2 HGF IL1B TNF
41 10.87 IL1B TNF
42 10.84 CXCL8 PTGS1 PTGS2 TNF
43 10.83 PTGS1 PTGS2
44 10.27 GAST HRH2

GO Terms for Gastric Ulcer

Cellular components related to Gastric Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.61 CXCL8 EGF FGF2 GAST HGF IL1B
2 organelle membrane GO:0031090 9.33 CYP2C19 PTGS1 PTGS2
3 extracellular space GO:0005615 9.28 CXCL8 EGF FGF2 GAST HGF IL1B

Biological processes related to Gastric Ulcer according to GeneCards Suite gene sharing:

(show all 29)
id Name GO ID Score Top Affiliating Genes
1 negative regulation of cell proliferation GO:0008285 9.94 CXCL8 IL1B PTGS2 TFF1
2 immune response GO:0006955 9.89 CXCL8 HRH2 IL1B IL1RN TNF
3 positive regulation of cell proliferation GO:0008284 9.84 EGF FGF2 HGF PTGS2
4 angiogenesis GO:0001525 9.83 CXCL8 EGF FGF2 PTGS2
5 phosphatidylinositol-mediated signaling GO:0048015 9.79 EGF FGF2 HGF
6 phosphatidylinositol phosphorylation GO:0046854 9.77 EGF FGF2 HGF
7 regulation of phosphatidylinositol 3-kinase signaling GO:0014066 9.74 EGF FGF2 HGF
8 response to glucocorticoid GO:0051384 9.73 IL1RN PTGS2 TNF
9 MAPK cascade GO:0000165 9.72 EGF FGF2 HGF IL1B TNF
10 positive regulation of MAP kinase activity GO:0043406 9.69 EGF FGF2 TNF
11 positive regulation of angiogenesis GO:0045766 9.67 CXCL8 FGF2 HGF IL1B
12 prostaglandin metabolic process GO:0006693 9.64 PTGS1 PTGS2
13 embryonic digestive tract development GO:0048566 9.63 CXCL8 TNF
14 negative regulation of lipid catabolic process GO:0050995 9.63 IL1B TNF
15 inflammatory response GO:0006954 9.63 CXCL8 IL1B IL1RN PTGS1 PTGS2 TNF
16 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.62 IL1B TNF
17 prostaglandin biosynthetic process GO:0001516 9.62 PTGS1 PTGS2
18 regulation of I-kappaB kinase/NF-kappaB signaling GO:0043122 9.61 IL1B TNF
19 positive regulation of nitric oxide biosynthetic process GO:0045429 9.61 IL1B PTGS2 TNF
20 positive regulation of heterotypic cell-cell adhesion GO:0034116 9.59 IL1B TNF
21 cyclooxygenase pathway GO:0019371 9.58 PTGS1 PTGS2
22 positive regulation of chemokine biosynthetic process GO:0045080 9.58 IL1B TNF
23 regulation of establishment of endothelial barrier GO:1903140 9.55 IL1B TNF
24 sequestering of triglyceride GO:0030730 9.46 IL1B TNF
25 positive regulation of NF-kappaB import into nucleus GO:0042346 9.43 IL1B PTGS2 TNF
26 positive regulation of calcidiol 1-monooxygenase activity GO:0060559 9.4 IL1B TNF
27 activation of MAPK activity GO:0000187 9.35 EGF FGF2 HGF IL1B TNF
28 fever generation GO:0001660 9.18 IL1B
29 positive regulation of fever generation GO:0031622 8.8 IL1B PTGS2 TNF

Molecular functions related to Gastric Ulcer according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 heme binding GO:0020037 9.58 CYP2C19 PTGS1 PTGS2
2 Ras guanyl-nucleotide exchange factor activity GO:0005088 9.5 EGF FGF2 HGF
3 growth factor activity GO:0008083 9.46 EGF FGF2 HGF TFF1
4 phosphatidylinositol-4,5-bisphosphate 3-kinase activity GO:0046934 9.43 EGF FGF2 HGF
5 interleukin-1 receptor binding GO:0005149 9.37 IL1B IL1RN
6 cytokine activity GO:0005125 9.02 CXCL8 FGF2 IL1B IL1RN TNF
7 prostaglandin-endoperoxide synthase activity GO:0004666 8.96 PTGS1 PTGS2

Sources for Gastric Ulcer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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