MCID: GLS004
MIFTS: 29

Glossopharyngeal Neuralgia malady

Neuronal category

Summaries for Glossopharyngeal Neuralgia

Sources:
43NIH Rare Diseases, 44NINDS, 33MalaCards
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NIH Rare Diseases:43 Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). it typically occurs in individuals over age 40. episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. the pain may be triggered by swallowing, speaking, laughing, chewing or coughing. the condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. the goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. some antidepressants help certain people. surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases. last updated: 1/28/2013

MalaCards: Glossopharyngeal Neuralgia, also known as glossovasopharyngeal neuralgia, is related to syncope and trigeminal neuralgia. An important gene associated with Glossopharyngeal Neuralgia is CRLF1 (cytokine receptor-like factor 1). Affiliated tissues include heart, thyroid and tonsil.

NINDS:44 Glossopharyngeal neuralgia (GN) is a rare pain syndrome that affects the glossopharyngeal nerve (the ninth cranial nerve that lies deep within the neck)

Aliases & Classifications for Glossopharyngeal Neuralgia

Sources:
8Disease Ontology, 43NIH Rare Diseases, 44NINDS, 10DISEASES, 49Orphanet, 61UMLS, 27ICD9CM, 35MeSH, 57SNOMED-CT, 26ICD10 via Orphanet, 58SNOMED-CT via Orphanet, 62UMLS via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Neuronal


Aliases & Descriptions:

glossopharyngeal neuralgia 8 43 44 10 49 61
glossovasopharyngeal neuralgia 49


External Ids:

Disease Ontology8 DOID:14423
ICD9CM27 352.1
MeSH35 D020435
SNOMED-CT57 43763009
ICD10 via Orphanet26 G52.1
SNOMED-CT via Orphanet58 43763009
UMLS via Orphanet62 C0154731

Related Diseases for Glossopharyngeal Neuralgia

Sources:
17GeneCards, 18GeneDecks
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Diseases related to Glossopharyngeal Neuralgia via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 15)
idRelated DiseaseScoreTop Affiliating Genes
1syncope11.0
2trigeminal neuralgia10.9
3n syndrome10.7
4hemifacial spasm10.6
5eagle syndrome10.3
6arteriovenous malformation10.2
7geniculate ganglionitis10.2
8facial neuralgia10.2
9sick sinus syndrome10.2
10squamous cell carcinoma10.2
11micro syndrome10.2
12cluster headache10.2
13chronic pain10.2
14headache10.2
15ganglioneuroma10.0POMC, GNS

Graphical network of diseases related to Glossopharyngeal Neuralgia:



Diseases related to glossopharyngeal neuralgia

Clinical Features for Glossopharyngeal Neuralgia

Drugs & Therapeutics for Glossopharyngeal Neuralgia

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Glossopharyngeal Neuralgia

Drug clinical trials:

Search ClinicalTrials for Glossopharyngeal Neuralgia

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Genetic Tests for Glossopharyngeal Neuralgia

Anatomical Context for Glossopharyngeal Neuralgia

Sources:
33MalaCards
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MalaCards organs/tissues related to Glossopharyngeal Neuralgia:

33
Heart, Thyroid, Tonsil, T cells, Trigeminal ganglion, Tongue

Animal Models for Glossopharyngeal Neuralgia or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Glossopharyngeal Neuralgia

Sources:
51PubMed
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Articles related to Glossopharyngeal Neuralgia:

(show top 50)    (show all 192)
idTitleAuthorsYear
1
Peripheral glycerol injection: An alternative treatment of children with glossopharyngeal neuralgia. (24418185)
2013
2
Giant dumbbell-shaped intra- and extracranial nerve schwannoma in a child presenting with glossopharyngeal neuralgia syncope syndrome: a case report and review of the literature. (23104590)
2013
3
Glossopharyngeal neuralgia due to ectatic anterior inferior cerebellar artery. (22954993)
2012
4
Syncopal storm caused by glossopharyngeal neuralgia. (22633719)
2012
5
Non-surgical therapy for bilateral glossopharyngeal neuralgia caused by Eagle's syndrome, diagnosed by three-dimensional computed tomography: a case report. (22760524)
2012
6
Use of endotracheal tube electrodes in treating glossopharyngeal neuralgia: technical note. (22508038)
2012
7
Diagnosis and neurosurgical treatment of glossopharyngeal neuralgia: clinical findings and 3-D visualization of neurovascular compression in 19 consecutive patients. (21567138)
2011
8
Glossopharyngeal neuralgia: a presentation of 14 cases. (21272973)
2011
9
Teaching neuroimages: glossopharyngeal neuralgia with syncope: heart rate and blood pressure change. (21968850)
2011
10
Treatment of a patient with glossopharyngeal neuralgia by the anterior tonsillar pillar method. (21468360)
2011
11
Ondine's curse with accompanying trigeminal and glossopharyngeal neuralgia secondary to medullary telangiectasia. (20066515)
2010
12
Severe pain attack associated with neurocardiogenic syncope induced by glossopharyngeal neuralgia: successful treatment with carbamazepine and a permanent pacemaker -a case report-. (20830270)
2010
13
Microvascular decompression for glossopharyngeal neuralgia through the transcondylar fossa (supracondylar transjugular tubercle) approach. (20489516)
2010
14
Microvascular decompression for glossopharyngeal neuralgia: a long-term retrospectic review of the Milan-Bologna experience in 31 consecutive cases. (19513582)
2009
15
Glossopharyngeal neuralgia: neurosurgical treatment and differential diagnosis. (18231706)
2008
16
Use of lamotrigine in glossopharyngeal neuralgia: a case report. (16412166)
2006
17
Pulsed mode radiofrequency lesioning to treat chronic post-tonsillectomy pain (secondary glossopharyngeal neuralgia). (17147673)
2003
18
Microvascular decompression for treatment of trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia: three surgical approach variations: technical note. (14633313)
2003
19
Prolonged cardiac arrest caused by glossopharyngeal neuralgia. (12639862)
2003
20
Gabapentin treatment of glossopharyngeal neuralgia: a follow-up of four years of a single case. (12160515)
2002
21
Glossopharyngeal neuralgia caused by adhesive arachnoid. (12382135)
2002
22
Follow-up results of using microvascular decompression for treatment of glossopharyngeal neuralgia. (9452227)
1998
23
Relief of glossopharyngeal neuralgia by ketamine-induced N-methyl-aspartate receptor blockade. (9257324)
1997
24
Glossopharyngeal neuralgia with cardiac syncope. (7708169)
1995
25
Glossopharyngeal neuralgia associated with cardiac syncope and weight loss. (7917215)
1994
26
Glossopharyngeal neuralgia and syncope secondary to neck malignancy. (8445696)
1993
27
Epidemiology and clinical features of idiopathic trigeminal neuralgia and glossopharyngeal neuralgia: similarities and differences, Rochester, Minnesota, 1945-1984. (1798430)
1991
28
Glossopharyngeal neuralgia associated with cardiac syncope: long term treatment with permanent pacing and carbamazepine. (2271351)
1990
29
Surgical treatment of glossopharyngeal neuralgia via the pharyngeal approach. (2179439)
1990
30
Transvenous pacing for the anesthetic management of surgery for glossopharyngeal neuralgia. (2240656)
1990
31
Glossopharyngeal neuralgia with syncope and cervical mass. (2496390)
1989
32
Intracranial microvascular decompression for "cryptogenic" hemifacial spasm, trigeminal and glossopharyngeal neuralgia, paroxysmal vertigo and tinnitus: II. Clinical study and long-term follow up. (3733417)
1986
33
Combined trigeminal and glossopharyngeal neuralgia. (4035551)
1985
34
Bradycardic and vasodepressor syncope secondary to glossopharyngeal neuralgia from hypopharyngeal tumor. (3993518)
1985
35
Glossopharyngeal neuralgia with syncope. (6842058)
1983
36
Glossopharyngeal neuralgia associated with syncope and seizures. (7070639)
1982
37
The glossopharyngeal neuralgia patient. (6899743)
1980
38
Familial trigeminal and glossopharyngeal neuralgia. (550953)
1979
39
Glossopharyngeal neuralgia with syncope. (435778)
1979
40
Cardiac syncope secondary to glossopharyngeal neuralgia--effectively treated with carbamazepine. (101534)
1978
41
Glossopharyngeal neuralgia--implications for the anesthesiologist. (4652787)
1972
42
GLOSSOPHARYNGEAL NEURALGIA ASSOCIATED WITH BRADYCARDIA, SYNCOPE, AND SEIZURES. (14197829)
1964
43
A SURGICAL TECHNIQUE FOR THE RELIEF OF GLOSSOPHARYNGEAL NEURALGIA. (14088729)
1963
44
Glossopharyngeal neuralgia and ossification of the stylohyoid ligament. (13665400)
1959
45
The surgical treatment of trigeminal and glossopharyngeal neuralgia: decompression of the Gasserian ganglion and its root for trigeminal pain. (13118219)
1954
46
The vagus nerve in surgical consideration of glossopharyngeal neuralgia. (14795251)
1950
47
Glossopharyngeal neuralgia associated with cardiac arrest and convulsions. (15400036)
1950
48
Glossopharyngeal neuralgia; extracranial neurectomy. (18895133)
1948
49
Glossopharyngeal Neuralgia treated by Trans-Tonsillar Section of the Nerve. (19993453)
1946
50
DIAGNOSIS AND TREATMENT OF GLOSSOPHARYNGEAL NEURALGIA. (17857808)
1941

Genetic Variations for Glossopharyngeal Neuralgia

Expression for genes affiliated with Glossopharyngeal Neuralgia

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glossopharyngeal Neuralgia

Search GEO for disease gene expression data for Glossopharyngeal Neuralgia.

Pathways for genes affiliated with Glossopharyngeal Neuralgia

Compounds for genes affiliated with Glossopharyngeal Neuralgia

GO Terms for genes affiliated with Glossopharyngeal Neuralgia

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Sources for Glossopharyngeal Neuralgia

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet