MCID: GST009
MIFTS: 43

Gastroschisis malady

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Gastroschisis

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Aliases & Descriptions for Gastroschisis:

Name: Gastroschisis 11 48 50 39 13 68
Congenital Fissure of the Abdominal Cavity 48
 
Laparoschisis 48

Classifications:



External Ids:

Disease Ontology11 DOID:11044
ICD1030 Q79.3
ICD9CM32 756.73
SNOMED-CT62 72951007
MeSH39 D020139
NCIt45 C84725

Summaries for Gastroschisis

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NIH Rare Diseases:48 Gastroschisis is a birth defect that occurs when a baby's intestines extend outside of the body through a hole next to the belly button. This type of defect is known as an abdominal wall defect. Sometimes other organs are also involved.   The exact cause of a gastroschisis is usually not known, but it is more common in babies born to young mothers or to mothers who may have used alcohol or tobacco during their pregnancies. Gastroschisis is typically diagnosed on routine ultrasound examinations before a baby is born. These babies may need to be born in hospitals with specialists who are experienced in treating gastroschisis. Treatment includes a special kind of surgery that gradually returns the intestines to the abdomen (silo repair). Prognosis depends primarily on the degree of injury to the bowel, and on the presence of other birth defects. Though long-term outcomes for babies born with simple gastroschisis are generally good, some children may have problems with digestion later in life. Complications from gastroschisis can include intestinal problems, breathing difficulties, and infection. Some cases of gastroschisis may resolve in utero, with closure of the hole of the abdominal wall, resulting in strangulation and destruction of the herniated bowel (vanishing gastroschisis or vanishing gut syndrome), and very short-bowel syndrome. Other complications include incomplete bowel (atresia), destruction (necrosis), perforation or twisting (volvulos). The prognosis of these cases is poor, but detecting these problems during pregnancy (antenatal diagnosis) and having fetal intervention may improve the outcome in the future. Last updated: 11/21/2016

MalaCards based summary: Gastroschisis, also known as congenital fissure of the abdominal cavity, is related to gastroschisis abdominal wall defects, included and abdominal wall defect. An important gene associated with Gastroschisis is AEBP1 (AE Binding Protein 1), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Malaria. Affiliated tissues include skin, liver and small intestine, and related mouse phenotype homeostasis/metabolism.

Wikipedia:71 Gastroschisis represents a congenital defect characterised by a defect in the anterior abdominal wall... more...

Related Diseases for Gastroschisis

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Diseases related to Gastroschisis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 97)
idRelated DiseaseScoreTop Affiliating Genes
1gastroschisis abdominal wall defects, included12.3
2abdominal wall defect11.8
3paraomphalocele10.8
4omphalocele10.6
5prostate leiomyosarcoma10.3IL6, MMP3
6bladder neck cancer10.2IL6, NPPA
7keloids10.2IL6, MMP3
8intestinal atresia10.1
9orbital periostitis10.1IL6, MMP3
10birth defects10.1
11vertebral artery occlusion10.0IL6, MMP3
12corneal intraepithelial neoplasm10.0IL6, MMP8
13neonatal period electroclinical syndrome10.0IL6, MMP8
14sternum lymphoma9.9IL6, MMP3
15actinomycosis9.9IL6, MMP1
16small intestine cancer, childhood9.9MMP1, MMP3
17congenital diaphragmatic hernia9.9
18pathological gambling9.9MMP1, MMP3
19juvenile astrocytoma9.9MMP1, MMP3
20nervous system cancer9.9IL6, MMP8
21retinal degeneration9.8MMP1, MMP3
22short bowel syndrome9.8
23secondary corneal edema9.8MMP1, MMP3
24bardet-biedl syndrome 89.8IL6, MMP1
25salt and pepper syndrome9.8MMP1, MMP3
26pneumoconiosis9.8MMP1, MMP3
27gallbladder lymphoma9.8MMP1, MMP3
28jejunal atresia9.8
29esophagitis9.8
30oligohydramnios9.8
31corpus callosum dysgenesis cleft spasm9.8MMP1, MMP3
32optic atrophy 79.8MMP1, MMP8
33chorioretinitis9.8IL6, MMP3, MMP8
34steroid-induced glaucoma9.8MMP1, MMP3
35mastoiditis9.7IL6, MMP1
36neural tube defects9.7
37prune belly syndrome9.7
38cryptorchidism9.7
39colonic atresia9.7
40craniosynostosis9.7
41orofacial cleft9.7
42gastric dilatation9.7
43ischemia9.7
44neuronitis9.7
45familial nephrotic syndrome9.6BMP1, MMP1, MMP3
46herpetic gastritis9.6MMP1, NPPA, TGFB3
47melorheostosis9.6IL6, MMP1, MMP3
48eosinophilic gastroenteritis9.6IL6, MMP8
49granulomatous orchitis9.6IL6, MMP1, MMP3
50malignant giant cell tumor9.6IL6, MMP1, MMP3

Graphical network of the top 20 diseases related to Gastroschisis:



Diseases related to gastroschisis

Symptoms & Phenotypes for Gastroschisis

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MGI Mouse Phenotypes related to Gastroschisis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053765.8ACHE, ADD1, AEBP1, BMP1, IL6, MMP1

Drugs & Therapeutics for Gastroschisis

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Drugs for Gastroschisis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Metoclopramideapproved, investigationalPhase 3116364-62-54168
Synonyms:
(metaclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
(metoclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
2-Methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide
2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethyl)benzamide
2-Methoxy-5-chloroprocainamide
2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide
2-methoxy-5-chloroprocainamide
2576-84-3 (di-hydrochloride)
364-62-5
4 Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
4-Amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (Mcp)
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (metoclopramide)
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide(Metoclopramide)
4-amino-5-chloro-2-Methoxy-N-(beta-diethylaminoethyl)benzamide
4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-2-methoxybenzamide
4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-O-anisamide
4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide
4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
5-Chloro-2-methoxyprocainamide
54143-57-6 (mono-hydrochloride, mono-hydrate)
7232-21-5 (mono-hydrochloride)
AB00053498
AC1L1HKD
AKOS000280832
ARONIS24307
Apo-Metoclop
BPBio1_000217
BPBio1_001100
BRD-K75641298-001-01-5
BRD-K75641298-003-05-2
BRN 1884366
BSPBio_000197
BSPBio_002027
Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy- (9CI)
Biomol-NT_000082
C07868
C14H22ClN3O2
CAS-7232-21-5
CHEBI:107736
CHEMBL86
CID4168
CLOPRA-"YELLOW"
Cerucal
Clopra
Clopra-Yellow
Clopromate
D00726
DB01233
DEL
DEL 1267
DivK1c_000069
Duraclamid
EINECS 206-662-9
Elieten
Elieten (TN)
Emetid
Emitasol
Emperal
Eucil
Gastrese
Gastro-Timelets
Gastrobid
Gastromax
Gastronerton
Gastrosil
Gastrotablinen
Gastrotem
HMS2089G16
IDI1_000069
Imperan
KBio1_000069
KBio2_002118
 
KBio2_004686
KBio2_007254
KBio3_001527
KBioGR_001307
KBioSS_002118
L001078
LS-20038
Lopac-M-0763
Lopac0_000762
Maxeran
Maxolon
Meclopran
Metaclopramide
Metaclopromide
Metamide
Methochlopramide
Methoclopramide
Metochlopramide
Metoclol
Metoclopramida
Metoclopramida [INN-Spanish]
Metoclopramide (JP15/INN)
Metoclopramide Hcl
Metoclopramide Hydrochloride
Metoclopramide Intensol
Metoclopramide Monohydrochloride, Monohydrate
Metoclopramide Omega
Metoclopramide [INN:BAN:JAN]
Metoclopramidum
Metoclopramidum [INN-Latin]
Metocobil
Metramid
MolPort-000-883-854
Moriperan
Mygdalon
N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide
NCGC00015643-01
NCGC00015643-02
NCGC00015643-03
NCGC00015643-08
NCGC00024440-03
NCGC00024440-04
NCI60_003185
NINDS_000069
Neu-Sensamide
Nu-Metoclopramide
Octamide
Parmid
Paspertin
Peraprin
Plasil
Plasil (pharmaceutical)
Pms-Metoclopramide
Pramidin
Pramiel
Pramin
Prestwick0_000209
Prestwick1_000209
Prestwick2_000209
Prestwick3_000209
Primperan
Reclomide
Reglan
Reliveran
SPBio_001740
SPBio_002118
ST024773
Spectrum2_001720
Spectrum3_000504
Spectrum4_000964
Spectrum5_001449
Spectrum_001638
Terperan
Terperan (TN)
UNII-L4YEB44I46
bmse000779
metoclopramide
o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)- (8CI)
2
DopamineapprovedPhase 3375951-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
3Peripheral Nervous System AgentsPhase 322776
4Neurotransmitter AgentsPhase 317734
5AntiemeticsPhase 33888
6Gastrointestinal AgentsPhase 3, Phase 1, Phase 28109
7Dopamine D2 Receptor AntagonistsPhase 3332
8Dopamine AgentsPhase 33759
9Autonomic AgentsPhase 39774
10Dopamine AntagonistsPhase 31083
11Pharmaceutical SolutionsPhase 27793
12Soybean oil, phospholipid emulsionPhase 273
13Protective AgentsPhase 27190
14Parenteral Nutrition SolutionsPhase 2153
15AntioxidantsPhase 22928
16Fat Emulsions, IntravenousPhase 292
17
BilirubinPhase 2112635-65-45280352
Synonyms:
(4Z,15Z)-Bilirubin IXa
(Z,Z)-Bilirubin IXa
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
 
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Bilirubin
Bilirubin IX-alpha
Cholerythrin
Hematoidin
18Liver ExtractsPhase 23868
19Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 1, Phase 212767
20IncretinsPhase 1, Phase 21537
21HormonesPhase 1, Phase 213979
22Hormone AntagonistsPhase 1, Phase 212778
23glucagonPhase 1, Phase 2462
24Glucagon-Like Peptide 1Phase 1, Phase 2694
25Omega 3 Fatty AcidNutraceuticalPhase 2969
26Soy BeanNutraceuticalPhase 2535
27Micronutrients5802
28Vitamins5095
29Trace Elements5802
30BifidobacteriumNutraceutical230
31lysineNutraceutical90

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1Trial of AMNIOECHANGE in Gastroschisis Affected FoetusesUnknown statusNCT00127946Phase 3
2Metoclopramide Pilot TrialRecruitingNCT02098915Phase 3
3Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine CareActive, not recruitingNCT01884324Phase 2, Phase 3
4Evaluating the Use of a Silastic Spring-Loaded Silo for Infants With GastroschisisCompletedNCT00539292Phase 2
5Compassionate Use of Omegaven in ChildrenRecruitingNCT02370251Phase 2
6Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal FailureTerminatedNCT01573286Phase 1, Phase 2
7Sutureless vs Sutured Gastroschisis ClosureUnknown statusNCT01094587
8Music Therapy: An Adjunct To Gastroschisis Infants' CareUnknown statusNCT01469208
9Probiotics in Infants With GastroschisisUnknown statusNCT01316510
10Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition?Unknown statusNCT01891279
11PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn ChildrenCompletedNCT01296724
12Determination of Lysine Requirement in the Parenterally Fed NeonateCompletedNCT00779753
13Silo Versus Primary Closure for GastroschisisRecruitingNCT01506531
14Clinical and Biological Outcomes of Human Milk and Formula Intake After Gastroschisis RepairRecruitingNCT02575846
15Gastroschisis Outcomes of Delivery (GOOD) StudyNot yet recruitingNCT02774746
16Bedside Silo Versus Operative Closure for GastroschisisTerminatedNCT00404690
17Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in InfantsTerminatedNCT01062815

Search NIH Clinical Center for Gastroschisis


Cochrane evidence based reviews: gastroschisis

Genetic Tests for Gastroschisis

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Anatomical Context for Gastroschisis

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MalaCards organs/tissues related to Gastroschisis:

36
Skin, Liver, Small intestine, Colon, Heart, Smooth muscle, Testis

Publications for Gastroschisis

About this section

Articles related to Gastroschisis:

(show top 50)    (show all 720)
idTitleAuthorsYear
1
Transamniotic stem cell therapy (TRASCET) in a leporine model of gastroschisis. (27836365)
2017
2
Newborn with Gastroschisis associated with Limb Anomalies. (28083494)
2017
3
Chylous Ascites in a Newborn with Gastroschisis. Case Report. (28083502)
2017
4
Closed gastroschisis, vanishing midgut and extreme short bowel syndrome: Case report and review of the literature. (27867410)
2016
5
Oligohydramnios and growth restriction do not portend worse prognosis in gastroschisis pregnancies. (26932657)
2016
6
Gastroschisis with Concomitant Jejuno-Ileal Atresia Complicated by Jejunal Perforation. (27123409)
2016
7
Gastroschisis outcomes in North America: a comparison of Canada and the United States. (27004440)
2016
8
Management and outcome challenges in newborns with gastroschisis: A 6-year retrospective French study. (27892784)
2016
9
Gene variants as risk factors for gastroschisis. (27616475)
2016
10
Closed Gastroschisis with Vanished Small Bowel and Jejunal Atresia. (27896173)
2016
11
Cost modeling for management strategies of uncomplicated gastroschisis. (27621010)
2016
12
Accuracy of antenatal ultrasound signs in predicting the risk for bowel atresia in patients with gastroschisis. (27280540)
2016
13
Neurodevelopment and Health-Related Quality of Life in Infants Born with Gastroschisis: A 6-Year Retrospective French Study. (27931048)
2016
14
Assessing quality of life in pediatric gastroschisis patients using the Pediatric Quality of Life Inventory survey: An institutional study. (26932251)
2016
15
Probiotic Administration in Infants With Gastroschisis: A Pilot Randomized Placebo-Controlled Trial. (27880742)
2016
16
Gastroschisis: mortality risks with each additional week of expectant management. (27596619)
2016
17
Management of gastroschisis. (26974976)
2016
18
Fetal gastroschisis: antepartum fetal heart rate analysis by computerized cardiotocography. (27180816)
2016
19
Relationship between neonatal gastroschisis and maternal body mass index in a United Kingdom population. (28088673)
2016
20
Gastroschisis: Bellwether for neonatal surgery capacity in low resource settings? (27032610)
2016
21
Gastroschisis and maternal intake of phytoestrogens. (27232448)
2016
22
Babies born with gastroschisis and followed up to the age of six years faced long-term morbidity and impairments. (26910581)
2016
23
Outcome differences between simple and complex gastroschisis. (27845942)
2016
24
Intra-Amniotic Hemorrhage Imitating Gastroschisis: A Case Report and Review of the Literature. (27760979)
2016
25
Gastroschisis in Uganda: Opportunities for improved survival. (27516176)
2016
26
Gastroschisis: A Review of Management and Outcomes. (27640608)
2016
27
Flap versus fascial closure for gastroschisis: a systematic review and meta-analysis. (26970850)
2016
28
Gastroschisis Complicated by Septo-Optic Dysplasia: Two Distinct Anomalies with a Common Origin. (26929863)
2016
29
Gastroschisis with gastric perforation and jejunal stenosis. A rare association of anomalies. (26996209)
2016
30
Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis. (27825040)
2016
31
Improved outcomes for inborn babies with uncomplicated gastroschisis. (28017414)
2016
32
Mortality-related factors in gastroschisis - a Jamaican perspective. (27842958)
2016
33
Measuring self-reported quality of life in 8- to 11-year-old children born with gastroschisis: Is the KIDSCREEN questionnaire acceptable? (26931186)
2016
34
High mortality among children with gastroschisis after the neonatal period: A long-term follow-up study. (27665495)
2016
35
Folic acid fortification and prevalences of neural tube defects, orofacial clefts, and gastroschisis in California, 1989 to 2010. (27191125)
2016
36
Geospatial clustering of gastroschisis in Poland: Data from the Polish Registry of Congenital Malformations (PRCM). (26988884)
2016
37
Development of a core outcome set for use in determining the overall success of gastroschisis treatment. (27465672)
2016
38
Spatial variability of gastroschisis in Canada, 2006-2011: An exploratory analysis. (27348112)
2016
39
Excessive Postoperative Fluid Administration in Infants with Gastroschisis. (27657585)
2016
40
Response to Letter to the Editor Regarding "Probiotic Administration in Infants with Gastroschisis: a Pilot Randomized Placebo-controlled Trial". (27579695)
2016
41
Is there a relationship between hospital volume and patient outcomes in gastroschisis repair? (27139881)
2016
42
Antenatal ultrasound features in fetuses with gastroschisis and its prediction in neonatal outcome. (27874184)
2016
43
Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. (27183609)
2016
44
Gastroschisis with gastric perforation and jejunal stenosis A rare association of anomalies. (27345767)
2016
45
Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring. (27856447)
2016
46
Correction: Prevalence of Gastroschisis, Omphalocele, Spina Bifida and Orofacial Clefts of Neonates from January 2000 to December 2010 in Leipzig, Saxony, Saxony-Anhalt and Germany. (27533496)
2016
47
Variability of outcome reporting in Hirschsprung's Disease and gastroschisis: a systematic review. (27941923)
2016
48
What prenatal ultrasound features are predictable of complex or vanishing gastroschisis? A retrospective study. (27981591)
2016
49
Quality of life in patients with gastroschisis is comparable with the general population: A questionnaire survey. (27982137)
2016
50
Perioperative glycaemic control for preterm infant with transient neonatal hyperglycaemia and gastroschisis. (26939866)
2016

Variations for Gastroschisis

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Expression for genes affiliated with Gastroschisis

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Search GEO for disease gene expression data for Gastroschisis.

Pathways for genes affiliated with Gastroschisis

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GO Terms for genes affiliated with Gastroschisis

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Cellular components related to Gastroschisis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1proteinaceous extracellular matrixGO:00055788.2BMP1, MMP1, MMP3, MMP8
2extracellular spaceGO:00056157.2ACHE, AEBP1, BMP1, IL6, MMP3, MMP8
3extracellular regionGO:00055767.1ACHE, BMP1, IL6, MMP1, MMP3, MMP8

Biological processes related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 9)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of pathway-restricted SMAD protein phosphorylationGO:001086210.4BMP1, TGFB3
2positive regulation of DNA replicationGO:004574010.4IL6, TGFB3
3positive regulation of protein secretionGO:005071410.2ACHE, TGFB3
4positive regulation of protein oligomerizationGO:003246110.0MMP1, MMP3
5regulation of apoptotic processGO:00429819.8BMP1, IL6, TGFB3
6regulation of MAPK cascadeGO:00434089.7BMP1, TGFB3
7collagen catabolic processGO:00305749.2MMP1, MMP3, MMP8
8extracellular matrix disassemblyGO:00226178.9BMP1, MMP1, MMP3, MMP8
9proteolysisGO:00065088.8BMP1, MMP1, MMP3, MMP8

Molecular functions related to Gastroschisis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:000512510.1BMP1, IL6, TGFB3
2growth factor activityGO:000808310.1BMP1, IL6, TGFB3
3calcium ion bindingGO:00055098.9BMP1, MMP1, MMP3, MMP8
4metalloendopeptidase activityGO:00042228.9BMP1, MMP1, MMP3, MMP8
5serine-type endopeptidase activityGO:00042528.9BMP1, MMP1, MMP3, MMP8
6zinc ion bindingGO:00082707.9AEBP1, BMP1, MMP1, MMP3, MMP8

Sources for Gastroschisis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet