MCID: GNC003
MIFTS: 32

Geniculate Herpes Zoster malady

Categories: Rare diseases, Neuronal diseases, Infectious diseases

Aliases & Classifications for Geniculate Herpes Zoster

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Aliases & Descriptions for Geniculate Herpes Zoster:

Name: Geniculate Herpes Zoster 11 13
Herpes Zoster Oticus 11 48 49 39 68
Nervus Intermedius Neuralgia 11 48 68
Facial Nerve Palsy Due to Herpes Zoster Infection 48 54
Facial Nerve Paralysis Due to Vzv 48 54
Facial Nerve Palsy Due to Vzv 48 54
Geniculate Neuralgia 11 48
 
Ramsay Hunt Syndrome 48 54
Herpetic Geniculate Ganglionitis 11
Ramsay Hunt Syndrome Type Ii 11
Ramsay Hunt Syndrome Type 2 11
Herpes Zoster Auricularis 11
Ramsay Hunt Syndrome Ii 49
Myoclonus and Ataxia 68

Characteristics:

Orphanet epidemiological data:

54
facial nerve palsy due to herpes zoster infection:
Inheritance: Not applicable; Prevalence: 1-9/100000 (United States); Age of onset: All ages; Age of death: normal life expectancy

Classifications:



External Ids:

Disease Ontology11 DOID:9210
ICD1030 B02.21
ICD9CM32 053.11
MeSH39 D016697
NCIt45 C84763
Orphanet54 ORPHA3020
ICD10 via Orphanet31 B02.2+, G53.0*

Summaries for Geniculate Herpes Zoster

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NIH Rare Diseases:48 Herpes zoster oticus is a common complication of shingles, an infection caused by the varicella-zoster virus (which is the virus that also causes chickenpox). shingles occurs in people who have had chickenpox and in whom the varicella-zoster virus becomes active again. herpes zoster oticus is caused by the spread of the virus to facial nerves and can cause intense ear pain; a rash around the ear, mouth, face, neck, and scalp; and paralysis of the face. other symptoms may include hearing loss, vertigo (feeling that the room is spinning), tinnitus (hearing abnormal sounds), nausea, vomiting, loss of taste in the tongue, and dry mouth and eyes. some cases of herpes zoster oticus do not require treatment, but when treatment is needed, pain medications, antiviral drugs or corticosteroids may be prescribed. vertigo is sometimes treated with medication as well. the prognosis of herpes zoster oticus is typically good, but in some cases hearing loss or facial paralysis may be permanent.  last updated: 8/19/2016

MalaCards based summary: Geniculate Herpes Zoster, also known as herpes zoster oticus, is related to ramsay hunt syndrome i and geniculate ganglionitis, and has symptoms including earache, neuralgia and vesicular rash of the ear or mouth. An important gene associated with Geniculate Herpes Zoster is MT-TC (Mitochondrially Encoded TRNA Cysteine), and among its related pathways is Primary immunodeficiency. Affiliated tissues include facial nerve, tongue and eye.

Disease Ontology:11 A viral infectious disease that results in inflammation located in facial nerve, which leads to paralysis of one side of the face, has material basis in Human herpesvirus 3, which reactivates after appearing as chickenpox in childhood. The infection has symptom vesicular rash of the ear or mouth, has symptom tinnitus, has symptom vertigo, has symptom otalgia, and has symptom headache.

NINDS:49 Herpes zoster oticus, also called Ramsay Hunt Syndrome or Ramsay Hunt Syndrome type II, is a common complication of shingles. Shingles is an infection caused by the varicella-zoster virus, which is the virus that causes chickenpox. Shingles occurs in people who have had chickenpox and represents a reactivation of the dormant varicella-zoster virus. Herpes zoster oticus, which is caused by the spread of the varicella-zoster virus to facial nerves, is characterized by intense ear pain, a rash around the ear, mouth, face, neck, and scalp, and paralysis of facial nerves. Other symptoms may include hearing loss, vertigo (abnormal sensation of movement), and tinnitus (abnormal sounds). Taste loss in the tongue and dry mouth and eyes may also occur.

Wikipedia:71 Ramsay Hunt syndrome type 2, also known as herpes zoster oticus, is a disorder that is caused by the... more...

Related Diseases for Geniculate Herpes Zoster

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Diseases related to Geniculate Herpes Zoster via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 173)
idRelated DiseaseScoreTop Affiliating Genes
1ramsay hunt syndrome i12.1
2geniculate ganglionitis11.1
3oculoauricular syndrome10.3CD40LG, MT-TC
4tonsillar fossa cancer10.2CD40LG, HP
5adrenal gland ganglioneuroblastoma10.2CD40LG, TNFRSF10A
6facial nerve neoplasm10.2CD40LG, KANTR
7spastic ataxia 7, autosomal dominant10.2CD40LG, KANTR
8spotted fever10.2CD40LG, KANTR
9anal canal adenocarcinoma10.2CD40LG, KANTR
10oropharyngeal anthrax10.2CD40LG, KANTR
11human immunodeficiency virus infectious disease10.2CD40LG, TNFRSF10A
12mechanical entropion10.2HP, KANTR
13benign paroxysmal positional nystagmus10.2CD40LG, KANTR
14cardiovascular cancer10.2CD40LG, KANTR
15alcoholic neuropathy10.2CD40LG, CD79A
16camptodactyly vertebral fusion10.2CD40LG, CD79A
17spinal polio10.2CD40LG, CD79A
18rabies10.2CD40LG, CD79A
19unilateral retinoblastoma10.2CD40LG, CD79A
20mesangial proliferative glomerulonephritis10.2CD40LG, CD79A
21delta chain disease10.2CD40LG, CD79A
22discitis10.2CD40LG, CD79A
23trichostrongyloidiasis10.2CD40LG, CD79A
24colloid adenoma10.2CD40LG, CD79A
25heart septal defect10.2CD40LG, CD79A
26mild pre-eclampsia10.2CD40LG, CD79A
27retinal microaneurysm10.2CD40LG, CD79A
28pediatric meningioma10.2CD40LG, CD79A
29tonsil cancer10.2CD40LG, CD79A
30indomethacin antenatal infection10.2CD40LG, CD79A
31postcricoid region cancer10.2CD40LG, CD79A
32beach ear10.2CD40LG, CD79A
33acute kidney tubular necrosis10.2CD40LG, CD79A
34atheroembolism of kidney10.2CD40LG, CD79A
35hidrocystoma10.2CD40LG, KANTR
36partial sensory epilepsy10.2CD40LG, CD79A
37ritscher-schinzel syndrome 110.2CD40LG, CD79A
38diabetic angiopathy10.2CD40LG, CD79A
39endocarditis10.2CD40LG, CD79A
40muscular dystrophy10.2CD40LG, CD79A
41dumping syndrome10.2CD40LG, CD79A
42striatonigral degeneration10.2CD40LG, CD79A
43ciliary body spindle cell melanoma10.2CD40LG, CD79A
44purulent endophthalmitis10.2CD40LG, CD79A
45generalized dystonia10.2CD40LG, KANTR
46mu chain disease10.2CD40LG, CD79A
47generalized atherosclerosis10.2CD40LG, CD79A
48bursitis10.2CD40LG, CD79A
49syphilis10.2CD40LG, CD79A
50mental retardation, autosomal dominant 1910.2CD40LG, CD79A

Comorbidity relations with Geniculate Herpes Zoster via Phenotypic Disease Network (PDN):


Facial Paralysis

Graphical network of the top 20 diseases related to Geniculate Herpes Zoster:



Diseases related to geniculate herpes zoster

Symptoms & Phenotypes for Geniculate Herpes Zoster

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Symptoms:

 11 (show all 5)
  • vesicular rash of the ear or mouth
  • tinnitus
  • vertigo
  • otalgia
  • headache

UMLS symptoms related to Geniculate Herpes Zoster:


earache, neuralgia

Drugs & Therapeutics for Geniculate Herpes Zoster

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Interventional clinical trials:

idNameStatusNCT IDPhase
1Transcranial Magnetic Stimulation for Facial PainRecruitingNCT02633306Phase 1

Search NIH Clinical Center for Geniculate Herpes Zoster


Cochrane evidence based reviews: herpes zoster oticus

Genetic Tests for Geniculate Herpes Zoster

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Anatomical Context for Geniculate Herpes Zoster

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MalaCards organs/tissues related to Geniculate Herpes Zoster:

36
Tongue, Eye

FMA organs/tissues related to Geniculate Herpes Zoster:

17
Facial nerve

Publications for Geniculate Herpes Zoster

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Variations for Geniculate Herpes Zoster

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Expression for genes affiliated with Geniculate Herpes Zoster

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Search GEO for disease gene expression data for Geniculate Herpes Zoster.

Pathways for genes affiliated with Geniculate Herpes Zoster

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Pathways related to Geniculate Herpes Zoster according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.4CD40LG, CD79A

GO Terms for genes affiliated with Geniculate Herpes Zoster

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Biological processes related to Geniculate Herpes Zoster according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1acute-phase responseGO:00069539.6HP, SERPINA1
2B cell proliferationGO:00421009.4CD40LG, CD79A

Sources for Geniculate Herpes Zoster

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet