MCID: GST045
MIFTS: 46

Gastroenteritis malady

Summaries for Gastroenteritis

Sources:
8Disease Ontology, 34MedlinePlus, 64Wikipedia, 33MalaCards
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MedlinePlus:34 Have you ever had the "stomach flu?" what you probably had was gastroenteritis - not a type of flu at all. gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria or parasites. viral gastroenteritis is the second most common illness in the u.s. the cause is often a norovirus infection. it spreads through contaminated food or water, and contact with an infected person. the best prevention is frequent hand washing. symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever and chills. most people recover with no treatment. the most common problem with gastroenteritis is dehydration. this happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. dehydration is most common in babies, young children, the elderly and people with weak immune systems. nih: national institute of diabetes and digestive and kidney diseases

MalaCards: Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and arthritis. An important gene associated with Gastroenteritis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are Allograft rejection and IL4-mediated signaling events. The drug erythromycin pwdr and the compounds histamine and prednisolone have been mentioned in the context of this disorder.

Disease Ontology:8 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. chemicals and drugs also cause gastroenteritis. the symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia:64 Gastroenteritis or infectious diarrhea is a medical condition characterized by inflammation (\"-itis\")... more...

Aliases & Classifications for Gastroenteritis

Sources:
8Disease Ontology, 10DISEASES, 45Novoseek, 34MedlinePlus, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt
See all sources

Aliases & Descriptions:

gastroenteritis 8 10 45 34 61
cholera morbus 8 61
infectious colitis, enteritis and gastroenteritis 8


External Ids:

Disease Ontology8 DOID:2326
MeSH35 D005759
NCIt40 C34632

Related Diseases for Gastroenteritis

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 208)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilic gastroenteritis31.6CCL11, CSN1S1, IGHE, IL5
2arthritis30.4ALB, LACTB, SRF, ANPEP, CSN1S1
3hypereosinophilic syndrome30.3CCL11, PRG2, IGHE, RNASE3, IL5
4eosinophilic esophagitis30.3CCL11, IL5
5asthma30.3CCL11, CSN1S1, PRG2, IGHE, RNASE3, IL5
6bronchitis30.0LACTB, IL5, RNASE3, IGHE, CCL11
7churg-strauss syndrome30.0IL5, RNASE3
8gastric ulcer30.0HGF, SRF
9urticaria29.7CSN1S1, PRG2, IGHE, RNASE3
10allergic asthma29.7CCL11, IGHE, RNASE3, IL5
11atherosclerosis29.7ALB, SRF, ANPEP, CCL11
12cholera29.7CCL11, CSN1S1
13celiac disease29.7CSN1S1
14angioedema29.7IGHE, RNASE3, IL5
15ulcerative colitis29.7SRF, RNASE3, CSN1S1, CCL11
16eosinophilic enteropathy10.4
17protein-losing enteropathy10.3
18irritable bowel syndrome10.3
19reactive arthritis10.2
20cryptosporidiosis10.2
21listeriosis10.1
22n syndrome10.1
23acute pancreatitis10.1
24acute diarrhea10.1
25intussusception10.1
26guillain-barr� syndrome10.1
27bacteremia10.1
28duodenal ulcer10.0
29toxic megacolon10.0
30obstructive jaundice10.0
31systemic lupus erythematosus10.0
32polyarteritis nodosa10.0
33dyspepsia10.0
34lactose intolerance10.0
35hypertrophic pyloric stenosis10.0
36clostridium difficile10.0
37eosinophilic cystitis10.0
38febrile seizures10.0
39syncope10.0
40ileus10.0
41gastric outlet obstruction10.0
42benign infantile seizures associated to mild gastroenteritis10.0
43food allergy10.0CCL11, CSN3, CSN1S1, IGHE, RNASE3, IL5
44atopic dermatitis10.0CCL11, CSN3, CSN1S1, PRG2, IGHE, RNASE3
45eosinophilia10.0SRF, IL5, RNASE3, IGHE, PRG2, CCL11
46dermatitis10.0IL5, BTD, IGHE, CCL11
47pulmonary eosinophilia10.0CCL11, PRG2, IGHE, RNASE3, IL5
48bullous pemphigoid10.0CCL11, PRG2, IGHE, RNASE3, IL5
49allergic conjunctivitis10.0IL5, RNASE3, IGHE, CCL11
50kimura disease10.0IL5, RNASE3, IGHE, PRG2

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to gastroenteritis

Clinical Features for Gastroenteritis

Drugs & Therapeutics for Gastroenteritis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
See all sources

Approved drugs:

Search CenterWatch for Gastroenteritis

Drug clinical trials:

Search ClinicalTrials for Gastroenteritis

Search NIH Clinical Center for Gastroenteritis

Search CenterWatch for Gastroenteritis

Inferred drug relations via UMLS61/NDF-RT41:

Genetic Tests for Gastroenteritis

Anatomical Context for Gastroenteritis

Animal Models for Gastroenteritis or affiliated genes

Sources:
28inGenious Targeting Laboratory
See all sources

Publications for Gastroenteritis

Sources:
51PubMed
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Articles related to Gastroenteritis:

(show top 50)    (show all 867)
idTitleAuthorsYear
1
Surveillance for rotavirus gastroenteritis in children less than 5 years of age in togo. (24343607)
2014
2
Multilevel analysis of childhood nonviral gastroenteritis associated with environmental risk factors in Quebec, 1999-2006. (24288849)
2013
3
Delayed eosinophilic gastroenteritis, a possible side effect of clopidogrel? (23219131)
2013
4
Emergency department revisits in children with gastroenteritis. (23820403)
2013
5
Comparison of 2 assays for diagnosing rotavirus and evaluating vaccine effectiveness in children with gastroenteritis. (23876518)
2013
6
Enhanced enteric virus detection in sporadic gastroenteritis using a multi-target real-time PCR panel: A one-year study. (24242161)
2013
7
Correspondence on "Clinical Characterization of Gastroenteritis-Related Seizures in Children: Impact of Fever and Serum Sodium Levels" (23945928)
2013
8
Nontyphoidal Salmonella Infection in Children with Acute Gastroenteritis: Prevalence, Serotypes, and Antimicrobial Resistance in Shanghai, China. (24313784)
2013
9
Norovirus virus-like particle vaccines for the prevention of acute gastroenteritis. (23414407)
2013
10
Emergence of two novel norovirus genotype II.4 variants associated with viral gastroenteritis in China. (24136475)
2013
11
A comparative study of febrile and afebrile seizures associated with mild gastroenteritis. (23111347)
2013
12
Estimating the excess of inappropriate prescriptions of anti-dopaminergic anti-emetics during acute gastroenteritis epidemics in France. (23935001)
2013
13
Sialic acid binding properties of soluble coronavirus spike (S1) proteins: differences between infectious bronchitis virus and transmissible gastroenteritis virus. (23896748)
2013
14
Effectiveness of rotavirus vaccine in preventing severe acute gastroenteritis in children. (22423021)
2012
15
Pharmacoeconomic spotlight on rotavirus vaccine RIX4414 (Rotarixa8c) in the prevention of rotavirus gastroenteritis in developing countries. (23013458)
2012
16
Burden of community-acquired and nosocomial rotavirus gastroenteritis in the pediatric population of Western Europe: a scoping review. (22429601)
2012
17
In the child with gastroenteritis who is unable to tolerate oral fluids, are there effective alternatives to intravenous hydration? (22560467)
2012
18
Successful treatment of eosinophilic gastroenteritis with clarithromycin. (23269887)
2012
19
Severity of rotavirus gastroenteritis in Indian children requiring hospitalization. (22520127)
2012
20
Transmissible gastroenteritis virus infection induces apoptosis through FasL- and mitochondria-mediated pathways. (22341312)
2012
21
Eosinophilic gastroenteritis: a diagnosis behind the curtains. (23373056)
2012
22
Antibiotics usually inappropriate in children with gastroenteritis. (23316981)
2012
23
Can ondansetron help children with vomiting due to gastroenteritis? (22439191)
2012
24
Changes in hospitalisations for acute gastroenteritis in Australia after the national rotavirus vaccination program. (23072242)
2012
25
Effectiveness of rotavirus vaccination in prevention of hospital admissions for rotavirus gastroenteritis among young children in Belgium: case-control study. (22875947)
2012
26
Complete genome sequence of an astrovirus identified in a domestic rabbit (Oryctolagus cuniculus) with gastroenteritis. (22998755)
2012
27
Travel-associated salmonella and campylobacter gastroenteritis in England: estimation of under-ascertainment through national laboratory surveillance. (22017719)
2011
28
Historical perspective: norovirus gastroenteritis outbreaks in military forces. (22145848)
2011
29
Randomised clinical trial: the synbiotic food supplement Probiotical vs. placebo for acute gastroenteritis in children. (21899583)
2011
30
Host defense against Salmonella and rotaviral gastroenteritis: a serial study of transcriptional factors and cytokines. (18629423)
2008
31
Eosinophilic gastroenteritis: a review. (18958542)
2008
32
Eosinophilic gastroenteritis observed by double balloon enteroscopy and endoscopic ultrasonography in the whole gastrointestinal tract. (19317286)
2008
33
Nephropathy, polyneuropathy, and gastroenteritis in a child with Churg-Strauss syndrome. (16897116)
2007
34
Eosinophilic gastroenteritis and citrus-induced urticaria. (16461997)
2006
35
Eosinophilic gastroenteritis with severe protein-losing enteropathy: successful treatment with budesonide. (16326154)
2006
36
Eosinophilic gastroenteritis associated with systemic lupus erythematosus. (15492606)
2004
37
Oral disodium cromoglycate and ketotifen for a patient with eosinophilic gastroenteritis, food allergy and protein-losing enteropathy. (15032404)
2003
38
Multiple ulcerative lesions of the stomach: a rare case of eosinophilic gastroenteritis. (12397296)
2002
39
Eosinophilic gastroenteritis: our recent experience: one-year experience of atypical onset of an uncommon disease. (11761030)
2001
40
Eosinophilic gastroenteritis mimicking acute appendicitis. (11261632)
2000
41
Eosinophilic gastroenteritis and Anisakis. (9930590)
1998
42
Eosinophilic gastroenteritis involving the entire digestive tract. (7572911)
1995
43
Evidence for an abnormal profile of interleukin-4 (IL-4), IL-5, and gamma-interferon (gamma-IFN) in peripheral blood T cells from patients with allergic eosinophilic gastroenteritis. (7814459)
1994
44
Eosinophilic gastroenteritis in a patient with large-cell anaplastic lung carcinoma: a paraneoplastic syndrome? (7812030)
1994
45
The spectrum of eosinophilic gastroenteritis. Report of six pediatric cases and review of the literature. (1879097)
1991
46
Secretory IgA in nasal secretions of children with acute gastroenteritis and kwashiorkor. (6191630)
1982
47
Transmural eosinophilic gastroenteritis with ascites. (762993)
1979
48
Eosinophilic gastroenteritis: a simple reaction to food allergens? (5486274)
1970
49
Diffuse eosinophilic gastroenteritis. (5775080)
1969
50
Eosinophilic gastroenteritis...with small bowel obstruction. (6041413)
1967

Genetic Variations for Gastroenteritis

Expression for genes affiliated with Gastroenteritis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Gastroenteritis

Search GEO for disease gene expression data for Gastroenteritis.

Pathways for genes affiliated with Gastroenteritis

Sources:
30KEGG, 38NCBI BioSystems Database
See all sources

Pathways related to Gastroenteritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.5IL5, RNASE3, PRG2, CCL11
210.5IL5, IGHE, CCL11

Compounds for genes affiliated with Gastroenteritis

Sources:
45Novoseek, 29IUPHAR, 24HMDB, 11DrugBank, 50PharmGKB, 60Tocris Bioscience, 2BitterDB
See all sources

Compounds related to Gastroenteritis according to GeneCards/GeneDecks:

(show top 50)    (show all 134)
idCompoundScoreTop Affiliating Genes
1histamine45 29 2413.0CCL11, HGF, RNASE3, PRG2, IGHE, IL5
2prednisolone45 29 1113.0IL5, ALB, HGF, CSN1S1, IGHE, RNASE3
3allergens4511.0IGHE, CCL11, CSN3, CSN1S1, PRG2, RNASE3
4lactate4511.0CSN1S1, BTD, RNASE3, SRF, ALB, ANPEP
5arginine4510.9RNASE3, HGF, CSN1S1, PRG2, ANPEP, IGHE
6unicap4510.9IGHE, CCL11, IL5, RNASE3
7sodium cromoglycate4510.9RNASE3, IL5, CCL11, IGHE
8heparin45 29 11 2413.9PRG2, CCL11, RNASE3, SRF, CSN1S1
9pgd24510.9IL5, RNASE3, IGHE, PRG2, CCL11
10cetirizine45 29 11 2413.9IL5, IGHE, CCL11, RNASE3
11methacholine45 1111.9IL5, PRG2, CCL11, IGHE, RNASE3
12alanine4510.9HGF, ALB, CCL11, SRF, BTD, IGHE
13ketotifen45 1111.9IL5, IGHE, CCL11, RNASE3
14retinoic acid45 2411.9PRG2, HGF, IL5, RNASE3, SRF, CSN1S1
15montelukast45 50 29 1113.9CCL11, IL5, IGHE, RNASE3
16pge24510.9RNASE3, CCL11, SRF, IL5, ANPEP, CSN1S1
17sulfamethoxazole45 50 1112.9ALB, IGHE, IL5, LACTB
18ltc44510.9IL5, PRG2, RNASE3, CCL11
19budesonide45 50 1112.9CCL11, RNASE3, IL5, IGHE
20salbutamol45 50 29 11 2414.9IGHE, CCL11, RNASE3, IL5
21indomethacin45 60 29 1113.9ALB, IL5, IGHE, CCL11, HGF, PRG2
22fluticasone propionate45 50 60 1113.9IL5, RNASE3, IGHE, CCL11
23creatinine4510.9ALB, IGHE, SRF, RNASE3, CSN1S1, MDH2
24beclomethasone dipropionate4510.9RNASE3, IL5, IGHE
25anti-histamine4510.9RNASE3, CCL11, IGHE
26thyroxine45 2411.9ANPEP, CSN1S1, ALB, IL5, IGHE
27ovomucoid4510.9IGHE, CSN1S1, IL5
28toluene diisocyanate4510.9IL5, RNASE3, IGHE
29lte44510.9RNASE3, CCL11, IL5
30lactose45 1111.8CSN3, CSN1S1, ANPEP, IL5
31nedocromil sodium4510.8RNASE3, IL5, IGHE
32capsaicin45 2911.8HGF, IGHE, RNASE3, IL5
33genistein45 29 60 2 11 2415.8SRF, CCL11, HGF, CSN1S1, PRG2, IL5
34pranlukast45 29 1112.8RNASE3, CCL11, IL5
35cyclosporin a45 29 6012.8CCL11, HGF, SRF, IL5, RNASE3, IGHE
36ceftriaxone45 1111.8IL5, LACTB, ALB
37dexamethasone45 50 29 1113.8IGHE, SRF, IL5, HGF, CCL11, RNASE3
38vitamin a45 11 2412.8IGHE, CSN1S1, HGF, SRF
39methotrexate45 50 1112.8IGHE, IL5, ALB, HGF, SRF
40praziquantel45 1111.7RNASE3, IGHE, IL5
41agar4510.7IL5, HGF, CSN1S1, LACTB, SRF
42salmeterol45 50 29 1113.7IL5, RNASE3, CCL11
43superoxide45 2411.6MDH2, PRG2, SRF
44penicillin4510.6LACTB, IGHE, IL5
45gliadin4510.6RNASE3, CSN1S1, IGHE
46azelastine45 1111.6RNASE3, IL5, IGHE
47glutamate4510.5SRF, IL5, ANPEP, MDH2, CSN1S1, HGF
48itraconazole45 1111.5CSN1S1, IGHE, IL5
49matrigel4510.4CSN1S1, ANPEP, CCL11
50aspartate4510.2CSN1S1, HGF, MDH2, IGHE, ANPEP, ALB

GO Terms for genes affiliated with Gastroenteritis

Sources:
16Gene Ontology
See all sources

Cellular components related to Gastroenteritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557610.5ALB, CCL11, CSN3, CSN1S1, PRG2, PRB3

Products for genes affiliated with Gastroenteritis

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Sources for Gastroenteritis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet