MCID: GRN003
MIFTS: 32

Granulomatous Dermatitis malady

Summaries for Granulomatous Dermatitis

About this section
Sources:
32MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
MalaCards: Granulomatous Dermatitis is related to dermatitis and rheumatoid arthritis. An important gene associated with Granulomatous Dermatitis is NOD2 (nucleotide-binding oligomerization domain containing 2), and among its related pathways are Toll-Like receptor Signaling Pathways and Leishmaniasis. The compounds prednisolone and il 10 have been mentioned in the context of this disorder. Affiliated tissues include skin, thyroid and t cells.

Aliases & Classifications for Granulomatous Dermatitis

About this section
Sources:
8Disease Ontology, 60UMLS, 39NCIt
See all sources

Aliases & Descriptions:

granulomatous dermatitis 8 60


External Ids:

Disease Ontology8 DOID:4397
NCIt39 C3505

Related Diseases for Granulomatous Dermatitis

About this section
Sources:
17GeneCards, 18GeneDecks
See all sources

Graphical network of the top 20 diseases related to Granulomatous Dermatitis:



Diseases related to granulomatous dermatitis

Clinical Features for Granulomatous Dermatitis

About this section

Drugs & Therapeutics for Granulomatous Dermatitis

About this section
Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Granulomatous Dermatitis

Drug clinical trials:

Search ClinicalTrials for Granulomatous Dermatitis

Search NIH Clinical Center for Granulomatous Dermatitis

Search CenterWatch for Granulomatous Dermatitis

Genetic Tests for Granulomatous Dermatitis

About this section

Anatomical Context for Granulomatous Dermatitis

About this section
Sources:
32MalaCards
See all sources

MalaCards organs/tissues related to Granulomatous Dermatitis:

32
Skin, Thyroid, T cells

Animal Models for Granulomatous Dermatitis or affiliated genes

About this section

Publications for Granulomatous Dermatitis

About this section
Sources:
50PubMed
See all sources

Articles related to Granulomatous Dermatitis:

(show top 50)    (show all 136)
idTitleAuthorsYear
1
Crystal deodorant-induced axillary granulomatous dermatitis. (23621443)
2014
2
Generalized Granulomatous Dermatitis Accompanied by Myelodysplastic Syndrome. (23817627)
2013
3
A child with interstitial granulomatous dermatitis and juvenile idiopathic arthritis. (23735003)
2013
4
Interstitial granulomatous dermatitis: a distinct entity with characteristic histological and clinical pattern. (22059717)
2012
5
Granuloma annulare associated with cutaneous marginal zone lymphoma: a case linking a hematologic malignancy with granulomatous dermatitis. (22935889)
2012
6
Acute New World cutaneous leishmaniasis presenting as tuberculoid granulomatous dermatitis. (22236114)
2012
7
Expression of CD163 in granulomatous dermatitis is not the tool that makes the difference. (21651621)
2012
8
Isolated unilateral palisaded neutrophilic and granulomatous dermatitis. (21860170)
2011
9
Palisaded neutrophilic and granulomatous dermatitis: a presenting sign of sarcoidosis? (21839329)
2011
10
Churg-Strauss syndrome with coexistence of eosinophilic vasculitis, granulomatous phlebitis and granulomatous dermatitis in bullous pemphigoid-like blisters. (20132420)
2011
11
Myelodysplastic syndrome presenting as generalized granulomatous dermatitis. (21422341)
2011
12
Necrotizing palisaded granulomatous dermatitis as a manifestation of familial hemophagocytic lymphohistiocytosis. (19903216)
2010
13
Infectious granulomatous dermatitis associated with Rothia mucilaginosa bacteremia: A case report. (19940746)
2010
14
Interstitial granulomatous dermatitis (Ackerman's Syndrome). (20627851)
2010
15
Localized acquired cutis laxa secondary to interstitial granulomatous dermatitis. (19438565)
2009
16
Birefringent particles in granulomatous dermatitis, sarcoidal-type, as well as in other non-granulomatous skin disorders in patients without sarcoidosis. (19634571)
2009
17
Interstitial granulomatous dermatitis in a child with chronic uveitis. (18489032)
2008
18
Interstitial granulomatous dermatitis in a patient with rheumatoid arthritis on etanercept. (18491481)
2008
19
Palisaded neutrophilic and granulomatous dermatitis associated with limited systemic sclerosis. (17945384)
2008
20
Delayed reaction after an octopus bite showing a giant cell-rich granulomatous dermatitis/panniculitis. (18544063)
2008
21
Interstitial granulomatous dermatitis associated with autoimmune hepatitis. (17447986)
2007
22
Clinical vignette. Interstitial granulomatous dermatitis (Ackerman's syndrome) in SLE presenting with the 'rope sign'. (16935918)
2007
23
Granulomatous dermatitis with enlarged histiocytes: a characteristic pattern of granulocyte colony-stimulating factor. Report of two cases and review of the literature. (16484826)
2006
24
Palisaded neutrophilic granulomatous dermatitis in a 12-year-old girl with systemic lupus erythematosus. (16843132)
2006
25
Mycobacterium intermedium granulomatous dermatitis from hot tub exposure. (16704844)
2006
26
A novel case of polyfibromatosis and interstitial granulomatous dermatitis with arthritis. (16843121)
2006
27
Adverse effects of cosmetic tattooing: an illustrative case of granulomatous dermatitis following the application of permanent makeup. (17043202)
2006
28
Palisaded neutrophilic granulomatous dermatitis presenting as an unusual skin manifestation in a patient with BehAset's disease. (16195168)
2005
29
Granulomatous rosacea mimicking eyelid dermatitis. (16394471)
2005
30
Adverse effects of cosmetic tattooing: an illustrative case of granulomatous dermatitis following the application of permanent makeup. (16027323)
2005
31
Interstitial granulomatous dermatitis with plaques associated with antiphospholipid syndrome. (15840129)
2005
32
Palisaded neutrophilic and granulomatous dermatitis. (16045697)
2005
33
Interstitial granulomatous dermatitis with arthritis. (15257555)
2004
34
Interstitial granulomatous dermatitis secondary to soy. (15280826)
2004
35
Interstitial granulomatous dermatitis with histiocytic pseudorosettes: a new histopathologic pattern in cutaneous borreliosis. Detection of Borrelia burgdorferi DNA sequences by a highly sensitive PCR-ELISA. (12637917)
2003
36
Interstitial granulomatous dermatitis with plaques and arthritis. (12804998)
2003
37
Arthritis and interstitial granulomatous dermatitis (Ackerman syndrome) with pulmonary silicosis. (12701044)
2003
38
Palisaded neutrophilic and granulomatous dermatitis. (14594574)
2003
39
Photo quiz. Palisaded neutrophilic and granulomatous dermatitis with underlying Wegener's granulomatosis. (12184668)
2002
40
Interstitial granulomatous dermatitis with plaques. (12063487)
2002
41
Interstitial granulomatous dermatitis associated with pulmonary coccidioidomycosis. (11712027)
2001
42
Interstitial granulomatous drug reaction with a histological pattern of interstitial granulomatous dermatitis. (11481519)
2001
43
Lichenoid and granulomatous dermatitis. (10692062)
2000
44
A granulomatous dermatitis associated with idiopathic ulcerative colitis. (10759966)
2000
45
Granulomatous dermatitis with focal sarcoidal features associated with recombinant interferon beta-1b injections. (9843024)
1998
46
Granulomatous dermatitis to iron oxide after permanent pigmentation of the eyebrows. (8454784)
1993
47
Granulomatous dermatitis in peach-faced lovebirds. (3426471)
1987
48
Periocular dermatitis: a micropapular sarcoid-like granulomatous dermatitis in a woman. (7250477)
1981
49
Wells' syndrome: recurrent granulomatous dermatitis with eosinophilia. (7316547)
1981
50
Recurrent granulomatous dermatitis with eosinophilia. (5570262)
1971

Genetic Variations for Granulomatous Dermatitis

About this section

Expression for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Granulomatous Dermatitis

Search GEO for disease gene expression data for Granulomatous Dermatitis.

Pathways for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
52R&D Systems, 29KEGG, 37NCBI BioSystems Database, 53Reactome
See all sources

Compounds for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
44Novoseek, 28IUPHAR, 11DrugBank, 49PharmGKB, 24HMDB
See all sources

Compounds related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1prednisolone44 28 1111.6NOD2
2il 10449.4NOD2, TNF
3infliximab44 49 1111.4NOD2, TNF
4peptidoglycan44 2810.3NOD2, TNF
5prostacyclin449.1ACE, TNF
6nitric oxide44 11 2410.4TNF, NOD2, ACE

GO Terms for genes affiliated with Granulomatous Dermatitis

About this section
Sources:
16Gene Ontology
See all sources

Cellular components related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1external side of plasma membraneGO:0098979.1ACE, TNF

Biological processes related to Granulomatous Dermatitis according to GeneCards/GeneDecks:

(show all 10)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of humoral immune response mediated by circulating immunoglobulinGO:0029259.6NOD2, TNF
2negative regulation of growth of symbiont in hostGO:0441309.5NOD2, TNF
3defense response to Gram-positive bacteriumGO:0508309.5TNF, NOD2
4positive regulation of interleukin-6 productionGO:0327559.5NOD2, TNF
5positive regulation of JNK cascadeGO:0463309.4NOD2, TNF
6JNK cascadeGO:0072549.4TNF, NOD2
7activation of MAPK activityGO:0001879.3NOD2, TNF
8positive regulation of I-kappaB kinase/NF-kappaB cascadeGO:0431239.3NOD2, TNF
9positive regulation of ERK1 and ERK2 cascadeGO:0703749.2NOD2, TNF
10positive regulation of NF-kappaB transcription factor activityGO:0510929.0NOD2, TNF

Products for genes affiliated with Granulomatous Dermatitis

About this section
  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Granulomatous Dermatitis

About this section
3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet