MCID: GRN003
MIFTS: 36

Granulomatous Dermatitis malady

Category: Skin diseases

Aliases & Classifications for Granulomatous Dermatitis

About this section

Aliases & Descriptions for Granulomatous Dermatitis:

Name: Granulomatous Dermatitis 10 12 65

Classifications:



External Ids:

Disease Ontology10 DOID:4397
NCIt42 C3505
UMLS65 C0743086

Summaries for Granulomatous Dermatitis

About this section
MalaCards based summary: Granulomatous Dermatitis is related to cutaneous leishmaniasis and interstitial granulomatous dermatitis with arthritis. An important gene associated with Granulomatous Dermatitis is ACE (Angiotensin I Converting Enzyme), and among its related pathways are Adipocytokine signaling pathway and Apoptosis and survival Anti-apoptotic TNFs/NF-kB/Bcl-2 pathway. Affiliated tissues include neutrophil, lung and skin, and related mouse phenotypes are endocrine/exocrine gland and liver/biliary system.

Related Diseases for Granulomatous Dermatitis

About this section

Diseases related to Granulomatous Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 122)
idRelated DiseaseScoreTop Affiliating Genes
1cutaneous leishmaniasis29.1NOD2, TNF, TNFRSF1B
2interstitial granulomatous dermatitis with arthritis12.2
3dermatitis10.8
4arthritis10.4
5posterior valve urethra10.3ACE, TNF
6ischemic optic neuropathy10.3ACE, TNF
7congenital nasal pyriform aperture stenosis with holoprosencephaly10.3ACE, TNF
8brain stem glioma10.3TNF, TNFRSF1B
9meige syndrome10.3ACE, TNF
10telangiectasis10.3TNF, TNFRSF1B
11acneiform dermatitis10.3TNF, TNFRSF1B
12gonococcal bursitis10.3TNF, TNFRSF1B
13byssinosis10.3ACE, TNF
14precursor b lymphoblastic lymphoma/leukemia10.3TNF, TNFRSF1B
15membranous glomerulonephritis10.3TNF, TNFRSF1B
16fetal erythroblastosis10.2ACE, TNF
17ciliary dyskinesia, primary, 1510.2TNF, TNFRSF1B
18artery disease10.2ACE, TNF
19cogan-reese syndrome10.2TNF, TNFRSF1B
20endometrial stromal sarcoma10.2TNF, TNFRSF1B
21pyosalpinx10.2TNF, TNFRSF1B
22renal oncocytoma10.2ACE, TNF
23single ventricular heart10.2ACE, TNF
24kernicterus due to isoimmunization10.2TNF, TNFRSF1B
25periampullary adenoma10.2ACE, TNF
26blue color blindness10.2TNF, TNFRSF1B
27obstructive sleep apnea10.2ACE, TNF
28viral laryngitis10.2TNF, TNFRSF1B
29epidermolysis bullosa dystrophica10.2ACE, TNF
30rectal disease10.2TNF, TNFRSF1B
31chronic venous insufficiency10.1ACE, TNF
32frontal encephalocele10.1FOXC1, TNF
33hyperglycemia10.1ACE, TNF
34rheumatoid arthritis10.1
35lupus erythematosus10.1
36glycoproteinosis10.1TNF, TNFRSF1B
37tertiary syphilis10.1ACE, TNF
38organic acidemia10.1ACE, TNF
39systemic lupus erythematosus10.1
40lung lymphoma10.1TNF, TNFRSF1B
41hemifacial spasm10.0ACE, TNF
42eosinophilia10.0
43gastroduodenal crohn's disease10.0NOD2, TNF
44hidradenitis10.0NOD2, TNF
45capillary lymphangioma10.0NOD2, TNF
46spondylocamptodactyly10.0NOD2, TNF
47vallecula cancer9.9NOD2, TNF
48ileocolitis9.9NOD2, TNF
49trench fever9.9NOD2, TNF
50myelodysplastic syndrome9.9

Graphical network of the top 20 diseases related to Granulomatous Dermatitis:



Diseases related to granulomatous dermatitis

Symptoms for Granulomatous Dermatitis

About this section

Drugs & Therapeutics for Granulomatous Dermatitis

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Granulomatous Dermatitis

Genetic Tests for Granulomatous Dermatitis

About this section

Anatomical Context for Granulomatous Dermatitis

About this section

MalaCards organs/tissues related to Granulomatous Dermatitis:

33
Neutrophil, Lung, Skin, Bone, Brain, Prostate, Breast

Animal Models for Granulomatous Dermatitis or affiliated genes

About this section

MGI Mouse Phenotypes related to Granulomatous Dermatitis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053798.7ACE, FOXC1, TNF, TNFRSF1B
2MP:00053708.7ACE, FOXC1, TNF, TNFRSF1B
3MP:00053818.2FOXC1, NOD2, TNF, TNFRSF1B
4MP:00053907.9FOXC1, NOD2, TNF, TNFRSF1B
5MP:00053767.7ACE, FOXC1, NOD2, TNF, TNFRSF1B
6MP:00053787.5ACE, FOXC1, NOD2, TNF, TNFRSF1B

Publications for Granulomatous Dermatitis

About this section

Articles related to Granulomatous Dermatitis:

(show top 50)    (show all 158)
idTitleAuthorsYear
1
The rope sign: a case of interstitial granulomatous dermatitis with arthritis. (26924028)
2016
2
Palisaded Neutrophilic Granulomatous Dermatitis in a Child with Juvenile Idiopathic Arthritis on Etanercept. (26860064)
2016
3
Interstitial Granulomatous Dermatitis as the Initial Manifestation of Myeloma. (26039702)
2015
4
Granulomatous Dermatitis as a Cutaneous Manifestation of Hematologic Disorders: The First Case Associated With Polycythemia Vera and a New Case Associated With Myelodysplasia. (26703820)
2015
5
Chronic Interstitial Granulomatous Dermatitis in Coccidioidomycosis. (26574343)
2015
6
Interstitial granulomatous dermatitis: rare cutaneous manifestation of rheumatoid arthritis. (26131871)
2015
7
Interstitial Granulomatous Dermatitis Associated with Myelodysplastic Syndrome - Complete Clearance Under Therapy with 5-azacytidine. (24573709)
2014
8
Ustekinumab therapy for severe interstitial granulomatous dermatitis with arthritis. (23677104)
2013
9
Palisaded neutrophilic and granulomatous dermatitis in association with subcutaneous nodular and systemic sarcoidosis. (24476612)
2013
10
Perforating granulomatous dermatitis reaction to exogenous tattoo pigment: a case report and review of the literature. (21986232)
2013
11
Generalized Granulomatous Dermatitis Accompanied by Myelodysplastic Syndrome. (23817627)
2013
12
A palpable erythematous cord over the trunk in a patient with systemic lupus erythematosus. Interstitial granulomatous dermatitis (IGD). (23677093)
2013
13
Combination therapy with intralesional triamcinolone and oral dapsone for management of palisaded neutrophilic and granulomatous dermatitis. (23473287)
2013
14
Interstitial granulomatous dermatitis and arthritis revealing oesophageal carcinoma. (23777491)
2013
15
A cutaneous interstitial granulomatous dermatitis-like eruption arising in myelodysplasia with leukemic progression. (23221468)
2013
16
Interstitial granulomatous dermatitis with arthritis presenting with the rope sign. (23531209)
2013
17
Palisaded neutrophilic and granulomatous dermatitis in an adolescent girl with perinuclear antineutrophil cytoplasmic antibody-positive pauci-immune glomerulonephritis and arthritis. (22980283)
2012
18
Interstitial granulomatous dermatitis: a distinct entity with characteristic histological and clinical pattern. (22059717)
2012
19
Interstitial granulomatous dermatitis? An unusual presentation in the mucosa and periungual skin. (21352283)
2011
20
Interstitial granulomatous dermatitis in a patient with lupus erythematosus. (21986235)
2011
21
Isolated unilateral palisaded neutrophilic and granulomatous dermatitis. (21860170)
2011
22
Palisaded neutrophilic and granulomatous dermatitis in association with sarcoidosis. (20528967)
2011
23
Interstitial granulomatous dermatitis: another clinical variant. (22087092)
2011
24
Palisaded neutrophilic and granulomatous dermatitis: a presenting sign of sarcoidosis? (21839329)
2011
25
Interstitial granulomatous dermatitis in rheumatoid arthritis responsive to etanercept. (19802716)
2010
26
Necrotizing palisaded granulomatous dermatitis as a manifestation of familial hemophagocytic lymphohistiocytosis. (19903216)
2010
27
Interstitial granulomatous dermatitis in a patient with rheumatoid arthritis on etanercept. (19271571)
2009
28
Interstitial granulomatous dermatitis in a child with chronic uveitis. (18489032)
2008
29
Interstitial granulomatous dermatitis in a patient with rheumatoid arthritis on etanercept. (18491481)
2008
30
Early lesion of palisaded neutrophilic granulomatous dermatitis in ulcerative colitis. (17483043)
2007
31
Interstitial granulomatous dermatitis associated with autoimmune hepatitis. (17447986)
2007
32
Infliximab therapy for interstitial granulomatous dermatitis. (17243965)
2007
33
Perforating neutrophilic and granulomatous dermatitis of the newborn--a clue to immunodeficiency. (17542866)
2007
34
Lichenoid and granulomatous dermatitis associated with atypical mycobacterium infections. (16872476)
2006
35
Interstitial granulomatous dermatitis associated with the use of tumor necrosis factor alpha inhibitors. (16490847)
2006
36
Palisaded neutrophilic granulomatous dermatitis presenting as an unusual skin manifestation in a patient with BehAset's disease. (16195168)
2005
37
Palisaded neutrophilic and granulomatous dermatitis: an unusual cutaneous manifestation of immune-mediated disorders. (15609265)
2004
38
Interstitial granulomatous dermatitis with plaques and arthritis. (14579165)
2003
39
Interstitial granulomatous dermatitis with histiocytic pseudorosettes: a new histopathologic pattern in cutaneous borreliosis. Detection of Borrelia burgdorferi DNA sequences by a highly sensitive PCR-ELISA. (12637917)
2003
40
Interstitial granulomatous dermatitis with plaques and arthritis. (12804998)
2003
41
Photo quiz. Palisaded neutrophilic and granulomatous dermatitis with underlying Wegener's granulomatosis. (12184668)
2002
42
Interstitial granulomatous dermatitis with plaques. (12063487)
2002
43
Lichenoid and granulomatous dermatitis. (10692062)
2000
44
The histopathologic spectrum of palisaded neutrophilic and granulomatous dermatitis in patients with collagen vascular disease. (7944509)
1994
45
Granulomatous dermatitis and Zyderm. (8016250)
1994
46
Granulomatous dermatitis to iron oxide after permanent pigmentation of the eyebrows. (8454784)
1993
47
Granulomatous dermatitis in peach-faced lovebirds. (3426471)
1987
48
Recurrent granulomatous dermatitis with eosinophilia. Wells' syndrome. (6724778)
1984
49
Periocular dermatitis: a micropapular sarcoid-like granulomatous dermatitis in a woman. (7250477)
1981
50
Wells' syndrome. Recurrent granulomatous dermatitis with eosinophilia. (443839)
1979

Variations for Granulomatous Dermatitis

About this section

Expression for genes affiliated with Granulomatous Dermatitis

About this section
Search GEO for disease gene expression data for Granulomatous Dermatitis.

Pathways for genes affiliated with Granulomatous Dermatitis

About this section

GO Terms for genes affiliated with Granulomatous Dermatitis

About this section

Biological processes related to Granulomatous Dermatitis according to GeneCards Suite gene sharing:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1blood vessel remodelingGO:00019749.9ACE, FOXC1
2apoptotic signaling pathwayGO:00971909.8TNF, TNFRSF1B
3intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.7TNF, TNFRSF1B
4extrinsic apoptotic signaling pathwayGO:00971919.6TNF, TNFRSF1B
5activation of MAPK activityGO:00001879.5NOD2, TNF
6regulation of cell proliferationGO:00421279.4TNF, TNFRSF1B
7defense responseGO:00069529.3NOD2, TNF
8positive regulation of NF-kappaB transcription factor activityGO:00510929.2NOD2, TNF
9defense response to bacteriumGO:00427429.1NOD2, TNF
10positive regulation of transcription from RNA polymerase II promoterGO:00459448.2FOXC1, NOD2, TNF

Sources for Granulomatous Dermatitis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet