MCID: GNT006
MIFTS: 33

Giant Papillary Conjunctivitis malady

Categories: Rare diseases, Eye diseases

Aliases & Classifications for Giant Papillary Conjunctivitis

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Aliases & Descriptions for Giant Papillary Conjunctivitis:

Name: Giant Papillary Conjunctivitis 10 45 12
Conjunctivitis, Giant Papillary 65
 
Conjunctivitis Giant Papillary 47
Gpc 45

Classifications:



External Ids:

Disease Ontology10 DOID:2457
MeSH36 D003233
SNOMED-CT59 231857004
NCIt42 C34507
UMLS65 C0009769

Summaries for Giant Papillary Conjunctivitis

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MalaCards based summary: Giant Papillary Conjunctivitis, also known as conjunctivitis, giant papillary, is related to gastric cancer and hepatitis. An important gene associated with Giant Papillary Conjunctivitis is CCL11 (C-C Motif Chemokine Ligand 11), and among its related pathways are CXCR3-mediated signaling events and IL4-mediated signaling events. Affiliated tissues include eye, heart and t cells, and related mouse phenotypes are hematopoietic system and immune system.

Related Diseases for Giant Papillary Conjunctivitis

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Diseases related to Giant Papillary Conjunctivitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 143)
idRelated DiseaseScoreTop Affiliating Genes
1gastric cancer10.3
2hepatitis10.3
3prostatitis10.3
4prostate cancer10.2
5leukemia10.2
6amblyopia10.2
7hepatitis c10.2
8papillary carcinoma10.2
9hypertensive encephalopathy10.2CCL11, LTF
10blepharophimosis10.1CCL11, IL5
11cholesteatoma of attic10.1CCL11, IL5
12antley-bixler syndrome with genital anomalies and disordered steroidogenesis10.1CCL11, IL5
13lymphocytic colitis10.1LTF, RNASE3
14trabecular follicular adenocarcinoma10.1IL5, RNASE3
15anus disease10.1LTF, RNASE3
16kyphoscoliotic heart disease10.1IL5, RNASE3
17eosinophilic gastroenteritis10.1CCL11, IL5
18reactive arthritis10.1CCL11, RNASE3
19hepatitis e10.1CCL11, IL5
20status asthmaticus10.1IL5, RNASE3
21keratoconjunctivitis10.1IL5, RNASE3
22benign paroxysmal positional nystagmus10.1IL5, RNASE3
23non specific chronic endometritis10.1IL5, RNASE3
24skin conditions10.1IL5, RNASE3
25hypergonadotropic ovarian failure, familial or sporadic10.1IL5, RNASE3
26central nervous system childhood germ cell tumor10.1CCL11, IL5
27congenital disorder of glycosylation, type ih10.1CCL11, RNASE3
28timothy grass allergy10.1IL5, RNASE3
29neuroblastoma10.1
30colorectal cancer10.1
31reticular dysgenesis10.1
32myocardial infarction10.1
33malaria10.1
34hiv-110.1
35hepatocellular carcinoma10.1
36ehlers-danlos syndrome, type iv10.1
37hepatitis c virus10.1
38multiple myeloma10.1
39phenylketonuria10.1
40prader-willi syndrome10.1
41gitelman syndrome10.1
42retinoschisis10.1
43acute leukemia10.1
44cataract10.1
45diabetic foot ulcers10.1
46glomerulonephritis10.1
47glycogen storage disease10.1
48insulinoma10.1
49lymphoma10.1
50atrial fibrillation10.1

Graphical network of the top 20 diseases related to Giant Papillary Conjunctivitis:



Diseases related to giant papillary conjunctivitis

Symptoms for Giant Papillary Conjunctivitis

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Drugs & Therapeutics for Giant Papillary Conjunctivitis

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Drugs for Giant Papillary Conjunctivitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Loteprednol EtabonatePhase 44482034-46-6444025
Synonyms:
82034-46-6
AC1L9FKJ
AKOS005145741
Alrex
Alrex, Lotemax, Loteprednol etabonate
CDDD-5604
CHEBI:31784
CHEMBL1200865
CID444025
CPD000469178
D01689
DB00873
HGP-1
HMS2051F16
IDR-90102
IDR-90103
 
Locort
Loteflam
Lotemax
Lotemax (TN)
Loteprednol etabonate
Loteprednol etabonate (JAN/USAN)
Loterox
MLS001424221
MolPort-003-848-424
NCGC00164594-01
P-5604
S1669_Selleck
SAM001246630
SMR000469178
ZINC03920673
chloromethyl (8S,9S,10R,11S,13S,14S,17R)-17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthrene-17-carboxylate
chloromethyl 17alpha-[(ethoxycarbonyl)oxy]-11beta-hydroxy-3-oxoandrosta-1,4-diene-17beta-carboxylate
2Anti-Allergic AgentsPhase 41312

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study to Evaluate the Safety and Efficacy of Lotemax Ophthalmic Suspension 0.5%Active, not recruitingNCT01437982Phase 4

Search NIH Clinical Center for Giant Papillary Conjunctivitis

Genetic Tests for Giant Papillary Conjunctivitis

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Anatomical Context for Giant Papillary Conjunctivitis

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MalaCards organs/tissues related to Giant Papillary Conjunctivitis:

33
Eye, Heart, T cells, Brain, Lung, Bone, Monocytes

Animal Models for Giant Papillary Conjunctivitis or affiliated genes

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MGI Mouse Phenotypes related to Giant Papillary Conjunctivitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053977.6CCL11, CMA1, FPR1, IL5, LTF
2MP:00053877.3CCL11, CMA1, FPR1, IL5, LTF

Publications for Giant Papillary Conjunctivitis

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Articles related to Giant Papillary Conjunctivitis:

(show top 50)    (show all 99)
idTitleAuthorsYear
1
Development and analysis of a finite element model to simulate pulmonary emphysema in CT imaging. (26737750)
2015
2
A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting. (24462186)
2014
3
Achondroplasia and brain stem dysfunction. (25040780)
2014
4
Minimal requirements for ubiquitination-mediated regulation of thyroid hormone activation. (25074266)
2014
5
An integrated microfluidic device for rapid serodiagnosis of amebiasis. (24403984)
2013
6
Seven-year increase in exercise systolic blood pressure at moderate workload predicts long-term risk of coronary heart disease and mortality in healthy middle-aged men. (23529164)
2013
7
Prospective study of paclitaxel and irinotecan for elderly patients with unresectable non-small cell lung cancer. (24416995)
2013
8
The involvement of RCAS1 in creating a suppressive tumor microenvironment in patients with pharyngeal squamous cell carcinoma]. (23164108)
2012
9
Development of a short form Social Interaction Anxiety (SIAS) and Social Phobia Scale (SPS) using nonparametric item response theory: the SIAS-6 and the SPS-6. (21744971)
2012
10
Acute promyelocytic leukemia with CD59 deficiency]. (21129240)
2010
11
Granular cell tumor of the suprasternal space. (20860741)
2010
12
Roles of human beta-defensins in innate immune defense at the ocular surface: arming and alarming corneal and conjunctival epithelial cells. (20526610)
2010
13
Antibiotic prophylaxis in vesicoureteral reflux: A paradigm shift. (19468452)
2009
14
Activation of the epithelial sodium channel (ENaC) by serine proteases. (18928407)
2009
15
SERPINB3, apoptosis and autoimmunity. (19332150)
2009
16
Roles of chemokine receptor 4 (CXCR4) and chemokine ligand 12 (CXCL12) in metastasis of hepatocellular carcinoma cells. (18954561)
2008
17
The Bone Morphogenesis Protein-2 (BMP-2) is associated with progression to metastatic disease in gastric cancer. (19688119)
2008
18
An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. (18388311)
2008
19
Interactions among peroxisome proliferator activated receptor-gamma, insulin signaling pathways, and steroidogenic acute regulatory protein in human ovarian cells. (17374711)
2007
20
An age-dependent physiologically based pharmacokinetic/pharmacodynamic model for the organophosphorus insecticide chlorpyrifos in the preweanling rat. (17504771)
2007
21
Impact of CYP2D6 genetic polymorphism on tramadol pharmacokinetics and pharmacodynamics. (17570739)
2007
22
Inositol monophosphatase regulates localization of synaptic components and behavior in the mature nervous system of C. elegans. (17158747)
2006
23
Expression of enzymatically active human granzyme 3 in Escherichia coli for analysis of its substrate specificity. (16405860)
2006
24
The coexistence of the oxidative and reductive systems in roots: the role of plasma membranes. (16154937)
2005
25
Thoracoscopic enucleation of esophageal stromal tumor. (15209752)
2004
26
Interactions amongst plasma retinol-binding protein, transthyretin and their ligands: implications in vitamin A homeostasis and transthyretin amyloidosis. (15588697)
2004
27
Partial trisomy 22 resulting from rearrangements between chromosomes 11/22 and 16/22: a report of two cases. (12892172)
2003
28
Pro- and antioxidant system activity in cervical mucosa]. (12369277)
2002
29
Genes essential for early events in gonadal development. (11301595)
2001
30
Neuropsychiatric features of corticobasal degeneration. (9810944)
1998
31
Antithrombin III (ATIII) replacement therapy in patients with sepsis and/or postsurgical complications: a controlled double-blind, randomized, multicenter study. (9609411)
1998
32
NAG-2, a novel transmembrane-4 superfamily (TM4SF) protein that complexes with integrins and other TM4SF proteins. (9360996)
1997
33
In vitro and in vivo evidence that protein and U1 snRNP nuclear import in somatic cells differ in their requirement for GTP-hydrolysis, Ran/TC4 and RCC1. (8657562)
1996
34
Surfactant suppresses NF-kappa B activation in human monocytic cells. (8600942)
1996
35
Significance of magnesium in congestive heart failure. (8800040)
1996
36
Sublocalization of the human interferon-gamma receptor accessory factor gene and characterization of accessory factor activity by yeast artificial chromosomal fragmentation. (8120065)
1994
37
The Fli-1 proto-oncogene, involved in erythroleukemia and Ewing's sarcoma, encodes a transcriptional activator with DNA-binding specificities distinct from other Ets family members. (8502483)
1993
38
Binding of monomeric human IgG defines an expression polymorphism of Fc gamma RIII on large granular lymphocyte/natural killer cells. (8245476)
1993
39
Mature cystic teratoma of the pancreas: sonographic and CT findings. (8430545)
1993
40
Characterization of the endothelin receptor in primary cultures of human aortic smooth muscle cells. (8107324)
1993
41
Two new human hemoglobin variants caused by unusual mutational events: Hb Zaire contains a five residue repetition within the alpha- chain and Hb Duino has two residues substituted in the beta-chain. (1511986)
1992
42
Cutaneous T-cell lymphoma (parapsoriasis en plaque). An association with pityriasis lichenoides et varioliformis acuta in young children. (2241197)
1990
43
Developmental expression of proteolipid protein and DM20 mRNAs and proteins in the rat brain. (1705207)
1990
44
AIDS dementia complex, competency to informed consent, risk assessment, and the ADC defense. (11650316)
1989
45
Adult Turner syndrome associated with chylous ascites and vascular anomalies. (3594929)
1987
46
Left ventricular thrombosis and cerebrovascular accident in acute myocardial infarction. (6721949)
1984
47
Radiographic tracheal diameter measurements in acute infectious croup: an objective scoring system. (7021067)
1981
48
Hematology problem: sideroblastic anemia secondary to alcoholism. (7315863)
1981
49
Superimposedan abruptio placentae, hypofibrinogenemia, acute renal shutdown, and paralytic ileus complicating a case of prepregnancy hypertension. (13810460)
1959
50

Variations for Giant Papillary Conjunctivitis

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Expression for genes affiliated with Giant Papillary Conjunctivitis

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Search GEO for disease gene expression data for Giant Papillary Conjunctivitis.

Pathways for genes affiliated with Giant Papillary Conjunctivitis

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GO Terms for genes affiliated with Giant Papillary Conjunctivitis

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Biological processes related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:00069558.6CCL11, CMA1, IL5

Sources for Giant Papillary Conjunctivitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet