MCID: GLM006
MIFTS: 37

Glomangioma

Categories: Genetic diseases, Cancer diseases

Aliases & Classifications for Glomangioma

MalaCards integrated aliases for Glomangioma:

Name: Glomangioma 12 51 14 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2436
MeSH 41 D005918
NCIt 46 C4222
SNOMED-CT 64 7429002
UMLS 69 C0334421

Summaries for Glomangioma

MalaCards based summary : Glomangioma is related to familial glomangioma and glomus tumor, and has symptoms including pain An important gene associated with Glomangioma is GLMN (Glomulin, FKBP Associated Protein), and among its related pathways/superpathways are Cytoskeletal Signaling and HIF-1 signaling pathway. Affiliated tissues include lung, liver and trachea, and related phenotypes are cardiovascular system and behavior/neurological

Related Diseases for Glomangioma

Diseases in the Glomangioma family:

Familial Glomangioma

Diseases related to Glomangioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 158)
# Related Disease Score Top Affiliating Genes
1 familial glomangioma 33.9 FGF2 GLMN
2 glomus tumor 30.9 ACTC1 DES ENO2 VIM
3 glomangiomyoma 29.9 ACTC1 CD34 VIM
4 gastrointestinal stromal tumor 29.1 ACTC1 CD34 DES ENO2 S100A1 VIM
5 hemangioma 28.3 ACTC1 CD34 FGF2 PDPN SLC2A1 TEK
6 skin glomangioma 12.1
7 telangiectatic glomangioma 12.1
8 glomuvenous malformations 11.8
9 skin glomus tumor 10.6 DES VIM
10 lymphangiectasis 10.6 ACTC1 VIM
11 infantile digital fibromatosis 10.6 DES VIM
12 human venous malformation 10.6 GLMN TEK
13 lymphangiomatosis 10.6 DES VIM
14 ovarian fibrothecoma 10.6 ACTC1 DES
15 fibroblastic rheumatism 10.6 ACTC1 DES
16 breast rhabdomyosarcoma 10.6 DES MB
17 intravascular papillary endothelial hyperplasia 10.6 ACTC1 VIM
18 giant cell myocarditis 10.5 DES MB
19 angiolipoma 10.5 ACTC1 DES VIM
20 cutaneous leiomyosarcoma 10.5 ACTC1 DES VIM
21 spindle cell lipoma 10.5 ACTC1 DES VIM
22 parachordoma 10.5 ACTC1 DES VIM
23 syringocystadenoma papilliferum 10.5 ACTC1 DES VIM
24 benign metastasizing leiomyoma 10.5 ACTC1 DES VIM
25 congenital fibrosarcoma 10.5 ACTC1 DES VIM
26 pleomorphic liposarcoma 10.5 ACTC1 DES VIM
27 malignant triton tumor 10.5 DES MB
28 perivascular epithelioid cell tumor 10.5 ACTC1 DES VIM
29 cutaneous fibrous histiocytoma 10.5 ACTC1 DES VIM
30 spindle cell sarcoma 10.5 ACTC1 DES VIM
31 pseudosarcomatous fibromatosis 10.5 ACTC1 DES VIM
32 smooth muscle tumor 10.5 ACTC1 DES VIM
33 eosinophilic variant of chromophobe renal cell carcinoma 10.5 S100A1 SLC2A1
34 malignant fibroxanthoma 10.5 ACTC1 DES VIM
35 fasciitis 10.5 ACTC1 DES VIM
36 fibromatosis 10.5 ACTC1 DES VIM
37 bednar tumor 10.5 ENO2 VIM
38 polymorphous low-grade adenocarcinoma 10.5 ACTC1 S100A1 VIM
39 scleromyxedema 10.5 ACTC1 FGF2
40 fibrous histiocytoma 10.5 ACTC1 DES VIM
41 mesenchymoma 10.4 DES MB
42 myoepithelioma 10.4 ACTC1 S100A1 VIM
43 mongolian spot 10.4 ENO2 FLNA
44 histiocytoid hemangioma 10.4 GLMN HBA1
45 inflammatory myofibroblastic tumor 10.4 ACTC1 DES VIM
46 primitive neuroectodermal tumor of the cervix uteri 10.4 DES ENO2 VIM
47 choriocarcinoma of ovary 10.4 ENO2 TEK
48 epulis 10.4 DES ENO2 VIM
49 ectomesenchymoma 10.4 DES ENO2
50 papillary tumor of the pineal region 10.4 ENO2 S100A1 VIM

Graphical network of the top 20 diseases related to Glomangioma:



Diseases related to Glomangioma

Symptoms & Phenotypes for Glomangioma

UMLS symptoms related to Glomangioma:


pain

MGI Mouse Phenotypes related to Glomangioma:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 10.17 GLMN CD44 MB DES PDPN S100A1
2 behavior/neurological MP:0005386 10.11 FLNA CD44 DES PDPN ENO2 S100A1
3 cellular MP:0005384 10.07 FLNA ACTC1 CD34 GLMN CD44 MB
4 homeostasis/metabolism MP:0005376 10.03 ACTC1 CD34 GLMN CD44 MB DES
5 muscle MP:0005369 9.61 ACTC1 CD44 MB PDPN DES S100A1
6 respiratory system MP:0005388 9.23 FLNA CD44 MB PDPN ENO2 S100A1

Drugs & Therapeutics for Glomangioma

Search Clinical Trials , NIH Clinical Center for Glomangioma

Genetic Tests for Glomangioma

Anatomical Context for Glomangioma

MalaCards organs/tissues related to Glomangioma:

38
Lung, Liver, Trachea, Kidney

Publications for Glomangioma

Articles related to Glomangioma:

(show top 50) (show all 105)
# Title Authors Year
1
Congenital plaque-like glomangioma: report of two cases. ( 29267443 )
2017
2
Glomangioma of the Kidney: A Rare Case of Glomus Tumor and Review of the Literature. ( 28698815 )
2017
3
Gastric glomangioma, differential diagnosis of gastrointestinal stromal tumors. ( 28392052 )
2017
4
Anterior Skull Base Glomangioma-Induced Osteomalacia. ( 28180054 )
2017
5
Brace yourself: an unusual case of knee pain, an extradigital glomangioma of the knee. ( 28491188 )
2017
6
Glomangioma of the male breast. ( 28585744 )
2017
7
Large prepatellar glomangioma: A case report. ( 26254119 )
2015
8
Glomangioma of the trachea: A case report and literature review. ( 25663896 )
2015
9
Type 2 segmental glomangioma - Case report. ( 26312686 )
2015
10
Laparoscopic resection of a gastric glomangioma. ( 24639365 )
2014
11
Coexistence of glomangioma and yolk sac tumour in a child: a case report. ( 24995227 )
2014
12
Multifocal glomangioma of the gallbladder. ( 25105372 )
2014
13
Knee glomangioma: a rare location for a glomus tumor. ( 25568752 )
2014
14
Glomangioma of the lung: a case report and review of the literature. ( 24386948 )
2014
15
Paravertebral glomangioma mimicking a schwannoma. ( 24367799 )
2013
16
Large plaque-like glomangioma in a patient with multiple glomus tumours: review of imaging and histology. ( 24073652 )
2013
17
Glomangioma of the nasal septum: a case report and review. ( 23599117 )
2013
18
Solitary glomangioma mimicking a venous lake at an unusual site. ( 24164160 )
2013
19
Acquired telangiectatic plaque-like glomangioma on the forehead. ( 23679879 )
2013
20
Congenital plaque-like glomangioma treated successfully with dual wavelength pulsed-dye and neodymium:yttrium-aluminum-garnet laser. ( 23815354 )
2013
21
Atypical venous glomangioma causing chronic compression of the radial sensory nerve in the forearm. A case report and review of the literature. ( 22407591 )
2012
22
Glomangioma ("true" glomus tumor) presenting as a white middle ear mass behind an intact tympanic membrane. ( 22377651 )
2012
23
Left ventricular glomangioma. ( 22360950 )
2012
24
Orbital glomangioma. ( 22642677 )
2012
25
Congenital glomangioma of the breast: type 2 segmental manifestation. ( 21342169 )
2011
26
Primary pulmonary glomangioma: a coin lesion negative on PET study. Case report and literature review. ( 21432758 )
2011
27
Glomuvenous Malformations (Familial generalized multiple glomangiomas). ( 22031635 )
2011
28
Sellar glomangioma. ( 21912963 )
2011
29
Symplastic glomangioma: information review and addition of a new case. ( 19448066 )
2011
30
Glomangioma: a case presentation. ( 20006179 )
2010
31
Type 2 segmental glomangiomas. ( 20137750 )
2010
32
Tracheal glomangioma in a patient with asthma and chest pain. ( 19858390 )
2010
33
Extra digital glomangioma. ( 21430901 )
2010
34
Glomangioma. ( 21163162 )
2010
35
Congenital plaque-like glomangioma of the scalp. ( 19542936 )
2009
36
Glomangioma: a case report and review of the literature. ( 19271567 )
2009
37
Glomus tumor and glomangioma of the nerve. Report of two cases. ( 18240933 )
2008
38
Congenital plaque-like glomangioma associated with superficial hypertrichosis. ( 18489057 )
2008
39
Glomangioma of the nasal cavity. ( 18479616 )
2008
40
Glomangioma as a rare cause of knee pain. A report of two cases. ( 18978420 )
2008
41
Gastric multicentric glomangioma: a case report of this rare cause of abdominal pain. ( 18160947 )
2008
42
Mediastinal glomangioma: CT and octreotide scintigraphy appearance, and review of the literature. ( 19204477 )
2008
43
Granuloma annulare-like congenital multiple glomangiomas. ( 17567333 )
2007
44
[Glomulin mutations in glomuvenous malformation (glomangioma)]. ( 17384560 )
2007
45
Glomangioma of the lungs: a rare differential diagnosis of a pulmonary tumour. ( 16935981 )
2006
46
The glomangioma in the differential diagnosis of vascular malformations. ( 16998340 )
2006
47
Images in pathology. Glomangioma of the sural nerve. ( 17041200 )
2006
48
Primary glomangioma of the esophagus mimicking esophageal papilloma. ( 16723001 )
2006
49
Glomangioma in the prepuce of a dog. ( 17107519 )
2006
50
Large plaque-like glomuvenous malformation (glomangioma) simulating venous malformation. ( 16716158 )
2006

Variations for Glomangioma

Expression for Glomangioma

Search GEO for disease gene expression data for Glomangioma.

Pathways for Glomangioma

GO Terms for Glomangioma

Cellular components related to Glomangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 focal adhesion GO:0005925 9.65 ACTC1 CD44 FLNA TEK VIM
2 actin filament GO:0005884 9.5 ACTC1 FLNA TEK
3 cell-cell junction GO:0005911 9.46 DES FLNA SLC2A1 TEK
4 apical plasma membrane GO:0016324 9.35 CD34 CD44 PDPN SLC2A1 TEK
5 Z disc GO:0030018 8.92 DES FLNA S100A1 SLC2A1
6 extracellular exosome GO:0070062 10.07 ACTC1 CD44 DES ENO2 FLNA HBA1

Biological processes related to Glomangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 negative regulation of apoptotic process GO:0043066 9.8 ACTC1 CD44 FLNA PDPN TEK
2 positive regulation of ERK1 and ERK2 cascade GO:0070374 9.62 CD44 FGF2 FGF23 TEK
3 endothelial cell proliferation GO:0001935 9.48 CD34 TEK
4 hyaluronan catabolic process GO:0030214 9.46 CD44 FGF2
5 oxygen transport GO:0015671 9.43 HBA1 MB
6 stem cell proliferation GO:0072089 9.37 CD34 FGF2
7 muscle filament sliding GO:0030049 9.33 ACTC1 DES VIM
8 actin-mediated cell contraction GO:0070252 9.26 ACTC1 PDPN
9 regulation of lamellipodium morphogenesis GO:2000392 8.96 CD44 PDPN
10 wound healing, spreading of cells GO:0044319 8.8 CD44 FLNA PDPN

Molecular functions related to Glomangioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxygen carrier activity GO:0005344 8.62 HBA1 MB

Sources for Glomangioma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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