MCID: GST009
MIFTS: 47

Gastroschisis malady

Categories: Rare diseases, Gastrointestinal diseases

Aliases & Classifications for Gastroschisis

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Aliases & Descriptions for Gastroschisis:

Name: Gastroschisis 11 48 50 39 13 68
Congenital Fissure of the Abdominal Cavity 48
 
Laparoschisis 48

Classifications:



External Ids:

Disease Ontology11 DOID:11044
ICD1030 Q79.3
ICD9CM32 756.73
SNOMED-CT62 72951007
MeSH39 D020139
NCIt45 C84725

Summaries for Gastroschisis

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NIH Rare Diseases:48 Gastroschisis is a birth defect that occurs when a baby's intestines extend outside of the body through a hole next to the belly button. this type of defect is known as an abdominal wall defect. sometimes other organs are also involved.   the exact cause of a gastroschisis is usually not known, but it is more common in babies born to young mothers or to mothers who may have used alcohol or tobacco during their pregnancies. gastroschisis is typically diagnosed on routine ultrasound examinations before a baby is born. these babies may need to be born in hospitals with specialists who are experienced in treating gastroschisis. treatment includes a special kind of surgery that gradually returns the intestines to the abdomen (silo repair). prognosis depends primarily on the degree of injury to the bowel, and on the presence of other birth defects. though long-term outcomes for babies born with simple gastroschisis are generally good, some children may have problems with digestion later in life. complications from gastroschisis can include intestinal problems, breathing difficulties, and infection. some cases of gastroschisis may resolve in utero, with closure of the hole of the abdominal wall, resulting in strangulation and destruction of the herniated bowel (vanishing gastroschisis or vanishing gut syndrome), and very short-bowel syndrome. other complications include incomplete bowel (atresia), destruction (necrosis), perforation or twisting (volvulos). the prognosis of these cases is poor, but detecting these problems during pregnancy (antenatal diagnosis) and having fetal intervention may improve the outcome in the future. last updated: 11/21/2016

MalaCards based summary: Gastroschisis, also known as congenital fissure of the abdominal cavity, is related to gastroschisis abdominal wall defects, included and abdominal wall defect, and has symptoms including gastroschisis, intestinal atresia and abnormality of mesentery morphology. An important gene associated with Gastroschisis is AEBP1 (AE Binding Protein 1), and among its related pathways are Differentiation Pathway and IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types. Affiliated tissues include skin, liver and small intestine, and related mouse phenotypes are hematopoietic system and homeostasis/metabolism.

Wikipedia:71 Gastroschisis represents a congenital defect characterised by a defect in the anterior abdominal wall... more...

Related Diseases for Gastroschisis

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Diseases related to Gastroschisis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 93)
idRelated DiseaseScoreTop Affiliating Genes
1gastroschisis abdominal wall defects, included12.3
2abdominal wall defect11.8
3paraomphalocele10.8
4omphalocele10.6
5intestinal atresia10.1
6leber congenital amaurosis10.1MMP1, TGFB3
7birth defects10.1
8acquired thrombocytopenia10.1IL6, MMP1
9mosaic variegated aneuploidy syndrome 210.0MMP1, MMP8
10hereditary night blindness10.0IL6, MMP1
11chronic diarrhea due to guanylate cyclase 2c overactivity10.0MMP1, MMP8
12leukoplakia of vagina10.0IL6, MMP8
13peripheral vascular disease10.0MMP1, MMP8
14kidney leiomyosarcoma10.0IL6, MMP3
15symmastia10.0MMP1, MMP3
16kleptomania10.0MMP1, MMP3
17cystic lymphangioma10.0MMP1, MMP3
18angiomyoma9.9MMP1, MMP3
19vitreoretinopathy, neovascular inflammatory9.9IL6, MMP1, MMP8
20autosomal recessive type iv ehlers-danlos syndrome9.9IL6, MMP1, MMP8
21cholera9.9IL6, MMP1, MMP8
22fecal incontinence9.9MMP1, MMP3
23idiopathic corneal edema9.9MMP1, MMP3
24intratubular embryonal carcinoma9.9IL6, MMP1, MMP8
25keratoconus9.9IL6, MMP3
26congenital diaphragmatic hernia9.9
27pythiosis9.9ACHE, NPPA
28carotenemia9.8IL6, MMP1, MMP3
29germ cell and embryonal cancer9.8IL6, MMP1, MMP3
30short bowel syndrome9.8
31synovium cancer9.8IL6, MMP1, MMP3
32bone angioendothelial sarcoma9.8IL6, MMP1, MMP3
33osteonecrosis9.8IL6, MMP1, MMP3
34zika fever9.8MMP1, MMP3
35kashin-beck disease9.8ACHE, MMP1, MMP3
36jejunal atresia9.8
37esophagitis9.8
38oligohydramnios9.8
39autistic disorder9.7IL6, MMP1, MMP3
40myocardial infarction9.7ADD1, IL6, MMP3, NPPA
41neural tube defects9.7
42prune belly syndrome9.7
43cryptorchidism9.7
44colonic atresia9.7
45craniosynostosis9.7
46orofacial cleft9.7
47cloacal exstrophy9.7
48gastric dilatation9.7
49ischemia9.7
50neuronitis9.7

Graphical network of the top 20 diseases related to Gastroschisis:



Diseases related to gastroschisis

Symptoms & Phenotypes for Gastroschisis

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Human phenotypes related to Gastroschisis:

 64
id Description HPO Frequency HPO Source Accession
1 gastroschisis64 HP:0001543
2 intestinal atresia64 HP:0011100
3 abnormality of mesentery morphology64 HP:0100016

MGI Mouse Phenotypes related to Gastroschisis according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053978.3ACHE, ADD1, BMP1, IL6, MMP3, NPPA
2MP:00053765.8ACHE, ADD1, AEBP1, BMP1, IL6, MMP1

Drugs & Therapeutics for Gastroschisis

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Drugs for Gastroschisis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 31)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Metoclopramideapproved, investigationalPhase 3120364-62-54168
Synonyms:
(metaclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
(metoclopramide)4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
1,5-Dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
2-Methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide
2-Methoxy-4-amino-5-chloro-N,N-dimethylaminoethyl)benzamide
2-Methoxy-5-chloroprocainamide
2-methoxy-4-amino-5-chloro-N,N-(dimethylaminoethyl)benzamide
2-methoxy-5-chloroprocainamide
2576-84-3 (di-hydrochloride)
364-62-5
4 Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
4-Amino-5-chloro-2-methoxy-N-(beta-diethylaminoethyl)benzamide
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxybenzamide
4-Amino-5-chloro-N-(2-(diethylamino)ethyl)-o-anisamide
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (Mcp)
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide (metoclopramide)
4-Amino-5-chloro-N-(2-diethylamino-ethyl)-2-methoxy-benzamide(Metoclopramide)
4-amino-5-chloro-2-Methoxy-N-(beta-diethylaminoethyl)benzamide
4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-2-methoxybenzamide
4-amino-5-chloro-N-(2-(Diethylamino)ethyl)-O-anisamide
4-amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide
4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxybenzamide
5-Chloro-2-methoxyprocainamide
54143-57-6 (mono-hydrochloride, mono-hydrate)
7232-21-5 (mono-hydrochloride)
AB00053498
AC1L1HKD
AKOS000280832
ARONIS24307
Apo-Metoclop
BPBio1_000217
BPBio1_001100
BRD-K75641298-001-01-5
BRD-K75641298-003-05-2
BRN 1884366
BSPBio_000197
BSPBio_002027
Benzamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)-2-methoxy- (9CI)
Biomol-NT_000082
C07868
C14H22ClN3O2
CAS-7232-21-5
CHEBI:107736
CHEMBL86
CID4168
CLOPRA-"YELLOW"
Cerucal
Clopra
Clopra-Yellow
Clopromate
D00726
DB01233
DEL
DEL 1267
DivK1c_000069
Duraclamid
EINECS 206-662-9
Elieten
Elieten (TN)
Emetid
Emitasol
Emperal
Eucil
Gastrese
Gastro-Timelets
Gastrobid
Gastromax
Gastronerton
Gastrosil
Gastrotablinen
Gastrotem
HMS2089G16
IDI1_000069
Imperan
KBio1_000069
KBio2_002118
 
KBio2_004686
KBio2_007254
KBio3_001527
KBioGR_001307
KBioSS_002118
L001078
LS-20038
Lopac-M-0763
Lopac0_000762
Maxeran
Maxolon
Meclopran
Metaclopramide
Metaclopromide
Metamide
Methochlopramide
Methoclopramide
Metochlopramide
Metoclol
Metoclopramida
Metoclopramida [INN-Spanish]
Metoclopramide (JP15/INN)
Metoclopramide Hcl
Metoclopramide Hydrochloride
Metoclopramide Intensol
Metoclopramide Monohydrochloride, Monohydrate
Metoclopramide Omega
Metoclopramide [INN:BAN:JAN]
Metoclopramidum
Metoclopramidum [INN-Latin]
Metocobil
Metramid
MolPort-000-883-854
Moriperan
Mygdalon
N-(Diethylaminoethyl)-2-methoxy-4-amino-5-chlorobenzamide
NCGC00015643-01
NCGC00015643-02
NCGC00015643-03
NCGC00015643-08
NCGC00024440-03
NCGC00024440-04
NCI60_003185
NINDS_000069
Neu-Sensamide
Nu-Metoclopramide
Octamide
Parmid
Paspertin
Peraprin
Plasil
Plasil (pharmaceutical)
Pms-Metoclopramide
Pramidin
Pramiel
Pramin
Prestwick0_000209
Prestwick1_000209
Prestwick2_000209
Prestwick3_000209
Primperan
Reclomide
Reglan
Reliveran
SPBio_001740
SPBio_002118
ST024773
Spectrum2_001720
Spectrum3_000504
Spectrum4_000964
Spectrum5_001449
Spectrum_001638
Terperan
Terperan (TN)
UNII-L4YEB44I46
bmse000779
metoclopramide
o-Anisamide, 4-amino-5-chloro-N-(2-(diethylamino)ethyl)- (8CI)
2
DopamineapprovedPhase 3383651-61-6, 62-31-7681
Synonyms:
(3H)-Dopamine
.Beta.-(3,4-Dihydroxyphenyl)ethylamine hydrochloride
.alpha.-(3,4-Dihydroxyphenyl)-.beta.-aminoethane
1,2-Benzenediol, 4-(2-aminoethyl)- (9CI)
1,2-Benzenediol, 4-(2-aminoethyl)-, hydrochloride
1,2-Benzenediol, 4-(2-aminoethyl)-, labeled with tritium
153C5321-5FEE-4B0B-8925-F388F0EEEBD1
2-(3,4-Dihydroxyphenyl)ethylamine
2-(3,4-dihydroxyphenyl)ethylamine
2-benzenediol
3,4-Dihydroxyphenethylamine
3,4-Dihydroxyphenethylamine hydrochloride
3,4-Dihydroxyphenylethylamine
3,4-dihydroxyphenethylamine
3-Hydroxtyramine
3-Hydroxytyramine
3-Hydroxytyramine Hydrobromide
3-Hydroxytyramine hydrochloride
4-(2-Aminoethyl)-1,
4-(2-Aminoethyl)-1,2-benzenediol
4-(2-Aminoethyl)-1,2-bezenediol
4-(2-Aminoethyl)-Pyrocatechol
4-(2-Aminoethyl)benzene-1,2-diol
4-(2-Aminoethyl)catechol
4-(2-Aminoethyl)pyrocatechol
4-(2-Aminoethyl)pyrocatechol hydrochloride
4-(2-aminoethyl)-pyrocatechol
50444-17-2
51-61-6
62-31-7 (HYDROCHLORIDE)
AC1L19S5
AC1Q54AX
AC1Q54AY
AKOS003790978
ASL 279
BIDD:ER0506
BPBio1_001123
BSPBio_001932
Biomol-NT_000001
C03758
CHEBI:18243
CHEMBL59
CID681
D07870
DB00988
Deoxyepinephrine
DivK1c_000780
Dopamin
Dopamina
Dopamina [INN-Spanish]
Dopamine
Dopamine (INN)
Dopamine (USAN)(*hydrochloride*)
Dopamine [INN:BAN]
Dopaminum
Dopaminum [INN-Latin]
Dopastat
Dophamine
Dynatra
EINECS 200-110-0
HSDB 3068
Hydroxytyramin
Hydroxytyramine
IDI1_000780
IP 498
Intropin
Intropin [*hydrochloride*]
KBio1_000780
 
KBio2_001492
KBio2_002388
KBio2_002484
KBio2_004060
KBio2_004956
KBio2_005052
KBio2_006628
KBio2_007524
KBio2_007620
KBio3_001152
KBio3_002867
KBio3_002962
KBioGR_001129
KBioGR_002388
KBioGR_002484
KBioSS_001492
KBioSS_002393
KBioSS_002491
KW-3-060
L-DOPAMINE
L000232
LDP
LS-159
Lopac-H-8502
Lopac0_000586
Medopa (TN)
MolPort-001-641-000
NCGC00015519-01
NCGC00015519-08
NCGC00096050-01
NCGC00096050-02
NCGC00096050-03
NCGC00096050-04
NCGC00096050-05
NINDS_000780
NSC 173182
NSC169105
NSC173182
Oprea1_088821
Oxytyramine
Pyrocatechol, 4-(2-aminoethyl)- (8CI)
Pyrocatechol, 4-(2-aminoethyl)-, hydrochloride
Revimine
Revivan
SPBio_001205
SPECTRUM1505155
ST048774
STK301601
Spectrum2_001023
Spectrum3_000406
Spectrum4_000525
Spectrum5_000945
Spectrum_001012
UNII-VTD58H1Z2X
UPCMLD0ENAT5885989:001
a-(3,4-Dihydroxyphenyl)-b-aminoethane
alpha-(3,4-Dihydroxyphenyl)-beta-aminoethane
cMAP_000036
cMAP_000065
dopamine
hydroxytyramine
intropin
m-Hydroxytyramine hydrochloride
nchembio.105-comp9
nchembio.107-comp4
nchembio.284-comp1
nchembio.78-comp16
nchembio.89-comp3
nchembio705-8
nchembio801-comp8
3Peripheral Nervous System AgentsPhase 323689
4Neurotransmitter AgentsPhase 318340
5AntiemeticsPhase 34022
6Gastrointestinal AgentsPhase 3, Phase 1, Phase 28402
7Dopamine D2 Receptor AntagonistsPhase 3333
8Dopamine AgentsPhase 33836
9Autonomic AgentsPhase 310150
10Dopamine AntagonistsPhase 31093
11Pharmaceutical SolutionsPhase 28192
12Soybean oil, phospholipid emulsionPhase 276
13Protective AgentsPhase 27443
14Parenteral Nutrition SolutionsPhase 2160
15AntioxidantsPhase 23050
16Fat Emulsions, IntravenousPhase 297
17
BilirubinPhase 2116635-65-45280352
Synonyms:
(4Z,15Z)-Bilirubin IXa
(Z,Z)-Bilirubin IXa
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionate
1,10,19,22,23,24-Hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-Biline-8,12-dipropionic acid
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoate
2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-Biline-8,12-dipropanoic acid
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoate
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-((3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-2-yl)methyl)-4-methyl-5-((4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl)-1H-pyrrol-3-yl)propanoic acid
 
3-(2-((3-(2-Carboxyethyl)-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl)methyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-1,5-dihydro-2H-pyrrol-2-ylidene
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoate
3-[2-[[3-(2-Carboxyethyl)-5-[(Z)-(3-ethenyl-4-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-2-yl]methyl]-5-[(Z)-(4-ethenyl-3-methyl-5-oxo-pyrrol-2-ylidene)methyl]-4-methyl-1H-pyrrol-3-yl]propanoic acid
Bilirubin
Bilirubin IX-alpha
Cholerythrin
Hematoidin
18Liver ExtractsPhase 24067
19Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 1, Phase 213168
20IncretinsPhase 1, Phase 21579
21HormonesPhase 1, Phase 214415
22Hormone AntagonistsPhase 1, Phase 213180
23glucagonPhase 1, Phase 2478
24Glucagon-Like Peptide 1Phase 1, Phase 2715
25Omega 3 Fatty AcidNutraceuticalPhase 21018
26Soy BeanNutraceuticalPhase 2554
27Micronutrients6001
28Vitamins5282
29Trace Elements6001
30BifidobacteriumNutraceutical247
31lysineNutraceutical98

Interventional clinical trials:

(show all 17)
idNameStatusNCT IDPhase
1Trial of AMNIOECHANGE in Gastroschisis Affected FoetusesUnknown statusNCT00127946Phase 3
2Metoclopramide Pilot TrialRecruitingNCT02098915Phase 3
3Randomized Clinical Trial of Early Delivery in Fetal Gastroschisis vs. Routine CareActive, not recruitingNCT01884324Phase 2, Phase 3
4Evaluating the Use of a Silastic Spring-Loaded Silo for Infants With GastroschisisCompletedNCT00539292Phase 2
5Compassionate Use of Omegaven in ChildrenRecruitingNCT02370251Phase 2
6Safety and Dosing Study of Glucagon-like Peptide 2 (GLP-2) in Infants and Children With Intestinal FailureTerminatedNCT01573286Phase 1, Phase 2
7Sutureless vs Sutured Gastroschisis ClosureUnknown statusNCT01094587
8Music Therapy: An Adjunct To Gastroschisis Infants' CareUnknown statusNCT01469208
9Probiotics in Infants With GastroschisisUnknown statusNCT01316510
10Elemental Formula in Neonates Post Small Bowel Resection: Improved Weaning From Total Parenteral Nutrition?Unknown statusNCT01891279
11PREMAPIV : Intravesical Pressure Variation at Different Bladder Instillation Volumes in Newborn ChildrenCompletedNCT01296724
12Determination of Lysine Requirement in the Parenterally Fed NeonateCompletedNCT00779753
13Silo Versus Primary Closure for GastroschisisRecruitingNCT01506531
14Clinical and Biological Outcomes of Human Milk and Formula Intake After Gastroschisis RepairRecruitingNCT02575846
15Gastroschisis Outcomes of Delivery (GOOD) StudyNot yet recruitingNCT02774746
16Bedside Silo Versus Operative Closure for GastroschisisTerminatedNCT00404690
17Prevention of Parenteral Nutrition-Associated Cholestasis With Cyclic Parenteral Nutrition in InfantsTerminatedNCT01062815

Search NIH Clinical Center for Gastroschisis


Cochrane evidence based reviews: gastroschisis

Genetic Tests for Gastroschisis

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Anatomical Context for Gastroschisis

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MalaCards organs/tissues related to Gastroschisis:

36
Skin, Liver, Small intestine, Colon, Heart, Smooth muscle, Testis

Publications for Gastroschisis

About this section

Articles related to Gastroschisis:

(show top 50)    (show all 722)
idTitleAuthorsYear
1
Newborn with Gastroschisis associated with Limb Anomalies. (28083494)
2017
2
Chylous Ascites in a Newborn with Gastroschisis. Case Report. (28083502)
2017
3
Maternal Stressors and Social Support and Risks of Delivering Babies With Gastroschisis or Hypospadias. (28505275)
2017
4
Not gastroschisis or omphalocele or anything in between: a novel congenital abdominal wall defect. (28271155)
2017
5
Transamniotic stem cell therapy (TRASCET) in a leporine model of gastroschisis. (27836365)
2017
6
Umbilical hernia following gastroschisis closure: a common event? (27344584)
2016
7
Outcome of isolated gastroschisis; an international study, systematic review and meta-analysis. (27825040)
2016
8
Neurodevelopment and Health-Related Quality of Life in Infants Born with Gastroschisis: A 6-Year Retrospective French Study. (27931048)
2016
9
Relationship between neonatal gastroschisis and maternal body mass index in a United Kingdom population. (28088673)
2016
10
Spatial variability of gastroschisis in Canada, 2006-2011: An exploratory analysis. (27348112)
2016
11
Management of gastroschisis. (26974976)
2016
12
Oligohydramnios and growth restriction do not portend worse prognosis in gastroschisis pregnancies. (26932657)
2016
13
Fetal gastroschisis: antepartum fetal heart rate analysis by computerized cardiotocography. (27180816)
2016
14
Gastroschisis: A Review of Management and Outcomes. (27640608)
2016
15
Gastroschisis: mortality risks with each additional week of expectant management. (27596619)
2016
16
Improved outcomes for inborn babies with uncomplicated gastroschisis. (28017414)
2016
17
Gastroschisis: Bellwether for neonatal surgery capacity in low resource settings? (27032610)
2016
18
Variability of outcome reporting in Hirschsprung's Disease and gastroschisis: a systematic review. (27941923)
2016
19
Assessing quality of life in pediatric gastroschisis patients using the Pediatric Quality of Life Inventory survey: An institutional study. (26932251)
2016
20
Gene variants as risk factors for gastroschisis. (27616475)
2016
21
Quality of life in patients with gastroschisis is comparable with the general population: A questionnaire survey. (27982137)
2016
22
Gastroschisis: epidemiology and mode of delivery, 2005-2013. (27026476)
2016
23
Gastroschisis with gastric perforation and jejunal stenosis. A rare association of anomalies. (26996209)
2016
24
Closed gastroschisis, vanishing midgut and extreme short bowel syndrome: Case report and review of the literature. (27867410)
2016
25
Geospatial clustering of gastroschisis in Poland: Data from the Polish Registry of Congenital Malformations (PRCM). (26988884)
2016
26
Gastroschisis in Uganda: Opportunities for improved survival. (27516176)
2016
27
Is there a relationship between hospital volume and patient outcomes in gastroschisis repair? (27139881)
2016
28
Management and outcome challenges in newborns with gastroschisis: A 6-year retrospective French study. (27892784)
2016
29
Gastroschisis outcomes in North America: a comparison of Canada and the United States. (27004440)
2016
30
Gastroschisis and maternal intake of phytoestrogens. (27232448)
2016
31
Mortality-related factors in gastroschisis - a Jamaican perspective. (27842958)
2016
32
The Influence of Infectious Complications in Gastroschisis on Costs and Length of Stay. (27240097)
2016
33
The epidemiology, prevalence and hospital outcomes of infants with gastroschisis. (27388940)
2016
34
Intra-Amniotic Hemorrhage Imitating Gastroschisis: A Case Report and Review of the Literature. (27760979)
2016
35
Gastroschisis in a fetus with a congenital neuroblastoma: Association or coincidence? (26875914)
2016
36
Gastroschisis with Concomitant Jejuno-Ileal Atresia Complicated by Jejunal Perforation. (27123409)
2016
37
Folic acid fortification and prevalences of neural tube defects, orofacial clefts, and gastroschisis in California, 1989 to 2010. (27191125)
2016
38
Response to Letter to the Editor Regarding "Probiotic Administration in Infants with Gastroschisis: a Pilot Randomized Placebo-controlled Trial". (27579695)
2016
39
Maternal Antibodies to Herpes Virus Antigens and Risk of Gastroschisis in Offspring. (27856447)
2016
40
Flap versus fascial closure for gastroschisis: a systematic review and meta-analysis. (26970850)
2016
41
Babies born with gastroschisis and followed up to the age of six years faced long-term morbidity and impairments. (26910581)
2016
42
What prenatal ultrasound features are predictable of complex or vanishing gastroschisis? A retrospective study. (27981591)
2016
43
Heightened Immune Activation in Fetuses with Gastroschisis May Be Blocked by Targeting IL-5. (27183609)
2016
44
Accuracy of antenatal ultrasound signs in predicting the risk for bowel atresia in patients with gastroschisis. (27280540)
2016
45
Development of a core outcome set for use in determining the overall success of gastroschisis treatment. (27465672)
2016
46
Measuring self-reported quality of life in 8- to 11-year-old children born with gastroschisis: Is the KIDSCREEN questionnaire acceptable? (26931186)
2016
47
Outcome reporting in randomized controlled trials and systematic reviews of gastroschisis treatment: a systematic review. (27312236)
2016
48
Effect of gestational age at birth on neonatal outcomes in gastroschisis. (26932253)
2016
49
Closed Gastroschisis with Vanished Small Bowel and Jejunal Atresia. (27896173)
2016
50
Gastroschisis Complicated by Septo-Optic Dysplasia: Two Distinct Anomalies with a Common Origin. (26929863)
2016

Variations for Gastroschisis

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Expression for genes affiliated with Gastroschisis

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Search GEO for disease gene expression data for Gastroschisis.

Pathways for genes affiliated with Gastroschisis

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Pathways related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 15)
idSuper pathwaysScoreTop Affiliating Genes
19.7IL6, TGFB3
29.7IL6, TGFB3
39.7IL6, TGFB3
49.5IL6, MMP1
59.5IL6, MMP1
69.3BMP1, IL6, TGFB3
79.3MMP1, MMP3
89.1IL6, MMP1, TGFB3
9
Show member pathways
9.0IL6, MMP1, MMP3
109.0IL6, MMP1, MMP3
11
Show member pathways
9.0IL6, MMP1, MMP3
128.5IL6, MMP1, MMP3, TGFB3
13
Show member pathways
8.5MMP1, MMP3, MMP8
14
Show member pathways
7.8BMP1, MMP1, MMP3, MMP8, TGFB3
15
Show member pathways
7.4BMP1, IL6, MMP1, MMP3, MMP8, TGFB3

GO Terms for genes affiliated with Gastroschisis

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Cellular components related to Gastroschisis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular matrixGO:00310128.6AEBP1, MMP1, MMP3, MMP8, TGFB3
2proteinaceous extracellular matrixGO:00055788.2BMP1, MMP1, MMP3, MMP8
3extracellular spaceGO:00056157.3ACHE, AEBP1, BMP1, IL6, MMP3, MMP8
4extracellular regionGO:00055766.8ACHE, AEBP1, BMP1, IL6, MMP1, MMP3

Biological processes related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 7)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of DNA replicationGO:004574010.4IL6, TGFB3
2positive regulation of protein secretionGO:005071410.2ACHE, TGFB3
3positive regulation of protein oligomerizationGO:003246110.0MMP1, MMP3
4cellular protein metabolic processGO:00442679.7IL6, MMP1, NPPA
5collagen catabolic processGO:00305749.2MMP1, MMP3, MMP8
6extracellular matrix disassemblyGO:00226178.9BMP1, MMP1, MMP3, MMP8
7proteolysisGO:00065087.9AEBP1, BMP1, MMP1, MMP3, MMP8

Molecular functions related to Gastroschisis according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1cytokine activityGO:000512510.1BMP1, IL6, TGFB3
2growth factor activityGO:000808310.1BMP1, IL6, TGFB3
3calcium ion bindingGO:00055098.9BMP1, MMP1, MMP3, MMP8
4metalloendopeptidase activityGO:00042228.9BMP1, MMP1, MMP3, MMP8
5metallopeptidase activityGO:00082378.9BMP1, MMP1, MMP3, MMP8
6peptidase activityGO:00082338.9BMP1, MMP1, MMP3, MMP8
7serine-type endopeptidase activityGO:00042528.9BMP1, MMP1, MMP3, MMP8
8zinc ion bindingGO:00082707.9AEBP1, BMP1, MMP1, MMP3, MMP8

Sources for Gastroschisis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet