MCID: GNT020
MIFTS: 34

Giant Congenital Nevus malady

Rare diseases, Skin diseases, Cancer diseases categories

Summaries for Giant Congenital Nevus

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Genetics Home Reference:21 Giant congenital melanocytic nevus is a skin condition characterized by an abnormally dark, noncancerous skin patch (nevus) that is composed of pigment-producing cells called melanocytes. It is present from birth (congenital) or is noticeable soon after birth. The nevus may be small in infants, but it will usually grow at the same rate the body grows and will eventually be at least 40 cm (15.75 inches) across. The nevus can appear anywhere on the body, but it is more often found on the trunk or limbs. The color ranges from tan to black and can become darker or lighter over time. The surface of a nevus can be flat, rough, raised, thickened, or bumpy; the surface can vary in different regions of the nevus, and it can change over time. The skin of the nevus is often dry and prone to irritation and itching (dermatitis). Excessive hair growth (hypertrichosis) can occur within the nevus. There is often less fat tissue under the skin of the nevus; the skin may appear thinner there than over other areas of the body.

MalaCards based summary: Giant Congenital Nevus, also known as giant pigmented hairy nevus, is related to melanoma and hyperekplexia, and has symptoms including hypertrichosis, hydrocephalus and pruritus. An important gene associated with Giant Congenital Nevus is NRAS (neuroblastoma RAS viral (v-ras) oncogene homolog), and among its related pathways are Signaling by GPCR and Basal cell carcinoma. Affiliated tissues include skin and thyroid, and related mouse phenotypes are limbs/digits/tail and integument.

NIH Rare Diseases:41 A giant congenital nevus is a dark-colored, often hairy patch of skin that is present at birth. it is usually smaller in infants and children, but continues to grow with the child. a giant pigmented nevus is usually larger than 20cm in diameter once it stops growing. they are often found on the buttocks, which is known as "bathing trunk" nevi. individuals with giant congenital nevi have an increased chance of developing some type of skin cancer, including malignant melanoma. last updated: 3/17/2015

Wikipedia:63 The congenital melanocytic nevus is a type of melanocytic nevus (or mole) found in infants at birth.... more...

Aliases & Classifications for Giant Congenital Nevus

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Sources:
41NIH Rare Diseases, 21Genetics Home Reference, 47Orphanet, 60UMLS, 26ICD10 via Orphanet, 61UMLS via Orphanet
See all sources

Giant Congenital Nevus, Aliases & Descriptions:

Name: Giant Congenital Nevus 41
Giant Pigmented Hairy Nevus 41 21 47 60
Giant Congenital Melanocytic Nevus 41 21 47
Gmn 41 21 47
Large Congenital Melanocytic Nevus 41 47
Congenital Pigmented Nevus 41 47
Giant Pigmented Nevus 41 60
Gphn 41 21
Lcmn 41 47
 
Congenital Giant Pigmented Nevus of Skin 21
Congenital Melanocytic Nevus Syndrome 21
Giant Congenital Melanocytic Nevi 21
Giant Congenital Pigmented Nevus 21
Congenital Giant Pigmented Nevus 41
Congenital Melanocytic Nevus 60
Congenital Hairy Nevus 41
Bathing Trunk Nevus 41
Giant Hairy Nevus 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases
Anatomical: Skin diseases


Characteristics (Orphanet epidemiological data):

47
giant pigmented hairy nevus:
Prevalence: 1-9/100000 (Europe); Age of onset: Infancy,Neonatal; Age of death: normal life expectancy


External Ids:

Orphanet47 626
ICD10 via Orphanet26 D22
UMLS via Orphanet61 C1318558, C1842036

Related Diseases for Giant Congenital Nevus

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Diseases related to Giant Congenital Nevus via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 50)
idRelated DiseaseScoreTop Affiliating Genes
1melanoma30.3MC1R, NRAS
2hyperekplexia10.5
3molybdenum cofactor deficiency c10.5
4molybdenum cofactor deficiency10.5
5hypophosphatemic rickets10.4
6rickets10.4
7epidermal nevus, somatic10.4
8encephalopathy due to sulfite oxidase deficiency10.4
9congenital fiber-type disproportion10.3
10choroid plexus papilloma10.3
11choroiditis10.3
12papilloma10.3
13aplasia cutis congenita10.3
14cutis verticis gyrata10.3
15spina bifida occulta10.3
16scalp syndrome10.3
17lipoma10.3
18lipomatosis10.3
19gphn-related hyperekplexia10.3
20arachnoiditis10.3
21arachnoid cysts10.3
22hypercalcemia10.3
23arteriovenous malformation10.3
24angiolipoma10.3
25intracranial arteriovenous malformation10.3
26melanocytic nevus syndrome, congenital, somatic10.3
27neurocutaneous melanosis, somatic10.3
28choristoma10.3
29hyperekplexia, hereditary 1, autosomal dominant or recessive10.2
30geniculate herpes zoster10.2
31herpes zoster10.2
32stiff-person syndrome10.2
33rhabdomyosarcoma10.1
34congenital smooth muscle hamartoma10.1
35plexiform neurofibroma10.1
36cutaneous ganglioneuroma10.1
37ganglioneuroma10.1
38malignant peripheral nerve sheath tumor10.1
39neurofibroma10.1
40thyroid cancer10.1
41thyroiditis10.1
42mills syndrome10.1
43schizophrenia10.0
44rheumatoid arthritis10.0
45molybdenum cofactor deficiency a10.0
46leukemia10.0
47neuronitis10.0
48retinopathy pigmentary mental retardation10.0
49breast cancer9.9MC1R, NRAS
50uveal melanoma9.8MC1R, NRAS

Graphical network of the top 20 diseases related to Giant Congenital Nevus:



Diseases related to giant congenital nevus

Symptoms for Giant Congenital Nevus

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Symptoms:

 47 (show all 14)
  • abnormal pigmentary skin changes/skin pigmentation anomalies
  • capillary hemangioma/nevus/naevus flammeus/port-wine stain
  • scalp cyst/giant nevus
  • hirsutism/hypertrichosis/increased body hair
  • neoplasms/tumors
  • pruritus/itching
  • irregular/patchy skin hypopigmentation
  • subcutaneous nodules/lipomas/tumefaction/swelling
  • hydrocephaly
  • seizures/epilepsy/absences/spasms/status epilepticus
  • melanoma
  • skin/cutaneous neoplasm/tumor/carcinoma/cancer (excluding melanoma)
  • sarcoma
  • soft tissue sarcoma/cancer/tumor/liposarcoma/myosarcoma

HPO human phenotypes related to Giant Congenital Nevus:

(show all 8)
id Description Frequency HPO Source Accession
1 hypertrichosis typical (50%) HP:0000998
2 hydrocephalus occasional (7.5%) HP:0000238
3 pruritus occasional (7.5%) HP:0000989
4 hypopigmented skin patches occasional (7.5%) HP:0001053
5 seizures occasional (7.5%) HP:0001250
6 melanoma occasional (7.5%) HP:0002861
7 neoplasm of the skin occasional (7.5%) HP:0008069
8 sarcoma occasional (7.5%) HP:0100242

Drugs & Therapeutics for Giant Congenital Nevus

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Drug clinical trials:

Search ClinicalTrials for Giant Congenital Nevus

Search NIH Clinical Center for Giant Congenital Nevus

Genetic Tests for Giant Congenital Nevus

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Anatomical Context for Giant Congenital Nevus

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MalaCards organs/tissues related to Giant Congenital Nevus:

31
Skin, Thyroid

Animal Models for Giant Congenital Nevus or affiliated genes

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MGI Mouse Phenotypes related to Giant Congenital Nevus:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053719.1NRAS, MC1R
2MP:00107719.1NRAS, MC1R
3MP:00020069.0NRAS, MC1R
4MP:00030128.8NRAS, MC1R

Publications for Giant Congenital Nevus

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Articles related to Giant Congenital Nevus:

(show all 20)
idTitleAuthorsYear
1
Giant congenital nevus associated with papillary thyroid cancer: the first case report. (23968452)
2013
2
Impressive pseudotumoral proliferative nodules in a giant congenital nevus of a newborn. (22958141)
2013
3
A rare association of congenital lumbar hernia and giant congenital nevus. (22648191)
2013
4
Giant congenital nevus with plexiform neurofibroma and malignant peripheral nerve sheath tumor. (22413842)
2012
5
Wells on natural selection: right for the wrong reason--described a giant congenital nevus. (22256630)
2011
6
Images in clinical medicine. Giant congenital nevus. (19726769)
2009
7
Treatment of giant congenital nevus of the back by convergent serial excision. (18837711)
2008
8
Desmoplastic giant congenital nevus with progressive depigmentation. (17097364)
2007
9
A giant congenital nevus spilus in an 8-year-old girl. (17142204)
2006
10
Cutaneous ganglioneuroma within a giant congenital nevus. (24223002)
2005
11
Giant congenital nevus with progressive sclerodermoid reaction in a newborn. (11576407)
2001
12
A newborn with nodular ulcerated lesion on a giant congenital nevus. (10990581)
2000
13
Poliosis associated with a giant congenital nevus. (10411174)
1999
14
Giant congenital nevus. (10829894)
1995
15
Very late metastasis (27 years) of cutaneous malignant melanoma arising in a halo giant congenital nevus. (8075446)
1994
16
Chromosomal findings in cultured melanocytes from a giant congenital nevus. (8330286)
1993
17
Giant congenital nevus and chronic progressive ascending hemiparesis (Mills syndrome). Report of a case. (1624284)
1992
18
Giant congenital nevus and malignant melanoma. (2715664)
1989
19
Giant congenital nevus and melanoma. (3716969)
1986
20
Giant congenital nevus as a basis for the development of malignant melanoma. (4036470)
1985

Variations for Giant Congenital Nevus

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Clinvar genetic disease variations for Giant Congenital Nevus:

6
id Gene Variation Type Significance SNP ID Assembly Location
1NRASNM_002524.4(NRAS): c.37G> C (p.Gly13Arg)single nucleotide variantPathogenicrs121434595GRCh37Chr 1, 115258745: 115258745
2NRASNM_002524.4(NRAS): c.182A> G (p.Gln61Arg)single nucleotide variantPathogenicrs11554290GRCh37Chr 1, 115256529: 115256529
3NM_002524.4(NRAS): c.181C> A (p.Gln61Lys)single nucleotide variantPathogenicrs121913254GRCh37Chr 1, 115256530: 115256530

Cosmic variations for Giant Congenital Nevus:

7 (show all 271)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1564NRASskin,neck,malignant melanoma,NS3
246511NRASskin,trunk,malignant melanoma,NS3
328049NRASskin,trunk,malignant melanoma,NS3
4222543NRASskin,trunk,malignant melanoma,NS3
5569NRASskin,neck,malignant melanoma,NS3
628048NRASskin,trunk,malignant melanoma,NS3
7580NRASskin,neck,malignant melanoma,NS3
81167936BRAFskin,neck,malignant melanoma,NS3
9471BRAFskin,neck,malignant melanoma,NS3
10475BRAFskin,trunk,malignant melanoma,NS3
11478BRAFskin,trunk,malignant melanoma,NS3
121131BRAFskin,trunk,malignant melanoma,NS3
131167890BRAFskin,trunk,malignant melanoma,NS3
14476BRAFskin,buttock,malignant melanoma,NS3
1544216TP53skin,trunk,malignant melanoma,NS3
1644057TP53skin,trunk,malignant melanoma,NS3
1745544TP53skin,neck,malignant melanoma,NS3
181167962TP53skin,neck,malignant melanoma,NS3
1944630TP53skin,neck,malignant melanoma,NS3
2045413TP53skin,trunk,malignant melanoma,NS3
21223023APCskin,trunk,malignant melanoma,NS3
22223024APCskin,trunk,malignant melanoma,NS3
23223025APCskin,trunk,malignant melanoma,NS3
2419010APCskin,neck,malignant melanoma,NS3
251167972NF1skin,trunk,malignant melanoma,NS3
261167999NF1skin,neck,malignant melanoma,NS3
271167889NF1skin,trunk,malignant melanoma,NS3
28223406ANK3skin,trunk,malignant melanoma,NS3
291702518ANK3skin,neck,malignant melanoma,NS3
30109251ANK3skin,neck,malignant melanoma,NS3
311691930ERBB4skin,neck,malignant melanoma,NS3
32226516ERBB4skin,trunk,malignant melanoma,NS3
33229461ERBB4skin,trunk,malignant melanoma,NS3
341700368GEMskin,neck,malignant melanoma,NS3
351700369GEMskin,trunk,malignant melanoma,NS3
36223304MTBPskin,trunk,malignant melanoma,NS3
371700589MTBPskin,neck,malignant melanoma,NS3
38222690MSH6skin,trunk,malignant melanoma,NS3
39226502MSH6skin,trunk,malignant melanoma,NS3
40222528PTCH2skin,trunk,malignant melanoma,NS3
411687606PTCH2skin,neck,malignant melanoma,NS3
42223590GIT2skin,trunk,malignant melanoma,NS3
43223591GIT2skin,trunk,malignant melanoma,NS3
44223681PRKD1skin,trunk,malignant melanoma,NS3
45223679PRKD1skin,trunk,malignant melanoma,NS3
46222602PRG4skin,trunk,malignant melanoma,NS3
47229437PRG4skin,trunk,malignant melanoma,NS3
48223202CTTNBP2skin,trunk,malignant melanoma,NS3
49229071CTTNBP2skin,trunk,malignant melanoma,NS3
505692CTNNB1skin,trunk,malignant melanoma,NS3
515730CTNNB1skin,trunk,malignant melanoma,NS3
52222803SCAPskin,trunk,malignant melanoma,NS3
53228038SCAPskin,trunk,malignant melanoma,NS3
54223214DGKIskin,trunk,malignant melanoma,NS3
551699400DGKIskin,neck,malignant melanoma,NS3
56228929EPHA6skin,trunk,malignant melanoma,NS3
57145371EPHA6skin,trunk,malignant melanoma,NS3
58224033RBL1skin,trunk,malignant melanoma,NS3
591713430RBL1skin,neck,malignant melanoma,NS3
60229499ROS1skin,trunk,malignant melanoma,NS3
61228087ROS1skin,trunk,malignant melanoma,NS3
62223628FLT3skin,trunk,malignant melanoma,NS3
631706595FLT3skin,neck,malignant melanoma,NS3
64223523GRIN2Bskin,trunk,malignant melanoma,NS3
65225001GRIN2Bskin,trunk,malignant melanoma,NS3
66223307ASAP1skin,trunk,malignant melanoma,NS3
67226642ASAP1skin,trunk,malignant melanoma,NS3
68224827KIAA1804skin,trunk,malignant melanoma,NS3
69229440KIAA1804skin,trunk,malignant melanoma,NS3
70532KRASskin,neck,malignant melanoma,NS3
71518KRASskin,neck,malignant melanoma,NS3
72229374TPTEskin,trunk,malignant melanoma,NS3
731686319TPTEskin,trunk,malignant melanoma,NS3
74229296KDM6Bskin,trunk,malignant melanoma,NS3
75229580KDM6Bskin,trunk,malignant melanoma,NS3
76223757TP53BP1skin,trunk,malignant melanoma,NS3
77225033TP53BP1skin,trunk,malignant melanoma,NS3
78223001ERBB2IPskin,trunk,malignant melanoma,NS3
791697994ENPP3skin,neck,malignant melanoma,NS3
80226531EPHB1skin,trunk,malignant melanoma,NS3
81222946INPP4Bskin,trunk,malignant melanoma,NS3
82224996HINFPskin,trunk,malignant melanoma,NS3
83229338HIPK4skin,trunk,malignant melanoma,NS3
84224927EPHA7skin,trunk,malignant melanoma,NS3
85108101HMGCLL1skin,neck,malignant melanoma,NS3
861703588IPO7skin,neck,malignant melanoma,NS3
87230562IRX2skin,trunk,malignant melanoma,NS3
88224101EP300skin,trunk,malignant melanoma,NS3
89228236ISXskin,trunk,malignant melanoma,NS3
901698388ITGB8skin,neck,malignant melanoma,NS3
911692051EPHA4skin,neck,malignant melanoma,NS3
921705902IRAK3skin,neck,malignant melanoma,NS3
93131743EPHA10skin,neck,malignant melanoma,NS3
941708088FRMD5skin,neck,malignant melanoma,NS3
95230728FRMD6skin,trunk,malignant melanoma,NS3
961687338EIF3Iskin,neck,malignant melanoma,NS3
971706604FLT1skin,neck,malignant melanoma,NS3
98224949GIMAP8skin,trunk,malignant melanoma,NS3
99106405GRIN2Askin,neck,malignant melanoma,NS3
100200981GNAT2skin,neck,malignant melanoma,NS3
101223862GIT1skin,trunk,malignant melanoma,NS3
102223906GRB2skin,trunk,malignant melanoma,NS3
1031699990FGFR1skin,neck,malignant melanoma,NS3
104222953FBXW7skin,trunk,malignant melanoma,NS3
105229293FBXO39skin,trunk,malignant melanoma,NS3
1061698794HGFskin,neck,malignant melanoma,NS3
107230804HCKskin,trunk,malignant melanoma,NS3
108223197HBP1skin,trunk,malignant melanoma,NS3
1091704370FCHSD2skin,trunk,malignant melanoma,NS3
110223211EXOC4skin,trunk,malignant melanoma,NS3
1111701610ASTN2skin,neck,malignant melanoma,NS3
112225833ASXL2skin,trunk,malignant melanoma,NS3
113221637ASTN1skin,neck,malignant melanoma,NS3
114223820ASB7skin,trunk,malignant melanoma,NS3
115223803ARNT2skin,trunk,malignant melanoma,NS3
116225027ASB2skin,trunk,malignant melanoma,NS3
1171699238ASZ1skin,neck,malignant melanoma,NS3
1181706222BTBD11skin,trunk,malignant melanoma,NS3
119230716BRCA2skin,trunk,malignant melanoma,NS3
120229460BMPR2skin,trunk,malignant melanoma,NS3
121226451BARHL2skin,trunk,malignant melanoma,NS3
122223686BAZ1Askin,trunk,malignant melanoma,NS3
123136503ARAP3skin,neck,malignant melanoma,NS3
124226814APC2skin,trunk,malignant melanoma,NS3
125229231ACVRL1skin,trunk,malignant melanoma,NS3
126226464ADAM15skin,trunk,malignant melanoma,NS3
127224697ADAM32skin,trunk,malignant melanoma,NS3
128223805ACANskin,trunk,malignant melanoma,NS3
129230750ABCC12skin,trunk,malignant melanoma,NS3
130223871ACACAskin,trunk,malignant melanoma,NS3
1311709432ADAMTS18skin,neck,malignant melanoma,NS3
132222920ADAMTS3skin,trunk,malignant melanoma,NS3
133230647ANKS6skin,trunk,malignant melanoma,NS3
1341702194APBB1IPskin,neck,malignant melanoma,NS3
135222743ANKRD44skin,trunk,malignant melanoma,NS3
136222921ANKRD17skin,trunk,malignant melanoma,NS3
137223250ANK1skin,trunk,malignant melanoma,NS3
138223919DLGAP1skin,trunk,malignant melanoma,NS3
139224905DNAH5skin,trunk,malignant melanoma,NS3
140228077DNAH8skin,trunk,malignant melanoma,NS3
141168844DIRAS2skin,trunk,malignant melanoma,NS3
142224873DHFRL1skin,trunk,malignant melanoma,NS3
143141575DBPskin,neck,malignant melanoma,NS3
144222534JAK1skin,trunk,malignant melanoma,NS3
145223104DSTskin,trunk,malignant melanoma,NS3
146228847E2F6skin,trunk,malignant melanoma,NS3
147223047DSPskin,trunk,malignant melanoma,NS3
1481713699DOK5skin,neck,malignant melanoma,NS3
149225048DRG2skin,trunk,malignant melanoma,NS3
150223299CSMD3skin,trunk,malignant melanoma,NS3
151224768CCNB3skin,trunk,malignant melanoma,NS3
152225089CDH4skin,trunk,malignant melanoma,NS3
153223507CCDC15skin,trunk,malignant melanoma,NS3
154222826CBLBskin,trunk,malignant melanoma,NS3
155225058CASKIN2skin,trunk,malignant melanoma,NS3
1561704663CBLskin,neck,malignant melanoma,NS3
157109450CDH6skin,neck,malignant melanoma,NS3
158229287CDH8skin,trunk,malignant melanoma,NS3
159228832CR2skin,trunk,malignant melanoma,NS3
1601696550CSF1Rskin,neck,malignant melanoma,NS3
161224993CNTN5skin,trunk,malignant melanoma,NS3
162222768CHL1skin,trunk,malignant melanoma,NS3
16313830CDKN2Askin,trunk,malignant melanoma,NS3
164223379EHMT1skin,trunk,malignant melanoma,NS3
1651711182KLHL14skin,neck,malignant melanoma,NS3
166226798SOCS7skin,trunk,malignant melanoma,NS3
167230760SSH2skin,trunk,malignant melanoma,NS3
168224870STAB1skin,trunk,malignant melanoma,NS3
1691713653SNAI1skin,neck,malignant melanoma,NS3
170222495SMAD3skin,trunk,malignant melanoma,NS3
1711706676SMAD9skin,trunk,malignant melanoma,NS3
1721698426STK31skin,neck,malignant melanoma,NS3
173225901SUCLA2skin,trunk,malignant melanoma,NS3
174223670TEP1skin,trunk,malignant melanoma,NS3
1751710558TEX14skin,neck,malignant melanoma,NS3
176230626TCEA1skin,trunk,malignant melanoma,NS3
177225109TAF1skin,trunk,malignant melanoma,NS3
1781690751SUCLG1skin,neck,malignant melanoma,NS3
179229630TAB3skin,trunk,malignant melanoma,NS3
1801690846SLC9A4skin,neck,malignant melanoma,NS3
181222834SLC35A5skin,trunk,malignant melanoma,NS3
182226807RIT2skin,trunk,malignant melanoma,NS3
183223881RND2skin,trunk,malignant melanoma,NS3
184229130RNF20skin,trunk,malignant melanoma,NS3
185222909RELL1skin,trunk,malignant melanoma,NS3
186228191RBL2skin,trunk,malignant melanoma,NS3
187223152RALAskin,trunk,malignant melanoma,NS3
188225014RB1skin,trunk,malignant melanoma,NS3
189228795ROR1skin,trunk,malignant melanoma,NS3
190223190SH2B2skin,trunk,malignant melanoma,NS3
191223043SH3PXD2Bskin,trunk,malignant melanoma,NS3
192106678RUNX2skin,neck,malignant melanoma,NS3
193229267RYR3skin,trunk,malignant melanoma,NS3
1941713709TFAP2Cskin,neck,malignant melanoma,NS3
195226659VAV2skin,trunk,malignant melanoma,NS3
196226749VRTNskin,trunk,malignant melanoma,NS3
19739271UGDHskin,neck,malignant melanoma,NS3
198230547UCHL1skin,trunk,malignant melanoma,NS3
199223293UBR5skin,trunk,malignant melanoma,NS3
200228200YES1skin,trunk,malignant melanoma,NS3
2011688017ZNF644skin,neck,malignant melanoma,NS3
202226513ZNF804Askin,trunk,malignant melanoma,NS3
203224737ZNF609skin,trunk,malignant melanoma,NS3
204223971ZNF433skin,trunk,malignant melanoma,NS3
205228225ZNF222skin,trunk,malignant melanoma,NS3
2061707684TTC8skin,neck,malignant melanoma,NS3
207223300TRPS1skin,trunk,malignant melanoma,NS3
208223232TNKSskin,trunk,malignant melanoma,NS3
2091691990TNS1skin,trunk,malignant melanoma,NS3
210226651TLN1skin,trunk,malignant melanoma,NS3
2111714036TFF2skin,neck,malignant melanoma,NS3
212224065TIAM1skin,trunk,malignant melanoma,NS3
213228053TP63skin,trunk,malignant melanoma,NS3
2141686906TP73skin,neck,malignant melanoma,NS3
215228908TRPM8skin,trunk,malignant melanoma,NS3
2161699411TRIM24skin,neck,malignant melanoma,NS3
217221801TPTE2skin,trunk,malignant melanoma,NS3
218125734RAC1skin,trunk,malignant melanoma,NS3
219230451MSH4skin,trunk,malignant melanoma,NS3
220230656MTPAPskin,trunk,malignant melanoma,NS3
2211695917MSH3skin,trunk,malignant melanoma,NS3
222223859MAPK7skin,trunk,malignant melanoma,NS3
2231685926MORC1skin,neck,malignant melanoma,NS3
224224897MUC7skin,trunk,malignant melanoma,NS3
225226859MXRA5skin,trunk,malignant melanoma,NS3
226162851NDNskin,trunk,malignant melanoma,NS3
227222525NFYCskin,trunk,malignant melanoma,NS3
228226597NPSR1skin,trunk,malignant melanoma,NS3
2291694251N4BP2skin,neck,malignant melanoma,NS3
230223420MYOFskin,trunk,malignant melanoma,NS3
2311707528MAP3K9skin,neck,malignant melanoma,NS3
232223552MAP3K12skin,trunk,malignant melanoma,NS3
233228829KIF21Bskin,trunk,malignant melanoma,NS3
2341698838KIAA1324Lskin,neck,malignant melanoma,NS3
2351691228KCNH7skin,neck,malignant melanoma,NS3
236230695KDM5Askin,trunk,malignant melanoma,NS3
237223878KLHL11skin,trunk,malignant melanoma,NS3
238225924ZNF837skin,trunk,malignant melanoma,NS3
239229506LMTK2skin,trunk,malignant melanoma,NS3
240224892LIMCH1skin,trunk,malignant melanoma,NS3
241223533LDHBskin,trunk,malignant melanoma,NS3
242225067LGI4skin,trunk,malignant melanoma,NS3
2431701812NUP188skin,neck,malignant melanoma,NS3
244222613PTPRCskin,trunk,malignant melanoma,NS3
245224703PTPRDskin,trunk,malignant melanoma,NS3
2461710976PTPRMskin,trunk,malignant melanoma,NS3
247226492PTPN14skin,trunk,malignant melanoma,NS3
24813981PTENskin,trunk,malignant melanoma,NS3
2491699885PTK2Bskin,neck,malignant melanoma,NS3
250142766PTPRSskin,neck,malignant melanoma,NS3
251224038PTPRTskin,trunk,malignant melanoma,NS3
252228836RAB4Askin,trunk,malignant melanoma,NS3
253222702RAB6Cskin,trunk,malignant melanoma,NS3
254227972RAB3Bskin,trunk,malignant melanoma,NS3
255228040QRICH1skin,trunk,malignant melanoma,NS3
256228783PTPRUskin,trunk,malignant melanoma,NS3
257223384PRKCQskin,trunk,malignant melanoma,NS3
258228122PRKACGskin,trunk,malignant melanoma,NS3
2591697480PHF3skin,neck,malignant melanoma,NS3
260223529PIK3C2Gskin,trunk,malignant melanoma,NS3
261223083PGCskin,trunk,malignant melanoma,NS3
262229478ODAMskin,trunk,malignant melanoma,NS3
263222846OSBPL11skin,trunk,malignant melanoma,NS3
264763PIK3CAskin,trunk,malignant melanoma,NS3
265229563PPP4R4skin,trunk,malignant melanoma,NS3
266233169PRDX5skin,neck,malignant melanoma,NS3
2671713461PPP1R16Bskin,trunk,malignant melanoma,NS3
268228913PLCL2skin,trunk,malignant melanoma,NS3
269107459PIK3R4skin,neck,malignant melanoma,NS3
270222870PLCH1skin,trunk,malignant melanoma,NS3
271123827JPH1skin,trunk,malignant melanoma,NS3

Expression for genes affiliated with Giant Congenital Nevus

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Search GEO for disease gene expression data for Giant Congenital Nevus.

Pathways for genes affiliated with Giant Congenital Nevus

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Pathways related to Giant Congenital Nevus according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.1NRAS, MC1R
2
Show member pathways
9.1NRAS, MC1R

Compounds for genes affiliated with Giant Congenital Nevus

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GO Terms for genes affiliated with Giant Congenital Nevus

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Products for genes affiliated with Giant Congenital Nevus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Giant Congenital Nevus

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet