MCID: GST090
MIFTS: 21

Gastroduodenal Crohn's Disease

Categories: Gastrointestinal diseases

Aliases & Classifications for Gastroduodenal Crohn's Disease

MalaCards integrated aliases for Gastroduodenal Crohn's Disease:

Name: Gastroduodenal Crohn's Disease 12 14
Upper Gi Crohn's Disease 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060191
ICD10 33 K50.0

Summaries for Gastroduodenal Crohn's Disease

Disease Ontology : 12 An inflammatory bowel disease characterized by inflammation located in stomach and located in duodenum, has symptom nausea, has symptom vomiting, has symptom weight loss and has symptom loss of appetite.

MalaCards based summary : Gastroduodenal Crohn's Disease, also known as upper gi crohn's disease, is related to scrotum melanoma and congenital aphakia. An important gene associated with Gastroduodenal Crohn's Disease is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2). Affiliated tissues include small intestine, and related phenotype is homeostasis/metabolism.

Related Diseases for Gastroduodenal Crohn's Disease

Diseases related to Gastroduodenal Crohn's Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 42)
id Related Disease Score Top Affiliating Genes
1 scrotum melanoma 10.2 ATP12A ATP4A
2 congenital aphakia 10.2 ATP12A ATP4A
3 shwartzman phenomenon 10.2 ATP12A ATP4A
4 primary syphilis 10.2 ATP12A ATP4A
5 bone giant cell sarcoma 10.2 ATP12A ATP4A
6 urethral calculus 10.2 ATP12A ATP4A
7 breast ductal adenoma 10.2 ATP12A ATP4A
8 hypopituitarism 10.2 ATP12A ATP4A
9 abnormal pupillary function 10.2 ATP12A ATP4A
10 atheroembolism of kidney 10.2 ATP12A ATP4A
11 microphthalmia, syndromic 12 10.2 ATP12A ATP4A
12 synostosis 10.2 ATP12A ATP4A
13 adult xanthogranuloma 10.2 ATP12A ATP4A
14 polysyndactyly with cardiac malformation 10.2 ATP12A ATP4A
15 focal hand dystonia 10.2 ATP12A ATP4A
16 cloacal exstrophy 10.2 ATP12A ATP4A
17 thrombocytopenia due to platelet alloimmunization 10.2 ATP12A ATP4A
18 proliferative fasciitis 10.2 ATP12A ATP4A
19 hodgkin's paragranuloma 10.1 ATP12A ATP4A
20 bladder neck cancer 10.1 ATP12A ATP4A
21 spinocerebellar ataxia 18 10.1 ATP12A ATP4A
22 intracranial sinus thrombosis 10.1 ATP12A ATP4A
23 fungal gastritis 10.1 ATP12A ATP4A
24 cubitus valgus with mental retardation and unusual facies 10.1 ATP12A ATP4A
25 villous adenocarcinoma 10.1 ATP12A ATP4A
26 ileocolitis 10.1 ATP12A ATP4A
27 mesenteric vascular occlusion 10.0 ATP12A ATP4A
28 scleral staphyloma 10.0 ATP12A ATP4A
29 anterior cerebral artery infarction 10.0 ATP12A ATP4A
30 pediatric infratentorial ependymoblastoma 10.0 ATP12A ATP4A
31 hepatic veno-occlusive disease 9.9 ATP12A ATP4A
32 frontal sinus schneiderian papilloma 9.9 ATP12A ATP4A
33 chemical colitis 9.8 ATP4A TGM2
34 prostatic cyst 9.8 ATP12A ATP4A
35 farber lipogranulomatosis 9.8 ATP12A ATP4A
36 tuberculum sellae meningioma 9.8 ATP12A ATP4A NOD2
37 gnathomiasis 9.7 ATP12A ATP4A
38 muscle cancer 9.6 ATP12A ATP4A GIF
39 allergic urticaria 9.6 ATP12A ATP4A GIF
40 fibrosarcomatous osteosarcoma 9.6 ATP12A ATP4A GIF
41 lymphoma, malt, somatic 9.5 ATP12A ATP4A
42 amyotrophic lateral sclerosis type 5 8.3 ATP12A ATP4A GIF NOD2 TGM2

Graphical network of the top 20 diseases related to Gastroduodenal Crohn's Disease:



Diseases related to Gastroduodenal Crohn's Disease

Symptoms & Phenotypes for Gastroduodenal Crohn's Disease

MGI Mouse Phenotypes related to Gastroduodenal Crohn's Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 8.92 ATP12A ATP4A NOD2 TGM2

Drugs & Therapeutics for Gastroduodenal Crohn's Disease

Search Clinical Trials , NIH Clinical Center for Gastroduodenal Crohn's Disease

Genetic Tests for Gastroduodenal Crohn's Disease

Anatomical Context for Gastroduodenal Crohn's Disease

MalaCards organs/tissues related to Gastroduodenal Crohn's Disease:

39
Small Intestine

Publications for Gastroduodenal Crohn's Disease

Articles related to Gastroduodenal Crohn's Disease:

(show all 20)
id Title Authors Year
1
Isolated gastroduodenal Crohn's disease in a septuagenarian man. ( 24756277 )
2014
2
Gastroduodenal Crohn's disease and pancreatitis. ( 21960927 )
2008
3
Infliximab treatment of massive upper gastrointestinal bleeding in gastroduodenal Crohn's disease. ( 19115158 )
2008
4
Isolated gastroduodenal Crohn's disease presenting with acute pancreatitis. ( 21960926 )
2008
5
Treatment of gastroduodenal Crohn's disease. ( 15711048 )
2005
6
Gastroduodenal Crohn's disease is associated with NOD2/CARD15 gene polymorphisms, particularly L1007P homozygosity. ( 16416181 )
2005
7
Gastroduodenal Crohn's disease. ( 15605018 )
2004
8
Gastroduodenal Crohn's disease. ( 16278730 )
2003
9
Severe gastroduodenal Crohn's disease: surgical treatment. ( 12769448 )
2003
10
Gastroduodenal Crohn's disease: medical management. ( 12769447 )
2003
11
Long-term outcome of endoscopic balloon dilation in obstructive gastroduodenal Crohn's disease. ( 9360875 )
1997
12
Gastroduodenal Crohn's disease: the focus is on focality. ( 9041268 )
1997
13
Repeated hydrostatic balloon dilation in obstructive gastroduodenal Crohn's disease. ( 1916177 )
1991
14
Gastroduodenal Crohn's disease in childhood. ( 2809935 )
1989
15
The diagnosis of gastroduodenal Crohn's disease by endoscopic biopsy. ( 2617164 )
1989
16
Clinical features of gastroduodenal Crohn's disease in adolescents. ( 2709248 )
1989
17
The surgical treatment of gastroduodenal Crohn's disease. ( 4073768 )
1985
18
Gastric retention of enteric-coated sulfasalazine tablets. A complication of gastroduodenal Crohn's disease. ( 6149106 )
1984
19
Gastroduodenal Crohn's disease. ( 6726063 )
1984
20
Gastroduodenal Crohn's disease. Differential diagnosis and treatment. ( 6647159 )
1983

Variations for Gastroduodenal Crohn's Disease

Expression for Gastroduodenal Crohn's Disease

Search GEO for disease gene expression data for Gastroduodenal Crohn's Disease.

Pathways for Gastroduodenal Crohn's Disease

GO Terms for Gastroduodenal Crohn's Disease

Biological processes related to Gastroduodenal Crohn's Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 positive regulation of I-kappaB kinase/NF-kappaB signaling GO:0043123 9.37 NOD2 TGM2
2 ion transport GO:0006811 9.33 ATP12A ATP4A GIF
3 potassium ion transport GO:0006813 9.32 ATP12A ATP4A
4 sodium ion transport GO:0006814 9.26 ATP12A ATP4A
5 proton transport GO:0015992 8.96 ATP12A ATP4A
6 establishment or maintenance of transmembrane electrochemical gradient GO:0010248 8.62 ATP12A ATP4A

Molecular functions related to Gastroduodenal Crohn's Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 sodium:potassium-exchanging ATPase activity GO:0005391 8.96 ATP12A ATP4A
2 hydrogen:potassium-exchanging ATPase activity GO:0008900 8.62 ATP12A ATP4A

Sources for Gastroduodenal Crohn's Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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