MCID: GST059
MIFTS: 34

Gestational Trophoblastic Tumor malady

Rare diseases, Cancer diseases categories

Summaries for Gestational Trophoblastic Tumor

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66Wikipedia, 34MalaCards
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Wikipedia:66 Gestational trophoblastic disease (GTD) is a term used for a group of pregnancy-related tumours. These... more...

MalaCards: Gestational Trophoblastic Tumor, also known as gestational trophoblastic disease, is related to gestational trophoblastic neoplasm and choriocarcinoma. An important gene associated with Gestational Trophoblastic Tumor is ERBB3 (v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3). The compounds 13,14-dihydro-15-ketoprostaglandin f2alpha and fundal have been mentioned in the context of this disorder. Affiliated tissues include placenta, brain and liver.

Aliases & Classifications for Gestational Trophoblastic Tumor

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44NIH Rare Diseases, 46Novoseek, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


Aliases & Descriptions:

gestational trophoblastic tumor 44 46
gestational trophoblastic disease 44 46
gestational trophoblastic neoplasms 63
gestational trophoblastic neoplasm 44


Related Diseases for Gestational Trophoblastic Tumor

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Gestational Trophoblastic Tumor:



Diseases related to gestational trophoblastic tumor

Symptoms for Gestational Trophoblastic Tumor

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Drugs & Therapeutics for Gestational Trophoblastic Tumor

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Gestational Trophoblastic Tumor

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Anatomical Context for Gestational Trophoblastic Tumor

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34MalaCards
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MalaCards organs/tissues related to Gestational Trophoblastic Tumor:

34
Placenta, Brain, Liver

Animal Models for Gestational Trophoblastic Tumor or affiliated genes

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Publications for Gestational Trophoblastic Tumor

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53PubMed
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Articles related to Gestational Trophoblastic Tumor:

(show top 50)    (show all 57)
idTitleAuthorsYear
1
Current issues in the histopathology of gestational trophoblastic tumors. (20055562)
2010
2
Gestational trophoblastic tumor with liver metastasis after misoprostol abortion. (18762963)
2009
3
Practical issues in the management of low-risk gestational trophoblast tumors. (19004403)
2008
4
Evaluation of treatment relating to gestational trophoblastic tumor registered to the French Trophoblastic Disease Reference Center (TDRC) in Lyon from 1999 to 2005]. (17336125)
2007
5
Efficacy of the FAEV regimen in the treatment of high-risk, drug-resistant gestational trophoblastic tumor. (17977170)
2007
6
Gestational trophoblastic tumor at a tertiary level cancer center: a retrospective study. (17165433)
2006
7
Recurrent gestational trophoblastic tumor: management and risk factors for recurrence. (16750258)
2006
8
Gestational trophoblastic tumor in pregnancy: a case report and review of the literature. (16681776)
2006
9
Relapse rate of patients with low-risk gestational trophoblastic tumor initially treated with single-agent chemotherapy. (15721402)
2005
10
Diagnostic and prognostic significance of circulating tumor suppressor gene p53 autoantibodies in patients with gestational trophoblastic tumors. (15068319)
2004
11
Floxuridine-containing regimens in the treatment of gestational trophoblastic tumor. (15283053)
2004
12
Early pregnancy outcomes after chemotherapy for gestational trophoblastic tumor. (15305824)
2004
13
Salvage chemotherapy for high-risk gestational trophoblastic tumor. (15283050)
2004
14
EMA/EP chemotherapy for chemorefractory gestational trophoblastic tumor. (15283051)
2004
15
Risk of abnormal pregnancy completing chemotherapy for gestational trophoblastic tumor. (12586587)
2003
16
Successful term pregnancy after selective arterial embolization of symptomatic arteriovenous malformation in the setting of gestational trophoblastic tumor. (12504631)
2003
17
Correlation of risk categorization in gestational trophoblastic tumor between old and new combined staging and scoring system. (12696623)
2003
18
Significance of serum/cerebrospinal fluid human chorionic gonadotropin ratio and prophylactic intrathecal therapy in patients with brain metastases of gestational trophoblast tumor]. (14728849)
2003
19
Gestational trophoblastic tumor after medical abortion. (12738129)
2003
20
18F]fluorodeoxyglucose positron emission tomography as a useful indicator of metastatic gestational trophoblastic tumor: preliminary results in three patients. (14529686)
2003
21
Angiogenin and gestational trophoblastic tumors, a promising prognostic marker. (12705339)
2003
22
Doppler ultrasonography of the uterine artery and the response to chemotherapy in patients with gestational trophoblastic tumors. (12006530)
2002
23
Coexisting true hermaphroditism and partial hydatidiform mole developing metastatic gestational trophoblastic tumors. A case report. (12447683)
2002
24
Subsequent pregnancy experience in patients with molar pregnancy and gestational trophoblastic tumor. (12063876)
2002
25
Clinical characteristics and treatment of gestational trophoblastic tumor with vaginal metastasis. (11855880)
2002
26
Pregnancy outcomes of patients who conceived within 1 year after chemotherapy for gestational trophoblastic tumor: a clinical report of 22 patients. (11585428)
2001
27
Guidelines for the stratification of patients recruited to trials of therapy for low-risk gestational trophoblastic tumor. (10926786)
2000
28
CSF/serum beta-hCG ratio in patients with brain metastases of gestational trophoblastic tumor. (10710737)
2000
29
The role of hysterectomy in the therapy of gestational trophoblastic tumor. (12899400)
2000
30
Clinical study of four cases with malignant gestation trophoblastic tumor after mifepristone abortion]. (11286033)
2000
31
Pregnancy outcome after treatment with etoposide (VP-16) for low-risk gestational trophoblastic tumor. (11240760)
1999
32
Clinical assessment of EMA/CO induced DNA damage in peripheral blood lymphocytes of high-risk gestational trophoblastic tumor patients. (10376437)
1999
33
Diagnosis and treatment of the malignant gestational trophoblastic tumor with pulmonary metastasis complicated with pulmonary tuberculosis. (12894897)
1999
34
Outcome of pregnancies occurring before completion of human chorionic gonadotropin follow-up in patients with persistent gestational trophoblastic tumor. (10366457)
1999
35
Pregnancy outcome of patients conceiving within one year after chemotherapy for gestational trophoblastic tumor: a clinical report of 22 cases. (11189204)
1998
36
The role of transvaginal ultrasonography in the management of gestational trophoblastic tumor. (7741920)
1995
37
Brain metastases of gestational trophoblastic tumor. (7518516)
1994
38
Pulmonary metastases of gestational trophoblastic tumor. Risk factors for early respiratory failure. (8035373)
1994
39
Evaluation of prognostic factors and staging in gestational trophoblastic tumor. (7970479)
1994
40
Liver metastases of gestational trophoblastic tumor. (8380786)
1993
41
Staging rules for gestational trophoblastic tumors and fallopian tube cancer. (1317647)
1992
42
Correlation of plasma methotrexate concentration with human chorionic gonadotropin and therapeutic response to low-dose methotrexate-citrovorum factor in low-medium-risk gestational trophoblastic tumors. (1646754)
1991
43
The role of contraception in the development of postmolar gestational trophoblastic tumor. (1648697)
1991
44
Duplex ultrasonography for persistent gestational trophoblastic tumor. (2008004)
1991
45
Experience of human chorionic gonadotropin assays in gestational trophoblastic tumors. (1680961)
1991
46
Flow cytometric analysis of DNA content in partial hydatidiform moles with persistent gestational trophoblastic tumor. (1845777)
1991
47
Persistent gestational trophoblastic tumor after partial hydatidiform mole. (2156765)
1990
48
Evaluation of management of gestational trophoblastic tumor in National Taiwan University Hospital. (2543310)
1989
49
Multidisciplinary approach in the management of gestational trophoblastic tumor (GTT). (2543312)
1989
50
Immunobiology of complete molar pregnancy and gestational trophoblastic tumor. (3030577)
1986

Variations for Gestational Trophoblastic Tumor

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Expression for genes affiliated with Gestational Trophoblastic Tumor

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2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gestational Trophoblastic Tumor

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Pathways for genes affiliated with Gestational Trophoblastic Tumor

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Compounds for genes affiliated with Gestational Trophoblastic Tumor

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46Novoseek, 30IUPHAR, 12DrugBank, 52PharmGKB, 25HMDB, 62Tocris Bioscience
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Compounds related to Gestational Trophoblastic Tumor according to GeneCards/GeneDecks:

(show all 32)
idCompoundScoreTop Affiliating Genes
113,14-dihydro-15-ketoprostaglandin f2alpha469.5CGB5, OXT
2fundal469.5CGB5, OXT
3estradiol benzoate469.5OXT, CGB5
4buserelin46 30 1211.5CGB5, OXT
5(+-)-pgf2-alpha469.5CGB5, OXT
6naloxone46 30 52 1212.5CGB5, OXT
7prostaglandin f2alpha469.5CGB5, OXT
8phenylephrine46 30 25 1212.5CGB5, OXT
9pge1469.4CGB5, OXT
10progestin469.4CGB5, OXT
11corticosterone46 62 2511.4OXT, CGB5
12mifepristone46 30 62 1212.4CGB5, OXT
13nifedipine46 30 52 1212.4CGB5, OXT
14nicotine46 30 52 1212.4OXT, CGB5
15prostaglandin469.3CGB5, OXT
16acth469.3CGB5, OXT
17aspirin46 52 30 2512.3OXT, CGB5
18gnrh469.2CGB5, OXT
19methotrexate52 46 1211.2OXT, CGB5
20ethanol46 52 25 1212.2CGB5, ERBB3
21epinephrine46 25 1211.1CGB5, OXT
22estradiol46 25 1211.0CGB5, ERBB3, OXT
23paraffin469.0OXT, ERBB3, CGB5
24forskolin46 52 1211.0CGB5, ERBB3, OXT
25ascorbic acid46 2510.0CGB5, OXT
26progesterone46 30 62 25 1213.0OXT, ERBB3, CGB5
27testosterone46 62 25 1212.0CGB5, ERBB3, OXT
28steroid469.0OXT, ERBB3, CGB5
29estrogen468.9CGB5, ERBB3, OXT
30tamoxifen46 52 30 1211.9CGB5, ERBB3
31nitric oxide46 25 1210.9OXT, ANG, CGB5
32vegf468.5CGB5, ERBB3, ANG, OXT

GO Terms for genes affiliated with Gestational Trophoblastic Tumor

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17Gene Ontology
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Cellular components related to Gestational Trophoblastic Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular spaceGO:0056159.0ERBB3, ANG, OXT

Biological processes related to Gestational Trophoblastic Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1heart developmentGO:0075079.5ERBB3, OXT

Products for genes affiliated with Gestational Trophoblastic Tumor

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gestational Trophoblastic Tumor

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet