MCID: GNG003
MIFTS: 40

Gingival Recession malady

Gastrointestinal diseases category

Summaries for Gingival Recession

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63Wikipedia, 32MalaCards
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Wikipedia:63 In dentistry, gingival recession (receding gums) is the exposure in the roots of the teeth caused by a... more...

MalaCards: Gingival Recession, also known as localized gingival recession, is related to gingivitis and periodontitis. An important gene associated with Gingival Recession is DSPP (dentin sialophosphoprotein). The compounds benzalkonium chloride and minocycline have been mentioned in the context of this disorder. Affiliated tissues include bone, tongue and testes.

Aliases & Classifications for Gingival Recession

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 30LifeMap Discovery™, 60UMLS, 27ICD9CM, 56SNOMED-CT, 34MeSH, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

gingival recession 8 10 44 30 60
localized gingival recession 8 60
gingival recession, unspecified 8
gingival recession, localized 8
gingival recession, minimal 60
moderate gingival recession 8
minimal gingival recession 8
gingival recession, severe 60
severe gingival recession 8
gingival recession nos 8


External Ids:

Disease Ontology8 DOID:1134
ICD9CM27 523.2, 523.20
MeSH34 D005889
NCIt39 C82068
ICD1025 K06.0

Related Diseases for Gingival Recession

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Gingival Recession via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 19)
idRelated DiseaseScoreTop Affiliating Genes
1gingivitis31.8DSPP, IL1A
2periodontitis30.9IL1A
3periodontal disease30.1IL1A, DSPP
4cervicitis10.4
5cleft lip10.2
6cleft palate10.2
7conjunctivitis10.2
8gingival disease10.2
9periostitis10.2
10endometritis10.0DSPP
11dermatomyositis10.0IL1A
12pulpitis10.0IL1A, DSPP
13gingival overgrowth10.0IL1A, DSPP
14graft versus host disease9.9
15root resorption9.9
16localized scleroderma9.9
17scleroderma9.9
18colorectal cancer9.9
19ehlers-danlos syndrome, periodontitis type9.9

Graphical network of diseases related to Gingival Recession:



Diseases related to gingival recession

Clinical Features for Gingival Recession

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Drugs & Therapeutics for Gingival Recession

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 30LifeMap Discovery™, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Gingival Recession

Search CenterWatch for Gingival Recession

Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Gingival Recession cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Gingival Recession:
Adipose-derived vascular fraction cells for gingival gum regeneration
GINTUIT
Embryonic/Adult Cultured Cells Related to Gingival Recession:
Bilayered cell therapy, PMIDs: 22678374, 18834238
GLP-transfected mesenchymal stem cells, PMIDs: 22985173, 22034462

Genetic Tests for Gingival Recession

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Anatomical Context for Gingival Recession

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32MalaCards
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MalaCards organs/tissues related to Gingival Recession:

32
Bone, Tongue, Testes

Animal Models for Gingival Recession or affiliated genes

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Publications for Gingival Recession

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50PubMed
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Articles related to Gingival Recession:

(show top 50)    (show all 365)
idTitleAuthorsYear
1
Prevalence and associated factors of gingival recession in Greek adults. (23447386)
2013
2
Unexpected resilience to experimental gingivitis of subepithelial connective tissue grafts in gingival recession defects: a clinical-molecular evaluation. (24117898)
2013
3
Coverage of gingival recession defects using acellular dermal matrix allograft with or without beta-tricalcium phosphate. (21862508)
2013
4
Comparative evaluation of the effectiveness of coronally positioned flap with or without acellular dermal matrix allograft in the treatment of multiple marginal gingival recession defects. (23593633)
2013
5
Surgical treatment options for grafting areas of gingival recession association with cervical lesions: a review. (24103046)
2013
6
Efficacy of acellular dermal matrix and coronally advanced flaps for the treatment of induced gingival recession defects: a histomorphometric study in dogs. (23088530)
2013
7
Combined orthodontic - mucogingival treatment of a deep post-orthodontic gingival recession. (22908075)
2012
8
Clinical evaluation of GEM 21S(Ar) and a collagen membrane with a coronally advanced flap as a root coverage procedure in the treatment of gingival recession defects: A comparative study. (23493720)
2012
9
Gingival recession in individuals with cleft lip and palate: prevalence and severity. (21534842)
2012
10
Gingival recession: part 3. Surgical management using free grafts and guided tissue regeneration. (22015511)
2011
11
Periodontal plastic surgery procedures reduce localized gingival recession defects. (21719809)
2011
12
Is gingival recession a consequence of an orthodontic tooth size and/or tooth position discrepancy? "A paradigm shift". (21462624)
2011
13
Coronally positioned flap with or without acellular dermal matrix graft in the treatment of class II gingival recession defects: A randomized controlled clinical study. (22114387)
2010
14
Letter to the editor: re: "treatment of multiple areas of gingival recession using a simple harvesting technique for autogenous connective tissue graft". (20225939)
2010
15
The influence of local anatomy on the outcome of treatment of gingival recession associated with non-carious cervical lesions. (20214443)
2010
16
Effects of the combined desensitizing dentifrice and diode laser therapy in the treatment of desensitization of teeth with gingival recession. (20863237)
2010
17
Root surface biomodification with an Er:YAG laser for the treatment of gingival recession with subepithelial connective tissue grafts. (19780631)
2010
18
The coronally advanced flap in combination with platelet-rich fibrin (PRF) and enamel matrix derivative in the treatment of gingival recession: a comparative study. (20820456)
2010
19
Risk assessment for buccal gingival recession defects in an adult population. (20476890)
2010
20
Clinical showcase. Treatment of gingival recession with subepithelial connective tissue harvested from the maxillary tuberosity by distal wedge procedure. (19900352)
2009
21
Connective tissue graft plus resin-modified glass ionomer restoration for the treatment of gingival recession associated with non-carious cervical lesion: a randomized-controlled clinical trial. (19594663)
2009
22
No good evidence to link toothbrushing trauma to gingival recession. (18584004)
2008
23
An alternative treatment approach to gingival recession: gingiva-colored partial porcelain veneers: a clinical report. (17692588)
2007
24
Comparative 6-month clinical study of a semilunar coronally positioned flap and subepithelial connective tissue graft for the treatment of gingival recession. (16460241)
2006
25
Treatment of gingival recession using a collagen membrane with or without the use of demineralized freeze-dried bone allograft for space maintenance. (15068108)
2004
26
Root coverage of advanced gingival recession: a comparative study between acellular dermal matrix allograft and subepithelial connective tissue grafts. (12546089)
2002
27
A 3-year longitudinal evaluation of subpedicle free connective tissue graft for gingival recession coverage. (12546090)
2002
28
Gingival recession and toothbrushing in an Italian School of Dentistry: a pilot study. (10355616)
1999
29
A team approach to hypersensitive dentine and gingival recession. (8613591)
1995
30
Gingival recession: intra-oral distribution and associated factors. (7990024)
1994
31
The prevalence and distribution of gingival recession in subjects with a high standard of oral hygiene. (8126246)
1994
32
Orthodontic treatment and isolated gingival recession: a review. (7857905)
1994
33
The subepithelial connective tissue graft for treatment of gingival recession. (8477867)
1993
34
Guided tissue regeneration procedure in the treatment of a bone dehiscence associated with a gingival recession: a case report. (1813447)
1991
35
The effect of an anticalculus dentifrice on calculus formation and gingival recession in Thai children and teenagers: one-year study. Study #1. An anticalculus dentifrice containing 3.3% soluble pyrophosphate and 1.0% of a copolymer. (1667473)
1991
36
Treatment of localised gingival recession with subpedicle connective tissue graft and free gingival auto graft--a comparative clinical evaluation. (2130101)
1990
37
Gingival recession and fenestration in orthodontic treatment. (2084153)
1990
38
Thick gingival autograft for the coverage of gingival recession: a clinical evaluation. (2098351)
1990
39
Gingival recession and plaque control. (3471334)
1987
40
Gingival recession. (6368625)
1984
41
Treatment of advanced periodontitis, severe gingival recession, and crowding of teeth in the lower anterior region of the mouth. (6587121)
1983
42
Combination of a connective tissue pedicle flap with a free gingival graft to cover localized gingival recession. (6963578)
1982
43
Combined use of the lateral sliding flap and free gingival graft procedures in treatment of gingival recession. (6964731)
1982
44
The etiology of gingival recession. Review of literature. (392016)
1979
45
Recognition and treatment of gingival recession. (4523245)
1974
46
Gingivitis and gingival recession in adults from high-fluoride and low-fluoride areas. (4506980)
1972
47
The etiology of gingival recession. (5278610)
1971
48
Gingival recession of mandibular incisors related to malocclusions of the teeth. (5287622)
1971
49
Prevalence and etiology of gingival recession. (5230025)
1967
50
Traumatic gingival recession. (5214377)
1965

Genetic Variations for Gingival Recession

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Expression for genes affiliated with Gingival Recession

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gingival Recession

Search GEO for disease gene expression data for Gingival Recession.

Pathways for genes affiliated with Gingival Recession

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Compounds for genes affiliated with Gingival Recession

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Sources:
44Novoseek, 11DrugBank, 59Tocris Bioscience, 24HMDB
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Compounds related to Gingival Recession according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1benzalkonium chloride449.7IL1A, DSPP
2minocycline44 1110.6IL1A, DSPP
3ciprofloxacin44 1110.5IL1A, DSPP
4calcitriol44 59 11 2412.5IL1A, DSPP
5tetracycline44 1110.4DSPP, IL1A
6formaldehyde44 2410.2IL1A, DSPP

GO Terms for genes affiliated with Gingival Recession

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Products for genes affiliated with Gingival Recession

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gingival Recession

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet