MCID: GLC003
MIFTS: 63

Glucose Intolerance malady

Gastrointestinal diseases category

Summaries for Glucose Intolerance

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33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 Your small intestine does most of the digesting of the foods you eat. if you have a malabsorption syndrome, your small intestine cannot absorb nutrients from foods. causes of malabsorption syndromes include celiac disease lactose intolerance short bowel syndrome. this happens after surgery to remove half or more of the small intestine. you might need the surgery if you have a problem with the small intestine from a disease, injury, or birth defect. whipple disease, a rare bacterial infection genetic diseases certain medicines symptoms of different malabsorption syndromes can vary. they often include chronic diarrhea, abnormal stools, weight loss, and gas. your doctor may use lab, imaging, or other tests to make a diagnosis. treatment of malabsorption syndromes depends on the cause.

MalaCards: Glucose Intolerance, also known as malabsorption, is related to obesity and diabetes mellitus. An important gene associated with Glucose Intolerance is SERPINA6 (serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 6), and among its related pathways are Glucose / Energy Metabolism and Common Cytokine Receptor Gamma-Chain Family Signaling Pathways. The drug glucomannan and the compounds lipid and fatty acid have been mentioned in the context of this disorder. Affiliated tissues include testes, small intestine and ovary, and related mouse phenotypes are liver/biliary system and homeostasis/metabolism.

Wikipedia:63 Impaired glucose tolerance (IGT) is a pre-diabetic state of hyperglycemia that is associated with... more...

Aliases & Classifications for Glucose Intolerance

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Sources:
8Disease Ontology, 10DISEASES, 44Novoseek, 33MedlinePlus, 60UMLS, 34MeSH, 25ICD10
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Gastrointestinal diseases


Aliases & Descriptions:

glucose intolerance 8 10 44
malabsorption 8 44
impaired glucose tolerance 60
malabsorption of glucose 8
malabsorption syndromes 33
malabsorption syndrome 60
glucose: intolerance 8


External Ids:

Disease Ontology8 DOID:10603
MeSH34 D018149
ICD1025 K90.4

Related Diseases for Glucose Intolerance

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Glucose Intolerance via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 436)
idRelated DiseaseScoreTop Affiliating Genes
1obesity31.4ADRB3, ENPP1
2diabetes mellitus31.0PCK2, RETN, INS, SLC2A4, PAX4, ENPP1
3hepatitis31.0IGFBP1
4hypertension31.0RETN, INS, ADRB3
5pancreatitis30.9INS
6polycystic ovary syndrome30.9CAPN10, INS, SHBG, IGFBP1
7gestational diabetes30.9ADRB3, ADIPOQ, ENPP1, SLC2A4, INS, RETN
8cystic fibrosis30.7INS, RBP4, CAPN10
9type 2 diabetes mellitus30.6SLC2A4, PCK2, IGFBP1, GYS1, LIPE, SHBG
10hyperglycemia30.6RETN, PCK2, IGFBP1, GYS1, PDX1, LSL
11hepatitis c30.5LSL, TXN, ADIPOQ
12atherosclerosis30.4TXN, CAPN10, LSL, RBP4, SHBG, LIPE
13myocardial infarction30.4PDX1, ENPP1, ADIPOQ, LSL, RETN, IGFBP1
14acute myocardial infarction30.4IGFBP1, TXN, RETN
15hypopituitarism30.4SHBG, INS
16acromegaly30.4ADIPOQ, IGFBP1, RETN, INS, LSL, SHBG
17gastritis30.2TXN
18hyperandrogenism30.2INS, LSL, IGFBP1, RETN, SHBG, ADIPOQ
19coronary artery disease30.2ENPP1, ADIPOQ, ADRB3, INS, TXN, RETN
20fatty liver disease30.2RETN, RBP4, INS
21ischemia30.2PAX6, SLC2A4, GCK
22acanthosis nigricans30.2INS, ADIPOQ, SHBG
23diabetic retinopathy30.2INS, IGFBP1
24adenocarcinoma30.2PDX1, SLC2A4, IGFBP1
25leukemia30.2RBP4, PAX6, IGFBP1, PDX1
26prediabetes syndrome30.2ADIPOQ, INS
27hypoglycemia30.0SERPINA6, SLC2A4, INS, PCK2, IGFBP1, GYS1
28hyperthyroidism30.0INS, SERPINA6, LSL, SHBG, RETN
29essential hypertension30.0ADIPOQ, ADRB3, INS, RETN, SHBG
30hyperinsulinism30.0RETN, GCK, IGFBP1, SHBG, LSL, INS
31hypogonadism30.0INS, SHBG, LSL, ADIPOQ
32breast cancer30.0SLC2A4, INS, IGFBP1, ADRB3, SERPINA6, SHBG
33infertility30.0IGFBP1, INS, CAPN10, LSL, SHBG, RETN
34pancreatic cancer30.0INS, PDX1, SLC2A4
35liver cirrhosis30.0SLC2A4, RBP4, LSL, RETN, ADIPOQ
36insulinoma30.0INS, PDX1, GCK, PAX4
37arthritis30.0RETN, TXN, ADIPOQ
38prostate cancer30.0IGFBP1, SHBG
39anovulation30.0SHBG, INS, IGFBP1
40hyperinsulinemic hypoglycemia30.0INS, GCK
41graves' disease30.0SHBG
42alzheimer's disease30.0INS, SHBG, TXN, RBP4
43colorectal cancer30.0TXN, PAX6
44hyperprolactinemia30.0SHBG
45tuberculosis30.0LIPE, LSL
46proteinuria30.0INS, ADIPOQ, RBP4, LSL
47marasmus30.0LSL
48rheumatoid arthritis29.8TXN, ADIPOQ, RETN, SERPINA6
49protein-energy malnutrition29.8IGFBP1, LSL, RBP4
50primary hyperoxaluria29.6ENPP1, ADIPOQ, CAPN10, INS, RBP4, RETN

Graphical network of the top 20 diseases related to Glucose Intolerance:



Diseases related to glucose intolerance

Clinical Features for Glucose Intolerance

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Drugs & Therapeutics for Glucose Intolerance

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

Search CenterWatch for Glucose Intolerance

Drug clinical trials:

Search ClinicalTrials for Glucose Intolerance

Search NIH Clinical Center for Glucose Intolerance

Search CenterWatch for Glucose Intolerance

Inferred drug relations via UMLS60/NDF-RT40:

Genetic Tests for Glucose Intolerance

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Anatomical Context for Glucose Intolerance

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32MalaCards
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MalaCards organs/tissues related to Glucose Intolerance:

32
Testes, Small intestine, Ovary, Liver, Skeletal muscle, Pancreas, Heart, Brain, Pancreatic islet, Hypothalamus, Kidney, Monocytes, Endothelial, Breast, Adipocyte, T cells, Prostate, Bone, Thyroid, Pituitary

Animal Models for Glucose Intolerance or affiliated genes

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36MGI
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MGI Mouse Phenotypes related to Glucose Intolerance:

36
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:000537010.8GCK, SLC2A4, CAPN10, PDX1, LIPE, GYS1
2MP:000537610.8RBP4, LIPE, GYS1, RETN, PDX1, SLC2A4
3MP:000537910.7LIPE, CAPN10, GCK, PAX6, RBP4, SLC2A4
4MP:000537510.7RETN, INS, SLC2A4, ENPP1, ADIPOQ, ADRB3
5MP:000536910.6RBP4, PDX1, INS, SLC2A4, PAX6, ENPP1
6MP:000537810.6PDX1, LIPE, ADIPOQ, ADRB3, ENPP1, GYS1
7MP:000538710.6CAPN10, PDX1, IGFBP1, INS, SLC2A4, PAX6
8MP:000538510.5ENPP1, PAX6, SLC2A4, INS, GYS1, LIPE
9MP:000536710.3GCK, INS, ADIPOQ, SERPINA6, PAX6, PDX1

Publications for Glucose Intolerance

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Sources:
50PubMed
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Articles related to Glucose Intolerance:

(show top 50)    (show all 584)
idTitleAuthorsYear
1
Enhanced lipid oxidation and maintenance of muscle insulin sensitivity despite glucose intolerance in a diet-induced obesity mouse model. (23951235)
2013
2
Orexin-A suppresses postischemic glucose intolerance and neuronal damage through hypothalamic brain-derived neurotrophic factor. (23117790)
2013
3
The utility of urinary myo-inositol as a marker of glucose intolerance. (24377833)
2013
4
An iTRAQ proteomic study reveals an association between diet-induced enhanced fatty acid metabolism and the development of glucose intolerance in prediabetic mice. (23316967)
2013
5
In vivo JNK activation in pancreatic I^-cells leads to glucose intolerance caused by insulin resistance in pancreas. (23349497)
2013
6
Ozone induces glucose intolerance and systemic metabolic effects in young and aged Brown Norway rats. (24103449)
2013
7
Nupr1 deletion protects against glucose intolerance by increasing beta cell mass. (23900510)
2013
8
Fermented tea improves glucose intolerance in mice by enhancing translocation of glucose transporter 4 in skeletal muscle. (23106150)
2012
9
Inflammatory marker levels in obese adolescents with glucose intolerance: increased chitotriosidase activity. (22206738)
2012
10
Comparison between valsartan and amlodipine regarding cardiovascular morbidity and mortality in hypertensive patients with glucose intolerance: NAGOYA HEART Study. (22232134)
2012
11
Maternal cigarette smoke exposure contributes to glucose intolerance and decreased brain insulin action in mice offspring independent of maternal diet. (22076142)
2011
12
HVEM-deficient mice fed a high-fat diet are protected from adipose tissue inflammation and glucose intolerance. (21679708)
2011
13
Chronic reduction of insulin receptors in the ventromedial hypothalamus produces glucose intolerance and islet dysfunction in the absence of weight gain. (21828334)
2011
14
Adipose tissue-specific inhibition of hypoxia-inducible factor 1{alpha} induces obesity and glucose intolerance by impeding energy expenditure in mice. (20716529)
2010
15
Metformin reduces body weight gain and improves glucose intolerance in high-fat diet-fed C57BL/6J mice. (20522960)
2010
16
Glucagon suppression during OGTT worsens while suppression during IVGTT sustains alongside development of glucose intolerance in patients with chronic pancreatitis. (20573586)
2010
17
Comparison of lymphomononuclear cell energy metabolism between healthy, impaired glucose intolerance and type 2 diabetes mellitus patients. (20963562)
2010
18
Hepatic Bax inhibitor-1 inhibits IRE1alpha and protects from obesity-associated insulin resistance and glucose intolerance. (19996103)
2010
19
A systematic review of lifestyle modification and glucose intolerance in the prevention of type 2 diabetes. (20879973)
2010
20
Mechanisms of glucose intolerance in cystic fibrosis. (19538232)
2009
21
Human serum metabonomic analysis reveals progression axes for glucose intolerance and insulin resistance statuses. (19697961)
2009
22
Chronic inhibition of dipeptidyl peptidase-IV with ASP8497 improved the HbA(1c) level, glucose intolerance, and lipid parameter level in streptozotocin-nicotinamide-induced diabetic mice. (18762913)
2009
23
Abdominal visceral adiposity in the first trimester predicts glucose intolerance in later pregnancy. (19389819)
2009
24
Beta-glycosphingolipids improve glucose intolerance and hepatic steatosis of the Cohen diabetic rat. (18940939)
2009
25
Lifestyle changes after oral glucose tolerance test improve glucose intolerance in community-dwelling elderly people after 1 year. (18380685)
2008
26
Metabolic characteristics of glucose intolerance: the critical role of obesity. (17972239)
2008
27
Unrecognized glucose intolerance is not associated with depression. Screening for Impaired Glucose Tolerance study 3 (SIGT 3). (19046230)
2008
28
The Androgen Excess Society guidelines on glucose intolerance in the polycystic ovary syndrome: what do they mean and what should we do? (18619175)
2008
29
Mice with chronically increased circulating ghrelin develop age-related glucose intolerance. (18270302)
2008
30
Impact of treatment with oral calcitriol on glucose intolerance and dyslipidemia(s) in hemodialysis patients. (18974581)
2008
31
Temporal and dietary fat content-dependent islet adaptation to high-fat feeding-induced glucose intolerance in mice. (17161234)
2007
32
Amelioration of obesity and glucose intolerance in high-fat-fed C57BL/6 mice by anthocyanins and ursolic acid in Cornelian cherry (Cornus mas). (16390206)
2006
33
Amelioration of non-alcoholic steatohepatitis and glucose intolerance in ob/ob mice by oral immune regulation towards liver-extracted proteins is associated with elevated intrahepatic NKT lymphocytes and serum IL-10 levels. (16261527)
2006
34
Calcium channel blocker azelnidipine reduces glucose intolerance in diabetic mice via different mechanism than angiotensin receptor blocker olmesartan. (16990512)
2006
35
Variants of ENPP1 are associated with childhood and adult obesity and increase the risk of glucose intolerance and type 2 diabetes. (16025115)
2005
36
Glucose intolerance in young TallyHo mice is induced by leptin-mediated inhibition of insulin secretion. (16288988)
2005
37
Contribution of defects in glucose uptake to carbohydrate intolerance in liver cirrhosis: assessment during physiological glucose and insulin concentrations. (15637182)
2005
38
Deficiency of PDK1 in liver results in glucose intolerance, impairment of insulin-regulated gene expression and liver failure. (15554902)
2005
39
Beta-cell function and insulin resistance evaluated by HOMA in pancreatic cancer subjects with varying degrees of glucose intolerance. (15855820)
2005
40
The Gly482Ser missense mutation of the peroxisome proliferator-activated receptor gamma coactivator-1 alpha (PGC-1 alpha) gene associates with reduced insulin sensitivity in normal and glucose-intolerant obese subjects. (16403952)
2005
41
Diet-induced glucose intolerance in mice with decreased beta-cell ATP-sensitive K+ channels. (15561946)
2004
42
Glucose intolerance and its relation to cardiovascular risk factors among Greenland Inuit. The Greenland Population Study. (15526932)
2004
43
GLP-1 receptor gen "knock out" causes glucose intolerance, but no alterations of eating behavior]. (9381748)
1997
44
The postprandial state: mechanisms of glucose intolerance. (9272609)
1997
45
Long-term effects of fluoxetine on glycemic control in obese patients with non-insulin-dependent diabetes mellitus or glucose intolerance: influence on muscle glycogen synthase and insulin receptor kinase activity. (8786726)
1995
46
Maternal glucose intolerance and the subcutaneous terbutaline pump. (1550166)
1992
47
Improvement of glucose tolerance by minimal doses of glipizide in obese subjects with different degrees of glucose intolerance. (1490690)
1992
48
An asymptomatic, normotensive sipple syndrome patient with glucose intolerance and hypercholesterolemia, and her kindred. (1678022)
1991
49
Hypertension in glucose intolerance and diabetes. (2043226)
1991
50
Association of plasma triglyceride and C-peptide with coronary heart disease in Japanese-American men with a high prevalence of glucose intolerance. (2210122)
1990

Genetic Variations for Glucose Intolerance

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Expression for genes affiliated with Glucose Intolerance

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Glucose Intolerance

Search GEO for disease gene expression data for Glucose Intolerance.

Pathways for genes affiliated with Glucose Intolerance

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Sources:
4Cell Signaling Technology, 52R&D Systems, 53Reactome, 29KEGG, 12EMD Millipore, 37NCBI BioSystems Database, 49PharmGKB, 51QIAGEN
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Pathways related to Glucose Intolerance according to GeneCards/GeneDecks:

(show all 16)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
110.6SLC2A4, PDX1, LIPE, GYS1, PCK2, INS
2
Hide members
10.5INS, RBP4, GYS1, SLC2A4, ADIPOQ, RETN
3
Hide members
10.5PDX1, INS, PAX6, PAX4, GCK
4
Translation Insulin regulation of translation
Hide members
10.5INS, SLC2A4, GYS1, PCK2, GCK, LIPE
5
Hide members
10.5ADIPOQ, PDX1, GCK, SLC2A4, INS
610.5RETN, ADIPOQ, SLC2A4, INS, LIPE, PCK2
710.5LIPE, INS, GYS1, SLC2A4
810.5SLC2A4, ADIPOQ, LIPE, GYS1
910.5GCK, IGFBP1, INS, PDX1
1010.5GCK, PDX1, INS
1110.5GYS1, SLC2A4, LIPE, ENPP1
1210.5GYS1, INS, SLC2A4
1310.5PDX1, IGFBP1, INS
14
Hide members
10.5SLC2A4, PCK2, GYS1, GCK
1510.5ADIPOQ, PCK2, SLC2A4
16
Hide members
10.5GCK, PCK2, SLC2A4

Compounds for genes affiliated with Glucose Intolerance

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Sources:
44Novoseek, 49PharmGKB, 28IUPHAR, 11DrugBank, 24HMDB, 59Tocris Bioscience, 2BitterDB
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Compounds related to Glucose Intolerance according to GeneCards/GeneDecks:

(show top 50)    (show all 144)
idCompoundScoreTop Affiliating Genes
1lipid4411.1SHBG, GCK, CAPN10, LSL, RBP4, LIPE
2fatty acid4411.0SERPINA6, SLC2A4, INS, RETN, PCK2, IGFBP1
3glucose4411.0ENPP1, SERPINA6, PAX4, PAX6, SLC2A4, PCK2
4dexamethasone44 49 28 1114.0ADRB3, TXN, GCK, LSL, SERPINA6, ADIPOQ
5cholesterol44 28 11 2414.0LIPE, IGFBP1, PCK2, RETN, INS, SERPINA6
6glycogen44 2412.0ADIPOQ, ENPP1, INS, RETN, PCK2, IGFBP1
7alanine4411.0ADRB3, ADIPOQ, SERPINA6, PAX6, SLC2A4, INS
8c-peptide4411.0PDX1, SHBG, IGFBP1, RETN, INS, ADIPOQ
9rosiglitazone44 49 28 11 2415.0RETN, INS, SLC2A4, ADIPOQ, PCK2, IGFBP1
10lactate4411.0RBP4, TXN, GCK, LSL, SHBG, LIPE
11metformin44 49 1113.0GCK, LSL, SHBG, IGFBP1, RETN, INS
12testosterone44 59 11 2414.0LSL, ADIPOQ, SERPINA6, SLC2A4, TXN, RBP4
13thyroxine44 2412.0LSL, TXN, RBP4, SHBG, RETN, SERPINA6
14glycerol44 11 2413.0INS, GCK, LSL, SHBG, IGFBP1, LIPE
15dehydroepiandrosterone sulfate4411.0IGFBP1, ADIPOQ, LSL, RBP4, SHBG, SERPINA6
16arginine4411.0SHBG, CAPN10, LSL, IGFBP1, INS, PAX6
17carbohydrates4411.0SHBG, TXN, GCK, ADIPOQ, SERPINA6, INS
18androstenedione44 2411.9IGFBP1, SERPINA6, LSL, RBP4, SHBG, INS
19creatinine4410.9INS, SLC2A4, SHBG, ADIPOQ, RETN, RBP4
20dhea4410.9SHBG, ADIPOQ, INS, RETN, IGFBP1, SERPINA6
21pioglitazone44 49 28 1113.9IGFBP1, SHBG, RBP4, SLC2A4, ADIPOQ, INS
22streptozotocin4410.9GCK, PDX1, PCK2, INS, SLC2A4, ADIPOQ
232-deoxyglucose44 1111.9ADIPOQ, INS, IGFBP1, LIPE, SLC2A4, GCK
24phosphatidylinositol4410.9LSL, PDX1, GYS1, IGFBP1, PCK2, RETN
25norepinephrine44 11 2412.9RETN, LIPE, SLC2A4, ADRB3
26sulfonylurea4410.9ADIPOQ, SLC2A4, INS, PDX1, GCK
27triacylglycerol4410.9PCK2, INS, ADIPOQ, LIPE, RBP4, LSL
2817-hydroxyprogesterone44 2411.9IGFBP1, RETN, SERPINA6, ADIPOQ, SHBG
29estrogen4410.9ADRB3
30triiodothyronine4410.9IGFBP1, SHBG, PCK2, RBP4, LSL, SERPINA6
31serine4410.9SLC2A4, PAX6, RBP4, GCK, TXN, ADIPOQ
32vitamin a44 11 2412.9SERPINA6, PCK2, IGFBP1, RBP4, ADIPOQ, RETN
33thiazolidinedione4410.8ADIPOQ, SLC2A4, PCK2, RETN, INS
34retinoic acid44 2411.8ADIPOQ, PAX6, IGFBP1, RBP4, PDX1, TXN
35uric acid44 2411.8ADRB3
3611beta-hydroxysteroid4410.8RETN, PCK2, ADIPOQ, SLC2A4, SERPINA6
37aicar44 11 2412.8SLC2A4, ADIPOQ, GCK, PCK2, INS
38epinephrine44 11 2412.8LSL, GYS1, ADRB3, INS, LIPE, IGFBP1
39hydrocortisone44 2 59 1113.8ADIPOQ, SERPINA6, IGFBP1, LSL, INS, SHBG
40glycerol 3-phosphate44 2411.8ADIPOQ, SLC2A4, GCK, LIPE, PCK2
41aspartate4410.8ADIPOQ, LIPE, RETN, SHBG, LSL, RBP4
42olanzapine49 44 28 11 2414.7SLC2A4, LSL, ADRB3, ADIPOQ, INS
43adenylate4410.7LIPE, ADIPOQ, TXN, GCK, ADRB3, SHBG
44acipimox44 2811.7INS, ADIPOQ, LSL, LIPE
45glimepiride44 49 1112.6INS, SLC2A4, ADIPOQ, RETN
46sterol4410.6GCK, PCK2, SLC2A4, ADIPOQ, LIPE, RETN
47gliclazide44 49 1112.5GYS1, SLC2A4, ADIPOQ, INS
48forskolin44 49 1112.5PDX1, RETN
49nash4410.4INS, RETN, LSL, ADIPOQ
50progesterone44 59 28 11 2414.2LSL, GCK, IGFBP1, SHBG, RETN, SLC2A4

GO Terms for genes affiliated with Glucose Intolerance

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Sources:
16Gene Ontology
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Cellular components related to Glucose Intolerance according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1extracellular regionGO:00557610.5TXN, RBP4, SHBG, IGFBP1, RETN, INS
2extracellular spaceGO:00561510.3RBP4, IGFBP1, RETN, INS, SERPINA6, ENPP1

Biological processes related to Glucose Intolerance according to GeneCards/GeneDecks:

(show all 19)
idNameGO IDScoreTop Affiliating Genes
1glucose homeostasisGO:04259310.9ADIPOQ, GCK, PDX1, RBP4, SLC2A4, PAX6
2cellular response to insulin stimulusGO:03286910.8CAPN10, SLC2A4, ENPP1, ADIPOQ, GCK
3glucose metabolic processGO:00600610.8GYS1, PDX1, PCK2, INS, ADIPOQ
4positive regulation of insulin secretionGO:03202410.8RBP4, PDX1, CAPN10, GCK
5endocrine pancreas developmentGO:03101810.8GCK, PDX1, INS, PAX4
6negative regulation of gluconeogenesisGO:04572110.8GCK, INS, ADIPOQ
7generation of precursor metabolites and energyGO:00609110.8ADIPOQ, ADRB3, ENPP1, PDX1
8positive regulation of glucose importGO:04632610.8CAPN10, INS, ADIPOQ
9small molecule metabolic processGO:04428110.8ENPP1, INS, GCK, LIPE, TXN, GYS1
10brown fat cell differentiationGO:05087310.8SLC2A4, ADIPOQ, ADRB3
11carbohydrate metabolic processGO:00597510.7ADRB3, GCK, SLC2A4, GYS1, PCK2
12detection of glucoseGO:05159410.7GCK, PDX1
13glucose transportGO:01575810.7GCK, INS, SLC2A4
14negative regulation of protein autophosphorylationGO:03195310.6ADIPOQ, ENPP1
15response to ethanolGO:04547110.6ADIPOQ, RBP4, SLC2A4
16positive regulation of glycolysisGO:04582110.5INS, GCK
17positive regulation of glycogen biosynthetic processGO:04572510.5GCK, INS
18organ morphogenesisGO:00988710.4PAX6, PAX4, PDX1
19positive regulation of cellular protein metabolic processGO:03227010.2ADIPOQ, INS

Molecular functions related to Glucose Intolerance according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1protein bindingGO:00551510.6ADRB3, TXN, GCK, RBP4, LIPE, GYS1
2glucose bindingGO:00553610.4GCK, GYS1
3hormone activityGO:00517910.2ADIPOQ, INS, RETN

Products for genes affiliated with Glucose Intolerance

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  • Antibodies
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Sources for Glucose Intolerance

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet