MCID: GLC030
MIFTS: 24

Glaucoma, Congenital malady

Summaries for Glaucoma, Congenital

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32MalaCards
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MalaCards: Glaucoma, Congenital is related to glaucoma and glaucoma 3, primary congenital, d. An important gene associated with Glaucoma, Congenital is FOXC1 (forkhead box C1), and among its related pathways is Transcriptional Regulatory Network in Embryonic Stem Cell. The compounds quinone and theophylline have been mentioned in the context of this disorder. Related mouse phenotypes are pigmentation and vision/eye.

Aliases & Classifications for Glaucoma, Congenital

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42NIH Rare Diseases, 22GTR, 44Novoseek
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Aliases & Descriptions:

glaucoma, congenital 42 22 44


Related Diseases for Glaucoma, Congenital

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17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Glaucoma, Congenital:



Diseases related to glaucoma, congenital

Clinical Features for Glaucoma, Congenital

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Drugs & Therapeutics for Glaucoma, Congenital

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Glaucoma, Congenital

Drug clinical trials:

Search ClinicalTrials for Glaucoma, Congenital

Search NIH Clinical Center for Glaucoma, Congenital

Search CenterWatch for Glaucoma, Congenital

Genetic Tests for Glaucoma, Congenital

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22GTR
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Genetic tests related to Glaucoma, Congenital:

id Genetic test Affiliating Genes
1 Glaucoma, Congenital22

Anatomical Context for Glaucoma, Congenital

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Animal Models for Glaucoma, Congenital or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Glaucoma, Congenital:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00011868.7PAX6, TYR, FOXC1
2MP:00053917.3PAX6, CYP1B1, TYR, MYOC, FOXC1

Publications for Glaucoma, Congenital

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Genetic Variations for Glaucoma, Congenital

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Expression for genes affiliated with Glaucoma, Congenital

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glaucoma, Congenital

Search GEO for disease gene expression data for Glaucoma, Congenital.

Pathways for genes affiliated with Glaucoma, Congenital

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51QIAGEN
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Pathways related to Glaucoma, Congenital according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.2PAX6, FOXC1

Compounds for genes affiliated with Glaucoma, Congenital

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44Novoseek, 24HMDB, 28IUPHAR, 11DrugBank, 59Tocris Bioscience, 49PharmGKB
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Compounds related to Glaucoma, Congenital according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1quinone44 2410.4CYP1B1, TYR
2theophylline44 28 11 2412.3CYP1B1, TYR
3resveratrol44 59 11 2412.0CYP1B1, TYR
4cycloheximide448.7MYOC, TYR, CYP1B1
5arginine448.6PAX6, TYR, MYOC
6dexamethasone44 49 28 1111.5CYP1B1, TYR, MYOC, OPTN

GO Terms for genes affiliated with Glaucoma, Congenital

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16Gene Ontology
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Biological processes related to Glaucoma, Congenital according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1eye developmentGO:0016549.2PAX6, FOXC1
2lacrimal gland developmentGO:0328089.1PAX6, FOXC1
3visual perceptionGO:0076018.2PAX6, CYP1B1, TYR

Molecular functions related to Glaucoma, Congenital according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1double-stranded DNA bindingGO:0036909.2PAX6, FOXC1

Products for genes affiliated with Glaucoma, Congenital

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Glaucoma, Congenital

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet