MCID: GST052
MIFTS: 38

Gestational Choriocarcinoma malady

Reproductive diseases, Cancer diseases categories

Summaries for Gestational Choriocarcinoma

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63Wikipedia, 32MalaCards
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Wikipedia:63 Gestational choriocarcinoma is a malignant trophoblastic tumour arising from any gestational event... more...

MalaCards: Gestational Choriocarcinoma, also known as molar pregnancy with choriocarcinoma, is related to choriocarcinoma and hypertension. An important gene associated with Gestational Choriocarcinoma is IFNG (interferon, gamma). The compounds oestriol and ctp have been mentioned in the context of this disorder. Affiliated tissues include ovary, placenta and liver.

Aliases & Classifications for Gestational Choriocarcinoma

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Sources:
8Disease Ontology, 10DISEASES, 48Orphanet, 60UMLS, 56SNOMED-CT, 39NCIt, 57SNOMED-CT via Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Reproductive diseases


Characteristics (Orphanet epidemiological data):

48
gestational choriocarcinoma:
Inheritance: Sporadic; Age of onset: Adulthood


Aliases & Descriptions:

gestational choriocarcinoma 8 10 48 60
molar pregnancy with choriocarcinoma 8
gestational chorionepithelioma 8


External Ids:

Disease Ontology8 DOID:2025
NCIt39 C4646
SNOMED-CT via Orphanet57 417570003, 417057000
ICD10 via Orphanet26 C58

Related Diseases for Gestational Choriocarcinoma

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Gestational Choriocarcinoma:



Diseases related to gestational choriocarcinoma

Clinical Features for Gestational Choriocarcinoma

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Drugs & Therapeutics for Gestational Choriocarcinoma

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Gestational Choriocarcinoma

Drug clinical trials:

Search ClinicalTrials for Gestational Choriocarcinoma

Search NIH Clinical Center for Gestational Choriocarcinoma

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Genetic Tests for Gestational Choriocarcinoma

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Anatomical Context for Gestational Choriocarcinoma

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32MalaCards
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MalaCards organs/tissues related to Gestational Choriocarcinoma:

32
Ovary, Placenta, Liver, Cervix, Brain, Uterus, Lung, Small intestine

Animal Models for Gestational Choriocarcinoma or affiliated genes

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Publications for Gestational Choriocarcinoma

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50PubMed
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Articles related to Gestational Choriocarcinoma:

(show top 50)    (show all 152)
idTitleAuthorsYear
1
Glycan profiling of gestational choriocarcinoma using a lectin microarray. (24424471)
2014
2
Coexistent gestational choriocarcinoma and mixed adenocarcinoma of the uterus. (24020150)
2013
3
Gestational choriocarcinoma in the fallopian tube. (24219747)
2013
4
Clinical Outcome of a FIGO Stage IV Gestational Choriocarcinoma. (24163669)
2013
5
Hypersensitivity to Etoposide in case of metastatic gestational choriocarcinoma. (24163666)
2013
6
Treatment of gestational choriocarcinoma and massive ascites by hypothermic intraperitoneal perfusion chemotherapy guided by ultrasound followed by cytoreductive surgery. (24353600)
2013
7
Subcutaneous mass as the primary manifestation of gestational choriocarcinoma: A case report. (24371601)
2011
8
Gestational choriocarcinoma of Fallopian tube diagnosed with a combination of p57KIP2 immunostaining and short tandem repeat analysis: case report. (21599798)
2011
9
Gestational choriocarcinoma analyzed by polymerase chain reaction amplification of polymorphic VNTR and human leukocyte antigen regions. (20435306)
2010
10
Pure primary non-gestational ovarian choriocarcinoma: a diagnostic dilemma. (20090265)
2010
11
A case of non-gestational choriocarcinoma arising in the ovary of a postmenopausal woman. (19809555)
2009
12
Diagnostic dilemma: non-gestational or gestational choriocarcinoma of the ovary. (19322987)
2008
13
Successful treatment of FIGO stage IV gestational choriocarcinoma occurring 2 months after delivery. (17521800)
2008
14
Gestational choriocarcinoma mimicking a uterine adenocarcinoma. (18838707)
2008
15
Intracerebral hemorrhage as initial presentation of gestational choriocarcinoma: a case report and literature review. (17425677)
2007
16
Detection of non-maternal components of gestational choriocarcinoma by PCR-based microsatellite DNA assay. (16740299)
2006
17
Primary omental gestational choriocarcinoma ascertained by deoxyribonucleic acid polymorphism analysis. (15790467)
2005
18
Establishment and characterization of a human gestational choriocarcinoma cell line (HOCC). (15369135)
2004
19
Resistance to multiple agent chemotherapy including cisplatin after chronic low-dose oral etoposide administration in gestational choriocarcinoma. (11586044)
2001
20
Gastric choriocarcinoma shows characteristics of adenocarcinoma and gestational choriocarcinoma: a comparative genomic hybridization and fluorescence in situ hybridization study. (11552718)
2001
21
A case of metastatic ovarian non-gestational choriocarcinoma: successful treatment with conservative type surgery and myeloablative chemotherapy. (10986872)
2000
22
The 15-deoxy-delta(12,14)-prostaglandin J(2)receptor, peroxisome proliferator activated receptor-gamma (PPARgamma) is expressed in human gestational tissues and is functionally active in JEG3 choriocarcinoma cells. (10833383)
2000
23
Expression of aminopeptidase A in human gestational choriocarcinoma cell lines and tissues. (10692253)
2000
24
Unexpected death due to gestational choriocarcinoma: a report of two cases. (9885937)
1998
25
Gestational choriocarcinoma. (9443570)
1997
26
Gestational choriocarcinoma presenting as an extradural mass--a case report. (9491659)
1997
27
Gestational choriocarcinoma of the ovary diagnosed by analysis of tumour DNA. (8640741)
1996
28
Gestational choriocarcinoma of the fallopian tube--a case report. (8772822)
1995
29
Documentation of complete resolution of gestational choriocarcinoma in the oophorectomized patient. (8276305)
1993
30
Oral contraceptive use and gestational choriocarcinoma. (2044074)
1991
31
Metastatic gestational choriocarcinoma. Unusual pathologic variant following therapy. (2465817)
1989
32
Establishment and characterization of three new human gestational choriocarcinoma cell lines. (3171272)
1988
33
Bleomycin, cisplatin and etoposide combination therapy (BCE) in drug-resistant gestational choriocarcinoma. (2467642)
1988
34
Expression of HLA-DR molecules in human gestational choriocarcinoma cell lines and malignant cell lines. (3658923)
1987
35
Neoplastic cerebral aneurysm from metastatic gestational choriocarcinoma. Case report. (4040960)
1985
36
Localization of stage-specific embryonic antigens in hydatidiform mole, normal placenta, and gestational choriocarcinoma. (2856911)
1985
37
The nature of gestational choriocarcinoma latent over two years. (3998550)
1985
38
A method for directly establishing short-term cultures of human gestational choriocarcinoma in vitro. (6478446)
1984
39
Resistant gestational choriocarcinoma: successful treatment with vinblastine, bleomycin, and cisplatin (VBP). (6189602)
1983
40
The role of VP16-213 (etoposide; NSC-141540) in gestational choriocarcinoma. (7083462)
1982
41
Fatal gestational choriocarcinoma. Clinicopathologic study of patients treated at a trophoblastic disease center. (7116308)
1982
42
Pathology of gestational choriocarcinoma induced in patas monkeys by ethylnitrosourea given during pregnancy. (6963958)
1981
43
HL-A antigen frequency distribution in patients with gestational choriocarcinoma and their husbands. (6963960)
1981
44
Gestational choriocarcinoma of the ovary. (7461489)
1980
45
Gestational trophoblastic disease: origin of choriocarcinoma, invasive mole and choriocarcinoma associated with hydatidiform mole, and some immunologic aspects. (210639)
1978
46
Gestational choriocarcinoma of the tube and ovary. (4730067)
1973
47
Recent observations related to the chemotherapy and immunology of gestational choriocarcinoma. (4592978)
1973
48
Chemotherapy of gestational choriocarcinoma. (4641760)
1972
49
Extrauterine gestational choriocarcinoma. Report of two cases. (5441265)
1970
50
Gestational choriocarcinoma in the General Hospital of Mexico. Analysis of forty cases. (5659418)
1968

Genetic Variations for Gestational Choriocarcinoma

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Expression for genes affiliated with Gestational Choriocarcinoma

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gestational Choriocarcinoma

Search GEO for disease gene expression data for Gestational Choriocarcinoma.

Pathways for genes affiliated with Gestational Choriocarcinoma

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Compounds for genes affiliated with Gestational Choriocarcinoma

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44Novoseek, 24HMDB
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Compounds related to Gestational Choriocarcinoma according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1oestriol4410.0CGB7, CGB5
2ctp449.9CGB5, CGB7
3indoleamine449.9CGB5, IFNG
47,8-dihydroneopterin44 2410.5ALPP, IFNG
5zoledronic acid449.4ALPP, IFNG
6aphidicolin449.3IFNG, ALPP
7arginine448.6ALPP, ENPEP, CGB5, IFNG
8vegf448.3ALPP, ENPEP, CGB5, IFNG

GO Terms for genes affiliated with Gestational Choriocarcinoma

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Products for genes affiliated with Gestational Choriocarcinoma

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gestational Choriocarcinoma

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet