MCID: GLL022
MIFTS: 61

Guillain-Barre Syndrome

Categories: Rare diseases, Neuronal diseases, Genetic diseases, Immune diseases

Aliases & Classifications for Guillain-Barre Syndrome

MalaCards integrated aliases for Guillain-Barre Syndrome:

Name: Guillain-Barre Syndrome 12 49 24 36 51 40 41 14 69 49 24 50
Fisher Syndrome 24 50 36
Acute Inflammatory Demyelinating Polyneuropathy 49 69
Acute Inflammatory Polyneuropathy 49 24
Gbs 49 24
Acute Inflammatory Demyelinating Polyradiculoneuropathy 49
Acute Autoimmune Peripheral Neuropathy 49
Landry-Guillain-Barre-Strohl Syndrome 49
Acute Immune-Mediated Polyneuropathy 49
Acute Postinfectious Polyneuropathy 12
Guillain-Barré-Strohl Syndrome 49
Landry-Guillain-Barre Syndrome 24
Acute Inflammatory Neuropathy 49
Acute Infectious Polyneuritis 24
Acute Infective Polyneuritis 12
Post-Infectious Polyneuritis 12
Landry's Ascending Paralysis 49
Postinfectious Polyneuritis 12
Post-Infective Polyneuritis 49
Miller Fisher Syndrome 69
Infectious Neuronitis 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12842
ICD10 32 G61.0
MeSH 41 D020275
NCIt 46 C116345

Summaries for Guillain-Barre Syndrome

MedlinePlus : 40 Guillain-Barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (PNS). The PNS nerves connect your brain and spinal cord with the rest of your body. Damage to these nerves makes it hard for them to transmit signals. As a result, your muscles have trouble responding to your brain. No one knows what causes the syndrome. Sometimes it is triggered by an infection, surgery, or a vaccination. The first symptom is usually weakness or a tingling feeling in your legs. The feeling can spread to your upper body. In severe cases, you become almost paralyzed. This is life-threatening. You might need a respirator to breathe. Symptoms usually worsen over a period of weeks and then stabilize. Guillain-Barre can be hard to diagnose. Possible tests include nerve tests and a spinal tap. Most people recover. Recovery can take a few weeks to a few years. Treatment can help symptoms, and may include medicines or a procedure called plasma exchange. NIH: National Institute of Neurological Disorders and Stroke

MalaCards based summary : Guillain-Barre Syndrome, also known as fisher syndrome, is related to miller fisher syndrome and peripheral nervous system disease, and has symptoms including ophthalmoplegia, cerebellar ataxia and sleeplessness. An important gene associated with Guillain-Barre Syndrome is PMP22 (Peripheral Myelin Protein 22), and among its related pathways/superpathways are 4-1BB Pathway and NF-kappaB Signaling. The drugs Vaccines and Antibodies have been mentioned in the context of this disorder. Affiliated tissues include testes, brain and spinal cord, and related phenotypes are Decreased viability and Decreased viability

NIH Rare Diseases : 49 Guillain-Barré syndrome (GBS) is a rare syndrome in which the body’s immune system attacks part of the peripheral nervous system. The peripheral nervous system carries signals from the brain to the muscles. Symptoms of GBS include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all (paralysis). The exact cause of Guillain-Barré syndrome is unknown. In most cases, GBS occurs a few days or weeks after symptoms of a viral infection. In rare cases, GBS may run in families. A diagnosis of GBS is suspected when a person has symptoms suggestive of the syndrome. A variety of tests, including a spinal tap, may be completed to confirm the diagnosis. Treatment options may include plasma exchange (plasmapheresis) and immunoglobulin therapy.  Last updated: 12/14/2017

NINDS : 50 Miller Fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. Like Guillain-Barré syndrome, symptoms may be preceded by a viral illness. Additional symptoms include generalized muscle weakness and respiratory failure. The majority of individuals with Miller Fisher syndrome have a unique antibody that characterizes the disorder.

Disease Ontology : 12 An autoimmune disease of peripheral nervous system that causes body's immune system to attack part of the peripheral nervous system.

Wikipedia : 72 Guillain–Barré syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system damaging the... more...

Related Diseases for Guillain-Barre Syndrome

Diseases in the Guillain-Barre Syndrome family:

Guillain-Barre Syndrome, Familial

Diseases related to Guillain-Barre Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 281)
# Related Disease Score Top Affiliating Genes
1 miller fisher syndrome 33.2 CD40LG TNF
2 peripheral nervous system disease 31.8 CD40LG MPZ PMP22
3 burns 30.4 ALB TNF
4 demyelinating polyneuropathy 30.4 ALB HP PMP22
5 hepatitis e 30.2 ALB CD40LG TNF
6 chronic inflammatory demyelinating polyradiculoneuropathy 30.1 ALB MBP MPZ PMP22
7 polyneuropathy 29.9 CD40LG MBP MPZ PMP22
8 purpura 29.7 CD40LG CD79A TNF
9 glomerulonephritis 29.5 ALB CD40LG CD79A
10 meningoencephalitis 29.4 ALB CD40LG CD79A MBP
11 multiple sclerosis 29.3 HLA-DQB1 MBP MPZ TNF TNFRSF1A
12 polyradiculoneuropathy 29.1 ALB MBP MPZ PMP2 PMP22 TNFRSF1A
13 celiac disease 1 28.5 ALB CD40LG CD79A HLA-DQB1 HP TNF
14 systemic lupus erythematosus 28.3 ALB CD40LG CD79A HLA-DQB1 TNF TNFRSF1A
15 guillain-barre syndrome, familial 12.5
16 pharyngeal-cervical-brachial variant of guillain-barré syndrome 12.3
17 paraparetic variant of guillain-barré syndrome 12.3
18 chronic inflammatory demyelinating polyneuropathy 11.7
19 autonomic dysfunction 11.5
20 dysautonomia 11.5
21 neuropathy, hereditary sensory and autonomic, type iii 11.2
22 acute flaccid myelitis 11.2
23 zika virus infection 11.2
24 hereditary neuropathy with liability to pressure palsy 10.6 MPZ PMP22
25 charcot-marie-tooth neuropathy type 1 10.6 MPZ PMP22
26 foot drop 10.6 MPZ PMP22
27 charcot-marie-tooth disease, demyelinating, type 1f 10.6 MPZ PMP22
28 ostertagiasis 10.5 ALB CD79A
29 dermatitis, atopic, 3 10.5 ALB CD79A
30 skin sarcoidosis 10.5 TNF TNFRSF1B
31 granulomatous dermatitis 10.5 TNF TNFRSF1B
32 farmer's lung 10.5 CD79A TNF
33 scleral disease 10.5 TNF TNFRSF1B
34 orthostatic proteinuria 10.5 ALB CD79A
35 pustulosis of palm and sole 10.5 TNF TNFRSF1B
36 congenital hypomyelination neuropathy 10.5 MBP MPZ PMP22
37 beryllium disease 10.4 HLA-DQB1 TNF
38 root caries 10.4 ALB CD79A
39 hereditary neuropathies 10.4 MBP MPZ PMP22
40 pelizaeus-merzbacher disease 10.4 MBP MPZ PMP22
41 chronic beryllium disease 10.4 HLA-DQB1 TNF
42 optic neuritis 10.4 MBP MPZ TNF
43 marasmus 10.4 ALB CD79A
44 autoimmune pancreatitis 10.4 HLA-DQB1 TNF
45 peroneal neuropathy 10.4 TNF TNFRSF1B
46 protein-energy malnutrition 10.4 ALB CD79A TNF
47 keratoconjunctivitis sicca 10.4 ALB CD79A TNF
48 obstructive jaundice 10.4 ALB CD79A TNF
49 influenza 10.4
50 end stage renal failure 10.4 ALB CD79A TNF

Graphical network of the top 20 diseases related to Guillain-Barre Syndrome:



Diseases related to Guillain-Barre Syndrome

Symptoms & Phenotypes for Guillain-Barre Syndrome

UMLS symptoms related to Guillain-Barre Syndrome:


ophthalmoplegia, cerebellar ataxia, sleeplessness, vertigo/dizziness, chronic pain, tremor, syncope, seizures, sciatica, pain, neuralgia, headache, back pain

GenomeRNAi Phenotypes related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

25
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability GR00381-A-1 9.1 CD79A HLA-DQB1 MPZ
2 Decreased viability GR00381-A-3 9.1 CD79A HLA-DQB1 MPZ

MGI Mouse Phenotypes related to Guillain-Barre Syndrome:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.22 ALB CD40LG CD79A DAAM2 HCRT HLA-DQB1
2 cellular MP:0005384 10.2 CD79A HLA-DQB1 HP MBP MPZ PMP22
3 behavior/neurological MP:0005386 10.13 HCRT HLA-DQB1 MBP MPZ PMP2 PMP22
4 hematopoietic system MP:0005397 10.09 CD40LG CD79A HLA-DQB1 HP MBP MPZ
5 immune system MP:0005387 10.02 TNFRSF1A TNFRSF1B CD40LG CD79A HLA-DQB1 HP
6 liver/biliary system MP:0005370 9.87 ALB CD79A HLA-DQB1 HP TNF TNFRSF1A
7 muscle MP:0005369 9.8 TNFRSF1A TNFRSF1B ALB HCRT HLA-DQB1 PMP22
8 nervous system MP:0003631 9.7 CD40LG CD79A HCRT HLA-DQB1 MBP MPZ
9 neoplasm MP:0002006 9.63 TNF TNFRSF1A TNFRSF1B ALB CD79A HP
10 renal/urinary system MP:0005367 9.17 ALB CD40LG CD79A HLA-DQB1 HP TNFRSF1A

Drugs & Therapeutics for Guillain-Barre Syndrome

Drugs for Guillain-Barre Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 29)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Vaccines Phase 4,Phase 3,Phase 1
2 Antibodies Phase 3,Phase 2
3 Immunoglobulins Phase 3,Phase 2
4
4-Aminopyridine Approved Phase 2 504-24-5 1727
5
Prednisone Approved, Vet_approved Phase 2 53-03-2 5865
6 Complement System Proteins Phase 2
7 gamma-Globulins Phase 2
8 Immunoglobulins, Intravenous Phase 2
9 Pharmaceutical Solutions Phase 2
10 Rho(D) Immune Globulin Phase 2
11 Potassium Channel Blockers Phase 2
12 Anti-Inflammatory Agents Phase 2
13 Antineoplastic Agents, Hormonal Phase 2
14 glucocorticoids Phase 2
15 Hormone Antagonists Phase 2
16 Hormones Phase 2
17 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 2
18 Chorionic Gonadotropin Phase 2
19
nivolumab Approved 946414-94-4
20
Thiamine Approved, Investigational, Nutraceutical, Vet_approved 59-43-8 1130
21
Citric Acid Approved, Nutraceutical, Vet_approved 77-92-9 311
22 Vitamin B Complex
23 Vitamins
24 Anticoagulants
25 Calcium, Dietary
26 Chelating Agents
27 Autoantibodies
28 Thiamin Nutraceutical
29 Citrate Nutraceutical

Interventional clinical trials:

(show all 42)

# Name Status NCT ID Phase Drugs
1 Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of Age Completed NCT01985997 Phase 4
2 Efficacy and Safety Study of GB-0998 for Guillain-Barré Syndrome Completed NCT02342184 Phase 3 GB-0998
3 Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré Syndrome Completed NCT02221271 Phase 3 NPB-01
4 Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801 Completed NCT01604746 Phase 3
5 Study to Evaluate the Long-term Antibody Persistence of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine (GSK134612) Versus Mencevax ACWY in Healthy Adolescents and Adults and Booster Response to MenACWY-TT Vaccine Administered at 10 Years Post-prima Recruiting NCT01934140 Phase 3
6 A Study To Evaluate A Booster Dose Of Menacwy-tt Vaccine Administered 10 Years After Healthy Subjects Aged 11-17 Years Received Either Menacwy-tt Vaccine (Nimenrix(Registered)) Or Mencevax Acwy(Registered). Recruiting NCT03189745 Phase 3
7 Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine Administered 6 Years Post-MenC Primary Vaccination in Healthy Subjects Who Were 12-18 Months at Primary Vaccination Active, not recruiting NCT01777308 Phase 3
8 Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome Study Unknown status NCT02029378 Phase 2 Eculizumab
9 Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) Patients Completed NCT02780570 Phase 2
10 Early Mechanical Ventilation for Guillain Barré Syndrome Completed NCT00167622 Phase 2
11 Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridine Completed NCT00056810 Phase 2 4-aminopyridine (4-AP)
12 JET-GBS - Japanese Eculizumab Trial for GBS Completed NCT02493725 Phase 2 Eculizumab;Placebo
13 Prednisone Treatment for Vestibular Neuronitis Completed NCT00271791 Phase 2 Prednisone;Prednisone
14 Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Implantation Failure Recruiting NCT03174964 Phase 2 IVIg
15 Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Pregnancy Loss Recruiting NCT03174951 Phase 2 IVIg
16 Study of GLS-5700 in Dengue Virus Seropositive Adults Active, not recruiting NCT02887482 Phase 1
17 Study of GLS-5700 in Healthy Volunteers Active, not recruiting NCT02809443 Phase 1
18 sCD163 as a Potential Biomarker in Guillain- Barré Syndrome Unknown status NCT02582853
19 The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin Innervation Unknown status NCT00173199
20 Change of Nerve Conduction Properties in IVIg Dependent Neuropathies Unknown status NCT01655394
21 Detection of Peripheral Blood Biomarkers in Intermediate Phase Spinal Cord Injury: Correlation With Neurological and Functional Outcomes, and Comparison to Other Central and Peripheral Neurological Conditions. Unknown status NCT01516385
22 Thiamin (Vitamin B1) Levels in Eating Disorder Adolescent Patients Unknown status NCT02164487
23 Perception and Multisensory Integration in Neurological Patients Using fMRI Unknown status NCT01469858
24 Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS) Completed NCT01306578 IVIG
25 Safety Study of GBS Following Menactra Meningococcal Vaccination Completed NCT00575653
26 Effects of Robotic-assisted Gait Training In Non-Ambulatory Patients After Guillain-Barré Syndrome Completed NCT02883270
27 Prospective Study on Swallowing/Breathing Interactions in Severe Guillain Barre Syndrome. Completed NCT01024088
28 Brain Computer Interface for Communication in ICU: a Feasibility Study Completed NCT01005524
29 Regional Citrate Anticoagulation in Plasma Exchange Treatment Completed NCT01370200
30 Cervarix Long-term Safety Surveillance Completed NCT01498627
31 Surveillance for Adverse Events Following Pandemic H1N1 Immunization Completed NCT01289418
32 Surveillance for Adverse Events Following Influenza Immunization Completed NCT01318876
33 Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United Kingdom Completed NCT01953822
34 Recovery of Visual Acuity in People With Vestibular Deficits Completed NCT00411216
35 International Guillain-Barré Syndrome Outcome Study Recruiting NCT01582763
36 Neurologic Manifestations of the Arbovirus Infection in Colombia Recruiting NCT03206541
37 Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology Practice Recruiting NCT02847728
38 Comparative Autoantibody and Immunologic Cell Marker Study Enrolling by invitation NCT02422875
39 Feasibility of Two New Software Modules for the Rehabilitation of Patients With Neuromuscular Upper Limb Impairments Not yet recruiting NCT03268304
40 Processing Integration in Neurological Patients Using fMRI Not yet recruiting NCT02722070
41 Randomized Study of Plasmapheresis or Human Immunoglobulin Infusion in Childhood Guillain-Barre Syndrome Terminated NCT00004833 Immune globulin
42 Gastrointestinal Transit Time in Patients With Guillain-Barré Syndrome Withdrawn NCT02459808

Search NIH Clinical Center for Guillain-Barre Syndrome

Inferred drug relations via UMLS 69 / NDF-RT 47 :


Cochrane evidence based reviews: guillain-barre syndrome

Genetic Tests for Guillain-Barre Syndrome

Anatomical Context for Guillain-Barre Syndrome

MalaCards organs/tissues related to Guillain-Barre Syndrome:

38
Testes, Brain, Spinal Cord, Heart, Eye, Skin, T Cells

Publications for Guillain-Barre Syndrome

Articles related to Guillain-Barre Syndrome:

(show top 50) (show all 190)
# Title Authors Year
1
Case report: Guillain-Barre syndrome with pneumococcus - A new association in pediatrics. ( 29387550 )
2018
2
Characteristics, incidence and outcome of patients admitted to intensive care unit with Guillain-Barre syndrome in Australia and New Zealand. ( 29413724 )
2018
3
Acute-onset Restless legs syndrome in acute neurological conditions-a prospective study on patients with the Guillain-Barre syndrome and acute stroke. ( 29359321 )
2018
4
Guillain-Barre syndrome caused by hepatitis E infection: case report and literature review. ( 29357816 )
2018
5
Disturbance of Plasma Lipid Metabolic Profile in Guillain-Barre Syndrome. ( 28811529 )
2017
6
Bilateral Ptosis due to Sympathetic Dysfunction as a Feature of Guillain-Barre Syndrome. ( 28827488 )
2017
7
Clinical association: Lyme disease and Guillain-Barre syndrome. ( 28711274 )
2017
8
Guillain Barre Syndrome in the elderly: Experience from a tertiary-care hospital in India. ( 28890042 )
2017
9
Guillain-Barre Syndrome with Falciparum Malaria and Scrub Typhus Mixed Infection-An Unusual Combination. ( 29207762 )
2017
10
Value of protein concentration in cerebrospinal fluid in paediatric patients with Guillain-Barre syndrome. ( 28870420 )
2017
11
Early electrophysiological findings in acute inflammatory demyelinating polyradiculoneuropathy variant of Guillain-Barre syndrome in the Pakistani populationA -A a comparison with global data. ( 29091318 )
2017
12
Long-term complete remission in a patient with focal segmental glomerulosclerosis associated with Guillain-Barre syndrome. ( 28921751 )
2017
13
Ventilator-Associated Pneumonia (VAP) in a Patient with Guillain-Barre Syndrome. ( 28790230 )
2017
14
Zika virus-induced neurological critical illness in Latin America: Severe Guillain-Barre Syndrome and encephalitis. ( 28806562 )
2017
15
Guillain-Barre Syndrome Induced by Heat Stroke: a Case Report and Literature Review. ( 28879705 )
2017
16
Familial amyloid cardiomyopathy masquerading as chronic Guillain-Barre syndrome: things are not always what they seem. ( 28425041 )
2017
17
Acute Fulminant Uremic Neuropathy Following Coronary Angiography Mimicking Guillain-Barre Syndrome. ( 28706599 )
2017
18
Reversible Splenial Lesion Syndrome After Intravenous Immunoglobulin Treatment for Guillain-Barre Syndrome. ( 28816832 )
2017
19
Reducing the economic burden in management of Guillain-Barre syndrome using modified plasmapheresis. ( 27605847 )
2016
20
Guillaine-barre syndrome; a rare complication of melioidosis. a case report. ( 27506202 )
2016
21
Carcinoid Tumor-Associated Paraneoplastic Polyneuropathy that Mimics Guillain-Barre Syndrome. ( 28360817 )
2016
22
Concurrency of Guillain-Barre syndrome and acute transverse myelitis: a case report and review of literature. ( 28018472 )
2016
23
Concomitant Guillain Barre Syndrome and Transverse Myelitis as Initial Neuropsychiatric Manifestation in a Case of Lupus: A Diagnostic Quandary. ( 27242943 )
2016
24
Poster 353 Acute Onset Chronic Inflammatory Demyelinating Polyneuropathy (A-CIDP) with CNS Involvement Initially Diagnosed as Guillain-Barre Syndrome (GBS): A Case Report. ( 27673107 )
2016
25
Author response: Successful treatment of Guillain-Barre syndrome by Ayurvedic treatment. ( 27621525 )
2016
26
Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome. ( 26293489 )
2016
27
Bilateral Ptosis as the First Presentation of Guillain-Barre Syndrome. ( 27057192 )
2016
28
Facial Diplegia with Paresthesia: An Uncommon Variant of Guillain-Barre Syndrome. ( 27630886 )
2016
29
The pathogenesis of demyelinating form of Guillain-Barre syndrome: proteo-peptidomic and immunological profiling of physiological fluids. ( 27143409 )
2016
30
Vision Loss in Guillain-Barre Syndrome: Is it a Complication of Guillain-Barre Syndrome or Just a Coincidence? ( 27621799 )
2016
31
Electrophysiological observations in critically ill Guillain-Barre syndrome. ( 27625229 )
2016
32
Poster 344 Upper Extremity Weakness Due to Bilateral Brachial Plexopathy from Guillain-Barre Syndrome in a Cancer Patient: A Case Report. ( 27673098 )
2016
33
Successful treatment of Guillain-Barre syndrome by Ayurvedic treatment. ( 27143805 )
2016
34
An Overlapping Case of Miller Fisher Syndrome, Bickerstaff's Encephalitis, and the ASMAN Variant of Guillain-Barre Syndrome. ( 27974981 )
2016
35
Prevalence of Autonomic Dysfunction in Hospitalized Patients with Guillain- Barre Syndrome. ( 28039863 )
2016
36
Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis and Guillain-Barre Syndrome in a 16-Month-Old Child. ( 28503601 )
2016
37
Guillain-Barre syndrome in acute lymphoblastic leukemia: Causal or coincidental. ( 25878750 )
2015
38
Acute toxic neuropathy mimicking guillain barre syndrome. ( 25811007 )
2015
39
Similarities of serum anti-ganglioside antibodies in first and third episodes of recurrent Guillain-Barre syndrome: case report. ( 25845761 )
2015
40
Guillain-Barre Syndrome: Clinical Presentation, Treatment Pattern And Outcome. ( 26533694 )
2015
41
Outcome of Guillain-Barre syndrome patients with respiratory paralysis. ( 26475599 )
2015
42
A Case of Visceral Autonomic Neuropathy Complicated by Guillain-Barre Syndrome Accompanied with Cyclic Vomiting Syndrome-like Disorder in a Child. ( 26157699 )
2015
43
Guillain - Barre syndrome in a patient with acute myocardial infarction with ventricular septal defect repair treated with plasma exchange. ( 25722582 )
2015
44
Acute hemiplegia as a rare presentation of infantile Guillain-Barre syndrome. ( 25399226 )
2014
45
Reversible cardiomyopathy in Guillain Barre syndrome. ( 25856949 )
2014
46
Acute Motor-Sensory Axonal Neuropathy With Hyperreflexia in Guillain-Barre Syndrome. ( 24700665 )
2014
47
Cardiac arrest after succinylcholine administration in a patient recovering from guillain-barre syndrome. ( 25327929 )
2014
48
Guillain-Barre Syndrome, Influenza and Influenza Vaccination--the Epidemiologic Evidence. ( 24415636 )
2014
49
Association between human leukocyte antigen-DR and demylinating Guillain-Barre syndrome. ( 25274590 )
2014
50
A rare neurological complication of typhoid fever: Guillain-Barre' syndrome. ( 25250072 )
2014

Variations for Guillain-Barre Syndrome

Expression for Guillain-Barre Syndrome

Search GEO for disease gene expression data for Guillain-Barre Syndrome.

Pathways for Guillain-Barre Syndrome

Pathways related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

(show all 19)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.48 CD40LG TNF TNFRSF1A TNFRSF1B
2 12.28 CD40LG CD79A TNF TNFRSF1A TNFRSF1B
3
Show member pathways
12.07 CD40LG HLA-DQB1 TNF TNFRSF1A
4 12.05 CD40LG TNF TNFRSF1A TNFRSF1B
5
Show member pathways
11.81 TNF TNFRSF1A TNFRSF1B
6 11.78 TNF TNFRSF1A TNFRSF1B
7 11.74 MBP MPZ PMP22
8 11.7 CD40LG TNF TNFRSF1A
9
Show member pathways
11.66 CD40LG CD79A HLA-DQB1 TNF TNFRSF1A TNFRSF1B
10 11.55 TNF TNFRSF1A TNFRSF1B
11
Show member pathways
11.5 CD40LG TNF TNFRSF1A
12 11.42 TNF TNFRSF1A TNFRSF1B
13
Show member pathways
11.37 CD40LG TNF TNFRSF1A TNFRSF1B
14
Show member pathways
11.33 TNF TNFRSF1A TNFRSF1B
15 11.3 TNF TNFRSF1A TNFRSF1B
16
Show member pathways
11.14 TNF TNFRSF1A TNFRSF1B
17
Show member pathways
11.12 CD40LG TNF TNFRSF1A TNFRSF1B
18 11.02 CD40LG TNFRSF1A TNFRSF1B
19 10.94 TNF TNFRSF1A TNFRSF1B

GO Terms for Guillain-Barre Syndrome

Cellular components related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 membrane raft GO:0045121 9.46 CD79A TNF TNFRSF1A TNFRSF1B
2 compact myelin GO:0043218 8.96 MBP PMP22
3 myelin sheath GO:0043209 8.92 ALB MBP MPZ PMP2

Biological processes related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.73 HCRT MBP MPZ PMP22
2 positive regulation of membrane protein ectodomain proteolysis GO:0051044 9.48 TNF TNFRSF1B
3 positive regulation of ceramide biosynthetic process GO:2000304 9.46 TNF TNFRSF1A
4 intrinsic apoptotic signaling pathway in response to DNA damage GO:0008630 9.43 TNF TNFRSF1A TNFRSF1B
5 death-inducing signaling complex assembly GO:0071550 9.4 TNF TNFRSF1A
6 regulation of establishment of endothelial barrier GO:1903140 9.37 TNF TNFRSF1A
7 myelination GO:0042552 9.33 MBP MPZ PMP22
8 regulation of immunoglobulin secretion GO:0051023 9.32 CD40LG TNF
9 tumor necrosis factor-mediated signaling pathway GO:0033209 9.26 CD40LG TNF TNFRSF1A TNFRSF1B
10 immune response GO:0006955 9.1 CD40LG HLA-DQB1 MBP TNF TNFRSF1A TNFRSF1B

Molecular functions related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 fatty acid binding GO:0005504 8.62 ALB PMP2

Sources for Guillain-Barre Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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