MCID: GYN003
MIFTS: 26

Gynandroblastoma malady

Categories: Rare diseases, Reproductive diseases

Aliases & Classifications for Gynandroblastoma

Summaries for Gynandroblastoma

MalaCards based summary : Gynandroblastoma, also known as ovarian gynandroblastoma, is related to liver angiosarcoma and nipple neoplasm. An important gene associated with Gynandroblastoma is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways is MicroRNAs in cancer. The drugs Paclitaxel and Bleomycin have been mentioned in the context of this disorder. Affiliated tissues include ovary and testis.

Related Diseases for Gynandroblastoma

Graphical network of the top 20 diseases related to Gynandroblastoma:



Diseases related to Gynandroblastoma

Symptoms & Phenotypes for Gynandroblastoma

Drugs & Therapeutics for Gynandroblastoma

Drugs for Gynandroblastoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 26)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Paclitaxel Approved, Vet_approved Phase 2 33069-62-4 36314
2
Bleomycin Approved Phase 2 11056-06-7 5360373
3
Carboplatin Approved Phase 2 41575-94-4 10339178 498142 38904
4
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
5
Etoposide Approved Phase 2 33419-42-0 36462
6
Succinylcholine Approved Phase 2 306-40-1 5314
7
Bevacizumab Approved, Investigational Phase 2 216974-75-3
8 Albumin-Bound Paclitaxel Phase 2
9 Antimitotic Agents Phase 2
10 Antineoplastic Agents, Phytogenic Phase 2
11 Anti-Bacterial Agents Phase 2
12 Antibiotics, Antitubercular Phase 2
13 Etoposide phosphate Phase 2
14 Neuromuscular Agents Phase 2
15 Neuromuscular Blocking Agents Phase 2
16 Neuromuscular Depolarizing Agents Phase 2
17 Peripheral Nervous System Agents Phase 2
18 Topoisomerase Inhibitors Phase 2
19 Angiogenesis Inhibitors Phase 2
20 Angiogenesis Modulating Agents Phase 2
21 Antibodies Phase 2
22 Antibodies, Monoclonal Phase 2
23 Endothelial Growth Factors Phase 2
24 Immunoglobulin G Phase 2
25 Immunoglobulins Phase 2
26 Mitogens Phase 2

Interventional clinical trials:


id Name Status NCT ID Phase
1 Paclitaxel in Treating Patients With Ovarian Stromal Cancer Completed NCT00006227 Phase 2
2 Paclitaxel and Carboplatin or Bleomycin Sulfate, Etoposide Phosphate, and Cisplatin in Treating Patients With Advanced or Recurrent Sex Cord-Ovarian Stromal Tumors Recruiting NCT01042522 Phase 2
3 Bevacizumab in Treating Patients With Recurrent Sex Cord-Stromal Tumors of the Ovary Active, not recruiting NCT00748657 Phase 2
4 International Ovarian & Testicular Stromal Tumor Registry Recruiting NCT01970696

Search NIH Clinical Center for Gynandroblastoma

Genetic Tests for Gynandroblastoma

Anatomical Context for Gynandroblastoma

MalaCards organs/tissues related to Gynandroblastoma:

39
Ovary, Testis

Publications for Gynandroblastoma

Articles related to Gynandroblastoma:

(show all 37)
id Title Authors Year
1
Gynandroblastoma with a Juvenile Granulosa Cell Component in an Adolescent: Case Report and Literature Review. ( 27751908 )
2016
2
Gynandroblastoma With Juvenile Granulosa Cell Tumor and Concurrent Renal Cell Carcinoma: A Case Report and Review of Literature. ( 26169919 )
2015
3
Gynandroblastoma: a rare ovarian tumour with an unusual clinical presentation. ( 25935975 )
2014
4
Androgen insensitivity syndrome with gynandroblastoma and vulvar leiomyoma: case report and literature review. ( 23552209 )
2013
5
The C134W (402 C>G) FOXL2 mutation is absent in ovarian gynandroblastoma: insights into the genesis of an unusual tumour. ( 22296244 )
2012
6
Gynandroblastoma with the symptoms of infertility and secondary amenorrhea: a case report. ( 22268290 )
2011
7
Gynandroblastoma. Report of an unusual ovarian tumour and literature review. ( 18686520 )
2008
8
Recurrent gynandroblastoma of ovary-A case report: a molecular and immunohistochemical analysis. ( 17197894 )
2007
9
A cystic mass in a young woman with presumed polycystic ovarian syndrome. Gynandroblastoma. ( 16454570 )
2006
10
Ovarian gynandroblastoma with juvenile granulosa cell component and raised alpha fetoprotein. ( 16194833 )
2005
11
Gynandroblastoma of the testis in an infant: a morphological, immunohistochemical and in-situ hybridization report. ( 11943029 )
2002
12
Gynandroblastoma in pregnancy: case report and review of literature. ( 9757751 )
1998
13
Gynandroblastoma with elements of juvenile granulosa cell tumor. ( 9553819 )
1998
14
Gynandroblastoma of the ovary: a case report with an immunohistochemical and ultrastructural study. ( 9037319 )
1997
15
Gynandroblastoma with elements resembling juvenile granulosa cell tumor. ( 9421080 )
1997
16
Gynandroblastoma of ovary with juvenile granulosa cell component and heterologous intestinal type glands. ( 8884354 )
1996
17
Gynandroblastoma of the ovary having a typical morphological appearance: a case study. ( 2067122 )
1991
18
Gynandroblastoma of the ovary. A case report. ( 1879200 )
1991
19
Gynandroblastoma of the ovary. ( 3785986 )
1986
20
Granulosa cell tumor of the ovary with Sertoli-Leydig cell tumor components (gynandroblastoma). ( 4056537 )
1985
21
Gynandroblastoma of the ovary. ( 6224079 )
1983
22
Gynandroblastoma: its ultrastructure. ( 6284338 )
1982
23
Hormone studies in a gynandroblastoma. ( 658481 )
1978
24
Gynandroblastoma of the ovary. ( 1169960 )
1975
25
Gynandroblastoma of the ovary. ( 4846779 )
1974
26
Ovarian gynandroblastoma presenting with primary amenorrhea. ( 4744425 )
1973
27
Plasma steroids in two subjects with ovarian androgen-producing tumors arrhenoblastoma and gynandroblastoma. ( 4334770 )
1972
28
Spontaneous rupture of gynandroblastoma during labor. Report of a case. ( 5474001 )
1970
29
Pleomorphic granulosa-cell tumor. A borderline case resembling gynandroblastoma. ( 6017934 )
1967
30
Gynandroblastoma of the ovary: review of 8 cases from the ovarian tumor registry. ( 4293230 )
1967
31
GYNANDROBLASTOMA. REPORT OF A CASE FOLLOWED BY VAGINAL CYTOLOGY. ( 14085616 )
1963
32
Gynandroblastoma. A report of five cases, with a discussion of the histogenesis and classification of ovarian tumors. ( 14479145 )
1962
33
Gynandroblastoma of the ovary; review and report of a case. ( 13633117 )
1959
34
Case report of gynandroblastoma. ( 13606189 )
1959
35
Feminizing ovarian gynandroblastoma. ( 13627065 )
1959
36
Gynandroblastoma of the ovary. ( 18103140 )
1949
37
Gynandroblastoma of the Ovary. ( 19970711 )
1943

Variations for Gynandroblastoma

Expression for Gynandroblastoma

Search GEO for disease gene expression data for Gynandroblastoma.

Pathways for Gynandroblastoma

Pathways related to Gynandroblastoma according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1 11.1 DICER1 VIM

GO Terms for Gynandroblastoma

Molecular functions related to Gynandroblastoma according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 double-stranded RNA binding GO:0003725 8.62 DICER1 VIM

Sources for Gynandroblastoma

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9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
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28 GO
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30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
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48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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