MCID: GRN003
MIFTS: 34

Granulomatous Dermatitis malady

Category: Skin diseases

Aliases & Classifications for Granulomatous Dermatitis

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Aliases & Descriptions for Granulomatous Dermatitis:

Name: Granulomatous Dermatitis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:4397
NCIt42 C3505
UMLS65 C0743086

Summaries for Granulomatous Dermatitis

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MalaCards based summary: Granulomatous Dermatitis is related to interstitial granulomatous dermatitis with arthritis and posterior valve urethra. An important gene associated with Granulomatous Dermatitis is ACE (Angiotensin I Converting Enzyme), and among its related pathways are Adipocytokine signaling pathway and Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway. Affiliated tissues include lung, skin and breast, and related mouse phenotypes are endocrine/exocrine gland and liver/biliary system.

Related Diseases for Granulomatous Dermatitis

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Diseases related to Granulomatous Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 173)
idRelated DiseaseScoreTop Affiliating Genes
1interstitial granulomatous dermatitis with arthritis12.5
2posterior valve urethra10.2ACE, TNF
3ischemic optic neuropathy10.2ACE, TNF
4congenital nasal pyriform aperture stenosis with holoprosencephaly10.2ACE, TNF
5brain stem glioma10.2TNF, TNFRSF1B
6meige syndrome10.2ACE, TNF
7telangiectasis10.2TNF, TNFRSF1B
8acneiform dermatitis10.2TNF, TNFRSF1B
9gonococcal bursitis10.2TNF, TNFRSF1B
10byssinosis10.2ACE, TNF
11precursor b lymphoblastic lymphoma/leukemia10.2TNF, TNFRSF1B
12membranous glomerulonephritis10.2TNF, TNFRSF1B
13fetal erythroblastosis10.2ACE, TNF
14ciliary dyskinesia, primary, 1510.2TNF, TNFRSF1B
15artery disease10.2ACE, TNF
16cogan-reese syndrome10.2TNF, TNFRSF1B
17endometrial stromal sarcoma10.2TNF, TNFRSF1B
18pyosalpinx10.1TNF, TNFRSF1B
19renal oncocytoma10.1ACE, TNF
20single ventricular heart10.1ACE, TNF
21kernicterus due to isoimmunization10.1TNF, TNFRSF1B
22periampullary adenoma10.1ACE, TNF
23blue color blindness10.1TNF, TNFRSF1B
24obstructive sleep apnea10.1ACE, TNF
25viral laryngitis10.1TNF, TNFRSF1B
26epidermolysis bullosa dystrophica10.1ACE, TNF
27breast cancer10.1
28adenocarcinoma10.1
29pancreatitis10.1
30rectal disease10.1TNF, TNFRSF1B
31chronic venous insufficiency10.1ACE, TNF
32frontal encephalocele10.1FOXC1, TNF
33hyperglycemia10.1ACE, TNF
34glycoproteinosis10.1TNF, TNFRSF1B
35tertiary syphilis10.1ACE, TNF
36organic acidemia10.1ACE, TNF
37lung lymphoma10.1TNF, TNFRSF1B
38aspergillosis10.0
39atherosclerosis10.0
40fibrosarcoma10.0
41retinitis10.0
42pneumonia10.0
43endotheliitis10.0
44hemifacial spasm10.0ACE, TNF
45gastroduodenal crohn's disease10.0NOD2, TNF
46hidradenitis10.0NOD2, TNF
47capillary lymphangioma10.0NOD2, TNF
48spondylocamptodactyly10.0NOD2, TNF
49vallecula cancer10.0NOD2, TNF
50ileocolitis10.0NOD2, TNF

Graphical network of the top 20 diseases related to Granulomatous Dermatitis:



Diseases related to granulomatous dermatitis

Symptoms for Granulomatous Dermatitis

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Drugs & Therapeutics for Granulomatous Dermatitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Granulomatous Dermatitis

Genetic Tests for Granulomatous Dermatitis

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Anatomical Context for Granulomatous Dermatitis

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MalaCards organs/tissues related to Granulomatous Dermatitis:

33
Lung, Skin, Breast, Liver, Heart, Smooth muscle, Brain

Animal Models for Granulomatous Dermatitis or affiliated genes

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MGI Mouse Phenotypes related to Granulomatous Dermatitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.7ACE, FOXC1, TNF, TNFRSF1B
2MP:00053708.7ACE, FOXC1, TNF, TNFRSF1B
3MP:00053818.2FOXC1, NOD2, TNF, TNFRSF1B
4MP:00053907.9FOXC1, NOD2, TNF, TNFRSF1B
5MP:00053767.7ACE, FOXC1, NOD2, TNF, TNFRSF1B
6MP:00053787.5ACE, FOXC1, NOD2, TNF, TNFRSF1B

Publications for Granulomatous Dermatitis

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Articles related to Granulomatous Dermatitis:

(show top 50)    (show all 152)
idTitleAuthorsYear
1
Cardiolipin metabolism and its causal role in the etiology of the inherited cardiomyopathy Barth syndrome. (26415690)
2015
2
Anatomical patterns of dermatitis in adult filaggrin mutation carriers. (25659224)
2015
3
Acquired JAK-2 V617F Mutational Analysis in Pakistani Patients with Essential Thrombocythemia. (26514532)
2015
4
Natural progression of a sporadic pheochromocytoma over 15A years. (25257240)
2014
5
Amaryllidaceae alkaloids inhibit nuclear-to-cytoplasmic export of ribonucleoprotein (RNP) complex of highly pathogenic avian influenza virus H5N1. (23136954)
2013
6
Prenatal smoke exposure: effects on infant auditory system and placental gene expression. (23665419)
2013
7
Hydantoin based inhibitors of MMP13--discovery of AZD6605. (23810497)
2013
8
A novel treatment regimen for Duchenne muscular dystrophy. (24045777)
2013
9
Interleukin-4 modulates the inflammatory response in ifosfamide-induced hemorrhagic cystitis. (21468627)
2012
10
Celiac disease prevalence in children and adolescents with myocarditis and dilated cardiomiopathy. (23093320)
2012
11
The impact of severity of parental myopia on myopia in Chinese children. (22544002)
2012
12
Acute intestinal obstruction: a rare aetiology. (22792504)
2012
13
Cystic lymphangioma of the pancreas mimicking pancreatic pseudocyst. (22066085)
2011
14
Inherited and acquired factor V deficiency. (21245750)
2011
15
Efficacy and safety of sorafenib in a subset of patients with advanced soft tissue sarcoma from a Phase II randomized discontinuation trial. (20016927)
2011
16
Pleural malignant mesothelioma with osteoclast-like giant cells. (20403048)
2010
17
A domesticated transposon mediates the effects of a single-nucleotide polymorphism responsible for enhanced muscle growth. (20134481)
2010
18
Accessory mitral valve causing left ventricular outflow tract obstruction. (20719735)
2010
19
Use of anabolic-androgenic steroids masking the diagnosis of pleural tuberculosis: a case report. (19175931)
2009
20
Mutations in the Arabidopsis peroxisomal ABC transporter COMATOSE allow differentiation between multiple functions in planta: insights from an allelic series. (19019987)
2009
21
MicroRNA-7, a homeobox D10 target, inhibits p21-activated kinase 1 and regulates its functions. (18922890)
2008
22
Idiopathic Tolosa-Hunt syndrome: four additional cases. (18763481)
2008
23
Continuous treatment of bestatin induces anti-angiogenic property in endothelial cells. (17270026)
2007
24
Current management of renal anemia in patients with chronic kidney disease at the predialysis stage]. (17695813)
2007
25
Oral and maxillofacial manifestations of familial adenomatous polyposis. (17577321)
2007
26
The Na+:Cl- cotransporter is activated and phosphorylated at the amino-terminal domain upon intracellular chloride depletion. (16887815)
2006
27
Effect of neuronal nitric oxide synthase inhibition on caspase-9 activity during hypoxia in the cerebral cortex of newborn piglets. (16545906)
2006
28
The prevalence of PIK3CA mutations in gastric and colon cancer. (15994075)
2005
29
Lack of herpes virus DNA in choroidal tissues of a patient with serpiginous choroiditis. (15522374)
2004
30
SRA coactivation of estrogen receptor-alpha is phosphorylation- independent, and enhances 4-hydroxytamoxifen agonist activity. (15351741)
2004
31
Identification of a novel family of G protein-coupled receptor associated sorting proteins. (15086532)
2004
32
Cytochrome c release is required for phosphatidylserine peroxidation during Fas-triggered apoptosis in lung epithelial A549 cells. (15726829)
2004
33
Binding of alpha5 monoclonal antibody to cell surface alpha5beta1 integrin modulates MMP-2 and MMP-7 activity in B16F10 melanoma cells. (14529092)
2003
34
Divergent abnormal muscle relaxation by hypertrophic cardiomyopathy and nemaline myopathy mutant tropomyosins. (12006676)
2002
35
Pharmacological profile of the novel mammalian tachykinin, hemokinin 1. (11786503)
2002
36
Type I gamma phosphatidylinositol phosphate kinase targets and regulates focal adhesions. (12422220)
2002
37
Expression of multidrug resistance protein and messenger RNA correlate with (99m)Tc-MIBI imaging in patients with lung cancer. (11585860)
2001
38
Arrestin specificity for G protein-coupled receptors in human airway smooth muscle. (11418617)
2001
39
Biological function of a novel gene overexpressed in human hepatocellular carcinoma. (11775832)
2000
40
The nucleotide sequence of a new DMB allele, DMB*0106. (10885572)
2000
41
Prosthetic knee septic arthritis due to Pseudomonas stutzeri. (18159309)
2000
42
Thyroid hormone promotes the phosphorylation of STAT3 and potentiates the action of epidermal growth factor in cultured cells. (10024519)
1999
43
Misdiagnosis of ruptured aortic aneurysm in diverticular disease. (9845136)
1998
44
Assessment of proliferative activity using the MIB1 antibody help to distinguish polymorphous low grade adenocarcinoma from adenoid cystic carcinoma of salivary glands. (9505262)
1997
45
Antioxidants inhibit the expression of intercellular cell adhesion molecule-1 and vascular cell adhesion molecule-1 induced by oxidized LDL on human umbilical vein endothelial cells. (8958136)
1997
46
Insulin, insulin-like growth factor-binding protein-1, and sex hormone-binding globulin in patients with Turner's syndrome: course over age in untreated patients and effect of therapy with growth hormone alone and in combination with oxandrolone. (8636264)
1996
47
Generalized lymphangiomatosis and chylothorax in the pediatric age group. (1437350)
1992
48
Histamine synthesis and catabolism in various tissues in diabetic rats. (2377078)
1990
49
Growth modulation effects of synthetic steroids on rat prostatic adenocarcinoma and human breast adenocarcinoma cells in vitro. (2357267)
1990
50
Exhibitionism: the essential psychical conflict in manifest dream content. (3421379)
1988

Variations for Granulomatous Dermatitis

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Expression for genes affiliated with Granulomatous Dermatitis

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Search GEO for disease gene expression data for Granulomatous Dermatitis.

Pathways for genes affiliated with Granulomatous Dermatitis

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GO Terms for genes affiliated with Granulomatous Dermatitis

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Biological processes related to Granulomatous Dermatitis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1blood vessel remodelingGO:00019749.9ACE, FOXC1
2apoptotic signaling pathwayGO:00971909.8TNF, TNFRSF1B
3intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.7TNF, TNFRSF1B
4extrinsic apoptotic signaling pathwayGO:00971919.6TNF, TNFRSF1B
5activation of MAPK activityGO:00001879.5NOD2, TNF
6regulation of cell proliferationGO:00421279.4TNF, TNFRSF1B
7defense responseGO:00069529.3NOD2, TNF
8positive regulation of NF-kappaB transcription factor activityGO:00510929.2NOD2, TNF
9defense response to bacteriumGO:00427429.1NOD2, TNF
10positive regulation of transcription from RNA polymerase II promoterGO:00459448.2FOXC1, NOD2, TNF

Sources for Granulomatous Dermatitis

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2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet