MCID: GRS001
MIFTS: 39

Gerstmann Syndrome malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Gerstmann Syndrome

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Sources:
11Disease Ontology, 46NIH Rare Diseases, 13DISEASES, 52Orphanet, 37MeSH, 66UMLS, 47NINDS, 38MESH via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Gerstmann Syndrome:

Name: Gerstmann Syndrome 11 46 13 52 37 66
Developmental Gerstmann's Syndrome 66
Developmental Gerstmann Syndrome 46
Aphasia-Angular Gyrus Syndrome 11
 
Gerstmann Badal Syndrome 46
Gerstmann's Syndrome 47
Gerstmann Tetrad 46
Gs 46

Classifications:



External Ids:

Disease Ontology11 DOID:4969
MeSH37 D005862
Orphanet52 ORPHA221117
SNOMED-CT60 36785009
MESH via Orphanet38 D005862
UMLS via Orphanet67 C0017494

Summaries for Gerstmann Syndrome

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NINDS:47 Gerstmann's syndrome is a cognitive impairment that results from damage to a specific area of the brain -- the left parietal lobe in the region of the angular gyrus. It may occur after a stroke or in association with damage to the parietal lobe. It is characterized by four primary symptoms: a writing disability (agraphia or dysgraphia), a lack of understanding of the rules for calculation or arithmetic (acalculia or dyscalculia), an inability to distinguish right from left, and an inability to identify fingers (finger agnosia). The disorder should not be confused with , a type of transmissible spongiform encephalopathy.

MalaCards based summary: Gerstmann Syndrome, also known as developmental gerstmann's syndrome, is related to gitelman syndrome and glutamine deficiency, congenital, and has symptoms including agraphia, acalculia and finger agnosia. An important gene associated with Gerstmann Syndrome is CBS (Cystathionine-Beta-Synthase), and among its related pathways are IL12-mediated signaling events and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include left parietal lobe, parietal lobe and brain.

Disease Ontology:11 A nervous system disease that results from damage located in left parietal lobe, has symptom agraphia, has symptom acalculia, has symptom finger agnosia.

Wikipedia:69 Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms... more...

Related Diseases for Gerstmann Syndrome

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Diseases related to Gerstmann Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 160)
idRelated DiseaseScoreTop Affiliating Genes
1gitelman syndrome11.0
2glutamine deficiency, congenital10.9
3megaloblastic anemia-1, finnish type10.9
4griscelli syndrome10.9
5pseudohypoparathyroidism10.7
6adenoma10.3
7thyroiditis10.2
8neuroblastoma10.1
9glioma10.1
10aphasia10.1
11albright's hereditary osteodystrophy10.1
12pseudohypoparathyroidism ic10.0
13gnas hyperfunction10.0
14ocular hypertension10.0CD4, CD8A
15arteriovenous malformation10.0CD4, CD8A
16meckel's diverticulitis10.0CD4, CD8A
17scrotum squamous cell carcinoma10.0CD4, CD8A
18acute cystitis10.0CD4, CD8A
19folliculitis10.0CD4, CD8A
20cd3gamma deficiency10.0CD4, CD8A
21vaccinia10.0CD4, CD8A
22esophagus carcinoma in situ10.0CD4, CD8A
23keratoconjunctivitis10.0CD4, CD8A
24intestinal disaccharidase deficiency10.0CD4, CD8A
25penis basal cell carcinoma10.0CD4, CD8A
26chronic eosinophilic pneumonia10.0CD4, CD8A
27psoriasis10.0CD4, CD8A
28inhalation anthrax10.0CD4, CD8A
29cholera10.0
30pituitary adenoma10.0
31pituitary tumors10.0
32alzheimer disease10.0
33neurotic excoriation10.0CD4, CD8A
34total internal ophthalmoplegia10.0CD4, CD8A
35soft palate cancer10.0CD4, CD8A
36agammaglobulinemia, microcephaly, and severe dermatitis10.0CD4, CD8A
37malignant eyelid melanoma10.0CD4, CD8A
38scleral disease10.0CD4, CD8A
39conventional leiomyosarcoma10.0CD4, CD8A
40dna ligase iv deficiency10.0CD4, CD8A
41partial third-nerve palsy10.0CD4, CD8A
42complex partial epilepsy10.0CD4, CD8A
43kidney rhabdoid cancer10.0CD4, CD8A
44endometrioid ovary carcinoma10.0CD4, CD8A
45postcricoid region cancer10.0CD4, CD8A
46cauda equina syndrome10.0CD4, CD8A
47pneumonic tularemia10.0CD4, CD8A
48capgras syndrome10.0CD4, CD8A
49yellow fever10.0CD4, CD8A
50alkhurma hemorrhagic fever10.0CD4, CD8A

Graphical network of the top 20 diseases related to Gerstmann Syndrome:



Diseases related to gerstmann syndrome

Symptoms for Gerstmann Syndrome

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Symptoms:

 11
  • agraphia
  • acalculia
  • finger agnosia

UMLS symptoms related to Gerstmann Syndrome:


visual agnosia, other and unspecified symbolic dysfunctions, specific learning problem, neurologic neglect syndrome, cortical dysfunction nec, hemiapraxia, amimia, autoscopy, altered pitch perception, hemiasomatognosia

Drugs & Therapeutics for Gerstmann Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Gerstmann Syndrome


Cochrane evidence based reviews: gerstmann syndrome

Genetic Tests for Gerstmann Syndrome

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Anatomical Context for Gerstmann Syndrome

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MalaCards organs/tissues related to Gerstmann Syndrome:

34
Parietal lobe, Brain

FMA organs/tissues related to Gerstmann Syndrome:

17
Left parietal lobe

Animal Models for Gerstmann Syndrome or affiliated genes

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Publications for Gerstmann Syndrome

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Articles related to Gerstmann Syndrome:

(show all 30)
idTitleAuthorsYear
1
"With a Smile Through Tears": The Uprooted Career of the Man Behind Gerstmann Syndrome. (25259646)
2014
2
Mirror visual feedback for right-left discrimination in a patient with developmental Gerstmann syndrome. (24515713)
2014
3
Developmental Gerstmann syndrome in a young Taiwanese male: a case report. (19540897)
2009
4
A disconnection account of Gerstmann syndrome: functional neuroanatomy evidence. (19938150)
2009
5
Writing, calculating, and finger recognition in the region of the angular gyrus: a cortical stimulation study of Gerstmann syndrome. (14567608)
2003
6
The Gerstmann syndrome in Alzheimer's disease. (11861708)
2002
7
Gerstmann syndrome in systemic lupus erythematosus: neuropsychological, neuroimaging and spectroscopic findings. (11788743)
2001
8
Acetazolamide-induced Gerstmann syndrome. (10692744)
1999
9
A pure case of Gerstmann syndrome with a subangular lesion. (10356063)
1999
10
Toe agnosia in Gerstmann syndrome. (9328265)
1997
11
Left atrial myxoma presenting as Gerstmann syndrome. (8548463)
1996
12
Gerstmann syndrome: a case report. (2249447)
1990
13
Developmental Gerstmann syndrome: case report and review of the literature. (3611364)
1987
14
Gerstmann syndrome without aphasia: a longitudinal study. (6537237)
1984
15
Piagetian theory and the atypical case: an analysis of the developmental Gerstmann syndrome. (7229539)
1981
16
Echoacousia in Gerstmann syndrome. (712970)
1978
17
Dyscalculia and elements of the developmental Gerstmann syndrome in school children. (679700)
1978
18
Disorders of oculomotor scanning and graphic orientation in developmental Gerstmann syndrome. (618563)
1978
19
Reflections on the Gerstmann syndrome. (318903)
1977
20
Gerstmann syndrome without aphasia: a reply to Poeck and Orgass. (1204370)
1975
21
Gerstmann syndrome without aphasia: comments on the paper by Strub and Geschwind. (1204369)
1975
22
Gerstmann syndrome without aphasia. (4452255)
1974
23
Developmental Gerstmann syndrome. (5461058)
1970
24
Some posthumous notes on the Gerstmann syndrome. (4245825)
1970
25
Developmental Gerstmann syndrome. (4174929)
1968
26
The developmental Gerstmann syndrome. (14032921)
1963
27
Neuro-ophthalmic aspects of the Gerstmann syndrome. A case report. (14456348)
1962
28
Some notes on the Gerstmann syndrome. (13483851)
1957
29
An early description of the Gerstmann syndrome. (13378586)
1956
30
The Gerstmann syndrome; case report and review of the literature. (20291825)
1947

Variations for Gerstmann Syndrome

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Expression for genes affiliated with Gerstmann Syndrome

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Search GEO for disease gene expression data for Gerstmann Syndrome.

Pathways for genes affiliated with Gerstmann Syndrome

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GO Terms for genes affiliated with Gerstmann Syndrome

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Cellular components related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1T cell receptor complexGO:00421019.5CD4, CD8A
2external side of plasma membraneGO:00098979.1CD4, CD8A

Biological processes related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1positive regulation of calcium-mediated signalingGO:00508509.5CD4, CD8A
2transmembrane receptor protein tyrosine kinase signaling pathwayGO:00071699.1CD4, CD8A
3T cell activationGO:00421109.0CD4, CD8A

Molecular functions related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1coreceptor activityGO:00150269.5CD4, CD8A
2protein homodimerization activityGO:00428038.5CBS, CD4, CD8A

Sources for Gerstmann Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet