MCID: GNT006
MIFTS: 33

Giant Papillary Conjunctivitis malady

Rare diseases category

Aliases & Classifications for Giant Papillary Conjunctivitis

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Giant Papillary Conjunctivitis, Aliases & Descriptions:

Name: Giant Papillary Conjunctivitis 9 41
Conjunctivitis, Giant Papillary 60
 
Conjunctivitis Giant Papillary 43
Gpc 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases


External Ids:

Disease Ontology9 DOID:2457
MeSH33 D003233
SNOMED-CT55 231857004
NCIt38 C34507

Summaries for Giant Papillary Conjunctivitis

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MalaCards based summary: Giant Papillary Conjunctivitis, also known as conjunctivitis, giant papillary, is related to vernal keratoconjunctivitis and conjunctivitis. An important gene associated with Giant Papillary Conjunctivitis is CCL11 (chemokine (C-C motif) ligand 11), and among its related pathways are Allograft rejection and Chemokine Signaling. The compounds ltc4 and pgd2 have been mentioned in the context of this disorder. Affiliated tissues include eye and neutrophil, and related mouse phenotypes are immune system and respiratory system.

Related Diseases for Giant Papillary Conjunctivitis

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Graphical network of the top 20 diseases related to Giant Papillary Conjunctivitis:



Diseases related to giant papillary conjunctivitis

Symptoms for Giant Papillary Conjunctivitis

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Drugs & Therapeutics for Giant Papillary Conjunctivitis

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Drug clinical trials:

Search ClinicalTrials for Giant Papillary Conjunctivitis

Search NIH Clinical Center for Giant Papillary Conjunctivitis

Genetic Tests for Giant Papillary Conjunctivitis

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Anatomical Context for Giant Papillary Conjunctivitis

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MalaCards organs/tissues related to Giant Papillary Conjunctivitis:

31
Eye, Neutrophil

Animal Models for Giant Papillary Conjunctivitis or affiliated genes

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MGI Mouse Phenotypes related to Giant Papillary Conjunctivitis:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053878.5CCL11, CCL24, PRG2
2MP:00053888.4CCL11, CCL24, PRG2
3MP:00053978.2CCL11, CCL24, PRG2

Publications for Giant Papillary Conjunctivitis

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Articles related to Giant Papillary Conjunctivitis:

(show top 50)    (show all 97)
idTitleAuthorsYear
1
Giant papillary conjunctivitis. (18769199)
2008
2
Filtering bleb-induced giant papillary conjunctivitis. (17826299)
2008
3
Antibody array-generated cytokine profiles of tears of patients with vernal keratoconjunctivitis or giant papillary conjunctivitis. (16767372)
2006
4
Conjunctival cytology features of giant papillary conjunctivitis associated with ocular prostheses. (15677951)
2005
5
Contact lens chemistry and giant papillary conjunctivitis. (12772728)
2003
6
Tear eotaxin levels in giant papillary conjunctivitis associated with ocular prosthesis. (14566648)
2003
7
Giant papillary conjunctivitis associated with an ocular prosthesis. (12366372)
2001
8
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study (10844086)
2000
9
Giant papillary conjunctivitis in frequent-replacement contact lens wearers: a retrospective study. (10703125)
1999
10
Giant papillary conjunctivitis--a review. (10337425)
1999
11
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. The Loteprednol Etabonate Giant Papillary Conjunctivitis Study Group I. (9124242)
1997
12
A double-masked, placebo-controlled evaluation of the efficacy and safety of loteprednol etabonate in the treatment of giant papillary conjunctivitis. (9001768)
1997
13
Increased numbers of Langerhans cell and expression of HLA-Dr antigen in the giant papilla of patients with giant papillary conjunctivitis. (8755197)
1996
14
Bilateral giant papillary conjunctivitis related to glaucoma drainage surgery blebs. (7995075)
1994
15
Causative factors in unilateral giant papillary conjunctivitis. (8495560)
1993
16
Comparison of the clinical performance of the Acuvue disposable contact lens and CSI lens in patients with giant papillary conjunctivitis. (8470716)
1993
17
N-acetyl-aspartyl glutamic acid (NAAGA) topical eyedrops in the treatment of giant papillary conjunctivitis (GPC). (7910133)
1993
18
Unusual causes of giant papillary conjunctivitis. (8458237)
1993
19
Meibomian gland function and giant papillary conjunctivitis. (8420368)
1993
20
Giant papillary conjunctivitis and meibomian gland dysfunction blepharitis. (1499122)
1992
21
Neutrophil chemotactic factors in the tears of giant papillary conjunctivitis patients. (1846131)
1991
22
Continued contact lens wear in patients with giant papillary conjunctivitis. (1904798)
1991
23
Human conjunctival mast cells: distribution of MCT and MCTC in vernal conjunctivitis and giant papillary conjunctivitis. (2196302)
1990
24
Giant papillary conjunctivitis. (2193971)
1990
25
Some unusual nonallergic causes of giant papillary conjunctivitis. (2095029)
1990
26
Protein and elemental analysis of contact lenses of patients with superior limbic keratoconjunctivitis or giant papillary conjunctivitis. (2717140)
1989
27
Conjunctival deposition of eosinophil granule major basic protein in vernal keratoconjunctivitis and contact lens-associated giant papillary conjunctivitis. (2750834)
1989
28
Immune responses in monkeys to lenses from patients with contact lens induced giant papillary conjunctivitis. (2917401)
1989
29
Contact lens induced giant papillary conjunctivitis: a retrospective study. (2708768)
1989
30
HPLC analysis of tear proteins in giant papillary conjunctivitis. (2625085)
1989
31
Giant papillary conjunctivitis associated with rigid gas permeable contact lenses. (3208429)
1988
32
Giant papillary conjunctivitis. (3053490)
1988
33
A review of contact lens induced giant papillary conjunctivitis. (3336050)
1988
34
Giant papillary conjunctivitis. (3949453)
1986
35
Giant papillary conjunctivitis from an exposed prolene suture. (3756614)
1986
36
Suture barb giant papillary conjunctivitis. (6709289)
1984
37
Tear immunoglobulins in giant papillary conjunctivitis induced by contact lenses. (6702985)
1984
38
Giant papillary conjunctivitis in connection with corneoscleral supramid (nylon) suture knots. (6720279)
1984
39
Transient ptosis secondary to giant papillary conjunctivitis in a hydrogel lens patient. (6643895)
1983
40
Clinical aspects of giant papillary conjunctivitis. (7339618)
1981
41
Percentage of degranulated mast cells in vernal conjunctivitis and giant papillary conjunctivitis associated with contact-lens wear. (7234932)
1981
42
Giant papillary conjunctivitis after keratoplasty. (7008616)
1981
43
An immunopathologic study of giant papillary conjunctivitis associated with an ocular prosthesis. (7294096)
1981
44
Giant papillary conjunctivitis. (7239822)
1981
45
Giant papillary conjunctivitis with ocular prostheses. (7362515)
1980
46
Giant papillary conjunctivitis: an overview. (448014)
1979
47
Giant papillary conjunctivitis and ptosis in a contact lens wearer. (458521)
1979
48
Vernal conjunctivitis and contact lens-associated giant papillary conjunctivitis compared and contrasted. (443320)
1979
49
Surface morphology of giant papillary conjunctivitis in contact lens wearers. (623198)
1978
50
Giant papillary conjunctivitis induced by hard or soft contact lens wear: quantitative histology. (714378)
1978

Variations for Giant Papillary Conjunctivitis

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Expression for genes affiliated with Giant Papillary Conjunctivitis

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Search GEO for disease gene expression data for Giant Papillary Conjunctivitis.

Pathways for genes affiliated with Giant Papillary Conjunctivitis

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Compounds for genes affiliated with Giant Papillary Conjunctivitis

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Compounds related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

(show all 16)
idCompoundScoreTop Affiliating Genes
1ltc4439.6PRG2, CCL11
2pgd2439.6CCL11, PRG2
3methacholine43 49 1211.6CCL11, PRG2
4allergens439.5CCL11, PRG2
5fmlp439.4CCL11, PRG2
6indomethacin43 28 59 1212.3CCL11, PRG2
7heparin43 28 24 1212.3CCL11, PRG2
8tarc439.3CCL11, CCL24
9ccl343 2810.2CCL24, CCL11
10rantes439.1CCL24, CCL11
11genistein43 28 59 2 24 1214.0CCL11, PRG2
12histamine43 28 2410.8CCL11, CCL24, PRG2
13actinomycin d438.8PRG2, CCL24, CCL11
14superoxide43 249.8CCL11, CCL24, PRG2
15oxygen43 249.7CCL11, CCL24, PRG2
16calcium43 49 24 1211.4PRG2, CCL24, CCL11

GO Terms for genes affiliated with Giant Papillary Conjunctivitis

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Biological processes related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

(show all 11)
idNameGO IDScoreTop Affiliating Genes
1eosinophil chemotaxisGO:00482459.3CCL24, CCL11
2positive regulation of Rac GTPase activityGO:00328559.2CCL24, CCL11
3positive regulation of actin filament polymerizationGO:00308389.2CCL11, CCL24
4positive regulation of endothelial cell proliferationGO:00019389.2CCL11, CCL24
5positive regulation of angiogenesisGO:00457669.1CCL24, CCL11
6cytoskeleton organizationGO:00070109.1CCL24, CCL11
7regulation of cell shapeGO:00083609.0CCL11, CCL24
8inflammatory responseGO:00069549.0CCL24, CCL11
9chemotaxisGO:00069358.9CCL24, CCL11
10positive regulation of cell migrationGO:00303358.7CCL24, CCL11
11immune responseGO:00069558.7PRG2, CCL24, CCL11

Molecular functions related to Giant Papillary Conjunctivitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1chemokine activityGO:00080099.0CCL11, CCL24

Products for genes affiliated with Giant Papillary Conjunctivitis

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  • Antibodies
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  • Kits and Assays

Sources for Giant Papillary Conjunctivitis

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet