MCID: GRN003
MIFTS: 31

Granulomatous Dermatitis malady

Category: Skin diseases

Aliases & Classifications for Granulomatous Dermatitis

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Aliases & Descriptions for Granulomatous Dermatitis:

Name: Granulomatous Dermatitis 11 13 67

Classifications:



External Ids:

Disease Ontology11 DOID:4397
NCIt44 C3505

Summaries for Granulomatous Dermatitis

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MalaCards based summary: Granulomatous Dermatitis is related to burns and granuloma annulare. An important gene associated with Granulomatous Dermatitis is NOD2 (Nucleotide Binding Oligomerization Domain Containing 2), and among its related pathways are Canonical NF-kappaB pathway and TNF signaling pathway. Affiliated tissues include neutrophil, skin and b cells, and related mouse phenotypes are digestive/alimentary and skeleton.

Related Diseases for Granulomatous Dermatitis

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Diseases related to Granulomatous Dermatitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 118)
idRelated DiseaseScoreTop Affiliating Genes
1burns29.5ACE, TNF
2granuloma annulare29.1ACE, TNF
3interstitial granulomatous dermatitis with arthritis12.1
4dermatitis10.7
5arthritis10.3
6crohn's colitis10.3NOD2, TNF
7phlyctenulosis10.3NOD2, TNF
8oropharynx cancer10.3NOD2, TNF
9spondylohypoplasia, arthrogryposis and popliteal pterygium10.3NOD2, TNF
10capillary lymphangioma10.2NOD2, TNF
11female reproductive system disease10.2NOD2, TNF
12uterine corpus endometrial stromal sarcoma10.2NOD2, TNF
13meier-gorlin syndrome 310.2NOD2, TNF
14gastroduodenal crohn's disease10.2NOD2, TNF
15keratosis10.2NOD2, TNF
16isolated congenital breast hypoplasia/aplasia10.2FOXC1, TNF
17psoriasis susceptibility 110.2NOD2, TNF
18rectum leiomyosarcoma10.2NOD2, TNF
19benign renovascular hypertension10.2NOD2, TNF
20perianal skin paget's disease10.1NOD2, TNF
21uveoparotid fever10.1ACE, TNF
22post-infectious myocarditis10.1ACE, TNF
23islet cell tumor10.1ACE, TNF
24oesophagostomiasis10.1ACE, TNF
25isolated congenital auditory ossicle malformation10.1ACE, TNF
26sinusitis10.1ACE, TNF
27discitis10.1ACE, TNF
28alcohol abuse10.1ACE, TNF
29renal fibrosis10.1ACE, TNF
30diphtheria10.1ACE, TNF
31anaerobic pneumonia10.1ACE, TNF
32renal tubular acidosis10.1ACE, TNF
33spinal canal and spinal cord meningioma10.1ACE, TNF
34diabetic encephalopathy10.0ACE, TNF
35lung hilum cancer10.0ACE, TNF
36rheumatoid arthritis10.0
37lupus erythematosus10.0
38short bowel syndrome10.0ACE, TNF
39periampullary adenoma10.0ACE, TNF
40aspartylglucosaminuria10.0NOD2, TNF
41systemic lupus erythematosus10.0
42laryngeal tuberculosis10.0ACE, TNF
43exocrine pancreatic insufficiency10.0ACE, TNF
44sacral spinal canal and spinal cord meningioma10.0ACE, TNF
45frontal sinus cancer10.0ACE, TNF
46common wart10.0ACE, TNF
47femoral neuropathy10.0ACE, TNF
48adult respiratory distress syndrome10.0ACE, TNF
49survival motor neuron spinal muscular atrophy9.9ACE, TNF
50craniosynostosis9.9ACE, TNF

Graphical network of the top 20 diseases related to Granulomatous Dermatitis:



Diseases related to granulomatous dermatitis

Symptoms for Granulomatous Dermatitis

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Drugs & Therapeutics for Granulomatous Dermatitis

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Granulomatous Dermatitis

Genetic Tests for Granulomatous Dermatitis

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Anatomical Context for Granulomatous Dermatitis

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MalaCards organs/tissues related to Granulomatous Dermatitis:

35
Neutrophil, Skin, B cells, T cells, Thyroid

Animal Models for Granulomatous Dermatitis or affiliated genes

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MGI Mouse Phenotypes related to Granulomatous Dermatitis:

40
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00053819.0BRAF, FOXC1, NOD2, TNF
2MP:00053908.9BRAF, FOXC1, NOD2, TNF
3MP:00053798.8ACE, BRAF, FOXC1, TNF
4MP:00053708.8ACE, BRAF, FOXC1, TNF
5MP:00053898.8ACE, BRAF, FOXC1, TNF
6MP:00053788.4ACE, BRAF, FOXC1, NOD2, TNF
7MP:00053768.3ACE, BRAF, FOXC1, NOD2, TNF

Publications for Granulomatous Dermatitis

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Articles related to Granulomatous Dermatitis:

(show top 50)    (show all 166)
idTitleAuthorsYear
1
Interstitial Granulomatous Dermatitis Associated with Rheumatoid Arthritis. (27274645)
2016
2
The rope sign: a case of interstitial granulomatous dermatitis with arthritis. (26924028)
2016
3
Interstitial granulomatous dermatitis occurring in a patient with SAPHO syndrome one month after starting leflunomide, and subsequently disappearing with ustekinumab. (27456988)
2016
4
Palisaded Neutrophilic Granulomatous Dermatitis in a Child with Juvenile Idiopathic Arthritis on Etanercept. (26860064)
2016
5
Interstitial Granulomatous Dermatitis as the Initial Manifestation of Myeloma. (26039702)
2015
6
Chronic Interstitial Granulomatous Dermatitis in Coccidioidomycosis. (26574343)
2015
7
Interstitial granulomatous dermatitis: rare cutaneous manifestation of rheumatoid arthritis. (26131871)
2015
8
Interstitial granulomatous dermatitis: a characteristic histological pattern with variable clinical manifestations. (26755914)
2015
9
Interstitial Granulomatous Dermatitis Associated with Myelodysplastic Syndrome - Complete Clearance Under Therapy with 5-azacytidine. (24573709)
2014
10
Post-varicella-zoster virus granulomatous dermatitis: a report of 2 cases. (24505586)
2014
11
Palisaded neutrophilic and granulomatous dermatitis in association with subcutaneous nodular and systemic sarcoidosis. (24476612)
2013
12
A palpable erythematous cord over the trunk in a patient with systemic lupus erythematosus. Interstitial granulomatous dermatitis (IGD). (23677093)
2013
13
Interstitial granulomatous dermatitis and arthritis revealing oesophageal carcinoma. (23777491)
2013
14
Palisaded neutrophilic and granulomatous dermatitis in a rheumatoid arthritis patient after treatment with adalimumab. (24201093)
2013
15
Interstitial granulomatous dermatitis: a distinct entity with characteristic histological and clinical pattern. (22059717)
2012
16
Lupus attributable to anti-TNF therapy and revealed by interstitial granulomatous dermatitis. (21800115)
2012
17
Intravenous immunoglobulins as a treatment of interstitial granulomatous dermatitis with arthritis. (22283232)
2012
18
Deep granulomatous dermatitis of the fin caused by Fusarium solani in a false killer whale (Pseudorca crassidens). (22214860)
2012
19
Interstitial granulomatous dermatitis? An unusual presentation in the mucosa and periungual skin. (21352283)
2011
20
Interstitial granulomatous dermatitis in a patient with lupus erythematosus. (21986235)
2011
21
Palisaded neutrophilic and granulomatous dermatitis in association with sarcoidosis. (20528967)
2011
22
Palisaded neutrophilic and granulomatous dermatitis: a presenting sign of sarcoidosis? (21839329)
2011
23
Palisaded neutrophilic granulomatous dermatitis without a definable underlying disorder treated with dapsone. (21839310)
2011
24
Palisaded neutrophilic granulomatous dermatitis caused by cellulitis in a patient with systemic lupus erythematosus. (22098012)
2011
25
Infectious granulomatous dermatitis associated with Rothia mucilaginosa bacteremia: A case report. (19940746)
2010
26
Interstitial granulomatous dermatitis with arthritis. (19891930)
2009
27
Drug-induced hypersensitivity syndrome with superficial granulomatous dermatitis--a novel finding. (19590408)
2009
28
Palisaded neutrophilic and granulomatous dermatitis in a child with type I diabetes mellitus and coeliac disease. (18503597)
2008
29
Early lesion of palisaded neutrophilic granulomatous dermatitis in ulcerative colitis. (17483043)
2007
30
Interstitial granulomatous dermatitis associated with autoimmune hepatitis. (17447986)
2007
31
Lichenoid and granulomatous dermatitis associated with atypical mycobacterium infections. (16872476)
2006
32
Granulomatous dermatitis with enlarged histiocytes: a characteristic pattern of granulocyte colony-stimulating factor. Report of two cases and review of the literature. (16484826)
2006
33
Interstitial granulomatous dermatitis with arthritis (Ackerman syndrome). (16755676)
2006
34
Mycobacterium intermedium granulomatous dermatitis from hot tub exposure. (16704844)
2006
35
Palisaded neutrophilic granulomatous dermatitis presenting as an unusual skin manifestation in a patient with BehAset's disease. (16195168)
2005
36
Palisaded neutrophilic and granulomatous dermatitis: an unusual cutaneous manifestation of immune-mediated disorders. (15609265)
2004
37
Interstitial granulomatous dermatitis with plaques and arthritis. (14579165)
2003
38
Interstitial granulomatous dermatitis with histiocytic pseudorosettes: a new histopathologic pattern in cutaneous borreliosis. Detection of Borrelia burgdorferi DNA sequences by a highly sensitive PCR-ELISA. (12637917)
2003
39
Interstitial granulomatous dermatitis with plaques and arthritis. (12804998)
2003
40
Photo quiz. Palisaded neutrophilic and granulomatous dermatitis with underlying Wegener's granulomatosis. (12184668)
2002
41
Interstitial granulomatous dermatitis with plaques. (12063487)
2002
42
Interstitial granulomatous dermatitis with cutaneous cords and arthritis: a disorder associated with autoantibodies. (11464193)
2001
43
A granulomatous dermatitis associated with idiopathic ulcerative colitis. (10759966)
2000
44
Sarcoidal foreign-body granulomatous dermatitis associated with ophthalmic drops. (9557788)
1998
45
A case of granulomatous dermatitis: cutaneous leishmaniasis. (9423232)
1997
46
Interstitial granulomatous dermatitis with arthritis. (8647988)
1996
47
Granulomatous dermatitis and Zyderm. (8016250)
1994
48
Granulomatous dermatitis to iron oxide after permanent pigmentation of the eyebrows. (8454784)
1993
49
Granulomatous dermatitis in peach-faced lovebirds. (3426471)
1987
50
Primary granulomatous dermatitis caused by Rhodochrous. Evidence for a pathogenic role in humans. (6651316)
1983

Variations for Granulomatous Dermatitis

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Expression for genes affiliated with Granulomatous Dermatitis

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Search GEO for disease gene expression data for Granulomatous Dermatitis.

Pathways for genes affiliated with Granulomatous Dermatitis

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Pathways related to Granulomatous Dermatitis according to GeneCards Suite gene sharing:

idSuper pathwaysScoreTop Affiliating Genes
19.5NOD2, TNF
29.5NOD2, TNF
3
Show member pathways
9.1BRAF, TNF

GO Terms for genes affiliated with Granulomatous Dermatitis

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Biological processes related to Granulomatous Dermatitis according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of NIK/NF-kappaB signalingGO:190122410.1NOD2, TNF
2JNK cascadeGO:000725410.0NOD2, TNF
3positive regulation of JNK cascadeGO:004633010.0NOD2, TNF
4positive regulation of interleukin-6 productionGO:00327559.8NOD2, TNF
5defense responseGO:00069529.8NOD2, TNF
6kidney developmentGO:00018229.8ACE, FOXC1
7cellular response to organic cyclic compoundGO:00714079.8NOD2, TNF
8positive regulation of interleukin-8 productionGO:00327579.7NOD2, TNF
9activation of MAPK activityGO:00001879.6NOD2, TNF
10blood vessel remodelingGO:00019749.5ACE, FOXC1
11positive regulation of peptidyl-serine phosphorylationGO:00331389.2BRAF, TNF
12positive regulation of ERK1 and ERK2 cascadeGO:00703748.7BRAF, NOD2, TNF
13positive regulation of gene expressionGO:00106288.3BRAF, FOXC1, TNF

Molecular functions related to Granulomatous Dermatitis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1mitogen-activated protein kinase kinase bindingGO:00314349.0ACE, BRAF

Sources for Granulomatous Dermatitis

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
26GTR
27HGMD
28HMDB
29ICD10
30ICD10 via Orphanet
31ICD9CM
32IUPHAR
33KEGG
36MedGen
38MeSH
39MESH via Orphanet
40MGI
43NCI
44NCIt
45NDF-RT
48NINDS
49Novoseek
51OMIM
52OMIM via Orphanet
56PubMed
57QIAGEN
62SNOMED-CT via Orphanet
66Tumor Gene Family of Databases
67UMLS
68UMLS via Orphanet