MCID: GLS004
MIFTS: 31

Glossopharyngeal Neuralgia malady

Neuronal diseases category

Summaries for Glossopharyngeal Neuralgia

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42NIH Rare Diseases, 43NINDS, 32MalaCards
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NIH Rare Diseases:42 Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). it typically occurs in individuals over age 40. episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. the pain may be triggered by swallowing, speaking, laughing, chewing or coughing. the condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. the goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. some antidepressants help certain people. surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases. last updated: 1/28/2013

MalaCards: Glossopharyngeal Neuralgia, also known as glossovasopharyngeal neuralgia, is related to trigeminal neuralgia and choroiditis. An important gene associated with Glossopharyngeal Neuralgia is CRLF1 (cytokine receptor-like factor 1). Affiliated tissues include tongue, tonsil and testes.

NINDS:43 Glossopharyngeal neuralgia (GN) is a rare pain syndrome that affects the glossopharyngeal nerve (the ninth cranial nerve that lies deep within the neck)

Aliases & Classifications for Glossopharyngeal Neuralgia

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8Disease Ontology, 42NIH Rare Diseases, 43NINDS, 10DISEASES, 48Orphanet, 60UMLS, 27ICD9CM, 34MeSH, 56SNOMED-CT, 26ICD10 via Orphanet, 57SNOMED-CT via Orphanet, 61UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal diseases


Aliases & Descriptions:

glossopharyngeal neuralgia 8 42 43 10 48 60
glossovasopharyngeal neuralgia 48


External Ids:

Disease Ontology8 DOID:14423
ICD9CM27 352.1
MeSH34 D020435
SNOMED-CT56 43763009
ICD10 via Orphanet26 G52.1
SNOMED-CT via Orphanet57 43763009
UMLS via Orphanet61 C0154731

Related Diseases for Glossopharyngeal Neuralgia

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17GeneCards, 18GeneDecks
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Diseases related to Glossopharyngeal Neuralgia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 18)
idRelated DiseaseScoreTop Affiliating Genes
1trigeminal neuralgia10.8
2choroiditis10.3
3arachnoiditis10.3
4multiple sclerosis10.3
5autoimmune thyroiditis10.2
6arteriovenous malformation10.2
7cerebritis10.2
8pharyngitis10.2
9chronic laryngitis10.2
10geniculate ganglionitis10.2
11facial neuralgia10.2
12sick sinus syndrome10.2
13cervicitis10.2
14hypertension10.2
15laryngitis10.2
16squamous cell carcinoma10.2
17thyroiditis10.2
18ganglioneuroma10.0POMC, GNS

Graphical network of diseases related to Glossopharyngeal Neuralgia:



Diseases related to glossopharyngeal neuralgia

Clinical Features for Glossopharyngeal Neuralgia

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Drugs & Therapeutics for Glossopharyngeal Neuralgia

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5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Genetic Tests for Glossopharyngeal Neuralgia

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Anatomical Context for Glossopharyngeal Neuralgia

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Sources:
32MalaCards
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MalaCards organs/tissues related to Glossopharyngeal Neuralgia:

32
Tongue, Tonsil, Testes, Heart, Thyroid

Animal Models for Glossopharyngeal Neuralgia or affiliated genes

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Publications for Glossopharyngeal Neuralgia

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50PubMed
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Articles related to Glossopharyngeal Neuralgia:

(show top 50)    (show all 190)
idTitleAuthorsYear
1
Treatment Of Glossopharyngeal Neuralgia With Peripheral Glycerol Injection:Our Experience In Twenty One Older Patients. (24102955)
2013
2
An uncommonly common: Glossopharyngeal neuralgia. (23661955)
2013
3
Effectiveness and safety of Gamma Knife radiosurgery for glossopharyngeal neuralgia. (23814384)
2013
4
Glossopharyngeal neuralgia in the context of a Chiari type I malformation. (22277563)
2012
5
Diagnosis and neurosurgical treatment of glossopharyngeal neuralgia: clinical findings and 3-D visualization of neurovascular compression in 19 consecutive patients. (21567138)
2011
6
Two cases of glossopharyngeal neuralgia successfully treated with pulsed radiofrequency treatment. (22065008)
2011
7
Glossopharyngeal neuralgia. (21740116)
2011
8
Jugular foramen schwannoma presenting with glossopharyngeal neuralgia syncope syndrome. (20602849)
2010
9
MRI findings in a patient with glossopharyngeal neuralgia. (20461678)
2010
10
MRI of glossopharyngeal neuralgia caused by neurovascular compression. (18647935)
2008
11
Glossopharyngeal neuralgia with syncope as a sign of neck cancer recurrence. (18345437)
2007
12
Trigeminal and concurrent glossopharyngeal neuralgia secondary to lateral medullary infarction. (16552020)
2006
13
Oxcarbazepine in glossopharyngeal neuralgia: clinical response and effect on serum lipids. (15623731)
2004
14
Glossopharyngeal neuralgia with cardiac syncope treated by glossopharyngeal rhizotomy and microvascular decompression. (12633639)
2003
15
Cranial root injury in glossopharyngeal neuralgia: electron microscopic observations. Case report. (11883848)
2002
16
Glossopharyngeal neuralgia associated with aberrant internal carotid artery in the oropharynx. (11860076)
2002
17
Glossopharyngeal neuralgia and MS. (10746612)
2000
18
Tonsillar pain mimicking glossopharyngeal neuralgia as a complication of vagus nerve stimulation: case report. (10897165)
2000
19
Possible role of an endovascular provocative test in the diagnosis of glossopharyngeal neuralgia as a vascular compression syndrome. (10592125)
1999
20
The glossopharyngeal nerve, glossopharyngeal neuralgia and the Eagle's syndrome--current concepts and management. (10741197)
1999
21
Glossopharyngeal neuralgia associated with a vascular loop demonstrated by magnetic resonance imaging. (9810448)
1998
22
Glossopharyngeal neuralgia: a study of 6 cases. (9297722)
1997
23
Glossopharyngeal neuralgia with tongue carcinoma. (9213422)
1997
24
Outcome after microvascular decompression for typical trigeminal neuralgia, hemifacial spasm, tinnitus, disabling positional vertigo, and glossopharyngeal neuralgia (honored guest lecture). (10080016)
1997
25
Microvascular decompression in glossopharyngeal neuralgia. (8588627)
1995
26
Pain arising from the oesophagus may mimic glossopharyngeal neuralgia. (8505655)
1993
27
Glossopharyngeal neuralgia from a posterior fossa arteriovenous malformation: resolution following embolization. (8414049)
1993
28
Incidence and clinical features of glossopharyngeal neuralgia, Rochester, Minnesota, 1945-1984. (1798429)
1991
29
Glossopharyngeal neuralgia: successful treatment with baclofen. (3592645)
1987
30
Treatment of glossopharyngeal neuralgia by carbamazepine. (3663432)
1987
31
Glossopharyngeal neuralgia with cardiac syncope. A case successfully treated by microvascular decompression. (4023909)
1985
32
Glossopharyngeal neuralgia-asystole syndrome secondary to parapharyngeal space lesions. (6806751)
1982
33
Glossopharyngeal neuralgia of traumatic origin. (7071723)
1982
34
Glossopharyngeal neuralgia with syncope secondary to tumor. Treatment and pathophysiology. (7246575)
1981
35
Glossopharyngeal neuralgia due to exuberant choroid plexus. (7414478)
1980
36
Familial trigeminal and glossopharyngeal neuralgia. (550953)
1979
37
Glossopharyngeal neuralgia with syncope. (336819)
1977
38
Glossopharyngeal neuralgia as the cause of cardiac syncope. (A case report with a review of literature). (1055777)
1975
39
Glossopharyngeal neuralgia--implications for the anesthesiologist. (4652787)
1972
40
Tornwaldt's disease. Onset as symptomatic (secondary) glossopharyngeal neuralgia. (4673561)
1972
41
Trigeminal neuralgia, facial spasm, intermedius and glossopharyngeal neuralgia with persistent carotid basilar anastomosis. (5349090)
1969
42
Glossopharyngeal neuralgia with cerebral and cardiovascular symptomatology. (13960468)
1962
43
A case of glossopharyngeal neuralgia. (13913356)
1962
44
Combined trigeminal and glossopharyngeal neuralgia. (13400213)
1957
45
The surgical treatment of trigeminal and glossopharyngeal neuralgia: decompression of the Gasserian ganglion and its root for trigeminal pain. (13118219)
1954
46
Glossopharyngeal neuralgia with syncope and convulsions. (13044616)
1953
47
Glossopharyngeal neuralgia; report of two unusual cases. (12991089)
1952
48
Glossopharyngeal neuralgia; tic douloureux of the ninth cranial nerve. (15394992)
1949
49
GLOSSOPHARYNGEAL NEURALGIA. (17856446)
1935
50
A CASE OF GLOSSOPHARYNGEAL NEURALGIA. (20776085)
1931

Genetic Variations for Glossopharyngeal Neuralgia

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Expression for genes affiliated with Glossopharyngeal Neuralgia

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glossopharyngeal Neuralgia

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Pathways for genes affiliated with Glossopharyngeal Neuralgia

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Compounds for genes affiliated with Glossopharyngeal Neuralgia

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GO Terms for genes affiliated with Glossopharyngeal Neuralgia

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Products for genes affiliated with Glossopharyngeal Neuralgia

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Sources for Glossopharyngeal Neuralgia

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet