MCID: GLM007
MIFTS: 59

Glomerulonephritis malady

Categories: Rare diseases, Nephrological diseases

Aliases & Classifications for Glomerulonephritis

Aliases & Descriptions for Glomerulonephritis:

Name: Glomerulonephritis 38 12 50 52 42 14 69
Bright's Disease 50

Classifications:



External Ids:

Disease Ontology 12 DOID:2921
ICD10 33 N05 N08
MeSH 42 D005921
NCIt 47 C26784
SNOMED-CT 64 197648001 36171008
UMLS 69 C0017658

Summaries for Glomerulonephritis

NIH Rare Diseases : 50 glomerulonephritis is a type of kidney disease in which there is inflammation of the glomeruli, the tiny filters that remove excess waste and fluids from the blood. it may be acute or chronic (coming on gradually), and may occur on its own (primary) or be caused by another condition (secondary). signs and symptoms may depend on the type and cause of the condition and may include blood in the urine; foamy urine; swelling of the face, eyes, or other body parts; abdominal pain; high blood pressure; fatigue; and/or other symptoms. if the condition is severe or prolonged, the kidneys can become damaged. it may be caused by a variety of infections and diseases, and sometimes the cause is unknown. treatment depends on the cause, type and severity of the condition. last updated: 7/17/2012

MalaCards based summary : Glomerulonephritis, also known as bright's disease, is related to membranoproliferative glomerulonephritis and mesangial proliferative glomerulonephritis. An important gene associated with Glomerulonephritis is MPO (Myeloperoxidase), and among its related pathways/superpathways are Innate Immune System and Allograft rejection. The drugs Cyclosporine and Tacrolimus have been mentioned in the context of this disorder. Affiliated tissues include Kidney, kidney and neutrophil, and related phenotypes are homeostasis/metabolism and cardiovascular system

Disease Ontology : 12 A nephritis that causes inflammation of the glomeruli located in kidney.

Wikipedia : 71 Glomerulonephritis (GN), also known as glomerular nephritis, is a term used to refer to several kidney... more...

Related Diseases for Glomerulonephritis

Diseases in the Glomerulonephritis family:

Subacute Glomerulonephritis

Diseases related to Glomerulonephritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 590)
id Related Disease Score Top Affiliating Genes
1 membranoproliferative glomerulonephritis 33.9 ALB CD40LG CD79A PRTN3
2 mesangial proliferative glomerulonephritis 33.8 CD40LG CD79A
3 immune-complex glomerulonephritis 33.3 C3 CCL2 CD79A CR1 MPO
4 subacute glomerulonephritis 33.1 CD79A ICAM1 MPO PRTN3 TGFB1
5 pauci-immune glomerulonephritis 33.1 NPHS1 NPHS2
6 henoch-schoenlein purpura 32.0 ALB ICAM1 TGFB1
7 tuberculosis 30.2 CCL2 CD40LG IL1B
8 rheumatoid arthritis 29.9 CCL2 CD40LG CD79A ICAM1 IL1B PRTN3
9 filariasis 29.6 C3 CD79A MPO PRTN3
10 urticaria 29.6 ALB IL1B MPO
11 choroiditis 29.5 ALB CCL2 IL1B
12 dysentery 29.5 CD40LG CD79A MPO
13 aphthous stomatitis 29.4 ALB NPHS1 NPHS2 TGFB1
14 acute proliferative glomerulonephritis 12.2
15 rapidly progressive glomerulonephritis 12.2
16 fibrillary glomerulonephritis 12.2
17 iga glomerulonephritis 12.2
18 proliferative glomerulonephritis 12.0
19 crescentic glomerulonephritis 11.9
20 acute poststreptococcal glomerulonephritis 11.9
21 membranous nephropathy 11.9
22 diffuse glomerulonephritis 11.9
23 pauci-immune glomerulonephritis without anca 11.9
24 exudative glomerulonephritis 11.8
25 dense deposit disease/membranoproliferative glomerulonephritis type ii 11.8
26 pauci-immune glomerulonephritis with anca 11.8
27 non-immunoglobulin-mediated membranoproliferative glomerulonephritis 11.8
28 dense deposit disease 11.8
29 chronic rapidly progressive glomerulonephritis 11.7
30 goodpasture syndrome 11.7
31 marfanoid habitus with microcephaly and glomerulonephritis 11.7
32 anti-basement membrane glomerulonephritis 11.7
33 cfhr5-related dense deposit disease / membranoproliferative glomerulonephritis type ii 11.7
34 focal embolic glomerulonephritis 11.7
35 immunotactoid glomerulopathy 11.7
36 nephrotic syndrome, type 7 11.6
37 complement factor h deficiency 11.6
38 cfh-related dense deposit disease / membranoproliferative glomerulonephritis type ii 11.6
39 immunotactoid or fibrillary glomerulopathy 11.5
40 charcot-marie-tooth disease, dominant intermediate e 11.4
41 iga nephropathy 1 11.3
42 c3 glomerulopathy 11.3
43 c1q deficiency 11.3
44 wegener granulomatosis 11.2
45 alport syndrome 11.2
46 lipoid nephrosis 11.2
47 c3 deficiency 11.1
48 systemic lupus erythematosus 11.1
49 cryoglobulinemia 11.1
50 hypotrichosis-lymphedema-telangiectasia-renal defect syndrome 11.0

Graphical network of the top 20 diseases related to Glomerulonephritis:



Diseases related to Glomerulonephritis

Symptoms & Phenotypes for Glomerulonephritis

MGI Mouse Phenotypes related to Glomerulonephritis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.13 VCAM1 ALB C3 CD40LG CD79A CFI
2 cardiovascular system MP:0005385 10.11 C3 CD40LG CFP COL4A3 ICAM1 IL1B
3 hematopoietic system MP:0005397 10.1 LRP2 MPO PRTN3 TGFB1 VCAM1 CFI
4 immune system MP:0005387 9.97 C3 CCL2 CD40LG CD79A CFP COL4A3
5 mortality/aging MP:0010768 9.77 ALB C3 CD40LG CFP COL4A3 ICAM1
6 renal/urinary system MP:0005367 9.32 ALB C3 CD40LG CD79A CFI COL4A3

Drugs & Therapeutics for Glomerulonephritis

Drugs for Glomerulonephritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 251)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cyclosporine Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 79217-60-0, 59865-13-3 5284373 6435893
2
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
3
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 50-18-0, 6055-19-2 2907
4
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
5
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
6
Losartan Approved Phase 4,Phase 3,Phase 2 114798-26-4 3961
7
Candesartan Approved Phase 4 139481-59-7 2541
8
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 174722-31-7 10201696
9
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 50-24-8 5755
10
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
11
Cilnidipine Approved Phase 4 132203-70-4 5282138
12
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 83-43-2 6741
13
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
14
Probucol Approved Phase 4 23288-49-5 4912
15
Enalapril Approved, Vet_approved Phase 4,Phase 2 75847-73-3 5362032 40466924
16
Ramipril Approved Phase 4,Phase 3 87333-19-5 5362129
17
Enalaprilat Approved Phase 4,Phase 2 76420-72-9 6917719
18
Valsartan Approved, Investigational Phase 4 137862-53-4 60846
19
Azathioprine Approved Phase 4,Phase 3,Phase 2,Phase 1 446-86-6 2265
20
Hydroxychloroquine Approved Phase 4 118-42-3 3652
21
Triamcinolone Approved, Vet_approved Phase 4,Phase 1 124-94-7 31307
22
Benzocaine Approved Phase 4,Phase 3 1994-09-7, 94-09-7 2337
23
Bortezomib Approved, Investigational Phase 4 179324-69-7 387447 93860
24
Basiliximab Approved, Investigational Phase 4,Phase 2 152923-56-3, 179045-86-4
25
Entecavir Approved, Investigational Phase 4 142217-69-4 153941
26
Calcitriol Approved, Nutraceutical Phase 4,Phase 2 32222-06-3 134070 5280453
27 tannic acid Approved, Nutraceutical Phase 4,Phase 3
28
Ergocalciferol Approved, Nutraceutical Phase 4,Phase 3 50-14-6 5280793
29
N,N-dimethylarginine Experimental Phase 4 30315-93-6 123831
30
Angiotensin II Phase 4,Phase 2,Phase 3 68521-88-0, 11128-99-7 65143 172198
31 Prednisolone acetate Phase 4,Phase 2,Phase 3
32 beta-endorphin Phase 4,Phase 2,Phase 3,Phase 1
33
Candesartan cilexetil Phase 4 145040-37-5 2540
34 calcium channel blockers Phase 4
35 Alkylating Agents Phase 4,Phase 2,Phase 3,Phase 1
36 glucocorticoids Phase 4,Phase 2,Phase 3,Phase 1
37
protease inhibitors Phase 4,Phase 3,Phase 2,Phase 1
38 Mitogens Phase 4,Phase 2
39 Adrenergic Agents Phase 4,Phase 3
40 Adrenergic Antagonists Phase 4,Phase 3
41 Gastrointestinal Agents Phase 4,Phase 2,Phase 3
42 Neuroprotective Agents Phase 4,Phase 2,Phase 3
43 Adrenergic alpha-Antagonists Phase 4
44 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1
45 Adrenocorticotropic Hormone Phase 4,Phase 2,Phase 3,Phase 1
46 HIV Protease Inhibitors Phase 4,Phase 3,Phase 2,Phase 1
47 Dermatologic Agents Phase 4,Phase 3,Phase 2
48 Trace Elements Phase 4,Phase 3,Phase 2
49 Hormone Antagonists Phase 4,Phase 2,Phase 3,Phase 1
50 Hormones Phase 4,Phase 2,Phase 3,Phase 1

Interventional clinical trials:

(show top 50) (show all 307)
id Name Status NCT ID Phase
1 Efficacy and Safety of Shenyankangfu Tablets for Primary Glomerulonephritis Unknown status NCT02063100 Phase 4
2 Calcitriol in the Treatment of Immunoglobulin A Nephropathy Unknown status NCT00862693 Phase 4
3 A Prospective Study of the Kidney Protective Effect of Aliskiren in Hypertensive Patients With IgA Nephropathy Unknown status NCT01184599 Phase 4
4 CCB Safety Study in Treatment of Hypertension of ADPKD Unknown status NCT00541853 Phase 4
5 Inhibitors of Angiotensin II in Proteinuric Mesangioproliferative Glomerulonephritis Completed NCT01115426 Phase 4
6 HSP-glomerulonephritis Trial: MP vs CyA Completed NCT00425724 Phase 4
7 Long-Acting Tacrolimus for the Treatment of Resistant Lupus Nephritis Completed NCT01206569 Phase 4
8 Calcitriol in the Treatment of Immunoglobulin A (IgA) Nephropathy Completed NCT00319761 Phase 4
9 A Study of the Antioxidant Probucol Combined With Valsartan in Patients With IgA Nephropathy Completed NCT00426348 Phase 4
10 Hydroxychloroquine Sulfate for Reduction of Proteinuria in Patients With IgA Nephropathy: a Self- Controlled Study Completed NCT02351752 Phase 4
11 Mycophenolate Mofetil for IgA Nephropathy Completed NCT00863252 Phase 4
12 Comparing the Efficacy of Tacrolimus and Mycophenolate Mofetil for the Initial Therapy of Active Lupus Nephritis Completed NCT00371319 Phase 4
13 Tacrolimus for the Treatment of Systemic Lupus Erythematosus With Membranous Nephritis Completed NCT00125307 Phase 4
14 Aliskiren for Proteinuric IgAN Despite Angiotensin Blockade Completed NCT00922311 Phase 4
15 "Steroids and Azathioprine Versus Steroids Alone in IgAN" Completed NCT00755859 Phase 4
16 Rituximab in Progressive Immunoglobulin A (IgA) Nephropathy Completed NCT00498368 Phase 4
17 To Compare the Efficacy and Safety of Tripterygium Wilfordii (TW) Versus Valsartan in the Membranous Nephropathy (MN) Completed NCT00518219 Phase 4
18 Low-dose Combination of Mycophenolate Mofetil (MMF) and Tacrolimus (Tac) for Refractory Lupus Nephritis Completed NCT01203709 Phase 4
19 Inhibition of the Renin Angiotensin System Plus Corticosteroids for the Treatment of Proteinuria in IGA Nephropathy Completed NCT00367562 Phase 4
20 Acthar for Treatment of Proteinuria in Membranous Nephropathy Patients Completed NCT01386554 Phase 4
21 Idiopathic Focal Segmental Glomerulosclerosis (FSGS) and Treatment With ACTH Completed NCT01155141 Phase 4
22 Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis Completed NCT02645565 Phase 4
23 Tacrolimus Combined With Entecavir on HBV Associated Glomerulonephritis(HBV-GN) Recruiting NCT03062813 Phase 4
24 ACTHAR GEL in Patients With Membranous (Class V) Lupus Nephritis Recruiting NCT01926054 Phase 4
25 Hydroxychloroquine Sulfate Alleviates Persistent Proteinuria in IgA Nephropathy Recruiting NCT02765594 Phase 4
26 Treating to Reduce Albuminuria and Normalize Hemodynamic Function in Focal ScLerosis With dApagliflozin Trial Effects Recruiting NCT02585804 Phase 4
27 Efficacy and Safety of a Combination of Mycophenolate Mofetil and Corticosteroid in Advanced IgA Nephropathy Recruiting NCT02981212 Phase 4
28 Rituximab in Recurrent IgA Nephropathy Recruiting NCT02571842 Phase 4
29 Efficacy and Safety of Abelmoschus Manihot for IgA Nephropathy Recruiting NCT02231125 Phase 4
30 Mycophenolate Mofetil Plus Steroid in the Treatment Of Patients With Progressive Idiopathic Membranous Nephropathy Recruiting NCT03170323 Phase 4
31 Pilot Study of Velcade® in IgA Nephropathy Recruiting NCT01103778 Phase 4
32 Efficacy and Safety of Tacrolimus Versus Mycophenolate in Lupus Nephritis Recruiting NCT02630628 Phase 4
33 ACTHar in the Treatment of Lupus Nephritis Recruiting NCT02226341 Phase 4
34 Treatment of Proteinuria Due to Treatment Resistant or Treatment Intolerant Idiopathic FSGS Recruiting NCT02633046 Phase 4
35 Mycophenolate Mofetil and Tacrolimus Versus Tacrolimus for the Treatment of Idiopathic Membranous Glomerulonephritis (IMG) Active, not recruiting NCT00843856 Phase 4
36 Prevention in Recipients With Primary IgA Nephropathy of Recurrence After Kidney Transplantation: ATG-F Versus Basiliximab as Induction Immunosuppressive Treatment Active, not recruiting NCT02523768 Phase 4
37 A Study to Evaluate the Effect of Tacrolimus and Corticosteroid Combination Therapy in Patients With Minimal Change Nephrotic Syndrome Active, not recruiting NCT01763580 Phase 4
38 Treatment of Prednisone Plus Cyclophosphamide in Patients With Advanced-stage IgA Nephropathy Active, not recruiting NCT01758120 Phase 4
39 Immunoadsorption in Anti-GBM Glomerulonephritis. Not yet recruiting NCT02765789 Phase 4
40 Adrenocorticotropic Hormone in Membranous Nephropathy Not yet recruiting NCT03025828 Phase 4
41 Aldosterone Breakthrough During Diovan, Tekturna, and Combination Therapy in Patients With Proteinuric Kidney Disease Terminated NCT01129557 Phase 4
42 A Study to Evaluate the Efficacy and Safety of Tacrolimus With Steroid in Korean Lupus Nephritis Patients Terminated NCT01316133 Phase 4
43 The Efficacy and Safety of Calcitriol for the Treatment of Lupus Nephritis and Persistent Proteinuria Withdrawn NCT00508898 Phase 4
44 Acthar on Proteinuria in IgA Nephropathy Patients Withdrawn NCT02382523 Phase 4
45 Velcade for Proliferative Lupus Nephritis Withdrawn NCT01169857 Phase 4
46 Treatment of IgAN With Multi-glycoside of Tripterygium Wilfordii HOOK. f. Unknown status NCT02187900 Phase 3
47 ACTHAR GEL for Sarcoidosis-Associated Calcium Dysregulation: An Open-label Pilot Study Unknown status NCT02155803 Phase 2, Phase 3
48 RING - Rituximab for Lupus Nephritis With Remission as a Goal Unknown status NCT01673295 Phase 3
49 Efficacy and Safety of Tripterygium Wilfordii in Patients With Lupus Nephritis Unknown status NCT01646736 Phase 2, Phase 3
50 Treatment of Immunoglobulin A (IgA) Nephropathy by Angiotensin-Converting Enzyme (ACE) Inhibitor Completed NCT00437463 Phase 3

Search NIH Clinical Center for Glomerulonephritis

Cell-based therapeutics:


LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database
Read about Glomerulonephritis cell therapies at LifeMap Discovery.
Stem-cell-based therapeutic approaches for Glomerulonephritis:
Mesenchymal stromal cells for glomerulonephritis
Embryonic/Adult Cultured Cells Related to Glomerulonephritis:
Bone marrow-derived mesenchymal stromal cells PMIDs: 22172807

Cochrane evidence based reviews: glomerulonephritis

Genetic Tests for Glomerulonephritis

Anatomical Context for Glomerulonephritis

MalaCards organs/tissues related to Glomerulonephritis:

39
Kidney, Neutrophil, T Cells, Eye, Endothelial, Liver, Monocytes

The Foundational Model of Anatomy Ontology organs/tissues related to Glomerulonephritis:

18
Kidney
LifeMap Discovery
Data from LifeMap, the Embryonic Development and Stem Cells Database

Cells/anatomical compartments in embryo or adult related to Glomerulonephritis:
id Tissue Anatomical CompartmentCell Relevance
1 Kidney Glomerulus Affected by disease

Publications for Glomerulonephritis

Articles related to Glomerulonephritis:

(show top 50) (show all 3871)
id Title Authors Year
1
A rare case of concurrent myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)-associated necrotising and crescentic glomerulonephritis and membranous glomerulonephritis. ( 27931720 )
2017
2
Nitric oxide mediates prolyl hydroxylase 3 expression in mesangial cells and in glomerulonephritis. ( 28054119 )
2017
3
Association of membranoproliferative glomerulonephritis with renal cell carcinoma. ( 28004485 )
2017
4
Panitumumab-Induced Immune Complex Glomerulonephritis. ( 27765383 )
2017
5
Hepatitis B reactivation in HBsAg-negative/HBcAb-positive patients receiving immunosuppressive therapy for glomerulonephritis: a retrospective analysis. ( 28032257 )
2016
6
Formation of tight junctions between neighboring podocytes is an early ultrastructural feature in experimental crescentic glomerulonephritis. ( 27920570 )
2016
7
Granulomatosis with Polyangiitis Presenting as Pauci-Immune Crescentic Glomerulonephritis in Pregnancy. ( 27293925 )
2016
8
Complement and the kidney in the setting of Shiga-toxin hemolytic uremic syndrome, organ transplantation, and C3 glomerulonephritis. ( 27156109 )
2016
9
Study of glomerulonephritis evolution in Castilla-La Mancha (GLOMANCHA) between 1994 and 2008. ( 27137105 )
2016
10
Bilateral renal infarction mimicking rapidly progressive glomerulonephritis. ( 26822292 )
2016
11
SjAPgren Syndrome-Related Membranous Glomerulonephritis Progressing to Membranoproliferative Glomerulonephritis. ( 27904866 )
2016
12
A Red Herring in the Green Grass: Syphilitic Membranous Glomerulonephritis. ( 27888054 )
2016
13
Mesangial proliferative glomerulonephritis in murine malaria parasite, Plasmodium chabaudi AS, infected NC mice. ( 27815652 )
2016
14
Therapeutic Blockade of Immune Complex-Mediated Glomerulonephritis by Highly Selective Inhibition of Bruton's Tyrosine Kinase. ( 27192942 )
2016
15
Microscopic polyangiitis with crescentic glomerulonephritis initially presenting as acute pancreatitis. ( 26864299 )
2016
16
Ruptured Sinus of Valsalva with Infective Endocarditis Complicated with Post-Infectious Acute Glomerulonephritis: A Rare Case Presentation. ( 27891383 )
2016
17
Crescentic glomerulonephritis in children: a single centre experience. ( 26684304 )
2016
18
Antineutrophil Cytoplasmic Antibody-associated Vasculitis Superimposed on Infection-related Glomerulonephritis Secondary to Pulmonary Mycobacterium avium Complex Infection. ( 27580547 )
2016
19
Favorable renal outcome in Japanese children with ANCA-associated pauci-immune glomerulonephritis: authors' response to comments. ( 27885417 )
2016
20
Membranoproliferative Glomerulonephritis Secondary to a Low-Grade Lymphoproliferative Disorder: A Rare Cause of Renal Dysfunction. ( 27812262 )
2016
21
Aliskiren Regulates Neonatal Fc Receptor and IgG Metabolism with Attenuation of Anti-GBM Glomerulonephritis in Mice. ( 27560625 )
2016
22
Pauci-Immune Crescentic Glomerulonephritis in Connective Tissue Disease. ( 27504208 )
2016
23
Intravascular large B-cell lymphoma: masquerade as membranoproliferative glomerulonephritis. ( 27312458 )
2016
24
De novo C3 glomerulonephritis in a renal allograft. ( 26986539 )
2016
25
Glomerular disease: MDM2 - a novel target in glomerulonephritis. ( 27140847 )
2016
26
Pauci-immune glomerulonephritis: the ANCA-negative side of the coin. ( 26820837 )
2016
27
Anti-neutrophil cytoplasmic antibody-associated pauci-immune glomerulonephritis in a patient with chronic lymphocytic leukaemia. ( 27095466 )
2016
28
Bartonella Endocarditis and Pauci-Immune Glomerulonephritis: A Case Report and Review of the Literature. ( 27885316 )
2016
29
Anti-glomerular basement membrane crescentic glomerulonephritis: A report from India and review of literature. ( 27795626 )
2016
30
Severe acute cardiotoxicity following two intravenous doses of cyclophosphamide in an adolescent treated for rapidly progressive glomerulonephritis. ( 27654474 )
2016
31
Pauci-immune crescentic glomerulonephritis without ANCA in a patient presenting with Candida parapsilosis endocarditis. ( 26897307 )
2016
32
AJKD Atlas of Renal Pathology: Pauci-immune Necrotizing Crescentic Glomerulonephritis. ( 27772637 )
2016
33
Spontaneous remission of membranous glomerulonephritis with successful fetal outcome: A case report and literature review. ( 27368022 )
2016
34
Pauci Immune crescentic glomerulonephritis in a patient with T-cell lymphoma and argyria. ( 27189346 )
2016
35
C3 glomerulonephritis and autoimmune disease: more than a fortuitous association? ( 26187133 )
2016
36
Acute tubular necrosis as a part of vancomycin induced drug rash with eosinophilia and systemic symptoms syndrome with coincident postinfectious glomerulonephritis. ( 27186222 )
2016
37
Anti-CD20 therapy and pauci-immune crescentic glomerulonephritis. ( 26786252 )
2016
38
Simultaneous occurrence of fibrillary glomerulonephritis and renal lesions in nonmalignant monoclonal IgM gammopathy. ( 26892336 )
2016
39
Hilar and para-aortic necrotizing lymphadenopathy associated with antineutrophil cytoplasmic antibody-negative pauci-immune crescentic glomerulonephritis. ( 27424701 )
2016
40
Renal outcomes and risk factors for ESRD in children with rapidly progressive glomerulonephritis. ( 27542664 )
2016
41
50 Years Ago in The Journal of Pediatrics: Hemodynamic Findings in Acute Glomerulonephritis. ( 27884267 )
2016
42
Streptococcal Infection-related Nephritis (SIRN) Manifesting Membranoproliferative Glomerulonephritis Type I. ( 26984084 )
2016
43
Anaerococcus urinomassiliensis sp. nov., isolated from a urine sample of a 17-year-old boy affected by autoimmune hepatitis and membranoproliferative glomerulonephritis. ( 27408746 )
2016
44
Intestinal Intravascular Large B-cell Lymphoma Mimicking Ulcerative Colitis with Secondary Membranoproliferative Glomerulonephritis. ( 27580553 )
2016
45
Cocaine/levamisole-induced systemic vasculitis with retiform purpura and pauci-immune glomerulonephritis. ( 27119429 )
2016
46
Cerebral venous thrombosis in a patient with acute postinfectious glomerulonephritis. ( 27194837 )
2016
47
Lupus-like Immune Complex-mediated Glomerulonephritis in Patients with Hepatitis C Virus Infection Treated with Oral, Interferon-free, Direct-acting Antiviral Therapy. ( 27990496 )
2016
48
Dual anti-neutrophil cytoplasmic antibody-related pauci-immune crescentic glomerulonephritis in a patient with SjAPgren's syndrome. ( 27384449 )
2016
49
Clinical spectrum and outcomes of crescentic glomerulonephritis: A single center experience. ( 27512296 )
2016
50
Poor renal outcomes in patients with anti-neutrophil cytoplasmic antibody-associated crescentic glomerulonephritis and normal renal function at diagnosis. ( 26742758 )
2016

Variations for Glomerulonephritis

Copy number variations for Glomerulonephritis from CNVD:

7
id CNVD ID Chromosom Start End Type Gene Symbol CNVD Disease
1 21052 1 156500000 165500000 Copy number FCGR3 Glomerulonephritis
2 21055 1 156500000 165500000 Loss FCGR3B Glomerulonephritis
3 21056 1 156500000 165500000 Low copy number FCGR3B Glomerulonephritis

Expression for Glomerulonephritis

Search GEO for disease gene expression data for Glomerulonephritis.

Pathways for Glomerulonephritis

Pathways related to Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 31)
id Super pathways Score Top Affiliating Genes
1
Show member pathways
13.93 C1QC C3 CCL2 CD40LG CD79A CFI
2
Show member pathways
12.79 C3 CD40LG ICAM1 IL1B TGFB1
3
Show member pathways
12.74 C3 CCL2 CFP ICAM1 IL1B
4 12.45 CCL2 CD40LG CD79A IL1B MPO VCAM1
5 12.19 C3 CR1 IL1B TGFB1
6
Show member pathways
12.19 C3 CD40LG CR1 IL1B TGFB1
7
Show member pathways
12.18 ALB CCL2 ICAM1 IL1B LRP2 MPO
8
Show member pathways
12.08 C1QC C3 CFI CR1
9 12.06 C1QC C3 CFI CR1
10 12.05 CCL2 ICAM1 IL1B VCAM1
11 12.03 C3 CD40LG ICAM1 VCAM1
12 11.96 CCL2 ICAM1 IL1B TGFB1
13
Show member pathways
11.96 C1QC C3 CFI CFP CR1
14 11.91 CCL2 ICAM1 IL1B VCAM1
15
Show member pathways
11.89 C1QC C3 CFP CR1
16 11.86 CCL2 ICAM1 IL1B TGFB1 VCAM1
17 11.83 CD40LG ICAM1 IL1B VCAM1
18 11.79 CCL2 ICAM1 IL1B TGFB1
19 11.7 C1QC C3 IL1B
20 11.63 CCL2 COL4A3 ICAM1 IL1B TGFB1 VCAM1
21 11.61 CCL2 IL1B TGFB1
22
Show member pathways
11.61 CD40LG ICAM1 IL1B VCAM1
23 11.59 COL4A3 CR1 NPHS1 NPHS2 TGFB1
24 11.54 C3 CR1 IL1B
25 11.51 C1QC C3 CFI ICAM1
26 11.5 CD40LG CR1 ICAM1 TGFB1 VCAM1
27 11.49 CCL2 ICAM1 IL1B
28 11.31 ICAM1 IL1B VCAM1
29 11.13 CCL2 ICAM1 IL1B
30 10.86 CCL2 CD40LG CR1 ICAM1 IL1B TGFB1
31 10.56 CCL2 ICAM1 IL1B MPO VCAM1

GO Terms for Glomerulonephritis

Cellular components related to Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.97 ALB C1QC C3 CFI CR1 ICAM1
2 extracellular region GO:0005576 9.77 ALB C1QC C3 CCL2 CD40LG CFHR5
3 external side of plasma membrane GO:0009897 9.71 CD40LG CD79A ICAM1 VCAM1
4 blood microparticle GO:0072562 9.56 ALB C1QC C3 TGFB1
5 secretory granule GO:0030141 9.54 IL1B MPO TGFB1
6 extracellular space GO:0005615 9.44 ALB C1QC C3 CCL2 CD40LG CFI
7 slit diaphragm GO:0036057 9.32 NPHS1 NPHS2

Biological processes related to Glomerulonephritis according to GeneCards Suite gene sharing:

(show all 26)
id Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.93 C3 CCL2 CD40LG IL1B TGFB1
2 regulation of immune response GO:0050776 9.88 C3 CD40LG ICAM1 VCAM1
3 aging GO:0007568 9.85 CCL2 MPO TGFB1 VCAM1
4 immune response GO:0006955 9.85 C1QC C3 CCL2 CD40LG CFP IL1B
5 response to hypoxia GO:0001666 9.83 CCL2 ICAM1 TGFB1 VCAM1
6 complement activation, classical pathway GO:0006958 9.8 C1QC C3 CFI CR1
7 cellular response to organic cyclic compound GO:0071407 9.79 CCL2 IL1B TGFB1
8 positive regulation of NF-kappaB transcription factor activity GO:0051092 9.78 CD40LG ICAM1 IL1B TGFB1
9 B cell differentiation GO:0030183 9.77 CD40LG CD79A VCAM1
10 positive regulation of T cell proliferation GO:0042102 9.75 CD40LG IL1B VCAM1
11 cellular response to dexamethasone stimulus GO:0071549 9.63 CCL2 ICAM1 TGFB1
12 negative regulation of phagocytosis GO:0050765 9.62 PRTN3 TGFB1
13 chronic inflammatory response GO:0002544 9.61 CCL2 VCAM1
14 protein kinase B signaling GO:0043491 9.61 CCL2 IL1B TGFB1
15 glomerular basement membrane development GO:0032836 9.59 COL4A3 NPHS1
16 lipopolysaccharide-mediated signaling pathway GO:0031663 9.58 CCL2 IL1B TGFB1
17 positive regulation of apoptotic cell clearance GO:2000427 9.57 C3 CCL2
18 positive regulation of cellular extravasation GO:0002693 9.56 CCL2 ICAM1
19 response to lipopolysaccharide GO:0032496 9.55 CCL2 ICAM1 IL1B MPO VCAM1
20 membrane to membrane docking GO:0022614 9.51 ICAM1 VCAM1
21 positive regulation of vascular endothelial growth factor production GO:0010575 9.5 C3 IL1B TGFB1
22 leukocyte cell-cell adhesion GO:0007159 9.43 CD40LG ICAM1 VCAM1
23 complement activation, alternative pathway GO:0006957 9.13 C3 CFHR5 CFP
24 regulation of complement activation GO:0030449 9.1 C1QC C3 CFHR5 CFI CFP CR1
25 innate immune response GO:0045087 10.03 C1QC C3 CFI CFP CR1
26 neutrophil degranulation GO:0043312 10.02 C3 CFP CR1 MPO PRTN3

Molecular functions related to Glomerulonephritis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 8.92 CCL2 CD40LG IL1B TGFB1

Sources for Glomerulonephritis

3 CDC
7 CNVD
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10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
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