MCID: GTT002
MIFTS: 25

Guttate Psoriasis malady

Skin, Gastrointestinal categories

Summaries for Guttate Psoriasis

Sources:
43NIH Rare Diseases, 33MalaCards
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NIH Rare Diseases:43 Guttate psoriasis is a skin condition in which small, red, and scaly teardrop-shaped spots appear on the arms, legs, and middle of the body. it is a relatively uncommon form of psoriasis. the condition often develops very suddenly, and is usually triggered by an infection (e.g., strep throat, bacteria infection, upper respiratory infections or other viral infections). other triggers include injury to the skin, including cuts, burns, and insect bites, certain malarial and heart medications, stress, sunburn, and excessive alcohol consumption. treatment depends on the severity of the symptoms, ranging from at-home over the counter remedies to medicines that suppress the body's immune system to sunlight and phototherapy.  last updated: 1/3/2013

MalaCards: Guttate Psoriasis, also known as psoriasis guttate, is related to kawasaki disease and balanoposthitis. An important gene associated with Guttate Psoriasis is CDSN (corneodesmosin), and among its related pathways are Immune response Antigen presentation by MHC class I and Classical antibody-mediated complement activation. The compounds prednisolone and phorbol have been mentioned in the context of this disorder. Affiliated tissues include skin, heart and t cells.

Aliases & Classifications for Guttate Psoriasis

Sources:
43NIH Rare Diseases, 61UMLS, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin, Gastrointestinal


Aliases & Descriptions:

guttate psoriasis 43 61
psoriasis guttate 43


External Ids:

ICD1025 L40.4

Related Diseases for Guttate Psoriasis

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Guttate Psoriasis:



Diseases related to guttate psoriasis

Clinical Features for Guttate Psoriasis

Drugs & Therapeutics for Guttate Psoriasis

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

Search CenterWatch for Guttate Psoriasis

Drug clinical trials:

Search ClinicalTrials for Guttate Psoriasis

Search NIH Clinical Center for Guttate Psoriasis

Search CenterWatch for Guttate Psoriasis

Genetic Tests for Guttate Psoriasis

Anatomical Context for Guttate Psoriasis

Sources:
33MalaCards
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MalaCards organs/tissues related to Guttate Psoriasis:

33
Skin, Heart, T cells

Animal Models for Guttate Psoriasis or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Guttate Psoriasis

Sources:
51PubMed
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Articles related to Guttate Psoriasis:

(show top 50)    (show all 77)
idTitleAuthorsYear
1
Expression patterns of Th1/Th2 transcription factors in patients with guttate psoriasis. (23827748)
2013
2
New Onset Guttate Psoriasis Following Pandemic H1N1 Influenza Vaccination. (24371399)
2013
3
Effects of Malassezia yeasts on serum Th1 and Th2 cytokines in patients with guttate psoriasis. (22512309)
2013
4
Rapid-onset skin rash. Guttate psoriasis. (22963026)
2012
5
Acute guttate psoriasis in a 15-year-old girl with Epstein-Barr virus infection. (22782168)
2012
6
Letter: A case of generalized guttate psoriasis induced by etanercept with relapse after abatacept. (21696691)
2011
7
The cholinergic system in guttate psoriasis with special reference to mast cells. (21521372)
2011
8
Dermacase. Can you identify this condition? Guttate psoriasis. (21252134)
2011
9
Foxp3+ regulatory T cells and related cytokines differentially expressed in plaque vs. guttate psoriasis vulgaris. (20222932)
2010
10
To treat or not to treat? Management of guttate psoriasis and pityriasis rosea in patients with evidence of group A Streptococcal infection. (20232586)
2010
11
Images in emergency medicine. Guttate psoriasis. (19303510)
2009
12
Comparison of the Expression Profile of JunB, c-Jun, and S100A8 (Calgranulin A) in Psoriasis Vulgaris and Guttate Psoriasis. (20548852)
2009
13
Guttate psoriasis triggered by chickenpox. (19755956)
2009
14
Guttate psoriasis induced by infliximab in a child with Crohn's disease. (18383177)
2008
15
Efalizumab-induced guttate psoriasis. Successful management and re-treatment. (18569275)
2008
16
Antistreptococcal treatment of guttate psoriasis: a controlled study. (18937661)
2008
17
A 23-year-old Hispanic migrant fieldworker who presents with a painful rash on his limbs, trunk, and face. Guttate psoriasis. (17252683)
2007
18
Guttate psoriasis. (16948384)
2006
19
Distinct HLA-C/KIR genotype profile associates with guttate psoriasis. (16185272)
2005
20
Treatment of guttate psoriasis with a new two-compound product containing calcipotriol and betamethasone dipropionate. (16402632)
2005
21
Acute guttate psoriasis patients have positive streptococcus hemolyticus throat cultures and elevated antistreptococcal M6 protein titers. (15906537)
2005
22
Guttate psoriasis following Ecstasy ingestion. (15250894)
2004
23
Role of Pityrosporum ovale in guttate psoriasis. (12692367)
2003
24
A Crohn's disease-associated insertion polymorphism (3020insC) in the NOD2 gene is not associated with psoriasis vulgaris, palmo-plantar pustular psoriasis or guttate psoriasis. (12930309)
2003
25
Psoriasis vulgaris and acute guttate psoriasis in a family. (11454089)
2001
26
Guttate psoriasis following Kawasaki disease. (11841639)
2001
27
Family history of psoriasis, stressful life events, and recent infectious disease are risk factors for a first episode of acute guttate psoriasis: results of a case-control study. (11209111)
2001
28
A case of guttate psoriasis following Kawasaki disease. (10735970)
2000
29
Interventions for guttate psoriasis. (10796758)
2000
30
Guttate psoriasis triggered by perianal streptococcal dermatitis in a four-year-old boy. (10767696)
2000
31
HLA-C and guttate psoriasis. (11122018)
2000
32
Hyporesponsiveness of peripheral blood lymphocytes to streptococcal superantigens in patients with guttate psoriasis: evidence for systemic stimulation of T cells with superantigens released from focally infecting Streptococcus pyogenes. (10482006)
1999
33
Recognition of Streptococcus pyogenes and skin autoantigens in guttate psoriasis. (9650329)
1998
34
Evidence for a streptococcal superantigen-driven process in acute guttate psoriasis. (7593594)
1995
35
Perianal streptococcal dermatitis associated with guttate psoriasis and/or balanoposthitis: a study of five cases. (8041660)
1994
36
Photofibrosis: a further histopathological change induced by PUVA therapy via the mast cell in guttate psoriasis. Preliminary report. (8073822)
1994
37
Acute guttate psoriasis after streptococcal scarlet fever. (8302748)
1993
38
A double-blind, randomized, placebo-controlled trial of n-3 fatty acid based lipid infusion in acute, extended guttate psoriasis. Rapid improvement of clinical manifestations and changes in neutrophil leukotriene profile. (8219661)
1993
39
Guttate psoriasis. (8444046)
1993
40
The role of streptococcal infection in the initiation of guttate psoriasis. (1739285)
1992
41
Acantholytic dyskeratotic epidermal naevus in a patient with guttate psoriasis on PUVA therapy. (2064947)
1991
42
A family outbreak of acute guttate psoriasis. (2241216)
1990
43
Guttate psoriasis associated with perianal streptococcal disease. (3057157)
1988
44
Mast cell degranulation in the evolution of acute eruptive guttate psoriasis vulgaris. (6512269)
1984
45
Prominent fungiform papillae in guttate psoriasis. (6585222)
1984
46
Dermal and epidermal involvement in the evolution of acute eruptive guttate psoriasis vulgaris. (6512270)
1984
47
Two sisters with guttate psoriasis responsive to tonsillectomy: case reports with HLA studies. (393748)
1979
48
Alterations of clinically normal skin in early eruptive guttate psoriasis. A light- and electron-microscopic study. (730863)
1978
49
Unspecific increase of antistreptolysin-O titer in acute guttate psoriasis. (15461348)
1977
50
Leukemia cutis masquerading as guttate psoriasis. (4517122)
1973

Genetic Variations for Guttate Psoriasis

Expression for genes affiliated with Guttate Psoriasis

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Guttate Psoriasis

Search GEO for disease gene expression data for Guttate Psoriasis.

Pathways for genes affiliated with Guttate Psoriasis

Sources:
12EMD Millipore, 54Reactome, 30KEGG
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Compounds for genes affiliated with Guttate Psoriasis

Sources:
45Novoseek, 29IUPHAR, 11DrugBank
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Compounds related to Guttate Psoriasis according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1prednisolone45 29 1111.2NOD2, ITGAL
2phorbol458.8TRB, ITGAL

GO Terms for genes affiliated with Guttate Psoriasis

Sources:
16Gene Ontology
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Biological processes related to Guttate Psoriasis according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1innate immune responseGO:0450878.9NOD2, KIR2DS1, HLA-C
2regulation of immune responseGO:0507768.2KIR2DS1, ITGAL, HLA-C

Products for genes affiliated with Guttate Psoriasis

  • Antibodies
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  • Antibodies

Sources for Guttate Psoriasis

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet