Aliases & Classifications for Gonadoblastoma

About this section

Aliases & Descriptions for Gonadoblastoma:

Name: Gonadoblastoma 10 47 12 36 65

Characteristics:

HPO:

61


Classifications:



External Ids:

Disease Ontology10 DOID:3301
MeSH36 D018238
SNOMED-CT59 74751003
NCIt42 C3754
UMLS65 C0206661

Summaries for Gonadoblastoma

About this section
Wikipedia:68 A gonadoblastoma is a complex neoplasm composed of a mixture of gonadal elements, such as large... more...

MalaCards based summary: Gonadoblastoma is related to ovarian gonadoblastoma and testicular gonadoblastoma, and has symptoms including abnormality of metabolism/homeostasisand gonadoblastoma. An important gene associated with Gonadoblastoma is TSPY1 (Testis Specific Protein, Y-Linked 1), and among its related pathways is Folate biosynthesis. Affiliated tissues include prostate, t cells and endothelial, and related mouse phenotype reproductive system.

Disease Ontology:10 A cell type benign neoplasm that is composed of a mixture of gonadal elements.

Related Diseases for Gonadoblastoma

About this section

Diseases related to Gonadoblastoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 273)
idRelated DiseaseScoreTop Affiliating Genes
1ovarian gonadoblastoma12.4
2testicular gonadoblastoma12.4
3wagr syndrome11.7
4testicular spermatocytic seminoma10.4SRY, TSPY1
5swyer-james syndrome10.4SRY, TSPY1
6frasier syndrome10.4
746 xx gonadal dysgenesis10.3FOXL2, SRY
8cerebritis10.3
9breast-ovarian cancer, familial, 210.3FOXL2, SRY
10lung cancer10.2
11lymphoma10.2
1246 xy gonadal dysgenesis10.2FOXL2, SRY, TSPY1
13myocardial infarction10.1
14breast cancer10.1
15hepatitis10.1
16ischemia10.1
17tuberculosis10.1
18nephrotic syndrome, type 410.1SRY, WT1
19ovary leiomyosarcoma10.1KIT, WT1
20osteogenesis imperfecta-retinopathy-seizures-intellectual disability syndrome10.1KIT, WT1
21anaerobic meningitis10.1ALPP, ALPPL2
22breast adenocarcinoma10.1ALPP, ALPPL2
23cervical adenitis10.1ALPP, ALPPL2
24internal auditory canal meningioma10.1ALPP, ALPPL2
25malignant histiocytosis10.1ALPP, ALPPL2
26angiostrongyliasis10.1ALPP, ALPPL2
27rapidly progressive glomerulonephritis10.1KIT, WT1
28achondrogenesis10.1ALPP, ALPPL2
29arteritic anterior ischemic optic neuropathy10.1ALPP, ALPPL2
30fibrogenesis imperfecta ossium10.1ALPP, ALPPL2
31mixed cell type adenoma of parathyroid10.1ALPP, ALPPL2
32xanthogranulomatous cholecystitis10.1ALPP, ALPPL2
33axial osteomalacia10.1ALPP, ALPPL2
34brawny scleritis10.1ALPP, ALPPL2
35larynx carcinoma in situ10.1ALPP, ALPPL2
36swine influenza10.1ALPP, ALPPL2
37gingival disease10.1ALPP, ALPPL2
38sebaceous breast carcinoma10.1KIT, WT1
39bartholin's gland adenocarcinoma10.1ALPP, ALPPL2
40central nervous system germ cell tumor10.1ALPP, ALPPL2
41venezuelan hemorrhagic fever10.1ALPP, ALPPL2
42diamond-blackfan anemia 410.1ALPP, ALPPL2
43alzheimer disease-210.1ALPP, ALPPL2
44paracoccidioidomycosis10.1ALPP, ALPPL2
45central nervous system sarcoma10.1ALPP, ALPPL2
46bile duct disease10.1ALPP, ALPPL2
47seminoma10.1ALPP, ALPPL2
48disease of mental health10.1FOXL2, SRY
49biliary tract disease10.1ALPP, ALPPL2
50leber congenital amaurosis 310.1ALPP, ALPPL2

Graphical network of the top 20 diseases related to Gonadoblastoma:



Diseases related to gonadoblastoma

Symptoms for Gonadoblastoma

About this section

HPO human phenotypes related to Gonadoblastoma:

id Description Frequency HPO Source Accession
1 abnormality of metabolism/homeostasis HP:0001939
2 gonadoblastoma HP:0000150

Drugs & Therapeutics for Gonadoblastoma

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Gonadoblastoma


Cochrane evidence based reviews: gonadoblastoma

Genetic Tests for Gonadoblastoma

About this section

Anatomical Context for Gonadoblastoma

About this section

MalaCards organs/tissues related to Gonadoblastoma:

33
Prostate, T cells, Endothelial, Kidney, Liver, Testes, Thyroid

Animal Models for Gonadoblastoma or affiliated genes

About this section

MGI Mouse Phenotypes related to Gonadoblastoma:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053897.4ALPPL2, FOXL2, KIT, SLC22A3, TSPYL2, WT1

Publications for Gonadoblastoma

About this section

Articles related to Gonadoblastoma:

(show top 50)    (show all 246)
idTitleAuthorsYear
1
Autonomic arousal in children of parents with and without social anxiety disorder: a high-risk study. (27133173)
2016
2
Sunitinib-associated Pancreatic Atrophy in Patients with Gastrointestinal Stromal Tumor: A Toxicity with Prognostic Implications Detected at Imaging. (27192462)
2016
3
Atypical Varicella in a Patient With Wolf-Hirschhorn Syndrome. (25673626)
2015
4
Extracorporeal Membrane Oxygenation as a Bridge to Surgery for Infective Endocarditis Complicated by Aorto-Atrial Fistula and Cardiopulmonary Collapse. (26504445)
2015
5
ABCB1 polymorphisms predict imatinib response in chronic myeloid leukemia patients: a systematic review and meta-analysis. (25245580)
2015
6
Liver Bid-suppression for treatment of fibrosis associated with nonalcoholic steatohepatitis. (26555271)
2015
7
Anti-inflammatory cytokine interleukin-10 increases resistance to brain ischemia through modulation of ischemia-induced intracellular CaA^a8_ response. (24796809)
2014
8
The role of dendritic cells in immunity against primary herpes simplex virus infections. (25374562)
2014
9
IL-17 signaling accelerates the progression of nonalcoholic fatty liver disease in mice. (24115079)
2013
10
Overexpression of pendrin in intercalated cells produces chloride-sensitive hypertension. (23766534)
2013
11
The effect of duodenojejunal bypass for type 2 diabetes mellitus patients below body mass index 25 kg/m(2): one year follow-up. (24020019)
2013
12
Metabonomics reveals drastic changes in anti-inflammatory/pro-resolving polyunsaturated fatty acids-derived lipid mediators in leprosy disease. (23967366)
2013
13
Acupuncture for pain in endometriosis. (24346786)
2013
14
Utilizing signature-score to identify oncogenic pathways of cholangiocarcinoma. (23905013)
2013
15
Risk factors for congenital hypothyroidism in Egypt: results of a population case-control study (2003-2010). (23793431)
2013
16
SLE with diffuse alveolar hemorrhage, microangiopathic hemolytic anemia and acute renal failure. (22730045)
2012
17
Mutational analysis of HRAS and KRAS genes in oral carcinoma cell lines. (21607592)
2012
18
Malignant fibrous histiocytoma masquerading as gluteal abscess. (22202512)
2011
19
Interleukin-8 mediates resistance to antiangiogenic agent sunitinib in renal cell carcinoma. (20103651)
2010
20
Incidence and prevalence of psoriatic arthritis, ankylosing spondylitis, and reactive arthritis in the first descriptive population-based study in the Czech Republic. (20476864)
2010
21
Identification of dynein light chain road block-1 as a novel interaction partner with the human reduced folate carrier. (19571232)
2009
22
Key role of a PtdIns-4,5P2 micro domain in ionic regulation of the mammalian heart Na+/Ca2+ exchanger. (19394081)
2009
23
Hormonal treatment of male infertility: promises and pitfalls. (18930905)
2009
24
Persistence of mumps antibodies after 2 doses of measles-mumps-rubella vaccine. (19113988)
2009
25
Interactions between genotype and retrospective ADHD symptoms predict lifetime smoking risk in a sample of young adults. (18188752)
2008
26
A defect in the thymidine kinase 2 gene causing isolated mitochondrial myopathy without mtDNA depletion. (17951082)
2008
27
Deep venous thrombosis and inferior vena cava agenesis causing double crush sciatic neuropathy in BehAset's disease. (18848486)
2008
28
I had surgery in 2005 to treat my enlarged prostate. The procedure was transurethral resection of the prostate. Things have worked out pretty well, but I'm wondering how long I can expect the improvement in urine flow to last? (17402156)
2007
29
Possible involvement of cytokine gene polymorphisms in fulminant hepatitis. (17559370)
2007
30
Association of interferon-gamma and interleukin-4 gene polymorphisms with susceptibility to brucellosis in Iranian patients. (17566759)
2007
31
Analysis of autophosphorylating kinase activities of Arabidopsis and human cryptochromes. (17073458)
2006
32
Screening of the CAPN3 gene in patients with possible LGMD2A. (16650086)
2006
33
Immunopathological mechanisms in dengue and dengue hemorrhagic fever. (16940865)
2006
34
Emergence of W135 meningococcal meningitis in Ghana. (16359402)
2005
35
Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins. (15024025)
2004
36
Avascular necrosis of the femoral head in a HIV-1 infected patient receiving lopinavir/ritonavir. (14659664)
2003
37
Clinical, biochemical and molecular genetic data in five children with Gitelman's syndrome. (11456284)
2001
38
Two novel human and mouse DNA polymerases of the polX family. (10982892)
2000
39
Differential regional effects of methamphetamine on the activities of tryptophan and tyrosine hydroxylase. (9930738)
1999
40
Hemoglobin based oxygen carrying solution stability in extracorporeal circulation: an in vitro evaluation and implications for clinical use. (9617945)
1998
41
Immunological heterogeneity in type I diabetes: presence of distinct autoantibody patterns in patients with acute onset and slowly progressive disease. (9726590)
1998
42
Is serum tumor marker half-life a guide to prognosis in metastatic nonseminomatous germ cell tumors? (9329598)
1997
43
In vivo modulation of murine serum tumour necrosis factor and interleukin-6 levels during endotoxemia by oestrogen agonists and antagonists. (7590877)
1995
44
Chronic MPTP treatment reproduces in baboons the differential vulnerability of mesencephalic dopaminergic neurons observed in Parkinson's disease. (7898660)
1994
45
Renal tubular antiproteinase (alpha-1-antitrypsin and alpha-1-antichymotrypsin) response in tubulo-interstitial damage. (7504211)
1993
46
Regulation of the concentration of free arachidonic acid in homogenates of human platelets. (1632309)
1992
47
cDNA cloning, sequence analysis, and chromosomal localization of human carnitine palmitoyltransferase. (1961767)
1991
48
Pseudohypoparathyroidism: case report. (1881816)
1991
49
Atrial natriuretic factor does not improve the outcome of cadaveric renal transplantation. (1832982)
1991
50
Septic cavernous and lateral sinus thrombosis: modern diagnostic and therapeutic principles. (3058845)
1988

Variations for Gonadoblastoma

About this section

Expression for genes affiliated with Gonadoblastoma

About this section
Search GEO for disease gene expression data for Gonadoblastoma.

Pathways for genes affiliated with Gonadoblastoma

About this section

Pathways related to Gonadoblastoma according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.3ALPP, ALPPL2

GO Terms for genes affiliated with Gonadoblastoma

About this section

Biological processes related to Gonadoblastoma according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1sex determinationGO:00075309.7SRY, WT1

Sources for Gonadoblastoma

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet