MCID: GLS012
MIFTS: 38

Glassy Cell Carcinoma of the Cervix malady

Rare diseases, Cancer diseases categories
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Summaries for Glassy Cell Carcinoma of the Cervix

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Wikipedia:65 Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour... more...

MalaCards based summary: Glassy Cell Carcinoma of the Cervix, also known as glassy cell adenocarcinoma of the uterine cervix, is related to glassy cell carcinoma of the cervix uteri and cerebral meningioma. An important gene associated with Glassy Cell Carcinoma of the Cervix is PGR (progesterone receptor), and among its related pathways are Nuclear signaling by ERBB4 and Cell cycle Regulation of G1 S transition part 2 . The compounds ici 164384 and idoxifene have been mentioned in the context of this disorder. Affiliated tissues include cervix and ovary, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Aliases & Classifications for Glassy Cell Carcinoma of the Cervix

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Glassy Cell Carcinoma of the Cervix, Aliases & Descriptions:

Name: Glassy Cell Carcinoma of the Cervix 42 62
Glassy Cell Adenocarcinoma of the Uterine Cervix 42 62
 
Gcc of the Cervix 42


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


Related Diseases for Glassy Cell Carcinoma of the Cervix

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Graphical network of the top 20 diseases related to Glassy Cell Carcinoma of the Cervix:



Diseases related to glassy cell carcinoma of the cervix

Symptoms for Glassy Cell Carcinoma of the Cervix

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Drugs & Therapeutics for Glassy Cell Carcinoma of the Cervix

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Drug clinical trials:

Search ClinicalTrials for Glassy Cell Carcinoma of the Cervix

Search NIH Clinical Center for Glassy Cell Carcinoma of the Cervix

Genetic Tests for Glassy Cell Carcinoma of the Cervix

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Anatomical Context for Glassy Cell Carcinoma of the Cervix

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MalaCards organs/tissues related to Glassy Cell Carcinoma of the Cervix:

32
Cervix, Ovary

Animal Models for Glassy Cell Carcinoma of the Cervix or affiliated genes

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MGI Mouse Phenotypes related to Glassy Cell Carcinoma of the Cervix:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.7ERBB2, ESR1, PGR
2MP:00020068.7ERBB2, ESR1, PGR
3MP:00053698.7PGR, ESR1, ERBB2
4MP:00053798.6ERBB2, ESR1, PGR
5MP:00053908.6PGR, ESR1, ERBB2
6MP:00107718.5ERBB2, ESR1, PGR
7MP:00053858.5ERBB2, ESR1, PGR
8MP:00053808.4PGR, ESR1, ERBB2
9MP:00053898.2ERBB2, ESR1, PGR

Publications for Glassy Cell Carcinoma of the Cervix

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Articles related to Glassy Cell Carcinoma of the Cervix:

(show all 21)
idTitleAuthorsYear
1
Glassy cell carcinoma of the cervix: a literature review. (24792540)
2014
2
Glassy Cell Carcinoma of the Cervix and Metastasis in Episiotomy Scar: A Case Report. (25062402)
2014
3
Glassy cell carcinoma of the cervix: a systematic review and meta-analysis. (24503463)
2014
4
Glassy cell carcinoma of the cervix--a case report with review of the literature. (22384631)
2011
5
Conservatively treated glassy cell carcinoma of the cervix. (18755015)
2008
6
Glassy cell carcinoma of the cervix: cytologic features and expression of estrogen receptor, progesterone receptor and Her2/neu protein. (16901007)
2006
7
Liquid-based cytology findings of glassy cell carcinoma of the cervix. Report of a case with histologic correlation and molecular analysis. (14969191)
2004
8
Glassy cell carcinoma of the cervix revisited. (11972387)
2002
9
Can glassy cell carcinoma of the cervix be diagnosed by Pap smear? (12462103)
2002
10
Response of glassy-cell carcinoma of the cervix to cisplatin, epirubicin, and mitomycin C. (10791384)
2000
11
Absence of estrogen and progesterone receptors in glassy cell carcinoma of the cervix. (9464737)
1998
12
Glassy cell carcinoma of the cervix: a bimodal treatment strategy. (1541437)
1992
13
Stage IB glassy cell carcinoma of the cervix diagnosed during pregnancy and recurring in a transposed ovary. (1916516)
1991
14
Glassy cell carcinoma of the cervix redefined. (3368169)
1988
15
Glassy cell carcinoma of the cervix. Cytologic and clinicopathologic analysis. (6861073)
1983
16
Glassy cell carcinoma of the cervix: report of three cases. (7120471)
1982
17
Glassy cell carcinoma of the cervix. (6296737)
1982
18
A clinicopathological study on glassy cell carcinoma of the cervix. (7234357)
1981
19
Glassy-cell carcinoma of the cervix: case report with a light and electron microscopy study. (7233592)
1980
20
Stage i B glassy cell carcinoma of the cervix with ovarian metastases. (858556)
1977
21
Glassy cell carcinoma of the cervix. (1260713)
1976

Variations for Glassy Cell Carcinoma of the Cervix

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Expression for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Expression patterns in normal tissues for genes affiliated with Glassy Cell Carcinoma of the Cervix

Search GEO for disease gene expression data for Glassy Cell Carcinoma of the Cervix.

Pathways for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Pathways related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3ESR1, PGR
2
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.3ESR1, PGR
3
Show member pathways
Nuclear Receptors37
9.3PGR, ESR1
4
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor37
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
9.1ERBB2, ESR1
59.1ERBB2, ESR1
69.1ERBB2, ESR1
7
Show member pathways
Development Ligand independent activation of ESR1 and ESR260
9.1ERBB2, ESR1
8
Show member pathways
Prolactin Signaling Pathway37
Development Prolactin receptor signaling60
Leptin signaling pathway37
9.1ESR1, ERBB2
9
Show member pathways
8.5ERBB2, ESR1, PGR
10
Show member pathways
8.5PGR, ESR1, ERBB2

Compounds for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Compounds related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1ici 164384449.8PGR, ESR1
2idoxifene449.7ESR1, PGR
3triphenylethylene449.7PGR, ESR1
4norgestimate44 1110.7PGR, ESR1
5medroxyprogesterone44 50 28 24 1113.7ESR1, PGR
6trilostane44 1110.7ESR1, PGR
7droloxifene449.7ESR1, PGR
8estradiol benzoate449.7PGR, ESR1
9nandrolone44 2410.7PGR, ESR1
10desogestrel44 1110.7PGR, ESR1
11onapristone44 2810.7PGR, ESR1
12goserelin44 28 1111.7PGR, ESR1
13nomegestrol acetate449.6PGR, ESR1
14leuprolide acetate449.6PGR, ESR1
15bisphenol a449.6PGR, ESR1
16fadrozole449.5ESR1, ERBB2
17clomiphene citrate449.5ESR1, PGR
18tibolone449.5PGR, ESR1
19danazol44 24 1111.4PGR, ESR1
20levonorgestrel44 61 28 1112.4PGR, ESR1
21everolimus44 50 1111.3ESR1, ERBB2
22steroidal449.3ESR1, PGR
23capecitabine44 50 1111.3ERBB2, PGR
24flutamide44 61 1111.2PGR, ESR1
25megestrol acetate449.0ERBB2, ESR1, PGR
26exemestane44 50 61 1112.0ESR1, PGR, ERBB2
27anastrozole44 50 1111.0ERBB2, PGR, ESR1
28lapatinib44 50 1111.0ESR1, PGR, ERBB2
29toremifene44 1110.0ERBB2, PGR, ESR1
30fulvestrant44 50 28 1111.9ESR1, ERBB2, PGR
31letrozole44 50 61 1111.9ESR1, ERBB2, PGR
32taxane448.9ESR1, ERBB2, PGR
33raloxifene44 50 28 1111.9PGR, ERBB2, ESR1
34trastuzumab44 50 1110.9ERBB2, PGR, ESR1
354-hydroxytamoxifen448.9PGR, ESR1, ERBB2
36progestin448.9ERBB2, PGR, ESR1
37geldanamycin44 50 61 1111.9PGR, ESR1, ERBB2
38resveratrol44 61 24 1111.9PGR, ESR1, ERBB2
39docetaxel44 50 61 1111.9ERBB2, ESR1, PGR
40cyclophosphamide44 50 1110.9PGR, ERBB2, ESR1
41gnrh448.9PGR, ESR1, ERBB2
42methotrexate50 44 1110.9ERBB2, ESR1, PGR
435fluorouracil448.9ERBB2, ESR1, PGR
44tamoxifen44 50 28 1111.9ERBB2, ESR1, PGR
45radicicol44 61 1110.8ERBB2, ESR1
46paclitaxel44 50 1110.8ERBB2, PGR, ESR1
47doxorubicin44 50 1110.8ERBB2, PGR, ESR1
48paraffin448.8ERBB2, ESR1, PGR
49genistein44 28 61 2 24 1113.7ESR1, ERBB2, PGR
50cycloheximide448.5PGR, ERBB2, ESR1

GO Terms for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Biological processes related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription initiation from RNA polymerase II promoterGO:0063679.3ESR1, PGR
2negative regulation of gene expressionGO:0106299.2ESR1, PGR
3signal transductionGO:0071658.2ERBB2, ESR1, PGR

Molecular functions related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:0198999.3ESR1, PGR
2steroid bindingGO:0054969.2ESR1, PGR
3steroid hormone receptor activityGO:0037079.0ESR1, PGR

Products for genes affiliated with Glassy Cell Carcinoma of the Cervix

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  • Antibodies
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Sources for Glassy Cell Carcinoma of the Cervix

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet