MCID: GLS012
MIFTS: 27

Glassy Cell Carcinoma of the Cervix malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Glassy Cell Carcinoma of the Cervix

Aliases & Descriptions for Glassy Cell Carcinoma of the Cervix:

Name: Glassy Cell Carcinoma of the Cervix 50
Glassy Cell Adenocarcinoma of the Uterine Cervix 50
Gcc of the Cervix 50

Classifications:



Summaries for Glassy Cell Carcinoma of the Cervix

MalaCards based summary : Glassy Cell Carcinoma of the Cervix, also known as glassy cell adenocarcinoma of the uterine cervix, is related to glassy cell carcinoma of the cervix uteri and bartholin's gland benign neoplasm. An important gene associated with Glassy Cell Carcinoma of the Cervix is PGR (Progesterone Receptor), and among its related pathways/superpathways are Glioma and Development Ligand-independent activation of ESR1 and ESR2. Affiliated tissues include cervix and ovary, and related phenotypes are limbs/digits/tail and muscle

Wikipedia : 71 Glassy cell carcinoma of the cervix, also glassy cell carcinoma, is a rare aggressive malignant tumour... more...

Related Diseases for Glassy Cell Carcinoma of the Cervix

Diseases related to Glassy Cell Carcinoma of the Cervix via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 109)
id Related Disease Score Top Affiliating Genes
1 glassy cell carcinoma of the cervix uteri 12.2
2 bartholin's gland benign neoplasm 10.1 ESR1 PGR
3 cardiovascular organ benign neoplasm 10.1 ESR1 PGR
4 appendix leiomyoma 10.1 ESR1 PGR
5 bronchus adenoma 10.1 ESR1 PGR
6 ovarian benign neoplasm 10.1 ESR1 PGR
7 plexiform neurofibroma 10.1 ESR1 PGR
8 paranasal sinus disease 10.1 ESR1 PGR
9 deafness, autosomal recessive 21 10.1 ESR1 PGR
10 atypical lipomatous tumor 10.1 ESR1 PGR
11 pediatric intraocular retinoblastoma 10.1 ESR1 PGR
12 congenital disorder of glycosylation, type ic 10.1 ESR1 PGR
13 intestinal perforation 10.1 ESR1 PGR
14 perlman syndrome 10.1 ESR1 PGR
15 bladder adenocarcinoma 10.1 ESR1 PGR
16 anal neuroendocrine tumor 10.1 ESR1 PGR
17 osteogenesis imperfecta 10.1 ESR1 PGR
18 vulva basal cell carcinoma 10.1 ESR1 PGR
19 villoglandular endometrial endometrioid adenocarcinoma 10.1 ESR1 PGR
20 vaginal adenosarcoma 10.1 ESR1 PGR
21 intraneural perineurioma 10.1 ESR1 PGR
22 middle ear adenocarcinoma 10.1 ESR1 PGR
23 paraphimosis 10.1 ESR1 PGR
24 acute thyroiditis 10.1 ESR1 PGR
25 mucoepidermoid esophageal carcinoma 10.1 ESR1 PGR
26 perinatal jaundice due to hepatocellular damage 10.1 ESR1 PGR
27 deafness, autosomal recessive 74 10.1 ESR1 PGR
28 adult neuronal ceroid lipofuscinosis 10.1 ESR1 PGR
29 vulvar alveolar soft part sarcoma 10.1 ESR1 PGR
30 ovarian clear cell malignant adenofibroma 10.1 ESR1 PGR
31 pilar sheath acanthoma 10.1 ESR1 PGR
32 osteoblastoma 10.1 ESR1 PGR
33 esophagus sarcoma 10.1 ESR1 PGR
34 lung clear cell carcinoma 10.0 ESR1 PGR
35 migraine with aura 10.0 ESR1 PGR
36 biliary tract neoplasm 10.0 ESR1 PGR
37 epithelioid neurofibroma 10.0 ESR1 PGR
38 gangliosidosis gm1 10.0 ESR1 PGR
39 capillary disease 10.0 ESR1 PGR
40 haverhill fever 10.0 ESR1 PGR
41 glycerol kinase deficiency, adult form 10.0 ESR1 PGR
42 hereditary breast ovarian cancer 10.0 ERBB2 ESR1
43 peeling skin syndrome 10.0 ESR1 PGR
44 nephrogenic adenofibroma 10.0 ESR1 PGR
45 substance abuse 10.0 ERBB2 ESR1
46 mouth disease 10.0 ERBB2 PGR
47 spondylolysis 10.0 ESR1 PGR
48 mucoepidermoid thyroid carcinoma 10.0 ERBB2 PGR
49 triple-receptor negative breast cancer 10.0 ERBB2 PGR
50 skin sarcoma 10.0 ERBB2 PGR

Graphical network of the top 20 diseases related to Glassy Cell Carcinoma of the Cervix:



Diseases related to Glassy Cell Carcinoma of the Cervix

Symptoms & Phenotypes for Glassy Cell Carcinoma of the Cervix

MGI Mouse Phenotypes related to Glassy Cell Carcinoma of the Cervix:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 limbs/digits/tail MP:0005371 9.33 ERBB2 ESR1 PGR
2 muscle MP:0005369 9.13 ERBB2 ESR1 PGR
3 neoplasm MP:0002006 8.8 ERBB2 ESR1 PGR

Drugs & Therapeutics for Glassy Cell Carcinoma of the Cervix

Search Clinical Trials , NIH Clinical Center for Glassy Cell Carcinoma of the Cervix

Genetic Tests for Glassy Cell Carcinoma of the Cervix

Anatomical Context for Glassy Cell Carcinoma of the Cervix

MalaCards organs/tissues related to Glassy Cell Carcinoma of the Cervix:

39
Cervix, Ovary

Publications for Glassy Cell Carcinoma of the Cervix

Articles related to Glassy Cell Carcinoma of the Cervix:

(show all 22)
id Title Authors Year
1
Molecular Genetic Profiling of Adolescent Glassy Cell Carcinoma of the Cervix Reveals Targetable EGFR Amplification with Potential Therapeutic Implications. ( 26974246 )
2016
2
Glassy cell carcinoma of the cervix: a literature review. ( 24792540 )
2014
3
Glassy Cell Carcinoma of the Cervix and Metastasis in Episiotomy Scar: A Case Report. ( 25062402 )
2014
4
Glassy cell carcinoma of the cervix: a systematic review and meta-analysis. ( 24503463 )
2014
5
Glassy cell carcinoma of the cervix--a case report with review of the literature. ( 22384631 )
2011
6
Conservatively treated glassy cell carcinoma of the cervix. ( 18755015 )
2008
7
Glassy cell carcinoma of the cervix: cytologic features and expression of estrogen receptor, progesterone receptor and Her2/neu protein. ( 16901007 )
2006
8
Liquid-based cytology findings of glassy cell carcinoma of the cervix. Report of a case with histologic correlation and molecular analysis. ( 14969191 )
2004
9
Glassy cell carcinoma of the cervix revisited. ( 11972387 )
2002
10
Can glassy cell carcinoma of the cervix be diagnosed by Pap smear? ( 12462103 )
2002
11
Response of glassy-cell carcinoma of the cervix to cisplatin, epirubicin, and mitomycin C. ( 10791384 )
2000
12
Absence of estrogen and progesterone receptors in glassy cell carcinoma of the cervix. ( 9464737 )
1998
13
Glassy cell carcinoma of the cervix: a bimodal treatment strategy. ( 1541437 )
1992
14
Stage IB glassy cell carcinoma of the cervix diagnosed during pregnancy and recurring in a transposed ovary. ( 1916516 )
1991
15
Glassy cell carcinoma of the cervix redefined. ( 3368169 )
1988
16
Glassy cell carcinoma of the cervix. Cytologic and clinicopathologic analysis. ( 6861073 )
1983
17
Glassy cell carcinoma of the cervix. ( 6296737 )
1982
18
Glassy cell carcinoma of the cervix: report of three cases. ( 7120471 )
1982
19
A clinicopathological study on glassy cell carcinoma of the cervix. ( 7234357 )
1981
20
Glassy-cell carcinoma of the cervix: case report with a light and electron microscopy study. ( 7233592 )
1980
21
Stage i B glassy cell carcinoma of the cervix with ovarian metastases. ( 858556 )
1977
22
Glassy cell carcinoma of the cervix. ( 1260713 )
1976

Variations for Glassy Cell Carcinoma of the Cervix

Cosmic variations for Glassy Cell Carcinoma of the Cervix:

9 (show all 44)
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM10725 TP53 cervix,NS,carcinoma,adenocarcinoma c.701A>G p.Y234C 15
2 COSM11333 TP53 cervix,NS,carcinoma,adenocarcinoma c.499C>T p.Q167* 15
3 COSM10656 TP53 cervix,NS,carcinoma,adenocarcinoma c.742C>T p.R248W 15
4 COSM44399 TP53 cervix,NS,carcinoma,adenocarcinoma c.677G>T p.G226V 15
5 COSM10662 TP53 cervix,NS,carcinoma,adenocarcinoma c.743G>A p.R248Q 15
6 COSM29468 STK11 cervix,NS,carcinoma,adenocarcinoma c.910C>T p.R304W 15
7 COSM29467 STK11 cervix,NS,carcinoma,adenocarcinoma c.894C>A p.F298L 15
8 COSM5219 PTEN cervix,NS,carcinoma,adenocarcinoma c.388C>G p.R130G 15
9 COSM5056 PTEN cervix,NS,carcinoma,adenocarcinoma c.1093G>A p.V365I 15
10 COSM5152 PTEN cervix,NS,carcinoma,adenocarcinoma c.388C>T p.R130* 15
11 COSM5154 PTEN cervix,NS,carcinoma,adenocarcinoma c.697C>T p.R233* 15
12 COSM88109 PTEN cervix,NS,carcinoma,adenocarcinoma c.724G>T p.E242* 15
13 COSM27133 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1633G>C p.E545Q 15
14 COSM759 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1616C>G p.P539R 15
15 COSM763 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1633G>A p.E545K 15
16 COSM775 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.3140A>G p.H1047R 15
17 COSM746 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.263G>A p.R88Q 15
18 COSM24712 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1638G>T p.Q546H 15
19 COSM12584 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1357G>A p.E453K 15
20 COSM760 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1624G>A p.E542K 15
21 COSM29313 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.3129G>A p.M1043I 15
22 COSM6147 PIK3CA cervix,NS,carcinoma,adenocarcinoma c.1636C>G p.Q546E 15
23 COSM584 NRAS cervix,NS,carcinoma,adenocarcinoma c.182A>G p.Q61R 15
24 COSM517 KRAS cervix,NS,carcinoma,adenocarcinoma c.34G>A p.G12S 15
25 COSM521 KRAS cervix,NS,carcinoma,adenocarcinoma c.35G>A p.G12D 15
26 COSM532 KRAS cervix,NS,carcinoma,adenocarcinoma c.38G>A p.G13D 15
27 COSM516 KRAS cervix,NS,carcinoma,adenocarcinoma c.34G>T p.G12C 15
28 COSM522 KRAS cervix,NS,carcinoma,adenocarcinoma c.35G>C p.G12A 15
29 COSM520 KRAS cervix,NS,carcinoma,adenocarcinoma c.35G>T p.G12V 15
30 COSM551 KRAS cervix,NS,carcinoma,adenocarcinoma c.182A>C p.Q61P 15
31 COSM555 KRAS cervix,NS,carcinoma,adenocarcinoma c.183A>T p.Q61H 15
32 COSM518 KRAS cervix,NS,carcinoma,adenocarcinoma c.34G>C p.G12R 15
33 COSM480 HRAS cervix,NS,carcinoma,adenocarcinoma c.34G>A p.G12S 15
34 COSM22975 FBXW7 cervix,NS,carcinoma,adenocarcinoma c.1513C>T p.R505C 15
35 COSM420169 FBXW7 cervix,NS,carcinoma,adenocarcinoma c.1436G>C p.R479P 15
36 COSM94225 ERBB2 cervix,NS,carcinoma,adenocarcinoma c.929C>A p.S310Y 15
37 COSM48358 ERBB2 cervix,NS,carcinoma,adenocarcinoma c.929C>T p.S310F 15
38 COSM5683 CTNNB1 cervix,NS,carcinoma,adenocarcinoma c.97T>G p.S33A 15
39 COSM5662 CTNNB1 cervix,NS,carcinoma,adenocarcinoma c.110C>T p.S37F 15
40 COSM461 BRAF cervix,NS,carcinoma,adenocarcinoma c.1406G>A p.G469E 15
41 COSM26506 BRAF cervix,NS,carcinoma,adenocarcinoma c.1787G>A p.G596D 15
42 COSM470 BRAF cervix,NS,carcinoma,adenocarcinoma c.1789C>G p.L597V 15
43 COSM451 BRAF cervix,NS,carcinoma,adenocarcinoma c.1397G>T p.G466V 15
44 COSM5369888 ALK cervix,NS,carcinoma,adenocarcinoma c.1396G>A p.D466N 15

Expression for Glassy Cell Carcinoma of the Cervix

Search GEO for disease gene expression data for Glassy Cell Carcinoma of the Cervix.

Pathways for Glassy Cell Carcinoma of the Cervix

Pathways related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.99 ERBB2 ESR1 PGR
2
Show member pathways
11.73 ERBB2 ESR1
3 11.68 ERBB2 ESR1
4
Show member pathways
11.57 ESR1 PGR
5
Show member pathways
11.23 ERBB2 ESR1
6
Show member pathways
11.11 ESR1 PGR
7
Show member pathways
10.83 ERBB2 ESR1 PGR

GO Terms for Glassy Cell Carcinoma of the Cervix

Biological processes related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression GO:0010629 9.16 ESR1 PGR
2 transcription initiation from RNA polymerase II promoter GO:0006367 8.96 ESR1 PGR
3 steroid hormone mediated signaling pathway GO:0043401 8.62 ESR1 PGR

Molecular functions related to Glassy Cell Carcinoma of the Cervix according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 ATPase binding GO:0051117 9.26 ESR1 PGR
2 steroid hormone receptor activity GO:0003707 9.16 ESR1 PGR
3 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding GO:0004879 8.96 ESR1 PGR
4 steroid binding GO:0005496 8.62 ESR1 PGR

Sources for Glassy Cell Carcinoma of the Cervix

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
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43 MESH via Orphanet
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48 NDF-RT
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54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
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70 UMLS via Orphanet
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