GPHN
MCID: GNT020
MIFTS: 20

Giant Congenital Nevus (GPHN) malady

Rare diseases category

Summaries for Giant Congenital Nevus

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44NIH Rare Diseases, 34MalaCards
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NIH Rare Diseases:44 A congenital giant nevus is a dark-colored, often hairy patch of skin that is present at birth. it is usually smaller in infants and children, but continues to grow with the child. a giant pigmented nevus is usually larger than 20cm in diameter once it stops growing. they are often found on the buttocks, which is known as "bathing trunk" nevi. skin cancer (such as malignant melanoma and other types) may develop in up to 15% (1 out of 6) of people with larger or giant nevi, often in childhood. the risk is higher for larger or giant congenital nevi located on the back or abdomen. last updated: 6/23/2011

MalaCards: Giant Congenital Nevus, also known as giant pigmented hairy nevus, is related to molybdenum cofactor deficiency and melanoma. Affiliated tissues include skin and thyroid.

Aliases & Classifications for Giant Congenital Nevus

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44NIH Rare Diseases, 63UMLS
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


Aliases & Descriptions:

giant congenital nevus 44
giant pigmented hairy nevus 44 63
giant pigmented nevus 44 63
large congenital melanocytic nevus 44
congenital giant pigmented nevus 44
congenital hairy nevus 44
bathing trunk nevus 44
giant hairy nevus 44
gphn 44


Related Diseases for Giant Congenital Nevus

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18GeneCards, 19GeneDecks
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Graphical network of the top 20 diseases related to Giant Congenital Nevus:



Diseases related to giant congenital nevus

Symptoms for Giant Congenital Nevus

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Drugs & Therapeutics for Giant Congenital Nevus

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Giant Congenital Nevus

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Anatomical Context for Giant Congenital Nevus

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34MalaCards
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MalaCards organs/tissues related to Giant Congenital Nevus:

34
Skin, Thyroid

Animal Models for Giant Congenital Nevus or affiliated genes

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Publications for Giant Congenital Nevus

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53PubMed
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Articles related to Giant Congenital Nevus:

(show all 20)
idTitleAuthorsYear
1
Giant congenital nevus associated with papillary thyroid cancer: the first case report. (23968452)
2013
2
Impressive pseudotumoral proliferative nodules in a giant congenital nevus of a newborn. (22958141)
2013
3
A rare association of congenital lumbar hernia and giant congenital nevus. (22648191)
2013
4
Giant congenital nevus with plexiform neurofibroma and malignant peripheral nerve sheath tumor. (22413842)
2012
5
Wells on natural selection: right for the wrong reason--described a giant congenital nevus. (22256630)
2011
6
Images in clinical medicine. Giant congenital nevus. (19726769)
2009
7
Treatment of giant congenital nevus of the back by convergent serial excision. (18837711)
2008
8
Desmoplastic giant congenital nevus with progressive depigmentation. (17097364)
2007
9
A giant congenital nevus spilus in an 8-year-old girl. (17142204)
2006
10
Cutaneous ganglioneuroma within a giant congenital nevus. (24223002)
2005
11
Giant congenital nevus with progressive sclerodermoid reaction in a newborn. (11576407)
2001
12
A newborn with nodular ulcerated lesion on a giant congenital nevus. (10990581)
2000
13
Poliosis associated with a giant congenital nevus. (10411174)
1999
14
Giant congenital nevus. (10829894)
1995
15
Very late metastasis (27 years) of cutaneous malignant melanoma arising in a halo giant congenital nevus. (8075446)
1994
16
Chromosomal findings in cultured melanocytes from a giant congenital nevus. (8330286)
1993
17
Giant congenital nevus and chronic progressive ascending hemiparesis (Mills syndrome). Report of a case. (1624284)
1992
18
Giant congenital nevus and malignant melanoma. (2715664)
1989
19
Giant congenital nevus and melanoma. (3716969)
1986
20
Giant congenital nevus as a basis for the development of malignant melanoma. (4036470)
1985

Variations for Giant Congenital Nevus

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Expression for genes affiliated with Giant Congenital Nevus

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Sources:
16Gene Expression Omnibus DataSets
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Search GEO for disease gene expression data for Giant Congenital Nevus.

Pathways for genes affiliated with Giant Congenital Nevus

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Compounds for genes affiliated with Giant Congenital Nevus

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GO Terms for genes affiliated with Giant Congenital Nevus

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Products for genes affiliated with Giant Congenital Nevus

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Giant Congenital Nevus

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet