MCID: GRW001
MIFTS: 58

Growth Hormone Secreting Pituitary Adenoma malady

Endocrine category

Summaries for Growth Hormone Secreting Pituitary Adenoma

Sources:
64Wikipedia, 47OMIM, 33MalaCards
See all sources

Fully expand this MalaCard

Export this MalaCard
Wikipedia:64 Acromegaly (/ˌækrɵˈmɛɡəli/; from Greek άκρος akros \"extreme\" or \"extremities\" and... more...

MalaCards: Growth Hormone Secreting Pituitary Adenoma, also known as somatotroph adenoma, is related to adenoma and acromegaly. An important gene associated with Growth Hormone Secreting Pituitary Adenoma is AIP (aryl hydrocarbon receptor interacting protein), and among its related pathways are Glycoprotein hormones and Development Prolactin receptor signaling. The compounds vapreotide and dehydroepiandrosterone sulfate have been mentioned in the context of this disorder. Affiliated tissues include skin, colon and thyroid, and related mouse phenotypes are adipose tissue and endocrine/exocrine gland.

Description from OMIM:47 102200

Aliases & Classifications for Growth Hormone Secreting Pituitary Adenoma

Sources:
8Disease Ontology, 22GTR, 47OMIM, 61UMLS, 35MeSH, 57SNOMED-CT, 40NCIt
See all sources

Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Endocrine


Aliases & Descriptions:

growth hormone secreting pituitary adenoma 8
somatotroph adenoma 8 22
growth hormone producing adenoma of the pituitary 8
growth hormone secreting adenoma of pituitary 8
pituitary adenoma, growth hormone-secreting 47
growth hormone-secreting pituitary adenoma 61


External Ids:

Disease Ontology8 DOID:6255
MeSH35 D049912
SNOMED-CT57 254957009
NCIt40 C7461
OMIM47 102200

Related Diseases for Growth Hormone Secreting Pituitary Adenoma

Sources:
17GeneCards, 18GeneDecks
See all sources

Diseases related to Growth Hormone Secreting Pituitary Adenoma via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show top 50)    (show all 173)
idRelated DiseaseScoreTop Affiliating Genes
1adenoma31.8F2RL1, GNAS, CREB1, AIP, IGF1, SST
2acromegaly30.7GNAS, AIP, IGF1, SST, SSTR2, SSTR5
3thyroid adenoma30.5GNAS, PRKAR1A
4adenocarcinoma30.5CREB1, MEN1, CGB, GHR, GHRL, SSTR2
5pituitary tumors30.4GNAS, MEN1, GHRHR, GHR, AIP, IGF1
6prolactinoma30.4AIP, IGF1, SST, SSTR2, SSTR5, PRKAR1A
7amenorrhea30.2IGF1, PRL
8somatostatin analog10.6
9moyamoya disease10.3
10mixed cell adenoma10.3
11papillary carcinoma10.3
12intracranial aneurysm10.3
13aortitis10.3
14gangliocytoma10.3
15n syndrome10.3
16papillary adenoma10.3
17short syndrome10.3
18familial renal cell carcinoma10.3
19headache10.3
20silent pituitary adenoma10.3
21choristoma10.1
22pituitary hypoplasia10.0GHRHR
23goiter10.0GNAS
24pseudohypoparathyroidism10.0GNAS
25osteomalacia10.0GNAS
26irritable bowel syndrome10.0F2RL1
27hyperinsulinemic hypoglycemia10.0SST
28eating disorder10.0GHRL
29thyroiditis10.0CGA
30hypogonadotropism10.0PRL
31diabetes insipidus10.0PRL
32bulimia nervosa10.0GHRL
33ovarian cancer10.0CGB, SSTR2
34myocardial infarction10.0GHRL
35hepatitis10.0GHR
36hypoparathyroidism10.0PRKAR1A
37pancreatitis10.0SST, F2RL1
38duodenum cancer10.0SST
39lipodystrophy10.0GHR
40somatostatinoma10.0SSTR2, SST
41ileus10.0GHRL
42liver cirrhosis10.0GHR
43pancreatic islet cell tumors10.0MEN1, SST
44hypertension10.0IGF1
45dysgerminoma10.0CGA
46sarcoma10.0SSTR2, CGB
47dyspepsia10.0GHRL
48isolated growth hormone deficiency type 1b10.0GH1, GHRHR
49hyperparathyroidism10.0PRKAR1A, MEN1
50acanthosis nigricans10.0IGF1

Graphical network of the top 20 diseases related to Growth Hormone Secreting Pituitary Adenoma:



Diseases related to growth hormone secreting pituitary adenoma

Clinical Features for Growth Hormone Secreting Pituitary Adenoma

Sources:
47OMIM
See all sources

Clinical features from OMIM:

102200

Clinical synopsis from OMIM:

102200

Drugs & Therapeutics for Growth Hormone Secreting Pituitary Adenoma

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
See all sources

Approved drugs:

Search CenterWatch for Growth Hormone Secreting Pituitary Adenoma

Drug clinical trials:

Search ClinicalTrials for Growth Hormone Secreting Pituitary Adenoma

Search NIH Clinical Center for Growth Hormone Secreting Pituitary Adenoma

Search CenterWatch for Growth Hormone Secreting Pituitary Adenoma

Genetic Tests for Growth Hormone Secreting Pituitary Adenoma

Sources:
22GTR
See all sources

Genetic tests related to Growth Hormone Secreting Pituitary Adenoma:

id Genetic test Affiliating Genes
1 Somatotroph Adenoma22

Anatomical Context for Growth Hormone Secreting Pituitary Adenoma

Sources:
33MalaCards
See all sources

MalaCards organs/tissues related to Growth Hormone Secreting Pituitary Adenoma:

33
Skin, Colon, Thyroid, B cells, Endothelial, Pituitary

Animal Models for Growth Hormone Secreting Pituitary Adenoma or affiliated genes

Sources:
37MGI, 28inGenious Targeting Laboratory
See all sources

Publications for Growth Hormone Secreting Pituitary Adenoma

Sources:
51PubMed
See all sources

Articles related to Growth Hormone Secreting Pituitary Adenoma:

(show top 50)    (show all 81)
idTitleAuthorsYear
1
Growth hormone secreting pituitary adenoma associated with Rathke's cleft cyst. (22824691)
2012
2
Neuroendocrine tumor of unknown origin metastasizing to a growth hormone-secreting pituitary adenoma. (22120409)
2012
3
Moyamoya syndrome following growth hormone-secreting pituitary adenoma. (22592188)
2012
4
Ectopic growth hormone-secreting pituitary adenoma involving the clivus treated with octreotide: role of magnetic resonance imaging in the diagnosis and clinical follow-up. (22990736)
2012
5
Transformation of a microprolactinoma into a mixed growth hormone and prolactin-secreting pituitary adenoma. (22654846)
2011
6
MGMT immunoexpression in growth hormone-secreting pituitary adenomas and its correlation with Ki-67 labeling index and cytokeratin distribution pattern. (21792693)
2011
7
Tumor volume of growth hormone-secreting pituitary adenomas during treatment with pegvisomant: a prospective multicenter study. (19965922)
2010
8
Expression of Ki-67, p53 and vascular endothelial growth factor (VEGF) concomitantly in growth hormone-secreting pituitary adenomas; which one has a role in tumor behavior ? (21196926)
2010
9
Elevation of growth hormone secretagogue receptor type 1a mRNA expression in human growth hormone-secreting pituitary adenoma harboring G protein alpha subunit mutation. (20150876)
2010
10
Growth hormone- secreting pituitary adenomas: from molecular basis to treatment options in acromegaly. (20234189)
2010
11
The role of stereotactic radiotherapy in patients with growth hormone-secreting pituitary adenoma. (18413424)
2008
12
Low levels of raf kinase inhibitory protein in growth hormone-secreting pituitary adenomas correlate with poor response to octreotide treatment. (18230656)
2008
13
Expression of vascular endothelial growth factor in growth hormone-secreting pituitary adenomas: special reference to the octreotide treatment. (18953743)
2008
14
Prognostic significance of the Ki-67 labeling index in growth hormone-secreting pituitary adenomas. (18460561)
2008
15
Short-lasting, unilateral neuralgiform headache attacks with conjunctival injection and tearing syndrome treated successfully with transsphenoidal resection of a growth hormone-secreting pituitary adenoma. (18590441)
2008
16
A possible new syndrome with growth-hormone secreting pituitary adenoma, colonic polyposis, lipomatosis, lentigines and renal carcinoma in association with familial testicular germ cell malignancy: A case report. (17411461)
2007
17
Silent growth hormone secreting pituitary adenomas: IGF-1 is not sufficient to exclude growth hormone excess. (17270100)
2007
18
Expression of p53, Ki-67 and c-erb B2 in growth hormone-and/or prolactin-secreting pituitary adenomas. (16622555)
2006
19
Acromegaly and somatotroph hyperplasia with adenomatous transformation due to pituitary metastasis of a growth hormone-releasing hormone-secreting pulmonary endocrine carcinoma. (16968791)
2006
20
Effect of preoperative use of long-acting octreotide on growth hormone secreting pituitary adenoma and transsphenoidal surgery. (15844307)
2005
21
Expression of the antiapoptotic gene seladin-1 and octreotide-induced apoptosis in growth hormone-secreting and nonfunctioning pituitary adenomas. (16091489)
2005
22
The novel somatostatin analog SOM230 is a potent inhibitor of hormone release by growth hormone- and prolactin-secreting pituitary adenomas in vitro. (15070915)
2004
23
Stereotactic conformal radiotherapy in patients with growth hormone-secreting pituitary adenoma. (15234043)
2004
24
Somatostatin (SRIF) receptor subtype 2 and 5 gene expression in growth hormone-secreting pituitary adenomas: the relationship with endogenous srif activity and response to octreotide. (15118275)
2004
25
Sarcomatous change after sellar irradiation in a growth hormone-secreting pituitary adenoma. (14672272)
2003
26
Characterization of the intracellular mechanisms mediating somatostatin and lanreotide inhibition of DNA synthesis and growth hormone release from dispersed human GH-secreting pituitary adenoma cells in vitro. (12807513)
2003
27
Somatostatin analogs in treatment of non-growth hormone-secreting pituitary adenomas. (12721508)
2003
28
Growth hormone-secreting pituitary adenoma associated with primary moyamoya disease--case report. (12924597)
2003
29
Medical management of growth hormone-secreting pituitary adenomas. (12675503)
2002
30
Expression of cyclic adenosine 3',5'-monophosphate (cAMP)-responsive element binding protein and inducible-cAMP early repressor genes in growth hormone-secreting pituitary adenomas with or without mutations of the Gsalpha gene. (11344215)
2001
31
Transsphenoidal surgery and adjuvant gamma knife treatment for growth hormone-secreting pituitary adenoma. (11780899)
2001
32
Proliferation, vascular endothelial growth factor expression and cavernous sinus invasion in growth hormone secreting pituitary adenomas. (11214627)
2000
33
Osseous metaplasia in a growth hormone-secreting pituitary adenoma. (10442463)
1999
34
A functional thyrotropin- and growth hormone-secreting pituitary adenoma with a ultrastructurally monomorphic feature: a case study. (9700474)
1998
35
Detection of gsp oncogene in growth hormone-secreting pituitary adenomas and the study of clinical characteristics of acromegalic patients with gsp-positive pituitary tumors. (11189233)
1998
36
Acute and chronic effects of octreotide on thyroid axis in growth hormone-secreting and clinically non-functioning pituitary adenomas. (7655643)
1995
37
Growth hormone secreting pituitary adenoma: Clinical aspects and surgical outcome. (17587934)
1995
38
Results of the lateral rhinotomy approach in transsphenoidal microsurgery for growth hormone-secreting pituitary adenoma. (8719832)
1995
39
Growth hormone-prolactin-thyrotropin-secreting pituitary adenoma in atypical McCune-Albright syndrome with functionally normal Gs alpha protein. (7962285)
1994
40
Hormonal and radiological effects of megavoltage radiotherapy in patients with growth hormone-secreting pituitary adenoma. (8258643)
1993
41
Detection of growth hormone, prolactin and human beta-chorionic gonadotropin mRNA in growth hormone-secreting pituitary adenomas and in prolactin-secreting pituitary adenomas by in situ hybridization using a non-isotopic detection method. (8317187)
1993
42
Coexistence of growth hormone-secreting pituitary adenoma and intracranial meningioma: a case report and review of the literature. (8282967)
1993
43
Light and electron microscopic observation of the same mammosomatotroph cell in a mixed growth hormone- and prolactin-secreting pituitary adenoma--case report. (7685856)
1993
44
Transsphenoidal adenomectomy for growth hormone-secreting pituitary adenomas in acromegaly: outcome analysis and determinants of failure. (8421204)
1993
45
Cytocidal effects of bromocriptine, somatostatin analog, and heat on growth hormone-secreting pituitary adenoma in vitro. (1571899)
1992
46
Detection of growth hormone, prolactin and human beta-chorionic gonadotropin messenger RNA in growth-hormone-secreting pituitary adenomas by in situ hybridization. (2058088)
1991
47
Prolactin gene expression in human growth hormone-secreting pituitary adenomas. (2338572)
1990
48
Intrasellar gangliocytoma containing gastrin and growth hormone-releasing hormone associated with a growth hormone-secreting pituitary adenoma. (2512034)
1989
49
Malignant growth hormone-secreting pituitary adenoma with hematogenous dural metastasis: case report. (3047593)
1988
50
Growth hormone-secreting pituitary adenoma in uniovular twin brothers: case report. (7193813)
1981

Genetic Variations for Growth Hormone Secreting Pituitary Adenoma

Expression for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
See all sources
Expression patterns in normal tissues for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Search GEO for disease gene expression data for Growth Hormone Secreting Pituitary Adenoma.

Pathways for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Sources:
54Reactome, 38NCBI BioSystems Database, 12EMD Millipore, 30KEGG, 52QIAGEN
See all sources

Pathways related to Growth Hormone Secreting Pituitary Adenoma according to GeneCards/GeneDecks:

(show all 27)
idSuper pathways (with members indented)ScoreTop Affiliating Genes
1
Hide members
10.0CGA, CGB
2
Development Prolactin receptor signaling
Hide members
9.9CREB1, PRL
3
Hide members
9.8GHSR, SSTR5, SSTR2, F2RL1
4
Development A2B receptor- action via G-protein alpha s
Hide members
9.7PRKAR1A, CREB1, GNAS
59.7PRKAR1A, CREB1, GNAS
6
Development Hedgehog and PTH signaling pathways in bone and cartilage development
Hide members
9.7GNAS, CREB1, PRKAR1A
79.7GNAS, CREB1, PRKAR1A
8
Hide members
9.7PRL, GH1, GHR
9
Hide members
9.7GHRL, CGB, CGA
109.7GHSR, GHR, CGA
119.7GNAS, CREB1, CGA
129.6PRL, CGA, CREB1
139.6GHR, GH1, IGF1
149.6GNAS, CGA, IGF1
15
Hide members
9.6CREB1, GHRHR, GH1, PRKAR1A
16
Hide members
9.5CREB1, GHSR, GHRL, F2RL1
17
Hide members
9.4PRL, GH1, GHR, CREB1
18
Translation Insulin regulation of translation
Hide members
9.4IGF1, PRKAR1A, GH1, GHR
19
Development Ligand-independent activation of ESR1 and ESR2
Hide members
9.4IGF1, PRKAR1A, CREB1, GNAS
209.2SST, SSTR2, PRKAR1A, CREB1, CREM
21
Hide members
9.1IGF1, PRL, GH1, GHR, CREB1
229.1IGF1, PRL, GH1, GHR, CREB1
23
Hide members
9.0GNAS, CREM, CREB1, CGA, PRKAR1A
24
Hide members
9.0CREM, CREB1, GH1, PRKAR1A, IGF1
25
Hide members
8.8CREB1, GHR, GH1, PRL, PRKAR1A, IGF1
26
Hide members
7.8GNAS, CGA, GHRHR, GHR, GHSR, GHRL
27
Hide members
6.7F2RL1, GNAS, CREB1, MEN1, CGA, GHRHR

Compounds for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Sources:
29IUPHAR, 45Novoseek, 11DrugBank, 60Tocris Bioscience, 50PharmGKB, 24HMDB, 2BitterDB
See all sources

Compounds related to Growth Hormone Secreting Pituitary Adenoma according to GeneCards/GeneDecks:

(show top 50)    (show all 151)
idCompoundScoreTop Affiliating Genes
1vapreotide29 45 1112.1SST, SSTR2, SSTR5, GHSR
2dehydroepiandrosterone sulfate4510.1CGA, GHR, GH1
3cyn 154806609.9SSTR2, SST, SSTR5
4glucose459.9CGB, GHRL, SSTR2, IGF1
5ghrp-645 2910.9GHSR, SST, GHRL
6quinagolide459.9IGF1, SST, PRL, GH1
7somatuline459.9GH1, SST, IGF1
8dexamethasone45 50 29 1112.8GHSR, GHRL, GHRHR, GH1, CREB1
9acipimox45 2910.7GH1, SST, IGF1, GHRL
10pasireotide45 1110.6SST, SSTR2, SSTR5
11pyridostigmine45 1110.6GHRL, GH1, SST, IGF1, PRL
12pirenzepine45 29 1111.6SST, IGF1, GH1, GHRL
13buserelin45 29 1111.6IGF1, SST, PRL, CGA
14clomiphene citrate459.6CGA, IGF1, CGB, GH1, PRL
15pegvisomant45 1110.5SST, GHRL, IGF1, GHR, GH1
16bromocriptine29 45 1111.5SST, CREB1, CGA, PRL, GHR
17norepinephrine45 11 2411.5GNAS, CGA, PRL, F2RL1, CREB1
18forskolin45 50 1111.5SSTR2, PRKAR1A, GHSR, CREB1, CREM, GHRHR
19leuprolide acetate459.5IGF1, CGA, GHR, GH1, PRL
20naloxone45 50 29 1112.4CGA, SST, PRL, CREB1, GHRL, GH1
21c-peptide459.4SST, GHR, GHRL, GH1, IGF1
22estradiol45 11 2411.4GHR, CGA, CREB1, CGB, PRL, GHSR
23opiate459.3F2RL1, PRL, GH1, GHRL, CGA, CREB1
24hydrocortisone45 2 60 1112.3IGF1, SST, GHSR, GHRL, PRL, GH1
25cabergoline29 45 1111.3PRL, SST, IGF1, GH1, GHR, CGA
26clonidine45 29 1111.2IGF1, SST, PRL, GH1, GHR, CGA
27androstenedione45 2410.2GH1, GHR, CGB, CGA, PRL, IGF1
28levodopa45 1110.2IGF1, SST, GH1, CREB1, GHR, PRL
29glutamate459.1PRKAR1A, GHRL, GHRHR, CGA, CREM, GNAS
30triiodothyronine459.1IGF1, PRL, GH1, GHRL, GHR, CGA
31hexarelin45 2910.0GHRHR, IGF1, SST, PRL, GH1, GHRL
32ghrp459.0GHSR, GHR, GHRHR, GHRL, GH1, PRL
33lanreotide45 299.9SSTR5, SSTR2, F2RL1, IGF1, SST, PRL
34vitamin d458.8MEN1, GHR, GHRL, PRKAR1A, IGF1, CGA
35serine458.8F2RL1, CGA, GNAS, CREM, MEN1, GH1
36thyroxine45 249.8SST, IGF1, GHRL, CGB, CGA, GH1
37dopamine45 29 11 2411.8GNAS, CREB1, GHR, F2RL1, IGF1, SSTR2
38thymidine45 249.7IGF1, SSTR2, SSTR5, GH1, GHRL, MEN1
39progesterone45 60 29 11 2412.5PRL, SSTR2, IGF1, GH1, CGA, CGB
40vegf458.5GHRL, GH1, SSTR2, SST, IGF1, F2RL1
41steroid458.4CGA, CREB1, GNAS, GHR, GHSR, GH1
42octreotide45 60 29 1111.4GNAS, GHR, GHSR, GHRL, GH1, PRL
43cyclic amp45 249.4PRKAR1A, CGB, GHRL, CREB1, GHR, GHRHR
44acth458.3GNAS, IGF1, SST, CREB1, GHR, GHSR
45ribonucleic acid458.3IGF1, SSTR2, PRL, GH1, GHRL, GHSR
46testosterone45 60 11 2411.3GHSR, GHR, CGB, GHRL, PRL, CGA
47adenylate458.3GHSR, CREB1, SST, PRKAR1A, CREM, GNAS
48gnrh458.2CGB, GHR, GHRL, GH1, PRL, SSTR2
49arginine458.0F2RL1, CGA, IGF1, SST, PRL, PRKAR1A
50tyrosine457.6F2RL1, IGF1, SSTR2, GNAS, CREM, CREB1

GO Terms for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

Sources:
16Gene Ontology
See all sources

Cellular components related to Growth Hormone Secreting Pituitary Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1plasma membraneGO:0058868.3GHRHR, GHR, GHSR, PRKAR1A, SSTR5, SSTR2
2extracellular regionGO:0055767.9IGF1, GNAS, CGA, CGB, GHR, GHRL

Biological processes related to Growth Hormone Secreting Pituitary Adenoma according to GeneCards/GeneDecks:

(show all 35)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of appetiteGO:03210010.4GHRL, GHSR
2negative regulation of tumor necrosis factor biosynthetic processGO:04253610.4GHRL, GHSR
3negative regulation of interleukin-6 biosynthetic processGO:04540910.3GHRL, GHSR
4negative regulation of interleukin-1 beta productionGO:03269110.3GHRL, GHSR
5water homeostasisGO:03010410.3GHRHR, IGF1
6growth hormone secretionGO:03025210.3GHRL, GHSR, GHRHR
7positive regulation of growth hormone secretionGO:06012410.3GHRHR, GHRL
8Type I pneumocyte differentiationGO:06050910.2IGF1, CREB1
9growth hormone receptor signaling pathwayGO:06039610.2GHR, GH1
10response to foodGO:03209410.2GHR, GHSR
11negative regulation of organ growthGO:04662110.2MEN1, CGA
12lactationGO:00759510.1CREB1, GHRHR, PRL
13cellular response to insulin stimulusGO:03286910.1GHSR, GHR, GHRHR
14response to nutrientGO:00758410.1PRL, SSTR2, SST
15hormone-mediated signaling pathwayGO:00975510.1GHRL, GHSR, GHR
16JAK-STAT cascade involved in growth hormone signaling pathwayGO:06039710.1GHR, GH1, PRL
17adult feeding behaviorGO:00834310.1GHRL, GHSR
18positive regulation of phosphatidylinositol 3-kinase cascadeGO:01406810.1F2RL1, IGF1, GH1
19actin polymerization or depolymerizationGO:00815410.0GHRL, GHSR
20positive regulation of tyrosine phosphorylation of Stat5 proteinGO:04252310.0GHR, GH1, IGF1
21response to estradiol stimulusGO:03235510.0GHR, GH1, PRL
22positive regulation of osteoblast differentiationGO:04566910.0GNAS, MEN1, IGF1
23positive regulation of insulin-like growth factor receptor signaling pathwayGO:04356810.0GHRHR, GHSR, GH1, IGF1
24regulation of insulin secretionGO:05079610.0GNAS, PRKAR1A, SSTR5
25regulation of multicellular organism growthGO:0400149.9IGF1, PRL, GHR
26positive regulation of peptidyl-tyrosine phosphorylationGO:0507319.9GHR, GH1, IGF1
27G-protein coupled receptor signaling pathwayGO:0071869.8GHSR, GHRL, SSTR5, SST, F2RL1
28insulin-like growth factor receptor signaling pathwayGO:0480099.8IGF1, GHR
29cell-cell signalingGO:0072679.8SST, SSTR2, CGB, CGA
30negative regulation of cell proliferationGO:0082859.7IGF1, SST, SSTR2, SSTR5, MEN1
31positive regulation of JAK-STAT cascadeGO:0464279.7PRL, GH1
32positive regulation of multicellular organism growthGO:0400189.5GH1, GHRL, GHSR, GHR, GHRHR, CREB1
33response to drugGO:0424939.4GNAS, CREB1, PRL, SST
34positive regulation of transcription from RNA polymerase II promoterGO:0459449.0CREM, CREB1, MEN1, CGA, IGF1, F2RL1
35signal transductionGO:0071658.9CREM, CREB1, CGA, CGB, PRKAR1A, IGF1

Molecular functions related to Growth Hormone Secreting Pituitary Adenoma according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1somatostatin receptor activityGO:00499410.1SSTR2, SSTR5
2prolactin receptor bindingGO:0051489.9PRL, GH1
3peptide hormone bindingGO:0170469.9GHRHR, GHR, GHSR
4growth hormone-releasing hormone receptor activityGO:0165209.8GHSR, GHRHR
5hormone activityGO:0051799.1IGF1, SST, PRL, GH1, CGB, CGA
6protein bindingGO:0055157.0GNAS, CREM, CREB1, MEN1, CGA, GHRHR

Products for genes affiliated with Growth Hormone Secreting Pituitary Adenoma

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Growth Hormone Secreting Pituitary Adenoma

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet