MCID: GLC077
MIFTS: 18

Glucocorticoid Therapy, Response to

Categories: Genetic diseases

Aliases & Classifications for Glucocorticoid Therapy, Response to

MalaCards integrated aliases for Glucocorticoid Therapy, Response to:

Name: Glucocorticoid Therapy, Response to 54 29 13

Classifications:



External Ids:

OMIM 54 614400

Summaries for Glucocorticoid Therapy, Response to

MalaCards based summary : Glucocorticoid Therapy, Response to An important gene associated with Glucocorticoid Therapy, Response to is GLCCI1 (Glucocorticoid Induced 1). The drugs Prednisone and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include prostate, b cells and t cells.

Description from OMIM: 614400

Related Diseases for Glucocorticoid Therapy, Response to

Symptoms & Phenotypes for Glucocorticoid Therapy, Response to

Clinical features from OMIM:

614400

Drugs & Therapeutics for Glucocorticoid Therapy, Response to

Drugs for Glucocorticoid Therapy, Response to (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 696)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 53-03-2 5865
2
Methylprednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 83-43-2 6741
3
Prednisolone Approved, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 50-24-8 5755
4
Bortezomib Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 179324-69-7 387447 93860
5
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 50-18-0, 6055-19-2 2907
6
Dexamethasone Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-02-2 5743
7
Epirubicin Approved Phase 4,Phase 3,Phase 2 56420-45-2 41867
8
Azithromycin Approved Phase 4,Phase 1,Phase 2 83905-01-5 55185 53477736 447043
9
Telbivudine Approved, Investigational Phase 4 3424-98-4 159269
10
Budesonide Approved Phase 4,Phase 2,Phase 3,Early Phase 1 51333-22-3 63006 5281004
11
Ondansetron Approved Phase 4,Phase 3,Phase 2,Phase 1 99614-02-5 4595
12
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1 50-23-7 5754 657311
13
Leflunomide Approved, Investigational Phase 4,Phase 3,Phase 2 75706-12-6 3899
14
Methotrexate Approved Phase 4,Phase 3,Phase 2,Phase 1 1959-05-2, 59-05-2 126941
15
Mifepristone Approved, Investigational Phase 4,Phase 2,Phase 1 84371-65-3 55245
16
Epinephrine Approved, Vet_approved Phase 4,Phase 2 51-43-4 5816
17 Racepinephrine Approved Phase 4,Phase 2
18
Betamethasone Approved, Vet_approved Phase 4,Phase 3,Phase 2 378-44-9 9782
19
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 2,Phase 3,Phase 1 22916-47-8 4189
20
Azathioprine Approved Phase 4,Phase 3,Phase 2 446-86-6 2265
21
Aprepitant Approved, Investigational Phase 4,Phase 3,Phase 2 170729-80-3 151165 6918365
22
Fosaprepitant Approved Phase 4,Phase 3,Phase 2 172673-20-0 219090
23
rituximab Approved Phase 4,Phase 3,Phase 2,Phase 1 174722-31-7 10201696
24
Benzocaine Approved Phase 4,Phase 3,Phase 2 1994-09-7, 94-09-7 2337
25
Asparaginase Approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 9015-68-3
26
Cytarabine Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1 147-94-4 6253
27
Daunorubicin Approved Phase 4,Phase 3,Phase 2,Phase 1 20830-81-3 30323
28
Mitoxantrone Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 65271-80-9 4212
29
Vincristine Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 2068-78-2, 57-22-7 5978
30
Etoposide Approved Phase 4,Phase 3,Phase 2,Phase 1 33419-42-0 36462
31
Lenograstim Approved Phase 4,Phase 3,Phase 2,Phase 1 135968-09-1
32
Doxorubicin Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 23214-92-8 31703
33
Melphalan Approved Phase 4,Phase 3,Phase 2,Phase 1 148-82-3 4053 460612
34
Cisplatin Approved Phase 4,Phase 3,Phase 2,Phase 1 15663-27-1 84093 441203 2767
35
Gemcitabine Approved Phase 4,Phase 3,Phase 2,Phase 1 95058-81-4 60750
36
Lenalidomide Approved Phase 4,Phase 3,Phase 2,Phase 1 191732-72-6 216326
37
Mechlorethamine Approved Phase 4,Phase 3,Phase 2,Phase 1 51-75-2 4033
38
Fludarabine Approved Phase 4,Phase 3,Phase 2,Phase 1 21679-14-1, 75607-67-9 30751
39
Idarubicin Approved Phase 4,Phase 3,Phase 2 58957-92-9 42890
40
Pegaspargase Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 130167-69-0
41
Ranibizumab Approved Phase 4,Phase 2,Phase 3 347396-82-1 459903
42
Triamcinolone Approved, Vet_approved Phase 4,Phase 2,Phase 3 124-94-7 31307
43
Thioguanine Approved Phase 4,Phase 3,Phase 2 154-42-7 2723601
44
Mycophenolate mofetil Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 128794-94-5 5281078
45
Mycophenolic acid Approved Phase 4,Phase 3,Phase 2,Phase 1 24280-93-1 446541
46
Tacrolimus Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 104987-11-3 445643 439492
47
chloroquine Approved, Vet_approved Phase 4 54-05-7 2719
48
Hydroxychloroquine Approved Phase 4,Phase 3,Phase 1 118-42-3 3652
49
Cycloserine Approved Phase 4 68-41-7 401 6234
50
Ceftibuten Approved Phase 4 97519-39-6 5282241 5282242

Interventional clinical trials:

(show top 50) (show all 1130)

id Name Status NCT ID Phase Drugs
1 Steroids Pharmacokinetics and the Response to Prednisone Therapy in Giant Cell Arteritis Unknown status NCT01400464 Phase 4 Prednisone therapy and pharmacokinetic
2 Efficacy of Systemic Glucocorticoid in the Treatment of Wheezing in Children Unknown status NCT00494624 Phase 4 prednisolone
3 A Study of PAD Versus Velcade, Cyclophosphamide and Dexamethasone (VCD) Treatment in Subjects With Multiple Myeloma Unknown status NCT01868828 Phase 4 PAD;VCD
4 Does a Single Steroid Injection Reduce the Formation of Postmastectomy Seroma Unknown status NCT00307606 Phase 4 Solu-medrol 125 mg
5 A Prospective, Randomized Trial of Intravenous Pulse Versus Sequential Steroid Therapy for Patients With Graves' Orbitopathy Unknown status NCT01969019 Phase 4 methylprednisolone, prednisone
6 Low Dose Steroids in the Treatment of Nephrotic Syndrome Relapse Unknown status NCT02216747 Phase 4 prednisone 60 mg/meter square Body Surface Area;prednisone 45 mg;prednisone 30 mg
7 Steroids In caRdiac Surgery Trial (SIRS Trial) Unknown status NCT00427388 Phase 4 Methylprednisolone
8 The Efficacy of Prednisone and Azithromycin in the Treatment of Patients With Cat Scratch Disease Unknown status NCT01469702 Phase 4 prednison and azithromycin;prednison, azithromycin;prednison, Azenil
9 Prednisolone Priming Study in Patients With Chronic Hepatitis B Unknown status NCT00778596 Phase 4 Prednisolone;Placebo priming
10 Dietetic Versus Topical Steroids for Pediatric Eosinophilic Esophagitis Unknown status NCT01846962 Phase 4 Budesonide;Fluticasone
11 Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Vitrectomy Under Local Anesthesia Unknown status NCT02386059 Phase 4 PLACEBO;Dexamethasone;Ondansetron;Dexamethasone + Ondansetron
12 Single Dose of Dexamethasone in Femur Fractures Unknown status NCT01550146 Phase 4 Dexamethasone acetate;Placebo
13 Effects of Enteral Nutrition and Corticosteroid on Intestinal Flora in Induction Remission of Crohn Disease in Adult Unknown status NCT02056418 Phase 4 corticosteroid
14 Glucocorticoid Therapy Impact on the Inflammatory Response and Clinical Evolution in Patients With Severe Bronchiolitis Completed NCT02571517 Phase 4 Glucocorticoids
15 Comparison of Combination Disease Modifying Antirheumatic Drugs With Methotrexate Therapy in Early Rheumatoid Arthritis Completed NCT02644499 Phase 4 Methotrexate;Leflunomide;Hydroxychloroquine;Prednisolone;Folic Acid
16 Developing Memory Reconsolidation Blockers as Novel Posttraumatic Stress Disorder (PTSD) Treatments Completed NCT01490697 Phase 4 Mifepristone;d-Cycloserine;Placebo-matching Mifepristone;Placebo-matching d-Cycloserine (DCS)
17 Glucocorticoid Receptor Blockade With Mifepristone in Patients With Mild Adrenal Hypercortisolism Completed NCT01990560 Phase 4 Mifepristone
18 Corticoids in Severe Community-Acquired Pneumonia (CAP) Completed NCT00908713 Phase 4 methylprednisolone;Placebo
19 Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata Completed NCT01167946 Phase 4 methylprednisolone sodium succinate;methylprednisolone sodium succinate;methylprednisolone sodium succinate
20 Short Term Efficacy of a Starting Dose of 12.5 mg of Prednisone in Polymyalgia Rheumatica Patients Completed NCT01169597 Phase 4 prednisone
21 Methotrexate and Cyclosporine in Treatment of Early Rheumatoid Arthritis Completed NCT00209859 Phase 4 Methotrexate;Intraarticular betamethasone;Cyclosporine/placebo-cyclosporine
22 Possible Role of Chloroquine to Induce a Complete Remission in the Treatment of Autoimmune Hepatitis: a Randomized Trial Completed NCT02463331 Phase 4 Chloroquine diphosphate;prednisone;azathioprine
23 Effect of Topical Dexamethasone on Histologic Response of Human Dental Pulp Completed NCT02574468 Phase 4 Dexamethasone applied on pulp or Dexamethasone did not applied on pulp
24 Efficacy/Safety/Subject Satisfaction/Duration of Response of Clobetasol Propionate Spray vs Ointment in Plaque Psoriasis Completed NCT00733954 Phase 4 clobetasol propionate spray;clobetasol propionate ointment
25 Olux E Foam and Sorilux Foam Combination Therapy for the Maintenance of Treatment Response in Patients With Moderate Plaque Psoriasis Completed NCT01745133 Phase 4 vehicle foam;calcipotriene;calcipotriene + clobetasol propionate
26 Safety and Efficacy Study of Combination Treatment With Excimer Laser, Clobex Spray, and Vectical Ointment in the Treatment of Psoriasis Completed NCT01012713 Phase 4 Clobex Spray;Vectical Ointment
27 The Evaluation of FeNO for Predicting Response to ICS in Subjects With Non-specific Respiratory Symptoms Completed NCT02294279 Phase 4 Qvar (100 mcg)
28 Aprepitant Versus Ondansetron in Preoperative Triple-therapy Treatment of Nausea and Vomiting Completed NCT01474915 Phase 4 Aprepitant;Ondansetron;Promethazine;Dexamethasone
29 Infliximab as Induction Therapy in Early Rheumatoid Arthritis (IDEA) Completed NCT01308255 Phase 4 Infliximab;Methylprednisolone;Methotrexate
30 A Study of MabThera (Rituximab) in Patients With Rheumatoid Arthritis and an Inadequate Response to Methotrexate Completed NCT01000610 Phase 4 rituximab [MabThera/Rituxan];methotrexate;methylprednisolone
31 Dexamethasone Plus Virtual Reality Exposure Therapy for PTSD Completed NCT01965366 Phase 4 0.5 mg DEX
32 Comparison of Low Dose Versus High Dose Cyclophosphamide as Induction Therapy in the Treatment of Lupus Nephritis Completed NCT02645565 Phase 4 Cyclophosphamide;Azathioprine;Methylprednisolone
33 Efficacy of Calcifediol Supplementation in Asthma Control in Asthmatic Patients With Vitamin D Deficiency (ACViD) Completed NCT02805907 Phase 4 Calcifediol;Placebo
34 LAL-Ph-2000: Treatment of Acute Lymphoblastic Leukemia Chromosome Philadelphia Positive Completed NCT00526305 Phase 4 Vincristine;Daunorubicin;Prednisone;L-Asparaginase;Mitoxantrone;Cytosine Arabinoside;Hydrocortisone;Mercaptopurine;Cyclophosphamide;Dexamethasone
35 Study to Investigate Real Life Effectiveness of Symbicort Maintenance and Reliever Therapy in Asthma Patients Across Asia Completed NCT00939341 Phase 4 Symbicort (Budesonide/Formoterol)
36 High-dose Dexamethasone Versus Conventional Dose Prednisone for Initial Treatment of Primary Immune Thrombocytopenia (ITP) Completed NCT01356511 Phase 4 Prednisone;Dexamethasone
37 LAL-BR/2001: Study Treatment to Low Risk ALL Completed NCT00526175 Phase 4 Prednisone;Vincristine;Daunorubicin;L-Asparaginase;Cyclophosphamide;Methotrexate;Cytosine Arabinoside;Mercaptopurine;VP-16
38 A Comparison of Methotrexate Alone or Combined to Infliximab or to Pulse Methylprednisolone in Early Rheumatoid Arthritis: A Magnetic Resonance Imaging Study Completed NCT00396747 Phase 4 Infliximab, methylprednisolone, methotrexate;Methotrexate;Methotrexate + Methylprednisolone;Methotrexate + Infliximab
39 Medical Polypectomy and Predictors of Response Completed NCT00788749 Phase 4 Prednisolone;Placebo
40 Study of Cabazitaxel Combined With Prednisone and Prophylaxis of Neutropenia Complications in the Treatment of Patients With Metastatic Castration-resistant Prostate Cancer Completed NCT01649635 Phase 4 CABAZITAXEL (XRP6258);Prednisone;Ciprofloxacin;G-CSF (Granulocyte colony-stimulating factor)
41 Odansetron and Dexamethasone Alone vs. Odansetron, Dexamethason and Apreptant to Prevent Nausea Completed NCT00781768 Phase 4 Standard PO ondansetron + dexamethasone;aprepitant (MK-869) + PO ondansetron + dexamethasone
42 Bortezomib/Adriamycine/Melfalan/Prednisone (VAMP)/Thalidomide/Cyclophosphamide/Dexamethasone (TaCyDex) or Bortezomib/Melfalan/Prednisone (V-MP)/TaCyDex) in Refractary or Relapsed Multiple Myeloma Completed NCT00652041 Phase 4 Bortezomib;Thalidomide;Bortezomib
43 Evaluation of Safety of Cabazitaxel (Jevtana) in Patients With Metastatic Hormone Refractory Prostate Cancer Completed NCT02074137 Phase 4 CABAZITAXEL XRP6258;Prednisone;Prednisolone
44 A Randomised, Double Blind, Placebo Controlled, 4 Period, Incomplete Block, Crossover Study Assessing the Dose-response Curve of Fluticasone Propionate in an Antigen Challenge Chamber Completed NCT00848965 Phase 4 Fluticasone propionate;Placebo
45 Docetaxel in the Treatment of Hormone Refractory Prostate Cancer Completed NCT00280098 Phase 4 docetaxel
46 Combination of Cabazitaxel With Prednisolone With Primary Prophylaxis With PEG-G-CSF in Treatment of Patients With Prostate Cancer Completed NCT02441894 Phase 4 CABAZITAXEL XRP6258;PEG-G-CSF;Prednisolone;Dexchlorpheniramine or Diphenhydramine;Ranitidine;Metoclopramide, Granisetron, or Ondansetron;Dexamethasone
47 Evaluation of Anti-inflammatories in the Reduction of Bite Reactions Completed NCT01452997 Phase 4 NSAI treatment;Steroid treatment
48 A Controlled Trial of Mifepristone in Gulf War Veterans With Chronic Multisymptom Illness Completed NCT00691067 Phase 4 mifepristone;Placebos
49 Effect of Symbicort ® on GR in Sputum in COPD Completed NCT01787097 Phase 4 Symbicort®, Formoterol, Budesonide
50 Treatment of Peripheral T-cell Lymphoma Completed NCT01664975 Phase 4 GDPT regimen;CHOP regimen

Search NIH Clinical Center for Glucocorticoid Therapy, Response to

Genetic Tests for Glucocorticoid Therapy, Response to

Genetic tests related to Glucocorticoid Therapy, Response to:

id Genetic test Affiliating Genes
1 Glucocorticoid Therapy, Response to 29

Anatomical Context for Glucocorticoid Therapy, Response to

MalaCards organs/tissues related to Glucocorticoid Therapy, Response to:

39
Prostate, B Cells, T Cells, Breast, Lung, Bone, Brain

Publications for Glucocorticoid Therapy, Response to

Variations for Glucocorticoid Therapy, Response to

ClinVar genetic disease variations for Glucocorticoid Therapy, Response to:

6
id Gene Variation Type Significance SNP ID Assembly Location
1 GLCCI1 NM_138426.3(GLCCI1): c.-559-547G= single nucleotide variant drug response rs37973 GRCh37 Chromosome 7, 8007876: 8007876

Expression for Glucocorticoid Therapy, Response to

Search GEO for disease gene expression data for Glucocorticoid Therapy, Response to.

Pathways for Glucocorticoid Therapy, Response to

GO Terms for Glucocorticoid Therapy, Response to

Sources for Glucocorticoid Therapy, Response to

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....