MCID: GST045
MIFTS: 54

Gastroenteritis malady

Gastrointestinal diseases category
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Summaries for Gastroenteritis

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MedlinePlus:33 Have you ever had the "stomach flu?" what you probably had was gastroenteritis - not a type of flu at all. gastroenteritis is an inflammation of the lining of the intestines caused by a virus, bacteria or parasites. viral gastroenteritis is the second most common illness in the u.s. the cause is often a norovirus infection. it spreads through contaminated food or water, and contact with an infected person. the best prevention is frequent hand washing. symptoms of gastroenteritis include diarrhea, abdominal pain, vomiting, headache, fever and chills. most people recover with no treatment. the most common problem with gastroenteritis is dehydration. this happens if you do not drink enough fluids to replace what you lose through vomiting and diarrhea. dehydration is most common in babies, young children, the elderly and people with weak immune systems. nih: national institute of diabetes and digestive and kidney diseases

MalaCards based summary: Gastroenteritis, also known as cholera morbus, is related to eosinophilic gastroenteritis and esophagitis. An important gene associated with Gastroenteritis is IL5 (interleukin 5 (colony-stimulating factor, eosinophil)), and among its related pathways are IL4-mediated signaling events and Selected targets of GCR alpha. The drug erythromycin pwdr and the compounds unicap and sodium cromoglycate have been mentioned in the context of this disorder. Affiliated tissues include small intestine, kidney and testes.

Disease Ontology:8 A gastrointestinal system infectious disease that involves inflammation of the lining of the stomach and small and large intestines, which is caused by viruses, bacteria, or parasites. chemicals and drugs also cause gastroenteritis. the symptoms include diarrhea, loss of appetite, nausea, vomiting, cramps, and discomfort in the abdomen.

Wikipedia:65 Gastroenteritis or infectious diarrhea is a medical condition from inflammation (\"-itis\") of the... more...

Aliases & Classifications for Gastroenteritis

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Gastroenteritis, Aliases & Descriptions:

Name: Gastroenteritis 8 10 44 33 62
Cholera Morbus 8 62
 
Infectious Colitis, Enteritis and Gastroenteritis 8


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


External Ids:

Disease Ontology8 DOID:2326
NCIt39 C34632
MeSH34 D005759

Related Diseases for Gastroenteritis

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Diseases related to Gastroenteritis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 202)
idRelated DiseaseScoreTop Affiliating Genes
1eosinophilic gastroenteritis31.9IL5, CCL11, CSN1S1
2esophagitis31.1IL5, CCL11
3eosinophilic esophagitis30.9CCL11, IL5
4hypereosinophilic syndrome30.9CCL11, IL5
5eosinophilia30.7CCL11, IL5
6food allergy30.6IL5, CCL11, CSN1S1
7bronchitis30.5IL5, CCL11
8diarrhea30.4ALB, CSN1S1
9eosinophilic pneumonia30.3CCL11, IL5
10asthma30.3CSN1S1, IL5, CCL11
11arthritis30.3ALB, CSN1S1, ANPEP
12dermatitis30.2CCL11, IL5, BTD
13ulcerative colitis30.2ALB
14hepatitis29.9ALB, HGF
15metabolic acidosis29.8BTD, ALB
16liver cirrhosis29.5ALB, HGF, CSN1S1
17atherosclerosis29.5ALB, ANPEP, CCL11
18strongyloidiasis10.5IL5
19common cold10.5CCL11
20folliculitis10.5CCL11
21pellagra10.5CSN1S1
22pancreatitis10.4
23duodenitis10.4
24bronchiolitis10.4IL5, CCL11
25chronic eosinophilic pneumonia10.4CCL11, IL5
26giant papillary conjunctivitis10.4CCL11, IL5
27allergic conjunctivitis10.4CCL11, IL5
28keratoconjunctivitis10.4IL5, CCL11
29pulmonary eosinophilia10.3CCL11, IL5
30protein-losing enteropathy10.3
31vernal keratoconjunctivitis10.3IL5, CCL11
32sinusitis10.3CCL11, IL5
33irritable bowel syndrome10.3
34bullous pemphigoid10.3IL5, CCL11
35mycosis fungoides10.3IL5, ANPEP
36malaria10.3ALB
37cutaneous t cell lymphoma10.3IL5, ANPEP
38reactive arthritis10.3
39colitis10.3
40pyloric stenosis10.3
41blindness10.3
42atopic dermatitis10.2CCL11, CSN1S1
43phenylketonuria10.2BTD, CSN1S1
44acute pancreatitis10.2
45cryptosporidiosis10.2
46acute diarrhea10.2
47listeriosis10.2
48duodenal obstruction10.2
49dysentery10.2
50atopy10.2IL5, CCL11, CSN1S1

Graphical network of the top 20 diseases related to Gastroenteritis:



Diseases related to gastroenteritis

Symptoms for Gastroenteritis

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Drugs & Therapeutics for Gastroenteritis

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Drug clinical trials:

Search ClinicalTrials for Gastroenteritis

Search NIH Clinical Center for Gastroenteritis

Inferred drug relations via UMLS62/NDF-RT40:

Genetic Tests for Gastroenteritis

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Anatomical Context for Gastroenteritis

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MalaCards organs/tissues related to Gastroenteritis:

32
Small intestine, Kidney, Testes, Colon, Liver, Bone, Pancreas, T cells, Bone marrow, Eye, Lung, Thyroid, Skin, Tonsil, Pituitary, Neutrophil

Animal Models for Gastroenteritis or affiliated genes

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Publications for Gastroenteritis

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Articles related to Gastroenteritis:

(show top 50)    (show all 899)
idTitleAuthorsYear
1
Severe acute rotavirus gastroenteritis in children less than 5 years in southern ghana: 2006-2011. (24343622)
2014
2
Hospital-based Surveillance for Rotavirus Gastroenteritis in Children Younger Than 5 Years of Age in Ethiopia: 2007-2012. (24343610)
2014
3
Faecal microbiota composition and host-microbe cross-talk following gastroenteritis and in postinfectious irritable bowel syndrome. (24310267)
2013
4
Intestinal amebiasis: a concerning cause of acute gastroenteritis among hospitalized lebanese children. (24404551)
2013
5
Neonatal eosinophilic gastroenteritis: possible in utero sensitization to cow's milk protein. (23985469)
2013
6
Genome sequence of a novel virus of the species human adenovirus d associated with acute gastroenteritis. (23405334)
2013
7
Multilevel analysis of childhood nonviral gastroenteritis associated with environmental risk factors in Quebec, 1999-2006. (24288849)
2013
8
High similarity of novel orthoreovirus detected in a child hospitalized with acute gastroenteritis to mammalian orthoreoviruses found in bats in Europe. (24025904)
2013
9
Canine parvovirus type 2c identified from an outbreak of severe gastroenteritis in a litter in Sweden. (24016358)
2013
10
Comment on "Viral acute gastroenteritis: clinical and epidemiological features of co-infected patients". (23332443)
2013
11
Prevalence of 10 human polyomaviruses in fecal samples from children with acute gastroenteritis: a case-control study. (23824769)
2013
12
Management strategies in the treatment of neonatal and pediatric gastroenteritis. (24194646)
2013
13
The effects of montelukast on eosinophilic gastroenteritis in a mouse model. (23240855)
2013
14
Delayed eosinophilic gastroenteritis, a possible side effect of clopidogrel? (23219131)
2013
15
Effectiveness of rotavirus vaccine in preventing severe acute gastroenteritis in children. (22423021)
2012
16
Antiviral activity of zinc salts against transmissible gastroenteritis virus in vitro. (22818659)
2012
17
Astrovirus gastroenteritis in hospitalized children of less than 5 years of age in Taiwan, 2009. (22209687)
2012
18
Risk factors for salmonella gastroenteritis in children less than five years of age in Taiwan. (22935864)
2012
19
An outbreak of Salmonella Typhimurium phage type 135a gastroenteritis linked to eggs served at an Australian Capital Territory cafAc. (23186240)
2012
20
Gastroenteritis outbreak associated with faecal shedding of canine norovirus in a Portuguese kennel following introduction of imported dogs from Russia. (22151979)
2012
21
Acute gastroenteritis. (23118314)
2012
22
Prevalence of severe acute rotavirus gastroenteritis and intussusceptions in Ghanaian children under 5 years of age. (22337844)
2012
23
Efficacy of a pentavalent human-bovine reassortant rotavirus vaccine against rotavirus gastroenteritis among American Indian children. (22252206)
2012
24
Gastric ulcer and gastroenteritis caused by Epstein-Barr virus during immunosuppressive therapy for a child with systemic juvenile idiopathic arthritis. (22589331)
2012
25
Eosinophilic gastroenteritis: a rare case report. (22912948)
2012
26
Antiemetic treatment for acute gastroenteritis in children: an updated Cochrane systematic review with meta-analysis and mixed treatment comparison in a Bayesian framework. (22815462)
2012
27
Genetic characterization of sapovirus detected in hospitalized children with acute gastroenteritis in Korea. (23289192)
2012
28
Increased prevalence of rotavirus among children associated gastroenteritis in Riyadh Saudi Arabia. (22176997)
2011
29
Resolution of eosinophilic gastroenteritis after resection of uterine leiomyomas. (22009412)
2011
30
Travel-associated salmonella and campylobacter gastroenteritis in England: estimation of under-ascertainment through national laboratory surveillance. (22017719)
2011
31
Reactive arthritis in a population exposed to an extensive waterborne gastroenteritis outbreak after sewage contamination in Pirkanmaa, Finland. (21679096)
2011
32
Molecular techniques in ecohealth research toolkit: facilitating estimation of aggregate gastroenteritis burden in an irrigated periurban landscape. (22146856)
2011
33
A shift in the clinical spectrum of eosinophilic gastroenteritis toward the mucosal disease type. (20451664)
2010
34
Food allergy and eosinophilic gastroenteritis and colitis. (20431371)
2010
35
Central diabetes insipidus misdiagnosed as acute gastroenteritis in a pediatric patient. (18826743)
2008
36
Tumor necrosis factor-alpha and interleukin-10 in viral and bacterial gastroenteritis in children. (15984817)
2005
37
Gastric pseudopolyps in eosinophilic gastroenteritis. (15625432)
2005
38
Eosinophilic gastroenteritis: epidemiology, diagnosis and management. (12175271)
2002
39
Eosinophilic gastroenteritis in children-report of one case. (11826918)
2001
40
Amplified fragment length polymorphism analysis of Campylobacter jejuni strains isolated from chickens and from patients with gastroenteritis or Guillain-BarrAc or Miller Fisher syndrome. (10966409)
2000
41
Interleukin 3, granulocyte-macrophage colony-stimulating factor, and interleukin 5 in eosinophilic gastroenteritis. (8608886)
1996
42
Eosinophilic gastroenteritis manifesting with ascites. (8091267)
1994
43
Oral administration of cromolyn in a patient with protein-losing enteropathy, food allergy, and eosinophilic gastroenteritis. (8170195)
1994
44
Eosinophilic gastroenteritis. (1770565)
1991
45
Eosinophilic gastroenteritis: a description of a new case with serous affectation. (3328515)
1987
46
Eosinophilic gastroenteritis. (6886944)
1983
47
Dysentery form gastroenteritis in infancy. (6275330)
1981
48
Eosinophilic gastroenteritis in extreme allergy. Immunopathological comparison with nonallergic gastrointestinal disease. (456850)
1979
49
Eosinophilic gastroenteritis. (4231978)
1967
50
Eosinophilic gastroenteritis. Two cases with incidental hiatus hernia. (6046691)
1967

Variations for Gastroenteritis

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Expression for genes affiliated with Gastroenteritis

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Expression patterns in normal tissues for genes affiliated with Gastroenteritis

Search GEO for disease gene expression data for Gastroenteritis.

Pathways for genes affiliated with Gastroenteritis

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Pathways related to Gastroenteritis according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.8IL5, CCL11
29.8IL5, CCL11
3
Show member pathways
9.5ALB, HGF
49.3IL5, ANPEP

Compounds for genes affiliated with Gastroenteritis

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Compounds related to Gastroenteritis according to GeneCards/GeneDecks:

(show top 50)    (show all 113)
idCompoundScoreTop Affiliating Genes
1unicap4410.1CCL11, IL5
2sodium cromoglycate4410.0IL5, CCL11
3lte44410.0CCL11, IL5
45-oxoete4410.0IL5, CCL11
5cetirizine44 28 24 1112.9CCL11, IL5
6roxithromycin44 28 1111.9IL5, CCL11
7optison449.9ALB, HGF
8ovomucoid449.9IL5, CSN1S1
9hepaplastin449.8ALB, HGF
10tween 80449.8ALB, CSN1S1
11icodextrin44 1110.8ALB, CSN1S1
12allergens449.6CCL11, CSN1S1, IL5
13ceftriaxone44 1110.6IL5, ALB
14dextran sulfate449.6IL5, HGF, ALB
15herbimycin a44 6110.5IL5, HGF, CCL11
16isotretinoin44 1110.5BTD, CSN1S1, HGF
17diclofenac44 28 50 1112.5CSN1S1, ALB, IL5
18polyacrylic acid449.5ANPEP, CSN1S1
19salicylic acid44 2810.5ALB, CSN1S1, IL5
20pranlukast44 28 1111.5IL5, CCL11
21sodium nitroprusside449.5HGF, CSN1S1, IL5
22hyaluronic acid44 2410.3CCL11, ALB, HGF
23imatinib44 50 1111.2IL5, HGF, ALB
24tacrolimus44 50 1111.2ALB, IL5, CCL11, HGF
25indomethacin44 28 61 1112.2IL5, CCL11, ALB, HGF
26sb 20358044 6110.2CSN1S1, IL5, CCL11, HGF
27lactose44 1110.2CSN1S1, IL5, ANPEP
28ly294002449.2CSN1S1, HGF, IL5, CCL11
29genistein44 28 61 2 24 1114.2CCL11, CSN1S1, HGF, IL5
30hydrocortisone44 2 61 1112.1IL5, ANPEP, HGF
31morphine44 50 28 1112.1IL5, ANPEP, CSN1S1
32vitamin d449.0CSN1S1, HGF, ALB, IL5
33polyethylene glycol449.0CSN1S1, ALB, ANPEP
34folate448.9HGF, CSN1S1, ALB
35testosterone44 61 24 1111.7ALB, HGF, CSN1S1, IL5
36matrigel448.7HGF, ANPEP, CCL11, CSN1S1
37prednisolone44 28 1110.7CCL11, ALB, CSN1S1, HGF, IL5
38histamine44 28 2410.7IL5, CSN1S1, CCL11, ALB, HGF
39thyroxine44 249.7ANPEP, IL5, CSN1S1, ALB
40aspartate448.5ALB, HGF, CSN1S1, ANPEP
41pge2448.4HGF, ANPEP, CCL11, IL5, CSN1S1
42arginine448.3HGF, CSN1S1, IL5, ANPEP, BTD
43retinoic acid44 249.3CSN1S1, CCL11, IL5, HGF, ANPEP
44cysteine448.2BTD, ANPEP, IL5, CSN1S1, ALB
45lactate448.2HGF, ANPEP, BTD, CSN1S1, ALB
46tyrosine448.0BTD, ANPEP, CCL11, IL5, HGF, CSN1S1
47serine447.9CSN1S1, HGF, IL5, ANPEP, BTD
48heparin44 28 24 1110.9ANPEP, CCL11, IL5, HGF, CSN1S1, ALB
49alanine447.8HGF, BTD, ALB, CSN1S1, CCL11, ANPEP
50calcium44 50 24 1110.5SCN1B, CCL11, ALB, CSN1S1, HGF, ANPEP

GO Terms for genes affiliated with Gastroenteritis

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Cellular components related to Gastroenteritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:0310939.5ALB, HGF
2extracellular spaceGO:0056158.1CCL11, IL5, HGF, ALB, BTD
3extracellular regionGO:0055767.1BTD, ALB, CSN1S1, HGF, IL5, CCL11

Biological processes related to Gastroenteritis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1platelet degranulationGO:0025769.5ALB, HGF
2positive regulation of peptidyl-tyrosine phosphorylationGO:0507319.4HGF, IL5

Products for genes affiliated with Gastroenteritis

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Sources for Gastroenteritis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet