MCID: GRS001
MIFTS: 37

Gerstmann Syndrome malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Gerstmann Syndrome

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Sources:
11Disease Ontology, 13DISEASES, 31ICD10 via Orphanet, 39MeSH, 40MESH via Orphanet, 48NIH Rare Diseases, 49NINDS, 54Orphanet, 62SNOMED-CT, 68UMLS, 69UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Gerstmann Syndrome:

Name: Gerstmann Syndrome 11 48 54 39 13 68
Developmental Gerstmann's Syndrome 68
Developmental Gerstmann Syndrome 48
Aphasia-Angular Gyrus Syndrome 11
 
Gerstmann Badal Syndrome 48
Gerstmann's Syndrome 49
Gerstmann Tetrad 48
Gs 48

Classifications:



External Ids:

Disease Ontology11 DOID:4969
MeSH39 D005862
Orphanet54 ORPHA221117
SNOMED-CT62 36785009
ICD10 via Orphanet31 F81.2
MESH via Orphanet40 D005862
UMLS via Orphanet69 C0017494

Summaries for Gerstmann Syndrome

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NINDS:49 Gerstmann's syndrome is a cognitive impairment that results from damage to a specific area of the brain -- the left parietal lobe in the region of the angular gyrus. It may occur after a stroke or in association with damage to the parietal lobe. It is characterized by four primary symptoms: a writing disability (agraphia or dysgraphia), a lack of understanding of the rules for calculation or arithmetic (acalculia or dyscalculia), an inability to distinguish right from left, and an inability to identify fingers (finger agnosia). The disorder should not be confused with

MalaCards based summary: Gerstmann Syndrome, also known as developmental gerstmann's syndrome, is related to pseudohypoparathyroidism and pseudohypoparathyroidism ic, and has symptoms including agraphia, acalculia and finger agnosia. An important gene associated with Gerstmann Syndrome is CBS (Cystathionine-Beta-Synthase), and among its related pathways are IL12-mediated signaling events and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include left parietal lobe, parietal lobe and brain.

Disease Ontology:11 A nervous system disease that results from damage located in left parietal lobe, has symptom agraphia, has symptom acalculia, has symptom finger agnosia.

Wikipedia:71 Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms... more...

Related Diseases for Gerstmann Syndrome

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Diseases related to Gerstmann Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 154)
idRelated DiseaseScoreTop Affiliating Genes
1pseudohypoparathyroidism11.1
2pseudohypoparathyroidism ic10.9
3gnas hyperfunction10.9
4finger agnosia10.8
5glutamine deficiency, congenital10.8
6megaloblastic anemia-1, finnish type10.8
7griscelli syndrome, type 210.8
8gitelman syndrome10.8
9mccune-albright syndrome, somatic, mosaic10.8
10pseudohypoparathyroidism, type ib10.8
11gilbert syndrome10.8
12adenoma10.1
13thyroiditis10.1
14neuroblastoma10.0
15glioma10.0
16ocular hypertension10.0CD4, CD8A
17arteriovenous malformation10.0CD4, CD8A
18meckel's diverticulitis10.0CD4, CD8A
19scrotum squamous cell carcinoma10.0CD4, CD8A
20acute cystitis10.0CD4, CD8A
21folliculitis10.0CD4, CD8A
22cd3gamma deficiency10.0CD4, CD8A
23vaccinia10.0CD4, CD8A
24esophagus carcinoma in situ10.0CD4, CD8A
25keratoconjunctivitis10.0CD4, CD8A
26intestinal disaccharidase deficiency10.0CD4, CD8A
27penis basal cell carcinoma10.0CD4, CD8A
28chronic eosinophilic pneumonia10.0CD4, CD8A
29psoriasis10.0CD4, CD8A
30inhalation anthrax10.0CD4, CD8A
31neurotic excoriation10.0CD4, CD8A
32total internal ophthalmoplegia10.0CD4, CD8A
33soft palate cancer10.0CD4, CD8A
34agammaglobulinemia, microcephaly, and severe dermatitis10.0CD4, CD8A
35aphasia10.0
36malignant eyelid melanoma10.0CD4, CD8A
37scleral disease10.0CD4, CD8A
38conventional leiomyosarcoma10.0CD4, CD8A
39partial third-nerve palsy10.0CD4, CD8A
40complex partial epilepsy10.0CD4, CD8A
41kidney rhabdoid cancer10.0CD4, CD8A
42endometrioid ovary carcinoma10.0CD4, CD8A
43postcricoid region cancer10.0CD4, CD8A
44cauda equina syndrome9.9CD4, CD8A
45pneumonic tularemia9.9CD4, CD8A
46capgras syndrome9.9CD4, CD8A
47yellow fever9.9CD4, CD8A
48alkhurma hemorrhagic fever9.9CD4, CD8A
49autonomic peripheral neuropathy9.9CD4, CD8A
50vaginal squamous tumor9.9CD4, CD8A

Graphical network of the top 20 diseases related to Gerstmann Syndrome:



Diseases related to gerstmann syndrome

Symptoms & Phenotypes for Gerstmann Syndrome

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Symptoms:

 11
  • agraphia
  • acalculia
  • finger agnosia

UMLS symptoms related to Gerstmann Syndrome:


hemiasomatognosia, altered pitch perception, autoscopy, amimia, hemiapraxia, cortical dysfunction nec, neurologic neglect syndrome, specific learning problem, other and unspecified symbolic dysfunctions, visual agnosia

Drugs & Therapeutics for Gerstmann Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Gerstmann Syndrome


Cochrane evidence based reviews: gerstmann syndrome

Genetic Tests for Gerstmann Syndrome

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Anatomical Context for Gerstmann Syndrome

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MalaCards organs/tissues related to Gerstmann Syndrome:

36
Parietal lobe, Brain

FMA organs/tissues related to Gerstmann Syndrome:

17
Left parietal lobe

Publications for Gerstmann Syndrome

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Articles related to Gerstmann Syndrome:

(show all 30)
idTitleAuthorsYear
1
With a Smile Through Tears": The Uprooted Career of the Man Behind Gerstmann Syndrome. (25259646)
2014
2
Mirror visual feedback for right-left discrimination in a patient with developmental Gerstmann syndrome. (24515713)
2014
3
Developmental Gerstmann syndrome in a young Taiwanese male: a case report. (19540897)
2009
4
A disconnection account of Gerstmann syndrome: functional neuroanatomy evidence. (19938150)
2009
5
Writing, calculating, and finger recognition in the region of the angular gyrus: a cortical stimulation study of Gerstmann syndrome. (14567608)
2003
6
The Gerstmann syndrome in Alzheimer's disease. (11861708)
2002
7
Gerstmann syndrome in systemic lupus erythematosus: neuropsychological, neuroimaging and spectroscopic findings. (11788743)
2001
8
Acetazolamide-induced Gerstmann syndrome. (10692744)
1999
9
A pure case of Gerstmann syndrome with a subangular lesion. (10356063)
1999
10
Toe agnosia in Gerstmann syndrome. (9328265)
1997
11
Left atrial myxoma presenting as Gerstmann syndrome. (8548463)
1996
12
Gerstmann syndrome: a case report. (2249447)
1990
13
Developmental Gerstmann syndrome: case report and review of the literature. (3611364)
1987
14
Gerstmann syndrome without aphasia: a longitudinal study. (6537237)
1984
15
Piagetian theory and the atypical case: an analysis of the developmental Gerstmann syndrome. (7229539)
1981
16
Echoacousia in Gerstmann syndrome. (712970)
1978
17
Dyscalculia and elements of the developmental Gerstmann syndrome in school children. (679700)
1978
18
Disorders of oculomotor scanning and graphic orientation in developmental Gerstmann syndrome. (618563)
1978
19
Reflections on the Gerstmann syndrome. (318903)
1977
20
Gerstmann syndrome without aphasia: a reply to Poeck and Orgass. (1204370)
1975
21
Gerstmann syndrome without aphasia: comments on the paper by Strub and Geschwind. (1204369)
1975
22
Gerstmann syndrome without aphasia. (4452255)
1974
23
Developmental Gerstmann syndrome. (5461058)
1970
24
Some posthumous notes on the Gerstmann syndrome. (4245825)
1970
25
Developmental Gerstmann syndrome. (4174929)
1968
26
The developmental Gerstmann syndrome. (14032921)
1963
27
Neuro-ophthalmic aspects of the Gerstmann syndrome. A case report. (14456348)
1962
28
Some notes on the Gerstmann syndrome. (13483851)
1957
29
An early description of the Gerstmann syndrome. (13378586)
1956
30
The Gerstmann syndrome; case report and review of the literature. (20291825)
1947

Variations for Gerstmann Syndrome

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Expression for genes affiliated with Gerstmann Syndrome

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Search GEO for disease gene expression data for Gerstmann Syndrome.

Pathways for genes affiliated with Gerstmann Syndrome

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GO Terms for genes affiliated with Gerstmann Syndrome

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Cellular components related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:00098979.5CD4, CD8A
2T cell receptor complexGO:00421019.1CD4, CD8A

Biological processes related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of calcium-mediated signalingGO:00508509.7CD4, CD8A
2T cell activationGO:00421109.7CD4, CD8A
3transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.1CD4, CD8A

Molecular functions related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.8CD4, CD8A
2protein homodimerization activityGO:00428038.5CBS, CD4, CD8A

Sources for Gerstmann Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet