MCID: GTT002
MIFTS: 36

Guttate Psoriasis malady

Rare diseases, Skin diseases, Gastrointestinal diseases categories

Summaries for Guttate Psoriasis

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NIH Rare Diseases:43 Guttate psoriasis is a skin condition in which small, red, and scaly teardrop-shaped spots appear on the arms, legs, and middle of the body. it is a relatively uncommon form of psoriasis. the condition often develops very suddenly, and is usually triggered by an infection (e.g., strep throat, bacteria infection, upper respiratory infections or other viral infections). other triggers include injury to the skin, including cuts, burns, and insect bites, certain malarial and heart medications, stress, sunburn, and excessive alcohol consumption. treatment depends on the severity of the symptoms, ranging from at-home over the counter remedies to medicines that suppress the body's immune system to sunlight and phototherapy.  last updated: 1/3/2013

MalaCards based summary: Guttate Psoriasis, also known as psoriasis guttate, is related to psoriasis and influenza. An important gene associated with Guttate Psoriasis is CDSN (corneodesmosin), and among its related pathways are Cell adhesion molecules (CAMs) and Allograft rejection. The compounds prednisolone and mannose have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and t cells, and related mouse phenotypes are tumorigenesis and immune system.

Wikipedia:65 Guttate psoriasis (also known as \"eruptive psoriasis\") is a type of psoriasis that presents as small... more...

Aliases & Classifications for Guttate Psoriasis

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Guttate Psoriasis, Aliases & Descriptions:

Name: Guttate Psoriasis 43 62
 
Psoriasis Guttate 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases, Gastrointestinal diseases


External Ids:

ICD1027 L40.4

Related Diseases for Guttate Psoriasis

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Diseases related to Guttate Psoriasis via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

(show all 42)
idRelated DiseaseScoreTop Affiliating Genes
1psoriasis31.6TRB, CDSN, NOD2, KIR2DS1, ITGAL, HLA-C
2influenza30.3ITGAL, TRB
3leukemia30.2HLA-C, ITGAL, TRB
4dermatitis10.4
5kawasaki disease10.3
6crohn's disease10.3
7rosacea10.2
8pityriasis rosea10.2
9scarlet fever10.2
10tonsillitis10.2
11chickenpox10.2
12balanoposthitis10.2
13sarcoma10.2
14pityriasis lichenoides10.2
15pityriasis lichenoides chronica10.2
16blindness10.2
17psoriatic arthritis10.0HLA-C
18psoriasis susceptibility 110.0HLA-C
19spondyloarthropathy 110.0HLA-C
20uveitis10.0HLA-C, NOD2
21atopic dermatitis10.0NOD2, CDSN
22pulmonary sarcoidosis10.0ITGAL, TRB
23mycosis fungoides10.0ITGAL, TRB
24cutaneous t cell lymphoma10.0TRB, ITGAL
25graft-versus-host disease, protection against10.0TRB, ITGAL
26cork-handlers' disease10.0HLA-C, ITGAL
27sjogren's syndrome10.0ITGAL, TRB
28neutropenia10.0TRB, ITGAL
29graves' disease10.0TRB, ITGAL
30precursor t-cell acute lymphoblastic leukemia10.0TRB, ITGAL
31chronic lymphocytic leukemia10.0ITGAL, TRB
32sarcoidosis 110.0HLA-C, NOD2, TRB
33arthritis10.0NOD2, TRB, HLA-C
34b-cell lymphomas10.0TRB, ITGAL
35congenital human immunodeficiency virus10.0TRB, ITGAL
36hepatitis b10.0TRB, ITGAL, HLA-C
37multiple sclerosis, disease progression, modifier of10.0HLA-C, TRB, ITGAL
38systemic lupus erythematosus10.0ITGAL, NOD2, TRB
39hypersensitivity reaction type ii disease10.0ITGAL, NOD2, TRB
40burkitt lymphoma10.0TRB, HLA-C, ITGAL
41rheumatoid arthritis10.0NOD2, TRB, ITGAL
42skin disease9.9CDSN, TRB, HLA-C, ITGAL

Graphical network of the top 20 diseases related to Guttate Psoriasis:



Diseases related to guttate psoriasis

Symptoms for Guttate Psoriasis

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Drugs & Therapeutics for Guttate Psoriasis

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Drug clinical trials:

Search ClinicalTrials for Guttate Psoriasis

Search NIH Clinical Center for Guttate Psoriasis

Genetic Tests for Guttate Psoriasis

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Anatomical Context for Guttate Psoriasis

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MalaCards organs/tissues related to Guttate Psoriasis:

33
Skin, Heart, T cells, Tonsil, Neutrophil

Animal Models for Guttate Psoriasis or affiliated genes

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MGI Mouse Phenotypes related to Guttate Psoriasis:

37
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00020068.4TRB, CDSN, ITGAL
2MP:00053878.3TRB, CDSN, NOD2, ITGAL

Publications for Guttate Psoriasis

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Articles related to Guttate Psoriasis:

(show top 50)    (show all 82)
idTitleAuthorsYear
1
Differentiation of pityriasis lichenoides chronica from guttate psoriasis by dermoscopy. (25682853)
2015
2
Localized guttate psoriasis in a patient with erythema migrans. (25350480)
2014
3
First presentation of guttate psoriasis triggered by acute tonsillitis. (25309672)
2014
4
Guttate psoriasis is associated with an intermediate phenotype of impaired Langerhans cell migration. (24628096)
2014
5
Expression patterns of Th1/Th2 transcription factors in patients with guttate psoriasis. (23827748)
2013
6
New Onset Guttate Psoriasis Following Pandemic H1N1 Influenza Vaccination. (24371399)
2013
7
Effects of Malassezia yeasts on serum Th1 and Th2 cytokines in patients with guttate psoriasis. (22512309)
2013
8
Rapid-onset skin rash. Guttate psoriasis. (22963026)
2012
9
Letter: A case of generalized guttate psoriasis induced by etanercept with relapse after abatacept. (21696691)
2011
10
The cholinergic system in guttate psoriasis with special reference to mast cells. (21521372)
2011
11
Guttate psoriasis occurring on varicella lesions. (20883381)
2010
12
Foxp3+ regulatory T cells and related cytokines differentially expressed in plaque vs. guttate psoriasis vulgaris. (20222932)
2010
13
To treat or not to treat? Management of guttate psoriasis and pityriasis rosea in patients with evidence of group A Streptococcal infection. (20232586)
2010
14
Images in emergency medicine. Guttate psoriasis. (19303510)
2009
15
Comparison of the Expression Profile of JunB, c-Jun, and S100A8 (Calgranulin A) in Psoriasis Vulgaris and Guttate Psoriasis. (20548852)
2009
16
Guttate psoriasis induced by infliximab in a child with Crohn's disease. (18383177)
2008
17
Efalizumab-induced guttate psoriasis. Successful management and re-treatment. (18569275)
2008
18
An investigation of antistreptococcal antibody responses in guttate psoriasis. (18648827)
2008
19
A 23-year-old Hispanic migrant fieldworker who presents with a painful rash on his limbs, trunk, and face. Guttate psoriasis. (17252683)
2007
20
Winnie the Pooh and psoriasis too: an isomorphic response of guttate psoriasis in a tattoo. (17958785)
2007
21
Guttate psoriasis. (16948384)
2006
22
Suit PUVA as an effective and safe modality of treatment in guttate psoriasis. (16987282)
2006
23
Distinct HLA-C/KIR genotype profile associates with guttate psoriasis. (16185272)
2005
24
Guttate psoriasis-like lesions following BCG vaccination. (15233196)
2004
25
Role of Pityrosporum ovale in guttate psoriasis. (12692367)
2003
26
A Crohn's disease-associated insertion polymorphism (3020insC) in the NOD2 gene is not associated with psoriasis vulgaris, palmo-plantar pustular psoriasis or guttate psoriasis. (12930309)
2003
27
Rifampicin monotherapy for acute guttate psoriasis-better avoided. (17664755)
2001
28
Psoriasis vulgaris and acute guttate psoriasis in a family. (11454089)
2001
29
Guttate psoriasis following Kawasaki disease. (11841639)
2001
30
Treatment of acute guttate psoriasis with rifampicin. (20877106)
2000
31
Hyporesponsiveness of peripheral blood lymphocytes to streptococcal superantigens in patients with guttate psoriasis: evidence for systemic stimulation of T cells with superantigens released from focally infecting Streptococcus pyogenes. (10482006)
1999
32
Corneodesmosin (MHC S) gene in guttate psoriasis. (10470726)
1999
33
How great is the risk of further psoriasis following a single episode of acute guttate psoriasis? (8651734)
1996
34
Perianal streptococcal dermatitis associated with guttate psoriasis and/or balanoposthitis: a study of five cases. (8041660)
1994
35
Photofibrosis: a further histopathological change induced by PUVA therapy via the mast cell in guttate psoriasis. Preliminary report. (8073822)
1994
36
Picture of the month. Acute guttate psoriasis. (8362797)
1993
37
Acute guttate psoriasis after streptococcal scarlet fever. (8302748)
1993
38
Immunoblotting of streptococcal antigens in guttate psoriasis. (8457448)
1993
39
A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis. Rapid improvement of clinical manifestations and changes in neutrophil leukotriene profile. (8219661)
1993
40
The role of streptococcal infection in the initiation of guttate psoriasis. (1739285)
1992
41
Acantholytic dyskeratotic epidermal naevus in a patient with guttate psoriasis on PUVA therapy. (2064947)
1991
42
Guttate psoriasis and vitiligo: anatomic cohabitation. (2715422)
1989
43
Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris. (6512269)
1984
44
Prominent fungiform papillae in guttate psoriasis. (6585222)
1984
45
Two sisters with guttate psoriasis responsive to tonsillectomy: case reports with HLA studies. (393748)
1979
46
Unspecific increase of antistreptolysin-O titer in acute guttate psoriasis. (15461348)
1977
47
HL-A antigens in patients with guttate psoriasis. (952752)
1976
48
Leukemia cutis masquerading as guttate psoriasis. (4517122)
1973
49
Guttate psoriasis. (4639263)
1972
50
ACUTE GUTTATE PSORIASIS AND STREPTOCOCCAL INFECTION. (14096349)
1964

Variations for Guttate Psoriasis

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Expression for genes affiliated with Guttate Psoriasis

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Search GEO for disease gene expression data for Guttate Psoriasis.

Pathways for genes affiliated with Guttate Psoriasis

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Compounds for genes affiliated with Guttate Psoriasis

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Sources:
45Novoseek, 30IUPHAR, 13DrugBank, 51PharmGKB
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Compounds related to Guttate Psoriasis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1prednisolone45 30 1311.6NOD2, ITGAL
2mannose459.5ITGAL, NOD2
3tacrolimus45 51 1311.5NOD2, ITGAL
4phorbol459.3TRB, ITGAL
5endotoxin459.2NOD2, ITGAL
6cyclophosphamide45 51 1311.0TRB, ITGAL
7threonine458.7TRB, NOD2, ITGAL

GO Terms for genes affiliated with Guttate Psoriasis

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Biological processes related to Guttate Psoriasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1innate immune responseGO:00450878.9NOD2, KIR2DS1, HLA-C
2regulation of immune responseGO:00507768.5KIR2DS1, ITGAL, HLA-C

Products for genes affiliated with Guttate Psoriasis

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Sources for Guttate Psoriasis

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet