MCID: GLS004
MIFTS: 32

Glossopharyngeal Neuralgia malady

Categories: Rare diseases, Neuronal diseases

Aliases & Classifications for Glossopharyngeal Neuralgia

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Sources:
10Disease Ontology, 45NIH Rare Diseases, 46NINDS, 12DISEASES, 51Orphanet, 36MeSH, 65UMLS, 27ICD10, 29ICD9CM, 59SNOMED-CT, 28ICD10 via Orphanet, 66UMLS via Orphanet
See all MalaCards sources

Aliases & Descriptions for Glossopharyngeal Neuralgia:

Name: Glossopharyngeal Neuralgia 10 45 46 12 51 65
Glossopharyngeal Nerve Diseases 36 65
 
Glossovasopharyngeal Neuralgia 51

Classifications:



External Ids:

Disease Ontology10 DOID:14423
ICD1027 G52.1
ICD9CM29 352.1
MeSH36 D020435
SNOMED-CT59 43763009
Orphanet51 221098
ICD10 via Orphanet28 G52.1
UMLS via Orphanet66 C0154731
UMLS65 C0154731, C0751941

Summaries for Glossopharyngeal Neuralgia

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NIH Rare Diseases:45 Glossopharyngeal neuralgia is a condition characterized by repeated episodes of severe pain in the tongue, throat, ear, and tonsils (areas connected to the ninth cranial nerve, or glossopharyngeal nerve). it typically occurs in individuals over age 40. episodes of pain may last from a few seconds to a few minutes, and usually occur on one side. the pain may be triggered by swallowing, speaking, laughing, chewing or coughing. the condition is thought to be due to irritation of the nerve, although the source of irritation is unclear. the goal of treatment is to control pain, but over-the-counter pain medications are not very effective; the most effective drugs are anti-seizure medications. some antidepressants help certain people. surgery to cut or take pressure off of the glossopharyngeal nerve may be needed in severe cases. last updated: 1/28/2013

MalaCards based summary: Glossopharyngeal Neuralgia, also known as glossopharyngeal nerve diseases, is related to glossopharyngeal nerve disease and geniculate ganglionitis. An important gene associated with Glossopharyngeal Neuralgia is POMC (Proopiomelanocortin). Affiliated tissues include tongue, tonsil and breast.

NINDS:46 Glossopharyngeal neuralgia (GN) is a rare pain syndrome that affects the glossopharyngeal nerve (the ninth cranial nerve that lies deep within the neck)

Related Diseases for Glossopharyngeal Neuralgia

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Graphical network of the top 20 diseases related to Glossopharyngeal Neuralgia:



Diseases related to glossopharyngeal neuralgia

Symptoms for Glossopharyngeal Neuralgia

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Drugs & Therapeutics for Glossopharyngeal Neuralgia

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Drugs for Glossopharyngeal Neuralgia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 8)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
Lidocaineapproved1103137-58-63676
Synonyms:
.alpha.-(Diethylamino)-2,6-acetoxylidide
.alpha.-Diethylamino-2,6-dimethylacetanilide
.alpha.-Diethylaminoaceto-2,6-xylidide
.omega.-Diethylamino-2,6-dimethylacetanilide
137-58-6
2-(Diethylamino)-2',6'-acetoxylidide
2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamide
2-Diethylamino-N-(2,6-dimethylphenyl)acetamide
4-12-00-02538 (Beilstein Handbook Reference)
6108-05-0 (MONOHYDROCHLORIDE MONOHYDRATE))
6108-05-0 (mono-hydrochloride, mono-hydrate)
73-78-9 (mono-hydrochloride)
AB00053581
AC-10282
AC1L1GGQ
AC1Q2Z7J
AKOS001026768
ARONIS23855
After Burn Double Strength Gel
After Burn Double Strength Spray
After Burn Gel
After Burn Spray
Afterburn
Akten
Alphacaine
Anestacon
Anestacon Jelly
BIDD:GT0342
BPBio1_000197
BRD-K52662033-001-02-6
BRD-K52662033-003-05-5
BRN 2215784
BSPBio_000179
BSPBio_001359
BSPBio_003004
Bikini Zone Medicated
Bikini Zone Medicated Creme
Bio-0767
Bio-scriptives Lidum
Bio-scriptives Lidum Hemorroidal (anorectal)
Bio-scriptives Lidum Topical Analgesic
Bio1_000379
Bio1_000868
Bio1_001357
Bio2_000079
Bio2_000559
Burn Relief Leader
C07073
C14H22N2O
CAS-73-78-9
CDS1_000283
CHEBI:6456
CHEMBL79
CID3676
CPD000058189
Cappicaine
Cito optadren
Comfortcaine
Cuivasil
Curacaine Transdermal Corporation
D00358
DB00281
Dalcaine
Dentipatch
Dentipatch (TN)
Derma Numb
DermaFlex
Desert Harvest Releveum
Diethylaminoaceto-2,6-xylidide
Dilocaine
DivK1c_000174
DivK1c_001323
Dr. Numb
Dr. Richs Numbing
Duncaine
EINECS 205-302-8
ELA-Max
EMBOLEX
Emla
Emla Cream
Esracaine
FT-0082378
Gigi Anesthetic Numbing
Gravocain
H-releve Hemorrhoidal
HMS1791D21
HMS1989D21
HMS2051C21
HMS2089E15
HMS548M19
HSDB 3350
Hawaiian Tropic
Hush Anesthetic
I01-2704
IDI1_000174
IDI1_033829
Isicaina
Isicaine
Jetocaine
KBio1_000174
KBio2_000079
KBio2_001598
KBio2_002647
KBio2_004166
KBio2_005215
KBio2_006734
KBio3_000157
KBio3_000158
KBio3_002224
KBioGR_000079
KBioGR_000599
KBioSS_000079
KBioSS_001598
L-Caine
L0156
L1026_SIGMA
L7757_SIGMA
LIDOCAINE (73-58-6 (MONOHYDROCHLORIDE)
LIDOPEN
LQZ
LS-805
Lanabiotic
 
Laryng-o-jet
Leostesin
Lida-Mantle
Lidall
Lidocaina
Lidocaina [INN-Spanish]
Lidocaine
Lidocaine (JP15/USP/INN)
Lidocaine (VAN)
Lidocaine 4% Cream
Lidocaine Carbonate
Lidocaine Hydrocarbonate
Lidocaine Hydrochloride
Lidocaine Monohydrochloride
Lidocaine [USAN:INN:JAN]
Lidocaine hydrochloride
Lidocainum
Lidocainum [INN-Latin]
Lidocare Mist
Lidocaton
Lidocream 4
Lidocream 5
Lidoderm
Lidoderm 5
Lidoject-1
Lidoject-2
Lifestyles Epic Male Genital Desensitizer
Lignocaine
Lignocainum
Lingocaine
Lmx4
Lmx5
Lopac-L-5647
Lopac0_000669
MLS000069724
MLS000758263
MLS001074177
Maricaine
Maybridge1_002571
MolPort-001-783-478
N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
N-(2,6-dimethylphenyl)-N~2~,N~2~-diethylglycinamide
NCGC00015611-01
NCGC00015611-02
NCGC00015611-03
NCGC00015611-04
NCGC00015611-14
NCGC00022176-05
NCGC00022176-06
NCGC00022176-07
NCGC00022176-08
NCGC00022176-09
NINDS_000174
NSC 40030
NSC40030
Norwood Sunburn Spray
Numb Master Topical Anesthetic
Numb Nuts
Ocean Potion Instant Burn Relief Ice
Octocaine
Octocaine-100
Octocaine-50
Plum Smooth Plumb Numb Gelee
Premjact Male Desensitizer Pound International
Prestwick0_000050
Prestwick1_000050
Prestwick2_000050
Prestwick3_000050
Recticare
Remicaine
Rocephin Kit
Rucaina
S1357_Selleck
SAM001247018
SMR000058189
SPBio_001525
SPBio_002100
STK552033
Simplicity Desensitizing
Simply Numb Endure
Solarcaine
Solarcaine aloe extra burn relief cream
Solcain
Sole Serum
Spectrum2_001343
Spectrum3_001392
Spectrum4_000070
Spectrum5_001549
Spectrum_001118
UNII-98PI200987
WLN: 2N2 & 1VMR B1 F1
Walgreens Aloe Vera Pain Relieving
Xilina
Xilocaina
Xilocaina [Italian]
Xllina
Xycaine
Xylestesin
Xylesthesin
Xylocain
Xylocaine
Xylocaine (TN)
Xylocaine 5% Spinal
Xylocaine CO2
Xylocaine Dental Ointment
Xylocaine Endotracheal
Xylocaine Test Dose
Xylocaine Viscous
Xylocaine-Mpf
Xylocaine-Mpf with Glucose
Xylocaine-mpf
Xylocard
Xylocitin
Xyloneural (free base)
Xylotox
Zcaine Fast Acting Anesthetic
Zilactin-L
Zingo
alfa-Dietilamino-2,6-dimetilacetanilide
alfa-Dietilamino-2,6-dimetilacetanilide [Italian]
alpha-Diethylamino-2,6-dimethylacetanilide
alpha-diethylamino-2,6-dimethylacetanilide
lidocaine
nchembio.65-comp16
╬▒-diethylamino-2,6-dimethylacetanilide
2Peripheral Nervous System Agents18510
3Sodium Channel Blockers1180
4Diuretics, Potassium Sparing1445
5Central Nervous System Depressants10016
6Anesthetics, Local2347
7Anti-Arrhythmia Agents2371
8Anesthetics7385

Interventional clinical trials:

idNameStatusNCT IDPhase
1Motor Cortex Stimulation for the Treatment of Chronic Facial, Upper Extremity, and Throat Pain.RecruitingNCT02321566Phase 1
2Air Stacking vs Glossopharyngeal Breathing in Neuromuscular DiseasesCompletedNCT02500030
3Glossopharyngeal Nerve Block for Awake IntubationCompletedNCT01790464

Search NIH Clinical Center for Glossopharyngeal Neuralgia


Cochrane evidence based reviews: glossopharyngeal nerve diseases

Genetic Tests for Glossopharyngeal Neuralgia

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Anatomical Context for Glossopharyngeal Neuralgia

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MalaCards organs/tissues related to Glossopharyngeal Neuralgia:

33
Tongue, Tonsil, Breast, Cortex, Lung, Colon, Prostate

Animal Models for Glossopharyngeal Neuralgia or affiliated genes

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Publications for Glossopharyngeal Neuralgia

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Articles related to Glossopharyngeal Neuralgia:

(show top 50)    (show all 208)
idTitleAuthorsYear
1
Atypical speech lateralization in adults with developmental coordination disorder demonstrated using functional transcranial Doppler ultrasound. (26917045)
2016
2
Response to letter regarding article, "defining clinically relevant cerebral hemorrhage after thrombolytic therapy for stroke: analysis of the national institute of neurological disorders and stroke tissue-type plasminogen activator trials". (25572410)
2015
3
Next Generation Sequencing Reveals Regulation of Distinct Aedes microRNAs during Chikungunya Virus Development. (24421911)
2014
4
Matrix metalloproteinase 1, 3, and 9 polymorphisms and esophageal squamous cell carcinoma risk. (25391977)
2014
5
Functional mutation analysis provides evidence for a role of REEP1 in lipid droplet biology. (24478229)
2014
6
Safety and efficacy of velaglucerase alfa in Gaucher disease type 1 patients previously treated with imiglucerase. (23339116)
2013
7
Phosphoregulation of the RNA-binding protein Hu antigen R (HuR) by Cdk5 affects centrosome function. (22829587)
2012
8
Irritant-induced migration of Langerhans cells coincides with an IL-10-dependent switch to a macrophage-like phenotype. (21068755)
2011
9
A case report of doxycycline-induced Stevens-Johnson syndrome. (21099409)
2011
10
A nationwide study of three invasive treatments for trigeminal neuralgia. (21239113)
2011
11
Rehabilitation of the elbow extension with motor imagery in a patient with quadriplegia after tendon transfer. (20599055)
2010
12
Effect of the methylenetetrahydrofolate reductase (MTHFR 677C>T) polymorphism on plasma homocysteine concentrations in healthy children is influenced by consumption of folate-fortified foods. (20097536)
2010
13
Aberrant methylation of APC, MGMT, RASSF2A, and Wif-1 genes in plasma as a biomarker for early detection of colorectal cancer. (19773381)
2009
14
Insulin signaling pathways in a patient with insulin resistance of difficult management - a case report. (19941665)
2009
15
Overexpression of the oxygen sensors PHD-1, PHD-2, PHD-3, and FIH Is associated with tumor aggressiveness in pancreatic endocrine tumors. (18927305)
2008
16
TRPM4b channel suppresses store-operated Ca2+ entry by a novel protein-protein interaction with the TRPC3 channel. (18262493)
2008
17
Association of GSK3B with Alzheimer disease and frontotemporal dementia. (18852354)
2008
18
Versatile polyketide enzymatic machinery for the biosynthesis of complex mycobacterial lipids. (17389997)
2007
19
Dip1 inhibits growth and gene transcription in MCF-7 breast cancer cells. (17407970)
2007
20
The RNA-binding protein Sam68 modulates the alternative splicing of Bcl-x. (17371836)
2007
21
The hypoxia-inducible factor HIF-1 promotes intramyocardial expression of VEGF in infants with congenital cardiac defects. (17268888)
2007
22
G501C polymorphism of oxidized LDL receptor gene (OLR1) and ischemic stroke. (17022953)
2006
23
Sensori-neural deafness and hypothyroidism: autoimmunity causing 'pseudo-Pendred syndrome'. (16582570)
2006
24
Sagittal synostosis: I. Preoperative morphology of the skull. (16911991)
2006
25
The evaluation of psoriasis therapy with biologics leads to a revision of the current view of the pathogenesis of this disorder. (17105370)
2006
26
Amyloid precursor protein is involved in staurosporine induced glial differentiation of neural progenitor cells. (16600175)
2006
27
RhoA and p38 MAPK mediate apoptosis induced by cellular cholesterol depletion. (16699960)
2006
28
The significance of tumor markers for proliferation and apoptosis in predicting survival in colorectal cancer. (16400510)
2005
29
Placental and intestinal alkaline phosphatases are receptors for Aeromonas sobria hemolysin. (15715171)
2005
30
Memory reconsolidation and extinction have distinct temporal and biochemical signatures. (15152039)
2004
31
A comparative study of congenital toxoplasmosis between public and private hospitals from UberlAcndia, MG, Brazil. (15057340)
2004
32
Identification of 108 SNPs in TSC, WNK1, and WNK4 and their association with hypertension in a Japanese general population. (15309683)
2004
33
Influence of basic fibroblast growth factor on the proliferation of non-small cell lung cancer cell lines. (15084381)
2004
34
Joubert syndrome co-existing with partial Xp trisomy: review of the literature. (15517825)
2004
35
Evaluation of germline sequence variants of GFRA1, GFRA2, and GFRA3 genes in a cohort of Spanish patients with sporadic medullary thyroid cancer. (12490080)
2002
36
Prevention of oral mucositis and oral candidiasis for patients with cancer treated with chemotherapy: cochrane systematic review. (12214838)
2002
37
PIST: a novel PDZ/coiled-coil domain binding partner for the rho- family GTPase TC10. (11162552)
2001
38
LIGHT, a member of the TNF superfamily, induces morphological changes and delays proliferation in the human rhabdomyosarcoma cell line RD. (11726199)
2001
39
Treatment for malignant pleural effusion of human lung adenocarcinoma by inhibition of vascular endothelial growth factor receptor tyrosine kinase phosphorylation. (10741721)
2000
40
Identification of the CC chemokines TARC and macrophage inflammatory protein-1 beta as novel functional ligands for the CCR8 receptor. (9521068)
1998
41
C1q binds directly and specifically to surface blebs of apoptotic human keratinocytes: complement deficiency and systemic lupus erythematosus revisited. (9144462)
1997
42
Trans-activation by the human aryl hydrocarbon receptor and aryl hydrocarbon receptor nuclear translocator proteins: direct interactions with basal transcription factors. (8794892)
1996
43
Chronic lymphocytic leukemia. (9137957)
1996
44
The validity of DSM-III-R hypochondriasis. (8250682)
1993
45
Structure of DNA-RecA complexes studied by residue differential linear dichroism and fluorescence spectroscopy for a genetically engineered RecA protein. (1518051)
1992
46
Effects of polyactin A on in vitro IL-2 production and responsiveness of human lymphocytes]. (2284949)
1990
47
Oral submucous fibrosis. (3864703)
1985
48
Microprolactinoma and large prolactinoma: are they two different diseases. (4033891)
1985
49
Paroxysmal cold hemoglobinuria with positive treponema immobilization test, report of case. (13471657)
1957
50

Variations for Glossopharyngeal Neuralgia

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Expression for genes affiliated with Glossopharyngeal Neuralgia

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Search GEO for disease gene expression data for Glossopharyngeal Neuralgia.

Pathways for genes affiliated with Glossopharyngeal Neuralgia

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GO Terms for genes affiliated with Glossopharyngeal Neuralgia

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Molecular functions related to Glossopharyngeal Neuralgia according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1receptor bindingGO:00051029.7HNF4A, POMC

Sources for Glossopharyngeal Neuralgia

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet