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MCID: GRW001

Growth Hormone Secreting Pituitary Adenoma malady
2 drugs, 22 genes, 3 tissues, 543 related diseases, 21 phenotypes, 21 articles, clinical trials.

Summaries for Growth Hormone Secreting Pituitary Adenoma

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44Wikipedia, 33OMIM, 22MalaCards
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Wikipedia: Acromegaly (pron.: /ˌækrɵˈmɛɡəli/; from Greek άκρος akros \"extreme\" or \"extremities\" and...44 more...

MalaCards: Growth Hormone Secreting Pituitary Adenoma, also known as growth hormone producing adenoma of the pituitary, is related to parathyroid adenoma and adrenal adenoma. An important gene associated with Growth Hormone Secreting Pituitary Adenoma is AIP (aryl hydrocarbon receptor interacting protein), and among its related pathways are Development Ligand-independent activation of ESR1 and ESR2 and Development A2A receptor signaling. The drugs octreotide acetate and octreotide and the compounds vapreotide and glucose have been mentioned in the context of this disorder. Affiliated tissues include colon, endothelial and pituitary, and related mouse phenotypes are respiratory system and endocrine/exocrine gland.

OMIM: 102200

Aliases & Descriptions for Growth Hormone Secreting Pituitary Adenoma

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6Disease Ontology, 43UMLS, 33OMIM, 27NCIt, 24MeSH, 40SNOMED-CT
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Aliases & Descriptions:

growth hormone secreting pituitary adenoma 6
growth hormone producing adenoma of the pituitary 6
growth hormone secreting adenoma of pituitary 6
pituitary adenoma, growth hormone-secreting 33
growth hormone-secreting pituitary adenoma 43
somatotroph adenoma (disorder) 6
pituitary eosinophilic adenoma 43
pituitary adenoma 43
adenoma 43

External Ids:

NCIt27 C7461
SNOMED-CT40 254957009

Related Diseases for Growth Hormone Secreting Pituitary Adenoma

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13GeneCards, 14GeneDecks
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Diseases related to growth hormone secreting pituitary adenoma by text searches and GeneDecks gene sharing:

(show top 50)    (show all 540)
idRelated DiseaseScoreTop Affiliating Genes
1parathyroid adenoma33.9MEN1, IGF1, GNAS, PRKAR1A
2adrenal adenoma33.4MEN1, CREB1, PRKAR1A
3thyroid adenoma32.9GNAS, CREB1, PRKAR1A
4cushing's syndrome32.5GH1, SST
5acth-secreting pituitary adenoma32.0GHRL, AIP, GAPDH
6aldosteronism30.9VEGFA, CGA, MEN1, IGF1, GH1, CREB1
7chromophobe adenoma30.2GH1, PRL
8renal carcinoma29.8VEGFA, MEN1, IGF1, GHRL, PRKAR1A
9sinusitis29.5VEGFA, CGA, IGF1, GH1, PRKAR1A, PRL
10functioning pituitary adenoma29.3CGA, IGF1, GNAS, GH1, GHR, SST
11tsh producing pituitary tumor29.1GH1, PRL
12fetal adenoma28.9GH1, GHRL, SSTR2, SSTR5, PRL
13polyposis28.6RB1, VEGFA, MEN1, IGF1, SST, PRKAR1A
14mccune albright syndrome28.3GNAS, GH1, PRL
15parathyroid carcinoma28.3RB1, MEN1
16adenoma28.1RB1, VEGFA, CGA, CGB, MEN1, IGF1
17pituitary adenoma28.1RB1, VEGFA, CGA, CGB, MEN1, IGF1
18primary hyperparathyroidism27.7MEN1, IGF1, GNAS, GH1, GHRL, AIP
19adrenal hyperplasia27.4CGA, CGB, IGF1, GNAS, GH1, PRKAR1A
20craniopharyngioma27.3CGA, IGF1, GH1, GHRL, PRL
21pituitary carcinoma27.2SST, SSTR2, PRL
22carney complex27.2MEN1, GNAS, GH1, AIP, PRKAR1A, PRL
23nelson syndrome27.2SST, PRL
24renal cell carcinoma27.1VEGFA, CGB, F2RL1, GNAS, GAPDH
25multiple endocrine neoplasia27.0MEN1, IGF1, GNAS, GH1, GHRHR, GHRL
26duodenitis26.8MEN1, IGF1, GHRL, SST, CREB1, PRL
27adenocarcinoma26.7RB1, VEGFA, CGA, CGB, MEN1, IGF1
28meningioma26.6RB1, VEGFA, MEN1, IGF1, F2RL1, GH1
29goiter26.5VEGFA, CGA, IGF1, GNAS, GH1, SST
30colon cancer26.5RB1, VEGFA, IGF1, F2RL1, GH1, SST
31hyperparathyroidism26.5VEGFA, MEN1, IGF1, GNAS, GH1, GHR
32papillary thyroid carcinoma26.4RB1, VEGFA, MEN1, GHRL, SST
33papilloma26.3RB1, VEGFA, MEN1, GAPDH
34thyroiditis26.2RB1, VEGFA, CGA, CGB, MEN1, IGF1
35colorectal cancer26.2RB1, VEGFA, CGA, CGB, IGF1, F2RL1
36hyperthyroidism26.1CGA, CGB, IGF1, GNAS, GH1, GHR
37hyperprolactinemia26.1CGA, CGB, IGF1, GNAS, GH1, SST
38vipoma26.0MEN1, GH1, SST
39prolactinoma26.0CGA, CGB, MEN1, IGF1, GNAS, GH1
40pituitary apoplexy25.9GH1, PRL
41adrenocortical hyperplasia25.9GNAS, CREB1, PRKAR1A
42graves' disease25.8CGA, IGF1, GNAS, SST, SSTR2, SSTR5
43paraganglioma25.6MEN1, SST, SSTR2, PRKAR1A
44acromegaly25.6VEGFA, CGB, MEN1, IGF1, GNAS, GH1
45prostatic hypertrophy25.5IGF1, F2RL1, PRL
46pituitary tumor25.4RB1, MEN1, IGF1, GNAS, GH1, GHR
47retinoblastoma25.4RB1, VEGFA, MEN1, IGF1, CREB1, GAPDH
48gigantism25.3MEN1, IGF1, GNAS, GH1, GHR, GHRHR
49pheochromocytoma25.2VEGFA, MEN1, GNAS, GHRL, SST, SSTR2
50ovarian hyperstimulation syndrome25.1VEGFA, CGA, F2RL1, CREB1

Graphical network of the top 20 diseases related to growth hormone secreting pituitary adenoma:



Graphical network of diseases related to growth hormone secreting pituitary adenoma

Clinical Features for Growth Hormone Secreting Pituitary Adenoma

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33OMIM
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Clinical features from OMIM: 102200

Drugs & Therapeutics for Growth Hormone Secreting Pituitary Adenoma

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4CenterWatch, 29NIH Clinical Center, 5ClinicalTrials, 43UMLS, 28NDF-RT
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Approved drugs:

Search CenterWatch for growth hormone secreting pituitary adenoma

Drug clinical trials:

Search ClinicalTrials for growth hormone secreting pituitary adenoma

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Search CenterWatch for growth hormone secreting pituitary adenoma

Inferred drug relations via UMLS/NDF-RT:

43 28 octreotide, octreotide acetate

Genetic Tests for Growth Hormone Secreting Pituitary Adenoma

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Anatomical Context for Growth Hormone Secreting Pituitary Adenoma

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22MalaCards
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MalaCards organs/tissues related to growth hormone secreting pituitary adenoma:

22
Colon, Endothelial, Pituitary

Phenotypes for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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25MGI
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MGI Mouse Phenotypes related to growth hormone secreting pituitary adenoma:

25 (show all 21)
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1respiratory system phenotypeMP:00053889.7PRKAR1A, CREM
2endocrine/exocrine gland phenotypeMP:00053799.3MEN1, GNAS, GHR, PRKAR1A
3embryogenesis phenotypeMP:00053809.3PRL, PRKAR1A, CREB1, AIP, MEN1
4immune system phenotypeMP:00053878.9PRL, PRKAR1A, GHR, GNAS, MEN1
5integument phenotypeMP:00107718.9PRL, AIP, GHRHR, GNAS, F2RL1, RB1
6tumorigenesisMP:00020068.4PRL, PRKAR1A, AIP, F2RL1, IGF1, MEN1
7reproductive system phenotypeMP:00053898.3PRL, PRKAR1A, CREM, GHRHR, GH1, MEN1
8liver/biliary system phenotypeMP:00053708.1PRL, CREM, AIP, GHR, GH1, MEN1
9limbs/digits/tail phenotypeMP:00053718.0RB1, VEGFA, GNAS, GHR, GHRHR
10digestive/alimentary phenotypeMP:00053818.0PRKAR1A, SSTR2, SST, GHSR, GHRL, MEN1
11skeleton phenotypeMP:00053907.9PRKAR1A, GHSR, GHRHR, GNAS, F2RL1, IGF1
12no phenotypic analysisMP:00030127.9SST, GHSR, GHRL, GNAS, F2RL1, VEGFA
13muscle phenotypeMP:00053697.6PRKAR1A, CREM, CREB1, GNAS, IGF1, MEN1
14adipose tissue phenotypeMP:00053757.3PRKAR1A, GHSR, GHRL, GHRHR, GHR, GH1
15nervous system phenotypeMP:00036317.2PRL, CREM, CREB1, SSTR2, GHRHR, GHR
16normal phenotypeMP:00028737.2RB1, VEGFA, IGF1, GNAS, GHRL, SST
17mortality/agingMP:00107686.5GAPDH, PRKAR1A, CREM, CREB1, GHR, GNAS
18behavior/neurological phenotypeMP:00053865.9SST, SSTR2, CREB1, CREM, PRL, GHSR
19cardiovascular system phenotypeMP:00053855.9SSTR2, CREB1, CREM, PRKAR1A, GAPDH, AIP
20growth/size phenotypeMP:00053785.1GHSR, AIP, SST, SSTR5, CREB1, PRKAR1A
21homeostasis/metabolism phenotypeMP:00053763.9GHSR, AIP, SST, SSTR2, SSTR5, CREB1

Publications for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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35PubMed
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Articles related to growth hormone secreting pituitary adenoma:

(show all 21)
idTitleAuthorsYearAffiliating Genes
1Expression of Ki-67, p53 and vascular endothelial gro wth factor (VEGF) concomitantly in growth hormone-secreting pituitary adenomas; which one has a role in tumor behavior ? (21196926)Yarman S.... Ince N.2010VEGFA
2Elevation of growth hormone secretagogue receptor typ e 1a mRNA expression in human growth hormone-secreting pituitary adenoma harbor ing G protein alpha subunit mutation. (20150876)Xu T.... Lei T.2010GNAS, GHSR, GHRL
3Low levels of raf kinase inhibitory protein in growth hormone-secreting pituitary adenomas correlate with poor response to octreotide treatment. (18230656)Fougner S.L.... Berg J.P.2008IGF1, SST, GH1
4Prognostic significance of the Ki-67 labeling index in growth hormone-secreting pituitary adenomas. (18460561)Fusco A.... De Marinis L.2008GH1
5Elevation of growth hormone-releasing hormone receptor messenger ribonucleic acid expression in growth hormone-secreting pituitary adenoma with Gsalpha protein mutation. (19029774)Sakai N.... Shibasaki T.2008GNAS, GHRHR
6MRI finding of simultaneous coexistence of growth hormone-secreting pituitary adenoma with intracranial meningioma and carotid artery aneurysms: report of a case. (17334927)Curto L.... Cannavo S.2007GH1
7A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report. (17411461)Mai P.L.... Greene M.H.2007PRKAR1A, MEN1
8Silent growth hormone secreting pituitary adenomas: IGF-1 is not sufficient to exclude growth hormone excess. (17270100)Kalavalapalli S.... Heald A.H.2007IGF1
9Tumor deletion mapping of chromosomal region 13q14 in 43 growth hormone secreting pituitary adenomas. (16388084)Donangelo I.... Gadelha M.R.2005RB1
10Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: the relationship with endogenous srif activity and response to octreotide. (15118275)Park C.... Park S.2004SSTR2, SSTR5, SST
11Somatostatin analogs in treatment of non-growth hormone-secreting pituitary adenomas. (12721508)Colao A.... Lombardi G.2003SSTR2, SST
12Medical management of growth hormone-secreting pituitary adenomas. (12675503)Racine M.S.... Barkan A.L.2002IGF1, GHR
13Expression of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein and inducible-cAMP early repressor genes in growth hormone-secreting pituitary adenomas with or without mutations of the Gsalpha gene. (11344215)Peri A.... Spada A.2001GAPDH, GNAS, CREB1
14Proliferation, vascular endothelial growth factor expression and cavernous sinus invasion in growth hormone secreting pituitary adenomas. (11214627)Iuchi T.... Yamaura A.2000VEGFA
15Detection of gsp oncogene in growth hormone-secreting pituitary adenomas and the study of clinical characteristics of acromegalic patients with gsp-positive pituitary tumors. (11189233)Shi Y.... Su C.1998GNAS, GH1
16Detection of growth hormone, prolactin and human beta-chorionic gonadotropin mRNA in growth hormone-secreting pituitary adenomas and in prolactin-secreting pituitary adenomas by in situ hybridization using a non-isotopic detection method. (8317187)Tallen G.... LA1decke D.K.1993PRL, GH1, CGB
17Transsphenoidal adenomectomy for growth hormone-secreting pituitary adenomas in acromegaly: outcome analysis and determinants of failure. (8421204)Tindall G.T.... Adams D.A.1993GH1
18Cytocidal effects of bromocriptine, somatostatin analog, and heat on growth hormone-secreting pituitary adenoma in vitro. (1571899)Kawamoto K.... Yano T.1992PRL, SST
19Detection of growth hormone, prolactin and human beta-chorionic gonadotropin messenger RNA in growth-hormone-secreting pituitary adenomas by in situ hybridization. (2058088)Uhlig H.... LA1decke D.K.1991PRL, CGA, GH1
20Differential response to aminergic stimuli and biological behavior of growth hormone secreting pituitary adenomas. (2107017)Fanghanel G.... Velasco F.1990PRL
21Prolactin gene expression in human growth hormone-secreting pituitary adenomas. (2338572)Nagaya T.... Matsui N.1990PRL

Expression for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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1BioGPS
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Expression patterns in normal tissues for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Pathways for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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10EMD Millipore, 41Thomson Reuters, 36QIAGEN, 38Reactome, 20KEGG
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Pathways related to growth hormone secreting pituitary adenoma according to GeneDecks:

(show all 25)
idPathwayScoreTop Affiliating Genes
1Development Ligand-independent activation of ESR1 and ESR21010.3PRKAR1A, GNAS
2Development A2A receptor signaling1010.2PRKAR1A, GNAS
3Beta-2 adrenergic-dependent CFTR expression419.9PRKAR1A, CREB1, GNAS
4Development_Hedgehog and PTH signaling pathways in bone and cartilage development419.9PRKAR1A, CREB1, GNAS
5Development Hedgehog and PTH signaling pathways in bone and cartilage development109.9GNAS, CREB1, PRKAR1A
6DREAM Repression and Dynorphin Expression369.8CREB1, CREM, PRKAR1A
7G-protein signaling_G-Protein alpha-s signaling cascades419.8PRKAR1A, CREB1, GNAS
8G-protein signaling G-Protein alpha-s signaling cascades109.8PRKAR1A, CREB1, GNAS
9Development_A2A receptor signaling419.8PRKAR1A, CREB1, GNAS
10Development_Ligand-independent activation of ESR1 and ESR2419.8IGF1, GNAS, PRKAR1A
11Development_A2B receptor- action via G-protein alpha s419.7PRKAR1A, CREB1, GNAS
12Development A2B receptor- action via G-protein alpha s109.7PRKAR1A, CREB1, GNAS
13GHRH Signaling369.7GH1, GHRHR, CREB1, PRKAR1A
14Transcription CREM signaling in testis109.7PRKAR1A, CREM, CREB1, GNAS
15Transcription_CREM signaling in testis419.7PRKAR1A, CREM, CREB1, GNAS
16Neurophysiological process Glutamate regulation of Dopamine D1A receptor signaling109.6PRKAR1A, CREB1, GNAS
17Development_Role of Activin A in cell differentiation and proliferation419.6PRKAR1A, CREB1, GNAS, CGA
18Development Role of Activin A in cell differentiation and proliferation109.6PRKAR1A, CREB1, GNAS, CGA
19Neurophysiological process_Glutamate regulation of Dopamine D1A receptor signaling419.5GNAS, CREB1, PRKAR1A
20G alpha (q) signalling events389.3GHSR, GHRL, F2RL1
21Growth Hormone Signaling369.1IGF1, GH1, GHR
22Selected targets of GCR-alpha109.1GHSR, GHR, CGA
23Activation of PKA through GPCR369.0PRKAR1A, CREM, CREB1, GH1, IGF1
24Nuclear Receptor Activation by Vitamin-A369.0IGF1, GH1, CREB1, PRKAR1A
25Neuroactive ligand-receptor interaction208.0CGA, PRL, SSTR5, SSTR2, GHSR, GHRHR

Compounds for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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32Novoseek , 9DrugBank, 18HMDB, 34PharmGKB, 42Tocris Bioscience
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Compounds related to growth hormone secreting pituitary adenoma according to GeneDecks:

(show top 50)    (show all 123)
idCompoundScoreTop Affiliating Genes
1vapreotide32 9 9 11.9SST, SSTR2, SSTR5, GHSR
2glucose32 9.5PRKAR1A, SSTR2, GHRHR, CGB, GAPDH, GHSR
3quinagolide32 9.4IGF1, GH1, SST, PRL
4epinephrine32 9 18 9 12.3CREB1, CGA, GHRL
5clomiphene citrate32 9.1IGF1, CGB, CGA, PRL, GH1
6estradiol32 9 18 9 12.0CGA, RB1, CGB, CREB1, PRL
7pyridostigmine32 9 9 11.0SST, IGF1, GHRL, GH1, PRL
8glutamate32 9.0GHRHR, PRKAR1A, CREM, GAPDH, GNAS, SST
9pirenzepine32 9 9 11.0SST, GHRL, GH1, IGF1
10acipimox32 8.9SST, IGF1, GHRL, GH1
11levodopa32 9 9 10.8GHR, GH1, CREB1, PRL
12naloxone32 34 9 9 11.7CREB1, SST, GHRL, CGA, PRL, GH1
13opiate32 8.7CGA, PRL, CREB1, F2RL1, GH1, GHRL
14buserelin32 9 9 10.7PRL, IGF1, CGA, SST
15leuprolide acetate32 8.6CGA, GH1, GHR, PRL, IGF1
16pegvisomant32 9 9 10.5IGF1, SST, GHRL, GHR, GH1
17hydrocortisone32 9 9 10.5IGF1, PRL, GH1, GHRL, GHSR, SST
18cabergoline32 9 9 10.3SST, GHR, GH1, IGF1, CGA, PRL
19androstenedione32 18 9.2CGA, IGF1, CGB, GHR, PRL, GH1
20clonidine32 9 9 10.2GHR, SST, PRL, IGF1, GH1, CGA
21dehydroepiandrosterone sulfate32 8.1PRL, CGA, IGF1, GH1, GHR, GHRL
22triiodothyronine32 8.1IGF1, PRL, GH1, GHR, CGA, GHRL
23gnrh32 8.0GHRL, CGB, GH1, IGF1, GNAS, CREB1
24arginine32 7.9GHR, SST, GHSR, GHRHR, GH1, GNAS
25dopamine32 9 18 9 10.9GNAS, F2RL1, CGA, SSTR5, CREB1, SSTR2
26norepinephrine32 9 18 9 10.9GH1, GNAS, F2RL1, GHRL, SST, CREB1
27ghrp32 7.8PRL, SST, GHSR, GHRL, GHRHR, GHR
28hexarelin32 7.8IGF1, PRL, SST, GHSR, GHRL, GHRHR
29bromocriptine32 9 9 9.8PRL, CREB1, CGA, SST, GHR, GH1
30forskolin32 42 9 9 10.8SSTR2, CGA, F2RL1, GNAS, CREM, PRKAR1A
31lanreotide32 7.8GHR, GH1, F2RL1, IGF1, SST, SSTR2
32testosterone32 9 18 9 10.7SST, CGB, GHR, PRL, CREB1, GHSR
33progesterone32 42 9 18 9 11.7GNAS, PRL, SSTR2, GHR, GH1, CGB
34thyroxine32 18 8.7IGF1, CGA, PRL, CGB, SST, GHRL
35adenylate32 7.4CGA, GAPDH, PRKAR1A, GNAS, GH1, GHRHR
36tamoxifen32 34 9 9 10.3GAPDH, PRL, SSTR2, GHR, GH1, CGA
37actinomycin d32 7.3GAPDH, IGF1, RB1, VEGFA, CGA, F2RL1
38thymidine32 18 8.2IGF1, SSTR5, SSTR2, MEN1, RB1, F2RL1
39paraffin32 7.2RB1, VEGFA, CGA, F2RL1, GH1, GHRL
40cyclic amp32 18 8.2CREM, CREB1, GHRL, GHRHR, GHR, GNAS
41acth32 6.9SST, SSTR5, GNAS, SSTR2, PRL, CREB1
42steroid32 6.8GHR, RB1, IGF1, PRL, CGA, GNAS
43ribonucleic acid32 6.8SSTR2, SSTR5, PRL, GAPDH, GHRL, GHRHR
44cycloheximide32 6.7F2RL1, CGA, VEGFA, GAPDH, CREB1, GH1
45vegf32 6.2CGB, GAPDH, RB1, VEGFA, CGA, MEN1
46octreotide32 42 9 9 9.2VEGFA, IGF1, GHR, GHRL, GHSR, SST
47serine32 5.8GAPDH, CREM, CREB1, GHSR, GHRL, GHR
48dexamethasone32 42 34 9 9 9.8PRL, PRKAR1A, VEGFA, F2RL1, GH1, GHRHR
49tyrosine32 5.7GHRL, IGF1, MEN1, RB1, SSTR2, VEGFA
50estrogen32 5.4GHSR, GHRL, GAPDH, PRL, CREB1, SSTR2

GO Terms for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

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12Gene Ontology
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Cellular components related to growth hormone secreting pituitary adenoma according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1secretory granuleGO:0301419.3VEGFA, GHRHR, GHRL
2extracellular regionGO:0055766.1VEGFA, PRL, SST, GHRL, GHR, GH1

Biological processes related to growth hormone secreting pituitary adenoma according to GeneDecks:

(show all 26)
idNameGO IDScoreTop Affiliating Genes
1somatostatin signaling pathwayGO:03817010.3SSTR5, SSTR2
2positive regulation of appetiteGO:03210010.1GHRL, GHSR
3positive regulation of growth hormone secretionGO:06012410.1GHRL, GHRHR
4negative regulation of tumor necrosis factor biosynthetic processGO:04253610.1GHRL, GHSR
5negative regulation of interleukin-6 biosynthetic processGO:04540910.1GHSR, GHRL
6water homeostasisGO:03010410.1IGF1, GHRHR
7growth hormone secretionGO:03025210.0GHSR, GHRL, GHRHR
8negative regulation of organ growthGO:04662110.0MEN1, CGA
9negative regulation of interleukin-1 beta productionGO:0326919.8GHSR, GHRL
10lactationGO:0075959.8GHRHR, CREB1, PRL
11positive regulation of phosphatidylinositol 3-kinase cascadeGO:0140689.7GH1, F2RL1, IGF1
12positive regulation of insulin-like growth factor receptor signaling pathwayGO:0435689.6IGF1, GH1, GHRHR, GHSR
13JAK-STAT cascade involved in growth hormone signaling pathwayGO:0603979.4GH1, GHR, PRL
14G-protein coupled receptor signaling pathwayGO:0071869.4SSTR5, SST, GHSR, GHRL, F2RL1
15growth hormone receptor signaling pathwayGO:0603969.4GH1, GHR
16cellular response to insulin stimulusGO:0328699.4GHR, GHRHR, GHSR
17hormone-mediated signaling pathwayGO:0097559.4GHSR, GHRL, GHR
18response to foodGO:0320949.3GHR, GHSR
19positive regulation of positive chemotaxisGO:0509279.3VEGFA, F2RL1
20negative regulation of cell proliferationGO:0082859.2SSTR5, SSTR2, SST, IGF1, MEN1
21positive regulation of tyrosine phosphorylation of Stat5 proteinGO:0425239.2GHR, GH1, IGF1
22regulation of multicellular organism growthGO:0400149.1PRL, GHR, IGF1
23positive regulation of peptidyl-tyrosine phosphorylationGO:0507318.6VEGFA, IGF1, GH1, GHR
24positive regulation of multicellular organism growthGO:0400188.5GH1, CREB1, GHSR, GHRL, GHRHR, GHR
25signal transductionGO:0071658.5PRKAR1A, CREM, CREB1, AIP, IGF1, CGB
26positive regulation of transcription from RNA polymerase II promoterGO:0459447.9CREB1, F2RL1, IGF1, MEN1, CGA, VEGFA

Molecular functions related to growth hormone secreting pituitary adenoma according to GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1growth hormone-releasing hormone receptor activityGO:01652010.1GHRHR, GHSR
2somatostatin receptor activityGO:0049949.8SSTR2, SSTR5
3prolactin receptor bindingGO:0051489.8GH1, PRL
4peptide hormone bindingGO:0170469.2GHSR, GHRHR, GHR
5hormone activityGO:0051798.6CGA, CGB, IGF1, GH1, SST, PRL
6protein bindingGO:0055155.1AIP, SSTR2, CREB1, CREM, PRKAR1A, GAPDH

Sources for Growth Hormone Secreting Pituitary Adenoma

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2CDC
11FMA
18HMDB
19ICD9CM
20KEGG
24MeSH
25MGI
27NCIt
28NDF-RT
31NINDS
32Novoseek
33OMIM
35PubMed
36QIAGEN
43UMLS
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