MCID: GNG003
MIFTS: 43

Gingival Recession malady

Gastrointestinal diseases, Oral diseases categories

Summaries for Gingival Recession

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66Wikipedia, 34MalaCards
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Wikipedia:66 In dentistry, gingival recession (receding gums) is the exposure in the roots of the teeth caused by a... more...

MalaCards: Gingival Recession, also known as localized gingival recession, is related to gingivitis and periodontal disease. An important gene associated with Gingival Recession is DSPP (dentin sialophosphoprotein). The compounds benzalkonium chloride and minocycline have been mentioned in the context of this disorder. Affiliated tissues include bone, tongue and testes.

Aliases & Classifications for Gingival Recession

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Sources:
9Disease Ontology, 11DISEASES, 46Novoseek, 32LifeMap Discoveryā„¢, 63UMLS, 36MeSH, 28ICD9CM, 59SNOMED-CT, 41NCIt, 26ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases, Oral diseases


Aliases & Descriptions:

gingival recession 9 11 46 32 63
localized gingival recession 9 63
gingival recession, unspecified 9
gingival recession, localized 9
moderate gingival recession 9
gingival recession, minimal 63
minimal gingival recession 9
gingival recession, severe 63
severe gingival recession 9
gingival recession nos 9


External Ids:

Disease Ontology9 DOID:1134
MeSH36 D005889
ICD9CM28 523.20, 523.2
NCIt41 C82068
ICD1026 K06.0

Related Diseases for Gingival Recession

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Sources:
18GeneCards, 19GeneDecks
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Diseases related to Gingival Recession via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1gingivitis31.8IL1A, DSPP
2periodontal disease30.1IL1A, DSPP
3periodontitis10.7
4cervicitis10.5
5cleft lip10.2
6conjunctivitis10.2
7periostitis10.2
8pulpitis10.0DSPP, IL1A
9graft versus host disease10.0
10localized scleroderma10.0
11root resorption10.0
12colorectal cancer10.0
13scleroderma10.0
14chronic graft versus host disease10.0
15mental retardation10.0
16ehlers-danlos syndrome, periodontitis type10.0
17gingival overgrowth10.0DSPP, IL1A
18osteoarthritis10.0DSPP, IL1A

Graphical network of diseases related to Gingival Recession:



Diseases related to gingival recession

Symptoms for Gingival Recession

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Drugs & Therapeutics for Gingival Recession

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Sources:
6CenterWatch, 43NIH Clinical Center, 7ClinicalTrials, 32LifeMap Discoveryā„¢, 63UMLS, 42NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Gingival Recession

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Cell-based therapeutics:


LifeMap Discovery
The database of embryonic development, stem cell research and regenerative medicine
Read about Gingival Recession cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Gingival Recession:
Adipose-derived vascular fraction cells for gingival gum regeneration
GINTUIT
Embryonic/Adult Cultured Cells Related to Gingival Recession:
Bilayered cell therapy, PMIDs: 22678374, 18834238
GLP-transfected mesenchymal stem cells, PMIDs: 22985173, 22034462

Genetic Tests for Gingival Recession

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Anatomical Context for Gingival Recession

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34MalaCards
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MalaCards organs/tissues related to Gingival Recession:

34
Bone, Tongue, Testes

Animal Models for Gingival Recession or affiliated genes

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Publications for Gingival Recession

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53PubMed
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Articles related to Gingival Recession:

(show top 50)    (show all 363)
idTitleAuthorsYear
1
Mineral trioxide aggregate and subepithelial connective tissue graft for treatment of iatrogenic gingival recession: long-term results. (24396836)
2014
2
Prevalence and associated factors of gingival recession in Greek adults. (23447386)
2013
3
Periodontal plastic microsurgery in the treatment of deep gingival recession after orthodontic movement. (24312735)
2013
4
Use of autologous platelet rich plasma to treat gingival recession in esthetic periodontal surgery. (24049336)
2013
5
Association between gingival recession and proclination of maxillary central incisors near the cleft in patients with unilateral cleft lip and palate: A retrospective case-control study. (23452970)
2013
6
Impact of interleukin 1 gene polymorphism and smoking on long-term stability following gingival recession treatment. (23342354)
2013
7
Subepithelial connective tissue graft with growth factor for the treatment of maxillary gingival recession defects. (23342346)
2013
8
Treatment of gingival recession defects with a coronally advanced flap and a xenogeneic collagen matrix: a multicenter randomized clinical trial. (23050490)
2013
9
Unexpected resilience to experimental gingivitis of subepithelial connective tissue grafts in gingival recession defects: a clinical-molecular evaluation. (24117898)
2013
10
COMMENTARY. Conservative management of gingival recession: the gingival veneer. (23205685)
2012
11
Combined orthodontic - mucogingival treatment of a deep post-orthodontic gingival recession. (22908075)
2012
12
Response of pulp sensibility test is strongly influenced by periodontal attachment loss and gingival recession. (22515882)
2012
13
Apical surgery may cause gingival recession. (23253839)
2012
14
Is gingival recession a consequence of an orthodontic tooth size and/or tooth position discrepancy? "A paradigm shift". (23738895)
2011
15
A two-stage approach using an autogenous masticatory mucosal graft and an autogenous connective tissue graft to treat gingival recession: a case report. (20465031)
2010
16
Coronally positioned flap with or without acellular dermal matrix graft in the treatment of class II gingival recession defects: A randomized controlled clinical study. (22114387)
2010
17
Classification of dental surface defects in areas of gingival recession. (20450362)
2010
18
Gingival recession, oral hygiene and associated factors among Tanzanian women. (19702100)
2009
19
Double laterally rotated bilayer flap operation for treatment of gingival recession: A report of two cases. (20142945)
2008
20
Subepithelial connective tissue graft in the treatment of multiple gingival recession. (17618142)
2007
21
Cross-sectional evaluation of the presence of gingival recession in individuals with cleft lip and palate. (17199536)
2007
22
Alveolar bone loss and gingival recession due to lip and tongue piercing. (17891882)
2007
23
Does tooth brushing influence the development and progression of non-inflammatory gingival recession? A systematic review. (17953693)
2007
24
Current trends in gingival recession coverage--part I: the tunnel connective tissue graft. (17001834)
2006
25
Clinical evaluation of a bioresorbable membrane (polyglactin 910) in the treatment of Miller type II gingival recession. (16836169)
2006
26
Acellular dermal matrix allograft used alone and in combination with enamel matrix protein in gingival recession: histologic study in dogs. (16353534)
2005
27
Treatment of gingival recession using a collagen membrane with or without the use of demineralized freeze-dried bone allograft for space maintenance. (15068108)
2004
28
Localized gingival recession caused by a C-PAP mask: a case report. (12451912)
2002
29
The extent and correlates of gingival recession in non-institutionalised Thai elderly. (12670095)
2002
30
The management of gingival recession. (12572201)
2002
31
Comparative 6-month clinical study of a subepithelial connective tissue graft and acellular dermal matrix graft for the treatment of gingival recession. (11759858)
2001
32
Treatment of gingival recession with collagen membranes. (12004684)
2001
33
An unusual cause of gingival recession: oral piercing. (11128927)
2000
34
Clinical and histologic evaluation of human gingival recession treated with a subepithelial connective tissue graft and enamel matrix derivative (Emdogain): a case report. (11203568)
2000
35
Treatment of gingival recession: comparative study between subepithelial connective tissue graft and guided tissue regeneration. (11022773)
2000
36
Subpedicle connective tissue graft versus guided tissue regeneration with bioabsorbable membrane in the treatment of human gingival recession defects. (9848537)
1998
37
Resorbable barrier and envelope flap surgery in the treatment of human gingival recession defects. Case reports. (9477016)
1998
38
Gingival recession: intra-oral distribution and associated factors. (7990024)
1994
39
The effect of an anticalculus dentifrice on supragingival calculus formation and gingival recession in Thai adults: a one-year study. (1667469)
1991
40
Occurrence of gingival recession in adults. (2600746)
1989
41
Improvement potential of isolated gingival recession in children. (3458318)
1986
42
A clinical study of localized gingival recession treated by lateral sliding flap. (3861708)
1985
43
Gingival recession in the mandibular central incisor region of Saudi schoolchildren aged 10-15 years. (6576884)
1983
44
The etiology of gingival recession. Review of literature. (392016)
1979
45
The prevalence and distribution of gingivitis and gingival recession in children and young adults in Lagos, Nigeria. (284116)
1979
46
Factors influencing gingival recession in the lower incisor region. (282597)
1977
47
Gingival recession in tooth types in high fluoride and low fluoride areas. (4269591)
1973
48
Gingivitis and gingival recession in adults from high-fluoride and low-fluoride areas. (4506980)
1972
49
The etiology of gingival recession. (5278610)
1971
50
An analysis of localized gingival recession in 766 Winnipeg High School students. (5218030)
1966

Variations for Gingival Recession

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Expression for genes affiliated with Gingival Recession

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Sources:
2BioGPS, 16Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Gingival Recession

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Pathways for genes affiliated with Gingival Recession

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Compounds for genes affiliated with Gingival Recession

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Sources:
46Novoseek, 12DrugBank, 52PharmGKB, 25HMDB, 62Tocris Bioscience
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Compounds related to Gingival Recession according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1benzalkonium chloride469.4DSPP, IL1A
2minocycline46 1210.4DSPP, IL1A
3ciprofloxacin46 52 1211.4IL1A, DSPP
4tetracycline46 1210.3DSPP, IL1A
5formaldehyde46 2510.3DSPP, IL1A
6calcitriol46 62 25 1212.3IL1A, DSPP
7epinephrine46 25 1211.2IL1A, DSPP
8aspartate469.2DSPP, IL1A
9ascorbic acid46 2510.1DSPP, IL1A
10vitamin d468.9IL1A, DSPP

GO Terms for genes affiliated with Gingival Recession

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17Gene Ontology
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Biological processes related to Gingival Recession according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1immune responseGO:0069559.0IL1A, CLNK

Products for genes affiliated with Gingival Recession

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Gingival Recession

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4CDC
14ExPASy
15FMA
23GTR
24HGMD
25HMDB
26ICD10
27ICD10 via Orphanet
28ICD9CM
30IUPHAR
31KEGG
36MeSH
37MESH via Orphanet
38MGI
41NCIt
42NDF-RT
45NINDS
46Novoseek
48OMIM
49OMIM via Orphanet
53PubMed
54QIAGEN
60SNOMED-CT via Orphanet
63UMLS
64UMLS via Orphanet