MCID: GLC051
MIFTS: 12

Glaucoma 1, Open Angle, M

Categories: Genetic diseases

Aliases & Classifications for Glaucoma 1, Open Angle, M

MalaCards integrated aliases for Glaucoma 1, Open Angle, M:

Name: Glaucoma 1, Open Angle, M 53 28 13 69
Glc1m 53

Characteristics:

OMIM:

53
Inheritance:
autosomal dominant

Miscellaneous:
age of onset/diagnosis 12-35 years


HPO:

31
glaucoma 1, open angle, m:
Inheritance autosomal dominant inheritance


Classifications:



External Ids:

OMIM 53 610535
MedGen 39 C1864653
UMLS 69 C1864653

Summaries for Glaucoma 1, Open Angle, M

MalaCards based summary : Glaucoma 1, Open Angle, M, is also known as glc1m, and has symptoms including constriction of peripheral visual field and open angle glaucoma. An important gene associated with Glaucoma 1, Open Angle, M is GLC1M (Glaucoma 1, Open Angle, M (Juvenile-Onset)).

Description from OMIM: 610535

Related Diseases for Glaucoma 1, Open Angle, M

Symptoms & Phenotypes for Glaucoma 1, Open Angle, M

Symptoms via clinical synopsis from OMIM:

53
Head And Neck Eyes:
anterior chamber angle open with grade iii-iv gonioscopy
bilateral intraocular pressures greater than or equal to 22 mmhg
vertical cup-to-disc ratio greater than or equal to 0.7
disc hemorrhage
thin or notched neuroretinal rim
more

Clinical features from OMIM:

610535

Human phenotypes related to Glaucoma 1, Open Angle, M:

31
# Description HPO Frequency HPO Source Accession
1 constriction of peripheral visual field 31 HP:0001133
2 open angle glaucoma 31 HP:0012108

Drugs & Therapeutics for Glaucoma 1, Open Angle, M

Search Clinical Trials , NIH Clinical Center for Glaucoma 1, Open Angle, M

Genetic Tests for Glaucoma 1, Open Angle, M

Genetic tests related to Glaucoma 1, Open Angle, M:

# Genetic test Affiliating Genes
1 Glaucoma 1, Open Angle, M 28

Anatomical Context for Glaucoma 1, Open Angle, M

Publications for Glaucoma 1, Open Angle, M

Articles related to Glaucoma 1, Open Angle, M:

# Title Authors Year
1
Fine mapping of new glaucoma locus GLC1M and exclusion of neuregulin 2 as the causative gene. ( 17563728 )
2007

Variations for Glaucoma 1, Open Angle, M

Expression for Glaucoma 1, Open Angle, M

Search GEO for disease gene expression data for Glaucoma 1, Open Angle, M.

Pathways for Glaucoma 1, Open Angle, M

GO Terms for Glaucoma 1, Open Angle, M

Sources for Glaucoma 1, Open Angle, M

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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