MCID: GST052
MIFTS: 38

Gestational Choriocarcinoma malady

Reproductive diseases, Cancer diseases categories

Summaries for Gestational Choriocarcinoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event... more...

MalaCards: Gestational Choriocarcinoma, also known as molar pregnancy with choriocarcinoma, is related to choriocarcinoma and hypertension. An important gene associated with Gestational Choriocarcinoma is IFNG (interferon, gamma). The compounds oestriol and ctp have been mentioned in the context of this disorder. Affiliated tissues include ovary, placenta and liver.

Aliases & Classifications for Gestational Choriocarcinoma

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Sources:
8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 39NCIt, 57SNOMED-CT via Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Reproductive diseases


Characteristics (Orphanet epidemiological data):

48
gestational choriocarcinoma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

gestational choriocarcinoma 8 10 48 60
molar pregnancy with choriocarcinoma 8
gestational chorionepithelioma 8


External Ids:

Disease Ontology8 DOID:2025
NCIt39 C4646
SNOMED-CT via Orphanet57 417570003, 417057000
ICD10 via Orphanet26 C58

Related Diseases for Gestational Choriocarcinoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Gestational Choriocarcinoma:



Diseases related to gestational choriocarcinoma

Clinical Features for Gestational Choriocarcinoma

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Drugs & Therapeutics for Gestational Choriocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

Search ClinicalTrials for Gestational Choriocarcinoma

Search NIH Clinical Center for Gestational Choriocarcinoma

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Genetic Tests for Gestational Choriocarcinoma

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Anatomical Context for Gestational Choriocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Gestational Choriocarcinoma:

32
Ovary, Placenta, Liver, Cervix, Brain, Uterus, Small intestine, Lung

Animal Models for Gestational Choriocarcinoma or affiliated genes

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Publications for Gestational Choriocarcinoma

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50PubMed
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Articles related to Gestational Choriocarcinoma:

(show top 50)    (show all 152)
idTitleAuthorsYear
1
Gestational choriocarcinoma in liver mimicking ruptured ectopic pregnancy. (22663336)
2012
2
Gestational choriocarcinoma arising in a tubal ectopic pregnancy: case report. (22053686)
2011
3
Cerebral venous sinus thrombosis presenting as cerebral metastasis in a patient with choriocarcinoma following a non-molar gestation. (21514630)
2011
4
Gestational choriocarcinoma transmission following multiorgan donation. (20977645)
2010
5
Gestational choriocarcinoma presenting as hemothorax. (22842324)
2010
6
Gestational choriocarcinoma diagnosed with spontaneous splenic rupture after pregnancy induced by in vitro fertilization: a case report. (19829989)
2009
7
Non-gestational uterine choriocarcinoma in a postmenopausal woman. (19556820)
2009
8
Uterine gestational choriocarcinoma developing after a long latent period in a postmenopausal woman: the value of DNA polymorphism studies. (18417687)
2008
9
Hyperglycosylated hCG in gestational implantation and in choriocarcinoma and testicular germ cell malignancy tumorigenesis. (17165440)
2006
10
Pure non-gestational choriocarcinoma of the ovary diagnosed by DNA polymorphism analysis. (16984618)
2006
11
Treatment of metastatic gestational choriocarcinoma with oral methotrexate in a combat environment. (15863599)
2005
12
An unusual gestational choriocarcinoma occurring primarily on the surface of a subserous leiomyoma. (14723763)
2004
13
Gestational choriocarcinoma: an unusual presentation with response to gemcitabine and surgery. (15008778)
2004
14
Trends in gestational choriocarcinoma: a 27-year perspective. (14672473)
2003
15
Prognosis of gestational choriocarcinoma at Khyber Teaching Hospital Peshawar. (14552249)
2003
16
Primary abdominal gestational choriocarcinoma. (14672474)
2003
17
Complete remission of gestational choriocarcinoma with choroidal metastasis treated with systemic chemotherapy alone: case report and review of literature. (11733980)
2001
18
Gestational choriocarcinoma arising in a cornual pregnancy. (11311774)
2001
19
Activity of docetaxel in chemoresistant gestational choriocarcinoma. (11104635)
2000
20
High hCG level is a risk factor for predicting the occurrence of brain and/or liver metastases from gestational choriocarcinoma. (10390104)
1999
21
Postpartal gestational choriocarcinoma fatally misdiagnosed as squamous cell cancer of the uterine cervix. (9443576)
1997
22
Gestational choriocarcinoma metastatic to the brain treated successfully by stereotactic radiosurgery and chemotherapy. (8871007)
1996
23
An extra gonadal non-gestational choriocarcinoma in a woman treated for an endometrial carcinoma. (7543866)
1995
24
Pure choriocarcinoma of ovary, probably non-gestational in origin. (7781102)
1995
25
Gestational choriocarcinoma in norway, 1953-92 - an epidemiologic report. (21573475)
1993
26
Another case of metastatic gestational choriocarcinoma arising from a primary fallopian tube ectopic pregnancy. (8382441)
1993
27
Gestational choriocarcinoma in a tubal ectopic pregnancy. (1315103)
1992
28
Interferon-gamma receptors on human gestational choriocarcinoma cell lines: quantitative and functional studies. (1386713)
1992
29
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. (1868436)
1991
30
Gestational choriocarcinoma with haemorrhagic pleural effusion. (1724229)
1991
31
Ultrasonic morphology of the uterus and ovaries after treatment of invasive mole and gestational choriocarcinoma. (2176560)
1990
32
Establishment and characterization of a subline predisposed to pulmonary metastasis from a human gestational choriocarcinoma cell line in nude mice. (2520787)
1989
33
Pulmonary hypertension in gestational choriocarcinoma: a west London syndrome? (2899699)
1988
34
Radioimmunoscintigraphic detection of occult gestational choriocarcinoma. (2432784)
1987
35
Studies on antilymphocyte antibodies in gestational choriocarcinoma. (2950130)
1986
36
An immunohistological study of HLA antigen expression by gestational choriocarcinoma. (2408648)
1985
37
VP-16 in combinations for first-line treatment of malignant germ-cell tumors and gestational choriocarcinoma. (2579442)
1985
38
Pitfalls in the diagnosis of gestational choriocarcinoma. A case report. (6538051)
1984
39
Role of thoracotomy in pulmonary metastases from gestational choriocarcinoma. (6682918)
1983
40
A newly established human gestational choriocarcinoma cell line and its characterization. (6190712)
1983
41
Gestational choriocarcinoma. Its origin in the placenta during seemingly normal pregnancy. (7235120)
1981
42
Pulmonary resection in the management of metastases from gestational choriocarcinoma. (7194950)
1981
43
Histologic stromal reaction of the host with gestational choriocarcinoma and its relation to clinical stage classification and prognosis. (7258260)
1981
44
Anti-tumour activity of the epipodophyllin derivative VP16-213 (etoposide: NSC-141540) in gestational choriocarcinoma. (6154579)
1980
45
Gestational choriocarcinoma and thyrotoxicosis. (455255)
1979
46
Activity of high-dose cis-platinum (NCI 119875) in combination with vincristine and methotrexate in drug-resistant gestational choriocarcinoma. A report of 17 cases. (575049)
1979
47
The role of thoracotomy in the management of the pulmonary metastases of gestational choriocarcinoma. (1212836)
1975
48
Invasive mole, gestational choriocarcinoma and transplantation antigens. (4364364)
1972
49
Gestational choriocarcinoma in Denmark 1940-1969. A reappraisal based on modern histologic criteria. (4340330)
1972
50
Histocompatibility antigens on the HL-A locus in gestational choriocarcinoma. (5406845)
1969

Genetic Variations for Gestational Choriocarcinoma

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Expression for genes affiliated with Gestational Choriocarcinoma

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gestational Choriocarcinoma

Search GEO for disease gene expression data for Gestational Choriocarcinoma.

Pathways for genes affiliated with Gestational Choriocarcinoma

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Compounds for genes affiliated with Gestational Choriocarcinoma

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44Novoseek, 24HMDB
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Compounds related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oestriol4410.0CGB7, CGB5
2ctp449.9CGB5, CGB7
3indoleamine449.9CGB5, IFNG
47,8-dihydroneopterin44 2410.5ALPP, IFNG
5zoledronic acid449.4ALPP, IFNG
6aphidicolin449.3IFNG, ALPP
7arginine448.6ALPP, ENPEP, CGB5, IFNG
8vegf448.3ALPP, ENPEP, CGB5, IFNG

GO Terms for genes affiliated with Gestational Choriocarcinoma

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Products for genes affiliated with Gestational Choriocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gestational Choriocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet