MCID: GLS012
MIFTS: 32

Glassy Cell Carcinoma of the Cervix malady

Rare diseases, Cancer diseases categories

Aliases & Classifications for Glassy Cell Carcinoma of the Cervix

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Glassy Cell Carcinoma of the Cervix, Aliases & Descriptions:

Name: Glassy Cell Carcinoma of the Cervix 41 60
Glassy Cell Adenocarcinoma of the Uterine Cervix 41
 
Gcc of the Cervix 41


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases, Cancer diseases


Summaries for Glassy Cell Carcinoma of the Cervix

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Wikipedia:63 Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour... more...

MalaCards based summary: Glassy Cell Carcinoma of the Cervix, also known as glassy cell adenocarcinoma of the uterine cervix, is related to glassy cell carcinoma of the cervix uteri and cerebral meningioma. An important gene associated with Glassy Cell Carcinoma of the Cervix is PGR (progesterone receptor), and among its related pathways are Nuclear signaling by ERBB4 and Cell cycle Regulation of G1 S transition part 2 . The compounds ici 164384 and idoxifene have been mentioned in the context of this disorder. Affiliated tissues include cervix and ovary, and related mouse phenotypes are limbs/digits/tail and tumorigenesis.

Related Diseases for Glassy Cell Carcinoma of the Cervix

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Graphical network of the top 20 diseases related to Glassy Cell Carcinoma of the Cervix:



Diseases related to glassy cell carcinoma of the cervix

Symptoms for Glassy Cell Carcinoma of the Cervix

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Drugs & Therapeutics for Glassy Cell Carcinoma of the Cervix

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Drug clinical trials:

Search ClinicalTrials for Glassy Cell Carcinoma of the Cervix

Search NIH Clinical Center for Glassy Cell Carcinoma of the Cervix

Genetic Tests for Glassy Cell Carcinoma of the Cervix

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Anatomical Context for Glassy Cell Carcinoma of the Cervix

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MalaCards organs/tissues related to Glassy Cell Carcinoma of the Cervix:

31
Cervix, Ovary

Animal Models for Glassy Cell Carcinoma of the Cervix or affiliated genes

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MGI Mouse Phenotypes related to Glassy Cell Carcinoma of the Cervix:

35
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053718.7ERBB2, ESR1, PGR
2MP:00020068.7ERBB2, ESR1, PGR
3MP:00053698.7PGR, ESR1, ERBB2
4MP:00053798.6ERBB2, ESR1, PGR
5MP:00053908.6PGR, ESR1, ERBB2
6MP:00107718.5ERBB2, ESR1, PGR
7MP:00053858.5ERBB2, ESR1, PGR
8MP:00053808.4PGR, ESR1, ERBB2
9MP:00053898.2ERBB2, ESR1, PGR

Publications for Glassy Cell Carcinoma of the Cervix

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Articles related to Glassy Cell Carcinoma of the Cervix:

(show all 21)
idTitleAuthorsYear
1
Glassy cell carcinoma of the cervix: a literature review. (24792540)
2014
2
Glassy Cell Carcinoma of the Cervix and Metastasis in Episiotomy Scar: A Case Report. (25062402)
2014
3
Glassy cell carcinoma of the cervix: a systematic review and meta-analysis. (24503463)
2014
4
Glassy cell carcinoma of the cervix--a case report with review of the literature. (22384631)
2011
5
Conservatively treated glassy cell carcinoma of the cervix. (18755015)
2008
6
Glassy cell carcinoma of the cervix: cytologic features and expression of estrogen receptor, progesterone receptor and Her2/neu protein. (16901007)
2006
7
Liquid-based cytology findings of glassy cell carcinoma of the cervix. Report of a case with histologic correlation and molecular analysis. (14969191)
2004
8
Glassy cell carcinoma of the cervix revisited. (11972387)
2002
9
Can glassy cell carcinoma of the cervix be diagnosed by Pap smear? (12462103)
2002
10
Response of glassy-cell carcinoma of the cervix to cisplatin, epirubicin, and mitomycin C. (10791384)
2000
11
Absence of estrogen and progesterone receptors in glassy cell carcinoma of the cervix. (9464737)
1998
12
Glassy cell carcinoma of the cervix: a bimodal treatment strategy. (1541437)
1992
13
Stage IB glassy cell carcinoma of the cervix diagnosed during pregnancy and recurring in a transposed ovary. (1916516)
1991
14
Glassy cell carcinoma of the cervix redefined. (3368169)
1988
15
Glassy cell carcinoma of the cervix. Cytologic and clinicopathologic analysis. (6861073)
1983
16
Glassy cell carcinoma of the cervix: report of three cases. (7120471)
1982
17
Glassy cell carcinoma of the cervix. (6296737)
1982
18
A clinicopathological study on glassy cell carcinoma of the cervix. (7234357)
1981
19
Glassy-cell carcinoma of the cervix: case report with a light and electron microscopy study. (7233592)
1980
20
Stage i B glassy cell carcinoma of the cervix with ovarian metastases. (858556)
1977
21
Glassy cell carcinoma of the cervix. (1260713)
1976

