MCID: GNG012
MIFTS: 52

Gingival Overgrowth malady

Categories: Gastrointestinal diseases, Oral diseases

Aliases & Classifications for Gingival Overgrowth

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Aliases & Descriptions for Gingival Overgrowth:

Name: Gingival Overgrowth 11 26 49 38 13
Gingival Enlargement Nos 11
 
Gingival Enlargement 11
Gingival Hyperplasia 67

Classifications:



External Ids:

Disease Ontology11 DOID:3086
ICD1029 K06.1
MeSH38 D019214

Summaries for Gingival Overgrowth

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Wikipedia:70 Gingival enlargement, (also termed gingival overgrowth, hypertrophic gingivitis, gingival hyperplasia,... more...

MalaCards based summary: Gingival Overgrowth, also known as gingival enlargement nos, is related to fibromatosis, gingival, 1 and gingivitis. An important gene associated with Gingival Overgrowth is MMP1 (Matrix Metallopeptidase 1), and among its related pathways are Syndecan-1-mediated signaling events and Immune response_Oncostatin M signaling via JAK-Stat in human cells. Affiliated tissues include heart, kidney and liver, and related mouse phenotypes are digestive/alimentary and respiratory system.

Related Diseases for Gingival Overgrowth

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Diseases related to Gingival Overgrowth via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 94)
idRelated DiseaseScoreTop Affiliating Genes
1fibromatosis, gingival, 132.1CD36, MMP1, TGFB1
2gingivitis31.4IL1A, IL6, TGFB1, TIMP1
3keloids29.6IL6, MMP3, TIMP1
4amelogenesis imperfecta, type ig11.1
5epulis10.8
6scrotum paget's disease10.6IL6, TGFB1
7lymphogranuloma venereum10.6CTGF, TGFB1
8vibrio vulnificus infection10.5IL6, TGFB1
9hypohidrosis10.5CTGF, TGFB1
10stomatitis10.5CTGF, TGFB1
11post-infectious myocarditis10.5IL6, TGFB1
12acromicric dysplasia10.5CTGF, TGFB1
13periodontitis10.5
14diamond-blackfan anemia10.4PDGFB, TGFB1
15autoimmune polyendocrine syndrome10.4CD36, IL6
16alopecia areata10.4CD36, DCN
17osteogenesis imperfecta, type x10.4IL6, MMP1
18congenital methemoglobinemia10.4CD36, IL6, TGFB1
19keratopathy10.3CD36, MMP1, TGFB1
20epstein-barr virus hepatitis10.3IL1A, IL6
21renal oncocytoma10.3CTGF, IL6, TGFB1
22burn scar10.3IL6, TGFB1, TIMP1
23epidermolysis bullosa simplex superficialis10.3CD36, CTGF, TGFB1
24small intestine cancer, childhood10.3MMP1, MMP3
25lymphedema10.3IL6, TGFB1, TIMP1
26optic atrophy 710.3IL1A, MMP1
27pathological gambling10.3MMP1, MMP3
28paranasal sinus sarcoma10.3CTGF, TGFB1, TIMP1
29mastoiditis10.3IL6, MMP1, TIMP1
30gemistocytic astrocytoma10.3IL6, TGFB1, TIMP1
31exudative vitreoretinopathy 110.3CTGF, TGFB1, TIMP1
32congenital chloride diarrhea10.3MMP1, MMP3
33juvenile astrocytoma10.2MMP1, MMP3
34vitreous abscess10.2CTGF, PDGFB, TGFB1
35prostate leiomyosarcoma10.2IL6, MMP3
36pauciarticular onset juvenile idiopathic arthritis10.2CD36, DCN, MMP1
37orbital lymphangioma10.2IL1A, IL6, TGFB1
38retroperitoneal fibrosis10.2IL1A, IL6, TGFB1
39immunodeficiency 27b, mycobacteriosis, ad10.2MMP3, TIMP1
40asbestosis10.2IL1A, IL6, TGFB1
41twin-to-twin transfusion syndrome10.1DCN, TGFB1
42lymphangioma10.1IL1A, IL6, MMP1
43retinal degeneration10.1MMP1, MMP3
44sterility due to immotile flagella10.1IL1A, IL6
45osteopetrosis10.1CD36, TGFB1
46periodic paralyses10.1IL1A, IL6
47familial nephrotic syndrome10.1MMP1, MMP3
48third cranial nerve disease10.0IL1A, IL6, MMP1
49malignant giant cell tumor10.0IL6, MMP1, MMP3
50schwannomatosis10.0MMP3, TIMP1

Graphical network of the top 20 diseases related to Gingival Overgrowth:



Diseases related to gingival overgrowth

Symptoms for Gingival Overgrowth

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Drugs & Therapeutics for Gingival Overgrowth

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Drugs for Gingival Overgrowth (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Tacrolimusapproved, investigationalPhase 41074104987-11-3445643, 439492
Synonyms:
(-)-FK 506
(3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26aS)-5,19-dihydroxy-3-{(1E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl}-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(prop-2-en-1-yl)-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-3H-15,19-epoxypyrido[2,1-c][1,4]oxazacyclotricosine-1,7,20,21(4H,23H)-tetrone
104987-11-3
109581-93-3 (Hydrate)
15,19-epoxy-3H-pyrido[2,1-c][1,4]oxaazacyclotricosine-1,7,20,21(23H)-tetrone,
3S-[3R*[E(1S*,3S*,4S*)],4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26aR*]]-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5, 19-dihydroxy-3-[2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl]-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-propenyl)-15,19-epoxy-3H-pyrido[2,1-c] [1,4] oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone
8-DEETHYL-8-[BUT-3-ENYL]-ASCOMYCIN
AC-1182
AC1L1K7H
AC1L97GB
AC1L9IBU
AKOS005145901
Advagraf
Ambap104987-11-3
Ambap5429
Anhydrous tacrolimus
BCBcMAP01_000194
BRD-K35452788-001-02-1
BSPBio-001279
BSPBio_001279
Bio-0921
Bio2_000470
Bio2_000950
C01375
C44H69NO10
CCRIS 7124
CHEBI:100924
CHEBI:61049
CHEMBL1200738
CID11158639
CID11556866
CID439492
CID445643
CID5372
CID5472317
CID6426916
CID6436007
CID6473866
CID6536850
CID6610362
CID6912836
CID9832283
CID9853905
CID9918805
CID9940643
CID9963169
CPD-10016
CPD000466356
D08556
DB00864
DivK1c_001040
FK 506
FK-506
FK5
FK506
FR 900506
FR-900506
 
FR900506
FT-0082660
Fk-506
Fujimycin
Graceptor
HMS1362O21
HMS1792O21
HMS1990O21
HMS2051C18
HMS2093M19
HMS503O21
IDI1_001040
IDI1_002225
K506
KBio1_001040
KBio2_000619
KBio2_003187
KBio2_005755
KBio3_001097
KBio3_001098
KBioGR_000619
KBioSS_000619
L 679934
L-679934
LCP-Tacro
LMPK04000003
LS-64247
MLS000759471
MLS001424054
Modigraf
MolPort-003-666-518
NCGC00163470-01
NCGC00163470-02
NCGC00163470-03
NCGC00163470-04
NCGC00179232-01
NChemBio.2007.16-comp1
NINDS_001040
NSC717865
Prograf
Prograf (TN)
Protopic
Protopy
S5003_Selleck
SAM001246677
SMR000466356
Tacarolimus
Tacrolimus (INN)
Tacrolimus (Prograf?)
Tacrolimus (anhydrous)
Tacrolimus anhydrous
Tacrolimus hydrate
Tacrolimus, anhydrous
Tsukubaenolide
UNII-Y5L2157C4J
nchembio.2007.23-comp2
tacrolimus
tacrolimus hydrate
2
Cyclosporineapproved, investigational, vet_approvedPhase 491579217-60-0, 59865-13-35284373, 6435893
Synonyms:
1c5f
1cyn
30024_FLUKA
30024_SIGMA
59865-13-3
79217-60-0
AC1L1EQW
AC1NQXJE
AC1NR4C4
AC1NUQK3
AC1NUZNC
AC1O5KOG
AC1Q2UDG
Ambap59865-13-3
Ambotz59865-13-3
Antibiotic S 7481F1
BMT-ABA-SAR-MLE-VAL-MLE-ALA-ALA-MLE-MLE-MVA
BMT-ABA-SAR-MLE-VAL-MLE-ALA-DAL-MLE-MLE-MVA
BPBio1_000496
BRD-A64290322-001-01-6
BRD-A69815203-001-04-3
BRD-K13533483-001-03-0
BSPBio_000450
BSPBio_001596
BSPBio_003186
C 3662
C05086
C1832_SIGMA
C3662_SIGMA
C62H111N11O12
CB-01-09 MMX
CHEBI:106343
CHEBI:328305
CHEBI:4031
CHEMBL160
CHEMBL386389
CHEMBL532318
CID2909
CID5280754
CID5284373
CID5458585
CID5497195
CID6435893
CSA
CYCLOSPORIN A (SEE ALSO TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A))
CYCLOSPORIN A, USP
Ciclosporin
Ciclosporin (JP15)
Ciclosporina
Ciclosporine
Ciclosporinum
Cipol N
Cipol-N
Consupren
Consupren S
CsA
CsA & IFN.alpha.
CyA
Cyclokat
Cyclosporin
Cyclosporin A
Cyclosporin A & IFN.alpha.
Cyclosporin A Implant
Cyclosporin A, Tolypocladium inflatum
Cyclosporine (USP)
Cyclosporine A
Cyclosporine [USAN]
D00184
DE-076
DivK1c_000871
EU-0100242
Equoral
GNF-Pf-2808
Gengraf
Gengraf (TN)
HMS1569G12
HMS1791P18
HMS1921L20
HMS1989P18
HMS2089A09
HMS2092F06
HMS502L13
Helv Chim Acta 60: 1568 (1977)
 
I06-0379
I06-0966
IDI1_000871
KBio1_000871
KBio2_000780
KBio2_003348
KBio2_005916
KBio3_002686
KBioGR_001898
KBioSS_000780
LMPK14000003
LS-257
LS-58836
Lopac0_000242
MLS000028376
MLS001333756
MLS002153454
MLS002207033
Mitogard
Modusik-A
MolPort-000-760-988
MolPort-005-934-008
MolPort-006-705-994
NCGC00093704-01
NCGC00093704-02
NCGC00093704-03
NCGC00093704-04
NCGC00093704-05
NCGC00093704-06
NCGC00093704-07
NCGC00093704-08
NCGC00164258-01
NCGC00164258-02
NINDS_000871
NSC290193
Neoplanta
Neoral
Neoral (TN)
NeuroSTAT
Nova-22007
OL 27-400
OL-27400
OLO-400
Papilock
Prestwick2_000435
Prestwick3_000435
Prestwick_731
Pulminiq
Ramihyphin A
Restasis
Restasis (TN)
S-Neoral
S1514_Selleck
SDZ-OXL 400
SMR000058578
SPBio_001467
SPECTRUM1502202
ST-603
Sandimmun
Sandimmun Neoral
Sandimmune
Sandimmune (TN)
Sandimmune, Gengraf, Restasis, Atopica, Sangcya, Cyclosporine
Sang-2000
Sang-35
SangCyA
Sangcya
Sigmasporin
Sigmasporin Microoral
Spectrum2_001484
Spectrum3_001593
Spectrum4_001279
Spectrum5_001628
Spectrum_000300
TRANSGENIC MODEL EVALUATION (CYCLOSPORIN A)
Vekacia
Zyclorin
cyclophorine
cyclosporin A
cyclosporine
from Tolypocladium inflatum (Trichoderma polysporin)
nchembio.184-comp6
nchembio.301-comp5
nchembio.342-comp1
3
Miconazoleapproved, investigational, vet_approvedPhase 4362422916-47-84189
Synonyms:
(+-)-1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-Dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl)imidazole
1-(2,4-dichloro-beta-((2,4-dichlorobenzyl)oxy)phenethyl) imidazole
1-[2,4-Dichloro- beta-([2,4-dichloro- benzyl]oxy)phenethyl]imidazole
1-[2-(2,4-Dichloro-benzyloxy)-2-(2,4-dichloro-phenyl)-ethyl]-1H-imidazole
1-[2-(2,4-Dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]-1H-imidazole
1-[2-(2,4-dichlorobenzyloxy)-2-(2,4-dichlorophenyl)ethyl]-1H-imidazole
1-[2-(2,4-dichlorophenyl)-2-[(2,4-dichlorophenyl)methoxy]ethyl]imidazole
1-[2-(2,4-dichlorophenyl)-2-{[(2,4-dichlorophenyl)methyl]oxy}ethyl]-1H-imidazole
1-{2-[(2,4-dichlorobenzyl)oxy]-2-(2,4-dichlorophenyl)ethyl}-1H-imidazole
22832-87-7 (NITRATE)
22916-47-8
75319-47-0
AB00053500
AC1L1HM1
AKOS001574474
Aflorix(nitrate)
Albistat(nitrate)
Andergin(nitrate)
BPBio1_000279
BRD-A82396632-001-03-0
BRD-A82396632-008-02-7
BRN 0965511
BSPBio_000253
BSPBio_002033
CCRIS 7924
CHEBI:6923
CHEMBL91
CID4189
CPD-4501
Conofite(nitrate)
D00416
DB01110
Dactarin
Daktarin IV
Daktarin iv
DivK1c_000156
EINECS 245-324-5
Epi-Monistat(nitrate)
Femizol-M
Florid(nitrate)
Gyno-Daktar(nitrate)
HMS1568M15
HMS2090B21
I14-14342
IDI1_000156
Imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl)methoxy)ethyl)- (9CI)
KBio1_000156
KBio2_001445
KBio2_004013
KBio2_006581
KBio3_001533
KBioGR_000581
KBioSS_001445
LS-78378
Lotrimin AF(nitrate)
MCZ
MJR 1762
MLS002222203
Micantin (nitrate)
Miconasil Nitrate
 
Miconazol
Miconazol [INN-Spanish]
Miconazole
Miconazole (JP15/USP/INN)
Miconazole 3
Miconazole 3 Combination Pack
Miconazole 7 Combination Pack
Miconazole [USAN:BAN:INN:JAN]
Miconazole nitrate salt
Miconazole-7
Miconazolo
Miconazolo [DCIT]
Miconazolum
Miconazolum [INN-Latin]
Micozole
Minostate
MolPort-002-557-553
Monazole 7
Monista (nitrate)
Monistat
Monistat (TN)
Monistat 1 Combination Pack
Monistat 3 Dual-Pak
Monistat 3 Vaginal Ovules
Monistat 5 Tampon
Monistat 7 Dual-Pak
Monistat 7 Vaginal Suppositories
Monistat Dual- PAK
Monistat IV
Monistat iv (TN)
Monistat iv (tn)
Monistat-Derm
NCI60_001353
NCI60_001380
NINDS_000156
NSC 170986
NSC169434
NSC170986
Novo-Miconazole Vaginal Ovules
Oprea1_091955
Prestwick0_000067
Prestwick1_000067
Prestwick2_000067
Prestwick3_000067
Prestwick_335
R 18134
R-14,889
SMR001307249
SPBio_000976
SPBio_002174
STK834405
STOCK1S-93556
Spectrum2_001048
Spectrum3_000507
Spectrum4_000061
Spectrum5_001297
Spectrum_000965
UNII-7NNO0D7S5M
Vusion
Zimycan
imidazole, 1-(2-(2,4-dichlorophenyl)-2-((2,4-dichlorophenyl) methoxy)ethyl)- (9CI)
miconazole
4Calcineurin InhibitorsPhase 41597
5Antifungal AgentsPhase 43615
6Immunosuppressive AgentsPhase 412770
7Anti-Infective AgentsPhase 4, Phase 221402
8Dermatologic AgentsPhase 4, Phase 25674
9Antirheumatic AgentsPhase 410627
10
Phenytoinapproved, vet_approvedPhase 37657-41-01775
Synonyms:
125-59-7
2,4-Imidazolidinedione, 5,5-diphenyl- (9CI)
2-hydroxy-5,5-diphenyl-3,5-dihydro-4H-imidazol-4-one
5,5-DIPHENYLHYDANTOIN
5,5-Diphenyl-2,4-imidazolidinedione
5,5-Diphenyl-imidazolidine-2,4-dione
5,5-Diphenylhydantoin
5,5-Diphenylhydantoin (IUPAC)
5,5-Diphenylhydantoin (phenytoin)
5,5-Diphenylimidazolidin-2,4-dione
5,5-Diphenyltetrahydro-1H-2,4-imidazoledione
5,5-Dwufenylohydantoina
5,5-Dwufenylohydantoina [Polish]
5,5-diphenylhydantoin
5,5-diphenylimidazolidine-2,4-dione
5,5-diphenyltetrahydro-1H-2,4-imidazoledione
57-41-0
630-93-3
AC-376
AC1L1C7L
AC1Q6G55
AC1Q6G56
AI3-52498
AKOS000416887
AKOS003245432
Aleviatin
Antisacer
Auranile
BAS 00281572
BIDD:GT0625
BIDD:PXR0090
BRD-K55930204-001-02-7
BSPBio_001437
Bio-0370
C07443
CCRIS 515
CHEBI:8107
CHEMBL16
CID1775
CL12003
Causoin
Citrullamon
Citrulliamon
Comital
Comitoina
Convul
D 4007
D00512
D0894
D4007_SIGMA
DB00252
DILANTIN-30
DPH
DPH (VAN)
Danten
Dantinal
Dantoinal
Dantoinal klinos
Dantoine
Denyl
Di-Hydan
Di-Lan
Di-Lan (VAN)
Di-Phetine
Didan TDC 250
Didan-tdc-250
Difenilhidantoina
Difenilhidantoina [Spanish]
Difenin
Difetoin
Difhydan
Dihycon
Dihydan toin
Dihydantoin
Dilabid
Dilantin
Dilantin (TN)
Dilantin acid
Dilantin-125
Dilantine
Dillantin
Dintoin
Dintoina
Diphantoin
Diphedal
Diphedan
Diphenat
Diphenin
Diphenine
Diphentoin
Diphentyn
Diphenylan
Diphenylan Sodium
Diphenylhydantoin
Diphenylhydantoin (VAN)
Diphenylhydantoine
Diphenylhydantoine [French]
Diphenylhydatanoin
Ditoinate
DivK1c_000507
EINECS 200-328-6
EU-0100378
Ekko
Ekko capsules
Elepsindon
Enkelfel
Epamin
Epanutin
Epasmir "5"
Epasmir 5
Epdantoin Simple
Epdantoine simple
Epelin
Epifenyl
Epihydan
Epilan
Epilan D
Epilan-D
Epilantin
Epinat
Epised
Eptal
Eptoin
Extended Phenytoin Sodium
Fenantoin
Fenantoin Mn Pharma
Fenidantoin "s"
Fenidantoin s
Fenitoin
Fenitoina
Fenitoina [INN-Spanish]
Fentoin
Fenylepsin
Fenytoin Dak
Fenytoine
Gerot-epilan-D
HMS1412J16
 
HMS1694O05
HMS1791H19
HMS1989H19
HMS2089E11
Hidan
Hidantal
Hidantilo
Hidantina
Hidantina senosian
Hidantina vitoria
Hidantomin
Hindatal
Hydantal
Hydantin
Hydantoin
Hydantoin, 5,5-diphenyl- (8CI)
Hydantoinal
Hydantol
I14-6452
IDI1_000507
IDI1_008433
IFLab1_000214
Ictalis simple
Idantoil
Idantoin
InChI=1/C15H12N2O2/c18-13-15(17-14(19)16-13,11-7-3-1-4-8-11)12-9-5-2-6-10-12/h1-10H,(H2,16,17,18,19
Iphenylhydantoin
KBio1_000507
KBio2_001585
KBio2_004153
KBio2_006721
KBio3_001780
KBioGR_001387
KBioSS_001585
Kessodanten
LS-34
Labopal
Lehydan
Lepitoin
Lepsin
Lopac-D-4007
Lopac0_000329
Lopac0_000378
MLS000069789
MLS001074087
MLS002454401
Mesantoin
Minetoin
MolPort-001-785-683
MolPort-002-365-712
MolPort-004-876-351
NCGC00015342-01
NCGC00015342-02
NCGC00015342-04
NCGC00021139-01
NCGC00091492-01
NCGC00091492-02
NCGC00091492-03
NCGC00091492-04
NCGC00091492-05
NCGC00093810-01
NCGC00093810-02
NCI-C55765
NINDS_000507
NSC 8722
NSC8722
Neos-Hidantoina
Neosidantoina
Novantoina
Novophenytoin
Om hidantoina simple
Om-Hydantoine
Oprea1_373280
Oxylan
PHENYTEK
PHENYTOIN (5,5-DIPHENYLHYDANTOIN)
PHENYTOIN SODIUM, EXTENDED
Phanantin
Phanatine
Phenatine
Phenatoine
Phenhydan
Phenhydanin
Phenitoin
Phentoin
Phentytoin
Phenytex
Phenytoin (JP15/USP/INN)
Phenytoin AWD
Phenytoin Sodium
Phenytoin [USAN:INN:BAN:JAN]
Phenytoin-Gerot
Phenytoine
Phenytoine [INN-French]
Phenytoinum
Phenytoinum [INN-Latin]
Prompt Phenytoin Sodium
Ritmenal
SMR000059026
SPBio_001281
STK058029
STK182871
Saceril
Sanepil
Silantin
Sinergina
Sodanthon
Sodantoin
Sodanton
Sodium Diphenylhydantoinate
Solantin
Solantoin
Solantyl
Spectrum2_001281
Spectrum3_000890
Spectrum4_000984
Spectrum5_001369
Spectrum_001105
Sylantoic
TOIN
Tacosal
Thilophenyl
Toin unicelles
UNII-6158TKW0C5
WLN: T5MVMV EHJ ER& ER
ZINC02510358
ZINC18140189
Zentronal
Zentropil
component of Mebroin
elepsi ndon
epasmir ''5''
fen toin
fenidantoin ''s''
ictalis simp le
phenat ine
phenytoin
phenytoin (PHN)
taco sal
11
Folic Acidapproved, nutraceutical, vet_approvedPhase 3427959-30-36037
Synonyms:
(2S)-2-[[4-[(2-amino-4-oxo-1H-pteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid
01769_FLUKA
2d0k
33609-88-0
36653-55-1 (mono-potassium salt)
59-30-3
6484-89-5 (mono-hydrochloride salt)
AC-11682
AC1L1LNX
AI3-26387
AKOS000503224
ARONIS014410
Acfol (Spain)
Acide folique
Acide folique [INN-French]
Acido folico
Acido folico [INN-Spanish]
Acidum folicum
Acidum folicum [INN-Latin]
Acifolic
Antianemia factor
Apo-Folic
BIDD:ER0563
BIDD:GT0641
BIF0608
BPBio1_000654
BSPBio_000594
BSPBio_002338
C00504
C20H20N6O6
CAS-59-30-3
CCRIS 666
CHEBI:27470
CHEMBL1622
CID6037
CPD000471860
Cytofol
D00070
DB00158
DivK1c_000494
Dosfolat B activ
EINECS 200-419-0
F0043
F7876_SIAL
F7876_SIGMA
F8758_SIGMA
F8798_SIAL
F8890_SIGMA
FOL
Facid
Factor U
Folacid
Folacin
Folaemin
Folaemin [Netherlands]
Folan
Folasic (Australia)
Folate
Folbal
Folcidin
Folcidin (VAN)
Folcysteine
Foldine
Foldine [France]
Folettes
Foliamin
Folic
Folic acid
Folic acid (JP15/USP/INN)
Folic acid (TN)
Folic acid [BAN:INN:JAN]
Folic acid [INN:BAN:JAN]
Folic acid dihydrate
Folicet
Folicet (TN)
Folico
Folico (Italy)
Folina
Folina (Italy)
Folipac
Folsaeure
 
Folsan
Folsaure
Folsav
Folvite
Folvron
Glutamic acid, N-(p-(((2-amino-4-hydroxypyrimido(4,5-b)pyrazin-6-yl)methyl)amino)benzoyl)-, L
HMS1921D20
HMS2092N17
HMS501I16
HSDB 2002
IDI1_000494
InChI=1/C19H19N7O6/c20-19-25-15-14(17(30)26-19)23-11(8-22-15)7-21-10-3-1-9(2-4-10)16(29)24-12(18(31)32)5-6-13(27)28/h1-4,8,12,21H,5-7H2,(H,24,29)(H,27,28)(H,31,32)(H3,20,22,25,26,30)/t12-/m0/s
Incafolic
KBio1_000494
KBio2_001861
KBio2_004429
KBio2_006997
KBio3_001558
KBioGR_002222
KBioSS_001861
Kyselina listova
Kyselina listova [Czech]
LS-2157
Liver Lactobacillus casei factor
MLS001304016
MLS001335861
Millafol
Mission prenatal
Mittafol
MolPort-004-285-551
N-(4-(((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzo- yl)-L-glutamic acid
N-(4-((2-Amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-(4-{[(2-Amino-4-oxo-3,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}benzoyl)-L-glutamic acid
N-(p-(((2-Amino-4-hydroxy-6-pteridinyl)methyl)amino)benzoyl)-L-glutamic acid
N-Pteroyl-L-glutamic acid
N-[(4-{[(2-Amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[(4-{[(2-amino-4-oxo-1,4-dihydropteridin-6-yl)methyl]amino}phenyl)carbonyl]-L-glutamic acid
N-[4-[[(2-Amino-3,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-L-glutamic acid
NCGC00016265-01
NCGC00142391-01
NINDS_000494
NSC 3073
Nifolin
Nifolin [Denmark]
Novofolacid
Novofolacid [Canada]
PGA
PGA (VAN)
Prestwick3_000627
Prestwick_230
PteGlu
Pteroyl-L-glutamate
Pteroyl-L-glutamic acid
Pteroyl-L-monoglutamate
Pteroyl-L-monoglutamic acid
Pteroylglutamate
Pteroylglutamic acid
Pteroylmonoglutamate
Pteroylmonoglutamic acid
SAM002264616
SDCCGMLS-0066738.P001
SMP2_000137
SMR000471860
SPBio_001357
SPECTRUM1502020
Serum Folate Level
Spectrum2_001459
Spectrum3_000749
Spectrum4_001751
Spectrum5_000602
Spectrum_001381
UNII-935E97BOY8
Usaf cb-13
Vitamin B11
Vitamin B9
Vitamin Bc
Vitamin Be
Vitamin M
bmse000299
folic acid
nchembio.108-comp10
12Sodium Channel BlockersPhase 31515
13Vitamin B ComplexPhase 34229
14VitaminsPhase 35095
15Trace ElementsPhase 35802
16HematinicsPhase 31630
17MicronutrientsPhase 35802
18AnticonvulsantsPhase 32620
19Diuretics, Potassium SparingPhase 31827
20Folinic AcidNutraceuticalPhase 33150
21FolateNutraceuticalPhase 34279
22Vitamin B9NutraceuticalPhase 34279
23
Chlorhexidineapproved, vet_approvedPhase 247255-56-19552079, 2713
Synonyms:
1,1 inverted exclamation marka-Hexamethylenebis[5-(4-chlorophenyl)biguanide]
1,1'-Hexamethylene bis(5-(P-chlorophenyl)biguanide)
1,1'-Hexamethylene bis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis(5-(p-chlorophenyl)biguanide)
1,1'-Hexamethylenebis[5-(4-chlorophenyl)biguanide
1,6-Bis(5-(p-chlorophenyl)biguandino)hexane
1,6-Bis(p-chlorophenyldiguanido)hexane
1,6-Di(4'-chlorophenyldiguanido)hexane
1,6-Di(N-p-chlorophenyldiguanido)hexane
24798_FLUKA
282227_ALDRICH
348031_ALDRICH
4-12-00-01201 (Beilstein Handbook Reference)
55-56-1
AB00053427
AB1003159
AVAGARD
BPBio1_000272
BRN 2826432
BSPBio_000246
BSPBio_001977
C06902
C22H30Cl2N10
CAS-55-56-1
CCRIS 9230
CHEBI:3614
CHEMBL790
CID9552079
Chlorhexidin
Chlorhexidin [Czech]
Chlorhexidine
Chlorhexidine (INN)
Chlorhexidine Base
Chlorhexidine [INN:BAN]
Chlorhexidine gluconate
Chlorhexidinum
Chlorhexidinum [INN-Latin]
Cloresidina
Cloresidina [DCIT]
Clorhexidina
Clorhexidina [INN-Spanish]
D07668
DB00878
Decanoylacetaldehyde Sodium Sulfide
Dentisept [veterinary]
Dentisept [veterinary] (TN)
DivK1c_000761
EINECS 200-238-7
Fimeil
HMS1568M08
HSDB 7196
Hexadol
Hibiclens
Hibispray
Hibistat
I06-0621
I14-0050
IDI1_000761
 
KBio1_000761
KBio2_000717
KBio2_003285
KBio2_005853
KBio3_001197
KBioGR_000774
KBioSS_000717
LS-43917
Lisium (*Dihydrochloride*)
MK-412A
MLS001332387
MLS001332388
MLS002154209
Merfen-incolore
Merfen-incolore (TN)
MolPort-002-541-741
N',N'''''-hexane-1,6-diylbis[N-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N''''-hexane-1,6-diylbis[N'-(4-chlorophenyl)(imidodicarbonimidic diamide)]
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradeca- nediimidamide
N,N'-Bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
N,N'-bis(4-chlorophenyl)-3,12-diimino-2,4,11,13-tetraazatetradecanediimidamide
NCGC00016246-01
NCGC00091025-01
NCGC00091025-02
NINDS_000761
NSC526936
Nolvasan
Nolvasan (*Diacetate*)
Novalsan
Oro-Clense
Peridex
Periogard
Prestwick0_000143
Prestwick1_000143
Prestwick2_000143
Prestwick3_000143
Prestwick_53
QTL1_000020
Rotersept
SMR000857146
SPBio_000210
SPBio_002185
STK089248
STOCK1S-18831
Savloclens
Savlon babycare
Sebidin A
Sodium Houttuyfonamide
Soretol
Spectrum2_000135
Spectrum3_000339
Spectrum4_000277
Spectrum5_001322
Spectrum_000237
Sterido
Sterilon
Superspray
Tubulicid
UNII-R4KO0DY52L
chlorhexidine
24DisinfectantsPhase 2547
25Anti-Infective Agents, LocalPhase 21785
26Chlorhexidine gluconatePhase 2472
27
Salicylic acidapproved, vet_approved17569-72-7338
Synonyms:
105910_ALDRICH
105910_SIAL
2 Hydroxybenzoic Acid
2-Carboxyphenol
2-Hydroxybenzenecarboxylate
2-Hydroxybenzenecarboxylic acid
2-Hydroxybenzoate
2-Hydroxybenzoic acid
2-hydroxy(1-14c)benzoic acid
247588_SIAL
27301_SIAL
69-72-7
7681-06-3
8052-31-1
84210_FLUKA
84210_SIAL
AB1002436
AC1L190M
AC1Q1HCK
AC1Q72IF
AI3-02407
AKOS000118979
ALPHA/BETA HYDROXY ACIDS (SALICYLIC ACID) (SEE ALPHA/BETA HYDROXY ACIDS)
AR-1E2203
ATA fraction 10, ammonium salt
Acid, 2-Hydroxybenzoic
Acid, Salicylic
Acid, o-Hydroxybenzoic
Acid, ortho-Hydroxybenzoic
Acido o-idrossibenzoico
Acido o-idrossibenzoico [Italian]
Acido salicilico
Acido salicilico [Italian]
Acidum salicylicum
Advanced Pain Relief Callus Removers
Advanced Pain Relief Corn Removers
Advanced pain relief callus removers
Advanced pain relief corn removers
Akurza Cream
Akurza Lotion
Alpha/Beta Hydroxy Acids (Glycolic Acid, Salicylic Acid)
BENZOIC ACID,2-HYDROXY SALICYLIC ACID
BIDD:ER0602
BRN 0774890
Benzoic acid, 2-hydroxy- (9CI)
C00805
CCRIS 6714
CHEBI:16914
CHEMBL424
CID338
CMC_13852
Caswell No. 731
Clear away Wart Remover
Clear away wart remover
Compound W
Compound w
D00097
D020156
DB00936
DHS Sal Shampoo
DivK1c_000301
Domerine
Dr. Scholl'S Callus Removers
Dr. Scholl'S Corn Removers
Dr. Scholl'S Wart Remover Kit
Dr. Scholl's callus removers
Dr. Scholl's corn removers
Dr. Scholl's wart remover kit
DuoPlant Gel
Duofil Wart Remover
Duofil wart remover
Duofilm
Duoplant
E9A559BE-383B-4F83-BC02-3031D03D558A
EINECS 200-712-3
EPA Pesticide Chemical Code 076602
Freezone
H0206
HSDB 672
Hydrisalic Gel
I04-0192
IDI1_000301
InChI=1/C7H6O3/c8-6-4-2-1-3-5(6)7(9)10/h1-4,8H,(H,9,10
Ionil
Ionil Plus
Ionil plus
Ionil-Plus
 
K 537
K 557
KBio1_000301
KBio2_001428
KBio2_003996
KBio2_006564
KBioSS_001428
Keralyt
Kyselina 2-hydroxybenzoova
Kyselina 2-hydroxybenzoova [Czech]
Kyselina salicylova
Kyselina salicylova [Czech]
LS-2169
MLS000069653
Mediplast pads
MolPort-001-769-476
NCGC00159447-02
NCGC00159447-04
NINDS_000301
NSC 180
NSC180
NSC629474
O-Carboxyphenol
O-Hydroxybenzoate
O-Hydroxybenzoic acid
O-carboxyphenol
O-hydroxybenzoic acid
Occlusal
Oprea1_040343
Orthohydroxybenzoic acid
P&S Shampoo
Phenol-2-carboxylate
Phenol-2-carboxylic acid
Propa pH Peel-Off Acne Mask
Psoriacid-S-Stift
Psoriacid-S-stift
Retarder SAX
Retarder W
Rutranex
S5922_SIGMA
S7401_SIGMA
S8519_SIGMA
SALICYLIC ACID (SEE ALSO ALPHA HYDROXY ACIDS)
SALICYLIC ACID, ACS
SAX
SBB052826
SGCUT00012
SMP2_000145
SMR000059163
STK258681
Salex Cream
Salex Lotion
Salicyclic acid
Salicylate
Salicylic acid
Salicylic acid & Sulfur Soap
Salicylic acid (6CI,8CI)
Salicylic acid (JP15/USP)
Salicylic acid (TN)
Salicylic acid Soap
Salicylic acid [USAN:JAN]
Salicylic acid collodion
Salicylic acid soap
Salicylic acid, tech
Salicylic acid, tech.
Salicylic acid-ring-UL-14C
Saligel
Salonil
Sebucare
Sebulex
Spectrum_000948
Stri-Dex
Trans-Ver-Sal
UNII-O414PZ4LPZ
UPCMLD-DP126
UPCMLD-DP126:001
Verrugon
W398500_ALDRICH
WLN: QVR BQ
bmse000252
o Hydroxybenzoic Acid
o-Carboxyphenol
o-hydroxybenzoic acid
ortho Hydroxybenzoic Acid
ortho-Hydroxybenzoic Acid
phenol derivative, 7
salicylate
salicylic acid
to_000004
28calcium channel blockers1940
29Calcium, Dietary5525

Interventional clinical trials:

idNameStatusNCT IDPhase
1Efficacy and Safety Study of the Switch From Cyclosporin to Tacrolimus in Renal Transplant RecipientsCompletedNCT02706678Phase 4
2Folic Acid Supplementation in Phenytoin Induced Gingival OvergrowthCompletedNCT00781196Phase 3
3Effect of Supragingival Irrigators Containing Chlorhexidine on Oral Health in Blood DyscrasiaCompletedNCT01974401Phase 2
4Diode Laser in Gingival Enlargement Related to OrthodonticsUnknown statusNCT01286298
5Genes Associated With Hereditary and Drug-Induced Gingival OvergrowthCompletedNCT00104026
6Flapless Esthetic Crown Lengthening for the Treatment of Excessive Gingival DisplayCompletedNCT01821157
7Study of Immunosuppressive Therapy Toxicities in Kidney Transplant Recipients at Regional or Satellite Community ClinicsCompletedNCT00902980
8Salivary Inflammatory Biomarkers: Predictors & Comparative Effects of Sonicare/Elite-Flexcare in Stages of Perio DiseaseCompletedNCT02187185
9IL29 and IL28B Variants Associated With Periodontal Disease PathogenesisRecruitingNCT02710903

Search NIH Clinical Center for Gingival Overgrowth


Cochrane evidence based reviews: gingival overgrowth

Genetic Tests for Gingival Overgrowth

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Genetic tests related to Gingival Overgrowth:

id Genetic test Affiliating Genes
1 Gingival Overgrowth26

Anatomical Context for Gingival Overgrowth

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MalaCards organs/tissues related to Gingival Overgrowth:

35
Heart, Kidney, Liver, Endothelial, Lung, Bone, Bone marrow

Animal Models for Gingival Overgrowth or affiliated genes

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MGI Mouse Phenotypes related to Gingival Overgrowth:

40 (show all 12)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053818.9CD36, CTGF, CTSB, DCN, IL6, TGFB1
2MP:00053888.4CTGF, DCN, FAM20A, IL6, PDGFB, TGFB1
3MP:00053678.2CD36, CTSB, DCN, FAM20A, IL6, PDGFB
4MP:00020068.1CTSB, DCN, IL1A, IL6, MMP1, TGFB1
5MP:00107718.1CTGF, CTSB, DCN, IL1A, IL6, PDGFB
6MP:00053907.9CD36, CTGF, DCN, FAM20A, IL6, MMP3
7MP:00053857.9CD36, CTGF, FAM20A, IL1A, IL6, PDGFB
8MP:00053977.8CD36, DCN, IL1A, IL6, MMP3, PDGFB
9MP:00053787.7CD36, CTGF, CTSB, DCN, FAM20A, IL6
10MP:00053917.6CD36, CTGF, DCN, FAM20A, IL6, PDGFB
11MP:00053877.1CD36, CTSB, DCN, IL1A, IL6, MMP1
12MP:00053766.8CD36, CTGF, CTSB, DCN, IL1A, IL6

Publications for Gingival Overgrowth

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Articles related to Gingival Overgrowth:

(show top 50)    (show all 441)
idTitleAuthorsYear
1
A Clinical Evaluation of Gingival Overgrowth in Children on Antiepileptic Drug Therapy. (26894172)
2016
2
Amlodipine-Induced Gingival Overgrowth. (27731568)
2016
3
Gingival overgrowth as secondary effect of calcium channel blockers administration. A case report. (25408733)
2014
4
Can chlorhexidine mouthwash twice daily ameliorate cyclosporine-induced gingival overgrowth? (23473525)
2013
5
Molecular events associated with ciclosporin A-induced gingival overgrowth are attenuated by Smad7 overexpression in fibroblasts. (21883230)
2012
6
Loss of basement membrane integrity in human gingival overgrowth. (21483030)
2011
7
Surgical management of gingival overgrowth associated with Cowden sydrome: a case report and current understanding. (21519553)
2011
8
Reduction in lipopolysaccharide-induced apoptosis of fibroblasts obtained from a patient with gingival overgrowth during nifedipine-treatment. (21474118)
2011
9
Down-regulation of transforming growth factor beta-2 expression is associated with the reduction of cyclosporin induced gingival overgrowth in rats treated with roxithromycin: an experimental study. (19995419)
2009
10
Gingival overgrowth, congenital generalized hypertrichosis, mental retardation and epilepsy: case report and overview. (19625955)
2009
11
Gingival overgrowth in a renal transplant recipient using cyclosporine A. (19040821)
2008
12
Expression of fibronectin-binding integrins in gingival epithelium in drug-induced gingival overgrowth. (17305873)
2007
13
Apoptosis and expression of caspase-3 in cyclosporin-induced gingival overgrowth. (18052710)
2007
14
The role of nickel accumulation and epithelial cell proliferation in orthodontic treatment-induced gingival overgrowth. (17989122)
2007
15
Incidence of tacrolimus-induced gingival overgrowth in the absence of calcium channel blockers: a short-term study. (17433046)
2007
16
Elevated levels of gene expression for collagen and decorin in human gingival overgrowth. (16820039)
2006
17
The relationship between proliferating cell nuclear antigen expression and histomorphometrical alterations in cyclosporin A-induced gingival overgrowth in rats. (16546941)
2006
18
Apoptosis in cyclosporin A-induced gingival overgrowth: a histological study. (15974838)
2005
19
Gingival tissue proteoglycan and chondroitin-4-sulphate levels in cyclosporin A-induced gingival overgrowth and the effects of initial periodontal treatment. (15882223)
2005
20
CYP2C polymorphisms, phenytoin metabolism and gingival overgrowth in epileptic subjects. (14659971)
2004
21
Antibiotic treatment of incipient drug-induced gingival overgrowth in adult renal transplant patients. (12608908)
2003
22
Immunohistochemical analysis of Th1/Th2 cytokine profiles and androgen receptor expression in the pathogenesis of nifedipine-induced gingival overgrowth. (12828661)
2003
23
Cytomegalovirus and cyclosporin-induced gingival overgrowth in children with liver grafts. (12121533)
2002
24
Plasma cell granuloma in cyclosporine-induced gingival overgrowth: a report of two cases with immunohistochemical positivity of interleukin-6 and phospholipase C-gamma1. (12378028)
2002
25
Investigation of the effect of FK506 (tacrolimus) and cyclosporin on gingival overgrowth following paediatric liver transplantation. (12452980)
2002
26
Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice. (12466121)
2002
27
Calcium channel blocker induced gingival overgrowth. (12147940)
2002
28
Cyclosporin A upregulates phospholipase C beta1 in fibroblasts from gingival overgrowth. (11128920)
2000
29
Effectiveness of periodontal therapy in patients with drug-induced gingival overgrowth. Long-term results. (10505798)
1999
30
Contribution of individual drugs to gingival overgrowth in adult and juvenile renal transplant patients treated with multiple therapy. (9667479)
1998
31
Increased bFGF level in the serum of patients with phenytoin-induced gingival overgrowth. (9477019)
1998
32
Role of medullasin in nifedipine-induced gingival overgrowth in rats. (9796781)
1998
33
Phenytoin-induced gingival overgrowth: a community-based cross-sectional study in Ferrara, Italy. (9430129)
1997
34
Human papillomavirus in a patient with severe gingival overgrowth associated with cyclosporine therapy. A case report. (8724712)
1996
35
Nifedipine-associated gingival overgrowth: a survey of the literature and report of four cases. (9063228)
1996
36
Determinants of gingival overgrowth severity in organ transplant patients. An examination of the rA'le of HLA phenotype. (8841894)
1996
37
Gingival overgrowth in paediatric cardiac transplant patients: a study of 19 patients aged between 2 and 16 years. (8957834)
1995
38
The pharmacokinetics of phenytoin in gingival crevicular fluid and plasma in relation to gingival overgrowth. (8613563)
1995
39
Altered collagen metabolism in nifedipine-induced gingival overgrowth. (7877076)
1994
40
Immunohistochemical study of 30 cases of cyclosporin A-induced gingival overgrowth. (7608852)
1994
41
Effect of periodontal treatment on gingival overgrowth among cyclosporine A-treated renal transplant recipients. (8295099)
1993
42
Gingival overgrowth among renal transplant recipients and uraemic patients. (8302465)
1993
43
Nifedipine-induced gingival overgrowth in the presence or absence of gingival inflammation in rats. (8254456)
1993
44
Incidence and severity of phenytoin-induced gingival overgrowth in epileptic patients in general medical practice. (1424550)
1992
45
Phenytoin-induced gingival overgrowth in rats infected with Streptococcus sobrinus 6715. (2151111)
1990
46
The reduction of phenytoin-induced gingival overgrowth in a severely disabled patient: a case report. (2605605)
1989
47
Cyclosporine-induced gingival overgrowth: an ultrastructural stereologic study. (3422723)
1988
48
Cyclosporin-induced gingival overgrowth: correlation with dental plaque scores, gingivitis scores, and cyclosporin levels in serum and saliva. (3477745)
1987
49
Cyclosporine and gingival overgrowth. (3123625)
1987
50
Quantitative histopathologic assessment of developing phenytoin-induced gingival overgrowth in the cat. (6958684)
1982

Variations for Gingival Overgrowth

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Copy number variations for Gingival Overgrowth from CNVD:

6
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1116297176420000070900000Copy numberGingival hyperplasia

Expression for genes affiliated with Gingival Overgrowth

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Search GEO for disease gene expression data for Gingival Overgrowth.

Pathways for genes affiliated with Gingival Overgrowth

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Pathways related to Gingival Overgrowth according to GeneCards Suite gene sharing:

(show all 31)
idSuper pathwaysScoreTop Affiliating Genes
110.0MMP1, TGFB1
29.9MMP1, TIMP1
39.7IL6, TGFB1
4
Show member pathways
9.5MMP1, MMP3, TIMP1
59.5MMP1, MMP3, TIMP1
6
Show member pathways
9.5MMP1, MMP3, TIMP1
7
Show member pathways
9.5MMP3, TGFB1, TIMP1
89.4IL6, MMP1, TGFB1
99.4IL6, PDGFB, TGFB1
109.3CD36, IL6, TGFB1
119.3CD36, IL6, TGFB1
129.2DCN, IL6, MMP1
13
Show member pathways
9.1CTSB, CTSL, IL6
149.1IL6, MMP1, PDGFB, TGFB1
158.9IL1A, IL6, TGFB1
168.9IL1A, IL6, TGFB1
178.9IL1A, IL6, TGFB1
188.9IL1A, IL6, TGFB1
198.8DCN, IL6, PDGFB, TGFB1
208.8CD36, IL1A, IL6
21
Show member pathways
8.8CTGF, IL6, PDGFB, TGFB1, TIMP1
22
Show member pathways
8.8CTGF, IL6, PDGFB, TGFB1, TIMP1
238.8CTGF, IL6, PDGFB, TGFB1, TIMP1
24
Show member pathways
8.0CTSB, CTSL, IL1A, IL6, TGFB1
25
Show member pathways
8.0CTGF, IL1A, IL6, PDGFB, TGFB1, TIMP1
26
Show member pathways
8.0CTGF, IL1A, IL6, PDGFB, TGFB1, TIMP1
27
Show member pathways
8.0CTGF, IL1A, IL6, PDGFB, TGFB1, TIMP1
28
Show member pathways
8.0CTGF, IL1A, IL6, PDGFB, TGFB1, TIMP1
29
Show member pathways
8.0CTGF, IL1A, IL6, PDGFB, TGFB1, TIMP1
307.8CTSL, IL1A, IL6, MMP1, MMP3, TGFB1
31
Show member pathways
7.6CTSB, CTSL, DCN, MMP1, MMP3, PDGFB

GO Terms for genes affiliated with Gingival Overgrowth

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Cellular components related to Gingival Overgrowth according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1platelet alpha granule lumenGO:003109310.2PDGFB, TGFB1, TIMP1
2endolysosome lumenGO:003602110.1CTSB, CTSL
3extracellular matrixGO:00310129.2DCN, PDGFB, TGFB1, TIMP1
4proteinaceous extracellular matrixGO:00055788.6CTGF, DCN, MMP1, MMP3, TGFB1, TIMP1
5extracellular spaceGO:00056155.9CD36, CTGF, CTSB, CTSL, DCN, IL1A
6extracellular regionGO:00055765.6CTGF, CTSB, CTSL, DCN, IL1A, IL6

Biological processes related to Gingival Overgrowth according to GeneCards Suite gene sharing:

(show all 32)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of blood vessel endothelial cell migrationGO:004353610.5PDGFB, TGFB1
2positive regulation of pri-miRNA transcription from RNA polymerase II promoterGO:190289510.5PDGFB, TGFB1
3positive regulation of chemotaxisGO:005092110.5PDGFB, TGFB1
4positive regulation of collagen biosynthetic processGO:003296710.5CTGF, TGFB1
5cell activationGO:000177510.5TGFB1, TIMP1
6positive regulation of protein oligomerizationGO:003246110.4MMP1, MMP3
7response to fatty acidGO:007054210.4CD36, CTGF
8cellular response to thyroid hormone stimulusGO:009706710.1CTSB, CTSL
9connective tissue replacement involved in inflammatory response wound healingGO:000224810.1IL1A, TGFB1
10response to glucoseGO:000974910.0CTGF, CTSB, TGFB1
11response to peptide hormoneGO:00434349.9CTGF, CTSB, TIMP1
12positive regulation of protein phosphorylationGO:00019349.8CTGF, FAM20A, TGFB1
13platelet degranulationGO:00025769.8CD36, PDGFB, TGFB1, TIMP1
14response to estradiolGO:00323559.8CTGF, PDGFB, TGFB1
15positive regulation of vascular endothelial growth factor productionGO:00105759.7IL1A, TGFB1
16cell growthGO:00160499.7IL6, PDGFB, TGFB1
17positive regulation of cell divisionGO:00517819.6IL1A, PDGFB, TGFB1
18positive regulation of MAPK cascadeGO:00434109.6CD36, IL6, PDGFB
19negative regulation of gene expressionGO:00106299.6CD36, CTGF, PDGFB, TGFB1
20positive regulation of peptidyl-tyrosine phosphorylationGO:00507319.4CD36, IL6, PDGFB, TGFB1
21collagen catabolic processGO:00305749.4CTSB, CTSL, MMP1, MMP3
22response to organic cyclic compoundGO:00140709.3CTGF, CTSB, IL6, TGFB1
23positive regulation of interleukin-6 productionGO:00327559.2CD36, IL1A, IL6
24cytokine-mediated signaling pathwayGO:00192219.1DCN, IL1A, IL6
25extracellular matrix disassemblyGO:00226179.1CTSL, DCN, MMP1, MMP3, TIMP1
26response to woundingGO:00096119.1CTGF, CTSB, IL6, PDGFB, TGFB1
27positive regulation of mitotic nuclear divisionGO:00458409.0IL1A, PDGFB
28positive regulation of ERK1 and ERK2 cascadeGO:00703748.9CD36, CTGF, IL6, PDGFB
29wound healingGO:00420608.8DCN, IL6, PDGFB, TGFB1, TIMP1
30positive regulation of cell proliferationGO:00082848.8CTGF, IL6, PDGFB, TGFB1, TIMP1
31agingGO:00075688.8CTGF, DCN, IL6, TGFB1, TIMP1
32positive regulation of gene expressionGO:00106288.3CTGF, IL1A, IL6, PDGFB, TGFB1

Molecular functions related to Gingival Overgrowth according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1protein serine/threonine kinase activator activityGO:004353910.1FAM20A, TGFB1
2proteoglycan bindingGO:00433949.8CTSB, CTSL
3serine-type endopeptidase activityGO:00042529.0CTSB, CTSL, MMP1, MMP3
4cytokine activityGO:00051258.8IL1A, IL6, TGFB1, TIMP1
5collagen bindingGO:00055188.8CTSB, CTSL, DCN, PDGFB
6growth factor activityGO:00080838.5CTGF, IL6, PDGFB, TGFB1, TIMP1

Sources for Gingival Overgrowth

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2CDC
6CNVD
10DGIdb
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16FDA
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26GTR
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