Aliases & Classifications for Gastroparesis

MalaCards integrated aliases for Gastroparesis:

Name: Gastroparesis 12 29 52 42 14 69
Gastroparesis Syndrome 12
Gastroparalysis 12
Gastric Atonia 12

Classifications:



External Ids:

Disease Ontology 12 DOID:11914
ICD10 33 K31.84
ICD9CM 35 536.3
MeSH 42 D018589
NCIt 47 C80512
UMLS 69 C0152020

Summaries for Gastroparesis

MalaCards based summary : Gastroparesis, also known as gastroparesis syndrome, is related to stomach disease and brittle diabetes, and has symptoms including hemiplegia, ophthalmoplegia and paresis. An important gene associated with Gastroparesis is MLN (Motilin), and among its related pathways/superpathways are Peptide ligand-binding receptors and cAMP signaling pathway. The drugs Domperidone and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include small intestine, testes and pancreas, and related phenotypes are Decreased viability and behavior/neurological

Wikipedia : 72 Gastroparesis (GP also called delayed gastric emptying) is a medical condition consisting of a paresis... more...

Related Diseases for Gastroparesis

Diseases related to Gastroparesis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 98)
id Related Disease Score Top Affiliating Genes
1 stomach disease 10.8
2 brittle diabetes 10.8
3 progressive supranuclear palsy-progressive non-fluent aphasia syndrome 10.6 ABCB1 CYP2D6
4 teebi kaurah syndrome 10.5 CYP2D6 DRD2
5 placental insufficiency 10.5 MLN MLNR
6 chorea gravidarum 10.4 CYP2D6 DRD2
7 lynch syndrome 10.4 MLN MLNR
8 intussusception 10.2 ABCB1 CCK
9 volkmann contracture 10.2 GAST GHSR
10 chronic tympanitis 10.2 CCK DRD2
11 perianal skin paget's disease 10.2 GAST GHRL
12 adenocarcinoma in situ 10.2 CCK GAST
13 tamoxifen-related endometrial lesion 10.2 CCK GAST
14 dyspepsia 10.1
15 iris mixed cell melanoma 10.1 CCK GAST
16 nutritional optic neuropathy 10.1 GAST GHRL MLN
17 perianal hematoma 10.0 CCK GAST MLN
18 bile duct cystadenocarcinoma 10.0 CCK GAST MLN
19 multiple synostoses syndrome 3 10.0 CCK GAST
20 male reproductive system disease 10.0 CCK GAST MLN
21 allergic urticaria 9.9 CCK GHRL
22 personality disorder 9.9 CCK CYP2D6 DRD2
23 hypersomnia 9.9 ABCB1 CCK
24 neuronitis 9.9
25 neuropathy 9.9
26 pancreatitis 9.9
27 obesity 9.9
28 constipation 9.8
29 perinatal necrotizing enterocolitis 9.8 CCK DRD2 GHRL
30 autonomic dysfunction 9.8
31 esophagitis 9.8
32 dysphagia 9.8
33 lung cancer 9.8
34 acquired aneurysmal subarachnoid hemorrhage 9.7 CYP2D6 GAST HTR3A
35 gastroesophageal reflux 9.7
36 pancreatic cancer 9.7
37 autonomic neuropathy 9.7
38 demyelinating disease 9.7
39 gastroduodenitis 9.7
40 morbid obesity 9.7
41 achalasia 9.7
42 intestinal pseudo-obstruction 9.7
43 atrial fibrillation 9.7
44 biliary dyskinesia 9.7
45 cystic fibrosis 9.7
46 pauci-immune glomerulonephritis with anca 9.6 DRD2 HTR3A
47 mucositis 9.5
48 myopathy 9.5
49 ataxia 9.5
50 polyradiculopathy 9.5

Graphical network of the top 20 diseases related to Gastroparesis:



Diseases related to Gastroparesis

Symptoms & Phenotypes for Gastroparesis

UMLS symptoms related to Gastroparesis:


hemiplegia, ophthalmoplegia, paresis, signs and symptoms, digestive, lassitude, persistent vomiting

GenomeRNAi Phenotypes related to Gastroparesis according to GeneCards Suite gene sharing:

26
id Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00381-A-1 9.17 GHSR HTR3A MLN
2 Decreased viability GR00381-A-2 9.17 GHSR
3 Decreased viability GR00381-A-3 9.17 MLN GHSR HTR3A

MGI Mouse Phenotypes related to Gastroparesis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.76 ABCB1 ADRA1D CCK DRD2 GHRL GHSR
2 digestive/alimentary MP:0005381 9.43 ABCB1 DRD2 GAST GHRL GHSR NOS1
3 endocrine/exocrine gland MP:0005379 9.17 ABCB1 CCK DRD2 GAST GHRL HTR3A

Drugs & Therapeutics for Gastroparesis

Drugs for Gastroparesis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 183)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Domperidone Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 57808-66-9 3151
2
Dopamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-61-6, 62-31-7 681
3
Esomeprazole Approved, Investigational Phase 4 161796-78-7, 119141-88-7 4594 9579578
4
Omeprazole Approved, Investigational, Vet_approved Phase 4 73590-58-6 4594
5
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
6
Hydrocortisone Approved, Vet_approved Phase 4,Phase 2 50-23-7 5754 657311
7
Tadalafil Approved, Investigational Phase 4,Phase 2 171596-29-5 110635
8
Ticagrelor Approved Phase 4 274693-27-5 9871419
9
Haloperidol Approved Phase 4 52-86-8 3559
10
Exenatide Approved, Investigational Phase 4 141758-74-9 15991534
11 Mosapride Investigational Phase 4 112885-41-3
12
Butyric Acid Experimental Phase 4,Phase 2 107-92-6 264
13 Anticoagulants Phase 4
14 Antiemetics Phase 4,Phase 3,Phase 2,Phase 1
15 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1
16 Calcium, Dietary Phase 4
17 Chelating Agents Phase 4
18 Dopamine Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Dopamine Antagonists Phase 4,Phase 3,Phase 2,Phase 1
20 Gastrointestinal Agents Phase 4,Phase 3,Phase 2,Phase 1
21 Neurotransmitter Agents Phase 4,Phase 3,Phase 2,Phase 1
22 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1
23
Serotonin Phase 4,Phase 3,Phase 2,Phase 1 50-67-9 5202
24 Serotonin Agents Phase 4,Phase 3,Phase 2
25 glucagon Phase 4
26 Glucagon-Like Peptide 1 Phase 4
27 Antacids Phase 4,Phase 1
28 Anti-Ulcer Agents Phase 4,Phase 1
29
Proton pump inhibitors Phase 4
30 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2
31 Hormones Phase 4,Phase 1,Phase 2
32 Incretins Phase 4,Phase 1,Phase 2
33 Cortisol succinate Phase 4,Phase 2
34 Hydrocortisone 17-butyrate 21-propionate Phase 4,Phase 2
35 Hydrocortisone acetate Phase 4,Phase 2
36 Hydrocortisone-17-butyrate Phase 4,Phase 2
37 Central Nervous System Depressants Phase 4,Phase 2
38 Psychotropic Drugs Phase 4,Phase 3,Phase 2
39 Hormone Antagonists Phase 4,Phase 2,Phase 1
40 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 2,Phase 1
41 Hypoglycemic Agents Phase 4,Phase 2,Phase 3,Phase 1
42 Phosphodiesterase 5 Inhibitors Phase 4,Phase 2
43 Phosphodiesterase Inhibitors Phase 4,Phase 2
44 Vasodilator Agents Phase 4,Phase 2
45 Analgesics Phase 4,Phase 2
46 Analgesics, Non-Narcotic Phase 4
47 Antipyretics Phase 4
48 Antipsychotic Agents Phase 4,Phase 2
49 Tranquilizing Agents Phase 4,Phase 2
50 decanoic acid Phase 4

Interventional clinical trials:

(show top 50) (show all 221)