Variations for Glassy Cell Carcinoma of the Cervix

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Cosmic variations for Glassy Cell Carcinoma of the Cervix:

7 (show all 30)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Conf
1532KRAScervix,NS,carcinoma,adenocarcinoma3
2518KRAScervix,NS,carcinoma,adenocarcinoma3
3551KRAScervix,NS,carcinoma,adenocarcinoma3
4555KRAScervix,NS,carcinoma,adenocarcinoma3
5522KRAScervix,NS,carcinoma,adenocarcinoma3
6517KRAScervix,NS,carcinoma,adenocarcinoma3
7521KRAScervix,NS,carcinoma,adenocarcinoma3
8520KRAScervix,NS,carcinoma,adenocarcinoma3
9516KRAScervix,NS,carcinoma,adenocarcinoma3
10759PIK3CAcervix,NS,carcinoma,adenocarcinoma3
11746PIK3CAcervix,NS,carcinoma,adenocarcinoma3
126147PIK3CAcervix,NS,carcinoma,adenocarcinoma3
1329313PIK3CAcervix,NS,carcinoma,adenocarcinoma3
14763PIK3CAcervix,NS,carcinoma,adenocarcinoma3
15775PIK3CAcervix,NS,carcinoma,adenocarcinoma3
1624712PIK3CAcervix,NS,carcinoma,adenocarcinoma3
17760PIK3CAcervix,NS,carcinoma,adenocarcinoma3
1810785TP53cervix,NS,carcinoma,adenocarcinoma3
1944401TP53cervix,NS,carcinoma,adenocarcinoma3
2010656TP53cervix,NS,carcinoma,adenocarcinoma3
2110725TP53cervix,NS,carcinoma,adenocarcinoma3
2244399TP53cervix,NS,carcinoma,adenocarcinoma3
23461BRAFcervix,NS,carcinoma,adenocarcinoma3
24451BRAFcervix,NS,carcinoma,adenocarcinoma3
25470BRAFcervix,NS,carcinoma,adenocarcinoma3
2626506BRAFcervix,NS,carcinoma,adenocarcinoma3
2729468STK11cervix,NS,carcinoma,adenocarcinoma3
2829467STK11cervix,NS,carcinoma,adenocarcinoma3
295056PTENcervix,NS,carcinoma,adenocarcinoma3
30480HRAScervix,NS,carcinoma,adenocarcinoma3

Expression for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Search GEO for disease gene expression data for Glassy Cell Carcinoma of the Cervix.

Pathways for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Pathways related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Show member pathways
9.3ESR1, PGR
2
Show member pathways
Cell cycle ESR1 regulation of G1 S transition58
Immune response MIF JAB1 signaling58
Cell cycle Cell cycle generic schema 58
9.3ESR1, PGR
3
Show member pathways
Nuclear Receptors36
9.3PGR, ESR1
4
Show member pathways
Development EGFR signaling via PIP358
Development PDGF signaling via MAPK cascades58
Apoptosis and survival Anti apoptotic action of membrane bound ESR158
Signaling of Hepatocyte Growth Factor Receptor36
Development EGFR signaling via small GTPases58
Development Neurotrophin family signaling58
Apoptosis and survival NGF signaling pathway58
Apoptosis and survival Role of CDK5 in neuronal death and survival58
9.1ERBB2, ESR1
59.1ERBB2, ESR1
69.1ERBB2, ESR1
7
Show member pathways
Development Ligand independent activation of ESR1 and ESR258
9.1ERBB2, ESR1
8
Show member pathways
Prolactin Signaling Pathway36
Development Prolactin receptor signaling58
Leptin signaling pathway36
9.1ESR1, ERBB2
9
Show member pathways
8.5ERBB2, ESR1, PGR
10
Show member pathways
8.5PGR, ESR1, ERBB2

Compounds for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Compounds related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

(show top 50)    (show all 73)
idCompoundScoreTop Affiliating Genes
1ici 164384439.8ESR1, PGR
2idoxifene439.7ESR1, PGR
3triphenylethylene439.7PGR, ESR1
4norgestimate43 1210.7ESR1, PGR
5medroxyprogesterone43 49 28 24 1213.7ESR1, PGR
6trilostane43 1210.7PGR, ESR1
7nandrolone43 2410.7ESR1, PGR
8estradiol benzoate439.7ESR1, PGR
9droloxifene439.7ESR1, PGR
10onapristone43 2810.7ESR1, PGR
11desogestrel43 1210.7ESR1, PGR
12goserelin43 28 1211.7ESR1, PGR
13nomegestrol acetate439.6ESR1, PGR
14leuprolide acetate439.6PGR, ESR1
15bisphenol a439.6ESR1, PGR
16fadrozole439.5ESR1, ERBB2
17clomiphene citrate439.5ESR1, PGR
18tibolone439.5PGR, ESR1
19danazol43 24 1211.4ESR1, PGR
20levonorgestrel43 59 28 1212.4ESR1, PGR
21everolimus43 49 1211.3ERBB2, ESR1
22steroidal439.3ESR1, PGR
23capecitabine43 49 1211.3PGR, ERBB2
24flutamide43 59 1211.2ESR1, PGR
25megestrol acetate439.0ERBB2, ESR1, PGR
26anastrozole43 49 1211.0PGR, ESR1, ERBB2
27exemestane43 49 59 1212.0PGR, ESR1, ERBB2
28lapatinib43 49 1211.0PGR, ESR1, ERBB2
29toremifene43 1210.0ERBB2, ESR1, PGR
30fulvestrant43 49 28 1211.9PGR, ESR1, ERBB2
31letrozole43 49 59 1211.9ERBB2, ESR1, PGR
32taxane438.9ERBB2, ESR1, PGR
33raloxifene43 49 28 1211.9PGR, ESR1, ERBB2
34trastuzumab43 49 1210.9ERBB2, ESR1, PGR
354-hydroxytamoxifen438.9PGR, ESR1, ERBB2
36progestin438.9ERBB2, ESR1, PGR
37geldanamycin43 49 59 1211.9PGR, ESR1, ERBB2
38resveratrol43 59 24 1211.9ERBB2, ESR1, PGR
39docetaxel43 49 59 1211.9ERBB2, ESR1, PGR
40cyclophosphamide43 49 1210.9ERBB2, ESR1, PGR
41gnrh438.9ERBB2, ESR1, PGR
42methotrexate49 43 1210.9PGR, ESR1, ERBB2
435fluorouracil438.9ERBB2, ESR1, PGR
44tamoxifen43 49 28 1211.9PGR, ESR1, ERBB2
45radicicol43 59 1210.8ERBB2, ESR1
46paclitaxel43 49 1210.8PGR, ESR1, ERBB2
47doxorubicin43 49 1210.8ERBB2, ESR1, PGR
48paraffin438.8ERBB2, ESR1, PGR
49genistein43 28 59 2 24 1213.7PGR, ESR1, ERBB2
50cycloheximide438.5PGR, ESR1, ERBB2

GO Terms for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Biological processes related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1transcription initiation from RNA polymerase II promoterGO:00063679.3ESR1, PGR
2negative regulation of gene expressionGO:00106299.2ESR1, PGR
3signal transductionGO:00071658.2ERBB2, ESR1, PGR

Molecular functions related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1enzyme bindingGO:00198999.3ESR1, PGR
2steroid bindingGO:00054969.2ESR1, PGR
3steroid hormone receptor activityGO:00037079.0ESR1, PGR

Products for genes affiliated with Glassy Cell Carcinoma of the Cervix

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Sources for Glassy Cell Carcinoma of the Cervix

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
33MeSH
34MESH via Orphanet
35MGI
38NCIt
39NDF-RT
42NINDS
43Novoseek
45OMIM
46OMIM via Orphanet
50PubMed
51QIAGEN
56SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet