Geographic Tongue disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

NIH Rare Diseases:⁴⁸ Geographic tongue is a condition that causes chronic and recurrent lesions on the tongue that resemble psoriasis of the skin. it is characterized by pink to red, slightly depressed lesions with irregular, elevated, white or yellow borders. the lesions may also occur in the mucosa of the mouth and labia; this condition is called "areata migrans" because these lesions typically disappear from one area and show up in another. the tongue is normally covered with tiny, pinkish-white bumps (papillae), which are actually short, fine, hair-like projections. with geographic tongue, patches on the surface of the tongue are missing papillae and appear as smooth, red "islands," often with slightly raised borders. these patches (lesions) give the tongue a map-like, or geographic, appearance. in most cases there are no symptoms but sometimes it is painful when inflamed. the cause of this condition is unknown. many researchers think it is linked with psoriasis, but more research is needed to better understand the connection. also, hereditary and environmental factors may be involved. the condition is benign and localized, generally requiring no treatment except reassurance. if painful, it may be treated with steroid gels or antihistamine mouth rinses. last updated: 4/14/2016

MalaCards based summary: Geographic Tongue, also known as glossitis, benign migratory, is related to lyme disease and fissured tongue, and has symptoms including exanthema, glossalgia and glossalgia. An important gene associated with Geographic Tongue is IL36RN (Interleukin 36 Receptor Antagonist), and among its related pathways are Translocation of ZAP-70 to Immunological synapse and MHC class II antigen presentation. Affiliated tissues include tongue and skin, and related mouse phenotypes are Increased shRNA abundance (Z-score > 2) and neoplasm.

Disease Ontology:¹¹ An atrophic glossitis that is characterized as an inflammatory condition of the mucous membrane of the tongue, usually on the dorsal surface.

Wikipedia:⁷¹ Geographic tongue, also known by several other terms,[note 1] is an inflammatory condition of the mucous... more...

Related Diseases for Geographic Tongue

Sources:
²⁰GeneAnalytics, ²¹GeneCards
See all MalaCards sources

Diseases related to Geographic Tongue via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 79)

id	Related Disease	Score	Top Affiliating Genes
1	lyme disease	11.5
2	fissured tongue	11.4
3	solid pseudopapillary carcinoma of pancreas	10.3	HLA-A, HLA-B
4	apple allergy	10.3	HLA-DQB1, HLA-DRB1
5	hodgkin's paragranuloma	10.3	HLA-DQB1, HLA-DQB2
6	hemoglobin d disease	10.3	HLA-DQB1, HLA-DRB1
7	myopathy, congenital nonprogressive, with moebius sequence and robin sequence	10.3	HLA-A, HLA-B
8	ragweed sensitivity	10.2	HLA-DQB1, HLA-DQB2, HLA-DRB1
9	sacral nerve root cysts	10.2	HLA-A, HLA-B, HLA-DRB1
10	bilateral parasagittal parieto-occipital polymicrogyria	10.2	HLA-DQB1, HLA-DRB1
11	hernia of ovary and fallopian tube	10.2	HLA-A, HLA-B, HLA-DRB1
12	immune deficiency, familial variable	10.2	HLA-B, HLA-DQB1, HLA-DRB1
13	nystagmus, congenital motor, autosomal recessive	10.2	HLA-A, HLA-B, HLA-DRB1
14	aseptic meningitis	10.2	HLA-A, HLA-B, HLA-DRB1
15	cervical adenoid basal carcinoma	10.2	HLA-B, HLA-DQB1, HLA-DRB1
16	epididymo-orchitis	10.2	HLA-A, HLA-B, HLA-C
17	acanthoma	10.2	HLA-A, HLA-B, HLA-DRB1
18	lin-gettig syndrome	10.2	HLA-DQB1, HLA-DRB1
19	colorectal cancer, hereditary nonpolyposis, type 6	10.2	HLA-A, HLA-B, HLA-C
20	b-cell lymphomas	10.2	HLA-A, HLA-DQB1, HLA-DRB1
21	cryptococcosis	10.2	HLA-B, HLA-DQB1, HLA-DRB1
22	pyridoxine-responsive sideroblastic anemia	10.2	CD79A, TGM2
23	rete testis adenocarcinoma	10.2	AKTIP, HLA-A, HLA-DQB1, IL36RN
24	patau syndrome	10.2	HLA-A, HLA-DRB1, TNFRSF10B
25	orbital osteomyelitis	10.2	HLA-A, HLA-B, HLA-C
26	clostridium difficile colitis	10.2	CD79A, HLA-DQB1, HLA-DRB1
27	squamous cell papilloma of skin	10.2	AKTIP, CD79A, HLA-A
28	pemphigus vulgaris, familial	10.2	HLA-A, HLA-B, HLA-DRB1
29	acute cholangitis	10.2	HLA-B, HLA-C, HLA-DRB1
30	mirizzi syndrome	10.2	HLA-B, HLA-DRB1
31	acrodermatitis	10.2
32	lymphangiectasia, intestinal	10.2	CD79A, HLA-DQB1, HLA-DRB1
33	choreatic disease	10.2	CD79A, HLA-DQB1, HLA-DRB1
34	pseudohypoparathyroidism	10.2	CD79A, HLA-C, HLA-DRB1
35	cutaneous solitary mastocytoma	10.1	CD79A, TGM2
36	parasitic helminthiasis infectious disease	10.1	HLA-A, HLA-B, HLA-DQB1, HLA-DRB1
37	neonatal antiphospholipid syndrome	10.1	HLA-DQB1, HLA-DRB1, VEGFA
38	good syndrome	10.1	CD79A, HLA-DQB1, TGM2
39	amyotrophic lateral sclerosis type 10	10.1	CD79A, TGM2
40	midline interhemispheric variant of holoprosencephaly	10.1	HLA-DQB1, HLA-DRB1
41	acrodermatitis chronica atrophicans	10.1
42	monocytic leukemia	10.1	CD79A, HLA-DQB1, HLA-DRB1
43	hepatitis	10.1	HLA-A, HLA-B, HLA-C, HLA-DRB1
44	disease of mental health	10.1	CD79A, HLA-B, HLA-DRB1
45	autosomal recessive congenital methemoglobinemia	10.1	EPHX1, HLA-A, HLA-B, HLA-C
46	psoriasis susceptibility 1	10.1	EPHX1, HLA-A, HLA-B, HLA-C
47	barbiturate abuse	10.1	CD79A, HLA-DQB1, TGM2
48	partial sensory epilepsy	10.1	BRD4, CD79A
49	inflammatory bowel disease 3	10.0	CD79A, HLA-A, HLA-DQB1, TGM2
50	learning disability	10.0	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1

Graphical network of the top 20 diseases related to Geographic Tongue:

Symptoms & Phenotypes for Geographic Tongue

Sources:
²⁶GenomeRNAi, ⁴¹MGI, ⁶⁸UMLS
See all MalaCards sources

UMLS symptoms related to Geographic Tongue:

exanthema, glossalgia

GenomeRNAi Phenotypes related to Geographic Tongue according to GeneCards Suite gene sharing:

²⁶

id	Description	GenomeRNAi Source Accession	Score	Top Affiliating Genes
1	Increased shRNA abundance (Z-score > 2)	GR00366-A-192	6.7	EGFR, HLA-A, HLA-B, HLA-C, HLA-A, HLA-B

MGI Mouse Phenotypes related to Geographic Tongue according to GeneCards Suite gene sharing:

⁴¹

id	Description	MGI Source Accession	Score	Top Affiliating Genes
1	neoplasm	MP:0002006	7.8	CD79A, EGFR, EPHX1, NME1, TGM2, VEGFA
2	liver/biliary system	MP:0005370	7.7	CD79A, EGFR, HLA-DQB1, NME1, THEM5, VEGFA

Drugs & Therapeutics for Geographic Tongue

Sources:
¹BitterDB, ⁴ClinicalTrials, ⁷Cochrane Library, ¹⁰DGIdb, ¹⁴DrugBank, ²⁹HMDB, ³³IUPHAR, ⁵⁰Novoseek, ⁵⁶PharmGKB
See all MalaCards sources

Drugs for Geographic Tongue (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 14)

id

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Doxycycline

approved, investigational, vet_approved

Phase 4

243

564-25-0

54671203

Synonyms:

(2E,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(2Z,4S,4aR,5S,5aR,6R,12aS)-2-[amino(hydroxy)methylidene]-4-(dimethylamino)-5,10,11,12a-tetrahydroxy-6-methyl-4a,5,5a,6-tetrahydro-4H-tetracene-1,3,12-trione

(4S,4aR,5S,5aR,6R,12aS)-4-(dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

10597-92-9

17086-28-1 (mono-hydrate)

2-Naphthacenecarboxamide, 4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-, (4S,4aR,5S,5aR,6R,12aS)

24390-14-5

41411-66-9 (6-epimer, mono-hydrochloride)

5-Hydroxy-alpha-6-deoxytetracycline

5-hydroxy-α-6-deoxytetracycline

564-25-0

6-Deoxyoxytetracycline

6-Deoxytetracycline

6-alpha-Deoxy-5-oxytetracycline

6-alpha-deoxy-5-oxytetracycline

69935-17-7 (mono-hydrochloride, di-hydrate)

6alpha-Deoxy-5-oxytetracycline

6alpha-deoxy-5-oxytetracycline

6α-deoxy-5-oxytetracycline

7164-70-7

7264-10-0

94088-85-4 (calcium salt (1:2))

AB08 (*Fosfatex)

AC1NQXW7

AC1NS4CW

AC1NUYS8

AC1O8PYM

Alti-Doxycycline

Anhydrous doxycycline

Apo-Doxy

Atridox

Azudoxat

BCBcMAP01_000024

BIDD:GT0146

BMY-28689

BPBio1_000951

BSPBio_000863

BSPBio_001936

BU-3839T

C06973

CHEBI:50845

CHEMBL1433

CID5281011

CID5353597

CID5463943

CID6713981

CPD001550033

D07876

DB00254

DMSC (*Fosfatex)

DOXCYCLINE ANHYDROUS

DOXY

DOXYCYCLINE CALCIUM

DOXYCYCLINE MONOHYDRATE

Deoxymykoin

DivK1c_000345

Dossiciclina

Dossiciclina [DCIT]

Doxcycline anhydrous

Doxiciclina

Doxiciclina [INN-Spanish]

Doxiciclina [Italian]

Doxitard

Doxivetin

Doxy-Caps

Doxy-Puren

Doxy-Tabs

Doxycen

Doxychel

Doxychel (TN)

Doxycin

Doxycyclin

Doxycycline (200mg/day) or Placebo

Doxycycline (INN)

Doxycycline (TN)

Doxycycline (anhydrous)

Doxycycline (internal use)

Doxycycline Hyclate

Doxycycline Monohydrate

Doxycycline anhydrous

Doxycycline hyclate

Doxycycline-Chinoin

Doxycyclinum

Doxycyclinum [INN-Latin]

Doxysol

Doxytec

Doxytetracycline

EINECS 209-271-1

GS-3065 (*monohydrate)

HMS2090E06

HSDB 3071

Hydramycin

IDI1_000345

Investin

Jenacyclin

KBio1_000345

KBio2_001287

KBio2_003855

KBio2_006423

KBio3_001156

KBioGR_001133

KBioSS_001287

LS-187766

LS-93868

Liviatin

Lopac0_000405

MolPort-002-507-423

Monodox

Monodox (*monohydrate)

NCGC00161602-01

NCGC00161602-03

NCGC00161602-04

NCGC00167961-01

NCGC00179395-01

NINDS_000345

NSC633557

Novo-Doxylin

Nu-Doxycycline

Oracea

Prestwick0_000852

Prestwick1_000852

Prestwick2_000852

Prestwick3_000852

Ronaxan

SAM002589932

SMP1_000107

SPBio_000246

SPBio_002784

STOCK1N-34341

Spanor

Spectrum2_000143

Spectrum3_000408

Spectrum4_000527

Spectrum5_000947

Spectrum_000807

Supracyclin

UNII-334895S862

UPCMLD-DP021

UPCMLD-DP021:001

Vibra-tabs

Vibramycin

Vibramycin (*monohydrate)

Vibramycin Novum

Vibramycine

Vibravenos

Vivox (*Hyclate)

alpha-6-Deoxy-5-hydroxytetracycline

alpha-6-Deoxyoxytetracycline

alpha-Doxycycline

doxycycline

2

Penicillin V

approved, vet_approved

Phase 4

17

87-08-1

6869

Synonyms:

(2S,5R,6R)-3,3-DIMETHYL-7-OXO-6-(2-PHENOXYACETAMIDO)-4-THIA-1- AZABICYCLO(3.2.0)HEPTANE-2-CARBOXYLIC ACID

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-(2-phenoxyacetamido)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid

(2S,5R,6R)-3,3-Dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(2-phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-[(phenoxyacetyl)amino]-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-3,3-dimethyl-7-oxo-6-{[(phenyloxy)acetyl]amino}-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

1098-87-9 (mono-hydrochloride salt)

132-98-9

132-98-9 (mono-potassium salt)

147-48-8 (mono-hydrochloride salt)

2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carbonyl

2,2-dimethyl-6beta-[(phenoxyacetyl)amino]penam-3alpha-carboxylic acid

3,3-Dimethyl-7-oxo-6-((phenyloxyacetyl)amino)-4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid

3,3-dimethyl-6beta-[(phenoxyacetyl)amino]penam-2alpha-carboxylic acid (PIN)

4-27-00-05884 (Beilstein Handbook Reference)

6-Phenoxyacetamidopenicillanic acid

6-phenoxyacetamidopenicillanic acid

87-08-1

AB00514745

AC1L1NHG

AC1Q5QX3

AR-1H6492

Acipen V

Apocillin

Apopen

BRD-K43966364-237-02-2

BRN 0096259

BSPBio_002185

Beepen-VK

Beromycin

Beromycin, Penicillin

Berromycin, Penicillin

Betapen-VK

Bio-0630

C08126

C16H18N2O5S

CCRIS 752

CHEBI:27446

CHEBI:53706

CHEMBL615

CID6869

Calcipen

Compocillin V

Crystapen V

D05411

DB00417

DB08415

Distaquaine V

DivK1c_000779

EINECS 201-722-0

Eskacillian V

Eskacillin V

Fenacilin

Fenospen

Fenossimetilpenicillina

Fenossimetilpenicillina [DCIT]

Fenossimetilpenicillina [Dcit]

Fenoximetilpenicilina

Fenoximetilpenicilina [INN-Spanish]

Fenoxymethylpenicillin

Fenoxypen

HSDB 6314

IDI1_000779

KBio1_000779

KBio2_001487

KBio2_004055

KBio2_006623

KBio3_001685

KBioGR_000944

KBioSS_001487

LS-1861

MLS001304105

Meropenin

MolPort-002-515-462

NCGC00159342-02

NINDS_000779

Oracillin

Oratren

Ospen

P-Mega-Tablinen

PNV

PV

PVA

Pen-Oral

Pen-V

Pen-vee

Penapar-Vk

Penicillin Phenoxymethyl

Penicillin V

Penicillin V (USP)

Penicillin V Potassium

Penicillin V [USAN]

Penicillin phenoxymethyl

Penicillin, Phenoxymethyl

Penicillin-Vk

Phenocillin

Phenomycilline

Phenopenicillin

Phenoximethylpenicillinum

Phenoxomethylpenicillin

Phenoxymethyl Penicillin

Phenoxymethyl penicillin

Phenoxymethylenepenicillinic Acid

Phenoxymethylenepenicillinic acid

Phenoxymethylpenicillin

Phenoxymethylpenicillin (INN)

Phenoxymethylpenicillin Potassium

Phenoxymethylpenicilline

Phenoxymethylpenicilline [INN-French]

Phenoxymethylpenicillinic Acid

Phenoxymethylpenicillinic Acid Potassium Salt

Phenoxymethylpenicillinic acid potassium salt

Phenoxymethylpenicillinum

Phenoxymethylpenicillinum [INN-Latin]

Phénoxyméthylpénicilline

Robicillin

Rocilin

SMR000539431

SPBio_000389

Spectrum2_000495

Spectrum3_000543

Spectrum4_000472

Spectrum5_001409

Spectrum_001007

Stabicillin

UNII-Z61I075U2W

V-Cil

V-Cillin

V-Cillin (TN)

V-Cillin K

V-Cylina

V-Cyline

V-Tablopen

Vebecillin

Vegacillin

acipen-v

penicillin v

phenoxomethylpenicillanyl

phenoxomethylpenicillin

phenoxymethylpenicillanyl

phenoxymethylpenicillinic acid

3

Cefuroxime

approved

Phase 4

56

55268-75-2

5361202, 5479529

Synonyms:

(6R,7R)-3-(carbamoyloxymethyl)-7-[[(2Z)-2-(furan-2-yl)-2-methoxyiminoacetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(Carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(carbamoyloxy)methyl]-7-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-3-[(carbamoyloxy)methyl]-7-{[(2Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-(2-(2-Furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid 7(sup 2)-(Z)-(O-methyloxime) carbamate (ester)

153012-39-6

3-[(carbamoyloxy)methyl]-7beta-[(2Z)-2-(furan-2-yl)-2-(methoxyimino)acetamido]-3,4-didehydrocepham-4-carboxylic acid

55268-75-2

56238-63-2

AC-15028

AC-4539

AC1NUIFB

AC1Q41FS

Anaptivan

BIDD:GT0619

BPBio1_001033

BRD-K02733959-236-02-8

BRN 5783190

BSPBio_000939

Biociclin

Biofuroksym

Bioxima

C06894

C08108

C16H15N4O8S.Na

C16H16N4O8S

C4417_FLUKA

C4417_SIGMA

CEFUROXIME AND DEXTROSE IN DUPLEX CONTAINER

CEFUROXIME SODIUM

CHEBI:3515

CHEMBL1436

CID5479529

CID6523269

CPD0-2069

CXM

Cefofix

Cefumax

Cefurex

Cefuril

Cefuroxim

Cefuroxim AJ

Cefuroxim Fresenius

Cefuroxim Genericsn

Cefuroxim Hexal

Cefuroxim Lilly

Cefuroxim MN

Cefuroxim Norcox

Cefuroxim Norcox [inj.]

Cefuroxim curasan

Cefuroxima Fabra

Cefuroxima Richet

Cefuroxime

Cefuroxime (TN)

Cefuroxime (USAN/INN)

Cefuroxime [USAN:BAN:INN]

Cefuroxime [USAN:INN:BAN]

Cefuroxime for Injection and Dextrose for Injection in Duplex Container

Cefuroxime sodium (JP15/USP)

Cefuroxime sodium [USAN:BAN:JAN]

Cefuroxime sodium salt

Cefuroximine

Cefuroximo

Cefuroximo [INN-Spanish]

Cefuroximum

Cefuroximum [INN-Latin]

Cephuroxime

Cetroxil

Cetroxil [inj.]

Colifossim

Curocef

Curoxim

Curoxima

Curoxime

D00262

D00915

EINECS 259-560-1

EINECS 260-073-1

Froxal

Froxal [inj.]

Furoxil

KEFUROX IN PLASTIC CONTAINER

KS-1040

Kesint

Ketocef

LS-149936

LS-2226

Lifurox

Medoxim

MolPort-002-885-814

MolPort-005-938-003

Prestwick3_000720

Sharox

Sharox [inj.]

Sodium (6R,7R)-7-(2-(2-furyl)glyoxylamido)-3-(hydroxymethyl)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate, 7(sup 2)-(Z)-(O-methyloxime), carbamate (ester)

Sodium (6R-(6alpha,7beta(Z)))-3-(((aminocarbonyl)oxy)methyl)-7-(2-furyl(methoxyimino)acetamido)-8-oxo-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylate

Sodium cefuroxime

Spectrazolr

UNII-O1R9FJ93ED

UNII-R8A7M9MY61

Ultroxim

ZINACEF IN PLASTIC CONTAINER

Zinacef

Zinacef (TN)

Zinacef Danmark

Zinacef danmark

Zinnat [inj.]

cefuroxime

cefuroxime na

cefuroximesodium

4

Amoxicillin

approved, vet_approved

Phase 4

465

26787-78-0

33613, 2171

Synonyms:

(-)-6-(2-Amino-2-(P-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo-(3.2.0)heptane-2-carboxylic acid

(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

(2S,5R,6R)-6-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid

26787-78-0

33911-69-2

34642-77-8 (mono-hydrochloride salt)

4-Thia-1-azabicyclo(3.2.0)heptane-2-carboxylic acid, 6-(2-amino-2-(p-hydroxyphenyl)acetamido)-3,3-dimethyl-7-oxo-, D- (8CI)

6-(D-(-)-alpha-Amino-p-hydroxyphenylacetamido)penicillanic acid

6-(D-(-)-p-Hydroxy-alpha-aminobenzyl)penicillin

6-(a-Amino-4-hydroxyphenylacetamido)penicillanic acid

6-(p-Hydroxy-alpha-aminophenylacetamido)penicillanic acid

6-(p-hydroxy-α-aminophenylacetamido)penicillanic acid

6-[[Amino(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 9CI

61336-70-7 (TRIHYDRATE)

6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carbonyl

6beta-[(2R)-2-amino-2-(4-hydroxyphenyl)acetamido]-2,2-dimethylpenam-3alpha-carboxylic acid

71447-36-4

81030-75-3

AC-12263

AC1L1PY2

AMC

AMOXICILLIN CRYSTALLINE

AMOXICILLIN PEDIATRIC

AMPC

AUGMENTIN '125'

AUGMENTIN '200'

AUGMENTIN '250'

AUGMENTIN '400'

AUGMENTIN '500'

AUGMENTIN '875'

AUGMENTIN ES-600

AX

Actimoxi

Almodan

Ambap26787-78-0

Amix

Amoclen

Amolin

Amopen

Amopenixin

Amoram

Amox

Amox 250 Cap 250mg

Amox 500 Cap 500mg

Amox S 125 Sus 125mg/5ml

Amox S 250 Sus 250mg/5ml

Amoxi

Amoxi-Mast

Amoxi-mast

Amoxibiotic

Amoxicaps

Amoxicilina

Amoxicilina [INN-Spanish]

Amoxicillin (INN)

Amoxicillin (TN)

Amoxicillin (anhydrous)

Amoxicillin (inn)

Amoxicillin Trihydrate

Amoxicillin and clavulanate potassium

Amoxicillin anhydrous

Amoxicillin pediatric

Amoxicillin trihydrate

Amoxicillin(usan)

Amoxicilline

Amoxicilline [INN-French]

Amoxicilline [INN]

Amoxicilline [inn]

Amoxicillinum

Amoxicillinum [INN-Latin]

Amoxid

Amoxiden

Amoxil

Amoxivet

Amoxycillin

Amoxycillin Trihydrate

Amoxycillin trihydrate

Amoxycillin, BAN

Amoxymed

Amrit

Anemolin

Apo-Amoxi

Apo-Amoxi Cap 250mg

Apo-Amoxi Cap 500mg

Apo-Amoxi Pwr for Susp 125mg/5ml

Apo-Amoxi Pwr for Susp 250mg/5ml

Apo-amoxi

Apo-amoxi sugar free

Aspenil

BL-P 1410

BLP 1410

BPBio1_000499

BRD-K55044200-001-03-9

BRL 2333

BRL-2333

BSPBio_000453

Biomox

Bristamox

C06827

CHEBI:2676

CHEBI:53712

CHEMBL1082

CID33613

CPD000058707

Cemoxin

Clamoxyl

Clamoxyl (SKB)

D-(-)-alpha-Amino-p-hydroxybenzyl penicillin

D-(-)-alpha-Amino-p-hydroxybenzylpenicillin

D-(alpha-Amino-p-hydroxybenzyl)penicillin

D-2-Amino-2-(4-hydroxyphenyl)acetamidopenicillanic acid

D-Amoxicillin

D07452

DB01060

Delacillin

DisperMox

Dispermox

EINECS 248-003-8

Efpenix

Flemoxin

Galenamox

Gen-Amoxicillin 250mg

Gen-Amoxicillin 500mg

HMS1569G15

HSDB 3204

Hiconcil

Histocillin

Hydroxyampicillin

Ibiamox

Imacillin

LS-149721

Lamoxy

Larotid

MLS000028632

MLS002222248

Metafarma capsules

Metifarma capsules

MolPort-003-981-182

MolPort-005-933-687

Moxacin

Moxal

Moxatag

NCGC00179554-01

NSC 277174

NSC277174

Novamoxin Cap 250mg

Novamoxin Cap 500mg

Novamoxin Sus 125mg/5ml

Novamoxin Sus 250mg/5ml

Nu-Amoxi Cap 250mg

Nu-Amoxi Cap 500mg

Nu-Amoxi Sus 125/5ml

Nu-Amoxi Sus 250mg/5ml

Ospamox

P-Hydroxyampicillin

PHL-amoxicillin

PMS-amoxicillin

Pamoxicillin

Piramox

Polymox

Prestwick0_000357

Prestwick1_000357

Prestwick2_000357

Prestwick3_000357

Prestwick_713

Prevpac

Pro Amox Pwr for Oral Susp 125mg/5ml

Pro Amox-250 Cap 250mg

Pro Amox-500 Cap 500mg

Pro-Amox-250 Orl Sus 250mg/5ml

R-Hydroxyampicillin

Rimoxallin

Ro 10-8756

Robamox

SAM002264592

SMR000058707

SPBio_002374

Sauracillin

Sawamox PM

Sumox

Tolodina

Trimox

Unicillin

Utimox

Vetramox

Wymox

Zimox

alpha-Amino-p-hydroxybenzylpenicillin

amoxicillanyl

amoxicillin

p-Hydroxyampicillin

α-amino-p-hydroxybenzylpenicillin

5

Anti-Bacterial Agents

Phase 4, Phase 1, Phase 2

11226

6

Antiprotozoal Agents

Phase 4

2051

7

Anti-Infective Agents

Phase 4, Phase 1, Phase 2

22062

8

Antimalarials

Phase 4

1246

9

Antiparasitic Agents

Phase 4

2199

10

penicillins

Phase 4

114

11

cefuroxime axetil

Phase 4

56

12

Antibiotics, Antitubercular

Phase 4, Phase 1, Phase 2

7180

13

Ceftriaxone

approved

119

73384-59-5

5479530, 5361919

Synonyms:

(6R,7R)-7-(2-(2-Amino-4-thiazolyl)glyoxylamido)-8-oxo-3-(((1,2,5,6-tetrahydro-2-methyl-5,6-dioxo-as-triazin-3-yl)thio)methyl)-5-thia-1-azabicyclo(4.2.0)oct-2-ene-2-carboxylic acid, 7(sup 2)-(Z)-(O-methyloxime), sesquaterhydrate

(6R,7R)-7-({(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-[(methyloxy)imino]acetyl}amino)-3-{[(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-1,2,4-triazin-3-yl)thio]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-[[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-[(2-methyl-5,6-dioxo-1H-1,2,4-triazin-3-yl)sulfanylmethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

(6R,7R)-7-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid

104376-79-6

104376-79-6 (di-hydrochloride salt)

73384-59-5

74578-69-1 (di-hydrochloride salt, hemiheptahydrate)

7beta-{[(2Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino}-3-{[(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-yl)sulfanyl]methyl}-3,4-didehydrocepham-4-carboxylic acid

AC-1592

AC1NUIFE

Biotrakson

C06683

C18H18N8O7S3

CEFTRIAXONE SODIUM

CHEBI:29007

CHEMBL161

CID5479530

CTRX

Cefatriaxone

Ceftriaxon

Ceftriaxona

Ceftriaxona [INN-Spanish]

Ceftriaxone (INN)

Ceftriaxone (TN)

Ceftriaxone [USAN:JAN]

Ceftriaxone intravenous

Ceftriaxone, Disodium Salt

Ceftriaxone, Disodium Salt, Hemiheptahydrate

Ceftriaxonum

Ceftriaxonum [INN-Latin]

Ceftriazone

D07659

DB01212

DRG-0071

EINECS 277-405-6

LS-150031

Longacef

Longaceph

MolPort-005-933-495

Ro 139904

Ro-13-9904

Ro13-9904

Rocefin

Rocephin

Rocephine

UNII-75J73V1629

ceftriaxone

14

Antitubercular Agents

1343

Interventional clinical trials:

(show all 17)

id	Name	Status	NCT ID	Phase
1	Comparison of Doxycycline and Cefuroxime Axetil for Treatment of Erythema Migrans: Clinical and Microbiological Outcome	Completed	NCT01518192	Phase 4
2	Comparing 3 Antibiotic Regimes for Erythema Migrans in General Practice	Completed	NCT01368341	Phase 4
3	Xenodiagnosis After Antibiotic Treatment for Lyme Disease	Recruiting	NCT02446626	Phase 1, Phase 2
4	Lyme Borreliosis and Early Cutaneous Diagnostic	Unknown status	NCT02414789
5	Doxycycline and Ceftriaxone in Suspected Early Lyme Neuroborreliosis	Unknown status	NCT00942006
6	The Relationship Between Allergic Rhinitis and Geographic Tongue	Unknown status	NCT01454492
7	Duration of Antibiotic Treatment of Erythema Migrans	Completed	NCT00910715
8	Doxycycline in Therapy of Erythema Migrans	Completed	NCT01475708
9	Culture Media for Borrelia Burgdorferi Sensu Lato	Completed	NCT02145754
10	Searching for Persistence of Infection in Lyme Disease	Completed	NCT01143558	Early Phase 1
11	Cytokines and Chemokines in Erythema Migrans	Recruiting	NCT02147249
12	Antibiotic Treatment of Multiple Erythema Migrans	Recruiting	NCT01163994
13	Analysis of Lyme Disease Lesions	Recruiting	NCT00132327
14	Borrelia Species in Cutaneous Lyme Borreliosis	Recruiting	NCT00576082
15	A Multicenter Study to Evaluate a Borrelia Diagnostic Test in Subjects With Early Stage or Late Stage Lyme Disease	Recruiting	NCT02741609
16	Duration of Doxycycline Treatment in EM Patients	Not yet recruiting	NCT03153267
17	Investigation of Southern Tick-Associated Rash Illness (STARI)	Terminated	NCT00358761

Search NIH Clinical Center for Geographic Tongue

Cochrane evidence based reviews: glossitis, benign migratory

Genetic Tests for Geographic Tongue

Anatomical Context for Geographic Tongue

Sources:
³⁶MalaCards
See all MalaCards sources

MalaCards organs/tissues related to Geographic Tongue:

³⁶

Tongue, Skin

Publications for Geographic Tongue

Sources:
⁵⁷PubMed
See all MalaCards sources

Articles related to Geographic Tongue:

(show all 49)

id	Title	Authors	Year
1	Oral medicine: Factors associated with geographic tongue and fissured tongue. (27388082)		2016
2	Geographic tongue. (27505875)	Jacob C.N.... R J.	2016
3	Mutations in IL36RN are associated with geographic tongue. (27900482)	Liang J.... Yao Z.	2016
4	Geographic tongue and psoriasis: clinical, histopathological, immunohistochemical and genetic correlation - a literature review. (27579734)	Picciani B.L.... Carneiro S.	2016
5	Geographic tongue associated with sialadenitis. (27726175)	Ikeda A.... Yamamoto O.	2016
6	Treatment of Symptomatic Geographic Tongue with Triamcinolone Acetonide Alone and in Combination with Retinoic Acid: A Randomized Clinical Trial. (27536325)	Najafi S.... Kharrazifard M.J.	2016
7	Paediatric Geographic Tongue: A Case Report, Review and Recent Updates. (27042597)	Nandini D.B.... Ashwini R.	2016
8	IMAGES IN CLINICAL MEDICINE. Geographic Tongue. (26886524)	Varoni E.... Decani S.	2016
9	The prevalence of celiac disease in patients with geographic tongue. (27131886)	Cigic L.... Biocina Lukenda D.	2016
10	Geographic Tongue. (27436616)	Bakshi S.S.... Bhattacharjee S.	2016
11	Geographic tongue and fissured tongue in 348 patients with psoriasis: correlation with disease severity. (25685842)	Picciani B.L.... Dias E.P.	2015
12	Factors associated with geographic tongue and fissured tongue. (26381370)	Dafar A.... Jontell M.	2015
13	Prevalence of Geographic tongue and Related Predisposing Factors in 7-18 Year-Old Students in Kermanshah, Iran 2014. (26156909)	Rezaei F.... Tavakoli P.	2015
14	Psychological parameters associated with geographic tongue: a clinical observation. (25482552)	Khalighinejad N.... Gorsky M.	2015
15	Psychological parameters associated with geographic tongue: a clinical observation. (25482551)	Stoopler E.T.... Sollectio T.P.	2015
16	Geographic tongue in monozygotic twins. (24959517)	Shekhar M G.	2014
17	Immunologic and psychologic parameters associated with geographic tongue. (24842481)	Alikhani M.... Gorsky M.	2014
18	Medical image. A benign glossal lesion. Geographic tongue. (24929575)	Gupta T.... Kansal N.K.	2014
19	Case of the month. Ectopic geographic tongue (erythema migrans). (24937889)	Kacher J.E.	2014
20	Relation between psoriasis and geographic tongue. (25584342)	Tarakji B.... Sarraj F.	2014
21	A possible relationship of human leucocyte antigens with psoriasis vulgaris and geographic tongue. (25176018)	Picciani B.L.... Dias E.P.	2014
22	Treatment of geographic tongue with topical tacrolimus. (25085945)	Purani J.M.... Purani H.J.	2014
23	The comparison of salivary level of estrogen and progesterone in 1(st) , 2(nd) and 3(rd) trimester in pregnant women with and without geographic tongue. (24348617)	Ghalayani P.... Khalighinejad N.	2013
24	Oral and maxillofacial pathology case of the month. Erythema migrans (ectopic migratory glossitis/ectopic geographic tongue). (24236384)	Raja R.... Vigneswaran N.	2013
25	Geographic tongue and tenofovir. (23598934)	Ferreira A.O.... Costa J.B.	2013
26	Geographic tongue induced by angiogenesis inhibitors. (23576484)	Hubiche T.... Sibaud V.	2013
27	Geographic Tongue and Associated Risk Factors among Iranian Dental Patients. (23515238)	Honarmand M.... Sehhatpour M.	2013
28	Increased prevalence of geographic tongue in burning mouth complaints: a retrospective study. (22901641)	Ching V.... Su N.	2012
29	Migratory stomatitis (ectopic geographic tongue) on the floor of the mouth. (21763590)	Zadik Y.... Pallmon S.	2011
30	Geographic tongue treated with topical tacrolimus. (21886753)	Ishibashi M.... Aiba S.	2010
31	Images in clinical medicine. Geographic tongue. (19907039)	Masferrer E.... Jucgla A.	2009
32	Allergic contact stomatitis presenting as geographical tongue with pruritus. (19207382)	Waroquier D.... Parent D.	2009
33	Oral medicine case book 7. Migratory stomatitis and geographic tongue. (18689340)	Dreyer W.P.... de Waal J.	2008
34	Ectopic geographic tongue--a case report. (17432777)	Borrie F.... Macintyre D.	2007
35	Recurrent geographical tongue and fissured tongue in association with pregnancy. (17243991)	Yun S.J.... Lee S.C.	2007
36	Prevalence and risk factors associated with geographic tongue among US adults. (16792723)	Shulman J.D.... Carpenter W.M.	2006
37	The prevalence and significance of fissured tongue and geographical tongue in psoriatic patients. (16487088)	Zargari O.	2006
38	Geographic tongue: clinical characteristics of 188 cases. (15719084)	Jainkittivong A.... Langlais R.P.	2005
39	Geographic tongue: literature review and case reports. (16161818)	Pass B.... Childers E.L.	2005
40	Painful geographic tongue (benign migratory glossitis) in a child. (15482313)	Menni S.... Crosti C.	2004
41	Prevalence of fissured tongue, geographic tongue and median rhomboid glossitis among Israeli adults of different ethnic origins. (15316160)	Yarom N.... Gorsky M.	2004
42	Benign migratory glossitis or geographic tongue: an enigmatic oral lesion. (12517366)	Assimakopoulos D.... Elisaf M.	2002
43	Geographic tongue (migrant glossitis) and psoriasis. (11535977)	Femiano F.	2001
44	Melkersson - rosenthal syndrome with geographical tongue. (20944302)	Thami G.P.... Kanwar A.J.	1997
45	Occurrence of fissured tongue, geographic tongue and filiform atrophy among dental patients in Saudi Arabia. (3867320)	Mani N.J.	1985
46	Prevalence of geographic tongue, fissured tongue, median rhomboid glossitis, and hairy tongue among 3,611 Minnesota schoolchildren. (5270895)	Redman R.S.	1970
47	Incidence of geographic tongue and median rhomboid glossitis in 3,319 Negro college students. (5245682)	Richardson E.R.	1968
48	SIMULATANEOUS OCCURRENCE OF GEOGRAPHIC TONGUE AND HAIRY TONGUE. (14315909)	GIACOMELLI J.F.	1965
49	Some observations on 1246 cases of geographic tongue: the association between geographic tongue, seborrheic dermatitis, and spasmodic bronchitis; transition of geographic tongue to fissured tongue. (13410386)	RAHAMIMOFF P.... MUHSAM H.V.	1957

Genes related to Geographic Tongue

Sources:
¹³DISEASES, ²¹GeneCards
See all MalaCards sources

Genes related to Geographic Tongue:

(show all 18)

- Elite gene

- Cancer Census gene in COSMIC

id	Symbol	Description	Score	Implication
1	IL36RN	Interleukin 36 Receptor Antagonist	25.05	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
2	HLA-A	Major Histocompatibility Complex, Class I, A	23.89	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
3	HLA-DQB2	Major Histocompatibility Complex, Class II, DQ Beta 2	23.63	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
4	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	23.52	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
5	AKTIP	AKT Interacting Protein	23.20	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
6	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	23.00	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
7	EPHX1	Epoxide Hydrolase 1	22.95	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
8	HLA-C	Major Histocompatibility Complex, Class I, C	22.82	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
9	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	22.39	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
10	HLA-B	Major Histocompatibility Complex, Class I, B	22.36	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
11	TNFRSF10B	TNF Receptor Superfamily Member 10b	22.16	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
12	TGM2	Transglutaminase 2	22.13	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
13	CD79A	CD79a Molecule	21.64	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
14	BRD4	Bromodomain Containing 4	18.49	GeneCards inferred via : Disorders (show sections)
15	WHRN	Whirlin	13.87	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
16	THEM5	Thioesterase Superfamily Member 5	13.85	DISEASES inferred ¹³ GeneCards inferred via : Disorders (show sections)
17	EGFR	Epidermal Growth Factor Receptor	13.33	DISEASES inferred ¹³
18	VEGFA	Vascular Endothelial Growth Factor A	13.20	DISEASES inferred ¹³

Variations for Geographic Tongue

Expression for genes affiliated with Geographic Tongue

Sources:
¹⁸Gene Expression Omnibus DataSets
See all MalaCards sources

Search GEO for disease gene expression data for Geographic Tongue.

Pathways for genes affiliated with Geographic Tongue

Sources:
³⁴KEGG, ⁴²NCBI BioSystems Database, ⁵⁵PathCards, ⁵⁸QIAGEN, ⁶⁰Reactome, ⁶⁵Thomson Reuters
See all MalaCards sources

Pathways related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 17)

id	Super pathways	Score	Top Affiliating Genes
1	Translocation of ZAP-70 to Immunological synapse⁶⁰ Show member pathways Generation of second messenger molecules⁶⁰ PD-1 signaling⁶⁰ Phosphorylation of CD3 and TCR zeta chains⁶⁰	9.8	HLA-DQB1, HLA-DQB2, HLA-DRB1
2	MHC class II antigen presentation⁶⁰	9.8	HLA-DQB1, HLA-DQB2, HLA-DRB1
3	Antigen Presentation- Folding, assembly and peptide loading of class I MHC⁶⁰	9.7	HLA-A, HLA-B, HLA-C
4	Rheumatoid arthritis³⁴	9.5	HLA-DQB1, HLA-DRB1, VEGFA
5	Immune response Role of DAP12 receptors in NK cells⁶⁵ Show member pathways Immune response CD16 signaling in NK cells⁶⁵ Natural killer cell mediated cytotoxicity³⁴	9.3	HLA-A, HLA-B, HLA-C, TNFRSF10B
6	Cell adhesion molecules (CAMs)³⁴	9.2	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1
7	HTLV-I infection³⁴	9.2	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1
8	Epstein-Barr virus infection³⁴	9.2	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1
9	Phagosome³⁴	9.2	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1
10	Interferon gamma signaling⁶⁰ Show member pathways Interferon Signaling⁶⁰ Regulation of IFNG signaling⁶⁰	9.0	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
11	G-protein signaling N-RAS regulation pathway⁶⁵ Show member pathways Immune response Antigen presentation by MHC class II⁶⁵	8.9	EGFR, HLA-DQB1, HLA-DQB2, HLA-DRB1
12	Endocytosis³⁴	8.8	EGFR, HLA-A, HLA-B, HLA-C
13	Influenza A³⁴ Show member pathways Herpes simplex infection³⁴ Measles³⁴	8.8	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1, TNFRSF10B
14	Allograft rejection⁴² ³⁴ Show member pathways Allograft Rejection⁴² Viral myocarditis³⁴ Asthma³⁴ CTL Mediated Apoptosis⁵⁸ Intestinal immune network for IgA production³⁴ Autoimmune thyroid disease³⁴ Type I diabetes mellitus³⁴ Graft-versus-host disease³⁴ Antigen processing and presentation³⁴ THC Differentiation Pathway⁵⁸	8.7	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1, VEGFA
15	Actin Nucleation by ARP-WASP Complex⁵⁸ Show member pathways CDC42 Pathway⁵⁸ Actin Nucleation and Branching⁵⁸ RhoA Pathway⁵⁸	8.4	EGFR, HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1
16	Class I MHC mediated antigen processing and presentation⁶⁰ Show member pathways Antigen processing- Ubiquitination and Proteasome degradation⁶⁰ Adaptive Immune System⁶⁰	7.7	CD79A, EGFR, HLA-A, HLA-B, HLA-C, HLA-DQB1
17	Cytokine Signaling in Immune system⁶⁰ Show member pathways Signaling by Interleukins⁶⁰	7.6	EGFR, HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2

GO Terms for genes affiliated with Geographic Tongue

Sources:
¹⁹Gene Ontology
See all MalaCards sources

Cellular components related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 15)

id	Name	GO ID	Score	Top Affiliating Genes
1	clathrin-coated endocytic vesicle membrane	GO:0030669	10.5	HLA-DQB1, HLA-DQB2, HLA-DRB1
2	endocytic vesicle membrane	GO:0030666	10.5	HLA-DQB1, HLA-DQB2, HLA-DRB1
3	MHC class II protein complex	GO:0042613	10.4	HLA-DQB1, HLA-DQB2, HLA-DRB1
4	MHC class I protein complex	GO:0042612	10.3	HLA-A, HLA-B, HLA-C
5	phagocytic vesicle membrane	GO:0030670	10.2	HLA-A, HLA-B, HLA-C
6	trans-Golgi network membrane	GO:0032588	10.2	HLA-DQB1, HLA-DQB2, HLA-DRB1
7	recycling endosome membrane	GO:0055038	10.2	HLA-A, HLA-B, HLA-C
8	transport vesicle membrane	GO:0030658	9.8	HLA-DQB1, HLA-DQB2, HLA-DRB1
9	ER to Golgi transport vesicle membrane	GO:0012507	9.6	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
10	endosome membrane	GO:0010008	9.6	EGFR, HLA-DQB1, HLA-DQB2, HLA-DRB1
11	early endosome membrane	GO:0031901	9.6	EGFR, HLA-A, HLA-B, HLA-C
12	integral component of lumenal side of endoplasmic reticulum membrane	GO:0071556	9.6	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
13	Golgi membrane	GO:0000139	8.8	EGFR, HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2
14	cell surface	GO:0009986	8.5	EGFR, HLA-A, HLA-B, HLA-C, HLA-DRB1, TNFRSF10B
15	endoplasmic reticulum	GO:0005783	8.4	EGFR, EPHX1, HLA-A, HLA-B, HLA-C, HLA-DQB2

Biological processes related to Geographic Tongue according to GeneCards Suite gene sharing:

(show all 16)

id	Name	GO ID	Score	Top Affiliating Genes
1	humoral immune response mediated by circulating immunoglobulin	GO:0002455	10.7	HLA-DQB1, HLA-DRB1
2	immunoglobulin production involved in immunoglobulin mediated immune response	GO:0002381	10.7	HLA-DQB1, HLA-DRB1
3	protection from natural killer cell mediated cytotoxicity	GO:0042270	10.6	HLA-A, HLA-B
4	antigen processing and presentation of exogenous peptide antigen via MHC class II	GO:0019886	10.5	HLA-DQB1, HLA-DQB2, HLA-DRB1
5	antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	GO:0002504	10.5	HLA-DQB1, HLA-DQB2, HLA-DRB1
6	T cell costimulation	GO:0031295	10.4	HLA-DQB1, HLA-DQB2, HLA-DRB1
7	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent	GO:0002479	10.4	HLA-A, HLA-B, HLA-C
8	antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-independent	GO:0002480	10.4	HLA-A, HLA-B, HLA-C
9	antigen processing and presentation of peptide antigen via MHC class I	GO:0002474	10.4	HLA-A, HLA-B, HLA-C
10	type I interferon signaling pathway	GO:0060337	10.3	HLA-A, HLA-B, HLA-C
11	antigen processing and presentation	GO:0019882	9.7	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
12	interferon-gamma-mediated signaling pathway	GO:0060333	9.6	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
13	positive regulation of epithelial cell proliferation	GO:0050679	9.5	EGFR, NME1, VEGFA
14	immune system process	GO:0002376	9.3	CD79A, HLA-A, HLA-B, HLA-C, HLA-DQB2, HLA-DRB1
15	immune response	GO:0006955	9.1	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1
16	viral process	GO:0016032	9.0	BRD4, HLA-A, HLA-B, HLA-C, HLA-DRB1

Molecular functions related to Geographic Tongue according to GeneCards Suite gene sharing:

id	Name	GO ID	Score	Top Affiliating Genes
1	MHC class II receptor activity	GO:0032395	10.2	HLA-DQB1, HLA-DQB2, HLA-DRB1
2	peptide antigen binding	GO:0042605	9.0	HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DQB2, HLA-DRB1