GBS
MCID: GLL022
MIFTS: 56

Guillain-Barre Syndrome (GBS) malady

Categories: Rare diseases, Neuronal diseases, Immune diseases

Aliases & Classifications for Guillain-Barre Syndrome

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Aliases & Descriptions for Guillain-Barre Syndrome:

Name: Guillain-Barre Syndrome 11 48 25 50 38 39 13 68
Gbs 48 25 2
Acute Inflammatory Demyelinating Polyneuropathy 48 68
Acute Inflammatory Polyneuropathy 48 25
Guillain-Barré Syndrome 48 25
Fisher Syndrome 25 49
Acute Inflammatory Demyelinating Polyradiculoneuropathy 48
Acute Autoimmune Peripheral Neuropathy 48
Landry-Guillain-Barre-Strohl Syndrome 48
Acute Immune-Mediated Polyneuropathy 48
Acute Postinfectious Polyneuropathy 11
 
Guillain-Barré-Strohl Syndrome 48
Landry-Guillain-Barre Syndrome 25
Acute Inflammatory Neuropathy 48
Acute Infectious Polyneuritis 25
Post-Infectious Polyneuritis 11
Landry's Ascending Paralysis 48
Acute Infective Polyneuritis 11
Post-Infective Polyneuritis 48
Postinfectious Polyneuritis 11
Miller Fisher Syndrome 68
Infectious Neuronitis 11

Classifications:



External Ids:

Disease Ontology11 DOID:12842
ICD1030 G61.0
MeSH39 D020275
NCIt45 C116345

Summaries for Guillain-Barre Syndrome

About this section
MedlinePlus:38 Guillain-barre syndrome is a rare disorder that causes your immune system to attack your peripheral nervous system (pns). the pns nerves connect your brain and spinal cord with the rest of your body. damage to these nerves makes it hard for them to transmit signals. as a result, your muscles have trouble responding to your brain. no one knows what causes the syndrome. sometimes it is triggered by an infection, surgery, or a vaccination. the first symptom is usually weakness or a tingling feeling in your legs. the feeling can spread to your upper body. in severe cases, you become almost paralyzed. this is life-threatening. you might need a respirator to breathe. symptoms usually worsen over a period of weeks and then stabilize. guillain-barre can be hard to diagnose. possible tests include nerve tests and a spinal tap. most people recover. recovery can take a few weeks to a few years. treatment can help symptoms, and may include medicines or a procedure called plasma exchange. nih: national institute of neurological disorders and stroke

MalaCards based summary: Guillain-Barre Syndrome, also known as GBS, is related to rabies and tularemia, and has symptoms including back pain, headache and neuralgia. An important gene associated with Guillain-Barre Syndrome is MBP (Myelin Basic Protein), and among its related pathways are Neural Crest Differentiation and Cellular Transformation by HTLV1. The drug immunoglobulins, intravenous has been mentioned in the context of this disorder. Affiliated tissues include testes, heart and spinal cord, and related mouse phenotypes are Decreased viability and neoplasm.

NIH Rare Diseases:48 Guillain-barré syndrome (gbs) is a rare disorder in which the body's immune system attacks part of the peripheral nervous system. symptoms include muscle weakness, numbness, and tingling sensations, which can increase in intensity until the muscles cannot be used at all. usually gbs occurs a few days or weeks after symptoms of a viral infection. it remains unclear why only some people develop gbs but there may be a genetic predisposition in some cases. diagnosed patients should be admitted to a hospital for early treatment. there is no cure for gbs, but treatments such as plasma exchange (plasmapheresis) and high dose immunoglobulins may reduce how severe the symptoms are and how long the symptoms last. recovery can take as little as a few days to as long as a few years. about 30% of those with gbs have permanent weakness. a small number may suffer a relapse many years after the initial attack. last updated: 5/12/2017

CDC:2 Group B Streptococcus (group B strep) is a type of bacteria that causes illness in people of all ages. Also known as GBS, group B strep disease is the most common cause of severe infections in newborns that can be deadly, but it can be prevented.

NINDS:49 Miller Fisher syndrome is a rare, acquired nerve disease that is considered to be a variant of Guillain-Barré syndrome. It is characterized by abnormal muscle coordination, paralysis of the eye muscles, and absence of the tendon reflexes. Like Guillain-Barré syndrome, symptoms may be preceded by a viral illness. Additional symptoms include generalized muscle weakness and respiratory failure. The majority of individuals with Miller Fisher syndrome have a unique antibody that characterizes the disorder.

Disease Ontology:11 An autoimmune disease of peripheral nervous system that causes body's immune system to attack part of the peripheral nervous system.

Wikipedia:71 Guillain–Barré syndrome (GBS) is a rapid-onset muscle weakness caused by the immune system... more...

Related Diseases for Guillain-Barre Syndrome

About this section

Diseases related to Guillain-Barre Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 269)
idRelated DiseaseScoreTop Affiliating Genes
1rabies29.8CD40LG, CD79A
2tularemia29.7CD40LG, CD79A, TNF
3celiac disease29.3CD40LG, CD79A, TNF, TNFRSF1A, TNFRSF1B
4pharyngeal-cervical-brachial variant of guillain-barré syndrome12.2
5paraparetic variant of guillain-barré syndrome12.1
6miller fisher syndrome11.9
7neuropathy, inflammatory demyelinating11.8
8chronic inflammatory demyelinating polyneuropathy11.6
9autonomic dysfunction11.4
10dysautonomia11.4
11dysautonomia, familial11.1
12peripheral nervous system disease11.1
13acute flaccid myelitis11.1
14zika virus infection11.1
15hereditary type 2 neuropathy10.4MPZ, PMP22
16congenital dyserythropoietic anemia10.3ALB, TNF
17chrna1-related congenital myasthenic syndrome10.3MPZ, PMP22
18surfactant metabolism dysfunction, pulmonary, 210.3MPZ, PMP22
19hypertonia10.3MPZ, PMP22
20atopic dermatitis 610.3ALB, CD79A
21schneiderian carcinoma10.3ALB, CD79A
22craniorachischisis10.3MBP, MPZ, PMP22
23influenza10.3
24charcot-marie-tooth disease, type 1e10.3MBP, MPZ, PMP22
25occupational dermatitis10.3TNF, TNFRSF1B
26mohr-tranebjaerg syndrome10.3MBP, MPZ, PMP22
27childhood infratentorial neoplasm10.3PMP22, TNF, TNFRSF1B
28korsakoff's amnesic syndrome10.3MBP, MPZ, PMP22
29cardiac sarcoidosis10.2TNF, TNFRSF1B
30mikulicz disease10.2ALB, CD79A, TNF
31bladder sarcoma10.2ALB, CD79A, TNF
32autosomal recessive pericentral pigmentary retinopathy10.2TNF, TNFRSF1A
33paranasal sinus sarcoma10.2ALB, CD79A, TNF
34familial nephrotic syndrome10.2ALB, CD79A, TNF
35candidiasis, familial, 4, autosomal recessive10.2TNF, TNFRSF1A
36imaizumi kuroki syndrome10.2HCRT, HLA-DQB1
37biliary cirrhosis, primary, 210.2ALB, CD79A, TNF
38aortic valve prolapse10.2ALB, HP, PMP22
39nephrosclerosis10.2CD79A, HLA-DQB1, TNFRSF1B
40multiple epiphyseal dysplasia10.2TNF, TNFRSF1A, TNFRSF1B
41brain compression10.2PMP22, TNFRSF1A, TNFRSF1B
42von economo's disease10.2ALB, MBP, MPZ, PMP22
43primary ciliary dyskinesia10.2TNF, TNFRSF1A, TNFRSF1B
44migraine with aura10.2HLA-DQB1, HP, TNF
45apple allergy10.2HLA-DQB1, HLA-DRB1
46pigmentation disease10.2ALB, HP, TNF
47hemoglobin d disease10.2HLA-DQB1, HLA-DRB1
48neuropathy10.1
49hodgkin's paragranuloma10.1HCRT, HLA-DQB1
50bilateral parasagittal parieto-occipital polymicrogyria10.1HLA-DQB1, HLA-DRB1, TNF

Graphical network of the top 20 diseases related to Guillain-Barre Syndrome:



Diseases related to guillain-barre syndrome

Symptoms & Phenotypes for Guillain-Barre Syndrome

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UMLS symptoms related to Guillain-Barre Syndrome:


back pain, headache, neuralgia, pain, sciatica, seizures, syncope, tremor, chronic pain, vertigo/dizziness, sleeplessness, cerebellar ataxia, ophthalmoplegia

GenomeRNAi Phenotypes related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

26
idDescriptionGenomeRNAi Source AccessionScoreTop Affiliating Genes
1GR00381-A-110.3CD79A, HLA-DQB1, MPZ

MGI Mouse Phenotypes related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.9ALB, CD79A, HP, TNF, TNFRSF1A, TNFRSF1B
2MP:00053708.5ALB, CD79A, HLA-DQB1, HP, TNF, TNFRSF1A
3MP:00053698.2ALB, HCRT, HLA-DQB1, PMP22, TNF, TNFRSF1A
4MP:00053978.0CD40LG, CD79A, HLA-DQB1, HP, MBP, MPZ
5MP:00053878.0CD40LG, CD79A, HLA-DQB1, HP, MBP, MPZ
6MP:00053867.8HCRT, HLA-DQB1, MBP, MPZ, PMP2, PMP22
7MP:00053677.6ALB, CD40LG, CD79A, HLA-DQB1, HP, TNFRSF1A
8MP:00053847.5ALB, CD40LG, CD79A, HLA-DQB1, HP, MBP
9MP:00036317.0CD40LG, CD79A, HCRT, HLA-DQB1, MBP, MPZ
10MP:00053766.5ALB, CD40LG, CD79A, HCRT, HLA-DQB1, HP

Drugs & Therapeutics for Guillain-Barre Syndrome

About this section

Drugs for Guillain-Barre Syndrome (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1VaccinesPhase 4, Phase 3, Phase 16611
2ImmunoglobulinsPhase 3, Phase 26394
3AntibodiesPhase 3, Phase 26394
4
4-AminopyridineapprovedPhase 269504-24-51727
Synonyms:
.gamma.-Aminopyridine
275875_ALDRICH
36687_FLUKA
36687_RIEDEL
4 AP
4 Aminopyridine
4 Aminopyridine Sustained Release
4-AP
4-Aminopyridine
4-Aminopyridine 10
4-Aminopyridine Sustained Release
4-Pyridinamine
4-Pyridylamine
4-aminopyridine
5-22-09-00106 (Beilstein Handbook Reference)
504-24-5
A 0152
A0414
A78403_ALDRICH
AB1004971
AC-907/25014071
AC1L1C3R
AC1Q52BM
AI3-52547
AKOS000119896
Amaya
Amino-4 pyridine
Amino-4-Pyridine
Ampydin
Ampyra
Avitrol
Avitrol 200
BB_SC-6974
BRN 0105782
BSPBio_001562
Bio1_000353
Bio1_000842
Bio1_001331
Bio2_000282
Bio2_000762
C13728
C5H6N2
CHEBI:34385
CHEMBL284348
CID1727
Caswell No. 038
Compound 1861
D015761
D04127
Dalfampridine
DivK1c_000572
EINECS 207-987-9
EL-970
EPA Pesticide Chemical Code 069201
EU-0100032
FT-0083754
Fampridina
Fampridine
Fampridine (USAN/INN)
Fampridine SR
Fampridine [USAN:INN]
Fampridine-PR
Fampridine-SR
Fampridinum
HC150041
HMS1361O04
HMS1791O04
HMS1921H15
HMS1989O04
HMS2092F05
HMS501M14
HSDB 6037
IDI1_000572
IDI1_034032
InChI=1/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7
KBio1_000572
 
KBio2_000282
KBio2_000635
KBio2_002850
KBio2_003203
KBio2_005418
KBio2_005771
KBio3_000563
KBio3_000564
KBio3_001888
KBioGR_000282
KBioGR_001505
KBioSS_000282
KBioSS_000635
LS-130202
Lopac-A-0152
Lopac0_000032
MLS000069400
Mi-W-3
MolPort-000-146-022
N07XX07
NCGC00015009-01
NCGC00015009-03
NCGC00015009-12
NCGC00024890-01
NCGC00024890-02
NCGC00024890-03
NCGC00024890-04
NCGC00024890-05
NCGC00024890-06
NCGC00024890-07
NCGC00024890-08
NCGC00024890-09
NCGC00024890-10
NINDS_000572
NSC 15041
NSC15041
Neurelan
Neurelan (TN)
P-Aminopyridine
PYRIDINE,4-AMINO
Philips 1861
Phillips 1861
Pimadin (free base)
Prc 1237
Pymadin
Pymadine
RCRA waste no. P008
SDCCGMLS-0066228.P001
SMR000058211
SPBio_001486
SPECTRUM1501130
STK298717
Spectrum2_001413
Spectrum3_000914
Spectrum4_001013
Spectrum5_001501
Spectrum_000155
Sustained Release, 4-Aminopyridine
TL8003344
Tocris-0940
UNII-BH3B64OKL9
UPCMLD-DP125
UPCMLD-DP125:001
VMI 10-3
VMI 103
VMI-10-3
VMI-103
VMI103
WLN: T6NJ DZ
[J.Pharmacol.Exp.Ther. 275:864 (1995)]
gamma-Aminopyridine
nchem.892-comp4
p-Aminopyridine
p-Aminopyridine [UN2671] [Poison]
p-Aminopyridine [UN2671] [Poison]
pyridin-4-amine
pyridin-4-ylamine
5Complement System ProteinsPhase 2232
6Immunoglobulins, IntravenousPhase 2333
7Rho(D) Immune GlobulinPhase 2326
8Potassium Channel BlockersPhase 2180
9gamma-GlobulinsPhase 2326
10Pharmaceutical SolutionsPhase 28192
11
nivolumabapproved424946414-94-4
Synonyms:
BMS-936558
 
MDX-1106
ONO-4538
nivolumab
12
Thiamineapproved, nutraceutical, vet_approved10159-43-81130
Synonyms:
100660-17-1
115461-66-0
1sbr
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol
2-[3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-3-ium-5-yl]ethanol chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydrox yethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethylthiazolium chloride, monohydrochloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methylthiazolium chloride monohydrochloride
3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM
3-(4-AMINO-2-methyl-pyrimidin-5-ylmethyl)-5-(2-hydroxy-ethyl)-4-methyl-thiazol-3-ium
3-[(4-amino-2-methyl-5-pyrimidinyl)methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride
3-[(4-amino-2-methylpyrimidin-5-yl)methyl]-5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium chloride hydrochloride
3[(4-Amino-2-methyl-5-pyrimidinyl)-methyl]-5-(2-hydroxyethyl)-4-methylthiazolium chloride
55463-15-5
57777-32-9
59-43-8
67-03-8
AC-11683
AC1L1ASK
AC1L1LOC
AC1LAODT
AC1Q4V9Q
AI3-18993
AKOS000668650
AR-1L8201
Aneurin
Aneurine
Antiberiberi factor
Apatate drape
Apate drops
B-Amin
BAS 00266240
BPBio1_000686
BSPBio_000622
Beatine
Bedome
Begiolan
Beivon
Benerva
Bequin
Berin
Betabion
Betalin S
Betaxin
Bethiamin
Bethiazine
Beuion
Bevitex
Bevitine
Bewon
Biamine
Bithiamin
Biuno
Bivatin
Bivita
C00378
C12H17N4OS
CCRIS 1906
CCRIS 5823
CHEBI:18385
CHEBI:33283
CHEBI:49105
CHEMBL1547
CHEMBL1588
CID1130
CID517305
CID6042
Cernevit-12
Chloride-hydrochloride salt of thiamine
Clotiamina
D08580
DB00152
EINECS 200-425-3
EINECS 200-641-8
Eskapen
Eskaphen
FEMA No. 3322
 
HSDB 220
Hybee
I14-14339
LS-3226
LT00233141
Lixa-beta
MLS001304099
Metabolin
MolPort-000-722-048
MolPort-001-920-086
MolPort-002-052-059
NChemBio.2007.13-comp10
NSC 36226
NSC36226
Oryzanin
Oryzanine
Prestwick0_000631
Prestwick1_000631
Prestwick2_000631
Prestwick3_000631
SBB058094
SMP1_000084
SMR000718788
SPBio_002841
ST095175
Slowten
THD
THIAMIN, VITAMIN B1
Thiadoxine
Thiamin
Thiamin dichloride
Thiaminal
Thiamine
Thiamine (INN)
Thiamine HCL
Thiamine [INN:BAN]
Thiamine chloride
Thiamine chloride hydrochloride
Thiamine dichloride
Thiamine hydrochloride [JAN]
Thiamine monochloride
Thiamine monohydrochloride
Thiamine, chloride
Thiamine, chloride, hydrochloride
Thiamine, monohydrochloride
Thiaminium
Thiaminium chloride hydrochloride
Thiaminum
Thiaminum [INN-Latin]
Thiamol
Thiavit
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-m- ethyl, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl- chloride (1:1)
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-, chloride, monohydrochloride
Thiazolium, 3-((4-amino-2-methyl-5-pyrimidinyl)methyl)-5-(2-hydroxyethyl)-4-methyl-chloride
Tiamidon
Tiamina
Tiamina [INN-Spanish]
Tiaminal
TimTec1_000613
Trophite
UNII-X66NSO3N35
VIB
Vetalin S
Vinothiam
Vitamin B1
Vitamin B1 (TN)
Vitamin B1 hydrochloride (VAN)
Vitaneurin
Vitaneuron
ZINC00049153
[5-[[5-(2-hydroxyethyl)-4-methyl-1,3-thiazol-3-ium-3-yl]methyl]-2-methylpyrimidin-4-yl]azanium dichloride
bmse000274
nchembio.121-comp5
thiamin
thiamine
thiamine(1+)
thiamine(1+) ion
thiaminium
vitamin B1
vitamin b1(thiamine)
13Vitamins5282
14Vitamin B Complex4337
15Anticoagulants2623
16Chelating Agents1423
17Calcium, Dietary5713
18Autoantibodies130
19Immunoglobulin G275
20ThiaminNutraceutical101
21CitrateNutraceutical1160
22
Citric Acidnutraceutical, vet_approved116077-92-9311
Synonyms:
2-Hydroxy-1,2,3-propanetricarboxylate
2-Hydroxy-1,2,3-propanetricarboxylic acid
2-Hydroxytricarballylic acid
3-Carboxy-3-hydroxypentane-1,5-dioate
3-Carboxy-3-hydroxypentane-1,5-dioic acid
Aciletten
Anhydrous citrate
Anhydrous citric acid
Chemfill
Citraclean
 
Citrate
Citretten
Citric acid
Citro
Citronensäure
E 330
Hydrocerol A
Kyselina citronova
Suby G
Uro-trainer
beta-Hydroxytricarballylate
beta-Hydroxytricarballylic acid

Interventional clinical trials:

(show all 38)
idNameStatusNCT IDPhase
1Postmarketing Safety Study of Q/LAIV in Subjects 2 Through 49 Years of AgeCompletedNCT01985997Phase 4
2Efficacy and Safety Study of GB-0998 for Guillain-Barré SyndromeCompletedNCT02342184Phase 3
3Phase III Clinical Trial of NPB-01 in Patients With Guillain-Barré SyndromeCompletedNCT02221271Phase 3
4Additional 6-Month Safety Follow-up After Completion of Precursor Study 880801CompletedNCT01604746Phase 3
5Study to Evaluate the Long-term Antibody Persistence of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine (GSK134612) Versus Mencevax ACWY in Healthy Adolescents and Adults and Booster Response to MenACWY-TT Vaccine Administered at 10 Years Post-primaActive, not recruitingNCT01934140Phase 3
6Immunogenicity, Reactogenicity and Safety of GlaxoSmithKline (GSK) Biologicals' MenACWY-TT Vaccine Administered 6 Years Post-MenC Primary Vaccination in Healthy Subjects Who Were 12-18 Months at Primary VaccinationActive, not recruitingNCT01777308Phase 3
7Inhibition of Complement Activation (Eculizumab) in Guillain-Barre Syndrome StudyUnknown statusNCT02029378Phase 2
8Early Mechanical Ventilation for Guillain Barré SyndromeCompletedNCT00167622Phase 2
9Assessment of Chronic Guillain-Barre Syndrome Improvement With Use of 4-aminopyridineCompletedNCT00056810Phase 2
10JET-GBS - Japanese Eculizumab Trial for GBSCompletedNCT02493725Phase 2
11Small Volume Plasma Exchange (SVPE) for Guillain-Barré Syndrome (GBS) PatientsRecruitingNCT02780570Phase 2
12Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Implantation FailureRecruitingNCT03174964Phase 2
13Immunomodulatory Effects of IVIg on Pregnancy Rate of Patient With Recurrent Pregnancy LossRecruitingNCT03174951Phase 2
14Study of GLS-5700 in Dengue Virus Seropositive AdultsRecruitingNCT02887482Phase 1
15Study of GLS-5700 in Healthy VolunteersActive, not recruitingNCT02809443Phase 1
16The Changes of Cytokines in Guillain Barré Syndrome: the Correlation With Clinical Manifestations and Skin InnervationUnknown statusNCT00173199
17Change of Nerve Conduction Properties in IVIg Dependent NeuropathiesUnknown statusNCT01655394
18Detection of Peripheral Blood Biomarkers in Intermediate Phase Spinal Cord Injury: Correlation With Neurological and Functional Outcomes, and Comparison to Other Central and Peripheral Neurological Conditions.Unknown statusNCT01516385
19Thiamin (Vitamin B1) Levels in Eating Disorder Adolescent PatientsUnknown statusNCT02164487
20Perception and Multisensory Integration in Neurological Patients Using fMRIUnknown statusNCT01469858
21Intravenous Immunoglobulin (IVIG) Versus Plasma Exchange (PE) for Ventilated Children With Guillain Barre Syndrome (GBS)CompletedNCT01306578
22Safety Study of GBS Following Menactra Meningococcal VaccinationCompletedNCT00575653
23Effects of Robotic-assisted Gait Training In Non-Ambulatory Patients After Guillain-Barré SyndromeCompletedNCT02883270
24Prospective Study on Swallowing/Breathing Interactions in Severe Guillain Barre Syndrome.CompletedNCT01024088
25Brain Computer Interface for Communication in ICU: a Feasibility StudyCompletedNCT01005524
26Regional Citrate Anticoagulation in Plasma Exchange TreatmentCompletedNCT01370200
27Cervarix Long-term Safety SurveillanceCompletedNCT01498627
28Surveillance for Adverse Events Following Pandemic H1N1 ImmunizationCompletedNCT01289418
29Surveillance for Adverse Events Following Influenza ImmunizationCompletedNCT01318876
30Clinical Trial to Evaluate Magtein in Older AdultsCompletedNCT02363634
31Study Assessing Risk of Autoimmune Diseases in Females (9 - 25 Years) Exposed to Cervarix® in United KingdomCompletedNCT01953822
32International Guillain-Barré Syndrome Outcome StudyRecruitingNCT01582763
33sCD163 as a Potential Biomarker in Guillain- Barré SyndromeRecruitingNCT02582853
34Pattern of Use and Safety/Effectiveness of Nivolumab in Routine Oncology PracticeRecruitingNCT02847728
35Comparative Autoantibody and Immunologic Cell Marker StudyEnrolling by invitationNCT02422875
36Processing Integration in Neurological Patients Using fMRINot yet recruitingNCT02722070
37Gastrointestinal Transit Time in Patients With Guillain-Barré SyndromeSuspendedNCT02459808
38Randomized Study of Plasmapheresis or Human Immunoglobulin Infusion in Childhood Guillain-Barre SyndromeTerminatedNCT00004833

Search NIH Clinical Center for Guillain-Barre Syndrome

Inferred drug relations via UMLS68/NDF-RT46:


Cochrane evidence based reviews: guillain-barre syndrome

Genetic Tests for Guillain-Barre Syndrome

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Anatomical Context for Guillain-Barre Syndrome

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MalaCards organs/tissues related to Guillain-Barre Syndrome:

36
Testes, Heart, Spinal cord, Eye, Brain, T cells

Publications for Guillain-Barre Syndrome

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Articles related to Guillain-Barre Syndrome:

(show top 50)    (show all 171)
idTitleAuthorsYear
1
The pathogenesis of demyelinating form of Guillain-Barre syndrome: proteo-peptidomic and immunological profiling of physiological fluids. (27143409)
2016
2
Vision Loss in Guillain-Barre Syndrome: Is it a Complication of Guillain-Barre Syndrome or Just a Coincidence? (27621799)
2016
3
Poster 344 Upper Extremity Weakness Due to Bilateral Brachial Plexopathy from Guillain-Barre Syndrome in a Cancer Patient: A Case Report. (27673098)
2016
4
Facial Diplegia with Paresthesia: An Uncommon Variant of Guillain-Barre Syndrome. (27630886)
2016
5
Successful treatment of Guillain-Barre syndrome by Ayurvedic treatment. (27143805)
2016
6
Bilateral Ptosis as the First Presentation of Guillain-Barre Syndrome. (27057192)
2016
7
Concomitant Guillain Barre Syndrome and Transverse Myelitis as Initial Neuropsychiatric Manifestation in a Case of Lupus: A Diagnostic Quandary. (27242943)
2016
8
Correlation Between Daam2 Expression Changes and Demyelination in Guillain-Barre Syndrome. (26293489)
2016
9
Poster 353 Acute Onset Chronic Inflammatory Demyelinating Polyneuropathy (A-CIDP) with CNS Involvement Initially Diagnosed as Guillain-Barre Syndrome (GBS): A Case Report. (27673107)
2016
10
Prevalence of Autonomic Dysfunction in Hospitalized Patients with Guillain- Barre Syndrome. (28039863)
2016
11
Electrophysiological observations in critically ill Guillain-Barre syndrome. (27625229)
2016
12
Concurrency of Guillain-Barre syndrome and acute transverse myelitis: a case report and review of literature. (28018472)
2016
13
Guillaine-barre syndrome; a rare complication of melioidosis. a case report. (27506202)
2016
14
Epstein-Barr Virus-Associated Hemophagocytic Lymphohistiocytosis and Guillain-Barre Syndrome in a 16-Month-Old Child. (28503601)
2016
15
Author response: Successful treatment of Guillain-Barre syndrome by Ayurvedic treatment. (27621525)
2016
16
An Overlapping Case of Miller Fisher Syndrome, Bickerstaff's Encephalitis, and the ASMAN Variant of Guillain-Barre Syndrome. (27974981)
2016
17
Reducing the economic burden in management of Guillain-Barre syndrome using modified plasmapheresis. (27605847)
2016
18
Guillain - Barre syndrome in a patient with acute myocardial infarction with ventricular septal defect repair treated with plasma exchange. (25722582)
2015
19
A Case of Visceral Autonomic Neuropathy Complicated by Guillain-Barre Syndrome Accompanied with Cyclic Vomiting Syndrome-like Disorder in a Child. (26157699)
2015
20
Outcome of Guillain-Barre syndrome patients with respiratory paralysis. (26475599)
2015
21
Guillain-Barre Syndrome: Clinical Presentation, Treatment Pattern And Outcome. (26533694)
2015
22
Acute toxic neuropathy mimicking guillain barre syndrome. (25811007)
2015
23
Guillain-Barre syndrome in acute lymphoblastic leukemia: Causal or coincidental. (25878750)
2015
24
Similarities of serum anti-ganglioside antibodies in first and third episodes of recurrent Guillain-Barre syndrome: case report. (25845761)
2015
25
A rare neurological complication of typhoid fever: Guillain-Barre' syndrome. (25250072)
2014
26
Relapsing Guillain-Barre syndrome in pregnancy and postpartum. (25221412)
2014
27
Guillain-Barre syndrome associated with preceding hepatitis E virus infection. (24415572)
2014
28
Acute Motor-Sensory Axonal Neuropathy With Hyperreflexia in Guillain-Barre Syndrome. (24700665)
2014
29
Acute hemiplegia as a rare presentation of infantile Guillain-Barre syndrome. (25399226)
2014
30
Association between human leukocyte antigen-DR and demylinating Guillain-Barre syndrome. (25274590)
2014
31
Diagnosis of Guillain-Barre syndrome and validation of Brighton criteria. (24163275)
2014
32
Guillain-Barre Syndrome, Influenza and Influenza Vaccination--the Epidemiologic Evidence. (24415636)
2014
33
Demographics, clinical features, outcome and prognostic factors of Guillain-Barre syndrome in Thai children. (25391180)
2014
34
Cardiac arrest after succinylcholine administration in a patient recovering from guillain-barre syndrome. (25327929)
2014
35
Reversible cardiomyopathy in Guillain Barre syndrome. (25856949)
2014
36
Anesthesia for cesarean section in a patient with Guillain-Barre syndrome: case report. (23931254)
2013
37
Acute hepatitis E complicated by Guillain-Barre syndrome in Portugal, December 2012--a case report. (23987830)
2013
38
An unusual case of Guillain-Barre syndrome following toxic shock syndrome in a burned child. (24182693)
2013
39
Chart-confirmed guillain-barre syndrome after 2009 H1N1 influenza vaccination among the Medicare population, 2009-2010. (23652165)
2013
40
Guillain-Barre syndrome with acute lymphoblastic leukemia. (24036643)
2013
41
Guillain-Barre syndrome as a paraneoplastic manifestation of disseminated squamous cell carcinoma. (23729714)
2013
42
Simple bedside predictors of mechanical ventilation in patients with Guillain-Barre syndrome. (24378177)
2013
43
The role of cytomegalovirus, Haemophilus influenzae and Epstein Barr virus in Guillain Barre syndrome. (23852841)
2013
44
Guillain-Barre syndrome presenting with severe hydrocephalus in a child. (24082947)
2013
45
Pharyngeal-cervical-brachial variant of Guillain-Barre syndrome. (23804237)
2013
46
Prevalence and profile of sleep disturbances in Guillain-Barre Syndrome: a prospective questionnaire-based study during 10 days of hospitalization. (22642612)
2013
47
Clinically silent posterior reversible encephalopathy in Guillain-Barre syndrome. (23573560)
2013
48
Guillain-Barre syndrome in an adult patient with Henoch-Schonlein purpura. (23559644)
2013
49
Epidemiological aspects of Guillain-Barre syndrome. (23821025)
2013
50
Guillain Barre syndrome as a manifestation of neurological melioidosis. (24339608)
2013

Variations for Guillain-Barre Syndrome

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Expression for genes affiliated with Guillain-Barre Syndrome

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Search GEO for disease gene expression data for Guillain-Barre Syndrome.

Pathways for genes affiliated with Guillain-Barre Syndrome

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Pathways related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

(show all 23)
idSuper pathwaysScoreTop Affiliating Genes
19.8MBP, MPZ, PMP22
2
Show member pathways
9.3TNF, TNFRSF1A, TNFRSF1B
3
Show member pathways
9.3TNF, TNFRSF1A, TNFRSF1B
49.3TNF, TNFRSF1A, TNFRSF1B
59.3TNF, TNFRSF1A, TNFRSF1B
69.3TNF, TNFRSF1A, TNFRSF1B
7
Show member pathways
9.3TNF, TNFRSF1A, TNFRSF1B
89.3TNF, TNFRSF1A, TNFRSF1B
99.3TNF, TNFRSF1A, TNFRSF1B
109.2HLA-DQB1, HLA-DRB1, TNF
119.2HLA-DQB1, HLA-DRB1, TNF
129.2CD40LG, TNF, TNFRSF1A
13
Show member pathways
9.2CD40LG, TNF, TNFRSF1A
149.2CD40LG, TNFRSF1A, TNFRSF1B
15
Show member pathways
8.9CD40LG, TNF, TNFRSF1A, TNFRSF1B
16
Show member pathways
8.9CD40LG, TNF, TNFRSF1A, TNFRSF1B
17
Show member pathways
8.9CD40LG, TNF, TNFRSF1A, TNFRSF1B
188.9CD40LG, HLA-DQB1, HLA-DRB1, MPZ
198.6CD40LG, CD79A, TNF, TNFRSF1A, TNFRSF1B
208.6HLA-DQB1, HLA-DRB1, TNF, TNFRSF1A
218.6HLA-DQB1, HLA-DRB1, TNF, TNFRSF1A
22
Show member pathways
8.2CD40LG, HLA-DQB1, HLA-DRB1, TNF, TNFRSF1A
23
Show member pathways
7.6CD40LG, CD79A, HLA-DQB1, HLA-DRB1, TNF, TNFRSF1A

GO Terms for genes affiliated with Guillain-Barre Syndrome

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Cellular components related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II protein complexGO:004261310.1HLA-DQB1, HLA-DRB1
2external side of plasma membraneGO:00098979.7CD40LG, CD79A, HLA-DRB1, TNF
3membrane raftGO:00451219.6CD79A, TNF, TNFRSF1A, TNFRSF1B
4myelin sheathGO:00432099.3ALB, MBP, MPZ, PMP2

Biological processes related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

(show all 14)
idNameGO IDScoreTop Affiliating Genes
1positive regulation of membrane protein ectodomain proteolysisGO:005104410.5TNF, TNFRSF1B
2regulation of immunoglobulin secretionGO:005102310.4CD40LG, TNF
3myelinationGO:004255210.4MBP, MPZ, PMP22
4death-inducing signaling complex assemblyGO:007155010.3TNF, TNFRSF1A
5antigen processing and presentation of peptide or polysaccharide antigen via MHC class IIGO:000250410.2HLA-DQB1, HLA-DRB1
6humoral immune response mediated by circulating immunoglobulinGO:000245510.2HLA-DQB1, HLA-DRB1
7positive regulation of ceramide biosynthetic processGO:200030410.2TNF, TNFRSF1A
8regulation of establishment of endothelial barrierGO:190314010.2TNF, TNFRSF1A
9immunoglobulin production involved in immunoglobulin mediated immune responseGO:000238110.1HLA-DQB1, HLA-DRB1
10intrinsic apoptotic signaling pathway in response to DNA damageGO:00086309.9TNF, TNFRSF1A, TNFRSF1B
11T cell costimulationGO:00312959.7CD40LG, HLA-DQB1, HLA-DRB1
12chemical synaptic transmissionGO:00072689.6HCRT, MBP, MPZ, PMP22
13tumor necrosis factor-mediated signaling pathwayGO:00332098.9CD40LG, TNF, TNFRSF1A, TNFRSF1B
14immune responseGO:00069558.3CD40LG, HLA-DQB1, HLA-DRB1, MBP, TNF, TNFRSF1A

Molecular functions related to Guillain-Barre Syndrome according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1MHC class II receptor activityGO:00323959.5HLA-DQB1, HLA-DRB1

Sources for Guillain-Barre Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet