MCID: GRN010
MIFTS: 46

Granular Cell Tumor

Categories: Rare diseases, Cancer diseases

Aliases & Classifications for Granular Cell Tumor

MalaCards integrated aliases for Granular Cell Tumor:

Name: Granular Cell Tumor 12 50 52 42 14 69
Granular Cell Carcinoma 12 14
Giant Granulocellular Abrikosov's Tumor 50
Malignant Variant of Abrikosov's Tumor 50
Abrikosoff's Granulous Cell Tumor 50
Granular Cell Adenocarcinoma 12
Neoplasm of Granular Cell 12
Carcinoma, Granular Cell 69
Granular Cell Tumor Nos 12
Abrikosoff's Tumor 50
Abrikosov’s Tumor 50
Abrikosov's Tumor 69

Classifications:



External Ids:

Disease Ontology 12 DOID:2411 DOID:4903
NCIt 47 C3474 C3681

Summaries for Granular Cell Tumor

NIH Rare Diseases : 50 granular celltumors(gcts) are soft tissue tumors that can occur anywhere in the body. they are thought to arise from the cells that surround and insulate the nerve cells in our body (schwann cells). most granular cell tumors are benign (non-cancerous), although some may be locally aggressive. less than 2% are malignant (cancerous), but these are aggressive and often are associated with a poor prognosis. gcts affect females more often than males and usually present as a solitary painless mass. a few individuals have multiple gcts. in most cases, these tumors are located in the skin of the head and neck, especially inside the mouth (70%), the tongue being the most common site. they may also occur in the breast, heart, pituitary gland, stomach, esophagus, genitalia, and upper respiratory tract. gcts may be  part of some genetic syndromes, such as leopard syndrome and neurofibromatosis. complete surgical removal of the tumor is usually curative, but in some cases the tumors may recur. last updated: 10/25/2016

MalaCards based summary : Granular Cell Tumor, also known as granular cell carcinoma, is related to myoblastoma and malignant granular cell myoblastoma. An important gene associated with Granular Cell Tumor is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Cytoskeleton remodeling Neurofilaments. The drugs Cisplatin and Gemcitabine have been mentioned in the context of this disorder. Affiliated tissues include breast, tongue and skin.

Disease Ontology : 12 A carcinoma that derives from epithelial cells, with polygonal accumulation of secondary lysosomes in the cytoplasm.

Wikipedia : 72 Granular cell tumor is a tumor that can develop on any skin or mucosal surface, but occurs on the tongue... more...

Related Diseases for Granular Cell Tumor

Diseases in the Granular Cell Tumor family:

Congenital Granular Cell Tumor

Diseases related to Granular Cell Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 262)
id Related Disease Score Top Affiliating Genes
1 myoblastoma 32.5 ENO2 UCHL1
2 malignant granular cell myoblastoma 32.0 ENO2 GFAP
3 granular cell leiomyosarcoma 30.1 CD68 DES
4 gastrointestinal stromal tumor 28.6 DES ENO2 S100B UCHL1 VIM
5 congenital granular cell tumor 12.1
6 vulvar granular cell tumor 12.1
7 malignant gastric granular cell tumor 12.0
8 breast granular cell tumor 12.0
9 skin granular cell tumor 12.0
10 neurohypophysis granular cell tumor 11.9
11 congenital epulis 11.3
12 malignant granular cell esophageal tumor 10.9
13 cardiac granular cell neoplasm 10.9
14 mediastinal granular cell myoblastoma 10.9
15 malignant granular cell skin tumor 10.9
16 2q31.1 microdeletion syndrome 10.8 ENO2 VIM
17 skin papilloma 10.7 ENO2 VIM
18 infantile scoliosis 10.7 DES VIM
19 aortic aneurysm 10.7 DES VIM
20 lymphocytic infiltrate of jessner 10.7 DES VIM
21 skin lipoma 10.7 DES VIM
22 mannose-binding lectin protein deficiency 10.7 DES VIM
23 berk-tabatznik syndrome 10.7 DES VIM
24 malignant hyperthermia susceptibility type 3 10.7 DES ENO2
25 cellular ependymoma 10.7 DES VIM
26 ovary rhabdomyosarcoma 10.7 DES ENO2
27 follicular infundibulum tumor 10.7 DES VIM
28 childhood pleomorphic rhabdomyosarcoma 10.7 DES VIM
29 secondary syphilis 10.7 ENO2 VIM
30 sebaceous adenoma 10.6 DES VIM
31 lymphangiosarcoma 10.6 INHA VIM
32 short-rib thoracic dysplasia 12 10.6 DES VIM
33 rectal neoplasm 10.6 DES VIM
34 morbid obesity 10.6 ENO2 INHA
35 extraskeletal mesenchymal chondrosarcoma 10.6 DES VIM
36 immune-mediated encephalomyelitis 10.6 S100B VIM
37 neurogenic thoracic outlet syndrome 10.6 S100B VIM
38 nephrogenic adenoma of urinary bladder 10.6 DES VIM
39 myoepithelial carcinoma 10.6 DES VIM
40 ossifying fibromyxoid tumor 10.6 ENO2 VIM
41 noninvasive malignant thymoma 10.6 S100B VIM
42 pancreatic intraductal papillary-colloid carcinoma 10.6 S100B VIM
43 large cell acanthoma 10.6 DES VIM
44 multiple mitochondrial dysfunctions syndrome 2 10.6 DES VIM
45 lice infestation 10.6 S100B VIM
46 pancreatic ductal carcinoma 10.6 INHA VIM
47 enteric pattern testicular yolk sac tumor 10.6 ENO2 S100B
48 motor neuron disease 10.6 ENO2 S100B
49 spleen cancer 10.6 DES S100B
50 hydromyelia 10.6 ENO2 S100B

Graphical network of the top 20 diseases related to Granular Cell Tumor:



Diseases related to Granular Cell Tumor

Symptoms & Phenotypes for Granular Cell Tumor

Drugs & Therapeutics for Granular Cell Tumor

Drugs for Granular Cell Tumor (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 209)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Cisplatin Approved Phase 4 15663-27-1 84093 441203 2767
2
Gemcitabine Approved Phase 4,Phase 3 95058-81-4 60750
3
Pemetrexed Approved, Investigational Phase 4,Phase 3,Early Phase 1 150399-23-8, 137281-23-3 446556 60843
4
Cyclophosphamide Approved, Investigational Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1 50-18-0, 6055-19-2 2907
5
Epirubicin Approved Phase 4 56420-45-2 41867
6
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2,Early Phase 1 59-30-3 6037
7
leucovorin Approved, Nutraceutical Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1 58-05-9 143 6006
8
Docetaxel Approved May 1996, Investigational Phase 4,Phase 3,Phase 1,Phase 2 114977-28-5 148124 9877265
9 Anti-Infective Agents Phase 4,Phase 3,Phase 2,Phase 1
10 Antimetabolites Phase 4,Phase 2,Phase 3,Phase 1
11 Antimetabolites, Antineoplastic Phase 4,Phase 2,Phase 3,Phase 1
12 Antiviral Agents Phase 4,Phase 3,Phase 2,Phase 1
13 Folic Acid Antagonists Phase 4,Phase 3,Phase 2,Early Phase 1
14 Immunosuppressive Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
15 Nucleic Acid Synthesis Inhibitors Phase 4,Phase 3,Phase 2,Phase 1,Early Phase 1
16 Vitamin B Complex Phase 4,Phase 3,Phase 2,Early Phase 1
17 Alkylating Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
18 Antirheumatic Agents Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
19 Anti-Bacterial Agents Phase 4,Phase 3,Phase 2,Phase 1
20 Antibiotics, Antitubercular Phase 4,Phase 2,Phase 3,Phase 1
21 Topoisomerase Inhibitors Phase 4,Phase 2,Phase 3,Phase 1,Early Phase 1
22 Antimitotic Agents Phase 4,Phase 3
23 Folate Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1
24 Vitamin B9 Nutraceutical Phase 4,Phase 3,Phase 2,Early Phase 1
25
Carboplatin Approved Phase 2, Phase 3,Phase 1 41575-94-4 10339178 498142 38904
26
Amphotericin B Approved, Investigational Phase 3 1397-89-3 14956 5280965
27
Caspofungin Approved Phase 3,Phase 2 179463-17-3, 162808-62-0 468682 2826718
28
Miconazole Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1 22916-47-8 4189
29
Fentanyl Approved, Illicit, Investigational, Vet_approved Phase 3 437-38-7 3345
30
Vinorelbine Approved, Investigational Phase 3 71486-22-1 60780 44424639
31
Darbepoetin alfa Approved, Investigational Phase 3 11096-26-7, 209810-58-2
32
Iron Approved Phase 3 7439-89-6 23925
33
Dalteparin Approved Phase 3 9005-49-6
34
Heparin Approved, Investigational Phase 3 9005-49-6 772 46507594
35
Ondansetron Approved Phase 3 99614-02-5 4595
36
Doxorubicin Approved, Investigational Phase 2, Phase 3,Phase 1 23214-92-8 31703
37
Ifosfamide Approved Phase 2, Phase 3,Phase 1 3778-73-2 3690
38
Mechlorethamine Approved Phase 2, Phase 3,Phase 1 51-75-2 4033
39
Busulfan Approved, Investigational Phase 2, Phase 3,Early Phase 1 55-98-1 2478
40
Etoposide Approved Phase 2, Phase 3,Phase 1,Early Phase 1 33419-42-0 36462
41
Fludarabine Approved Phase 2, Phase 3, Phase 1 21679-14-1, 75607-67-9 30751
42 Thiotepa Approved Phase 2, Phase 3,Phase 1 52-24-4 5453
43
Melphalan Approved Phase 2, Phase 3 148-82-3 4053 460612
44
Ginseng Approved, Nutraceutical Phase 3 50647-08-0
45 Pancreatic Polypeptide Investigational Phase 3 59763-91-6
46
Doxil Approved June 1999 Phase 2, Phase 3,Phase 1 31703
47 Antifungal Agents Phase 3,Phase 2,Phase 1
48 Antiparasitic Agents Phase 3,Phase 1
49 Antiprotozoal Agents Phase 3
50 Echinocandins Phase 3,Phase 2

Interventional clinical trials:

(show top 50) (show all 117)

id Name Status NCT ID Phase Drugs
1 Chemotherapy Combined With Yangzhengxiaoji Capsule in Patients With Advanced Non-Small Cell Lung Cancer Unknown status NCT02195453 Phase 4 Yangzhengxiaoji Capsule;Placebo Capsule
2 Huaier Granule in Treating Women With Triple Negative Breast Cancer Recruiting NCT02615457 Phase 4 Huaier Granule
3 Neoadjuvant Chemotherapy With or Without Huaier Granule in Treating Women With Locally Advanced Breast Cancer That Can Be Removed By Surgery Recruiting NCT02627248 Phase 4 Huaier Granule;Epirubicin;Docetaxel;Cyclophosphamide
4 Caspofungin Acetate Compared With Amphotericin B Liposomal in Treating Patients With Persistent Fever and Neutropenia Following Cancer Treatment Completed NCT00008359 Phase 3 caspofungin acetate;liposomal amphotericin B
5 Fentanyl Sublingual Spray in Treating Patients With Breakthrough Cancer Pain Completed NCT00538850 Phase 3 Fentanyl sublingual spray;Placebo
6 Liposomal Amphotericin B in Treating Granulocytopenia and Persistent Unexplained Fever in Cancer Patients Completed NCT00003938 Phase 3 liposomal amphotericin B
7 Efficacy Study of Integrated TCM Combined With Chemotherapy in Postoperative NSCLC Patients Completed NCT01441752 Phase 3 TCM;placebo
8 Darbepoetin Alfa Compared With Epoetin Alfa in Treating Anemia in Patients Receiving Chemotherapy for Cancer Completed NCT00070382 Phase 3 darbepoetin alfa;epoetin alfa
9 Darbepoetin Alfa With or Without Iron in Treating Anemia Caused By Chemotherapy in Patients With Cancer Completed NCT00661999 Phase 3 sodium ferric gluconate complex in sucrose
10 Dalteparin to Prevent Complications in Cancer Patients Receiving Chemotherapy Through a Catheter Completed NCT00006083 Phase 3 Fragmin
11 Opioid Titration Order Sheet or Standard Care in Treating Patients With Cancer Pain Completed NCT00666211 Phase 3
12 American Ginseng in Treating Patients With Fatigue Caused by Cancer Completed NCT00719563 Phase 3 American ginseng
13 Ondansetron in Treating Patients With Advanced Cancer and Chronic Nausea and Vomiting Not Caused by Cancer Treatment Completed NCT00006348 Phase 3 ondansetron
14 Radiation Therapy With or Without Combination Chemotherapy or Pazopanib Hydrochloride Before Surgery in Treating Patients With Newly Diagnosed Non-rhabdomyosarcoma Soft Tissue Sarcomas That Can Be Removed by Surgery Recruiting NCT02180867 Phase 2, Phase 3 Doxorubicin Hydrochloride;Ifosfamide;Pazopanib Hydrochloride
15 Combination Chemotherapy and Donor Stem Cell Transplant in Treating Patients With Aplastic Anemia or Hematologic Cancer Active, not recruiting NCT00003816 Phase 2, Phase 3 busulfan;carboplatin;cyclophosphamide;etoposide;fludarabine phosphate;melphalan;thiotepa
16 Clinical Study of Chinese Medicine Plus Chemotherapy Maintenance in Advanced Non Small Cell Lung Cancer Enrolling by invitation NCT02900742 Phase 3 YiQiFang;YangYinFang;YiQiYangYinFang;Gemcitabine®;Pemetrexed®;Docetaxel®;placebo granules
17 Efficacy Study of Comprehensive Rehabilitation Program in Postoperative NSCLC Patients Enrolling by invitation NCT03244605 Phase 3 TCM;placebo
18 Songyou Granule and Transarterial Chemoembolization for Hepatocellular Carcinoma Unknown status NCT00805896 Phase 2 Songyou;placebo
19 Cyclosporine in Treating Patients With Low Blood Counts Caused By Hematologic Cancer Completed NCT00031980 Phase 2 cyclosporine
20 Caspofungin Acetate in Treating Aspergillosis in Patients With Hematologic Cancer or in Patients Who Have Undergone a Stem Cell Transplant Completed NCT00110045 Phase 2 caspofungin acetate
21 Donor Umbilical Cord Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies Completed NCT01093586 Phase 2 busulfan;cyclophosphamide;anti-thymocyte globulin;methylprednisolone;cyclosporine;mycophenolate mofetil
22 Doxorubicin Hydrochloride Liposome and Bortezomib in Treating Patients With Refractory Hematologic Cancer or Malignant Solid Tumor or Metastatic Breast Cancer Completed NCT00237627 Phase 1, Phase 2 PS-341;Doxil;Velcade
23 Donor Natural Killer Cells After Donor Stem Cell Transplant in Treating Patients With Advanced Cancer Completed NCT00823524 Phase 1, Phase 2
24 Combination Chemotherapy Followed by Peripheral Stem Cell Transplantation in Treating Patients With Refractory Cancer Completed NCT00003406 Phase 1, Phase 2 carboplatin;docetaxel;ifosfamide
25 Peripheral Stem Cell Transplantation in Treating Patients With Breast Cancer or Hematologic Cancer Completed NCT00006225 Phase 1, Phase 2
26 506U78 in Treating Patients With Chronic Lymphocytic Leukemia That Has Not Responded to Fludarabine or Alkylating Agents Completed NCT00003635 Phase 2 nelarabine
27 Study of Akt Inhibitor MK2206 in Patients With Relapsed Lymphoma Completed NCT01258998 Phase 2 Akt inhibitor MK2206
28 Bone Marrow Transplantation in Treating Patients With Hematologic Cancer Completed NCT00005804 Phase 2 cyclophosphamide
29 Interleukin-2 Plus Interferon Alfa in Treating Adults With Metastatic Cancer Completed NCT00002504 Phase 2
30 Epoetin Alfa in Treating Patients With Anemia Who Are Undergoing Chemotherapy for Cancer Completed NCT00255749 Phase 2
31 Dasatinib for Immune Modulation After Donor Stem Cell Transplant for Hematologic Malignancies Recruiting NCT01643603 Phase 1, Phase 2 Dasatinib
32 Dasatinib for Modulating Immune System After Autologous Stem Cell Transplants for Multiple Myeloma, Non-Hodgkin, or Hodgkin Lymphoma Recruiting NCT01609816 Phase 1, Phase 2 Dasatinib
33 Reduced-Intensity Conditioning Before Donor Stem Cell Transplant in Treating Patients With High-Risk Hematologic Malignancies Recruiting NCT01760655 Phase 2 Fludarabine phosphate;Thiotepa;Cyclophosphamide;Tacrolimus;Mycophenolate mofetil
34 Donor T Cells After Donor Stem Cell Transplant in Treating Patients With Hematologic Malignancies Recruiting NCT01839916 Phase 2
35 A Two-Step Approach to Reduced Intensity Bone Marrow Transplant for Patients With Hematological Malignancies Recruiting NCT01384513 Phase 2 Fludarabine;Busulfan;Cyclophosphamide (CY);Tacrolimus;Mycophenolate mofetil
36 Biological Therapy in Treating Patients at High-Risk or With Lymphoma, Lymphoproliferative Disease, or Malignancies Recruiting NCT00002663 Phase 1, Phase 2
37 Alemtuzumab, Fludarabine Phosphate, and Low-Dose Total Body Irradiation Before Donor Stem Cell Transplantation in Treating Patients With Hematological Malignancies Active, not recruiting NCT00040846 Phase 2 fludarabine phosphate;mycophenolate mofetil;cyclosporine
38 Fludarabine Phosphate, Low-Dose Total-Body Irradiation, and Donor Stem Cell Transplant Followed by Cyclosporine, Mycophenolate Mofetil, Donor Lymphocyte Infusion in Treating Patients With Hematopoietic Cancer Active, not recruiting NCT00006251 Phase 1, Phase 2 fludarabine phosphate;cyclosporine;mycophenolate mofetil
39 Mycophenolate Mofetil and Cyclosporine in Reducing Graft-Versus-Host Disease in Patients With Hematologic Malignancies or Metastatic Kidney Cancer Undergoing Donor Stem Cell Transplant Active, not recruiting NCT00078858 Phase 1, Phase 2 fludarabine phosphate;cyclosporine;mycophenolate mofetil
40 Fludarabine Phosphate, Melphalan, and Low-Dose Total-Body Irradiation Followed by Donor Peripheral Blood Stem Cell Transplant in Treating Patients With Hematologic Malignancies Active, not recruiting NCT01529827 Phase 2 fludarabine phosphate;melphalan;tacrolimus;mycophenolate mofetil;methotrexate
41 Fludarabine Phosphate, Radiation Therapy, and Rituximab in Treating Patients Who Are Undergoing Donor Stem Cell Transplant Followed by Rituximab for High-Risk Chronic Lymphocytic Leukemia or Small Lymphocytic Lymphoma Active, not recruiting NCT00104858 Phase 2 Cyclosporine;Fludarabine Phosphate;Mycophenolate Mofetil
42 QUILT-3.009: Study of aNK Infusions in Combination With ALT-803 in Patients With Stage III (IIIB) or Stage (IV) Merkel Cell Carcinoma (MCC) Active, not recruiting NCT02465957 Phase 2
43 Alemtuzumab in Myelodysplastic Syndrome (MDS), Aplastic Anemia, and T-Cell Large Granular Lymphocytic Leukemia (T-GL) Terminated NCT01191749 Phase 2 Alemtuzumab
44 Methotrexate Followed by Fludarabine in Patients With T-Cell Large Granular Lymphocytic Leukemia Terminated NCT00278265 Phase 2 MTX followed by fludarabine
45 Tipifarnib in Treating Patients With Anemia or Neutropenia and Large Granular Lymphocyte Leukemia Terminated NCT00360776 Phase 2 tipifarnib
46 Effect of Cyclosporine Therapy on Gene Expression in Patients With Large Granular Lymphocyte Leukemia Terminated NCT00363779 Phase 2 Cyclosporine
47 Lenalidomide With or Without Rituximab in Treating Patients With Progressive or Relapsed Chronic Lymphocytic Leukemia, Small Lymphocytic Lymphoma, Prolymphocytic Leukemia, or Non-Hodgkin Lymphoma Previously Treated With Donor Stem Cell Transplant Terminated NCT01419795 Phase 2 lenalidomide
48 Methotrexate With or Without Cyclophosphamide in Treating Patients With Lymphocytic Leukemia Terminated NCT00003910 Phase 2 Cyclophosphamide;Methotrexate;Prednisone
49 Sirolimus, Tacrolimus, Thymoglobulin and Rituximab as Graft-versus-Host-Disease Prophylaxis in Patients Undergoing Haploidentical and HLA Partially Matched Donor Hematopoietic Cell Transplantation Terminated NCT01116232 Phase 2 sirolimus;tacrolimus
50 Ipilimumab and Local Radiation Therapy in Treating Patients With Recurrent Melanoma, Non-Hodgkin Lymphoma, Colon, or Rectal Cancer Terminated NCT01769222 Phase 1, Phase 2

Search NIH Clinical Center for Granular Cell Tumor

Cochrane evidence based reviews: granular cell tumor

Genetic Tests for Granular Cell Tumor

Anatomical Context for Granular Cell Tumor

MalaCards organs/tissues related to Granular Cell Tumor:

39
Breast, Tongue, Skin, T Cells, Pituitary, Bone, Lung

Publications for Granular Cell Tumor

Articles related to Granular Cell Tumor:

(show top 50) (show all 666)
id Title Authors Year
1
Pleural-based granular cell tumor. ( 28670071 )
2017
2
A Case of Granular Cell Tumor of the Clitoris in a Postmenopausal Woman. ( 28951863 )
2017
3
Granular cell tumor of the orbit: pathological features and treatment. ( 28417615 )
2017
4
Intraorbital Granular Cell Tumor Involving in Medial Rectus and Optic Nerve. ( 28639585 )
2017
5
Extra-tongue oral granular cell tumor: Histological and immunohistochemical aspect. ( 27918739 )
2017
6
Non-neural granular cell tumor of the uterine corpus mimicking uterine leiomyoma: A case report. ( 28781812 )
2017
7
Granular cell tumor mimicking a squamous cell carcinoma of the tongue: a case report. ( 28057062 )
2017
8
Eosinophilic Esophagitis and Esophageal Granular Cell Tumor: An Unexpected Association. ( 28296675 )
2017
9
Coexistent Squamous Cell Carcinoma and Granular Cell Tumor of Head and Neck Region: Report of Two Very Rare Cases and Review of the Literature. ( 28783989 )
2017
10
Sellar and Suprasellar Granular Cell Tumor of Neurohypophysis. ( 28303860 )
2017
11
A case of symptomatic granular cell tumor of the sellar region with large calcification. ( 28276095 )
2017
12
Granular cell tumor at an unusual site masquerading as a neurofibroma. ( 28879925 )
2017
13
Unexpected Presentation of Perianal Granular Cell Tumor in a Young Woman. ( 28284459 )
2017
14
Lung Metastases from Esophageal Granular Cell Tumor: An Undoubted Criterion for Malignancy. ( 28506712 )
2017
15
Extent of surgical resection and tumor size predicts prognosis in granular cell tumor of the sellar region. ( 28948361 )
2017
16
Congenital Gingival Granular Cell Tumor: A Case Report. ( 28293667 )
2017
17
Granular cell tumor of the esophagus. ( 28366624 )
2017
18
Granular cell tumor of the urinary bladder. ( 28861316 )
2017
19
Granular cell tumor in breast: a case report. ( 28442932 )
2017
20
Noonan syndrome with multiple lentigines with PTPN11 (T468M) gene mutation accompanied with solitary granular cell tumor. ( 28681392 )
2017
21
Granular Cell Tumor of the Neurohypophysis With TFE-3 Expression: A Rare Case Report. ( 28612665 )
2017
22
A rare case of perianal granular cell tumor: case report and literature review. ( 28603602 )
2017
23
Granular cell tumor in male breast masquerading as atypical apocrine neoplasm: A potential diagnostic pitfall in fine needle aspiration cytology. ( 27016396 )
2016
24
Granular cell tumor in two oral anatomic sites. ( 27007285 )
2016
25
Granular cell tumor presenting in the scrotum of a pediatric patient: a case report and review of the literature. ( 27259474 )
2016
26
Granular Cell Tumor of the Bladder: A Rare Neoplasm Managed With Robotic Partial Cystectomy Using Near-infrared Filter Guidance. ( 27894977 )
2016
27
Erratum: LEOPARD syndrome and multiple granular cell tumors: An underreported association? ( 26924415 )
2016
28
Metachronous Occurrence of Granular Cell Tumor in Breast Skin and Scalp: Diagnostic Challenging Differentiating Benign from Malignant and a Literature Review. ( 26881167 )
2016
29
Computed tomography and magnetic resonance imaging findings of intraorbital granular cell tumor (Abrikossoff's tumor): a case report. ( 27176551 )
2016
30
Granular cell tumor in a child: An uncommon cutaneous presentation. ( 27730035 )
2016
31
A Rare Case of a Primary Cutaneous Desmoplastic Atypical Granular Cell Tumor. ( 27759691 )
2016
32
Atypical granular cell tumor in the maxilla: The first report of primary intraosseous granular cell tumor. ( 27310657 )
2016
33
Unusual Granular Cell Tumor of the Trachea Coexisting With Papillary Thyroid Carcinoma and Masquerading as Tracheal Invasion of Recurred Thyroid Carcinoma: A Case Report. ( 27149467 )
2016
34
Synchronous existence of granular cell tumor and small cell carcinoma of lung: An unusual entity. ( 26960647 )
2016
35
Abrikossoff's tumor mimicking endometrial tumor--literature review and case report of the first described granular cell tumor in scar tissue after caesarean section. ( 27172759 )
2016
36
Granular Cell Tumor of the Common Hepatic Duct as an Unusual Cause of Jaundice in a Hepatitis C Patient. ( 26958564 )
2016
37
Granular cell tumor of the esophagus in an adolescent. ( 28018455 )
2016
38
Granular Cell Tumor Within an Ovarian Mature Cystic Teratoma: Report of a Unique Case and Review of the Literature. ( 27750257 )
2016
39
Granular cell tumor of cecum. ( 27324518 )
2016
40
Suprasellar granular cell tumor of the neurohypophysis: surgical outcome of a very rare tumor. ( 26753850 )
2016
41
Endoscopic resection of rectal granular-cell tumor using elastic band ligation. ( 26864296 )
2016
42
Benign Granular Cell Tumor of Breast. ( 27124422 )
2016
43
Congenital granular cell tumor in a child with tetralogy of Fallot. ( 27434473 )
2016
44
S-100 Negative Granular Cell Tumor (So-called Primitive Polypoid Non-neural Granular Cell Tumor) of the Oral Cavity. ( 27709427 )
2016
45
A rare laryngeal tumor in a patient with thyroid papillary cancer: granular cell tumor. ( 27068886 )
2016
46
Esophageal Granular Cell Tumor: A Benign Tumor or an Insidious Cause for Concern? ( 27999519 )
2016
47
Fine-needle aspiration cytology of cutaneous granular cell tumor: Report of two cases with special emphasis on cytological differential diagnosis. ( 27011439 )
2016
48
Esophageal Granular Cell Tumor: A Case Report and Review of Literature. ( 27752408 )
2016
49
Vulvar granular cell tumor. ( 27510686 )
2016
50
Slowly Growing Nodule on the Trunk: Cutaneous Granular Cell Tumor. ( 27504442 )
2016

Variations for Granular Cell Tumor

Cosmic variations for Granular Cell Tumor:

9
id Cosmic Mut ID Gene Symbol COSMIC Disease Classification
(Primary site, Site subtype, Primary histology, Histology subtype)
Mutation CDS Mutation AA Conf
1 COSM17483 PTCH1 skin,neck,carcinoma,NS c.1729-1G>T p.? 5
2 COSM17468 PTCH1 skin,neck,carcinoma,NS c.584G>T p.R195M 5
3 COSM29053 PTCH1 skin,neck,carcinoma,NS c.833G>A p.W278* 5
4 COSM29072 PTCH1 skin,neck,carcinoma,NS c.1067+1G>A p.? 5
5 COSM14452 PTCH1 skin,neck,carcinoma,NS c.2321G>A p.G774E 5
6 COSM516 KRAS skin,neck,carcinoma,NS c.34G>T p.G12C 5
7 COSM498 HRAS skin,neck,carcinoma,NS c.182A>T p.Q61L 5

Expression for Granular Cell Tumor

Search GEO for disease gene expression data for Granular Cell Tumor.

Pathways for Granular Cell Tumor

Pathways related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.77 ENO2 GFAP S100B UCHL1
2
Show member pathways
11.37 DES GFAP VIM
3
Show member pathways
10.91 DES VIM
4 10.7 GFAP S100B VIM

GO Terms for Granular Cell Tumor

Cellular components related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 intermediate filament cytoskeleton GO:0045111 8.96 DES GFAP
2 intermediate filament GO:0005882 8.8 DES GFAP VIM

Biological processes related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 muscle filament sliding GO:0030049 9.32 DES VIM
2 long-term synaptic potentiation GO:0060291 9.07 S100B
3 astrocyte development GO:0014002 8.96 VIM
4 Bergmann glial cell differentiation GO:0060020 8.85 VIM
5 intermediate filament-based process GO:0045103 8.65 VIM
6 intermediate filament organization GO:0045109 8.62 DES VIM

Molecular functions related to Granular Cell Tumor according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural constituent of cytoskeleton GO:0005200 8.8 DES GFAP VIM

Sources for Granular Cell Tumor

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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