MCID: GLS012
MIFTS: 37

Glassy Cell Carcinoma of the Cervix malady

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Summaries for Glassy Cell Carcinoma of the Cervix

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65Wikipedia, 33MalaCards
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Wikipedia:65 Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour... more...

MalaCards: Glassy Cell Carcinoma of the Cervix, also known as glassy cell adenocarcinoma of the uterine cervix, is related to glassy cell carcinoma of the cervix uteri and cerebral meningioma. An important gene associated with Glassy Cell Carcinoma of the Cervix is PGR (progesterone receptor), and among its related pathways are Nuclear signaling by ERBB4 and Cell cycle Regulation of G1 S transition part 2 . The compounds ici 164384 and idoxifene have been mentioned in the context of this disorder. Affiliated tissues include cervix and ovary, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Aliases & Classifications for Glassy Cell Carcinoma of the Cervix

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43NIH Rare Diseases
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


Aliases & Descriptions:

glassy cell carcinoma of the cervix 43
glassy cell adenocarcinoma of the uterine cervix 43
gcc of the cervix 43


Related Diseases for Glassy Cell Carcinoma of the Cervix

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Glassy Cell Carcinoma of the Cervix:



Diseases related to glassy cell carcinoma of the cervix

Symptoms for Glassy Cell Carcinoma of the Cervix

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Drugs & Therapeutics for Glassy Cell Carcinoma of the Cervix

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42NIH Clinical Center, 6ClinicalTrials
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Drug clinical trials:

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Genetic Tests for Glassy Cell Carcinoma of the Cervix

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Anatomical Context for Glassy Cell Carcinoma of the Cervix

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33MalaCards
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MalaCards organs/tissues related to Glassy Cell Carcinoma of the Cervix:

33
Cervix, Ovary

Animal Models for Glassy Cell Carcinoma of the Cervix or affiliated genes

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37MGI
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MGI Mouse Phenotypes related to Glassy Cell Carcinoma of the Cervix:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.7ERBB2, ESR1, PGR
2MP:00020068.7ERBB2, ESR1, PGR
3MP:00053698.7PGR, ESR1, ERBB2
4MP:00053798.6ERBB2, ESR1, PGR
5MP:00053908.6PGR, ESR1, ERBB2
6MP:00107718.5ERBB2, ESR1, PGR
7MP:00053858.5ERBB2, ESR1, PGR
8MP:00053808.4PGR, ESR1, ERBB2
9MP:00053898.2ERBB2, ESR1, PGR

Publications for Glassy Cell Carcinoma of the Cervix

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52PubMed
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Articles related to Glassy Cell Carcinoma of the Cervix:

(show all 18)
idTitleAuthorsYear
1
Glassy cell carcinoma of the cervix--a case report with review of the literature. (22384631)
2011
2
Conservatively treated glassy cell carcinoma of the cervix. (18755015)
2008
3
Glassy cell carcinoma of the cervix: cytologic features and expression of estrogen receptor, progesterone receptor and Her2/neu protein. (16901007)
2006
4
Liquid-based cytology findings of glassy cell carcinoma of the cervix. Report of a case with histologic correlation and molecular analysis. (14969191)
2004
5
Glassy cell carcinoma of the cervix revisited. (11972387)
2002
6
Can glassy cell carcinoma of the cervix be diagnosed by Pap smear? (12462103)
2002
7
Response of glassy-cell carcinoma of the cervix to cisplatin, epirubicin, and mitomycin C. (10791384)
2000
8
Absence of estrogen and progesterone receptors in glassy cell carcinoma of the cervix. (9464737)
1998
9
Glassy cell carcinoma of the cervix: a bimodal treatment strategy. (1541437)
1992
10
Stage IB glassy cell carcinoma of the cervix diagnosed during pregnancy and recurring in a transposed ovary. (1916516)
1991
11
Glassy cell carcinoma of the cervix redefined. (3368169)
1988
12
Glassy cell carcinoma of the cervix. Cytologic and clinicopathologic analysis. (6861073)
1983
13
Glassy cell carcinoma of the cervix: report of three cases. (7120471)
1982
14
Glassy cell carcinoma of the cervix. (6296737)
1982
15
A clinicopathological study on glassy cell carcinoma of the cervix. (7234357)
1981
16
Glassy-cell carcinoma of the cervix: case report with a light and electron microscopy study. (7233592)
1980
17
Stage i B glassy cell carcinoma of the cervix with ovarian metastases. (858556)
1977
18
Glassy cell carcinoma of the cervix. (1260713)
1976

Variations for Glassy Cell Carcinoma of the Cervix

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Expression for genes affiliated with Glassy Cell Carcinoma of the Cervix

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2BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glassy Cell Carcinoma of the Cervix

Search GEO for disease gene expression data for Glassy Cell Carcinoma of the Cervix.

Pathways for genes affiliated with Glassy Cell Carcinoma of the Cervix

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50PathCards, 55Reactome, 60Thomson Reuters, 38NCBI BioSystems Database, 30KEGG
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Pathways related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3ESR1, PGR
2
Show member pathways
Cell cycle ESR1 regulation of G1 S transition60
Immune response MIF JAB1 signaling60
Cell cycle Cell cycle generic schema 60
9.3ESR1, PGR
3
Show member pathways
Nuclear Receptors38
9.3PGR, ESR1
4
Show member pathways
Development EGFR signaling via PIP360
Development PDGF signaling via MAPK cascades60
Apoptosis and survival Anti apoptotic action of membrane bound ESR160
Signaling of Hepatocyte Growth Factor Receptor38
Development EGFR signaling via small GTPases60
Development Neurotrophin family signaling60
Apoptosis and survival NGF signaling pathway60
Apoptosis and survival Role of CDK5 in neuronal death and survival60
9.1ERBB2, ESR1
59.1ERBB2, ESR1
69.1ERBB2, ESR1
7
Show member pathways
Development Ligand independent activation of ESR1 and ESR260
9.1ERBB2, ESR1
8
Show member pathways
Prolactin Signaling Pathway38
Development Prolactin receptor signaling60
Leptin signaling pathway38
9.1ESR1, ERBB2
9
Show member pathways
8.5ERBB2, ESR1, PGR
10
Show member pathways
8.5PGR, ESR1, ERBB2

Compounds for genes affiliated with Glassy Cell Carcinoma of the Cervix

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45Novoseek, 11DrugBank, 51PharmGKB, 29IUPHAR, 24HMDB, 61Tocris Bioscience, 3BitterDB
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Compounds related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1ici 164384459.8PGR, ESR1
2idoxifene459.7ESR1, PGR
3triphenylethylene459.7PGR, ESR1
4norgestimate45 1110.7PGR, ESR1
5medroxyprogesterone45 51 29 24 1113.7ESR1, PGR
6trilostane45 1110.7ESR1, PGR
7droloxifene459.7ESR1, PGR
8estradiol benzoate459.7PGR, ESR1
9nandrolone45 2410.7PGR, ESR1
10desogestrel45 1110.7PGR, ESR1
11onapristone45 2910.7PGR, ESR1
12goserelin45 29 1111.7PGR, ESR1
13nomegestrol acetate459.6PGR, ESR1
14leuprolide acetate459.6PGR, ESR1
15bisphenol a459.6PGR, ESR1
16fadrozole459.5ESR1, ERBB2
17clomiphene citrate459.5ESR1, PGR
18tibolone459.5PGR, ESR1
19danazol45 24 1111.4PGR, ESR1
20levonorgestrel45 61 29 1112.4PGR, ESR1
21everolimus45 51 1111.3ESR1, ERBB2
22steroidal459.3ESR1, PGR
23capecitabine45 51 1111.3ERBB2, PGR
24flutamide45 61 1111.2PGR, ESR1
25megestrol acetate459.0ERBB2, ESR1, PGR
26exemestane45 51 61 1112.0ESR1, PGR, ERBB2
27anastrozole45 51 1111.0ERBB2, PGR, ESR1
28lapatinib45 51 1111.0ESR1, PGR, ERBB2
29toremifene45 1110.0ERBB2, PGR, ESR1
30fulvestrant45 51 29 1111.9ESR1, ERBB2, PGR
31letrozole45 51 61 1111.9ESR1, ERBB2, PGR
32taxane458.9ESR1, ERBB2, PGR
33raloxifene45 51 29 1111.9PGR, ERBB2, ESR1
34trastuzumab45 51 1110.9ERBB2, PGR, ESR1
354-hydroxytamoxifen458.9PGR, ESR1, ERBB2
36progestin458.9ERBB2, PGR, ESR1
37geldanamycin45 51 61 1111.9PGR, ESR1, ERBB2
38resveratrol45 61 24 1111.9PGR, ESR1, ERBB2
39docetaxel45 51 61 1111.9ERBB2, ESR1, PGR
40cyclophosphamide45 51 1110.9PGR, ERBB2, ESR1
41gnrh458.9PGR, ESR1, ERBB2
42methotrexate51 45 1110.9ERBB2, ESR1, PGR
435fluorouracil458.9ERBB2, ESR1, PGR
44tamoxifen45 51 29 1111.9ERBB2, ESR1, PGR
45radicicol45 61 1110.8ERBB2, ESR1
46paclitaxel45 51 1110.8ERBB2, PGR, ESR1
47doxorubicin45 51 1110.8ERBB2, PGR, ESR1
48paraffin458.8ERBB2, ESR1, PGR
49genistein45 29 61 3 24 1113.7ESR1, ERBB2, PGR
50cycloheximide458.5PGR, ERBB2, ESR1

GO Terms for genes affiliated with Glassy Cell Carcinoma of the Cervix

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16Gene Ontology
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Biological processes related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1transcription initiation from RNA polymerase II promoterGO:0063679.3ESR1, PGR
2negative regulation of gene expressionGO:0106299.2ESR1, PGR
3signal transductionGO:0071658.2ERBB2, ESR1, PGR

Molecular functions related to Glassy Cell Carcinoma of the Cervix according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:0198999.3ESR1, PGR
2steroid bindingGO:0054969.2ESR1, PGR
3steroid hormone receptor activityGO:0037079.0ESR1, PGR

Products for genes affiliated with Glassy Cell Carcinoma of the Cervix

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  • Antibodies
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Sources for Glassy Cell Carcinoma of the Cervix

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4CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
59SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet