MCID: GNC003
MIFTS: 34

Geniculate Herpes Zoster malady

Categories: Rare diseases, Neuronal diseases, Infectious diseases

Aliases & Classifications for Geniculate Herpes Zoster

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Aliases & Descriptions for Geniculate Herpes Zoster:

Name: Geniculate Herpes Zoster 11 13
Herpes Zoster Oticus 11 46 47 37 66
Nervus Intermedius Neuralgia 11 46 66
Facial Nerve Palsy Due to Herpes Zoster Infection 46 52
Facial Nerve Paralysis Due to Vzv 46 52
Facial Nerve Palsy Due to Vzv 46 52
Ramsay Hunt Syndrome Type 2 11 46
Geniculate Neuralgia 11 46
 
Ramsay Hunt Syndrome 46 52
Herpetic Geniculate Ganglionitis 11
Ramsay Hunt Syndrome Type Ii 11
Herpes Zoster Auricularis 11
Ramsay Hunt Syndrome Ii 47
Myoclonus and Ataxia 66
Hunt's Syndrome 46
Hunt Syndrome 46

Characteristics:

Orphanet epidemiological data:

52
facial nerve palsy due to herpes zoster infection:
Inheritance: Not applicable; Prevalence: 1-9/100000 (United States); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:9210
ICD1028 B02.21
ICD9CM30 053.11
MeSH37 D016697
NCIt43 C84763
Orphanet52 ORPHA3020
ICD10 via Orphanet29 B02.2+, G53.0*

Summaries for Geniculate Herpes Zoster

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NIH Rare Diseases:46 Herpes zoster oticus is a common complication of shingles, an infection caused by the varicella-zoster virus (which is the virus that also causes chickenpox). shingles occurs in people who have had chickenpox and in whom the varicella-zoster virus becomes active again. herpes zoster oticus is caused by the spread of the virus to facial nerves and can cause intense ear pain; a rash around the ear, mouth, face, neck, and scalp; and paralysis of the face. other symptoms may include hearing loss, vertigo (feeling that the room is spinning), tinnitus (hearing abnormal sounds), nausea, vomiting, loss of taste in the tongue, and dry mouth and eyes. some cases of herpes zoster oticus do not require treatment, but when treatment is needed, pain medications, antiviral drugs or corticosteroids may be prescribed. vertigo is sometimes treated with medication as well. the prognosis of herpes zoster oticus is typically good, but in some cases hearing loss or facial paralysis may be permanent.  last updated: 8/19/2016

MalaCards based summary: Geniculate Herpes Zoster, also known as herpes zoster oticus, is related to tolosa-hunt syndrome and myoclonic cerebellar dyssynergia, and has symptoms including vesicular rash of the ear or mouth, tinnitus and vertigo. An important gene associated with Geniculate Herpes Zoster is MT-TC (Mitochondrially Encoded TRNA Cysteine), and among its related pathways is Primary immunodeficiency. Affiliated tissues include facial nerve, tongue and eye.

Disease Ontology:11 A viral infectious disease that results in inflammation located in facial nerve, which leads to paralysis of one side of the face, has material basis in human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. the infection has symptom vesicular rash of the ear or mouth, has symptom tinnitus, has symptom vertigo, has symptom otalgia, and has symptom headache.

NINDS:47 Some cases of herpes zoster oticus do not require treatment. When treatment is needed, medications such as antiviral drugs or corticosteroids may be prescribed. Vertigo may be treated with the drug diazepam

Wikipedia:69 Ramsay Hunt syndrome type 2, also known as herpes zoster oticus, is a disorder that is caused by the... more...

Related Diseases for Geniculate Herpes Zoster

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Diseases related to Geniculate Herpes Zoster via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 192)
idRelated DiseaseScoreTop Affiliating Genes
1tolosa-hunt syndrome12.4
2myoclonic cerebellar dyssynergia11.1
3rickettsialpox10.4CD40LG, KANTR
4facial nerve neoplasm10.4CD40LG, KANTR
5waldeyer's ring cancer10.4CD40LG, HP
6brachial plexus neuropathy10.4CD40LG, KANTR
7rocky mountain spotted fever10.4CD40LG, KANTR
8urinary schistosomiasis10.4CD40LG, KANTR
9american histoplasmosis10.4CD40LG, KANTR
10lynch syndrome10.4CD40LG, KANTR
11bladder squamous papilloma10.4HP, KANTR
12geniculate ganglionitis10.4
13calcific tendinitis10.3CD40LG, CD79A
14medullary sponge kidney10.3CD40LG, CD79A
15variola major10.3CD40LG, CD79A
16mu chain disease10.3CD40LG, CD79A
17calcium metabolism disease10.3CD40LG, CD79A
18retinal cancer10.3CD40LG, CD79A
19focal embolic glomerulonephritis10.3CD40LG, CD79A
20membranous glomerulonephritis10.3CD40LG, CD79A
21endometrial stromal nodule10.3CD40LG, CD79A
22chronic cystitis10.3CD40LG, CD79A
23intestinal pseudo-obstruction10.3CD40LG, KANTR
24hemolytic-uremic syndrome10.3CD40LG, CD79A
25partial motor epilepsy10.3CD40LG, CD79A
26benign meningioma10.3CD40LG, CD79A
27parasitic helminthiasis infectious disease10.3CD40LG, CD79A
28occlusion of gallbladder10.3CD40LG, CD79A
29viral meningitis10.3CD40LG, CD79A
30substance-induced psychosis10.3CD40LG, CD79A
31gamma heavy chain disease10.3CD40LG, CD79A
32regional ureteric cancer10.3CD40LG, CD79A
33arteriosclerosis10.3CD40LG, CD79A
34bacterial conjunctivitis10.3CD40LG, CD79A
35deep keratitis10.3CD40LG, CD79A
36monoclonal paraproteinemia10.3CD40LG, CD79A
37cockayne syndrome10.3CD40LG, CD79A
38juvenile type testicular granulosa cell tumor10.3CD40LG, CD79A
39testicular brenner tumor10.3CD40LG, CD79A
40oculo cerebro osseous syndrome10.3CD40LG, CD79A
41diabetic angiopathy10.3CD40LG, CD79A
42fallopian tube leiomyosarcoma10.3CD40LG, CD79A
43adult extraosseous chondrosarcoma10.3CD40LG, CD79A
44brucella abortus brucellosis10.3CD40LG, CD79A
45ganglioneuroblastoma10.3CD40LG, CD79A
46small intestinal vasoactive intestinal peptide producing tumor10.3CD40LG, CD79A
47oesophagostomiasis10.3CD40LG, KANTR
48b cell linker protein deficiency10.3CD40LG, CD79A
49post-traumatic stress disorder10.3CD40LG, CD79A
50malignant hypertension10.3CD40LG, HP

Comorbidity relations with Geniculate Herpes Zoster via Phenotypic Disease Network (PDN):


Facial Paralysis

Graphical network of the top 20 diseases related to Geniculate Herpes Zoster:



Diseases related to geniculate herpes zoster

Symptoms for Geniculate Herpes Zoster

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Symptoms:

 11
  • vesicular rash of the ear or mouth
  • tinnitus
  • vertigo
  • otalgia
  • headache

UMLS symptoms related to Geniculate Herpes Zoster:


earache, neuralgia, pain of ear structure, pain

Drugs & Therapeutics for Geniculate Herpes Zoster

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Transcranial Magnetic Stimulation for Facial PainRecruitingNCT02633306Phase 1

Search NIH Clinical Center for Geniculate Herpes Zoster


Cochrane evidence based reviews: herpes zoster oticus

Genetic Tests for Geniculate Herpes Zoster

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Anatomical Context for Geniculate Herpes Zoster

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MalaCards organs/tissues related to Geniculate Herpes Zoster:

34
Tongue, Eye

FMA organs/tissues related to Geniculate Herpes Zoster:

17
Facial nerve

Animal Models for Geniculate Herpes Zoster or affiliated genes

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Publications for Geniculate Herpes Zoster

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Variations for Geniculate Herpes Zoster

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Expression for genes affiliated with Geniculate Herpes Zoster

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Search GEO for disease gene expression data for Geniculate Herpes Zoster.

Pathways for genes affiliated with Geniculate Herpes Zoster

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Pathways related to Geniculate Herpes Zoster according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4CD40LG, CD79A

GO Terms for genes affiliated with Geniculate Herpes Zoster

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Biological processes related to Geniculate Herpes Zoster according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1B cell proliferationGO:00421009.4CD40LG, CD79A
2B cell differentiationGO:00301839.4CD40LG, CD79A
3acute-phase responseGO:00069539.0HP, SERPINA1

Sources for Geniculate Herpes Zoster

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet