MCID: GRN010
MIFTS: 47

Granular Cell Tumor malady

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Granular Cell Tumor

Aliases & Descriptions for Granular Cell Tumor:

Name: Granular Cell Tumor 12 50 52 42 14 69
Granular Cell Carcinoma 12 14
Giant Granulocellular Abrikosov's Tumor 50
Malignant Variant of Abrikosov's Tumor 50
Abrikosoff's Granulous Cell Tumor 50
Granular Cell Adenocarcinoma 12
Neoplasm of Granular Cell 12
Carcinoma, Granular Cell 69
Granular Cell Tumor Nos 12
Abrikosoff's Tumor 50
Abrikosov’s Tumor 50
Abrikosov's Tumor 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2411 DOID:4903
NCIt 47 C3474 C3681

Summaries for Granular Cell Tumor

NIH Rare Diseases : 50 granular cell tumors (gcts) are soft tissue tumors that can occur anywhere in the body. they are thought to arise from the cells that surround and insulate the nerve cells in our body (schwann cells). most granular cell tumors are benign (non-cancerous), although some may be locally aggressive. less than 2% are malignant (cancerous), but these are aggressive and often are associated with a poor prognosis. gcts affect females more often than males and usually present as a solitary painless mass. a few individuals have multiple gcts. in most cases, these tumors are located in the skin of the head and neck, especially inside the mouth (70%), the tongue being the most common site. they may also occur in the breast, heart, pituitary gland, stomach, esophagus, genitalia, and upper respiratory tract. gcts may be  part of some genetic syndromes, such as leopard syndrome and neurofibromatosis. complete surgical removal of the tumor is usually curative, but in some cases the tumors may recur. last updated: 10/25/2016

MalaCards based summary : Granular Cell Tumor, also known as granular cell carcinoma, is related to vulvar granular cell tumor and gastrointestinal stromal tumor. An important gene associated with Granular Cell Tumor is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Cytoskeleton remodeling Neurofilaments. The drugs Cisplatin and Gemcitabine have been mentioned in the context of this disorder. Affiliated tissues include breast, tongue and skin.

Disease Ontology : 12 A carcinoma that derives from epithelial cells, with polygonal accumulation of secondary lysosomes in the cytoplasm.

Wikipedia : 71 Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue... more...

Related Diseases for Granular Cell Tumor

Diseases in the Granular Cell Tumor family:

Congenital Granular Cell Tumor

Diseases related to Granular Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 228)
id Related Disease Score Top Affiliating Genes
1 vulvar granular cell tumor 33.4 ENO2 UCHL1
2 gastrointestinal stromal tumor 29.2 DES ENO2 S100B UCHL1 VIM
3 granular cell leiomyosarcoma 29.0 ENO2 GFAP INHA S100B
4 congenital granular cell tumor 12.1
5 malignant gastric granular cell tumor 12.0
6 breast granular cell tumor 12.0
7 skin granular cell tumor 12.0
8 neurohypophysis granular cell tumor 11.9
9 myoblastoma 11.3
10 congenital epulis 11.3
11 malignant granular cell myoblastoma 11.2
12 malignant granular cell skin tumor 11.1
13 cardiac granular cell neoplasm 11.1
14 mediastinal granular cell myoblastoma 11.1
15 malignant granular cell esophageal tumor 10.9
16 autosomal recessive stickler syndrome 10.3 ENO2 VIM
17 13q12.3 microdeletion syndrome 10.3 DES VIM
18 nutritional deficiency disease 10.3 CD68 VIM
19 malignant mixed mullerian tumor 10.3 DES ENO2
20 breast rhabdomyosarcoma 10.3 DES ENO2
21 inflammatory linear verrucous epidermal nevus 10.3 DES VIM
22 lymphomatous thyroiditis 10.3 DES VIM
23 cerebral arterial disease 10.3 CD68 ENO2
24 osteomyelitis 10.3 DES VIM
25 congenital myasthenic syndrome 10.3 DES VIM
26 marfanoid hypermobility syndrome 10.3 DES VIM
27 gallbladder pleomorphic giant cell adenocarcinoma 10.3 CD68 ENO2
28 tanycytic ependymoma 10.3 DES VIM
29 heart leiomyosarcoma 10.3 CD68 DES
30 glaucoma iridogoniodysgenesia 10.3 CD68 DES
31 ossifying fibromyxoid tumor 10.3 ENO2 VIM
32 biemond syndrome 10.3 DES VIM
33 liver angiosarcoma 10.3 DES VIM
34 differentiating neuroblastoma 10.3 ENO2 VIM
35 intestinal obstruction 10.3 DES VIM
36 pinta disease 10.3 CD68 ENO2
37 petrous apex meningioma 10.3 DES VIM
38 male urethral cancer 10.3 DES VIM
39 coronary stenosis 10.2 DES VIM
40 sebaceous adenoma 10.2 DES VIM
41 anal gland neoplasm 10.2 DES VIM
42 episodic ataxia 10.2 CD68 DES
43 esophagitis 10.2
44 glomangioma 10.2 DES VIM
45 lymphangiosarcoma 10.2 INHA VIM
46 lupus - neurological sequelae 10.2 S100B VIM
47 omodysplasia 2 10.2 DES VIM
48 lipid-rich carcinoma 10.2 CD68 ENO2
49 isolated anterior cervical hypertrichosis 10.2 SERPINA3 VIM
50 jejunal neuroendocrine tumor 10.2 S100B VIM

Graphical network of the top 20 diseases related to Granular Cell Tumor:



Diseases related to Granular Cell Tumor

Symptoms & Phenotypes for Granular Cell Tumor

Drugs & Therapeutics for Granular Cell Tumor

Drugs for Granular Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 245)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4 15663-27-1 84093 441203 2767
2
Gemcitabine Approved Phase 4,Phase 3 95058-81-4 60750
3
Pemetrexed Approved, Investigational Phase 4,Phase 3,Early Phase 1 150399-23-8, 137281-23-3 446556 60843
4
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
5
Epirubicin Approved Phase 4 56420-45-2 41867
6
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 59-30-3 6037
7
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 54575, 6560146 143
8
Docetaxel Approved May 1996, Investigational Phase 4,Phase 3,Phase 1,Phase 2 114977-28-5 148124 9877265
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Antimetabolites Phase 4,Phase 2,Phase 3,Phase 1
11 Antimetabolites, Antineoplastic Phase 4,Phase 2,Phase 3,Phase 1
12 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Folic Acid Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
14 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
15 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Vitamin B Complex Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
17 Alkylating Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
18 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
19 Antineoplastic Agents, Alkylating Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
20 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
21 Topoisomerase Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
22 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1
23 Antimitotic Agents Phase 4,Phase 3
24 Folate Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
25 Vitamin B9 Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
26
Ketamine Approved, Vet_approved Phase 3 6740-88-1 3821
27
Cefepime Approved Phase 3 88040-23-7 5479537
28
Levofloxacin Approved, Investigational Phase 3 100986-85-4 149096
29
Ofloxacin Approved Phase 3 82419-36-1 4583
30
Carboplatin Approved Phase 2, Phase 3,Phase 1 41575-94-4 10339178 498142 38904
31
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
32
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
33
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
34
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
35
Vinorelbine Approved, Investigational Phase 3 71486-22-1 60780 44424639
36
Darbepoetin alfa Approved, Investigational Phase 3,Phase 2 11096-26-7, 209810-58-2
37
Iron Approved Phase 3,Phase 1,Phase 2 7439-89-6 23925
38
Dalteparin Approved Phase 3 9041-08-1
39
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
40
Ondansetron Approved Phase 3 99614-02-5 4595
41
Dextromethorphan Approved Phase 3 125-71-3 5360696 5362449
42
Guaifenesin Approved, Vet_approved Phase 3,Phase 2 93-14-1 3516
43
Morphine Approved, Investigational Phase 3 57-27-2 5288826
44
Doxorubicin Approved, Investigational Phase 2, Phase 3,Phase 1 23214-92-8 31703
45
Ifosfamide Approved Phase 2, Phase 3,Phase 1 3778-73-2 3690
46
Mechlorethamine Approved Phase 2, Phase 3,Phase 1 51-75-2 4033
47
Busulfan Approved, Investigational Phase 2, Phase 3,Early Phase 1 55-98-1 2478
48
Etoposide Approved Phase 2, Phase 3,Phase 1,Early Phase 1 33419-42-0 36462
49
Fludarabine Approved Phase 2, Phase 3, Phase 1 21679-14-1, 75607-67-9 30751
50
Thiotepa Approved Phase 2, Phase 3,Phase 1 52-24-4 5453

Interventional clinical trials:

(show top 50) (show all 139)
id Name Status NCT ID Phase
1 Chemotherapy Combined With Yangzhengxiaoji Capsule in Patients With Advanced Non-Small Cell Lung Cancer Unknown status NCT02195453 Phase 4
2 Huaier Granule in Treating Women With Triple Negative Breast Cancer Recruiting NCT02615457 Phase 4
3 Neoadjuvant Chemotherapy With or Without Huaier Granule in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery Recruiting NCT02627248 Phase 4
4 Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain Unknown status NCT01316744 Phase 3
5 Levofloxacin Compared With Cefepime in Treating Cancer Patients With Fever and Neutropenia Unknown status NCT00020865 Phase 3
6 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3
7 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3
8 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3
9 Efficacy Study of Integrated TCM Combined With Chemotherapy in Postoperative NSCLC Patients Completed NCT01441752 Phase 3
10 Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer Completed NCT00070382 Phase 3
11 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3
12 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3
13 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
14 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3
15 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3
16 Personalized Information or Basic Information in Helping Patients Make Decisions About Participating in a Clinical Trial Completed NCT00750009 Phase 3
17 Treatment for Chronic Pain in Patients With Advanced Cancer Completed NCT00003687 Phase 3
18 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-Rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3
19 Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer Active, not recruiting NCT00003816 Phase 2, Phase 3
20 Clinical Study of Chinese Medicine Plus Chemotherapy Maintenance in Advanced Non Small Cell Lung Cancer Enrolling by invitation NCT02900742 Phase 3
21 Songyou Granule and Transarterial Chemoembolization for Hepatocellular Carcinoma Unknown status NCT00805896 Phase 2
22 Brentuximab Vedotin + Rituximab as Frontline Therapy for Pts w/ CD30+ and/or EBV+ Lymphomas Unknown status NCT01805037 Phase 1, Phase 2
23 Cyclosporine in Treating Patients With Low Blood Counts Caused By Hematologic Cancer Completed NCT00031980 Phase 2
24 Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant Completed NCT00110045 Phase 2
25 Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies Completed NCT01093586 Phase 2
26 Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer Completed NCT00237627 Phase 1, Phase 2
27 Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer Completed NCT00823524 Phase 1, Phase 2
28 Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer Completed NCT00003406 Phase 1, Phase 2
29 Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer Completed NCT00006225 Phase 1, Phase 2
30 506U78 in Treating Patients With Chronic Lymphocytic Leukemia That Has Not Responded to Fludarabine or Alkylating Agents Completed NCT00003635 Phase 2
31 Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Completed NCT01258998 Phase 2
32 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00005804 Phase 2
33 Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer Completed NCT00002504 Phase 2
34 Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer Completed NCT00255749 Phase 2
35 Epoetin Alfa or Darbepoetin Alfa in Treating Patients With Anemia Caused by Chemotherapy Completed NCT00416624 Phase 2
36 Combination Chemotherapy Followed By Alemtuzumab in Treating Patients With Chronic Lymphocytic Leukemia or Prolymphocytic Leukemia Completed NCT00278213 Phase 2
37 Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies Recruiting NCT01643603 Phase 1, Phase 2
38 Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphoma Recruiting NCT01609816 Phase 1, Phase 2
39 Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies Recruiting NCT01760655 Phase 2
40 Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies Recruiting NCT01839916 Phase 2
41 A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Recruiting NCT01384513 Phase 2
42 QUILT-3.009: Study of aNK Infusions in Combination With ALT-803 in Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC) Recruiting NCT02465957 Phase 2
43 Biological Therapy in Treating Patients at High-Risk or With Lymphoma, Lymphoproliferative Disease, or Malignancies Recruiting NCT00002663 Phase 1, Phase 2
44 Alemtuzumab (Campath ) to Treat T-Large Granular Lymphocyte Leukemia Recruiting NCT00345345 Phase 2
45 Combination Adenovirus + Pembrolizumab to Trigger Immune Virus Effects Recruiting NCT02798406 Phase 2
46 CAR-pNK Cell Immunotherapy in CD7 Positive Leukemia and Lymphoma Recruiting NCT02742727 Phase 1, Phase 2
47 Prospective, Multicentric, Phase II Randomized Controlled Trial on Two Parallel Groups Comparing the Efficacy of Two Immunosuppressive Drugs (Methotrexate, Cyclophosphamide) in Large Granular Lymphocytes Leukemia Recruiting NCT01976182 Phase 2
48 Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies Active, not recruiting NCT00040846 Phase 2
49 Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer Active, not recruiting NCT00006251 Phase 1, Phase 2
50 Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant Active, not recruiting NCT00078858 Phase 1, Phase 2

Search NIH Clinical Center for Granular Cell Tumor

Cochrane evidence based reviews: granular cell tumor

Genetic Tests for Granular Cell Tumor

Anatomical Context for Granular Cell Tumor

MalaCards organs/tissues related to Granular Cell Tumor:

39
Breast, Tongue, Skin, Pituitary, Heart, Colon, Thyroid

Publications for Granular Cell Tumor

Articles related to Granular Cell Tumor:

(show top 50) (show all 645)
id Title Authors Year
1
Extra-tongue oral granular cell tumor: Histological and immunohistochemical aspect. ( 27918739 )
2017
2
Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report. ( 28057062 )
2017
3
Esophageal Granular Cell Tumor: A Case Report and Review of Literature. ( 27752408 )
2016
4
S-100 Negative Granular Cell Tumor (So-called Primitive Polypoid Non-neural Granular Cell Tumor) of the Oral Cavity. ( 27709427 )
2016
5
Granular Cell Tumor of the Bladder: A Rare Neoplasm Managed With Robotic Partial Cystectomy Using Near-infrared Filter Guidance. ( 27894977 )
2016
6
Granular cell tumor in a child: An uncommon cutaneous presentation. ( 27730035 )
2016
7
A rare laryngeal tumor in a patient with thyroid papillary cancer: granular cell tumor. ( 27068886 )
2016
8
Congenital granular cell tumor in a child with tetralogy of Fallot. ( 27434473 )
2016
9
LEOPARD syndrome and multiple granular cell tumors: An underreported association? ( 26728819 )
2016
10
Benign Granular Cell Tumor of Breast. ( 27124422 )
2016
11
Erratum: LEOPARD syndrome and multiple granular cell tumors: An underreported association? ( 26924415 )
2016
12
Granular cell tumor of cecum. ( 27324518 )
2016
13
Granular cell tumor presenting in the scrotum of a pediatric patient: a case report and review of the literature. ( 27259474 )
2016
14
Unusual Granular Cell Tumor of the Trachea Coexisting With Papillary Thyroid Carcinoma and Masquerading as Tracheal Invasion of Recurred Thyroid Carcinoma: A Case Report. ( 27149467 )
2016
15
Abrikossoff's tumor mimicking endometrial tumor--literature review and case report of the first described granular cell tumor in scar tissue after caesarean section. ( 27172759 )
2016
16
Granular Cell Tumor of the Common Hepatic Duct as an Unusual Cause of Jaundice in a Hepatitis C Patient. ( 26958564 )
2016
17
Computed tomography and magnetic resonance imaging findings of intraorbital granular cell tumor (Abrikossoff's tumor): a case report. ( 27176551 )
2016
18
A Rare Case of a Primary Cutaneous Desmoplastic Atypical Granular Cell Tumor. ( 27759691 )
2016
19
Metachronous Occurrence of Granular Cell Tumor in Breast Skin and Scalp: Diagnostic Challenging Differentiating Benign from Malignant and a Literature Review. ( 26881167 )
2016
20
Synchronous existence of granular cell tumor and small cell carcinoma of lung: An unusual entity. ( 26960647 )
2016
21
Granular Cell Tumor Within an Ovarian Mature Cystic Teratoma: Report of a Unique Case and Review of the Literature. ( 27750257 )
2016
22
Fine-needle aspiration cytology of cutaneous granular cell tumor: Report of two cases with special emphasis on cytological differential diagnosis. ( 27011439 )
2016
23
Vulvar granular cell tumor. ( 27510686 )
2016
24
Esophageal Granular Cell Tumor: A Benign Tumor or an Insidious Cause for Concern? ( 27999519 )
2016
25
Slowly Growing Nodule on the Trunk: Cutaneous Granular Cell Tumor. ( 27504442 )
2016
26
Endoscopic resection of rectal granular-cell tumor using elastic band ligation. ( 26864296 )
2016
27
Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor. ( 26753850 )
2016
28
Granular cell tumor in male breast masquerading as atypical apocrine neoplasm: A potential diagnostic pitfall in fine needle aspiration cytology. ( 27016396 )
2016
29
Granular cell tumor in two oral anatomic sites. ( 27007285 )
2016
30
Atypical granular cell tumor in the maxilla: The first report of primary intraosseous granular cell tumor. ( 27310657 )
2016
31
Granular cell tumor of the esophagus in an adolescent. ( 28018455 )
2016
32
Granular Cell Tumor on the Chest of a 9-Year-Old Female: Case Report and a Retrospective Analysis. ( 25775653 )
2015
33
Intraorbital Granular Cell Tumor Ophthalmologic and Radiologic Findings. ( 25963156 )
2015
34
Granular cell tumor (GCT) mimicking a nonsecreting anterior pituitary adenoma. ( 26465283 )
2015
35
A case report of a rare intramuscular granular cell tumor. ( 26377191 )
2015
36
Primary cutaneous malignant granular cell tumor: a case report in China and review of the literature. ( 26187381 )
2015
37
Granular cell tumor of the gastrointestinal tract: histologic and immunohistochemical analysis of 98 cases. ( 25882927 )
2015
38
Granular cell tumor of the urethra: a case report and literature review. ( 26643561 )
2015
39
Granular cell tumor of the thyroid: Clinical and pathological characteristics of a rare case in a 14-year-old girl. ( 25624902 )
2015
40
Granular Cell Tumor of Breast: a Case Report and Review of Literature. ( 27065673 )
2015
41
A Case of Mediastinal Granular Cell Tumor with Horner's Syndrome. ( 26041255 )
2015
42
Intraneural granular cell tumor of a cervical dorsal nerve root: a case report and review of the literature. ( 26485410 )
2015
43
Large Mid-Esophageal Granular Cell Tumor: Benign Versus Malignant. ( 26266012 )
2015
44
Granular cell tumors and congenital granular cell epulis in children: Similar entities. ( 25783372 )
2015
45
Malignant granular cell tumor of the breast; literature review. ( 25885145 )
2015
46
Granular cell tumor in the pituitary stalk: a case report. ( 25977911 )
2015
47
WT1 Expression in Adult Granular Cell Tumor of the Vocal Cord and Tongue. ( 26162589 )
2015
48
Congenital granular cell tumor - a rare entity. ( 26034711 )
2015
49
Malignant granular cell tumor of the foot-multimodality imaging findings and literature review. ( 25487437 )
2015
50
From newborn to toddler: report of two cases of congenital granular cell tumor. ( 25579012 )
2015

Variations for Granular Cell Tumor

Cosmic variations for Granular Cell Tumor:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM14452 PTCH1 skin,neck,carcinoma,NS c.2321G>A p.G774E 6
2 COSM29072 PTCH1 skin,neck,carcinoma,NS c.1067+1G>A p.? 6
3 COSM29053 PTCH1 skin,neck,carcinoma,NS c.833G>A p.W278* 6
4 COSM17483 PTCH1 skin,neck,carcinoma,NS c.1729-1G>T p.? 6
5 COSM17468 PTCH1 skin,neck,carcinoma,NS c.584G>T p.R195M 6
6 COSM516 KRAS skin,neck,carcinoma,NS c.34G>T p.G12C 6
7 COSM498 HRAS skin,neck,carcinoma,NS c.182A>T p.Q61L 6

Expression for Granular Cell Tumor

Search GEO for disease gene expression data for Granular Cell Tumor.

Pathways for Granular Cell Tumor

Pathways related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.77 ENO2 GFAP S100B UCHL1
2
Show member pathways
11.37 DES GFAP VIM
3
Show member pathways
10.91 DES VIM
4 10.7 GFAP S100B VIM

GO Terms for Granular Cell Tumor

Cellular components related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 9.26 DES GFAP
2 photoreceptor inner segment GO:0001917 9.16 ENO2 INHA
3 intermediate filament GO:0005882 9.13 DES GFAP VIM
4 neuronal cell body GO:0043025 8.92 ENO2 INHA S100B UCHL1

Biological processes related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 8.96 DES VIM
2 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 9.26 DES GFAP S100B VIM
2 structural constituent of cytoskeleton GO:0005200 8.8 DES GFAP VIM

Sources for Granular Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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