MCID: GRN036
MIFTS: 23

Granulomatous Myositis

Categories: Muscle diseases

Aliases & Classifications for Granulomatous Myositis

MalaCards integrated aliases for Granulomatous Myositis:

Name: Granulomatous Myositis 12 14

Classifications:



External Ids:

Disease Ontology 12 DOID:3428
NCIt 47 C27575
UMLS 69 C1334150

Summaries for Granulomatous Myositis

MalaCards based summary : Granulomatous Myositis is related to autistic disorder and spinal muscular atrophy-3. An important gene associated with Granulomatous Myositis is NAIP (NLR Family Apoptosis Inhibitory Protein). Affiliated tissues include tongue and t cells, and related phenotypes are cellular and hematopoietic system

Related Diseases for Granulomatous Myositis

Diseases related to Granulomatous Myositis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 86)
id Related Disease Score Top Affiliating Genes
1 autistic disorder 10.6 PIK3C2A TTN
2 spinal muscular atrophy-3 10.6 NAIP NCAM1
3 myelodysplastic myeloproliferative cancer 10.6 PIK3C2A TTN
4 tetanus 10.5 LYZ PIK3C2A
5 cystic kidney disease 10.5 LYZ PTHLH
6 visual snow syndrome 10.5 CD68 PIK3C2A
7 encephalitozoonosis 10.5 NCAM1 PTHLH
8 primary polycythemia 10.5 CD68 PIK3C2A
9 urethral urothelial papilloma 10.4 CD68 LYZ
10 localized pulmonary fibrosis 10.4 CD68 LYZ
11 tropical spastic paraparesis 10.4 CD68 LYZ
12 testicular spermatocytic seminoma 10.4 CD68 LYZ
13 cystitis cystica 10.4 NCAM1 SMUG1
14 thrombocytopenia due to platelet alloimmunization 10.4 LYZ SMUG1
15 multiple sclerosis 5 10.4 LYZ TNFRSF1B
16 aniseikonia 10.3 CD68 NCAM1
17 cutaneous ganglioneuroma 10.3 CD68 NCAM1
18 discitis 10.3 LYZ TNFRSF1B
19 ovarian squamous cell carcinoma 10.3 SMUG1 TNFRSF1B
20 thymus small cell carcinoma 10.3 NCAM1 SMUG1
21 brachial plexus neuropathy 10.3 PIK3C2A SMUG1
22 endodermal sinus tumor 10.3 CD68 LYZ
23 benign pericardial teratoma 10.3 SMUG1 TNFRSF1B
24 lyme disease 10.3 PIK3C2A TTN
25 myositis 10.3
26 morphine dependence 10.3 SMUG1 TNFRSF1B
27 malignant teratoma 10.3 NCAM1 SMUG1
28 adult intracranial malignant hemangiopericytoma 10.3 NCAM1 PIK3C2A TTN
29 tactile epilepsy 10.3 CD68 PTHLH
30 colonic l-cell glucagon-like peptide producing tumor 10.3 CD68 SMUG1
31 teeth hard tissue disease 10.3 CD68 SMUG1
32 plantar fasciitis 10.2 CD68 PIK3C2A
33 mucin-rich endometrial endometrioid adenocarcinoma 10.2 CD68 LYZ
34 toxic myocarditis 10.2 CD68 LYZ
35 penis paget's disease 10.2 CD68 SMUG1
36 postinflammatory pulmonary fibrosis 10.2 LYZ PRTN3
37 vaginal yolk sac tumor 10.2 NCAM1 SMUG1
38 primary lacrimal atrophy 10.2 PRTN3 TNFRSF1B
39 muscle cancer 10.1 CD68 PRTN3
40 ocular motility disease 10.1 PRTN3 SMUG1
41 periventricular leukomalacia 10.1 CD68 SMUG1
42 pigmented villonodular synovitis 10.1 CD68 LYZ PTHLH
43 large cell neuroendocrine carcinoma 10.1 LYZ SMUG1
44 hydrarthrosis 10.1 NCAM1 SMUG1
45 gerstmann syndrome 10.1 PRTN3 SMUG1
46 central nervous system mature teratoma 10.0 CD68 LYZ NCAM1
47 membranoproliferative glomerulonephritis 10.0 LYZ SMUG1 TNFRSF1B
48 pulmonary plasma cell granuloma 9.9 CD68 NCAM1 TNFRSF1B
49 pneumocystosis 9.9 CD68 NCAM1 TNFRSF1B
50 chronic intestinal vascular insufficiency 9.9 CD68 TNFRSF8

Graphical network of the top 20 diseases related to Granulomatous Myositis:



Diseases related to Granulomatous Myositis

Symptoms & Phenotypes for Granulomatous Myositis

MGI Mouse Phenotypes related to Granulomatous Myositis:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.76 LYZ NCAM1 PIK3C2A PRTN3 PTHLH SMUG1
2 hematopoietic system MP:0005397 9.5 PRTN3 PTHLH TNFRSF1B TNFRSF8 CD68 LYZ
3 immune system MP:0005387 9.23 CD68 LYZ PIK3C2A PRTN3 PTHLH TNFRSF1B

Drugs & Therapeutics for Granulomatous Myositis

Search Clinical Trials , NIH Clinical Center for Granulomatous Myositis

Genetic Tests for Granulomatous Myositis

Anatomical Context for Granulomatous Myositis

MalaCards organs/tissues related to Granulomatous Myositis:

39
Tongue, T Cells

Publications for Granulomatous Myositis

Articles related to Granulomatous Myositis:

(show all 26)
id Title Authors Year
1
Non-granulomatous myositis in a patient with ulcerative colitis who showed symptoms resembling gastrocnemius myalgia syndrome. ( 28132973 )
2017
2
Hypercalcemia revealing diffuse granulomatous myositis. ( 28396910 )
2017
3
A case of late-onset, thymoma-associated myasthenia gravis with ryanodine receptor and titin antibodies and concomitant granulomatous myositis. ( 27623618 )
2016
4
Sporadic inclusion body myositis misdiagnosed as idiopathic granulomatous myositis. ( 27692540 )
2016
5
Sarcoidosis presenting as granulomatous myositis in a 16-year-old adolescent. ( 27832822 )
2016
6
LETTER TO THE EDITOR Atypical Granulomatous Myositis and Pulmonary Sarcoidosis. ( 26312107 )
2015
7
Diagnosis and classification of granulomatous myositis. ( 24424169 )
2014
8
Granulomatous myositis associated with a novel alveolate pathogen in an adult southern leopard frog (Lithobates sphenocephalus). ( 23269391 )
2012
9
A case of systemic anaplastic lymphoma kinase-negative anaplastic large cell lymphoma associated with hypereosinophilia, granulomatous myositis and vasculitis. ( 22519739 )
2012
10
Granulomatous myositis associated with brucellosis: a case report and literature review. ( 22246889 )
2012
11
Distal muscle involvement in granulomatous myositis can mimic inclusion body myositis. ( 20562458 )
2011
12
Paediatric contracturing granulomatous myositis. ( 18821276 )
2008
13
Granulomatous myositis mimicking slowly progressive lower motor neuron disease. ( 18700190 )
2008
14
Granulomatous myositis in association with chronic graft vs. host disease. ( 17970330 )
2007
15
Granulomatous myositis: a clinical study of thirteen cases. ( 17068767 )
2007
16
An autopsy case of aggressive CD30+ extra-nodal NK/T-cell lymphoma initially manifested with granulomatous myositis. ( 16321870 )
2006
17
Suppurative granulomatous myositis of an extra-ocular muscle in Crohn's disease. ( 16128967 )
2005
18
Granulomatous myositis associated with antithyroglobulin and antithyroid peroxidase antibodies: an analogy to Hashimoto's encephalitis? ( 12532931 )
2002
19
Granulomatous myositis: a manifestation of chronic graft-versus-host disease. ( 11904691 )
2002
20
Uptake of Ga-67 in granulomatous myositis with magnetic resonance imaging correlation. ( 11564935 )
2001
21
Granulomatous myositis, primary biliary cirrhosis, pancytopenia, and thymoma. ( 10883012 )
2000
22
Idiopathic granulomatous myositis: does the clinical spectrum include polymyalgia rheumatica? ( 18639165 )
1999
23
Granulomatous myositis. Clinicopathologic study of 12 cases. ( 10396287 )
1999
24
Tongue involvement in a patient with granulomatous myositis. ( 9305307 )
1997
25
Case report: MR features of granulomatous myositis. ( 9366543 )
1997
26
Granulomatous myositis: pathologic re-evaluation by immunohistochemical analysis of infiltrating mononuclear cells. ( 9073027 )
1997

Variations for Granulomatous Myositis

Expression for Granulomatous Myositis

Search GEO for disease gene expression data for Granulomatous Myositis.

Pathways for Granulomatous Myositis

GO Terms for Granulomatous Myositis

Cellular components related to Granulomatous Myositis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.17 LYZ NAIP NCAM1 PIK3C2A PRTN3 TNFRSF8

Biological processes related to Granulomatous Myositis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 neutrophil degranulation GO:0043312 9.26 CD68 LYZ PRTN3 TNFRSF1B
2 inflammatory response GO:0006954 8.92 LYZ NAIP TNFRSF1B TNFRSF8

Molecular functions related to Granulomatous Myositis according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 tumor necrosis factor-activated receptor activity GO:0005031 8.62 TNFRSF1B TNFRSF8

Sources for Granulomatous Myositis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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