id Name Status NCT ID Phase Drugs
1 Prucalopride Versus Placebo in Gastroparesis Unknown status NCT02510976 Phase 4 prucalopride;placebo
2 Effects and Mechanism of Mosapride Citrate on Diabetic Gastroparesis Unknown status NCT02264587 Phase 4 Mosapride;domperidone
3 Glucagon Like Peptides Receptors Expression in the Stomach of Diabetes Type 2 Unknown status NCT00473733 Phase 4
4 Gastric Functions & Proton Pump Inhibitor( PPI) Study Unknown status NCT00951431 Phase 4 Esomeprazole;Placebo
5 Pharmacokinetics of Immediate-Release vs. Delayed-Release Omeprazole in Gastroparesis Completed NCT00492622 Phase 4 Immediate-release omeprazole;Delayed-release omeprazole
6 Limited Access Protocol for the Use of Oral Cisapride Completed NCT02524496 Phase 4
7 Early Oral Versus Enteral Nutrition After Pancreatoduodenectomy Recruiting NCT01642875 Phase 4
8 Impairment of Gastric Emptying During Acute Phase of Myocardial Infarction. Impact on Oral Antiplatelet Treatment Efficacy. The GASTRIM Study. Recruiting NCT02251249 Phase 4 Paracetamol concentration time curve from 0 to 120 min
9 Hydrocortisone vs. Pasireotide in Preventing Pancreatic Surgery Complications Recruiting NCT02775227 Phase 4 Hydrocortisone;Pasireotide
10 An Efficacy and Safety Study of Cisapride in Patients With Chronic Gastroparesis After Failure of Other Treatment Options Terminated NCT01281540 Phase 4 Cisapride;Placebo
11 An Efficacy and Safety Study of Cisapride for Improving Symptoms Associated With Gastroparesis in Patients With Diabetes Mellitus Terminated NCT01286090 Phase 4 Cisapride;Placebo
12 Haloperidol vs Conventional Therapy for Gastroparesis Terminated NCT02057549 Phase 4 Haloperidol;Conventional Therapy
13 Effect of Tegaserod on Gastric Emptying in Patients With Diabetic Gastroparesis Terminated NCT00390975 Phase 4 Tegaserod
14 Enterra Therapy Gastric Stimulation System Terminated NCT00556166 Phase 4
15 An Exploratory Study on the Effects of Repeat Doses of Albiglutide Compared to Exenatide on Gastric Myoelectrical Activity and Gastric Emptying in Type 2 Diabetes Mellitus Subjects Terminated NCT02793154 Phase 4 Exenatide;Albiglutide
16 Gastric vs Jejunal Feeding in Diabetic Gastroparesis Withdrawn NCT00944593 Phase 4
17 Daily Tadalafil and Gastric Emptying Time in Diabetic Gastroparesis Withdrawn NCT01326117 Phase 4 tadalafil
18 Sancuso® for Gastroparesis: An Open Label Study. Unknown status NCT01989221 Phase 3 Sancuso®
19 Effect of Electroacupuncture in Diabetic Patients With Gastroparesis Unknown status NCT00227383 Phase 3
20 A Prospective Randomized Controlled Multicenter Trial of Delayed Gastric Emptying (DGE) After Pancreaticoduodenectomy Evaluating by Gastrointestinal Reconstruction Unknown status NCT01460550 Phase 3
21 Nortriptyline for Idiopathic Gastroparesis Completed NCT00765895 Phase 3 Nortriptyline Hydrochloride;Placebo (for nortriptyline)
22 Temporary Gastric Electrical Stimulation for Drug Refractory Gastroparesis Completed NCT00432835 Phase 3
23 Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Women With Diabetic Gastroparesis Completed NCT02025725 Phase 3 Metoclopramide Nasal Spray;Placebo Nasal Spray
24 Multicenter Study to Evaluate the Efficacy and Safety of Metoclopramide Nasal Spray in Men With Diabetic Gastroparesis Completed NCT02025751 Phase 3 Metoclopramide Nasal Spray;Placebo Nasal Spray
25 Aprepitant for the Relief of Nausea in Patients With Chronic Nausea and Vomiting of Presumed Gastric Origin Trial Completed NCT01149369 Phase 3 Aprepitant;Placebo
26 Using Magnetic Resonance (MR) to Understand the Effect of Erythromycin on Bowel Motility Completed NCT01379183 Phase 2, Phase 3 Erythromycin;Placebo
27 A Safety and Efficacy Study of Relamorelin in Diabetic Gastroparesis Recruiting NCT03285308 Phase 3 Relamorelin;Placebo
28 Prucalopride Versus Placebo in Gastroparesis Recruiting NCT02031081 Phase 2, Phase 3 Prucalopride;Placebo
29 Treatment Protocol for the Compassionate Use of Domperidone Recruiting NCT01696734 Phase 3 Domperidone
30 Cattell-Warren Versus Blumgart Techniques of Pancreatico-jejunostomy Following Pancreato-duodenectomy Recruiting NCT02457156 Phase 3 Octreotide
31 Anti-inflammatory Effect of Peroperative Stimulation of the Vagus Nerve Recruiting NCT02524626 Phase 3
32 Per-oral Endoscopy Pyloromyotomy (G-POEM) in the Treatment of Refractory Diabetic Gastroparesis : Prospective Evaluation of Efficacy Not yet recruiting NCT02927886 Phase 3
33 REinforcement of the Pancreas in distaL pAncreatectomY (REPLAY) Not yet recruiting NCT03030170 Phase 3
34 Acupuncture for Diabetic Gastroparesis Suspended NCT00470795 Phase 3
35 Effects of Pulsatile Insulin Delivery on Diabetic Neuropathy in Patients With Types 1 and 2 Diabetes Mellitus Terminated NCT00228891 Phase 2, Phase 3
36 The Use of Domperidone for Gastroparesis Withdrawn NCT01378884 Phase 3 Domperidone
37 Comparison Study for Bile Reflux and Gastric Stasis in Patients After Distal Gastrectomy Withdrawn NCT00622804 Phase 3
38 Effects of Pulsatile Intravenous Insulin Delivery on Diabetic Neuropathy in pATIENTS (Pts) With Type 1 and Type 2 Diabetes Withdrawn NCT00228904 Phase 2, Phase 3
39 Drug Trial of Lixisenatide on Gastric Emptying and Blood Pressure Drops in Type 2 Diabetics and Healthy People Unknown status NCT02308254 Phase 1, Phase 2 Lixisenatide;Placebo
40 Cannabis for Inflammatory Bowel Disease Unknown status NCT01040910 Phase 1, Phase 2 smoking of cannabis;smoking cigarettes with placebo
41 Orthostatic Dysregulation and Associated Gastrointestinal Dysfunction in Parkinson's Disease -Treatment Unknown status NCT01993680 Phase 2 Pyridostigmine bromide;fludrocortisone
42 The Use of a Restrictive Fluid Regimen With Hypertonic Saline for Patients Undergoing Pancreaticoduodenectomy Unknown status NCT01428050 Phase 2 3% NaCl Solution;Lactated Ringers Solution
43 External Drainage Versus Internal Drainage of Pancreatic Duct With a Stent After Pancreaticoduodenectomy (EDIDPD) Unknown status NCT01634971 Phase 2
44 Acupuncture Treatment for Gastroparesis: a Pilot Study Completed NCT01643577 Phase 1, Phase 2
45 The Diabetic and Idiopathic Gastroparesis Efficacy, Safety, and Tolerability (DIGEST) Study Completed NCT02267525 Phase 2 Velusetrag;Placebo
46 A Study to Evaluate the Effect of Camicinal on Gastroparesis Symptoms in Type 1 and 2 Diabetic Subjects With Gastroparesis Completed NCT02210000 Phase 2 Placebo;Camicinal
47 Safety and Efficacy of IV Infusion of Investigational Agent (TZP-101) in Patients With Severe Diabetic Gastroparesis Completed NCT00612014 Phase 2 5% dextrose in water;TZP-101;TZP-101;TZP-101;TZP-101;TZP-101
48 Safety and Efficacy of Once-daily Oral Administrations of TZP-102 for Gastroparesis in Patients With Diabetes Mellitus Completed NCT00889486 Phase 2 TZP-102;Placebo
49 Trial of IW-9179 in Patients With Diabetic Gastroparesis (DGP) Completed NCT02289846 Phase 2 IW-9179;Matching Placebo
50 Phase 2 Study of Velusetrag in Diabetic or Idiopathic Gastroparesis Completed NCT01718938 Phase 2 velusetrag dose 1;velusetrag dose 2;velusetrag dose 3;placebo

Search NIH Clinical Center for Gastroparesis

Inferred drug relations via UMLS 69 / NDF-RT 48 :


Cochrane evidence based reviews: gastroparesis

Genetic Tests for Gastroparesis

Genetic tests related to Gastroparesis:

id Genetic test Affiliating Genes
1 Gastroparesis 29

Anatomical Context for Gastroparesis

MalaCards organs/tissues related to Gastroparesis:

39
Small Intestine, Testes, Pancreas, Lung, Colon, Heart, Kidney

Publications for Gastroparesis

Articles related to Gastroparesis:

(show top 50) (show all 650)
id Title Authors Year
1
A quantified risk-scoring system and rating model for postsurgical gastroparesis syndrome in gastric cancer patients. ( 28743171 )
2017
2
Exploration of the psychosocial issues associated with gastroparesis: A qualitative investigation. ( 28071866 )
2017
3
Relating gastric scintigraphy and symptoms to motility capsule transit and pressure findings in suspected gastroparesis. ( 28872760 )
2017
4
Effectiveness and feasibility of robotic gastric neurostimulator placement in patients with refractory gastroparesis. ( 28730536 )
2017
5
Healthcare utilization and costs associated with gastroparesis. ( 28706426 )
2017
6
Efficacy and Safety of Relamorelin in Diabetics with Symptoms of Gastroparesis:A Randomized, Placebo-Controlled Study. ( 28760384 )
2017
7
Understanding the Differences Between Gastroparesis and Gastroparesis-Like Syndrome: Filling a GaPing Hole? ( 28776142 )
2017
8
Endoscopic Pyloromyotomy for the Treatment of Severe Refractory Diabetic Gastroparesis. ( 28050040 )
2017
9
POEMs for gastroparesis. ( 27986106 )
2017
10
Diabetic and idiopathic gastroparesis is associated with loss of CD206-positive macrophages in the gastric antrum. ( 28066953 )
2017
11
Yield of Endoscopy in Pediatric Gastroparesis. ( 28644345 )
2017
12
Functional dyspepsia and gastroparesis. ( 28832359 )
2017
13
Gastroparesis: Medical and Therapeutic Advances. ( 28721575 )
2017
14
The Long-Term Efficacy and Safety of Pyloroplasty Combined with Gastric Electrical Stimulation Therapy in Gastroparesis. ( 27896652 )
2017
15
Radiation induced gastroparesis-case report and literature review. ( 28890828 )
2017
16
Impaired insulin/IGF-1 is responsible for diabetic gastroparesis by damaging myenteric cholinergic neurons and interstitial cells of Cajal. ( 28931726 )
2017
17
Randomized Controlled Double-blind Trial Comparing Haloperidol Combined With Conventional Therapy to Conventional Therapy Alone in Patients With Symptomatic Gastroparesis. ( 28646590 )
2017
18
Gastric peroral endoscopic myotomy for gastroparesis, after botulinum toxin injection. ( 28759929 )
2017
19
"First Do No Harm": Adverse Events from Pharmaceutical Treatment of Gastroparesis and Dyspepsia. ( 28932929 )
2017
20
Vitamin C Improves Gastroparesis in Diabetic Rats: Effects on Gastric Contractile Responses and Oxidative Stress. ( 28639130 )
2017
21
Gastric per-oral endoscopic pyloromyotomy in the treatment of refractory gastroparesis: Report on the first case performed in Mexico. ( 28684033 )
2017
22
Tailored approach to gastroparesis significantly improves symptoms. ( 28779255 )
2017
23
Gastric peroral endoscopic pyloromyotomy as a salvage therapy for refractory gastroparesis: a case series of different subtypes. ( 28028897 )
2017
24
Modified Laparoscopic Pyloroplasty During Laparoscopic Splenectomy and Azygoportal Disconnection for the Prevention of Postoperative Gastroparesis. ( 28689488 )
2017
25
Laparoscopic treatment of gastroparesis: a single center experience. ( 28888796 )
2017
26
Is There a Role for Enterohormones in the Gastroparesis of Critically Ill Patients? ( 28737574 )
2017
27
Endoscopic ultrasonography-guided intrapyloric injection of botulinum toxin to treat diabetic gastroparesis. ( 27556873 )
2016
28
The Association Between Fasting C-peptide and Gastrointestinal Symptoms of Gastroparesis in Type 2 Diabetic Patients. ( 27820956 )
2016
29
Upper Gastrointestinal Tract Motility Disorders in Women, Gastroparesis, and Gastroesophageal Reflux Disease. ( 27261896 )
2016
30
Systematic review and meta-analysis: Gastric electrical stimulation for gastroparesis. ( 27085627 )
2016
31
Is Gastroparesis Found More Frequently in Patients with Cystic Fibrosis? A Systematic Review. ( 27313953 )
2016
32
Immunomodulation for treatment of drug and device refractory gastroparesis. ( 27014566 )
2016
33
Innovative gastric endoscopic muscle biopsy to identify all cell types, including myenteric neurons and interstitial cells of Cajal in patients with idiopathic gastroparesis: a feasibility study (with video). ( 27129395 )
2016
34
Per-oral endoscopic pyloromyotomy and per-oral endoscopic myotomy for coexisting refractory gastroparesis and recurrent achalasia cardia in a single patient. ( 27090287 )
2016
35
Towards a better drug for gastroparesis- the problem with a "moving" target. ( 27215652 )
2016
36
Gastric Enterovirus Infection: A Possible Causative Etiology of Gastroparesis. ( 27344315 )
2016
37
Levothyroxine Tablet Malabsorption Associated with Gastroparesis Corrected with Gelatin Capsule Formulation. ( 27293919 )
2016
38
Profound opiate toxicity in gastroparesis following therapeutic dose. ( 27147632 )
2016
39
Early satiety and postprandial fullness in gastroparesis correlate with gastroparesis severity, gastric emptying, and water load testing. ( 27781342 )
2016
40
Granisetron Transdermal System for Treatment of Symptoms of Gastroparesis: A Prescription Registry Study. ( 27400689 )
2016
41
Nausea and vomiting in gastroparesis: similarities and differences in idiopathic and diabetic gastroparesis. ( 27350152 )
2016
42
Evaluation of gastric blood supply in diabetic patients with gastroparesis by contrast-enhanced ultrasound. ( 27759430 )
2016
43
Gastric emptying and symptoms: functional dyspepsia versus gastroparesis. ( 27106678 )
2016
44
Acute Slow Wave Responses to High-Frequency Gastric Electrical Stimulation in Patients With Gastroparesis Defined by High-Resolution Mapping. ( 27284964 )
2016
45
Pancreatic Adenocarcinoma Invading the Duodenum and Presenting as Idiopathic Gastroparesis with Nausea and Vomiting. ( 27807571 )
2016
46
Effect of electroacupuncture on gastric interstitial cells of Cajal in a rat model of diabetic gastroparesis. ( 27284337 )
2016
47
Gastroparesis in a patient with Parkinson's disease. ( 27166113 )
2016
48
The Management of Gastroparesis Associated Malnutrition. ( 27111029 )
2016
49
Safety of treatment for gastroparesis. ( 27031006 )
2016
50
The impact of gastroparesis on diabetes control: Patient perceptions. ( 27166926 )
2016

Variations for Gastroparesis

Expression for Gastroparesis

Search GEO for disease gene expression data for Gastroparesis.

Pathways for Gastroparesis

GO Terms for Gastroparesis

Cellular components related to Gastroparesis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 axon GO:0030424 8.92 CCK DRD2 GHRL HTR3A

Biological processes related to Gastroparesis according to GeneCards Suite gene sharing:

(show all 20)
id Name GO ID Score Top Affiliating Genes
1 signal transduction GO:0007165 9.99 ADRA1D CCK DRD2 GAST GHSR MLNR
2 response to cocaine GO:0042220 9.59 DRD2 HTR3A
3 negative regulation of blood pressure GO:0045776 9.58 DRD2 NOS1
4 hormone-mediated signaling pathway GO:0009755 9.58 GHRL GHSR
5 decidualization GO:0046697 9.57 GHRL GHSR
6 response to food GO:0032094 9.56 GAST GHSR
7 regulation of sodium ion transport GO:0002028 9.55 DRD2 NOS1
8 adenylate cyclase-activating adrenergic receptor signaling pathway GO:0071880 9.54 ADRA1D DRD2
9 actin polymerization or depolymerization GO:0008154 9.52 GHRL GHSR
10 adult feeding behavior GO:0008343 9.49 GHRL GHSR
11 negative regulation of interleukin-1 beta production GO:0032691 9.48 GHRL GHSR
12 positive regulation of growth hormone secretion GO:0060124 9.46 DRD2 GHRL
13 growth hormone secretion GO:0030252 9.4 GHRL GHSR
14 negative regulation of tumor necrosis factor biosynthetic process GO:0042536 9.37 GHRL GHSR
15 positive regulation of multicellular organism growth GO:0040018 9.33 DRD2 GHRL GHSR
16 negative regulation of interleukin-6 biosynthetic process GO:0045409 9.32 GHRL GHSR
17 positive regulation of appetite GO:0032100 9.26 GHRL GHSR
18 G-protein coupled receptor signaling pathway GO:0007186 9.17 ADRA1D DRD2 GAST GHRL GHSR MLN
19 negative regulation of appetite GO:0032099 9.13 CCK
20 negative regulation of insulin secretion GO:0046676 9.13 DRD2 GHRL GHSR

Molecular functions related to Gastroparesis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 adrenergic receptor activity GO:0004935 9.16 ADRA1D DRD2
2 growth hormone-releasing hormone receptor activity GO:0016520 8.96 GHSR MLNR
3 hormone activity GO:0005179 8.92 CCK GAST GHRL MLN

Sources for Gastroparesis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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