MCID: GTT002
MIFTS: 31

Guttate Psoriasis malady

Categories: Rare diseases, Skin diseases, Gastrointestinal diseases

Aliases & Classifications for Guttate Psoriasis

About this section

Aliases & Descriptions for Guttate Psoriasis:

Name: Guttate Psoriasis 45 65
 
Psoriasis Guttate 45

Classifications:



External Ids:

ICD1027 L40.4
UMLS65 C0343052

Summaries for Guttate Psoriasis

About this section
NIH Rare Diseases:45 Guttate psoriasis is a skin condition in which small, red, and scaly teardrop-shaped spots appear on the arms, legs, and middle of the body. it is a relatively uncommon form of psoriasis. the condition often develops very suddenly, and is usually triggered by an infection (e.g., strep throat, bacteria infection, upper respiratory infections or other viral infections). other triggers include injury to the skin, including cuts, burns, and insect bites, certain malarial and heart medications, stress, sunburn, and excessive alcohol consumption. treatment depends on the severity of the symptoms, ranging from at-home over the counter remedies to medicines that suppress the body's immune system to sunlight and phototherapy.  last updated: 1/3/2013

MalaCards based summary: Guttate Psoriasis, also known as psoriasis guttate, is related to pancreatitis and obesity. An important gene associated with Guttate Psoriasis is CDSN (Corneodesmosin), and among its related pathways are Tuberculosis and Cell adhesion molecules (CAMs). Affiliated tissues include skin, heart and breast.

Wikipedia:68 Guttate psoriasis (also known as eruptive psoriasis) is a type of psoriasis that presents as small... more...

Related Diseases for Guttate Psoriasis

About this section

Graphical network of the top 20 diseases related to Guttate Psoriasis:



Diseases related to guttate psoriasis

Symptoms for Guttate Psoriasis

About this section

Drugs & Therapeutics for Guttate Psoriasis

About this section

Drugs for Guttate Psoriasis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
TofacitinibapprovedPhase 395477600-75-2
Synonyms:
Tasocitinib
 
Tofacitinib Citrate
Tofacitinibum
Xeljanz
2Protein Kinase InhibitorsPhase 33162

Interventional clinical trials:

idNameStatusNCT IDPhase
1A Study To Evaluate The Effects And Safety Of Treatment, Treatment Withdrawal, Followed By Re-Treatment With CP-690,550 In Subjects With Moderate To Severe Chronic Plaque PsoriasisCompletedNCT01186744Phase 3
2The Effect of Algae Dunaliella Bardawil on Psoriasis (2)WithdrawnNCT01121081Phase 3
3Determination of the Efficacy and Safety of Psirelax in the Relief of the Disease in PsoriasisCompletedNCT01000714Phase 2

Search NIH Clinical Center for Guttate Psoriasis

Genetic Tests for Guttate Psoriasis

About this section

Anatomical Context for Guttate Psoriasis

About this section

MalaCards organs/tissues related to Guttate Psoriasis:

33
Skin, Heart, Breast, Endothelial, T cells, Liver, Neutrophil

Animal Models for Guttate Psoriasis or affiliated genes

About this section

MGI Mouse Phenotypes related to Guttate Psoriasis:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Guttate Psoriasis

About this section

Articles related to Guttate Psoriasis:

(show top 50)    (show all 84)
idTitleAuthorsYear
1
In Epstein-Barr virus-associated gastric carcinoma a high density of CD66b-positive tumor-associated neutrophils is associated with intestinal-type histology and low frequency of lymph node metastasis. (26915031)
2016
2
Cronkhite-Canada Syndrome (CCS)-A Rare Case Report. (25954656)
2015
3
Pazopanib for recurrent extraosseous Ewing's sarcoma of the retroperitoneum. (25040171)
2014
4
A founder SDHB mutation in Portuguese paraganglioma patients. (24092654)
2013
5
Giant gastrointestinal stromal tumor (GIST) of the stomach cause of high bowel obstruction: surgical management. (23914945)
2013
6
Nevoid basal cell carcinoma syndrome: a 40-year study in the South African population. (22742575)
2013
7
Cobalt chloride inhibits tumor formation in osteosarcoma cells through upregulation of HIF-1I+ (23426939)
2013
8
Shigellosis in Bay of Bengal Islands, India: clinical and seasonal patterns, surveillance of antibiotic susceptibility patterns, and molecular characterization of multidrug-resistant Shigella strains isolated during a 6-year period from 2006 to 2011. (23990135)
2013
9
Malignant nature of cardiac liposarcoma revealed by fluorine-18 fluorodeoxyglucose positron emission tomographic imaging. (22687843)
2012
10
Pralatrexate: a novel synthetic antifolate for relapsed or refractory peripheral T-cell lymphoma and other potential uses. (21956523)
2012
11
Video assisted trans-cervical thymectomy A minimally invasive approach to treat non-thymomatous myasthenia gravis. (23282409)
2012
12
Angiomyolipoma manifested as accessory kidney mass. (21426896)
2011
13
The opioid systems--panacea and nemesis. (20494127)
2010
14
Sgs1 function in the repair of DNA replication intermediates is separable from its role in homologous recombinational repair. (19214189)
2009
15
Protocadherin PCDH10, involved in tumor progression, is a frequent and early target of promoter hypermethylation in cervical cancer. (19681120)
2009
16
Increased damage of exon 5 of p53 gene in workers from an arsenic plant. (18621066)
2008
17
Acute hemodynamic effects of tolvaptan, a vasopressin V2 receptor blocker, in patients with symptomatic heart failure and systolic dysfunction: an international, multicenter, randomized, placebo-controlled trial. (19007589)
2008
18
Rescue of migratory defects of Ehlers-Danlos syndrome fibroblasts in vitro by type V collagen but not insulin-like binding protein-1. (18305566)
2008
19
Tear function and ocular surface changes in multinodular goiter patients. (17579293)
2007
20
Inhibition of Aurora-B function increases formation of multinucleated cells in p53 gene deficient cells and enhances anti-tumor effect of temozolomide in human glioma cells. (17570035)
2007
21
Common variants in WFS1 confer risk of type 2 diabetes. (17603484)
2007
22
Distinctive T cell-suppressive signals from nuclearized type 1 sphingosine 1-phosphate G protein-coupled receptors. (17121832)
2007
23
Regulation of vascular endothelial growth factor expression and vascularization in the myocardium by insulin receptor and PI3K/Akt pathways in insulin resistance and ischemia. (16469952)
2006
24
Preclinical antitumor activity of BMS-599626, a pan-HER kinase inhibitor that inhibits HER1/HER2 homodimer and heterodimer signaling. (17062696)
2006
25
Overexpression of PIAS3 suppresses cell growth and restores the drug sensitivity of human lung cancer cells in association with PI3-K/Akt inactivation. (17032498)
2006
26
A-425619 [1-isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea], a novel transient receptor potential type V1 receptor antagonist, relieves pathophysiological pain associated with inflammation and tissue injury in rats. (15837818)
2005
27
Protective role of BCG vaccination against tuberculous meningitis in Indian children: a reappraisal. (15835483)
2005
28
Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker. (14765974)
2004
29
ERK1/2 mediates TNF-alpha-induced matrix metalloproteinase-9 expression in human vascular smooth muscle cells via the regulation of NF-kappaB and AP-1: Involvement of the ras dependent pathway. (14755547)
2004
30
Poly-ubiquitin binding by the polyglutamine disease protein ataxin-3 links its normal function to protein surveillance pathways. (14602712)
2004
31
Oxygen-evoked changes in transcriptional activity of the 5'-flanking region of the human amiloride-sensitive sodium channel (alphaENaC) gene: role of nuclear factor kappaB. (12023897)
2002
32
Severe protein C deficiency and aseptic osteonecrosis of the hip joint: a case report. (10650859)
1999
33
An outbreak of aseptic meningitis due to ECHO 30 virus in Romania during the 1999 summer. (11601385)
1999
34
Juvenile hyaline fibromatosis: a case report. (9702677)
1998
35
The possible role of apoptosis-suppressing genes, bcl-2 and mcl-1/EAT in human adrenal tumors. (9888605)
1998
36
The PAH mutation analysis consortium database: update 1996. (9016524)
1997
37
The activated metabolites of hepatocarcinogens are involved in the disruption of tyrosine aminotransferase induction by glucocorticoids]. (9471273)
1997
38
Cytokinetic investigations in human breast cancer by flow cytometrically recorded DNA/protein distributions. (8789270)
1996
39
Successful treatment by surgical removal of bone metastasis producing PTH: new approach to the management of metastatic parathyroid carcinoma. (7849385)
1994
40
Breast cancer and fenretinide, an analogue of vitamin A. (7808027)
1994
41
Mapping of the Bacillus subtilis cspB gene and cloning of its homologs in thermophilic, mesophilic and psychrotrophic bacilli. (8294017)
1993
42
Binding of lipoprotein lipase to heparin. Identification of five critical residues in two distinct segments of the amino-terminal domain. (8473288)
1993
43
Survey of antimicrobial resistance to oral antibiotics in Italy. (8444057)
1993
44
Symptomatic congenital cytomegalovirus infection: neonatal morbidity and mortality. (1311066)
1992
45
Acquired pseudo-mongolian spot associated with minocycline therapy. (1580671)
1992
46
Assessment of a school exclusion policy during a chickenpox outbreak. (2035519)
1991
47
Pathophysiologic events related to thermal injury of skin. (2254996)
1990
48
Dental treatment of a patient with congenital afibrinogenemia--complications of supportive care. (6461847)
1981
49
An unusual case of local gigantism. (1070992)
1976
50
A case of human ornithosis presenting as an obscure febrile illness associated with macular rash. (13952980)
1963

Variations for Guttate Psoriasis

About this section

Expression for genes affiliated with Guttate Psoriasis

About this section
Search GEO for disease gene expression data for Guttate Psoriasis.

Pathways for genes affiliated with Guttate Psoriasis

About this section

GO Terms for genes affiliated with Guttate Psoriasis

About this section

Biological processes related to Guttate Psoriasis according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1regulation of immune responseGO:00507769.5ITGAL, KIR2DS1
2single organismal cell-cell adhesionGO:00163379.5CDSN, ITGAL
3defense response to bacteriumGO:00427429.0CAMP, NOD2
4innate immune responseGO:00450878.8CAMP, KIR2DS1, NOD2

Sources for Guttate Psoriasis

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet