Gastroschisis disease: Malacards - Research Articles, Symptoms, Drugs, Genes, Clinical Trials

Aliases & Classifications for Gastroschisis

Sources:
¹⁰Disease Ontology, ⁴⁵NIH Rare Diseases, ⁴⁷Novoseek, ¹²DISEASES, ⁵¹Orphanet, ³⁶MeSH, ⁶⁵UMLS, ²⁷ICD10, ²⁹ICD9CM, ⁴²NCIt, ⁵⁹SNOMED-CT, ⁶⁶UMLS via Orphanet, ²⁸ICD10 via Orphanet, ³⁷MESH via Orphanet
See all MalaCards sources

Aliases & Descriptions for Gastroschisis:

Name: Gastroschisis ¹⁰ ⁴⁵ ⁴⁷ ¹² ⁵¹ ³⁶ ⁶⁵

Congenital Fissure of the Abdominal Cavity ⁴⁵

Laparoschisis ⁵¹

Characteristics:

Orphanet epidemiological data:

⁵¹

gastroschisis:
Inheritance: Not applicable; Prevalence: 1-5/10000 (Europe),1-5/10000 (Austria),1-5/10000 (Belgium),1-5/10000 (Croatia),1-5/10000 (Denmark),1-5/10000 (France),1-5/10000 (Germany),1-9/100000 (Hungary),1-5/10000 (Ireland),1-9/100000 (Italy),1-5/10000 (Malta),1-5/10000 (Netherlands),1-5/10000 (Norway),1-5/10000 (Poland),1-5/10000 (Portugal),1-9/100000 (Spain),1-5/10000 (Switzerland),1-5/10000 (United Kingdom),1-9/100000 (Ukraine); Age of onset: Antenatal,Neonatal; Age of death: normal life expectancy

Classifications:

MalaCards categories:
Global: Rare diseases, Fetal diseases
Anatomical: Gastrointestinal diseases

See all MalaCards categories (disease lists)

ICD10: ²⁸ ²⁷

Congenital malformations, deformations and chromosomal abnormalities

Congenital malformations and deformations of the musculoskeletal system

Congenital malformations of the musculoskeletal system, not elsewhere classified

Gastroschisis

Orphanet: ⁵¹

Rare gastroenterological diseases

Developmental anomalies during embryogenesis

External Ids:

Disease Ontology¹⁰ DOID:11044

ICD10²⁷ Q79.3

ICD9CM²⁹ 756.73

MeSH³⁶ D020139

NCIt⁴² C84725

SNOMED-CT⁵⁹ 72951007

Orphanet⁵¹ 2368

UMLS via Orphanet⁶⁶ C0265706

ICD10 via Orphanet²⁸ Q79.3

MESH via Orphanet³⁷ D020139

UMLS⁶⁵ C0265706

Summaries for Gastroschisis

Sources:
⁶⁸Wikipedia, ³³MalaCards
See all MalaCards sources

Wikipedia:⁶⁸ Gastroschisis represents a congenital defect characterised by a defect in the anterior abdominal wall... more...

MalaCards based summary: Gastroschisis, also known as congenital fissure of the abdominal cavity, is related to abdominal wall defect and omphalocele, and has symptoms including gastroschisis, intestinal atresia/stenosis/absence/agenesis/hypoplasia (excludes duodenum) and mesenterium anomaly/common mesentery/mesenteric adhesion. An important gene associated with Gastroschisis is BMP1 (Bone Morphogenetic Protein 1), and among its related pathways are IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types and Immune response_MIF-mediated glucocorticoid regulation. Affiliated tissues include skin, liver and breast, and related mouse phenotypes are muscle and hematopoietic system.

Related Diseases for Gastroschisis

Sources:
²⁰GeneCards, ¹⁹GeneAnalytics
See all MalaCards sources

Diseases related to Gastroschisis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 101)

id	Related Disease	Score	Top Affiliating Genes
1	abdominal wall defect	10.8
2	omphalocele	10.7
3	laparoschisis	10.4
4	crohn's disease	10.4	F5, IL6
5	sugarman brachydactyly	10.4	F5, IL6
6	oral mucosa leukoplakia	10.4	IL6, NPPA
7	maple bark strippers' lung	10.4	F5, IL6
8	eccrine sweat gland neoplasm	10.3	F5, IL6
9	focal embolic glomerulonephritis	10.3	IL6, MPO
10	protein s deficiency	10.3	F5, IL6
11	partial circumpapillary choroid dystrophy	10.3	IL6, MPO
12	idiopathic hypersomnia	10.3	MPO, NPPA
13	intestinal atresia	10.2
14	papillary pattern testicular yolk sac tumor	10.2	F5, MPO
15	cutaneous paget's disease	10.2	F5, IL6
16	oral squamous cell carcinoma	10.2	F5, MPO
17	acute zonal occult outer retinopathy	10.2	F5, IL6
18	signet ring cell variant cervical mucinous adenocarcinoma	10.2	NPPA, TGFB3
19	focal labyrinthitis	10.2	F5, MPO
20	retinitis pigmentosa	10.2	F5, IL6
21	villoglandular variant cervical mucinous adenocarcinoma	10.2	IL6, MPO
22	adult spinal cord glioblastoma multiforme	10.1	F5, IL6
23	fetal erythroblastosis	10.1	F5, MPO
24	childhood kidney angiomyolipoma	10.1	IL6, MPO
25	childhood kidney cell carcinoma	10.1	ICAM1, IL6
26	monckeberg arteriosclerosis	10.1	ICAM1, IL6
27	spinal canal and spinal cord meningioma	10.1	IL6, NPPA, TGFB3
28	parasitic helminthiasis infectious disease	10.0	ICAM1, TGFB3
29	dancing eyes-dancing feet syndrome	10.0	ICAM1, IL6
30	congenital diaphragmatic hernia	10.0
31	dyskinesia of esophagus	10.0	ICAM1, IL6
32	hypopharynx cancer	10.0	ICAM1, IL6
33	pyrimidine metabolic disorder	10.0	ICAM1, IL6
34	keratomalacia	10.0	ICAM1, IL6
35	exudative glomerulonephritis	9.9	ICAM1, MPO
36	angioedema	9.9	ICAM1, MPO
37	crescentic glomerulonephritis	9.9	ICAM1, MPO
38	conduct disorder	9.9	ICAM1, MPO
39	paraomphalocele	9.9
40	qualitative platelet defect	9.9	ICAM1, MPO
41	short bowel syndrome	9.9
42	esophagitis	9.9
43	oligohydramnios	9.9
44	chylous ascites	9.9
45	liver leiomyosarcoma	9.9	F5, IL6, MPO
46	timothy grass allergy	9.9	ICAM1, MPO
47	tuberculoid leprosy	9.8	ICAM1, MPO
48	suppurative uveitis	9.8	ICAM1, MPO
49	conjunctivochalasis	9.8	ICAM1, IL6
50	neural tube defects	9.8

Graphical network of the top 20 diseases related to Gastroschisis:

Symptoms for Gastroschisis

Sources:
⁵¹Orphanet
See all MalaCards sources

Symptoms:

⁵¹

gastroschisis
intestinal atresia/stenosis/absence/agenesis/hypoplasia (excludes duodenum)

mesenterium anomaly/common mesentery/mesenteric adhesion

Drugs & Therapeutics for Gastroschisis

Sources:
⁴⁴NIH Clinical Center, ⁴ClinicalTrials, ⁶Cochrane Library, ⁶⁵UMLS, ⁴³NDF-RT, ¹³DrugBank, ²⁶HMDB, ⁹DGIdb, ⁵³PharmGKB, ³⁰IUPHAR, ⁴⁷Novoseek, ¹BitterDB
See all MalaCards sources

Drugs for Gastroschisis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Metoclopramide

approved, investigational

Phase 3

102

364-62-5

4168

Synonyms:

(metaclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

(metoclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one

2-Methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide

2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethyl)benzamide

2-Methoxy-5-chloroprocainamide

2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide

2-methoxy-5-chloroprocainamide

2576-84-3 (di-hydrochloride)

364-62-5

4 Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

4-Amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide

4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (Mcp)

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (metoclopramide)

4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide(Metoclopramide)

4-amino-5-chloro-2-Methoxy-N-(beta-diethylaminoethyl)benzamide

4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-2-methoxybenzamide

4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-O-anisamide

4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide

4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide

5-Chloro-2-methoxyprocainamide

54143-57-6 (mono-hydrochloride, mono-hydrate)

7232-21-5 (mono-hydrochloride)

AB00053498

AC1L1HKD

AKOS000280832

ARONIS24307

Apo-Metoclop

BPBio1_000217

BPBio1_001100

BRD-K75641298-001-01-5

BRD-K75641298-003-05-2

BRN 1884366

BSPBio_000197

BSPBio_002027

Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy- (9CI)

Biomol-NT_000082

C07868

C14H22ClN3O2

CAS-7232-21-5

CHEBI:107736

CHEMBL86

CID4168

CLOPRA-"YELLOW"

Cerucal

Clopra

Clopra-Yellow

Clopromate

D00726

DB01233

DEL

DEL 1267

DivK1c_000069

Duraclamid

EINECS 206-662-9

Elieten

Elieten (TN)

Emetid

Emitasol

Emperal

Eucil

Gastrese

Gastro-Timelets

Gastrobid

Gastromax

Gastronerton

Gastrosil

Gastrotablinen

Gastrotem

HMS2089G16

IDI1_000069

Imperan

KBio1_000069

KBio2_002118

KBio2_004686

KBio2_007254

KBio3_001527

KBioGR_001307

KBioSS_002118

L001078

LS-20038

Lopac-M-0763

Lopac0_000762

Maxeran

Maxolon

Meclopran

Metaclopramide

Metaclopromide

Metamide

Methochlopramide

Methoclopramide

Metochlopramide

Metoclol

Metoclopramida

Metoclopramida [INN-Spanish]

Metoclopramide

Metoclopramide (JP15/INN)

Metoclopramide Hcl

Metoclopramide Hydrochloride

Metoclopramide Intensol

Metoclopramide Monohydrochloride, Monohydrate

Metoclopramide Omega

Metoclopramide [INN:BAN:JAN]

Metoclopramidum

Metoclopramidum [INN-Latin]

Metocobil

Metonia

Metramid

MolPort-000-883-854

Moriperan

Mygdalon

N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide

NCGC00015643-01

NCGC00015643-02

NCGC00015643-03

NCGC00015643-08

NCGC00024440-03

NCGC00024440-04

NCI60_003185

NINDS_000069

Neu-Sensamide

Nu-Metoclopramide

Octamide

Parmid

Paspertin

Peraprin

Plasil

Plasil (pharmaceutical)

Pms-Metoclopramide

Pramidin

Pramiel

Pramin

Prestwick0_000209

Prestwick1_000209

Prestwick2_000209

Prestwick3_000209

Primperan

Reclomide

Reglan

Reliveran

SPBio_001740

SPBio_002118

ST024773

Spectrum2_001720

Spectrum3_000504

Spectrum4_000964

Spectrum5_001449

Spectrum_001638

Terperan

Terperan (TN)

UNII-L4YEB44I46

bmse000779

metoclopramide

o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)- (8CI)

2

Dopamine

approved

Phase 3

3084

62-31-7, 51-61-6

681

Synonyms:

(3H)-Dopamine

.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride

.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane

1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)

1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride

1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium

153C5321-5FEE-4B0B-8925-F388F0EEEBD1

2-(3,4-Dihydroxyphenyl)ethylamine

2-(3,4-dihydroxyphenyl)ethylamine

2-benzenediol

3,4-Dihydroxyphenethylamine

3,4-Dihydroxyphenethylamine hydrochloride

3,4-Dihydroxyphenylethylamine

3,4-dihydroxyphenethylamine

3-Hydroxtyramine

3-Hydroxytyramine

3-Hydroxytyramine Hydrobromide

3-Hydroxytyramine hydrochloride

4-(2-Aminoethyl)-1,

4-(2-Aminoethyl)-1,2-benzenediol

4-(2-Aminoethyl)-1,2-bezenediol

4-(2-Aminoethyl)-Pyrocatechol

4-(2-Aminoethyl)benzene-1,2-diol

4-(2-Aminoethyl)catechol

4-(2-Aminoethyl)pyrocatechol

4-(2-Aminoethyl)pyrocatechol hydrochloride

4-(2-aminoethyl)-pyrocatechol

50444-17-2

51-61-6

62-31-7 (HYDROCHLORIDE)

AC1L19S5

AC1Q54AX

AC1Q54AY

AKOS003790978

ASL 279

BIDD:ER0506

BPBio1_001123

BSPBio_001932

Biomol-NT_000001

C03758

CHEBI:18243

CHEMBL59

CID681

D07870

DB00988

Deoxyepinephrine

DivK1c_000780

Dopamin

Dopamina

Dopamina [INN-Spanish]

Dopamine

Dopamine (INN)

Dopamine (USAN)(*hydrochloride*)

Dopamine Hcl

Dopamine Hydrochloride

Dopamine [INN:BAN]

Dopaminum

Dopaminum [INN-Latin]

Dopastat

Dophamine

Dynatra

EINECS 200-110-0

HSDB 3068

Hydroxytyramin

Hydroxytyramine

IDI1_000780

IP 498

Intropin

Intropin [*hydrochloride*]

KBio1_000780

KBio2_001492

KBio2_002388

KBio2_002484

KBio2_004060

KBio2_004956

KBio2_005052

KBio2_006628

KBio2_007524

KBio2_007620

KBio3_001152

KBio3_002867

KBio3_002962

KBioGR_001129

KBioGR_002388

KBioGR_002484

KBioSS_001492

KBioSS_002393

KBioSS_002491

KW-3-060

L-DOPAMINE

L000232

LDP

LS-159

Lopac-H-8502

Lopac0_000586

Medopa (TN)

MolPort-001-641-000

NCGC00015519-01

NCGC00015519-08

NCGC00096050-01

NCGC00096050-02

NCGC00096050-03

NCGC00096050-04

NCGC00096050-05

NINDS_000780

NSC 173182

NSC169105

NSC173182

Oprea1_088821

Oxytyramine

Pyrocatechol, 4-(2-aminoethyl)- (8CI)

Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride

Revimine

Revivan

SPBio_001205

SPECTRUM1505155

ST048774

STK301601

Spectrum2_001023

Spectrum3_000406

Spectrum4_000525

Spectrum5_000945

Spectrum_001012

UNII-VTD58H1Z2X

UPCMLD0ENAT5885989:001

a-(3,4-Dihydroxyphenyl)-b-aminoethane

alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane

cMAP_000036

cMAP_000065

dopamine

hydroxytyramine

intropin

m-Hydroxytyramine hydrochloride

nchembio.105-comp9

nchembio.107-comp4

nchembio.284-comp1

nchembio.78-comp16

nchembio.89-comp3

nchembio705-8

nchembio801-comp8

3

Neurotransmitter Agents

Phase 3

14795

4

Antiemetics

Phase 3

3213

5

Gastrointestinal Agents

Phase 3, Phase 1, Phase 2

6401

6

Peripheral Nervous System Agents

Phase 3

18510

7

Dopamine D2 Receptor Antagonists

Phase 3

258

8

Dopamine Agents

Phase 3

3084

9

Dopamine Antagonists

Phase 3

927

10

Fat Emulsions, Intravenous

Phase 2

29

11

Liver Extracts

Phase 2

3572

12

Bilirubin

Phase 2

103

635-65-4

5280352

Synonyms:

(4Z,15Z)-Bilirubin IXa

(Z,Z)-Bilirubin IXa

1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate

1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid

2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate

2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid

3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate

3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid

3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene

3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate

3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid

3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate

3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid

Bilirubin

Bilirubin IX-alpha

Cholerythrin

Hematoidin

13

Hormone Antagonists

Phase 1, Phase 2

10002

14

Hormones

Phase 1, Phase 2

11748

15

Glucagon-Like Peptide 1

Phase 1, Phase 2

620

16

glucagon

Phase 1, Phase 2

379

17

Hormones, Hormone Substitutes, and Hormone Antagonists

Phase 1, Phase 2

9988

18

Incretins

Phase 1, Phase 2

1326

19

Omega 3 Fatty Acid

Nutraceutical

Phase 2

912

20

Soy Bean

Nutraceutical

Phase 2

455

21

Trace Elements

3900

22

Vitamins

3857

23

Pharmaceutical Solutions

7004

24

Micronutrients

3901

25

lysine

Nutraceutical

77

26

Bifidobacterium

Nutraceutical

213

Interventional clinical trials:

(show all 17)

id	Name	Status	NCT ID	Phase
1	Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine Care	Recruiting	NCT01884324	Phase 2, Phase 3
2	Metoclopramide Pilot Trial	Recruiting	NCT02098915	Phase 3
3	Trial of AMNIOECHANGE in Gastroschisis Affected Foetuses	Active, not recruiting	NCT00127946	Phase 3
4	Evaluating the Use of a Silastic Spring-Loaded Silo for Infants With Gastroschisis	Completed	NCT00539292	Phase 2
5	Compassionate Use of Omegaven in Children	Recruiting	NCT02370251	Phase 2
6	Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal Failure	Terminated	NCT01573286	Phase 1, Phase 2
7	PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn Children	Completed	NCT01296724
8	Determination of Lysine Requirement in the Parenterally Fed Neonate	Completed	NCT00779753
9	Silo Versus Primary Closure for Gastroschisis	Recruiting	NCT01506531
10	Sutureless vs Sutured Gastroschisis Closure	Recruiting	NCT01094587
11	Music Therapy: An Adjunct To Gastroschisis Infants' Care	Recruiting	NCT01469208
12	Probiotics in Infants With Gastroschisis	Recruiting	NCT01316510
13	Clinical and Biological Outcomes of Human Milk and Formula Intake After Gastroschisis Repair	Recruiting	NCT02575846
14	Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition?	Recruiting	NCT01891279
15	Gastroschisis Outcomes of Delivery (GOOD) Study	Not yet recruiting	NCT02774746
16	Bedside Silo Versus Operative Closure for Gastroschisis	Terminated	NCT00404690
17	Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in Infants	Terminated	NCT01062815

Search NIH Clinical Center for Gastroschisis

Cochrane evidence based reviews: gastroschisis

Genetic Tests for Gastroschisis

Anatomical Context for Gastroschisis

Sources:
³³MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Gastroschisis:

³³

Skin, Liver, Breast, Kidney, Heart, Brain, Lung

Animal Models for Gastroschisis or affiliated genes

Sources:
³⁸MGI
See all MalaCards sources

MGI Mouse Phenotypes related to Gastroschisis:

³⁸

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	muscle	MP:0005369	8.0	BMP1, ICAM1, IL6, MPO, NPPA
2	hematopoietic system	MP:0005397	7.6	ADD1, BMP1, ICAM1, IL6, MPO, NPPA
3	cardiovascular system	MP:0005385	6.7	BMP1, F5, ICAM1, IL6, MPO, NPPA
4	homeostasis/metabolism	MP:0005376	6.1	ADD1, BMP1, F5, ICAM1, IL6, MPO

Publications for Gastroschisis

Sources:
⁵⁴PubMed
See all MalaCards sources

Articles related to Gastroschisis:

(show top 50) (show all 684)

id	Title	Authors	Year
1	Oligohydramnios and growth restriction do not portend worse prognosis in gastroschisis pregnancies. (26932657)	Johnston R.... Haeri S.	2016
2	Gastroschisis with Concomitant Jejuno-Ileal Atresia Complicated by Jejunal Perforation. (27123409)	Zvizdic Z.	2016
3	Sonographic markers associated with adverse neonatal outcomes among fetuses with gastroschisis: An eleven year, single-center review. (26454131)	Sinkey R.G.... Warshak C.R.	2015
4	Isolated prenatal ultrasound findings predict the postnatal course in gastroschisis. (25697276)	Frybova B.... Rygl M.	2015
5	Feeding Intolerance and Poor Growth in Infants with Gastroschisis: Longitudinal Experience with Consecutive Patients over Thirteen Years. (26500852)	Balgi S.... Batton B.	2015
6	Prenatal examination and postmortem findings in fetuses with gastroschisis and omphalocele. (24604302)	Faugstad T.M.... Vogt C.	2014
7	Anomalies associated with gastroschisis and omphalocele: analysis of 2825 cases from the Texas Birth Defects Registry. (24726103)	Benjamin B.... Wilson G.N.	2014
8	Prevalence and risk factors for gastroschisis in a public hospital from west MAcxico. (25243388)	Robledo-Aceves M.... Corona-Rivera J.R.	2014
9	Gastroschisis, omphalocele or something else? (23531629)	Chan L.C.... Ng P.C.	2014
10	Left-sided Gastroschisis: A Rare Congenital Anomaly. (24298510)	Mandelia A.... Panda S.	2013
11	Gastric contractility in experimental gastroschisis. (23414860)	Cavalcante M.B.... Melo-Filho A.A.	2013
12	Human milk versus formula after gastroschisis repair: effects on time to full feeds and time to discharge. (23519369)	Kohler J.A.... Bass W.T.	2013
13	Expectant management compared with elective delivery at 37 weeks for gastroschisis. (23635735)	Baud D.... Ryan G.	2013
14	Gastroschisis, destructive brain lesions, and placental infarction in the second trimester suggest a vascular pathogenesis. (23895144)	Folkerth R.D.... Elliott A.J.	2013
15	Left-sided gastroschisis with placenta findings: case report and literature review. (22558479)	Shi Y.... Carpenter P.M.	2012
16	Evolution of critically ill patients with gastroschisis from three tertiary centers. (21437430)	Tannuri A.C.... Camperoni A.L.	2011
17	Assessing the trend of gastroschisis prevalence in China from 1996 to 2007 using two analytical methods. (21308975)	Xu L.... Zhu J.	2011
18	Ultrasound prediction of birthweight and growth restriction in fetal gastroschisis. (20723876)	Chaudhury P.... Goodnight W.H.	2010
19	Changes in amniotic fluid index after maternal oral hydration in pregnancies with fetal gastroschisis: initial observations. (20606383)	Brizot M.L.... Zugaib M.	2010
20	Evisceration and necrosis of gall bladder and evisceration of urinary bladder in a patient of gastroschisis. (20098013)	Mirza B.... Sheikh A.	2010
21	Benchmarking the quality of care of infants with low-risk gastroschisis using a novel risk stratification index. (20236674)	Chang D.C.... Abdullah F.	2010
22	Perinatal demography of gastroschisis in North Queensland. (21166913)	Whitehall J.S.... Gill A.	2010
23	Gastroschisis associated with an intra-abdominal umbilical vein varix: a report of 2 cases. (19786788)	Fung T.Y.... Lau T.K.	2009
24	Escape of the yolk sac: a hypothesis to explain the embryogenesis of gastroschisis. (19419415)	Stevenson R.E.... Hunter A.G.	2009
25	Spontaneous sutureless closure of the abdominal wall defect in gastroschisis using a commercial wound retractor system. (19705131)	Ogasawara Y.... Yamataka A.	2009
26	Re: M. B. Forrester and R. D. Merz (2006), Comparison of trends in gastroschisis and prenatal illicit drug use rates. J. Toxicol. Environ. Health A 69:1253-1259. (18080905)	Chabra S.	2008
27	Rare case of fetal gastroschisis with aplasia of the foot and external genital organs. (18778459)	Rao S.R.... Rao A.V.	2008
28	Anaesthetic management of gastroschisis - a review of our practice over the past 5 years. (18613932)	Raghavan M.... Montgomerie J.	2008
29	Novel intra-operative pulse oximetry monitoring for gastroschisis: a noninvasive monitor of intra-abdominal pressure. (18315652)	Hong C.M.... Patel A.	2008
30	Fetal abdominal wall repair with a collagen biomatrix in an experimental sheep model for gastroschisis. (18636946)	Roelofs L.A.... Wijnen R.M.	2008
31	Scheduled preterm delivery for gastroschisis improves postoperative outcome. (18668252)	Gelas T.... DuBois R.	2008
32	Non-genetic risk factors for gastroschisis. (18655102)	Rasmussen S.A.... FrA-as J.L.	2008
33	Outcomes in neonatal gastroschisis: an institutional experience. (17992713)	Vachharajani A.J.... Mathur A.M.	2007
34	Ruptured omphalocele with extracorporeal intestines mimicking gastroschisis in a fetus with Turner syndrome. (17694577)	Chen C.P.	2007
35	Outcomes of pregnancies with fetal gastroschisis. (17766615)	Santiago-Munoz P.C.... Dashe J.S.	2007
36	Splanchnic perfusion pressure: a better predictor of safe primary closure than intraabdominal pressure in neonatal gastroschisis. (16677879)	McGuigan R.M.... Azarow K.S.	2006
37	Does gastroschisis reduction require general anesthesia? A comparative analysis. (16818066)	Cauchi J.... Gornall P.	2006
38	Erythropoietin restores bowel damage and hypoperistalsis in gastroschisis. (16481250)	Ozdamar A.... Hosgor M.	2006
39	Primary fascial closure in 112 infants with gastroschisis. (16146253)	Thepcharoennirund S.	2005
40	A "plastic" sutureless abdominal wall closure in gastroschisis. (15137009)	Sandler A.... Soper R.	2004
41	Fetal home monitoring for the prenatal management of gastroschisis. (15488122)	Salomon L.J.... Dommergues M.	2004
42	Isolated gastroschisis in successive siblings: a case report and review of the literature. (15193205)	Snelling C.M.... Davies G.A.	2004
43	Gastroschisis: the effect of labor and ruptured membranes on neonatal outcome. (14710097)	Strauss R.A.... McMahon M.J.	2003
44	An unusual case of gastroschisis with gallbladder evisceration and late postrepair chylous ascites. (9434035)	Drinnen D.... Filston H.C.	1997
45	Omphalocele and gastroschisis in Europe: a survey of 3 million births 1980-1990. EUROCAT Working Group. (8533813)	Calzolari E.... Milan M.	1995
46	Abdominal wall defects: omphalocele and gastroschisis (continuing education credit). (2961975)	Frentner S.	1987
47	Omphalocele, hernia of the umbilical cord and gastroschisis. (6232916)	Verco P.W.	1983
48	Congenital abdominal wall defects: gastroschisis and omphalocele. (6211335)	Grosfeld J.L.... Weber T.R.	1982
49	Perinatal aspects of omphalocele and gastroschisis. (930890)	Colombani P.M.... Cunningham M.D.	1977
50	(15070122)

Genes related to Gastroschisis

Sources:
²⁰GeneCards, ¹²DISEASES
See all MalaCards sources

Genes related to Gastroschisis:

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication
1	BMP1	Bone Morphogenetic Protein 1	22.04	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
2	ADD1	Adducin 1	21.91	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
3	IL6	Interleukin 6	21.09	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
4	TGFB3	Transforming Growth Factor Beta 3	20.90	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
5	NPPA	Natriuretic Peptide A	20.85	DISEASES inferred ¹² GeneCards inferred via : Publications (show sections)
6	MPO	Myeloperoxidase	17.32	GeneCards inferred via : Publications (show sections)
7	NAT2	N-Acetyltransferase 2 (Arylamine N-Acetyltransferase)	17.32	GeneCards inferred via : Publications (show sections)
8	ICAM1	Intercellular Adhesion Molecule 1	17.32	GeneCards inferred via : Publications (show sections)
9	F5	Coagulation Factor V	17.32	GeneCards inferred via : Publications (show sections)

Variations for Gastroschisis

Expression for genes affiliated with Gastroschisis

Sources:
¹⁷Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Gastroschisis.

Pathways for genes affiliated with Gastroschisis

Sources:
⁵²PathCards, ⁵⁶R&D Systems, ⁶²Thomson Reuters, ³¹KEGG, ⁵⁵QIAGEN, ³⁹NCBI BioSystems Database
See all MalaCards sources

Pathways related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 11)

id	Super pathways	Score	Top Affiliating Genes
1	IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types⁵⁶	9.7	IL6, TGFB3
2	Immune response_MIF-mediated glucocorticoid regulation⁶²	9.3	ICAM1, IL6
3	African trypanosomiasis³¹	9.3	ICAM1, IL6
4	LDL Oxidation in Atherogenesis⁵⁵	9.1	ICAM1, MPO
5	HTLV-I infection³¹	8.9	ICAM1, IL6, TGFB3
6	AGE-RAGE signaling pathway in diabetic complications³¹	8.9	ICAM1, IL6, TGFB3
7	IgA-Producing B Cells in the Intestine⁵⁶	8.9	ICAM1, IL6, TGFB3
8	Malaria³¹	8.9	ICAM1, IL6, TGFB3
9	Rheumatoid arthritis³¹	8.9	ICAM1, IL6, TGFB3
10	amb2 Integrin signaling³⁹	8.8	ICAM1, IL6, MPO
11	Selenium Pathway³⁹ Show member pathways thioredoxin pathway³⁹	8.8	ICAM1, IL6, MPO

GO Terms for genes affiliated with Gastroschisis

Sources:
¹⁸Gene Ontology
See all MalaCards sources

Biological processes related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 9)

id	Name	GO ID	Score	Top Affiliating Genes
1	response to insulin	GO:0032868	10.1	IL6, NPPA
2	wound healing	GO:0042060	10.1	IL6, TGFB3
3	cell growth	GO:0016049	10.0	IL6, TGFB3
4	regulation of MAPK cascade	GO:0043408	9.9	BMP1, TGFB3
5	positive regulation of nitric oxide biosynthetic process	GO:0045429	9.8	ICAM1, IL6
6	response to amino acid	GO:0043200	9.6	ICAM1, IL6
7	positive regulation of ERK1 and ERK2 cascade	GO:0070374	9.3	ICAM1, IL6
8	aging	GO:0007568	9.2	IL6, MPO, TGFB3
9	cellular protein metabolic process	GO:0044267	9.2	ADD1, F5, NPPA