MCID: GRS001
MIFTS: 28

Gerstmann Syndrome malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Gerstmann Syndrome

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 46NINDS, 59SNOMED-CT, 37MESH via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Gerstmann Syndrome:

Name: Gerstmann Syndrome 10 45 12 51 36 65
Developmental Gerstmann's Syndrome 65
Developmental Gerstmann Syndrome 45
Aphasia-Angular Gyrus Syndrome 10
 
Gerstmann Badal Syndrome 45
Gerstmann's Syndrome 46
Gerstmann Tetrad 45
Gs 45

Classifications:



External Ids:

Disease Ontology10 DOID:4969
MeSH36 D005862
Orphanet51 221117
SNOMED-CT59 36785009
MESH via Orphanet37 D005862
UMLS via Orphanet66 C0017494
UMLS65 C0017494, C0936244

Summaries for Gerstmann Syndrome

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NINDS:46 Gerstmann's syndrome is a cognitive impairment that results from damage to a specific area of the brain -- the left parietal lobe in the region of the angular gyrus. It may occur after a stroke or in association with damage to the parietal lobe. It is characterized by four primary symptoms: a writing disability (agraphia or dysgraphia), a lack of understanding of the rules for calculation or arithmetic (acalculia or dyscalculia), an inability to distinguish right from left, and an inability to identify fingers (finger agnosia). The disorder should not be confused with , a type of transmissible spongiform encephalopathy.

MalaCards based summary: Gerstmann Syndrome, also known as developmental gerstmann's syndrome, is related to gitelman syndrome and megaloblastic anemia-1, finnish type, and has symptoms including agraphia, acalculia and finger agnosia. An important gene associated with Gerstmann Syndrome is TBX1 (T-Box 1). Affiliated tissues include left parietal lobe, parietal lobe and brain.

Disease Ontology:10 A nervous system disease that results from damage located in left parietal lobe, has symptom agraphia, has symptom acalculia, has symptom finger agnosia.

Wikipedia:68 Gerstmann syndrome is a neuropsychological disorder that is characterized by a constellation of symptoms... more...

Related Diseases for Gerstmann Syndrome

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Graphical network of the top 20 diseases related to Gerstmann Syndrome:



Diseases related to gerstmann syndrome

Symptoms for Gerstmann Syndrome

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Symptoms:

 10
  • agraphia
  • acalculia
  • finger agnosia

Drugs & Therapeutics for Gerstmann Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Gerstmann Syndrome


Cochrane evidence based reviews: gerstmann syndrome

Genetic Tests for Gerstmann Syndrome

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Anatomical Context for Gerstmann Syndrome

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MalaCards organs/tissues related to Gerstmann Syndrome:

33
Parietal lobe, Brain, Breast, T cells, B cells, Eye

FMA organs/tissues related to Gerstmann Syndrome:

16
Left parietal lobe

Animal Models for Gerstmann Syndrome or affiliated genes

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Publications for Gerstmann Syndrome

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Articles related to Gerstmann Syndrome:

(show all 30)
idTitleAuthorsYear
1
CD19 chimeric antigen receptor T cell therapy for the treatment of B cell lineage acute lymphoblastic leukemia. (26562471)
2015
2
cMET in triple-negative breast cancer: is it a therapeutic target for this subset of breast cancer patients? (25084805)
2014
3
Clues to diagnosis of connubial contact dermatitis to paraphenylenediamine. (24407061)
2014
4
Construction and analysis of multiparameter prognostic models for melanoma outcome. (24258982)
2014
5
Interaction of serotonin transporter linked polymorphic region and childhood neglect on criminal behavior and substance use for males and females. (22293003)
2012
6
Genome-wide association analysis of genetic generalized epilepsies implicates susceptibility loci at 1q43, 2p16.1, 2q22.3 and 17q21.32. (22949513)
2012
7
Clinical results of topography-based customized ablations in highly aberrated eyes and keratoconus/ectasia with cross-linking. (23447899)
2012
8
Antibodies against extracellular domains of I+4 and I+7 subunits alter the levels of nicotinic receptors in the mouse brain and affect memory: possible relevance to Alzheimer's pathology. (21321393)
2011
9
Atheroprotective reverse cholesterol transport pathway is defective in familial hypercholesterolemia. (21527752)
2011
10
The effectiveness and feasibility of endovascular coil embolization for very small cerebral aneurysms: mid- and long-term follow-up. (20036498)
2010
11
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5. (20038797)
2010
12
Interleukin-33 prevents apoptosis and improves survival after experimental myocardial infarction through ST2 signaling. (19919994)
2009
13
Raf inhibition protects cortical cells against beta-amyloid toxicity. (18706973)
2008
14
Effect of antibodies on the expression of Plasmodium falciparum circumsporozoite protein gene. (16421624)
2006
15
The peptidic urotensin-II receptor ligand GSK248451 possesses less intrinsic activity than the low-efficacy partial agonists SB-710411 and urantide in native mammalian tissues and recombinant cell systems. (16547525)
2006
16
Identification of a novel human immunodeficiency virus type 1 integrase interactor, Gemin2, that facilitates efficient viral cDNA synthesis in vivo. (16731905)
2006
17
Mutant P450 oxidoreductase causes disordered steroidogenesis with and without Antley-Bixler syndrome. (14758361)
2004
18
Iron-sulfur protein maturation in human cells: evidence for a function of frataxin. (15509595)
2004
19
Cell cycle control: a complex issue. (14726706)
2004
20
Gluthathion synthetase deficit in a newborn infant]. (15519833)
2004
21
Are milk polyamines preventive agents against food allergy? (10828177)
2000
22
Augmentation of pulmonary host defense against Pseudomonas by FcgammaRIIA cDNA transfer to the respiratory epithelium. (10449433)
1999
23
Resuming translation on tmRNA: a unique mode of determining a reading frame. (10508174)
1999
24
A novel method for chemical modification of functional groups other than a carboxyl group in proteins by N-ethyl-5-phenylisooxazolium-3'-sulfonate (Woodward's reagent-K): inhibition of ADP-induced platelet responses involves covalent modification of aggregin, an ADP receptor. (8811919)
1996
25
Human adenosine A2a receptor (A2aAR) gene: systematic mutation screening in patients with schizophrenia. (9029412)
1996
26
Specificity studies of 3-Mercaptopyruvate sulfurtransferase. (8934630)
1995
27
Fibrinogen anomalies and disease. A clinical update. (1400080)
1992
28
Thiamin and the brain. (3060175)
1988
29
Structural identity of Bence Jones and amyloid fibril proteins in a patient with plasma cell dyscrasia and amyloidosis. (4700495)
1973
30
Report on 280 cases of verified parasagittal meningioma. (13272053)
1955

Variations for Gerstmann Syndrome

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Expression for genes affiliated with Gerstmann Syndrome

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Search GEO for disease gene expression data for Gerstmann Syndrome.

Pathways for genes affiliated with Gerstmann Syndrome

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GO Terms for genes affiliated with Gerstmann Syndrome

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Sources for Gerstmann Syndrome

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet