GPC
MCID: GNT006
MIFTS: 38

Giant Papillary Conjunctivitis (GPC) malady

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Giant Papillary Conjunctivitis

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Aliases & Descriptions for Giant Papillary Conjunctivitis:

Name: Giant Papillary Conjunctivitis 11 48 13
Conjunctivitis, Giant Papillary 68
 
Conjunctivitis Giant Papillary 50
Gpc 48

Classifications:



External Ids:

Disease Ontology11 DOID:2457
MeSH39 D003233
SNOMED-CT62 231857004
NCIt45 C34507

Summaries for Giant Papillary Conjunctivitis

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MalaCards based summary: Giant Papillary Conjunctivitis, also known as conjunctivitis, giant papillary, is related to papillary conjunctivitis and conjunctivitis. An important gene associated with Giant Papillary Conjunctivitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways are IL4-mediated signaling events and Th2 Differentiation Pathway. Affiliated tissues include eye and neutrophil.

Related Diseases for Giant Papillary Conjunctivitis

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Diseases related to Giant Papillary Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 141)
idRelated DiseaseScoreTop Affiliating Genes
1papillary conjunctivitis10.7
2conjunctivitis10.7
3anterior dislocation of lens10.2CCL11, IL4
4thelaziasis10.2CCL11, IL4
5lymphoblastic leukemia10.2CCL11, IL4
6isthmus cancer10.2CCL11, IL4
7cerebral primitive neuroectodermal tumor10.2CCL11, IL4
8apricot allergy10.2CCL11, IL4
9trachea leiomyoma10.2CCL11, IL4
10visceral steatosis10.2CCL11, IL4
11cutaneous fibrous histiocytoma10.2CCL11, IL4
12lymphocytic gastritis10.2CCL11, IL4
13intravascular angioleiomyoma10.2CCL11, IL4
14latent syphilis10.2CCL11, IL6
15ethmoid sinusitis10.2CCL11, IL4
16inflamed seborrheic keratosis10.2CCL11, IL4
17clostridium difficile colitis10.2IL4, IL6
18barbiturate abuse10.2CCL11, IL4
19childhood malignant mesenchymoma10.2CCL11, IL6
20microglandular adenosis of breast10.2CCL11, CXCL8
21hidradenitis suppurativa10.2CCL11, CXCL8
22gonococcal endophthalmia10.1IL4, IL6
23ectodermal dysplasia bartalos type10.1IL4, IL6
24parkinson disease 1110.1CCL11, CXCL8
25immune-complex glomerulonephritis10.1IL4, IL6
26coenurosis10.1IL4, IL6
27conidiobolomycosis10.1CXCL8, IL4
28hypoparathyroidism-retardation-dysmorphism syndrome10.1IL6, LTF
29red cell phospholipid defect with hemolysis10.1IL4, IL6
30chancroid10.1CXCL8, IL4
31breast intracanalicular fibroadenoma10.1CXCL8, IL4
32orbital osteomyelitis10.1IL4, IL6
33rheumatoid factor-negative juvenile idiopathic arthritis without anti-nuclear antibodies10.1IL6, LTF
34tuberculosis10.1IL4, IL6
35oculomotor nerve paralysis10.1CXCL8, IL6
36common peroneal nerve lesion10.1CXCL8, IL6
37coronary arterial fistulas10.1CXCL8, LTF
38neonatal hypoxic and ischemic brain injury10.1CXCL8, IL6
39thymic neuroendocrine carcinoma10.1CXCL8, IL6
40scleroderma, familial progressive10.1CXCL8, LTF
41schwannoma of ureter10.1CXCL8, IL6
42vernal conjunctivitis10.1
43childhood electroclinical syndrome10.1CXCL8, IL6
44handl syndrome10.1CXCL8, LTF
45labyrinthine bilateral reactive loss10.1CXCL8, IL6
46esophagus lymphoma10.1CXCL8, IL6
47larynx carcinoma in situ10.1CXCL8, IL6
48bullous retinoschisis10.1CXCL8, IL6
49carbuncle10.1CXCL8, IL6
50stomatitis10.1CXCL8, IL6

Graphical network of the top 20 diseases related to Giant Papillary Conjunctivitis:



Diseases related to giant papillary conjunctivitis

Symptoms & Phenotypes for Giant Papillary Conjunctivitis

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Drugs & Therapeutics for Giant Papillary Conjunctivitis

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Drugs for Giant Papillary Conjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 21)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Prednisoloneapproved, vet_approvedPhase 4119350-24-85755
Synonyms:
(11beta)-11,17,21-Trihydroxypregna-1,4-diene-3,20-dione
.DELTA.1-Cortisol
.DELTA.1-Dehydrocortisol
.DELTA.1-Dehydrohydrocortisone
.DELTA.1-Hydrocortisone
.delta.-Cortef
.delta.-Stab
1,2-Dehydrohydrocortisone
1,4-Pregnadiene-11beta,17alpha,21-triol-3,20-dione
1,4-Pregnadiene-3,20-dione-11beta,17alpha,21-triol
1-Dehydrocortisol
1-Dehydrohydrocortisone
3,20-dioxo-11beta,17alpha,21-Trihydroxy-1,4-pregnadiene
46656_FLUKA
46656_RIEDEL
50-24-8
58201-11-9
8056-11-9
AC-1773
AC1L1L2E
Ak-Pred
Ak-Tate
Alphadrol
Articulose-50
BPBio1_000164
BRD-K98039984-001-03-0
BRN 1354103
BSPBio_000148
Bio-0666
Bubbli-Pred
C07369
CCRIS 980
CHEBI:8378
CHEMBL131
CID5755
CO-Hydeltra
CPD000718761
Co-Hydeltra
Codelcortone
Cordrol
Cortalone
Cotogesic
Cotolone
D00472
D011239
DB00860
Decaprednil
Decortin H
Delcortol
Delta F
Delta(1)-dehydrohydrocortisone
Delta-Cortef
Delta-Cortef (TN)
Delta-Ef-Cortelan
Delta-Stab
Delta-stab
Deltacortenol
Deltacortril
Deltacortril Enteric
Deltahydrocortisone
Deltasolone
Deltisilone
Depo-Medrol
Derpo PD
Derpo Pd
Dexa-Cortidelt Hostacortin H
Dexa-Cortidelt hostacortin H
Di Adreson F
Di-Adreson F
Di-Adreson-F
Di-adreson F
DiAdresonF
Dicortol
Donisolone
Dydeltrone
EINECS 200-021-7
Eazolin D
Econopred
Econopred Plus
Erbacort
Erbasona
Estilsona
Fernisolone
Fernisolone P
Fernisolone-P
Flamasone
HMS1568H10
HMS2090J05
HSDB 3385
Hostacortin H
Hydeltra
Hydeltra-Tba
Hydeltrasol
Hydeltrone
Hydrodeltalone
Hydrodeltisone
Hydroretrocortin
Hydroretrocortine
I-Pred
Inflamase Forte
Inflamase Mild
K 1557
Key-Pred
Klismacort
LMST02030179
LS-7669
Lentosone
Lite Pred
M-Predrol
 
MLS001304083
MLS002154250
MLS002207037
Medrol
Medrol Acetate
Metacortandralone
Methylprednisolone Acetate
Meti-Derm
Meticortelone
Metreton
MolPort-002-507-147
NCGC00179649-01
NSC 9120
NSC9120
NSC9900
Neo-Delta-Cortef
Nisolone
Nor-Pred T.B.A.
Ocu-Pred
Ocu-Pred Forte
Ophtho-Tate
Orapred
P0152_SIGMA
P0637
P6004_SIGMA
PRDL
PRED-G
Panafcortelone
Paracortol
Paracotol
Pediapred
Poly-Pred
Precortalon
Precortancyl
Precortilon
Precortisyl
Pred Forte
Pred Mild
Predair
Predair A
Predair Forte
Predalone 50
Predalone T.B.A.
Predate
Predate Tba
Predate-50
Predcor-25
Predcor-50
Predcor-Tba
Predisolone Sodium Phosphate
Predne-Dome
Prednelan
Predni-Dome
Prednicen
Predniliderm
Predniretard
Prednis
Prednisolona
Prednisolona [INN-Spanish]
Prednisolone (JP15/USP/INN)
Prednisolone (anhydrous)
Prednisolone Acetate
Prednisolone Sodium Phosphate
Prednisolone Tebutate
Prednisolone [INN:BAN:JAN]
Prednisolonum
Prednisolonum [INN-Latin]
Predonin
Predonine
Prelone
Prenolone
Prestwick0_000274
Prestwick1_000274
Prestwick2_000274
Prestwick3_000274
Prestwick_404
Rolisone
S1737_Selleck
SAM002264639
SMR000718761
SPBio_002367
Scherisolon
Solone
Steran
Sterane
Sterolone
Supercortisol
UNII-9PHQ9Y1OLM
Ulacort
Ultra Pred
Ultracorten H
Ultracortene H
Ultracortene-H
Ultracortene-Hydrogen
Ultracortene-hydrogen
ZINC03833821
component of Ataraxoid
component of K-Predne-Dome
delta(1)-Cortisol
delta(1)-Dehydrocortisol
delta(1)-Dehydrohydrocortisone
delta(1)-Hydrocortisone
delta(sup 1)-Cortisol
delta(sup 1)-Dehydrocortisol
delta(sup 1)-Dehydrohydrocortisone
delta(sup 1)-Hydrocortisone
delta-dehydrocortisol
delta-dehydrohydrocortisone
delta-hydrocortisone
prednisolone
2
Methylprednisoloneapproved, vet_approvedPhase 4119383-43-26741
Synonyms:
(6S,8S,9S,10R,11S,13S,14S,17R)-11,17-dihydroxy-17-(2-hydroxyacetyl)-6,10,13-trimethyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-3-one
(6a,11b)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6alpha,11beta)-11,17,21-Trihydroxy-6-methylpregna-1,4-diene-3,20-dione
(6α,11β)-11,17,21-trihydroxy-6-methylpregna-1,4-diene-3,20-dione
.DELTA.1-6.alpha.-Methylhydrocortisone
1-Dehydro-6alpha-methylhydrocortisone
1-dehydro-6alpha-Methylhydrocortisone
1-dehydro-6α-methylhydrocortisone
11-beta,17,21-Trihydroxy-6-alpha-methylpregna-1,4-diene-3,20-dione
11beta,17,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methyl-1,4-pregnadiene-3,20-dione
11beta,17alpha,21-Trihydroxy-6alpha-methylpregna-1,4-diene-3,20-dione
121673-01-6
4-08-00-03498 (Beilstein Handbook Reference)
46436_FLUKA
46436_RIEDEL
570-35-4
6 Methylprednisolone
6-Methylprednisolone
6-alpha-Methylprednisolone
6.alpha.-Methylprednisolone
6923-42-8
6alpha-Methyl-11beta,17alpha,21-trihydroxy-1,4-pregnadiene-3,20-dione
6alpha-Methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
6alpha-Methylprednisolone
6alpha-methyl-11beta,17alpha,21-triol-1,4-pregnadiene-3,20-dione
83-43-2
AC1L1N7A
Artisone-Wyeth
Artisone-wyeth
BPBio1_000174
BRD-K35240538-001-03-1
BRN 2340300
BSPBio_000158
Besonia
Bio-0658
CHEBI:6888
CHEMBL650
CID6741
CPD000058330
D00407
D008775
DB00959
Depo-Medrol (acetate)
Dopomedrol
EINECS 201-476-4
Esametone
Firmacort
HMS1568H20
HMS2090B13
HSDB 3127
LMST02030178
LS-118498
Lemod
M0639_SIGMA
M1665
MEPRDL
MLS000028541
MLS001148159
MLS002207191
Medesone
Medixon
Medlone 21
 
Medrate
Medrol
Medrol (TN)
Medrol Adt Pak
Medrol Dosepak
Medrol adt pak
Medrol dosepak
Medrol, Solu-Medrol, Medrone, Methylprednisolone
Medrone
Mesopren
Metastab
Methyleneprednisolone
Methylprednisolon
Methylprednisolone
Methylprednisolone (JP15/USP/INN)
Methylprednisolone [USAN:INN:BAN:JAN]
Methylprednisolone, 6-alpha
Methylprednisolonum
Methylprednisolonum [INN-Latin]
Metilbetasone
Metilprednisolona
Metilprednisolona [INN-Spanish]
Metilprednisolone
Metilprednisolone [DCIT]
Metilprednisolone [Dcit]
Metipred
Metrisone
Metrocort
Metysolon
Moderin
MolPort-002-528-554
NCGC00022735-03
NCI60_001657
NSC-19987
NSC19987
Nirypan
Noretona
Predni N Tablinen
Prednol- L
Pregna-1,4-diene-3,20-dione, 11beta,17,21-trihydroxy-6alpha-methyl- (8CI)
Prestwick0_000279
Prestwick1_000279
Prestwick2_000279
Prestwick3_000279
Prestwick_622
Promacortine
Reactenol
S1733_Selleck
SAM002589984
SMR000058330
SPBio_002377
Sieropresol
Solomet
Summicort
Suprametil
U 7532
UNII-X4W7ZR7023
Urbason
Urbasone
Wyacort
ZINC03875560
delta(1)-6alpha-Methylhydrocortisone
delta(sup 1)-6-alpha-Methylhydrocortisone
methylprednisolone
methylprenisolone
3
LoteprednolapprovedPhase 45382034-46-6, 129260-79-3444025, 9865442
Synonyms:
82034-46-6
AC1L9FKJ
AKOS005145741
Alrex
Alrex, Lotemax, Loteprednol etabonate
CDDD-5604
CHEBI:31784
CHEMBL1200865
CID444025
CPD000469178
D01689
DB00873
HGP-1
HMS2051F16
IDR-90102
IDR-90103
Locort
 
Loteflam
Lotemax
Lotemax (TN)
Loteprednol
Loteprednol Etabonate
Loteprednol etabonate
Loteprednol etabonate (JAN/USAN)
Loteprednolum
Loterox
MLS001424221
MolPort-003-848-424
NCGC00164594-01
P-5604
S1669_Selleck
SAM001246630
SMR000469178
ZINC03920673
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
4Peripheral Nervous System AgentsPhase 423689
5Neuroprotective AgentsPhase 41716
6Methylprednisolone HemisuccinatePhase 41193
7AntiemeticsPhase 44022
8Prednisolone acetatePhase 41193
9Protective AgentsPhase 47443
10Prednisolone phosphatePhase 41193
11Prednisolone hemisuccinatePhase 41193
12Methylprednisolone acetatePhase 41193
13Anti-Inflammatory AgentsPhase 410729
14glucocorticoidsPhase 45103
15Gastrointestinal AgentsPhase 48402
16Autonomic AgentsPhase 410150
17Hormone AntagonistsPhase 413180
18HormonesPhase 414415
19Anti-Allergic AgentsPhase 41522
20Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 413168
21Antineoplastic Agents, HormonalPhase 45592

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%Active, not recruitingNCT01437982Phase 4

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Genetic Tests for Giant Papillary Conjunctivitis

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Anatomical Context for Giant Papillary Conjunctivitis

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MalaCards organs/tissues related to Giant Papillary Conjunctivitis:

36
Eye, Neutrophil

Publications for Giant Papillary Conjunctivitis

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Articles related to Giant Papillary Conjunctivitis:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Filtering bleb-induced giant papillary conjunctivitis. (17826299)
2008
2
Giant papillary conjunctivitis. (18769199)
2008
3
Giant papillary conjunctivitis. (18282547)
2008
4
Tacrolimus ointment 0.03% in the eye for treatment of giant papillary conjunctivitis. (18216583)
2008
5
Immunohistochemical findings in prosthesis-associated giant papillary conjunctivitis. (17760635)
2007
6
M cells are involved in pathogenesis of human contact lens-associated giant papillary conjunctivitis. (17557145)
2007
7
Antibody array-generated cytokine profiles of tears of patients with vernal keratoconjunctivitis or giant papillary conjunctivitis. (16767372)
2006
8
Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses. (15677951)
2005
9
Tear eotaxin levels in giant papillary conjunctivitis associated with ocular prosthesis. (14566648)
2003
10
Contact lens chemistry and giant papillary conjunctivitis. (12772728)
2003
11
Giant papillary conjunctivitis associated with an ocular prosthesis. (12366372)
2001
12
Meibomian gland status and prevalence of giant papillary conjunctivitis in contact lens wearers. (15326900)
2000
13
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study (10844086)
2000
14
Giant papillary conjunctivitis in frequent replacement contact lens wearers: a retrospective study. (10444049)
1999
15
Giant papillary conjunctivitis--a review. (10337425)
1999
16
Role of tear inflammatory mediators in contact lens-associated giant papillary conjunctivitis in soft contact lens wearers. (10410873)
1999
17
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study. (10703125)
1999
18
Effect of lodoxamide on tear leukotriene levels in giant papillary conjunctivitis associated with ocular prosthesis. (9785608)
1998
19
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. (9001768)
1997
20
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I. (9124242)
1997
21
Increased numbers of Langerhans cell and expression of HLA-Dr antigen in the giant papilla of patients with giant papillary conjunctivitis. (8755197)
1996
22
Tear LTC4 levels in patients with subclinical contact lens related giant papillary conjunctivitis. (7586473)
1995
23
Effect of extended wear disposable contact lenses on tear LTC4 in giant papillary conjunctivitis. (22827277)
1995
24
Localised giant papillary conjunctivitis secondary to a dermolipoma. (7556754)
1995
25
Contact lens type, material, and deposits and giant papillary conjunctivitis. (7712614)
1995
26
Giant papillary conjunctivitis. (7886881)
1994
27
Bilateral giant papillary conjunctivitis related to glaucoma drainage surgery blebs. (7995075)
1994
28
N-acetyl-aspartyl glutamic acid (NAAGA) topical eyedrops in the treatment of giant papillary conjunctivitis (GPC). (7910133)
1993
29
Meibomian gland function and giant papillary conjunctivitis. (8420368)
1993
30
Causative factors in unilateral giant papillary conjunctivitis. (8495560)
1993
31
Unusual causes of giant papillary conjunctivitis. (8458237)
1993
32
Safety and efficacy of loteprednol etabonate for treatment of papillae in contact lens-associated giant papillary conjunctivitis. (8319490)
1993
33
Meibomian gland function and giant papillary conjunctivitis. (8420369)
1993
34
Comparison of the clinical performance of the Acuvue disposable contact lens and CSI lens in patients with giant papillary conjunctivitis. (8470716)
1993
35
Evaluation of tear protein deposits on contact lenses from patients with and without giant papillary conjunctivitis. (1499118)
1992
36
Treatment of giant papillary conjunctivitis with cromolyn sodium. (1559288)
1992
37
Giant papillary conjunctivitis and meibomian gland dysfunction blepharitis. (1499122)
1992
38
Daily enzyme cleaning for giant papillary conjunctivitis. (1498575)
1992
39
Meibomian gland function and giant papillary conjunctivitis. (1642294)
1992
40
Continued contact lens wear in patients with giant papillary conjunctivitis. (1904798)
1991
41
Neutrophil chemotactic factors in the tears of giant papillary conjunctivitis patients. (1846131)
1991
42
Eosinophil granule major basic protein in contact lenses of patients with giant papillary conjunctivitis. (2199092)
1990
43
Immunoglobulin deposition on soft contact lenses: relationship to hydrogel structure and mode of use and giant papillary conjunctivitis. (2407379)
1990
44
Giant papillary conjunctivitis. (2193971)
1990
45
Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis. (2196302)
1990
46
Some unusual nonallergic causes of giant papillary conjunctivitis. (2095029)
1990
47
Association of giant papillary conjunctivitis with seasonal allergies. (2320363)
1990
48
Giant papillary conjunctivitis associated with elevated corneal deposits. (1706653)
1990
49
Contact lens induced giant papillary conjunctivitis: a retrospective study. (2708768)
1989
50
HPLC analysis of tear proteins in giant papillary conjunctivitis. (2625085)
1989

Variations for Giant Papillary Conjunctivitis

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Expression for genes affiliated with Giant Papillary Conjunctivitis

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Search GEO for disease gene expression data for Giant Papillary Conjunctivitis.

Pathways for genes affiliated with Giant Papillary Conjunctivitis

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Pathways related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

(show all 34)
idSuper pathwaysScoreTop Affiliating Genes
19.6CCL11, IL4
29.6CCL11, IL4
39.5IL4, IL6
49.5IL4, IL6
59.3CXCL8, IL6
6
Show member pathways
9.3CXCL8, IL6
79.3CXCL8, IL6
89.3CXCL8, IL6
99.3CXCL8, IL6
109.3CXCL8, IL6
119.3CXCL8, IL6
129.3CXCL8, IL6
138.9CXCL8, IL4, IL6
148.9CXCL8, IL4, IL6
15
Show member pathways
8.9CXCL8, IL4, IL6
168.9CXCL8, IL4, IL6
178.7IL4, IL6, IL7
188.7IL4, IL6, IL7
198.7IL4, IL6, IL7
208.7IL4, IL6, IL7
21
Show member pathways
8.7IL4, IL6, IL7
228.7IL4, IL6, IL7
238.5CCL11, CXCL8, IL4, IL6
24
Show member pathways
8.5CCL11, CXCL8, IL4, IL6
25
Show member pathways
8.5CCL11, CXCL8, IL4, IL6
26
Show member pathways
8.5CCL11, CXCL8, IL4, IL6
278.5CCL11, CXCL8, IL4, IL6
28
Show member pathways
7.6CCL11, CXCL8, IL4, IL6, IL7
29
Show member pathways
7.6CCL11, CXCL8, IL4, IL6, IL7
30
Show member pathways
7.6CCL11, CXCL8, IL4, IL6, IL7
317.6CCL11, CXCL8, IL4, IL6, IL7
32
Show member pathways
7.6CCL11, CXCL8, IL4, IL6, IL7
33
Show member pathways
7.6CCL11, CXCL8, IL4, IL6, IL7
34
Show member pathways
7.1CCL11, CXCL8, IL4, IL6, IL7, LTF

GO Terms for genes affiliated with Giant Papillary Conjunctivitis

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Cellular components related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00055767.8CCL11, CXCL8, IL4, IL6, IL7, LTF
2extracellular spaceGO:00056157.1CCL11, CXCL8, IL4, IL6, IL7, LTF

Biological processes related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

(show all 21)
idNameGO IDScoreTop Affiliating Genes
1monocyte chemotaxisGO:000254810.2CCL11, IL6
2defense response to protozoanGO:004283210.2IL4, IL6
3innate immune response in mucosaGO:000222710.2IL4, LTF
4chemokine-mediated signaling pathwayGO:007009810.2CCL11, CXCL8
5defense response to Gram-negative bacteriumGO:005082910.2IL6, LTF
6positive regulation of B cell activationGO:005087110.1IL4, IL6
7neutrophil chemotaxisGO:003059310.1CCL11, CXCL8
8positive regulation of T cell proliferationGO:004210210.0IL4, IL6
9positive regulation of osteoblast differentiationGO:004566910.0IL6, LTF
10positive regulation of tyrosine phosphorylation of STAT proteinGO:004253110.0IL4, IL6
11negative regulation of extrinsic apoptotic signaling pathwayGO:20012379.8IL4, IL7
12positive regulation of B cell proliferationGO:00308909.8IL4, IL7
13positive regulation of T cell differentiationGO:00455829.8IL4, IL7
14chemotaxisGO:00069359.7CCL11, CXCL8, IL4
15cellular response to interleukin-1GO:00713479.7CCL11, CXCL8, IL6
16cellular response to tumor necrosis factorGO:00713569.7CCL11, CXCL8, IL6
17inflammatory responseGO:00069549.6CCL11, CXCL8, IL6
18response to cytokineGO:00340979.5IL4, IL6
19humoral immune responseGO:00069599.3IL6, IL7, LTF
20negative regulation of apoptotic processGO:00430668.8IL4, IL6, IL7, LTF
21immune responseGO:00069558.4CCL11, CXCL8, IL4, IL6, IL7

Molecular functions related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:000800910.1CCL11, CXCL8
2cytokine receptor bindingGO:00051269.8IL4, IL7
3growth factor activityGO:00080838.7IL4, IL6, IL7
4cytokine activityGO:00051258.2CCL11, CXCL8, IL4, IL6, IL7

Sources for Giant Papillary Conjunctivitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
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32ICD9CM
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34KEGG
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41MGI
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67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet