MCID: GST052
MIFTS: 40

Gestational Choriocarcinoma malady

Reproductive diseases, Cancer diseases, Rare diseases categories
Download this MalaCard

Summaries for Gestational Choriocarcinoma

About this section


Fully expand this MalaCard
Wikipedia:65 Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event... more...

MalaCards based summary: Gestational Choriocarcinoma, also known as molar pregnancy with choriocarcinoma, is related to choriocarcinoma and ectopic pregnancy. An important gene associated with Gestational Choriocarcinoma is IFNG (interferon, gamma), and among its related pathways is Peptide hormone metabolism. The compounds indoleamine and oestriol have been mentioned in the context of this disorder. Affiliated tissues include ovary, placenta and cervix.

Aliases & Classifications for Gestational Choriocarcinoma

About this section
Sources:
8Disease Ontology, 10DISEASES, 48Orphanet, 62UMLS, 57SNOMED-CT, 39NCIt, 26ICD10 via Orphanet, 63UMLS via Orphanet
See all sources

Gestational Choriocarcinoma, Aliases & Descriptions:

Name: Gestational Choriocarcinoma 8 10 48 62
Molar Pregnancy with Choriocarcinoma 8 62
 
Gestational Chorionepithelioma 8 62


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases, Rare diseases
Anatomical: Reproductive diseases


Characteristics (Orphanet epidemiological data):

48
gestational choriocarcinoma:
Inheritance: Sporadic; Age of onset: Adulthood


External Ids:

Disease Ontology8 DOID:2025
NCIt39 C4646
ICD10 via Orphanet26 C58
UMLS via Orphanet63 C0349557

Related Diseases for Gestational Choriocarcinoma

About this section

Graphical network of the top 20 diseases related to Gestational Choriocarcinoma:



Diseases related to gestational choriocarcinoma

Symptoms for Gestational Choriocarcinoma

About this section

Drugs & Therapeutics for Gestational Choriocarcinoma

About this section

Drug clinical trials:

Search ClinicalTrials for Gestational Choriocarcinoma

Search NIH Clinical Center for Gestational Choriocarcinoma

Genetic Tests for Gestational Choriocarcinoma

About this section

Anatomical Context for Gestational Choriocarcinoma

About this section

MalaCards organs/tissues related to Gestational Choriocarcinoma:

32
Ovary, Placenta, Cervix, Liver, Brain, Uterus, Small intestine, Lung

Animal Models for Gestational Choriocarcinoma or affiliated genes

About this section

Publications for Gestational Choriocarcinoma

About this section

Articles related to Gestational Choriocarcinoma:

(show top 50)    (show all 141)
idTitleAuthorsYear
1
Glycan profiling of gestational choriocarcinoma using a lectin microarray. (24424471)
2014
2
Gestational choriocarcinoma at Ibn Rochd Hospital, Casablanca, 2004-2010. (24995750)
2014
3
Gestational choriocarcinoma of the cervix. (25365622)
2014
4
Coexistent gestational choriocarcinoma and mixed adenocarcinoma of the uterus. (24020150)
2013
5
Gestational choriocarcinoma in the fallopian tube. (24219747)
2013
6
Clinical Outcome of a FIGO Stage IV Gestational Choriocarcinoma. (24163669)
2013
7
An unusual cause of lower GI bleeding in a young woman: metastatic gestational choriocarcinoma. (22421497)
2013
8
Subcutaneous mass as the primary manifestation of gestational choriocarcinoma: A case report. (24371601)
2011
9
Gestational choriocarcinoma arising in a tubal ectopic pregnancy: case report. (22053686)
2011
10
Gestational choriocarcinoma in one placenta of dichorionic diamniotic twins who showed severe anemia. (19608272)
2009
11
Acute abdomen as initial presentation of gestational choriocarcinoma. (19288267)
2009
12
Gestational choriocarcinoma: morphological features in a liquid-based endometrial cytological sample. (18181184)
2008
13
Gestational choriocarcinoma arising from a cornual ectopic pregnancy: a case report and review of the literature. (17581760)
2007
14
Pure non-gestational choriocarcinoma of the ovary diagnosed by DNA polymorphism analysis. (16984618)
2006
15
An unusual gestational choriocarcinoma occurring primarily on the surface of a subserous leiomyoma. (14723763)
2004
16
Gestational choriocarcinoma: an unusual presentation with response to gemcitabine and surgery. (15008778)
2004
17
Activity of docetaxel in chemoresistant gestational choriocarcinoma. (11104635)
2000
18
A case of metastatic ovarian non-gestational choriocarcinoma: successful treatment with conservative type surgery and myeloablative chemotherapy. (10986872)
2000
19
Gestational choriocarcinoma whose responsible pregnancy was a complete hydatidiform mole identified by PCR analysis with new sequence tagged site primers. (10645807)
1999
20
Gestational choriocarcinoma. (9443570)
1997
21
Postpartal gestational choriocarcinoma fatally misdiagnosed as squamous cell cancer of the uterine cervix. (9443576)
1997
22
Gestational choriocarcinoma metastatic to the brain treated successfully by stereotactic radiosurgery and chemotherapy. (8871007)
1996
23
An extra gonadal non-gestational choriocarcinoma in a woman treated for an endometrial carcinoma. (7543866)
1995
24
Thoracotomy in the management of gestational choriocarcinoma. A clinicopathologic study. (8374875)
1993
25
Gestational choriocarcinoma in norway, 1953-92 - an epidemiologic report. (21573475)
1993
26
Another case of metastatic gestational choriocarcinoma arising from a primary fallopian tube ectopic pregnancy. (8382441)
1993
27
Documentation of complete resolution of gestational choriocarcinoma in the oophorectomized patient. (8276305)
1993
28
Gestational choriocarcinoma in a tubal ectopic pregnancy. (1315103)
1992
29
Urinary excretion of degradation products of prostacyclin and thromboxane is increased in patients with gestational choriocarcinoma. (1868436)
1991
30
Metastatic gestational choriocarcinoma. Unusual pathologic variant following therapy. (2465817)
1989
31
Establishment and characterization of three new human gestational choriocarcinoma cell lines. (3171272)
1988
32
Gestational choriocarcinoma presenting as endobronchial carcinoma. (3194870)
1988
33
Expression of HLA-DR molecules in human gestational choriocarcinoma cell lines and malignant cell lines. (3658923)
1987
34
Radioimmunoscintigraphic detection of occult gestational choriocarcinoma. (2432784)
1987
35
An immunohistological study of HLA antigen expression by gestational choriocarcinoma. (2408648)
1985
36
Neoplastic cerebral aneurysm from metastatic gestational choriocarcinoma. Case report. (4040960)
1985
37
Clinical analysis of intracranial metastases in gestational choriocarcinoma: a series of 15 cases. (3862401)
1985
38
Resistant gestational choriocarcinoma: successful treatment with vinblastine, bleomycin, and cisplatin (VBP). (6189602)
1983
39
The role of VP16-213 (etoposide; NSC-141540) in gestational choriocarcinoma. (7083462)
1982
40
Gestational choriocarcinoma. Its origin in the placenta during seemingly normal pregnancy. (7235120)
1981
41
The role of thoracotomy in the management of the pulmonary metastases of gestational choriocarcinoma. (1212836)
1975
42
Gestational choriocarcinoma of the tube and ovary. (4730067)
1973
43
Invasive mole and gestational choriocarcinoma in Denmark, 1940-1969. Biological and clinical aspects. (4355252)
1973
44
Chemotherapy of gestational choriocarcinoma. (4641760)
1972
45
Gestational choriocarcinoma. (5065688)
1972
46
Invasive mole, gestational choriocarcinoma and transplantation antigens. (4364364)
1972
47
Chemotherapy of gestational choriocarcinoma: a preliminary report of eight patients treated with methotrexate. (5168900)
1971
48
Extrauterine gestational choriocarcinoma. Report of two cases. (5441265)
1970
49
Histocompatibility antigens on the HL-A locus in gestational choriocarcinoma. (5406845)
1969
50
Gestational choriocarcinoma in the General Hospital of Mexico. Analysis of forty cases. (5659418)
1968

Variations for Gestational Choriocarcinoma

About this section

Expression for genes affiliated with Gestational Choriocarcinoma

About this section
Expression patterns in normal tissues for genes affiliated with Gestational Choriocarcinoma

Search GEO for disease gene expression data for Gestational Choriocarcinoma.

Pathways for genes affiliated with Gestational Choriocarcinoma

About this section

Pathways related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.4CGB5, ENPEP

Compounds for genes affiliated with Gestational Choriocarcinoma

About this section

Compounds related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
1indoleamine4410.1IFNG, CGB5
2oestriol4410.1CGB5, CGB7
3ctp4410.1CGB7, CGB5
4l-nmma4410.1CGB5, IFNG
57,8-dihydroneopterin44 2411.0ALPP, IFNG
6zoledronic acid4410.0IFNG, ALPP
7aphidicolin4410.0ALPP, IFNG
8bleomycin44 1110.9CGB5, CGB7
9pge1449.8ALPP, CGB5
10progestin449.8CGB5, ALPP
11hydroxyurea44 50 1111.8CGB5, ALPP
12prednisolone44 28 1111.8ALPP, IFNG
13sodium dodecylsulfate449.7CGB5, ALPP
14hydrocortisone44 2 61 1112.7IFNG, ALPP
15succinate449.6ALPP, ENPEP
16thyroxine44 2410.6CGB7, ALPP
17nifedipine44 28 50 1112.5CGB5, ALPP
18genistein44 28 61 2 24 1114.5CGB5, ALPP, IFNG
19cyclosporin a44 28 6111.5IFNG, ALPP, CGB5
20pge2449.5CGB5, ALPP, IFNG
21lactate449.5ALPP, CGB7, CGB5
22cycloheximide449.5CGB5, ALPP, IFNG
23cisplatin44 50 61 1112.5CGB5, CGB7, ALPP
24ibmx44 61 2811.4CGB5, ALPP
25testosterone44 61 24 1112.4ALPP, CGB7, CGB5
26dexamethasone44 50 28 1112.3CGB5, ALPP, IFNG
27simvastatin44 50 61 28 24 1114.3ALPP, IFNG
28retinoic acid44 2410.2IFNG, ALPP, CGB7, CGB5
29vegf449.0CGB5, ENPEP, ALPP, IFNG
30arginine448.9CGB5, ENPEP, ALPP, IFNG

GO Terms for genes affiliated with Gestational Choriocarcinoma

About this section

Products for genes affiliated with Gestational Choriocarcinoma

About this section
  • Antibodies
  • Proteins
  • Lysates

Sources for Gestational Choriocarcinoma

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet