MCID: GLM008
MIFTS: 46

Glomus Tumor malady

Summaries for Glomus Tumor

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Disease Ontology:8 A hemangiopericytic tumor that is a mesenchymal neoplasm composed of cells that closely resemble the modified smooth muscle cells of the normal glomus body.

MalaCards: Glomus Tumor, also known as glomus neoplasm, is related to neurofibromatosis and smooth muscle tumor. An important gene associated with Glomus Tumor is SDHAF2 (succinate dehydrogenase complex assembly factor 2), and among its related pathways are Glycolysis and gluconeogenesis (short map) and Pyruvate metabolism. The compounds dexamethasone and creatinine have been mentioned in the context of this disorder. Related mouse phenotypes are integument and muscle.

Wikipedia:64 A glomus tumor (also known as a \"solitary glomus tumor,\" \"solid glomus tumor,\" or glomangioma) is a... more...

Aliases & Classifications for Glomus Tumor

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 40NCIt, 57SNOMED-CT, 35MeSH
See all sources

Aliases & Descriptions:

glomus tumor 8 45 61
glomus neoplasm 8
glomus tumour 8


External Ids:

Disease Ontology8 DOID:2431
NCIt40 C3060
MeSH35 D005918

Related Diseases for Glomus Tumor

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Glomus Tumor via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 190)
idRelated DiseaseScoreTop Affiliating Genes
1neurofibromatosis30.6VHL, S100B, NGFR, KRAS, SDHD, SDHB
2smooth muscle tumor30.4VIM, S100B, S100A1, DES, ACTC1
3paraganglioma30.4S100B, VHL, S100A1, SYP, SDHD, SDHB
4pleomorphic adenoma30.1VIM, ACTC1, MUC1, DES, S100A1, S100B
5adenoma30.1ACTC1, KRAS, MUC1, SYP, S100A1, VHL
6merkel cell carcinoma30.0SYP
7teratoma30.0ACTC1
8glomuvenous malformation30.0GLMN, KRIT1
9carotid body tumor30.0SDHD, SDHB
10multiple endocrine neoplasia30.0SDHB, SDHD, VHL
11gastrointestinal stromal tumor30.0SDHB, ACTC1, CD34, DES, S100A1, S100B
12dermatofibrosarcoma protuberans30.0VIM, ACTC1, CD34, MUC1, DES, S100A1
13squamous cell carcinoma30.0VIM, VHL, S100A1, SYP, NGFR, MUC1
14subungual glomus tumor10.8
15glomangiosarcoma10.5
16skin glomus tumor10.4
17glomus jugulare tumors10.4
18glomangiomyoma10.3
19n syndrome10.2
20chronic pain10.2
21coats disease10.1
22reversible cerebral vasoconstriction syndrome10.1
23pacinian tumor10.0
24dermatofibrosarcoma10.0
25osteoarthritis10.0
26gastric lymphoma10.0
27familial glomangioma10.0
28priapism10.0
29spiradenoma10.0
30nodular hidradenoma10.0
31gastric leiomyosarcoma10.0
32extraskeletal chondroma10.0
33vasculitis10.0
34gardner-diamond syndrome10.0
35paragangliomas 110.0
36coccygodynia10.0
37gardner syndrome10.0
38paragangliomas 210.0
39paragangliomas 310.0
40back pain10.0
41renal oncocytoma10.0S100A1
42glomangioma10.0GLMN
43lymphangioleiomyomatosis10.0DES
44fasciitis10.0ACTC1
45infantile myofibromatosis10.0DES
46parkinson's disease10.0VIM
47osteosarcoma10.0NGFR
48adenomatoid tumor10.0VIM
49thymoma10.0NGFR
50cavernous hemangioma10.0KRIT1

Graphical network of the top 20 diseases related to Glomus Tumor:



Diseases related to glomus tumor

Clinical Features for Glomus Tumor

Drugs & Therapeutics for Glomus Tumor

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Glomus Tumor

Drug clinical trials:

Search ClinicalTrials for Glomus Tumor

Search NIH Clinical Center for Glomus Tumor

Search CenterWatch for Glomus Tumor

Genetic Tests for Glomus Tumor

Anatomical Context for Glomus Tumor

Animal Models for Glomus Tumor or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
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Publications for Glomus Tumor

Sources:
51PubMed
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Articles related to Glomus Tumor:

(show top 50)    (show all 621)
idTitleAuthorsYear
1
Stereotactic radiosurgery for the treatment of Glomus Jugulare Tumors. (24349866)
2013
2
Primary glomus tumor of the liver. (21726110)
2011
3
Gastric glomus tumor: a case report and review of the literature. (20538237)
2010
4
Diagnosis of glomus tumor by nail bed and matrix dermoscopy. (20520943)
2010
5
Gamma knife radiosurgery for the treatment of glomus jugulare tumors. (19707722)
2010
6
Bronchial glomus tumor with right upper lobe atelectasis. (20625678)
2010
7
Extradigital glomus tumor as a cause of chronic perianal pain. (19679979)
2009
8
Glomus tumor and glomangioma of the nerve. Report of two cases. (18240933)
2008
9
Surgical management of glomus tympanicum tumor. (23120373)
2007
10
Glomus tumor of forearm: a rare cause of neuralgia. (17710843)
2007
11
A case of glomus tumor in a dog. (17213705)
2006
12
Revision glomus tumor surgery. (16895784)
2006
13
Comparison of radiosurgery and conventional surgery for the treatment of glomus jugulare tumors. (15329019)
2004
14
Glomus tumor of the lateral aspect of the knee joint. (14747953)
2004
15
Glomus tumor of the duodenum: a case report. (15494870)
2004
16
Extradigital glomus tumor of the triceps tendon as a cause of elbow pain: a case report. (12934039)
2003
17
Glomus tumor as a cause of chronic low back pain: case report. (12698131)
2003
18
Surgery of Glomus Jugulare Tumors. (15912172)
2003
19
The efficacy of linear accelerator stereotactic radiosurgery in treating glomus jugulare tumors. (12779355)
2003
20
Collet-Sicard syndrome disclosing glomus tumor of the skull base. (12584419)
2003
21
Malignant glomus tumor of the lung. (14507322)
2003
22
Sonographic findings in glomus tympanicum tumor. (11981934)
2002
23
Upper extremity pain of 10 years duration caused by a glomus tumor. (10660244)
2000
24
Glomus tumor of the fat pad. (9586981)
1998
25
Malignant glomus tumor. A case report of widespread metastases in a patient with multiple glomus body hamartomas. (8554113)
1996
26
Cutaneous intraneural glomus tumor. (8600806)
1995
27
Extradigital glomus tumor as a cause of knee pain. (8248416)
1993
28
Congenital arterial anomaly in the middle ear presenting as a glomus tumor. (1487462)
1992
29
Persistent stapedial artery supplying a glomus tympanicum tumor. (2363926)
1990
30
Glomus tumor of the thigh. (2164765)
1990
31
Glomus tumor in children (description of one case). (1965643)
1990
32
Glomus tumor: forty-year followup on a patient treated with surgery and radiation. (2829101)
1988
33
Glomus tumor and multiple endocrine neoplasia. (2873548)
1986
34
Exploratory nail plate removal as a diagnostic aid in painful subungual tumors: glomus tumor, neurofibroma, and squamous cell carcinoma. (3024927)
1986
35
Glomus tumor of the lip. A case report and immunohistochemical study. (2427989)
1986
36
Subungual glomus tumor: a clinico-pathological study. (6300212)
1983
37
Thick (myosin) filaments in a glomus tumor. (6295135)
1983
38
Glomus tumor of the stomach--a case report]. (185440)
1976
39
Glomus jugulare tumors: effects of radiotherapy. (164275)
1975
40
Long-term results of therapy of glomus jugulare tumors. (4346383)
1973
41
Subungual glomus tumor. Radiological manifestations. (4322892)
1970
42
Glomus tumor (chemodectoma) of the larynx. (4284860)
1965
43
A CONTRIBUTION TO THE DIAGNOSIS OF GLOMUS JUGULARE TUMORS. (14270866)
1964
44
A CONTRIBUTION TO THE DIAGNOSIS OF GLOMUS JUGULARE TUMORS. (14201680)
1964
45
TECHNIQUE FOR REMOVAL OF GLOMUS JUGULARE TUMORS. (14090421)
1964
46
Electrodiagnosis and electromyography in two unusual clinical syndromes (glomus tumor of common peroneal nerve and vasculitis of thoracolumbar portion of the spinal cord). (14007480)
1962
47
Glomus tumor of the stomach; case report. (14359072)
1955
48
Hemangiopericytoma (glomus tumor) of the mediastinum; review of the literature and report of case. (13187186)
1954
49
Recurrent glomus tumor; angioneuromyoma; a case report. (18123657)
1949
50
Glomus tumor. (20288325)
1947

Genetic Variations for Glomus Tumor

Expression for genes affiliated with Glomus Tumor

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glomus Tumor

Search GEO for disease gene expression data for Glomus Tumor.

Pathways for genes affiliated with Glomus Tumor

Sources:
12EMD Millipore, 38NCBI BioSystems Database, 54Reactome, 4Cell Signaling Technology, 52QIAGEN
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Compounds for genes affiliated with Glomus Tumor

Sources:
45Novoseek, 50PharmGKB, 29IUPHAR, 11DrugBank, 24HMDB, 60Tocris Bioscience
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Compounds related to Glomus Tumor according to GeneCards/GeneDecks:

(show top 50)    (show all 64)
idCompoundScoreTop Affiliating Genes
1dexamethasone45 50 29 1113.4S100B, KRIT1
2creatinine4510.3SDHB, ACTC1, SYP
3UBIQUINONE-11110.2SDHB, SDHD
4fumarate45 1111.1SDHB, SDHD, VHL
5glycogen45 2411.1VHL, SYP, ACTC1, SDHB
6eosin4510.1VIM, S100B, MUC1
7forskolin45 50 1112.1NGFR, VIM
8orcein4510.1VIM, S100B, DES, ACTC1
92-methoxyethanol4510.1ACTC1, S100A1, VIM
10toluidine4510.1VIM, S100A1, DES
11acetylcholine45 50 29 11 2414.0S100A1, SYP, NGFR
12ganglioside4510.0NGFR, SYP, DES, VIM
13glutamate4510.0KRIT1, NGFR
14dbc-amp459.9VIM, S100B, SYP, NGFR
15actomyosin459.9VIM, S100A1, KRIT1, ACTC1
16gold459.9DES, SYP, MUC1, KRIT1
17glucose459.8SDHB, ACTC1, MUC1, NGFR
18choline45 11 2411.8NGFR, SYP, S100B, VIM
19imatinib45 50 1111.7S100B, DES, KRAS, ACTC1
20nmda45 2910.7VIM, SYP, NGFR, KRIT1, SDHB
21biotin45 11 2411.7ACTC1, MUC1, DES, S100A1, VIM
22dihydrotestosterone45 29 11 2412.7VIM, DES, MUC1, SMTN
23s 100459.7VIM, ACTC1, MUC1, SYP, DES, S100B
24silver459.6S100A1, DES, SYP, CD34
25actinomycin d459.6VIM, VHL, DES, MUC1, KRIT1
26catecholamine459.6VIM, S100B, SYP, NGFR, SDHD, SDHB
27ethanol45 50 11 2412.5S100B, DES, SYP, NGFR, MUC1, SDHB
28h2o2459.5VIM, DES, SYP, KRAS, KRIT1, SDHB
2912-o-tetradecanoylphorbol 13-acetate459.4VIM, DES, NGFR, MUC1, CD34
30formaldehyde45 2410.4VIM, S100B, DES, SYP, MUC1, KRIT1
31mucicarmine459.3ACTC1, MUC1, SYP, DES, S100A1, S100B
32b 723459.3VIM, S100B, S100A1, DES, SYP, MUC1
33cyclic amp45 2410.3VIM, S100B, DES, SYP, NGFR, MUC1
34reticulin459.2VIM, S100B, DES, ACTC1, CD34, MUC1
35testosterone45 60 11 2412.2VIM, S100B, DES, SYP, MUC1, KRIT1
36iron45 2410.1VIM, VHL, S100B, S100A1, DES, ACTC1
37threonine459.0S100B, DES, NGFR, MUC1, CDKN2B, KRIT1
38nitric oxide45 11 2410.9VHL, S100B, S100A1, DES, SYP, NGFR
39oxygen45 249.8VHL, S100B, DES, NGFR, MUC1, KRAS
40thymidine45 249.8S100B, DES, NGFR, MUC1, CD34
41cysteine458.7VIM, S100B, S100A1, DES, SYP, NGFR
42lipid458.7VIM, S100B, SYP, NGFR, MUC1, KRAS
43hematoxylin458.6ACTC1, CD34, MUC1, NGFR, SYP, DES
44progesterone45 60 29 11 2412.6VIM, S100B, S100A1, DES, SYP, NGFR
45serine458.5VIM, VHL, S100B, DES, SYP, NGFR
46paraffin458.3VIM, S100B, S100A1, DES, SYP, NGFR
47vegf458.2DES, S100B, VHL, VIM, SYP, NGFR
48calcium45 50 11 2411.2VHL, S100B, S100A1, DES, SYP, NGFR
49retinoic acid45 249.0VIM, S100B, S100A1, DES, SYP, NGFR
50tyrosine457.5SYP, DES, S100A1, S100B, VHL, NGFR

GO Terms for genes affiliated with Glomus Tumor

Sources:
16Gene Ontology
See all sources

Cellular components related to Glomus Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular vesicular exosomeGO:0700629.8ACTG1, ACTC1, VIM
2mitochondrial respiratory chain complex IIGO:0057499.8SDHB, SDHD

Biological processes related to Glomus Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1muscle filament slidingGO:03004910.0ACTC1, DES, VIM

Molecular functions related to Glomus Tumor according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1ubiquinone bindingGO:04803910.0SDHD, SDHB
2structural constituent of cytoskeletonGO:0052009.8ACTG1, DES, VIM
3S100 protein bindingGO:0445489.5S100A1, S100B
4identical protein bindingGO:0428029.0ACTG1, SYP, DES, S100A1, S100B, VIM
5protein bindingGO:0055157.1NGFR, DES, S100A1, S100B, VHL, VIM

Products for genes affiliated with Glomus Tumor

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Sources for Glomus Tumor

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet