GS
MCID: GRS001
MIFTS: 36

Gerstmann Syndrome (GS) malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Gerstmann Syndrome

Aliases & Descriptions for Gerstmann Syndrome:

Name: Gerstmann Syndrome 12 50 56 42 14 69
Developmental Gerstmann's Syndrome 69
Developmental Gerstmann Syndrome 50
Aphasia-Angular Gyrus Syndrome 12
Gerstmann Badal Syndrome 50
Gerstmann's Syndrome 51
Gerstmann Tetrad 50
Gs 50

Classifications:

Orphanet: 56  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4969
MeSH 42 D005862
SNOMED-CT 64 36785009
Orphanet 56 ORPHA221117
ICD10 via Orphanet 34 F81.2
MESH via Orphanet 43 D005862
UMLS via Orphanet 70 C0017494
UMLS 69 C0017494

Summaries for Gerstmann Syndrome

NINDS : 51 Gerstmann's syndrome is a cognitive impairment that results from damage to a specific area of the brain -- the left parietal lobe in the region of the angular gyrus. It may occur after a stroke or in association with damage to the parietal lobe. It is characterized by four primary symptoms: a writing disability (agraphia or dysgraphia), a lack of understanding of the rules for calculation or arithmetic (acalculia or dyscalculia), an inability to distinguish right from left, and an inability to identify fingers (finger agnosia). The disorder should not be confused with , a type of transmissible spongiform encephalopathy.

MalaCards based summary : Gerstmann Syndrome, also known as developmental gerstmann's syndrome, is related to pseudohypoparathyroidism and pseudohypoparathyroidism ic, and has symptoms including agraphia, acalculia and finger agnosia. An important gene associated with Gerstmann Syndrome is CBS (Cystathionine-Beta-Synthase), and among its related pathways/superpathways are T cell receptor signaling pathway and Cell adhesion molecules (CAMs). Affiliated tissues include brain, parietal lobe and left parietal lobe.

Disease Ontology : 12 A nervous system disease that results_from damage located in left parietal lobe, has symptom agraphia, has symptom acalculia, has symptom finger agnosia.

Wikipedia : 71 Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms... more...

Related Diseases for Gerstmann Syndrome

Diseases related to Gerstmann Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 134)
id Related Disease Score Top Affiliating Genes
1 pseudohypoparathyroidism 11.1
2 pseudohypoparathyroidism ic 10.9
3 gnas hyperfunction 10.9
4 finger agnosia 10.8
5 glutamine deficiency, congenital 10.8
6 megaloblastic anemia-1, finnish type 10.8
7 gitelman syndrome 10.8
8 griscelli syndrome 10.8
9 mccune-albright syndrome, somatic, mosaic 10.8
10 pseudohypoparathyroidism, type ib 10.8
11 gilbert syndrome 10.8
12 adenoma 10.1
13 thyroiditis 10.1
14 orbital disease 10.0 CD4 CD8A
15 colloid adenoma 10.0 CD4 CD8A
16 retinal microaneurysm 10.0 CD4 CD8A
17 scrotum melanoma 10.0 CD4 CD8A
18 cervix melanoma 10.0 CD4 CD8A
19 coronin-1a deficiency 10.0 CD4 CD8A
20 scrotum squamous cell carcinoma 10.0 CD4 CD8A
21 eczema herpeticum 10.0 CD4 CD8A
22 infundibulocystic basal cell carcinoma 10.0 CD4 CD8A
23 mixed germ cell cancer 10.0 CD4 CD8A
24 plasmacytic leukemia 10.0 CD4 CD8A
25 vestibule of mouth cancer 10.0 CD4 CD8A
26 autoimmune polyendocrine syndrome type 1 10.0 CD4 CD8A
27 neuropathy, hereditary thermosensitive 10.0 CD4 CD8A
28 non-suppurative otitis media 10.0 CD4 CD8A
29 human immunodeficiency virus infectious disease 10.0 CD4 CD8A
30 lambda 5 deficiency 10.0 CD4 CD8A
31 cerebrum cancer 10.0 CD4 CD8A
32 herpetic whitlow 10.0 CD4 CD8A
33 dysentery 10.0 CD4 CD8A
34 dysplastic nevus syndrome 10.0 CD4 CD8A
35 extragonadal seminoma 10.0 CD4 CD8A
36 abducens nerve disease 10.0 CD4 CD8A
37 allergic conjunctivitis 10.0 CD4 CD8A
38 congenital hypothyroidism 10.0 CD4 CD8A
39 neuroblastoma 10.0
40 glioma 10.0
41 perinatal necrotizing enterocolitis 10.0 CD4 CD8A
42 sensory organ benign neoplasm 10.0 CD4 CD8A
43 pneumoconiosis 10.0 CD4 CD8A
44 bladder diverticulum 10.0 CD4 CD8A
45 phlyctenulosis 10.0 CD4 CD8A
46 rectum lymphoma 10.0 CD4 CD8A
47 tularemia 10.0 CD4 CD8A
48 rosacea conjunctivitis 10.0 CD4 CD8A
49 gluten allergy 10.0 CD4 CD8A
50 oral cavity cancer 10.0 CD4 CD8A

Graphical network of the top 20 diseases related to Gerstmann Syndrome:



Diseases related to Gerstmann Syndrome

Symptoms & Phenotypes for Gerstmann Syndrome

Symptoms:

12
  • agraphia
  • acalculia
  • finger agnosia

UMLS symptoms related to Gerstmann Syndrome:


other symbolic dysfunction

Drugs & Therapeutics for Gerstmann Syndrome

Search Clinical Trials , NIH Clinical Center for Gerstmann Syndrome

Cochrane evidence based reviews: gerstmann syndrome

Genetic Tests for Gerstmann Syndrome

Anatomical Context for Gerstmann Syndrome

MalaCards organs/tissues related to Gerstmann Syndrome:

39
Brain, Parietal Lobe

The Foundational Model of Anatomy Ontology organs/tissues related to Gerstmann Syndrome:

18
Left Parietal Lobe

Publications for Gerstmann Syndrome

Articles related to Gerstmann Syndrome:

(show all 30)
id Title Authors Year
1
"With a Smile Through Tears": The Uprooted Career of the Man Behind Gerstmann Syndrome. ( 25259646 )
2014
2
Mirror visual feedback for right-left discrimination in a patient with developmental Gerstmann syndrome. ( 24515713 )
2014
3
A disconnection account of Gerstmann syndrome: functional neuroanatomy evidence. ( 19938150 )
2009
4
Developmental Gerstmann syndrome in a young Taiwanese male: a case report. ( 19540897 )
2009
5
Writing, calculating, and finger recognition in the region of the angular gyrus: a cortical stimulation study of Gerstmann syndrome. ( 14567608 )
2003
6
The Gerstmann syndrome in Alzheimer's disease. ( 11861708 )
2002
7
Gerstmann syndrome in systemic lupus erythematosus: neuropsychological, neuroimaging and spectroscopic findings. ( 11788743 )
2001
8
A pure case of Gerstmann syndrome with a subangular lesion. ( 10356063 )
1999
9
Acetazolamide-induced Gerstmann syndrome. ( 10692744 )
1999
10
Toe agnosia in Gerstmann syndrome. ( 9328265 )
1997
11
Left atrial myxoma presenting as Gerstmann syndrome. ( 8548463 )
1996
12
Gerstmann syndrome: a case report. ( 2249447 )
1990
13
Developmental Gerstmann syndrome: case report and review of the literature. ( 3611364 )
1987
14
Gerstmann syndrome without aphasia: a longitudinal study. ( 6537237 )
1984
15
Piagetian theory and the atypical case: an analysis of the developmental Gerstmann syndrome. ( 7229539 )
1981
16
Echoacousia in Gerstmann syndrome. ( 712970 )
1978
17
Dyscalculia and elements of the developmental Gerstmann syndrome in school children. ( 679700 )
1978
18
Disorders of oculomotor scanning and graphic orientation in developmental Gerstmann syndrome. ( 618563 )
1978
19
Reflections on the Gerstmann syndrome. ( 318903 )
1977
20
Gerstmann syndrome without aphasia: comments on the paper by Strub and Geschwind. ( 1204369 )
1975
21
Gerstmann syndrome without aphasia: a reply to Poeck and Orgass. ( 1204370 )
1975
22
Gerstmann syndrome without aphasia. ( 4452255 )
1974
23
Some posthumous notes on the Gerstmann syndrome. ( 4245825 )
1970
24
Developmental Gerstmann syndrome. ( 5461058 )
1970
25
Developmental Gerstmann syndrome. ( 4174929 )
1968
26
The developmental Gerstmann syndrome. ( 14032921 )
1963
27
Neuro-ophthalmic aspects of the Gerstmann syndrome. A case report. ( 14456348 )
1962
28
Some notes on the Gerstmann syndrome. ( 13483851 )
1957
29
An early description of the Gerstmann syndrome. ( 13378586 )
1956
30
The Gerstmann syndrome; case report and review of the literature. ( 20291825 )
1947

Variations for Gerstmann Syndrome

Expression for Gerstmann Syndrome

Search GEO for disease gene expression data for Gerstmann Syndrome.

Pathways for Gerstmann Syndrome

GO Terms for Gerstmann Syndrome

Cellular components related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 external side of plasma membrane GO:0009897 8.96 CD4 CD8A
2 T cell receptor complex GO:0042101 8.62 CD4 CD8A

Biological processes related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cell surface receptor signaling pathway GO:0007166 9.26 CD4 CD8A
2 transmembrane receptor protein tyrosine kinase signaling pathway GO:0007169 9.16 CD4 CD8A
3 T cell activation GO:0042110 8.96 CD4 CD8A
4 positive regulation of calcium-mediated signaling GO:0050850 8.62 CD4 CD8A

Molecular functions related to Gerstmann Syndrome according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.13 CBS CD4 CD8A
2 coreceptor activity GO:0015026 8.62 CD4 CD8A

Sources for Gerstmann Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....