MCID: GLS004
MIFTS: 33

Glossopharyngeal Neuralgia malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Glossopharyngeal Neuralgia

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Sources:
11Disease Ontology, 46NIH Rare Diseases, 47NINDS, 13DISEASES, 52Orphanet, 37MeSH, 66UMLS, 28ICD10, 30ICD9CM, 29ICD10 via Orphanet, 67UMLS via Orphanet, 60SNOMED-CT
See all MalaCards sources

Aliases & Descriptions for Glossopharyngeal Neuralgia:

Name: Glossopharyngeal Neuralgia 11 46 47 13 52 66
Glossopharyngeal Nerve Diseases 37
 
Glossovasopharyngeal Neuralgia 52

Classifications:



External Ids:

Disease Ontology11 DOID:14423
ICD1028 G52.1
ICD9CM30 352.1
MeSH37 D020435
SNOMED-CT60 43763009
Orphanet52 ORPHA221098
ICD10 via Orphanet29 G52.1
UMLS via Orphanet67 C0154731

Summaries for Glossopharyngeal Neuralgia

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NIH Rare Diseases:46 Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). it typically occurs in individuals over age 40. episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. the pain may be triggered by swallowing, speaking, laughing, chewing or coughing. the condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. the goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. some antidepressants help certain people. surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases. last updated: 1/28/2013

MalaCards based summary: Glossopharyngeal Neuralgia, also known as glossopharyngeal nerve diseases, is related to glossopharyngeal nerve disease and syncope, and has symptoms including pain An important gene associated with Glossopharyngeal Neuralgia is POMC (Proopiomelanocortin). Affiliated tissues include tongue, tonsil and cortex.

NINDS:47 Glossopharyngeal neuralgia (GN) is a rare pain syndrome that affects the glossopharyngeal nerve (the ninth cranial nerve that lies deep within the neck)

Related Diseases for Glossopharyngeal Neuralgia

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Diseases related to Glossopharyngeal Neuralgia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 40)
idRelated DiseaseScoreTop Affiliating Genes
1glossopharyngeal nerve disease12.2
2syncope10.7
3trigeminal neuralgia10.5
4hemifacial spasm10.4
5gallbladder adenoma10.4POMC, VIM
6rheumatic fever10.3KANTR, POMC
7ancylostomiasis10.3KANTR, POMC
8cardiac arrest10.3
9purulent labyrinthitis10.3CRLF1, KANTR
10atopic dermatitis10.3KANTR, POMC
11olfactory neuroblastoma10.3CRLF1, KANTR
12glioma susceptibility 110.2POMC, VIM
13congenital epulis10.2KANTR, POMC
14cerebral arterial disease10.2CANX, KANTR
15chromophobe adenoma10.2KANTR, POMC
16geniculate ganglionitis10.2
17balanitis10.2CRLF1, KANTR
18obstructive sleep apnea10.1KANTR, VIM
19choroiditis10.1
20arachnoiditis10.1
21tendinopathy10.0KANTR, POMC
22peritoneal benign neoplasm10.0CRLF1, KANTR, POMC
23frontal sinus squamous cell carcinoma10.0KANTR, VIM
24lipoma9.9
25arteriovenous malformation9.9
26sick sinus syndrome9.9
27pharyngitis9.9
28cervicitis9.9
29cerebritis9.9
30laryngitis9.9
31thyroiditis9.9
32arachnoid cysts9.9
33cluster headache9.9
34headache9.9
35combined hyperactive dysfunction syndrome of the cranial nerves9.9
36anismus9.9KANTR, VIM
37adult brain stem glioma9.8KANTR, VIM
38keratoacanthoma9.8HNF4A, POMC
39subclavian artery aneurysm6.9BNIP3L, CANX, CRLF1, HNF4A, KANTR, LONP1
40cerebral degeneration6.6BNIP3L, CANX, CRLF1, HNF4A, KANTR, LONP1

Comorbidity relations with Glossopharyngeal Neuralgia via Phenotypic Disease Network (PDN):


Trigeminal Neuralgia

Graphical network of the top 20 diseases related to Glossopharyngeal Neuralgia:



Diseases related to glossopharyngeal neuralgia

Symptoms for Glossopharyngeal Neuralgia

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UMLS symptoms related to Glossopharyngeal Neuralgia:


pain

Drugs & Therapeutics for Glossopharyngeal Neuralgia

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Drugs for Glossopharyngeal Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Lidocaine1168137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bio-0767
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Cuivasil
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
DermaFlex
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gravocain
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
 
LS-805
Lanabiotic
Leostesin
Lida-Mantle
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocainum
Lidocainum [INN-Latin]
Lidocaton
Lidoderm
Lidoject-1
Lidoject-2
Lignocaine
Lignocainum
Lingocaine
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Octocaine
Octocaine-100
Octocaine-50
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-MPF
Xylocaine-MPF with Glucose
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
╬▒-diethylamino-2,6-dimethylacetanilide

Interventional clinical trials:

idNameStatusNCT IDPhase
1Interest of Pregabalin (Lyrica) on the Treatment of Reflex Earache in Head and Neck Cancer.RecruitingNCT02924675Phase 2
2Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.RecruitingNCT02321566Phase 1
3Air Stacking vs Glossopharyngeal Breathing in Neuromuscular DiseasesCompletedNCT02500030
4Glossopharyngeal Nerve Block for Awake IntubationCompletedNCT01790464

Search NIH Clinical Center for Glossopharyngeal Neuralgia


Cochrane evidence based reviews: glossopharyngeal nerve diseases

Genetic Tests for Glossopharyngeal Neuralgia

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Anatomical Context for Glossopharyngeal Neuralgia

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MalaCards organs/tissues related to Glossopharyngeal Neuralgia:

34
Tongue, Tonsil, Cortex, Testes, Heart, Trigeminal ganglion, Thyroid

Animal Models for Glossopharyngeal Neuralgia or affiliated genes

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Publications for Glossopharyngeal Neuralgia

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Articles related to Glossopharyngeal Neuralgia:

(show top 50)    (show all 213)
idTitleAuthorsYear
1
Case report: Recurrent glossopharyngeal neuralgia after previous glossopharyngeal rhizotomy: Microvascular decompression with intra-operative neurophysiology. (25958960)
2015
2
Vago-glossopharyngeal neuralgia: a literature review of neurosurgical experience. (25526720)
2015
3
Glossopharyngeal nerve contrast enhancement in recent-onset glossopharyngeal neuralgia. (25802271)
2015
4
Conventional and 3-Dimensional Computerized Tomography in Eagle's Syndrome, Glossopharyngeal Neuralgia, and Asymptomatic Controls. (25917666)
2015
5
Peripheral glycerol injection: An alternative treatment of children with glossopharyngeal neuralgia. (24418185)
2013
6
Treatment Of Glossopharyngeal Neuralgia With Peripheral Glycerol Injection:Our Experience In Twenty One Older Patients. (24102955)
2013
7
Keyhole microsurgery for trigeminal neuralgia, hemifacial spasm and glossopharyngeal neuralgia. (19536556)
2010
8
Glossopharyngeal neuralgia treated with gamma knife radiosurgery. (20849803)
2010
9
Ondine's curse with accompanying trigeminal and glossopharyngeal neuralgia secondary to medullary telangiectasia. (20066515)
2010
10
MRI of glossopharyngeal neuralgia caused by neurovascular compression. (18647935)
2008
11
Usefulness of balloon test occlusion in the diagnosis of glossopharyngeal neuralgia. Case report. (18434694)
2008
12
Glossopharyngeal neuralgia with cardiac syncope: an idiopathic case treated with carbamazepine and duloxetine. (18355311)
2008
13
Glossopharyngeal neuralgia due to vascular compression by tortuous left posterior inferior cerebellar artery: a high strength (1.5 T) MRI study. (24299939)
2007
14
Glossopharyngeal neuralgia responding to pregabalin. (16942480)
2006
15
Trigeminal and concurrent glossopharyngeal neuralgia secondary to lateral medullary infarction. (16552020)
2006
16
Glossopharyngeal neuralgia treated with gamma knife surgery: treatment outcome and failure analysis. Case report. (15662801)
2005
17
Oxcarbazepine in glossopharyngeal neuralgia: clinical response and effect on serum lipids. (15623731)
2004
18
Pulsed mode radiofrequency lesioning to treat chronic post-tonsillectomy pain (secondary glossopharyngeal neuralgia). (17147673)
2003
19
Microvascular decompression for treatment of trigeminal neuralgia, hemifacial spasm, and glossopharyngeal neuralgia: three surgical approach variations: technical note. (14633313)
2003
20
Cranial root injury in glossopharyngeal neuralgia: electron microscopic observations. Case report. (11883848)
2002
21
Glossopharyngeal neuralgia associated with aberrant internal carotid artery in the oropharynx. (11860076)
2002
22
Serotonin mediated cluster headache, trigeminal neuralgia, glossopharyngeal neuralgia, and superior laryngeal neuralgia with SAD chronicity. (11579658)
2001
23
Possible role of an endovascular provocative test in the diagnosis of glossopharyngeal neuralgia as a vascular compression syndrome. (10592125)
1999
24
The glossopharyngeal nerve, glossopharyngeal neuralgia and the Eagle's syndrome--current concepts and management. (10741197)
1999
25
Follow-up results of using microvascular decompression for treatment of glossopharyngeal neuralgia. (9452227)
1998
26
Glossopharyngeal neuralgia: a study of 6 cases. (9297722)
1997
27
Chiari type I malformation, glossopharyngeal neuralgia and central sleep apnoea in a child. (8973298)
1996
28
Glossopharyngeal neuralgia with cardiac syncope. (7708169)
1995
29
Glossopharyngeal neuralgia from a posterior fossa arteriovenous malformation: resolution following embolization. (8414049)
1993
30
Life-threatening glossopharyngeal neuralgia. (1642589)
1992
31
Surgical treatment of glossopharyngeal neuralgia via the pharyngeal approach. (2179439)
1990
32
Glossopharyngeal neuralgia: successful treatment with baclofen. (3592645)
1987
33
Percutaneous radio-frequency thermocoagulation with low temperature in the treatment of essential glossopharyngeal neuralgia. (3941978)
1986
34
Swallow syncope: a form of glossopharyngeal neuralgia? (3942939)
1986
35
Combined trigeminal and glossopharyngeal neuralgia. (4035551)
1985
36
Bradycardic and vasodepressor syncope secondary to glossopharyngeal neuralgia from hypopharyngeal tumor. (3993518)
1985
37
Glossopharyngeal neuralgia with cardiac syncope. A case successfully treated by microvascular decompression. (4023909)
1985
38
Glossopharyngeal neuralgia. (6313200)
1983
39
The glossopharyngeal neuralgia patient. (6899743)
1980
40
Glossopharyngeal neuralgia due to exuberant choroid plexus. (7414478)
1980
41
Familial trigeminal and glossopharyngeal neuralgia. (550953)
1979
42
Glossopharyngeal neuralgia: surgical treatment and electron microscopic findings. (1263728)
1976
43
Glossopharyngeal neuralgia--implications for the anesthesiologist. (4652787)
1972
44
A new approach to the treatment of glossopharyngeal neuralgia, using the great auricular nerve block. (5899883)
1965
45
Partial glossopharyngeal neuralgia associated with syncope. (13439423)
1957
46
The surgical treatment of trigeminal and glossopharyngeal neuralgia: decompression of the Gasserian ganglion and its root for trigeminal pain. (13118219)
1954
47
The vagus nerve in surgical consideration of glossopharyngeal neuralgia. (14795251)
1950
48
Glossopharyngeal neuralgia associated with cardiac arrest and convulsions. (15400036)
1950
49
DIAGNOSIS AND TREATMENT OF GLOSSOPHARYNGEAL NEURALGIA. (17857808)
1941
50
A CASE OF GLOSSOPHARYNGEAL NEURALGIA. (20776085)
1931

Variations for Glossopharyngeal Neuralgia

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Expression for genes affiliated with Glossopharyngeal Neuralgia

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Search GEO for disease gene expression data for Glossopharyngeal Neuralgia.

Pathways for genes affiliated with Glossopharyngeal Neuralgia

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GO Terms for genes affiliated with Glossopharyngeal Neuralgia

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Biological processes related to Glossopharyngeal Neuralgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1SMAD protein signal transductionGO:00603959.6HNF4A, VIM

Molecular functions related to Glossopharyngeal Neuralgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1glycoprotein bindingGO:00019489.7CANX, VIM

Sources for Glossopharyngeal Neuralgia

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet