MCID: GRN036
MIFTS: 25

Granulomatous Myositis

Categories: Muscle diseases

Aliases & Classifications for Granulomatous Myositis

MalaCards integrated aliases for Granulomatous Myositis:

Name: Granulomatous Myositis 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:3428
NCIt 46 C27575
UMLS 69 C1334150

Summaries for Granulomatous Myositis

MalaCards based summary : Granulomatous Myositis is related to myositis and asphyxia neonatorum. An important gene associated with Granulomatous Myositis is NAIP (NLR Family Apoptosis Inhibitory Protein). Affiliated tissues include tongue and t cells, and related phenotypes are cellular and hematopoietic system

Related Diseases for Granulomatous Myositis

Diseases related to Granulomatous Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 91)
# Related Disease Score Top Affiliating Genes
1 myositis 30.8 NCAM1 PIK3C2A TTN
2 asphyxia neonatorum 10.4 PIK3C2A TTN
3 spinal muscular atrophy, type ii 10.4 NAIP NCAM1
4 erysipelas 10.3 LYZ PIK3C2A
5 pleomorphic adenoma carcinoma 10.3 LYZ PTHLH
6 angiomyoma 10.3 NCAM1 PTHLH
7 virus associated hemophagocytic syndrome 10.3 CD68 PIK3C2A
8 fiedler's myocarditis 10.3 CD68 PIK3C2A
9 central nervous system sarcoma 10.3 CD68 LYZ
10 malignant giant cell tumor of soft parts 10.3 CD68 LYZ
11 melanotic neurilemmoma 10.2 CD68 LYZ
12 adult xanthogranuloma 10.2 CD68 LYZ
13 gallbladder small cell carcinoma 10.2 NCAM1 SMUG1
14 periodic fever, familial, autosomal dominant 10.2 LYZ TNFRSF1B
15 acute salpingitis 10.2 LYZ TNFRSF1B
16 laryngeal tuberculosis 10.2 LYZ SMUG1
17 parasitic ichthyosporea infectious disease 10.2 CD68 NCAM1
18 rectum squamous cell carcinoma 10.2 SMUG1 TNFRSF1B
19 rhinosporidiosis 10.2 CD68 NCAM1
20 plexopathy 10.2 PIK3C2A SMUG1
21 endometrial small cell carcinoma 10.2 NCAM1 SMUG1
22 pancoast tumor 10.2 SMUG1 TNFRSF1B
23 mediastinal cancer 10.2 NCAM1 SMUG1
24 hemangioma of intra-abdominal structure 10.2 CD68 PTHLH
25 lymphangiosarcoma 10.2 LYZ SMUG1
26 chondromalacia 10.2 SMUG1 TNFRSF1B
27 pulmonary artery leiomyosarcoma 10.1 CD68 SMUG1
28 legionellosis 10.1 NAIP PIK3C2A
29 congenital epulis 10.1 CD68 LYZ
30 brain sarcoma 10.1 CD68 SMUG1
31 ulcerative stomatitis 10.1 CD68 LYZ
32 scrotal carcinoma 10.1 CD68 SMUG1
33 malignant skin fibrous histiocytoma 10.1 NCAM1 SMUG1
34 tolosa-hunt syndrome 10.1 PRTN3 SMUG1
35 orbital plasma cell granuloma 10.1 NCAM1 PIK3C2A TNFRSF1B
36 granulomatous gastritis 10.1 CD68 PRTN3
37 in situ pulmonary adenocarcinoma 10.1 LYZ SMUG1
38 malignant dermis tumor 10.0 NCAM1 SMUG1
39 pulmonary hemosiderosis 10.0 LYZ PRTN3
40 liver sarcoma 10.0 CD68 LYZ PTHLH
41 eumycotic mycetoma 10.0 CD68 SMUG1
42 pericardial tuberculosis 10.0 PRTN3 SMUG1
43 aleukemic leukemia cutis 10.0 CD68 LYZ NCAM1
44 multiple cranial nerve palsy 9.9 NCAM1 PRTN3
45 lymphatic system cancer 9.9 LYZ TNFRSF8
46 hypersensitivity reaction type iv disease 9.9 LYZ SMUG1 TNFRSF1B
47 pericoronitis 9.9 CD68 NCAM1 TNFRSF1B
48 cogan syndrome 9.9 SMUG1 TNFRSF1B
49 rhinoscleroma 9.9 CD68 NCAM1 TNFRSF1B
50 hodgkin's lymphoma, lymphocytic depletion 9.9 CD68 TNFRSF8

Graphical network of the top 20 diseases related to Granulomatous Myositis:



Diseases related to Granulomatous Myositis

Symptoms & Phenotypes for Granulomatous Myositis

MGI Mouse Phenotypes related to Granulomatous Myositis:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.76 PRTN3 PTHLH SMUG1 TNFRSF1B TTN LYZ
2 hematopoietic system MP:0005397 9.5 CD68 LYZ PIK3C2A PRTN3 PTHLH TNFRSF1B
3 immune system MP:0005387 9.23 CD68 LYZ PIK3C2A PRTN3 PTHLH TNFRSF1B

Drugs & Therapeutics for Granulomatous Myositis

Search Clinical Trials , NIH Clinical Center for Granulomatous Myositis

Genetic Tests for Granulomatous Myositis

Anatomical Context for Granulomatous Myositis

MalaCards organs/tissues related to Granulomatous Myositis:

38
Tongue, T Cells

Publications for Granulomatous Myositis

Articles related to Granulomatous Myositis:

(show all 26)
# Title Authors Year
1
Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome. ( 28132973 )
2017
2
Hypercalcemia revealing diffuse granulomatous myositis. ( 28396910 )
2017
3
A case of late-onset, thymoma-associated myasthenia gravis with ryanodine receptor and titin antibodies and concomitant granulomatous myositis. ( 27623618 )
2016
4
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent. ( 27832822 )
2016
5
Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. ( 27692540 )
2016
6
LETTER TO THE EDITOR Atypical Granulomatous Myositis and Pulmonary Sarcoidosis. ( 26312107 )
2015
7
Diagnosis and classification of granulomatous myositis. ( 24424169 )
2014
8
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis. ( 22519739 )
2012
9
Granulomatous myositis associated with brucellosis: a case report and literature review. ( 22246889 )
2012
10
Granulomatous myositis associated with a novel alveolate pathogen in an adult southern leopard frog (Lithobates sphenocephalus). ( 23269391 )
2012
11
Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis. ( 20562458 )
2011
12
Granulomatous myositis mimicking slowly progressive lower motor neuron disease. ( 18700190 )
2008
13
Paediatric contracturing granulomatous myositis. ( 18821276 )
2008
14
Granulomatous myositis in association with chronic graft vs. host disease. ( 17970330 )
2007
15
Granulomatous myositis: a clinical study of thirteen cases. ( 17068767 )
2007
16
An autopsy case of aggressive CD30+ extra-nodal NK/T-cell lymphoma initially manifested with granulomatous myositis. ( 16321870 )
2006
17
Suppurative granulomatous myositis of an extra-ocular muscle in Crohn's disease. ( 16128967 )
2005
18
Granulomatous myositis associated with antithyroglobulin and antithyroid peroxidase antibodies: an analogy to Hashimoto's encephalitis? ( 12532931 )
2002
19
Granulomatous myositis: a manifestation of chronic graft-versus-host disease. ( 11904691 )
2002
20
Uptake of Ga-67 in granulomatous myositis with magnetic resonance imaging correlation. ( 11564935 )
2001
21
Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma. ( 10883012 )
2000
22
Idiopathic granulomatous myositis: does the clinical spectrum include polymyalgia rheumatica? ( 18639165 )
1999
23
Granulomatous myositis. Clinicopathologic study of 12 cases. ( 10396287 )
1999
24
Case report: MR features of granulomatous myositis. ( 9366543 )
1997
25
Tongue involvement in a patient with granulomatous myositis. ( 9305307 )
1997
26
Granulomatous myositis: pathologic re-evaluation by immunohistochemical analysis of infiltrating mononuclear cells. ( 9073027 )
1997

Variations for Granulomatous Myositis

Expression for Granulomatous Myositis

Search GEO for disease gene expression data for Granulomatous Myositis.

Pathways for Granulomatous Myositis

GO Terms for Granulomatous Myositis

Cellular components related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.17 LYZ NAIP NCAM1 PIK3C2A PRTN3 TNFRSF8

Biological processes related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.26 CD68 LYZ PRTN3 TNFRSF1B
2 inflammatory response GO:0006954 8.92 LYZ NAIP TNFRSF1B TNFRSF8

Molecular functions related to Granulomatous Myositis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 8.62 TNFRSF1B TNFRSF8

Sources for Granulomatous Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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