MCID: GST052
MIFTS: 40

Gestational Choriocarcinoma malady

Reproductive diseases, Cancer diseases, Rare diseases categories
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Summaries for Gestational Choriocarcinoma

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65Wikipedia, 33MalaCards
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Wikipedia:65 Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event... more...

MalaCards: Gestational Choriocarcinoma, also known as molar pregnancy with choriocarcinoma, is related to choriocarcinoma and ectopic pregnancy. An important gene associated with Gestational Choriocarcinoma is IFNG (interferon, gamma), and among its related pathways is Peptide hormone metabolism. The compounds indoleamine and oestriol have been mentioned in the context of this disorder. Affiliated tissues include ovary, placenta and liver.

Aliases & Classifications for Gestational Choriocarcinoma

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8Disease Ontology, 10DISEASES, 49Orphanet, 62UMLS, 40NCIt, 58SNOMED-CT, 59SNOMED-CT via Orphanet, 63UMLS via Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Reproductive diseases


Characteristics (Orphanet epidemiological data):

49
gestational choriocarcinoma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

gestational choriocarcinoma 8 10 49 62
molar pregnancy with choriocarcinoma 8
gestational chorionepithelioma 8


External Ids:

Disease Ontology8 DOID:2025
NCIt40 C4646
SNOMED-CT via Orphanet59 417570003, 417057000
UMLS via Orphanet63 C0349557
ICD10 via Orphanet26 C58

Related Diseases for Gestational Choriocarcinoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Gestational Choriocarcinoma:



Diseases related to gestational choriocarcinoma

Symptoms for Gestational Choriocarcinoma

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Drugs & Therapeutics for Gestational Choriocarcinoma

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

Search ClinicalTrials for Gestational Choriocarcinoma

Search NIH Clinical Center for Gestational Choriocarcinoma

Genetic Tests for Gestational Choriocarcinoma

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Anatomical Context for Gestational Choriocarcinoma

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33MalaCards
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MalaCards organs/tissues related to Gestational Choriocarcinoma:

33
Ovary, Placenta, Liver, Cervix, Brain, Uterus, Small intestine, Lung

Animal Models for Gestational Choriocarcinoma or affiliated genes

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Publications for Gestational Choriocarcinoma

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52PubMed
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Articles related to Gestational Choriocarcinoma:

(show top 50)    (show all 138)
idTitleAuthorsYear
1
Glycan profiling of gestational choriocarcinoma using a lectin microarray. (24424471)
2014
2
Coexistent gestational choriocarcinoma and mixed adenocarcinoma of the uterus. (24020150)
2013
3
Gestational choriocarcinoma in the fallopian tube. (24219747)
2013
4
Clinical Outcome of a FIGO Stage IV Gestational Choriocarcinoma. (24163669)
2013
5
An unusual cause of lower GI bleeding in a young woman: metastatic gestational choriocarcinoma. (22421497)
2013
6
Subcutaneous mass as the primary manifestation of gestational choriocarcinoma: A case report. (24371601)
2011
7
Gestational choriocarcinoma arising in a tubal ectopic pregnancy: case report. (22053686)
2011
8
Gestational choriocarcinoma of Fallopian tube diagnosed with a combination of p57KIP2 immunostaining and short tandem repeat analysis: case report. (21599798)
2011
9
Gestational choriocarcinoma in one placenta of dichorionic diamniotic twins who showed severe anemia. (19608272)
2009
10
Acute abdomen as initial presentation of gestational choriocarcinoma. (19288267)
2009
11
Gestational choriocarcinoma: morphological features in a liquid-based endometrial cytological sample. (18181184)
2008
12
Gestational choriocarcinoma arising from a cornual ectopic pregnancy: a case report and review of the literature. (17581760)
2007
13
Pure non-gestational choriocarcinoma of the ovary diagnosed by DNA polymorphism analysis. (16984618)
2006
14
An unusual gestational choriocarcinoma occurring primarily on the surface of a subserous leiomyoma. (14723763)
2004
15
Gestational choriocarcinoma: an unusual presentation with response to gemcitabine and surgery. (15008778)
2004
16
Activity of docetaxel in chemoresistant gestational choriocarcinoma. (11104635)
2000
17
A case of metastatic ovarian non-gestational choriocarcinoma: successful treatment with conservative type surgery and myeloablative chemotherapy. (10986872)
2000
18
Gestational choriocarcinoma whose responsible pregnancy was a complete hydatidiform mole identified by PCR analysis with new sequence tagged site primers. (10645807)
1999
19
Gestational choriocarcinoma. (9443570)
1997
20
Postpartal gestational choriocarcinoma fatally misdiagnosed as squamous cell cancer of the uterine cervix. (9443576)
1997
21
Gestational choriocarcinoma metastatic to the brain treated successfully by stereotactic radiosurgery and chemotherapy. (8871007)
1996
22
An extra gonadal non-gestational choriocarcinoma in a woman treated for an endometrial carcinoma. (7543866)
1995
23
Thoracotomy in the management of gestational choriocarcinoma. A clinicopathologic study. (8374875)
1993
24
Gestational choriocarcinoma in norway, 1953-92 - an epidemiologic report. (21573475)
1993
25
Another case of metastatic gestational choriocarcinoma arising from a primary fallopian tube ectopic pregnancy. (8382441)
1993
26
Documentation of complete resolution of gestational choriocarcinoma in the oophorectomized patient. (8276305)
1993
27
Gestational choriocarcinoma in a tubal ectopic pregnancy. (1315103)
1992
28
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. (1868436)
1991
29
Metastatic gestational choriocarcinoma. Unusual pathologic variant following therapy. (2465817)
1989
30
Establishment and characterization of three new human gestational choriocarcinoma cell lines. (3171272)
1988
31
Gestational choriocarcinoma presenting as endobronchial carcinoma. (3194870)
1988
32
Expression of HLA-DR molecules in human gestational choriocarcinoma cell lines and malignant cell lines. (3658923)
1987
33
Radioimmunoscintigraphic detection of occult gestational choriocarcinoma. (2432784)
1987
34
An immunohistological study of HLA antigen expression by gestational choriocarcinoma. (2408648)
1985
35
Neoplastic cerebral aneurysm from metastatic gestational choriocarcinoma. Case report. (4040960)
1985
36
Clinical analysis of intracranial metastases in gestational choriocarcinoma: a series of 15 cases. (3862401)
1985
37
Resistant gestational choriocarcinoma: successful treatment with vinblastine, bleomycin, and cisplatin (VBP). (6189602)
1983
38
The role of VP16-213 (etoposide; NSC-141540) in gestational choriocarcinoma. (7083462)
1982
39
Fatal gestational choriocarcinoma. Clinicopathologic study of patients treated at a trophoblastic disease center. (7116308)
1982
40
Gestational choriocarcinoma. Its origin in the placenta during seemingly normal pregnancy. (7235120)
1981
41
The role of thoracotomy in the management of the pulmonary metastases of gestational choriocarcinoma. (1212836)
1975
42
Gestational choriocarcinoma of the tube and ovary. (4730067)
1973
43
Invasive mole and gestational choriocarcinoma in Denmark, 1940-1969. Biological and clinical aspects. (4355252)
1973
44
Chemotherapy of gestational choriocarcinoma. (4641760)
1972
45
Gestational choriocarcinoma. (5065688)
1972
46
Invasive mole, gestational choriocarcinoma and transplantation antigens. (4364364)
1972
47
Chemotherapy of gestational choriocarcinoma: a preliminary report of eight patients treated with methotrexate. (5168900)
1971
48
Extrauterine gestational choriocarcinoma. Report of two cases. (5441265)
1970
49
Histocompatibility antigens on the HL-A locus in gestational choriocarcinoma. (5406845)
1969
50
Gestational choriocarcinoma in the General Hospital of Mexico. Analysis of forty cases. (5659418)
1968

Variations for Gestational Choriocarcinoma

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Expression for genes affiliated with Gestational Choriocarcinoma

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gestational Choriocarcinoma

Search GEO for disease gene expression data for Gestational Choriocarcinoma.

Pathways for genes affiliated with Gestational Choriocarcinoma

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50PathCards, 55Reactome, 38NCBI BioSystems Database
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Pathways related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4CGB5, ENPEP

Compounds for genes affiliated with Gestational Choriocarcinoma

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Sources:
45Novoseek, 24HMDB, 11DrugBank, 51PharmGKB, 29IUPHAR, 3BitterDB, 61Tocris Bioscience
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Compounds related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1indoleamine4510.1IFNG, CGB5
2oestriol4510.1CGB5, CGB7
3ctp4510.1CGB7, CGB5
4l-nmma4510.1CGB5, IFNG
57,8-dihydroneopterin45 2411.0ALPP, IFNG
6zoledronic acid4510.0IFNG, ALPP
7aphidicolin4510.0ALPP, IFNG
8bleomycin45 1110.9CGB5, CGB7
9pge1459.8ALPP, CGB5
10progestin459.8CGB5, ALPP
11hydroxyurea45 51 1111.8CGB5, ALPP
12prednisolone45 29 1111.8ALPP, IFNG
13sodium dodecylsulfate459.7CGB5, ALPP
14hydrocortisone45 3 61 1112.7IFNG, ALPP
15succinate459.6ALPP, ENPEP
16thyroxine45 2410.6CGB7, ALPP
17nifedipine45 29 51 1112.5CGB5, ALPP
18genistein45 29 61 3 24 1114.5CGB5, ALPP, IFNG
19cyclosporin a45 29 6111.5IFNG, ALPP, CGB5
20pge2459.5CGB5, ALPP, IFNG
21lactate459.5ALPP, CGB7, CGB5
22cycloheximide459.5CGB5, ALPP, IFNG
23cisplatin45 51 61 1112.5CGB5, CGB7, ALPP
24ibmx45 61 2911.4CGB5, ALPP
25testosterone45 61 24 1112.4ALPP, CGB7, CGB5
26dexamethasone45 51 29 1112.3CGB5, ALPP, IFNG
27simvastatin45 51 61 29 24 1114.3ALPP, IFNG
28retinoic acid45 2410.2IFNG, ALPP, CGB7, CGB5
29vegf459.0CGB5, ENPEP, ALPP, IFNG
30arginine458.9CGB5, ENPEP, ALPP, IFNG

GO Terms for genes affiliated with Gestational Choriocarcinoma

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Products for genes affiliated with Gestational Choriocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gestational Choriocarcinoma

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet