MCID: GST059
MIFTS: 23

Gestational Trophoblastic Tumor malady

Cancer diseases category

Summaries for Gestational Trophoblastic Tumor

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63Wikipedia, 32MalaCards
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Wikipedia:63 Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumours. These... more...

MalaCards: Gestational Trophoblastic Tumor, also known as gestational trophoblastic disease, is related to gestational trophoblastic neoplasm and choriocarcinoma. An important gene associated with Gestational Trophoblastic Tumor is ERBB3 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3). The compounds 13,14-dihydro-15-ketoprostaglandin f2alpha and fundal have been mentioned in the context of this disorder. Affiliated tissues include placenta.

Aliases & Classifications for Gestational Trophoblastic Tumor

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42NIH Rare Diseases, 44Novoseek, 60UMLS
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Classifications:

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Global: Cancer diseases


Aliases & Descriptions:

gestational trophoblastic tumor 42 44
gestational trophoblastic disease 42 44
gestational trophoblastic neoplasms 60
gestational trophoblastic neoplasm 42


Related Diseases for Gestational Trophoblastic Tumor

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17GeneCards, 18GeneDecks
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Diseases related to Gestational Trophoblastic Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 57)
idRelated DiseaseScoreTop Affiliating Genes
1gestational trophoblastic neoplasm31.2CGB, CGB5
2choriocarcinoma30.6CGB5, CGB, OXT, STARD7, ERBB3
3placental site trophoblastic tumor30.3CGB, CGB5
4trophoblastic neoplasm10.8
5placenta disease10.7
6gestational choriocarcinoma10.4
7placenta accreta10.2
8pleurisy10.2
9hydatidiform mole, recurrent10.2
10pulmonary tuberculosis10.2
11arteriovenous malformation10.2
12fallopian tube cancer10.2
13hepatitis10.2
14hermaphroditism10.2
15respiratory failure10.2
16tuberculosis10.2
17vaginitis10.2
18epithelioid trophoblastic tumor10.2
19placental insufficiency10.2
20large cell carcinoma10.2
21central nervous system disease10.2
22hyperthyroidism10.2
23lung large cell carcinoma10.2
24nervous system disease10.2
25ovarian disease10.2
26peritonitis10.2
27uterine disease10.2
28vascular disease10.2
29partial hydatidiform mole10.2
30extragonadal germ cell tumor10.0CGB5
31cholangiocarcinoma10.0CGB
32serotonin syndrome10.0CGB
33dysgerminoma10.0CGB5
34gynecomastia10.0CGB5
35leydig cell tumor10.0CGB5
36prolactinoma10.0CGB
37infertility10.0CGB
38endodermal sinus tumor10.0CGB5, CGB
39ectopic pregnancy10.0CGB5, CGB
40seminoma10.0CGB, CGB5
41chorioamnionitis10.0OXT
42cryptococcosis10.0CGB5, CGB
43pregnancy loss10.0CGB5, CGB
44germinoma10.0CGB, CGB5
45diabetes insipidus10.0OXT
46hyperprolactinemia10.0CGB5, CGB
47embryonal cancer10.0CGB, CGB5
48neural tube defects10.0CGB5, CGB
49transitional cell carcinoma10.0CGB5, ERBB3, CGB
50adenocarcinoma10.0CGB5, ERBB3, CGB

Graphical network of the top 20 diseases related to Gestational Trophoblastic Tumor:



Diseases related to gestational trophoblastic tumor

Clinical Features for Gestational Trophoblastic Tumor

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Drugs & Therapeutics for Gestational Trophoblastic Tumor

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Gestational Trophoblastic Tumor

Search CenterWatch for Gestational Trophoblastic Tumor

Genetic Tests for Gestational Trophoblastic Tumor

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Anatomical Context for Gestational Trophoblastic Tumor

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32MalaCards
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MalaCards organs/tissues related to Gestational Trophoblastic Tumor:

32
Placenta

Animal Models for Gestational Trophoblastic Tumor or affiliated genes

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Publications for Gestational Trophoblastic Tumor

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Genetic Variations for Gestational Trophoblastic Tumor

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Expression for genes affiliated with Gestational Trophoblastic Tumor

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gestational Trophoblastic Tumor

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Pathways for genes affiliated with Gestational Trophoblastic Tumor

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Compounds for genes affiliated with Gestational Trophoblastic Tumor

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Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 49PharmGKB, 24HMDB, 59Tocris Bioscience
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Compounds related to Gestational Trophoblastic Tumor according to GeneCards/GeneDecks:

(show all 30)
idCompoundScoreTop Affiliating Genes
113,14-dihydro-15-ketoprostaglandin f2alpha449.5CGB5, OXT
2fundal449.5OXT, CGB5
3oestriol449.5CGB, CGB5
4estradiol benzoate449.5CGB5, OXT
5buserelin44 28 1111.5CGB5, OXT
6ctp449.5CGB5, CGB
7clomiphene citrate449.4CGB5, CGB
8(+-)-pgf2-alpha449.4CGB5, OXT
9ifosfamide44 1110.4CGB5, CGB
10leucovorin44 49 1111.4CGB5, CGB
11naloxone44 49 28 1112.4OXT, CGB5
12prostaglandin f2alpha449.3CGB5, OXT
13phenylephrine44 28 11 2412.3CGB5, OXT
14pge1449.2CGB5, OXT
15bleomycin44 1110.2CGB5, CGB
16androstenedione44 2410.1CGB, CGB5
17progestin449.0CGB5, OXT
18paraffin449.0ERBB3, OXT, CGB5
19forskolin44 49 1111.0OXT, ERBB3, CGB5
20mifepristone44 59 28 1112.0CGB5, CGB, OXT
21methotrexate44 49 1110.9CGB5, CGB, OXT
22gnrh448.9CGB5, CGB, OXT
23corticosterone44 59 2410.8OXT, CGB5
24lactate448.8CGB5, CGB, OXT
25creatinine448.8OXT, CGB, CGB5
26steroid448.7ERBB3, CGB5, OXT
27estradiol44 11 2410.6CGB5, CGB, OXT, ERBB3
28progesterone44 59 28 11 2412.6ERBB3, CGB5, CGB, OXT
29testosterone44 59 11 2411.6CGB5, CGB, OXT, ERBB3
30vegf448.1ERBB3, OXT, ANG, CGB, CGB5

GO Terms for genes affiliated with Gestational Trophoblastic Tumor

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Products for genes affiliated with Gestational Trophoblastic Tumor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gestational Trophoblastic Tumor

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet