MCID: GRN003
MIFTS: 32

Granulomatous Dermatitis malady

Summaries for Granulomatous Dermatitis

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Granulomatous Dermatitis is related to dermatitis and rheumatoid arthritis. An important gene associated with Granulomatous Dermatitis is NOD2 (nucleotide-binding oligomerization domain containing 2), and among its related pathways are Toll-Like receptor Signaling Pathways and Leishmaniasis. The compounds prednisolone and il 10 have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and t cells.

Aliases & Classifications for Granulomatous Dermatitis

About this section
Sources:
8Disease Ontology, 60UMLS, 39NCIt
See all sources

Aliases & Descriptions:

granulomatous dermatitis 8 60


External Ids:

Disease Ontology8 DOID:4397
NCIt39 C3505

Related Diseases for Granulomatous Dermatitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Granulomatous Dermatitis:



Diseases related to granulomatous dermatitis

Clinical Features for Granulomatous Dermatitis

About this section

Drugs & Therapeutics for Granulomatous Dermatitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Granulomatous Dermatitis

Drug clinical trials:

Search ClinicalTrials for Granulomatous Dermatitis

Search NIH Clinical Center for Granulomatous Dermatitis

Search CenterWatch for Granulomatous Dermatitis

Genetic Tests for Granulomatous Dermatitis

About this section

Anatomical Context for Granulomatous Dermatitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Granulomatous Dermatitis:

32
Skin, Thyroid, T cells

Animal Models for Granulomatous Dermatitis or affiliated genes

About this section

Publications for Granulomatous Dermatitis

About this section
Sources:
50PubMed
See all sources

Articles related to Granulomatous Dermatitis:

(show top 50)    (show all 136)
idTitleAuthorsYear
1
A palpable erythematous cord over the trunk in a patient with systemic lupus erythematosus. Interstitial granulomatous dermatitis (IGD). (23677093)
2013
2
Combination therapy with intralesional triamcinolone and oral dapsone for management of palisaded neutrophilic and granulomatous dermatitis. (23473287)
2013
3
A cutaneous interstitial granulomatous dermatitis-like eruption arising in myelodysplasia with leukemic progression. (23221468)
2013
4
Interstitial granulomatous dermatitis with arthritis presenting with the rope sign. (23531209)
2013
5
Granulomatous pigmented purpuric dermatitis associated with primary SjAPgren's syndrome. (22717995)
2013
6
Palisaded neutrophilic and granulomatous dermatitis in a rheumatoid arthritis patient after treatment with adalimumab. (24201093)
2013
7
Palisaded neutrophilic and granulomatous dermatitis associated with ankylosing spondylitis. (23974221)
2013
8
Pseudogranulomatous Spitz nevus: a variant of Spitz nevus with heavy inflammatory infiltrate mimicking a granulomatous dermatitis. (22985334)
2013
9
Case for diagnosis: childhood granulomatous periorificial dermatitis. (24068149)
2013
10
Lupus attributable to anti-TNF therapy and revealed by interstitial granulomatous dermatitis. (21800115)
2012
11
Intravenous immunoglobulins as a treatment of interstitial granulomatous dermatitis with arthritis. (22283232)
2012
12
Deep granulomatous dermatitis of the fin caused by Fusarium solani in a false killer whale (Pseudorca crassidens). (22214860)
2012
13
Cutaneous leishmaniasis with histopathologic pattern of non-necrotizing granulomatous dermatitis in patients treated with adalimumab. (23031374)
2012
14
Autoimmunity-related granulomatous dermatitis in association with hepatitis. (22649335)
2012
15
Interstitial granulomatous dermatitis associated with chronic inflammatory demyelinating polyneuropathy. (22908730)
2012
16
Interstitial granulomatous dermatitis with arthritis responding to tocilizumab. (22250229)
2012
17
Interstitial granulomatous dermatitis? An unusual presentation in the mucosa and periungual skin. (21352283)
2011
18
Palisaded neutrophilic and granulomatous dermatitis in association with sarcoidosis. (20528967)
2011
19
Palisaded neutrophilic granulomatous dermatitis without a definable underlying disorder treated with dapsone. (21839310)
2011
20
Palisaded neutrophilic granulomatous dermatitis caused by cellulitis in a patient with systemic lupus erythematosus. (22098012)
2011
21
Use of ciclosporin in a dog with canine juvenile sterile granulomatous dermatitis and lymphadenitis. (21251099)
2011
22
Granulomatous dermatitis due to Malassezia sympodialis. (21877990)
2011
23
Sporadic Blau syndrome with onset of widespread granulomatous dermatitis in the newborn period. (20199415)
2010
24
Interstitial granulomatous dermatitis in a patient with rheumatoid arthritis on etanercept. (19271571)
2009
25
Granulomatous periorificial dermatitis: a variant of granulomatous rosacea in children? (19298782)
2009
26
Drug-induced hypersensitivity syndrome with superficial granulomatous dermatitis--a novel finding. (19590408)
2009
27
Palisaded neutrophilic granulomatous dermatitis associated with systemic lupus erythematosus presenting with the burning rope sign. (19577332)
2009
28
Interstitial granulomatous dermatitis: a misdiagnosed cutaneous form of systemic lupus erythematosus? (18681887)
2008
29
Interstitial granulomatous dermatitis associated with darifenacin. (19112808)
2008
30
Interstitial granulomatous dermatitis secondary to acute promyelocytic leukemia. (18360133)
2008
31
Interstitial granulomatous dermatitis. (18627754)
2008
32
Early lesion of palisaded neutrophilic granulomatous dermatitis in ulcerative colitis. (17483043)
2007
33
Lichenoid and granulomatous dermatitis associated with atypical mycobacterium infections. (16872476)
2006
34
Interstitial granulomatous dermatitis with arthritis (Ackerman syndrome). (16755676)
2006
35
Equine herpesvirus 2-associated granulomatous dermatitis in a horse. (16846998)
2006
36
Palisaded neutrophilic and granulomatous dermatitis: an unusual cutaneous manifestation of immune-mediated disorders. (15609265)
2004
37
Interstitial granulomatous dermatitis with plaques and arthritis. (14579165)
2003
38
Granulomatous dermatitis in a spadefoot toad (Scaphiopus holbrooki). (12189601)
2002
39
Palisaded neutrophilic granulomatous dermatitis in rheumatoid arthritis. (12140472)
2002
40
Interstitial granulomatous dermatitis with cutaneous cords and arthritis: a disorder associated with autoantibodies. (11464193)
2001
41
Interstitial granulomatous dermatitis with plaques. (10446771)
1999
42
Haematological, serum biochemical and serological features of platypuses with and without mycotic granulomatous dermatitis. (10685184)
1999
43
Sarcoidal foreign-body granulomatous dermatitis associated with ophthalmic drops. (9557788)
1998
44
A case of granulomatous dermatitis: cutaneous leishmaniasis. (9423232)
1997
45
The histopathologic spectrum of palisaded neutrophilic and granulomatous dermatitis in patients with collagen vascular disease. (7944509)
1994
46
Granulomatous dermatitis and Zyderm. (8016250)
1994
47
Recurrent granulomatous dermatitis with eosinophilia. Wells' syndrome. (6724778)
1984
48
Primary granulomatous dermatitis caused by Rhodochrous. Evidence for a pathogenic role in humans. (6651316)
1983
49
Granulomatous dermatitis in carnivores associated with dermatophyte infection. (7397614)
1980
50
Lymphomatoid granulomatosis preceded by chronic granulomatous dermatitis. (718200)
1978

Genetic Variations for Granulomatous Dermatitis

About this section

Expression for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Granulomatous Dermatitis

Search GEO for disease gene expression data for Granulomatous Dermatitis.

Pathways for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
52R&D Systems, 29KEGG, 37NCBI BioSystems Database, 53Reactome
See all sources

Compounds for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 49PharmGKB, 24HMDB
See all sources

Compounds related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1prednisolone44 28 1111.6NOD2
2il 10449.4NOD2, TNF
3infliximab44 49 1111.4NOD2, TNF
4peptidoglycan44 2810.3NOD2, TNF
5prostacyclin449.1ACE, TNF
6nitric oxide44 11 2410.4TNF, NOD2, ACE

GO Terms for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1ACE, TNF

Biological processes related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.6NOD2, TNF
2negative regulation of growth of symbiont in hostGO:0441309.5NOD2, TNF
3defense response to Gram-positive bacteriumGO:0508309.5TNF, NOD2
4positive regulation of interleukin-6 productionGO:0327559.5NOD2, TNF
5positive regulation of JNK cascadeGO:0463309.4NOD2, TNF
6JNK cascadeGO:0072549.4TNF, NOD2
7activation of MAPK activityGO:0001879.3NOD2, TNF
8positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431239.3NOD2, TNF
9positive regulation of ERK1 and ERK2 cascadeGO:0703749.2NOD2, TNF
10positive regulation of NF-kappaB transcription factor activityGO:0510929.0NOD2, TNF

Products for genes affiliated with Granulomatous Dermatitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Granulomatous Dermatitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet