MCID: GYN001
MIFTS: 48

Gynecomastia malady

Category: Endocrine diseases

Aliases & Classifications for Gynecomastia

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Aliases & Descriptions for Gynecomastia:

Name: Gynecomastia 11 27 50 13 68

Classifications:



External Ids:

Disease Ontology11 DOID:12698
ICD1030 N62
MeSH39 D006177
NCIt45 C3073

Summaries for Gynecomastia

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Wikipedia:71 Gynecomastia is a common disorder of the endocrine system in which there is a non-cancerous increase in... more...

MalaCards based summary: Gynecomastia is related to pseudohermaphroditism, male, with gynecomastia and aromatase excess syndrome. An important gene associated with Gynecomastia is HSD17B3 (Hydroxysteroid 17-Beta Dehydrogenase 3), and among its related pathways are Aromatase Inhibitor Pathway (Breast Cell), Pharmacodynamics and Ovarian Infertility Genes. The drugs tamoxifen and tamoxifen citrate have been mentioned in the context of this disorder. Affiliated tissues include breast, prostate and skin, and related mouse phenotypes are integument and neoplasm.

Related Diseases for Gynecomastia

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Diseases related to Gynecomastia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50)    (show all 242)
idRelated DiseaseScoreTop Affiliating Genes
1pseudohermaphroditism, male, with gynecomastia12.1
2aromatase excess syndrome11.9
3infant gynecomastia11.9
4wilson-turner syndrome11.6
5spinal and bulbar muscular atrophy of kennedy11.1
6androgen insensitivity11.1
7androgen insensitivity, partial, with or without breast cancer10.9
8mental retardation-hypotonic facies syndrome, x-linked10.8
9mental retardation, x-linked, syndromic, wilson-turner type10.8
10alopecia, neurologic defects, and endocrinopathy syndrome10.7
11borjeson-forssman-lehmann syndrome10.7
12klinefelter's syndrome10.7
1346,xx testicular disorder of sex development10.7
1449, xxxyy syndrome10.7
15bartholin's gland benign neoplasm10.3ESR1, PGR
16cardiovascular organ benign neoplasm10.3ESR1, PGR
17appendix leiomyoma10.3ESR1, PGR
18bronchus adenoma10.3ESR1, PGR
19glioma10.3ESR1, PGR
20ovarian benign neoplasm10.3ESR1, PGR
21plexiform neurofibroma10.3ESR1, PGR
22paranasal sinus disease10.3ESR1, PGR
23skin sarcoma10.3PGR, PRL
24parathyroid adenoma10.3PRL, SRY
25borderline personality disorder10.3AR, CYP19A1
26deafness, autosomal recessive 2110.3ESR1, PGR
27abdominal aortic aneurysm10.3PRL, SRY
28cervical lymphoepithelioma-like carcinoma10.3ESR1, PGR
29histiocytic and dendritic cell cancer10.3ESR1, PGR
30atypical lipomatous tumor10.2ESR1, PGR
31x-linked leigh syndrome10.2AR, ESR1
32pediatric intraocular retinoblastoma10.2ESR1, PGR
33hole retinal cyst10.2AR, KLK3
34congenital disorder of glycosylation, type ic10.2ESR1, PGR
35intestinal perforation10.2ESR1, PGR
36perlman syndrome10.2ESR1, PGR
37biemond syndrome10.2CYP19A1, PGR
38gastric teratoma10.2PRL, SRY
39polyneuropathy10.2CYP19A1, SHBG
40bladder adenocarcinoma10.2ESR1, PGR
41third ventricle chordoid glioma10.2AR, CYP19A1, HSD17B3
42colon signet ring adenocarcinoma10.2AR, KLK3
43limbic encephalitis10.2CGA, HSD17B3
44panophthalmitis10.2CYP19A1, PGR
45vulva basal cell carcinoma10.2ESR1, PGR
46villoglandular endometrial endometrioid adenocarcinoma10.2ESR1, PGR
47vaginal adenosarcoma10.2ESR1, PGR
48intraneural perineurioma10.2ESR1, PGR
49benign shuddering attacks10.2AR, CYP19A1, ESR1
50her2-receptor negative breast cancer10.2CYP19A1, ESR1, PGR

Graphical network of the top 20 diseases related to Gynecomastia:



Diseases related to gynecomastia

Symptoms & Phenotypes for Gynecomastia

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MGI Mouse Phenotypes related to Gynecomastia according to GeneCards Suite gene sharing:

41
idDescriptionMGI Source AccessionScoreTop Affiliating Genes
1MP:00107718.3AR, CYP19A1, ESR1, PGR, POMC, PRL
2MP:00020067.9AR, ESR1, PGR, POMC, PRL
3MP:00053797.8AR, CGA, CYP19A1, ESR1, PGR, POMC

Drugs & Therapeutics for Gynecomastia

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Drugs for Gynecomastia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 36)
idNameStatusPhaseClinical TrialsCas NumberPubChem Id
1
BicalutamideapprovedPhase 4, Phase 3, Phase 217690357-06-556069, 2375
Synonyms:
(+-)-4'-Cyano-alpha,alpha,alpha-trifluoro-3-((p-fluorophenyl)sulfonyl)-2-methyl-m-lactotoluidide
4'-cyano-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methyl-3'-(trifluoromethyl)propionanilide
90357-06-5
AC-4232
AC1L1DJE
Astra brand of bicalutamide
AstraZeneca brand of bicalutamide
BRN 5364666
Bicalutamida
Bicalutamide
Bicalutamide (JAN/USP/INN)
Bicalutamide [USAN:INN:BAN]
Bicalutamidum
C053541
C08160
C18H14F4N2O4S
CHEMBL409
CID2375
CPD000466329
Casodex
Casodex (TN)
Casodex, Cosudex, Calutide, Kalumid, Bicalutamide
Cosudex
D00961
DB01128
 
FT-0080576
HMS2051B13
HMS2089N12
I06-0475
I06-0480
ICI 176334
ICI-176334
KS-1161
LS-119125
MLS000759437
MLS001424047
MolPort-003-845-034
MolPort-006-808-679
N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methylpropanamide
NCGC00167977-01
NCGC00167977-02
NSC722665
Propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,
Raffolutil
S1190_Selleck
SAM001246612
SMR000466329
TL8005814
Zeneca brand of bicalutamide
bicalutamide
propanamide, N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methyl-,(+-)
2Androgen AntagonistsPhase 4, Phase 3, Phase 2320
3HormonesPhase 4, Phase 3, Phase 2, Phase 114415
4Hormones, Hormone Substitutes, and Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113168
5Hormone AntagonistsPhase 4, Phase 3, Phase 2, Phase 113180
6AndrogensPhase 4, Phase 3, Phase 21321
7
TamoxifenapprovedPhase 3, Phase 239010540-29-12733526
Synonyms:
(Z)-1-(p-Dimethylaminoethoxyphenyl)-1,2-diphenyl-1-butene
(Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(4-(1,2-diphenylbut-1-enyl)phenoxy)-N,N-dimethylethanamine
(Z)-2-(Para-(1,2-diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine
(Z)-2-(para-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylamine (IUPAC)
(Z)-2-[4-(1,2)-DIPHENYL-1-BUTENYL)-PHENOXY]-N,N-DIMETHYLETHANAMINE
(Z)-2-[p-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
,citrate
1-P-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-Para-beta-dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-.beta.-Dimethylamino-ethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
1-para-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene
10540-29-1
1ya4
2-[4-[(Z)-1,2-diphenylbut-1-enyl]phenoxy]-N,N-dimethylethanamine
2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}-N,N-dimethylethanamine
54965-24-1 (citrate)
AC1MBZ3R
Apo-Tamox
Apo-tamox
BIDD:ER0008
BIDD:GT0009
BIDD:PXR0003
BPBio1_000278
BRD-K93754473-001-02-9
BRD-K93754473-048-05-3
BSPBio_000252
BSPBio_001150
BSPBio_001982
C07108
C26H29NO
CCRIS 3275
CHEBI:41774
CHEMBL83
CID2733526
Citofen
Crisafeno
D08559
DB00675
Diemon
EINECS 234-118-0
Gen-Tamoxifen
Gen-tamoxifen
HMS1362J11
HMS1792J11
HMS1990J11
HMS2090N08
HSDB 6782
ICI 47699
ICI-46,474
ICI-47699
IDI1_000258
IDI1_002170
Istubol
Kessar
L024126
LS-393
Lopac0_001203
MLS001332535
MLS001332536
MolPort-003-850-384
 
NCGC00024928-01
NCGC00024928-03
NCGC00024928-04
NCGC00024928-05
NCGC00024928-07
NCGC00024928-08
NCGC00024928-09
NCGC00024928-12
NSC727681
Noltam
Nolvadex
Nolvadex-D
Nourytam
Novaldex
Novo-Tamoxifen
Oncomox
PMS-Tamoxifen
Pms-Tamoxifen
Prestwick2_000146
Prestwick3_000146
QTL1_000079
Retaxim
SMR000059172
ST50511785
Spectrum5_001417
Spectrum5_002043
T5648_SIGMA
TAMOXIFEN (TAMOXIFEN CITRATE (54965-24-1))
TRANS FORM OF TAMOXIFEN
Tamizam
Tamofen
Tamone
Tamoplex (TN)
Tamoxasta
Tamoxen
Tamoxifen
Tamoxifen (INN)
Tamoxifen (TN)
Tamoxifen (Z)
Tamoxifen Citrate
Tamoxifen [INN:BAN]
Tamoxifen and its salts
Tamoxifene
Tamoxifene [INN-French]
Tamoxifeno
Tamoxifeno [INN-Spanish]
Tamoxifenum
Tamoxifenum [INN-Latin]
Tamoxifène
Tocris-0999
Tomaxithen
Trans-Tamoxifen
UNII-094ZI81Y45
UPCMLD-DP027
Valodex
Zemide
cMAP_000044
nchembio.140-comp7
nchembio.76-comp1
nchembio732-comp3
tamoxifen
trans-2-[4-(1,2-Diphenyl-1-butenyl)phenoxy]-N,N-dimethylethylamine
trans-Tamoxifen
8
Anastrozoleapproved, investigationalPhase 3, Phase 2279120511-73-12187
Synonyms:
.alpha.,alpha.,.alpha.',.alpha.'-tetramethyl-5(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
1,3-benzenediacetonitrile, a, a, a', a'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)
120511-73-1
2,2'-(5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene)bis(2-methylpropionitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]bis(2-methylpropanenitrile)
2,2'-[5-(1H-1,2,4-triazol-1-ylmethyl)benzene-1,3-diyl]bis(2-methylpropanenitrile)
2-[3-(2-cyanopropan-2-yl)-5-(1,2,4-triazol-1-ylmethyl)phenyl]-2-methylpropanenitrile
AC-4234
AC1L1D49
Anastrazole
Anastrole
Anastrozol
Anastrozole (JAN/USAN/INN)
Anastrozole [USAN:INN:BAN]
Arimidex
Arimidex (TN)
Arimidex (Zeneca)
Arimidex, Anastrozole
Asiolex
Astra brand of anastrozole
AstraZeneca brand of anastrozole
C08159
C090450
C17H19N5
CHEBI:2704
CHEMBL1399
CID2187
CPD000466301
 
D00960
DB01217
HMS2052M11
HMS2089N10
HSDB 7462
I06-0021
ICI D1033
ICI-D 1033
ICI-D1033
LS-29563
MLS000759396
MLS001424217
MolPort-005-933-078
NCGC00164619-01
NSC719344
S1188_Selleck
SAM001246525
SBB066057
SMR000466301
UNII-2Z07MYW1AZ
ZD 1033
ZD-1033
ZD1033
ZINC00000941
Zeneca ZD 1033
Zeneca brand of anastrozole
alpha,alpha,Alpha',alpha'-tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
alpha,alpha,alpha',alpha'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-m-benzenediacetonitrile
anastrazole
anastrozole
9Estrogen Receptor ModulatorsPhase 3, Phase 2645
10Selective Estrogen Receptor ModulatorsPhase 3, Phase 2601
11Bone Density Conservation AgentsPhase 3, Phase 23376
12Antineoplastic Agents, HormonalPhase 3, Phase 25592
13Estrogen AntagonistsPhase 3, Phase 21349
14EstrogensPhase 3, Phase 22542
15Steroid Synthesis InhibitorsPhase 3, Phase 21763
16Aromatase InhibitorsPhase 3, Phase 2826
17
Dutasterideapproved, investigationalPhase 2114164656-23-9152945, 6918296
Synonyms:
(1S,3aS,3bS,5aR,9aR,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
(1S,3aS,3bS,5aR,9aR,9bS,11aS)-N-[2,5-bis(trifluoromethyl)phenyl]-9a,11a-dimethyl-7-oxo-1,2,3,3a,3b,4,5,5a,6,9b,10,11-dodecahydroindeno[5,4-f]quinoline-1-carboxamide
(5.alpha.,17.beta.)-N-{2,5 bis(trifluoromethyl)phenyl}-3-oxo-4-azaandrost-1-ene-17-carboxamide
(5alpha,17beta)-N-(2,5-Bis(trifluoromethyl)phenyl)-3-oxo-4-azaandrost-1-ene-17-carboxamide
164656-23-9
AC1L49EM
AC1OCF98
Avodart
Avodart (TN)
Avodart, Dutasteride
Avolve
Bio-0167
C27H30F6N2O2
CHEBI:132773
CHEMBL1200969
CHEMBL283245
CID152945
CID6918296
CID9914880
D03820
 
DB01126
Duagen
Dutasteride
Dutasteride (JAN/USAN/INN)
Dutasteride [USAN]
FT-0080365
GG 745
GG-745
GI 198745
GI-198745
GI-198745X
LS-173584
MolPort-003-666-660
MolPort-003-847-041
N-[2,5-bis(trifluoromethyl)phenyl]-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxamide
NSC740477
S1202_Selleck
UNII-O0J6XJN02I
ZINC03932831
alpha,alpha,alpha,Alpha',alpha',alpha'-hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide
alpha,alpha,alpha,alpha',alpha',alpha'-Hexafluoro-3-oxo-4-aza-5alpha-androst-1-ene-17beta-carboxy-2',5'-xylidide
18
SpironolactoneapprovedPhase 2, Phase 12321952-01-7, 52-01-75833
Synonyms:
4-18-00-01601 (Beilstein Handbook Reference)
4-Pregnen-21-oic acid-17alpha-ol-3-one-7alpha-thiol gamma-lactone 7-acetate
496916-40-6
52-01-7
7-alpha-Acetylthio-3-oxo-17-alpha-pregn-4-ene-21,17-beta-carbolactone
7alpha-(acetylsulfanyl)-3-oxo-17alpha-pregn-4-ene-21,17-carbolactone
AB00513806
AC-4214
AC1L1L8Q
Abbolactone
Acelat
Aldace
Aldactazide
Aldactide
Aldactone
Aldactone (TN)
Aldactone A
Alderon
Aldopur
Almatol
Alphapharm Brand of Spironolactone
Alpharma Brand of Spironolactone
Alter Brand of Spironolactone
Altex
Aquareduct
Ashbourne Brand of Spironolactone
Azupharma Brand of Spironolactone
BIDD:PXR0071
BPBio1_000194
BRD-K90027355-001-03-4
BRN 0057767
BSPBio_000176
C07310
C24H32O4S
CHEBI:428201
CHEBI:45692
CHEBI:9241
CHEMBL1393
CID5833
CPD000471892
Cardel Brand of Spironolactone
D00443
D013148
DB00421
Deverol
Dexo Brand of Spironolactone
Diatensec
Dira
Duraspiron
EINECS 200-133-6
Espironolactona
Espironolactona Alter
Espironolactona Mundogen
Espironolactona [INN-Spanish]
Euteberol
Flumach
Frumikal
Generosan Brand of Spironolactone
HMS1568I18
HMS2090N21
HSDB 3184
Hormosan Brand of Spironolactone
I06-1970
Jenapharm Brand of Spironolactone
Jenaspiron
LS-118614
LT00772287
Lacalmin
Lacdene
Laractone
MLS001074672
MLS001333253
MLS001333254
MLS002153245
MLS002207058
Mayoly-Spindler Brand of Spironolactone
Melarcon
Merck dura Brand of Spironolactone
Mundogen Brand of Spironolactone
NCGC00164397-01
 
NCGC00164397-02
NSC 150399
NSC150399
Nefurofan
Novo Spiroton
Novo-Spiroton
NovoSpiroton
Novopharm Brand of Spironolactone
Osyrol
Pfizer Brand of Spironolactone
Pharmafrid Brand of Spironolactone
Practon
Prestwick0_000128
Prestwick1_000128
Prestwick2_000128
Prestwick3_000128
Roche Brand of Spironolactone
S0260
S3378_SIGMA
SAM002264648
SC 9420
SC-9420
SC9420
SMR000471892
SNL
SPBio_002115
Sagisal
Searle Brand of Spironolactone
Sincomen
Spiractin
Spiresis
Spiretic
Spiridon
Spiro L.U.T.
Spiro(17H-cyclopenta(a)phenauthrene-17,2'-(3'H)-furan)
Spiro-Tablinen
Spiro[17H-cyclopenta[a]phenauthrene-17,2'-(3'H)-furan]
Spirobeta
Spiroctan
Spiroctanie
Spiroderm
Spirogamma
Spirolactone
Spirolakton
Spirolang
Spirolone
Spirone
Spirono Isis
Spirono-Isis
Spironocompren
Spironolactone
Spironolactone (JP15/USP/INN)
Spironolactone A
Spironolactone [BAN:INN:JAN]
Spironolactone [INN:BAN:JAN]
Spironolactonum
Spironolactonum [INN-Latin]
Spironolattone
Spironolattone [DCIT]
Spironone
Spirospare
Sprioderm
Supra-puren
Suracton
UNII-27O7W4T232
Uractone
Urusonin
Veroshpiron
Verospiron
Verospirone
Verospirone Opianin
WLN: L E5 B666 FX OV MUTJ A1 E1 KSV1 F-& CT5VOXTJ
Worwag Brand of Spironolactone
Xenalon
ZINC03861599
betapharm Brand of Spironolactone
ct Arzneimittel Brand of Spironolactone
ct-Arzneimittel Brand of Spironolactone
spiro von ct
spironolactone
spironolattone
von ct, spiro
19
Testosteroneapproved, investigationalPhase 256358-22-06013
Synonyms:
(+)-testosterone
(+-)-8-iso-testosterone
(+-)-retrotestosterone
(+-)-testosterone
(17b)-17-hydroxy-androst-4-en-3-one
(17beta)-17-Hydroxyandrost-4-en-3-one
(8R,9S,10R,13S,14S,17S)-17-hydroxy-10,13-dimethyl-1,2,6,7,8,9,11,12,14,15,16,17-dodecahydrocyclopenta[a]phenanthren-3-one
13-Iso-testosterone
17-Hydroxy-(17-beta)-androst-4-en-3-one
17-Hydroxy-(17beta)-androst-4-en-3-one
17-Hydroxy-10,13-dimethyl-1,2,6,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-cyclopenta[a]phenanthren-3-one
17-Hydroxy-D4-androsten-3-one
17-Hydroxy-androst-4-en-3-one
17-beta-Hydroxy-delta(sup 4)-androsten-3-one
17-beta-Hydroxyandrost-4-en-3-one
17?-Hydroxy-4-androsten-3-one
17a-Hydroxy-(13a)-androst-4-en-3-one
17a-Hydroxy-13a-androst-4-en-3-one
17a-Hydroxy-14b-androst-4-en-3-one
17a-Hydroxy-androst-4-en-3-one
17b-Hydroxy-(10a)-androst-4-en-3-one
17b-Hydroxy-(13a)-androst-4-en-3-one
17b-Hydroxy-(8a)-androst-4-en-3-one
17b-Hydroxy-(8a,10a)-androst-4-en-3-one
17b-Hydroxy-(9b)-androst-4-en-3-one
17b-Hydroxy-(9b,10a)-androst-4-en-3-one
17b-Hydroxy-13a-androst-4-en-3-one
17b-Hydroxy-8a-androst-4-en-3-one
17b-Hydroxy-D4-androsten-3-one
17b-Hydroxy-androst-4-en-3-on
17b-Hydroxy-androst-4-en-3-one
17b-Hydroxyandrost-4-en-3-one
17b-Hydroxyandrost-4-ene-3-one
17b-Testosterone
17b-hydroxy-4-androsten-3-one
17beta-Hydroxy-3-oxo-4-androstene
17beta-Hydroxy-4-androsten-3-one
17beta-Hydroxy-delta(sup4)-androsten-3-one
17beta-Hydroxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-ene-3-one
17beta-hydroxy-4-androsten-3-one
4-Androsten-17?-ol-3-one
4-Androsten-17beta-ol-3-one
4-Androsten-3-one-17b-ol
4-androsten-17β-ol-3-one
4-androstene-17beta-ol-3-one
46923_FLUKA
46923_RIEDEL
58-22-0
7-beta-Hydroxyandrost-4-en-3-one
8-Iso-testosterone
9b,10a-Testosterone
9b-Testosterone
AA 2500
AC-14899
AC1L1LM0
Andriol
Andro
Andro 100
Andro L.A. 200
AndroGel
Androderm
Androderm (TN)
Androgel
Androgel (TN)
Android 10
Android 25
Android 5
Androlin
Andronaq
Andronate 100
Andronate 200
Andropatch
Andropository 200
Androsorb
Androst-4-en-17b-ol-3-one
Androst-4-en-17beta-ol-3-one
Androst-4-ene-17b-ol-3-one
Andrusol
Andryl 200
B5DEE83F-632B-48A1-A0ED-A51E7F13DF2E
BIDD:ER0555
BIM-0061761.0001
Beta Testosterone
Bio-0678
Bio-T-Gel
C00535
CCRIS 574
CDB 111C
CHEBI:17347
CHEMBL386630
CID6013
CMC_13449
COL 1621
CP 601B
CPD000058344
Cristerona T
Cristerone T
D00075
D4-Androsten-17b-ol-3-one
DB00624
Dea No. 4000
Delatest
Delatestryl
Depo-Testadiol
Depo-Testosterone
Depo-Testosterone Cypionate
Depotest
EINECS 200-370-5
Epitestosteron
Everone 200
Geno-Cristaux Gremy
Geno-cristaux Gremy
Geno-cristaux gremy
HMS2052N11
HSDB 3398
Halotensin
Homosteron
Homosterone
 
Intrinsa
LMST02020002
LS-148813
LibiGel
Libigel
Lumitestosteron
MLS000563091
MLS001032098
MLS001306401
MLS002174283
Malerone
Malestrone
Malestrone (amps)
Malogen in Oil
Malogen, Aquaspension Injection
Malogen, aquaspension injection
Mertestate
Metandren
Methyltestosterone
MolPort-002-506-901
NCGC00091018-01
NSC 9700
Neo-Hombreol F
Neo-Testis
Neo-testis
Neotestis
Oreton
Oreton F
Oreton Methyl
Oreton-F
Orquisteron
Perandren
Percutacrine Androgenique
Percutacrine androgenique
Primotest
Primoteston
Rac-17b-hydroxy-(13a)androst-4-en-3-one
Rac-17b-hydroxy-(8a)-androst-4-en-3-one
Rac-17b-hydroxy-(9b,10a)androst-4-en-3-one
Rac-17b-hydroxy-androst-4-en-3-one
Relibra
Retrotestosterone
S00309
S2033_Selleck
SAM001246921
SMR000058344
SMR001261453
Scheinpharm Testone-Cyp
Striant
Striant (TN)
Sustanon
Sustanone
Sustason 250
Synandrol F
T-Cypionate
T1500_SIGMA
T5411_FLUKA
T5411_SIGMA
TES
Teslen
Testamone 100
Testandrone
Testaqua
Testiculosterone
Testim
Testim (TN)
Testobase
Testoderm
Testoderm Tts
Testogel
Testoject-50
Testolent
Testolin
Testopel Pellets
Testopropon
Testosteroid
Testosteron
Testosterona
Testosterona [INN-Spanish]
Testosterone
Testosterone (JAN/USP)
Testosterone Cypionate
Testosterone Enanthate
Testosterone Hydrate
Testosterone [Androgenic steroids, anabolic]
Testosterone [INN:BAN]
Testosterone and its esters
Testosterone hydrate
Testosterone solution
Testosteronum
Testosteronum [INN-Latin]
Testostosterone
Testostérone
Testoviron
Testoviron Schering
Testoviron T
Testoxyl
Testred
Testred Cypionate 200
Testrin-P.A
Testro AQ
Testro Aq
Testrone
Testryl
Tostrelle
Tostrex
Trans-Testosterone
UNII-3XMK78S47O
Viatrel
Virilon
Virilon IM
Virormone
Virosterone
ZINC06500184
beta testosterone
delta(sup 4)-Androsten-17(beta)-ol-3-one
delta4-Androsten-17beta-ol-3-one
delta4-androsten-17b-ol-3-one
testosterone
trans-Testosterone
20
MethyltestosteroneapprovedPhase 256358-18-46010
Synonyms:
17(alpha)-Methyl-delta(4)-androsten-17(beta)-ol-3-one
17-Methyltestosterone
17-beta-Hydroxy-17-methylandrost-4-en-3-one
17-methyltestosterone
17alpha-Methyl-3-oxo-4-androsten-17beta-ol
17alpha-Methyl-delta(4)-androsten-17beta-ol-3-one
17alpha-Methyltestosterone
17alpha-methyl-delta-androsten-17beta-ol-3-one
17alpha-methyltestosterone
 
17beta-Hydroxy-17-methylandrost-4-en-3-one
17α-methyl-Δ4-androsten-17β-ol-3-one
17α-methyltestosterone
4-Androstene-17alpha-methyl-17beta-ol-3-one
Android
Methyltestosterone
Methyltestosteronum
Metiltestosterona
NSC-9701
Testred
Virilon
21
TestolactoneapprovedPhase 24968-93-413769
Synonyms:
(4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-3,4,4a,5,6,10a,10b,11,12,12a-decahydro-2H-naphtho[2,1-f]chromene-2,8(4bH)-dione
(4aS,4bR,10aR,10bS,12aS)-10a,12a-dimethyl-4,4a,4b,5,6,10b,11,12-octahydro-3H-naphtho[2,1-f]chromene-2,8-dione
.DELTA.1-Dehydrotestolactone
.DELTA.1-Dehydrotestololactone
.DELTA.1-Testololactone
1 Dehydrotestolactone
1,2,3,4,4a,4b,7,9,10,10a-Decahydro-2-hydroxy-2,4b-dimethyl-7-oxo-1-phenanthrenepropionic acid delta-lactone
1,2-Dehydrotestololactone
1,2-didehydrotestololactone
1-Dehydrotestolactone
1-dehydrotestololactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, .delta.-lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, delta-lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, delta-lactone (8CI)
13,17-Secoandrosta-1,4-dien-17-oic acid, 13-hydroxy-3-oxo-, lactone
13,17-Secoandrosta-1,4-dien-17-oic acid, 13.alpha.-hydroxy-3-oxo-, .delta.-lactone
13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid .delta.-lactone
13-Hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid delta-lactone
13-hydroxy-3-oxo-13,17-secoandrosta-1,4-dien-17-oic acid δ-lactone
17a-Oxa-D-homoandrosta-1,4-diene-3,17-dione
17alpha-Oxo-D-homo-1,4-androstadiene-3,17-dione
2H-Phenanthro[2,1-b]pyran-2,8(4bH)-dione, 3,4,4a,5,6,10a,10b,11,12,12a-decahydro-10a,12a-dimethyl-, lactone
3-oxo-13,17-secoandrosta-1,4-dieno-17,13alpha-lactone
968-93-4
AC1L22FS
Bristol Myers Squibb Brand of Testolactone
Bristol-Myers Squibb Brand of Testolactone
C02197
C19H24O3
CHEBI:9460
CHEMBL1571
CID13769
D-Homo-17A-oxaandrosta-1,4-diene-3,17-dione
D-homo-17a-oxaandrosta-1,4-diene-3,17-dione
D00153
 
D013738
DB00894
Delta(1)-testololactone
Delta-1-testololactone
EINECS 213-534-6
Fludestrin
HSDB 3255
LMST02020084
LS-102968
MolPort-004-286-011
NCI60_001908
NSC 23759
NSC-12173
NSC23759
SQ 9538
SQ-9538
TESLAC (TN)
Teolit
Teslac
Teslak
Testolacton
Testolactona
Testolactona [INN-Spanish]
Testolactone
Testolactone (USP/INN)
Testolactone [USAN:INN]
Testolactonum
Testolactonum [INN-Latin]
Testolattone
Testolattone [DCIT]
Testolattone [Dcit]
UNII-6J9BLA949Q
ZINC04081771
delta(1)-Dehydrotestolactone
delta(1)-Testolactone
delta(1)-testololactone
Δ1-testololactone
225-alpha Reductase InhibitorsPhase 2167
23DeslorelinPhase 2176
24Diuretics, Potassium SparingPhase 2, Phase 11917
25
Testosterone enanthatePhase 2563315-37-79416
Synonyms:
17-((1-Oxoheptyl)oxy)androst-4-en-3-one
17-Hydroxyandrost-4-en-3-one, 17-heptanoate
17-Hydroxyandrost-4-en-3-one, 17-heptanoic acid
17beta-Enanthoxyandrost-4-en-3-one
17beta-Hydroxyandrost-4-en-3-one enanthate
4-Androsten-17beta-ol-3-one 17-enanthate
4-Androsten-3-one 17beta-enanthate
Androgyn L.A.
Andropository
Androtardyl
Atlatest
DEA No. 4000
DePatestrye
Delatest
Delatestryl
Depo-Testro Med
Ditate
Durathate
Everone
 
Exten test
Malogen L.A.
Malogen L.A.200
Orquisteron-E
Primotestone
Reposo TMD
Testanthate
Testate
Testenate
Testinon
Testoenant
Testonenant
Testosterone 17-enanthate
Testosterone 17beta-heptanoate
Testosterone 17beta-heptanoic acid
Testosterone enantate
Testosterone heptoate
Testosterone heptoic acid
Testosterone heptylate
Testosterone oenanthate
Testostroval
26Testosterone undecanoatePhase 2563
27Testosterone 17 beta-cypionatePhase 2563
28diureticsPhase 2, Phase 11418
29Mineralocorticoid Receptor AntagonistsPhase 2, Phase 1346
30MineralocorticoidsPhase 2, Phase 1367
31Natriuretic AgentsPhase 2, Phase 11697
32Tranquilizing Agents4265
33Quetiapine Fumarate413111974-72-2
34Antipsychotic Agents2401
35Central Nervous System Depressants13403
36Psychotropic Drugs6430

Interventional clinical trials:

(show all 14)
idNameStatusNCT IDPhase
1Compare the Value of Prophylactic Versus Therapeutic Breast Radiotherapy in CASODEXCompletedNCT00590213Phase 4
2Gynecomastia Extension StudyCompletedNCT00637182Phase 3
3Two Different Regimens of Nolvadex in Preventing Gynecomastia Induced by Casodex 150 mg in Patients With Prostate CancerCompletedNCT00233610Phase 3
4Efficacy and Toxicity of Bicalutamide and Dutasteride vs. Standard Care for Prostate Cytoreduction for BrachytherapyUnknown statusNCT00866554Phase 2
5Open Label Arimidex in GynecomastiaCompletedNCT00241436Phase 2
6Casodex - Nolvadex CombinationCompletedNCT00637871Phase 2
7Treatment of Boys With Precocious PubertyCompletedNCT00001202Phase 2
8Spironolactone for Pulmonary Arterial HypertensionRecruitingNCT01712620Phase 1, Phase 2
9Eplerenone Versus Spironolactone as Treatment of Ascites Due to Liver Cirrhosis; a Study of Efficacy and Side EffectsWithdrawnNCT01801228Phase 2
10Targeted Fat Reduction of Pseudogynecomastia in the Male Breast Using the ZELTIQ Coolsculpting SystemUnknown statusNCT01791660
11Changes in Hyperprolactinemia Secondary to Antipsychotics After Switching to QuetiapineCompletedNCT00952757
12Adaptation Among Adolescents and Adults With Klinefelter SyndromeCompletedNCT00896272
13Sperm Production in Kleinfelter Syndrome Patients After Mesenchymal Stem Cell InjectionCompletedNCT02414295
14UltraShape Device for Non-Invasive Fat Reduction in the Male Breast (Pseudogynecomastia)RecruitingNCT02711605

Search NIH Clinical Center for Gynecomastia

Inferred drug relations via UMLS68/NDF-RT46:

Genetic Tests for Gynecomastia

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Genetic tests related to Gynecomastia:

id Genetic test Affiliating Genes
1 Gynecomastia27

Anatomical Context for Gynecomastia

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MalaCards organs/tissues related to Gynecomastia:

36
Breast, Prostate, Skin, Lung, Testis, Liver, Spinal cord

Publications for Gynecomastia

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Articles related to Gynecomastia:

(show top 50)    (show all 627)
idTitleAuthorsYear
1
Spironolactone-induced bilateral gynecomastia in a man detected by SPECT myocardial perfusion imaging. (27151301)
2016
2
Gynecomastia With Atypical Ductal Hyperplasia and Ductal Carcinoma In Situ Associated With Invasive Breast Carcinoma in a Male Patient on Antiretroviral Therapy: A Case Report. (26612847)
2016
3
Incremental Role of Mammography in the Evaluation of Gynecomastia in Men Who Have Undergone Chest CT. (27101347)
2016
4
Bilateral Atypical Ductal Hyperplasia with Microcalcifications in a Patient with Gynecomastia. (27218035)
2016
5
Sexual function and hormone profile in young adult men with idiopathic gynecomastia: Comparison with healthy controls. (27177337)
2016
6
Surgical management of gynecomastia: experience of a general surgery center. (27938530)
2016
7
Endocrine and molecular investigations in a cohort of 25 adolescent males with prominent/persistent pubertal gynecomastia. (26845730)
2016
8
Gynecomastia in the Ancient Egypt limestone statue of Hemiunu, the architect of the Great Pyramid of Giza (fl. 2570 BC). (27761884)
2016
9
Gynecomastia Management: An Evolution and Refinement in Technique at UT Southwestern Medical Center. (27482482)
2016
10
Gynecomastia and Hyperprolactinemia Secondary to Advanced Allergic Fungal Rhinosinusitis in a Pediatric Patient. (26768883)
2016
11
Gynecomastia: a common indication for mammography in men of all age. (27467870)
2016
12
Radiation therapy for primary breast lymphoma in male gynecomastia: a rare case report and review of the literature. (27225235)
2016
13
Incidental unilateral and bilateral ductal carcinoma in situ encountered in the surgical management of young male gynecomastia. (27612041)
2016
14
Breast US as primary imaging modality for diagnosing gynecomastia. (27734795)
2016
15
Gynecomastia as a Paraneoplastic Symptom of Choriocarcinoma. (27629979)
2016
16
Association between plasma kisspeptin levels and adolescent gynecomastia. (27502882)
2016
17
Multiple Schwannomas in a Patient with Gynecomastia. (27988983)
2016
18
Anatomy of the Gynecomastia Tissue and Its Clinical Significance. (27622122)
2016
19
Johnson & Johnson is ordered to pay $70m to boy who developed gynecomastia. (27402539)
2016
20
Combined approach for gynecomastia. (26955509)
2016
21
Inherited Xq13.2-q21.31 duplication in a boy with recurrent seizures and pubertal gynecomastia: Clinical, chromosomal and aCGH characterization. (27617217)
2016
22
Gynecomastia and hormones. (27145756)
2016
23
Orange Peel Excision of Gland: A Novel Surgical Technique for Treatment of Gynecomastia. (26999715)
2016
24
Evaluation of Serum Vitamin D Levels in Adolescents with Pubertal Gynecomastia. (27920626)
2016
25
Surgical Management of Gynecomastia: Subcutaneous Mastectomy and Liposuction. (27679453)
2016
26
A Novel Mutation In Human Androgen Receptor Gene Causing Partial Androgen Insensitivity Syndrome In A Patient Presenting With Gynecomastia At Puberty. (27087292)
2016
27
RESPONSE TO THE ANASTROZOLE TREATMENT IN A CASE WITH PEUTZ-JEGHERS SYNDROME WHO WAS DETECTED TO HAVE LARGE CELL CALCIFYING SERTOLI CELL TUMOR AND DEVELOPED PRE-PUBERTAL GYNECOMASTIA. (27873740)
2016
28
Intratubular large cell hyalinizing Sertoli cell tumor of the testis presenting with prepubertal gynecomastia: a case report. (27488929)
2016
29
No-Drain Single Incision Liposuction Pull-Through Technique for Gynecomastia. (28032170)
2016
30
Prepubertal Gynecomastia Due to Indirect Exposure to Nonformulary Bioidentical Hormonal Replacement Therapy: A Case Report. (26995893)
2016
31
Gynecomastia Surgery-Impact on Life Quality: A Prospective Case-Control Study. (27404477)
2016
32
The Satisfaction Rate among Patients and Surgeons after Periareolar Surgical Approach to Gynecomastia along with Liposuction. (27853693)
2016
33
Case 32-2016. A 20-Year-Old Man with Gynecomastia. (27797319)
2016
34
Who Gets Severe Gynecomastia Among HIV-Infected Children In The UK And Ireland? (27879556)
2016
35
Management of Gynecomastia in Patients With Different Body Types: Considerations on 312 Consecutive Treated Cases. (27805927)
2016
36
Surgical Strategies in the Treatment of Gynecomastia Grade I-II: The Combination of Liposuction and Subcutaneous Mastectomy Provides Excellent Patient Outcome and Satisfaction. (26557823)
2015
37
The effect of tamoxifen on pubertal bone development in adolescents with pubertal gynecomastia. (26353169)
2015
38
Large pseudoangiomatous stromal hyperplasia complicated with gynecomastia and lobular differentiation in a male breast. (26101734)
2015
39
Pseudoangiomatous stromal hyperplasia with multinucleated stromal giant cells is neither exceptional in gynecomastia nor characteristic of neurofibromatosis type 1. (25586494)
2015
40
The role of Ad-36 as a risk factor in males with gynecomastia. (26394544)
2015
41
Laser-Assisted Liposuction Using the Novel 1,444-nm Nd:YAG Laser for the Treatment of Gynecomastia: A Pilot Study. (26183712)
2015
42
A Rare Cause of Prepubertal Gynecomastia: Sertoli Cell Tumor. (26366315)
2015
43
Gynecomastia induced by H1-antihistamine (ebastine) in a patient with idiopathic anaphylaxis. (26240797)
2015
44
Gynecomastia and Klinefelter Syndrome. (26715949)
2015
45
Primary cutaneous apocrine gland carcinoma from areolar tissue in a male patient with gynecomastia: a case report. (26349536)
2015
46
Mixed gynecomastia. (26318471)
2015
47
Gynecomastia in Patients with Prostate Cancer: A Systematic Review. (26308532)
2015
48
Can digit ratio (2D:4D) studies be helpful in explaining the aetiology of idiopathic gynecomastia? (25543532)
2015
49
GPR30 Gene Polymorphisms Are Associated with Gynecomastia Risk in Adolescents. (25531203)
2015
50
The effect of gynecomastia on body image perception and gender roles in adolescents. (26613222)
2015

Variations for Gynecomastia

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Expression for genes affiliated with Gynecomastia

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Search GEO for disease gene expression data for Gynecomastia.

Pathways for genes affiliated with Gynecomastia

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GO Terms for genes affiliated with Gynecomastia

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Biological processes related to Gynecomastia according to GeneCards Suite gene sharing:

(show all 13)
idNameGO IDScoreTop Affiliating Genes
1androgen metabolic processGO:000820910.5CYP19A1, ESR1
2testosterone biosynthetic processGO:006137010.5CYP19A1, HSD17B3
3peptide hormone processingGO:001648610.1CGA, POMC
4prostate gland growthGO:006073610.1AR, CYP19A1
5mammary gland alveolus developmentGO:006074910.0AR, ESR1
6sex differentiationGO:00075489.9AR, SRY
7uterus developmentGO:00600659.8CYP19A1, ESR1
8tertiary branching involved in mammary gland duct morphogenesisGO:00607489.8AR, PGR
9steroid hormone mediated signaling pathwayGO:00434019.4AR, ESR1, PGR
10transcription initiation from RNA polymerase II promoterGO:00063679.1AR, ESR1, PGR
11regulation of transcription from RNA polymerase II promoterGO:00063579.0AR, CGA, ESR1, SRY
12cell-cell signalingGO:00072678.8AR, CGA, PGR, POMC
13positive regulation of transcription from RNA polymerase II promoterGO:00459448.3AR, CGA, ESR1, PGR, POMC

Molecular functions related to Gynecomastia according to GeneCards Suite gene sharing:

(show all 8)
idNameGO IDScoreTop Affiliating Genes
1androgen bindingGO:000549710.0AR, SHBG
2hormone activityGO:00051799.7CGA, POMC, PRL
3ATPase bindingGO:00511179.5AR, ESR1, PGR
4RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA bindingGO:00048799.3AR, ESR1, PGR
5lipid bindingGO:00082899.0AR, ESR1, PGR, SHBG
6enzyme bindingGO:00198998.9AR, ESR1, PGR, PHF6
7steroid bindingGO:00054968.9AR, ESR1, PGR, SHBG
8steroid hormone receptor activityGO:00037078.8AR, ESR1, PGR

Sources for Gynecomastia

About this section
2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
27GTR
28HGMD
29HMDB
30ICD10
31ICD10 via Orphanet
32ICD9CM
33IUPHAR
34KEGG
37MedGen
39MeSH
40MESH via Orphanet
41MGI
44NCI
45NCIt
46NDF-RT
49NINDS
50Novoseek
52OMIM
53OMIM via Orphanet
57PubMed
58QIAGEN
63SNOMED-CT via Orphanet
67Tumor Gene Family of Databases
68UMLS
69UMLS via Orphanet