MCID: HMP009
MIFTS: 41

Haemophilus Influenzae malady

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Summaries for Haemophilus Influenzae

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Wikipedia:65 Haemophilus influenzae (formerly called Pfeiffer\'s bacillus or Bacillus influenzae) is a Gram-negative,... more...

MalaCards based summary: Haemophilus Influenzae, also known as h. influenzae, is related to meningitis and pneumonia. An important gene associated with Haemophilus Influenzae is OMP (olfactory marker protein), and among its related pathways are NF-kappaB Signaling and Phagocytosis of Microbes. The compounds bifidobacterium and hbd2 have been mentioned in the context of this disorder. Affiliated tissues include colon, lung and tonsil.

Aliases & Classifications for Haemophilus Influenzae

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Related Diseases for Haemophilus Influenzae

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Graphical network of the top 20 diseases related to Haemophilus Influenzae:



Diseases related to haemophilus influenzae

Symptoms for Haemophilus Influenzae

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Drugs & Therapeutics for Haemophilus Influenzae

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Drug clinical trials:

Search ClinicalTrials for Haemophilus Influenzae

Search NIH Clinical Center for Haemophilus Influenzae

Genetic Tests for Haemophilus Influenzae

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Anatomical Context for Haemophilus Influenzae

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MalaCards organs/tissues related to Haemophilus Influenzae:

32
Colon, Lung, Tonsil, Monocytes, Bone, Prostate, Testes, B cells, Neutrophil

Animal Models for Haemophilus Influenzae or affiliated genes

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Publications for Haemophilus Influenzae

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Articles related to Haemophilus Influenzae:

(show top 50)    (show all 442)
idTitleAuthorsYear
1
Haemophilus haemolyticus is infrequently misidentified as Haemophilus influenzae in diagnostic specimens in Australia. (25266675)
2014
2
Peroxiredoxin/glutaredoxin (pdgX) and catalase (htkE) promote resistance of nontypeable Haemophilus influenzae 86-028NP to oxidant and survival within neutrophil extracellular traps. (25348637)
2014
3
Haemophilus influenzae oral vaccination for preventing acute exacerbations of chronic bronchitis and chronic obstructive pulmonary disease. (25201571)
2014
4
Calcium Restores the Macrophage Response to Non-typeable Haemophilus influenzae in COPD. (25338285)
2014
5
Three-year antibody persistence and safety after a single dose of combined haemophilus influenzae type b (Hib)-Neisseria meningitidis serogroup C-tetanus toxoid conjugate vaccine in Hib-primed toddlers. (23080288)
2013
6
Complete Genome Sequence of Encapsulated Haemophilus influenzae Type f KR494, an Invasive Isolate That Caused Necrotizing Myositis. (24092777)
2013
7
In vitro chloramphenicol detection in a Haemophilus influenza model using an aptamer-polymer based electrochemical biosensor. (24412768)
2013
8
Randomized, controlled, multicenter study of the immunogenicity and safety of a fully liquid combination diphtheria-tetanus toxoid-five-component acellular pertussis (DTaP5), inactivated poliovirus (IPV), and haemophilus influenzae type b (Hib) vaccine compared with a DTaP3-IPV/Hib vaccine administered at 3, 5, and 12 months of age. (23966556)
2013
9
Haemophilus influenzae type f meningitis in a previously healthy boy. (23645639)
2013
10
Kinetic analysis and evaluation of the mechanisms involved in the resolution of experimental nontypeable Haemophilus influenzae-induced otitis media after transcutaneous immunization. (23092856)
2013
11
Improvement rate of acute otitis media caused by Haemophilus influenzae at 1 week is significantly associated with time to recovery. (23966504)
2013
12
Antiinflammatory role of MUC1 mucin during infection with nontypeable Haemophilus influenzae. (22298528)
2012
13
A functional tonB gene is required for both virulence and competitive fitness in a chinchilla model of Haemophilus influenzae otitis media. (22731867)
2012
14
Modified lipooligosaccharide structure protects nontypeable Haemophilus influenzae from IgM-mediated complement killing in experimental otitis media. (22761391)
2012
15
Non-capsulated and capsulated Haemophilus influenzae in children with acute otitis media in Venezuela: a prospective epidemiological study. (22335965)
2012
16
Experimental design to optimize an Haemophilus influenzae type b conjugate vaccine made with hydrazide-derivatized tetanus toxoid. (21850577)
2011
17
Haemophilus influenzae protein E recognizes the C-terminal domain of vitronectin and modulates the membrane attack complex. (21542857)
2011
18
Safety and immunogenicity of three different formulations of a liquid hexavalent diphtheria-tetanus-acellular pertussis-inactivated poliovirus-Haemophilus influenzae b conjugate-hepatitis B vaccine at 2, 4, 6 and 12-14 months of age. (21134456)
2011
19
Haemophilus influenzae type b-Neisseria meningitidis serogroups C and Y tetanus toxoid conjugate vaccine for infants and toddlers. (21806393)
2011
20
Primary and booster immunization with a diphtheria, tetanus, acellular pertussis, hepatitis B (DTPa-HBV) and Haemophilus influenzae type b (Hib) vaccine administered separately or together is safe and immunogenic. (19467896)
2010
21
Toll-like receptor 3 is involved in airway epithelial cell response to nontypeable Haemophilus influenzae. (19878930)
2010
22
Phenotypic and molecular characterization of beta-lactam resistance and capsular typing of colonizing Haemophilus influenzae strains isolated from neutropenic patients in Tunisia. (18178031)
2009
23
Nontypeable Haemophilus influenzae clearance by alveolar macrophages is impaired by exposure to cigarette smoke. (19620348)
2009
24
Immunogenicity and reactogenicity of two diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated polio virus-Haemophilus influenzae type b vaccines administered at 3, 5 and 11-12 months of age. (18690013)
2009
25
Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB). (19588375)
2009
26
The role of p38 mitogen activated protein kinase in the inflammatory response of human monocytes infected with nontypeable Haemophilus influenzae]. (18953958)
2008
27
The immunological response of Thai infants to haemophilus influenzae type B polysaccharide-tetanus conjugate vaccine co-administered in the same syringe with locally produced diphtheria-tetanus-pertussis vaccine. (17710973)
2007
28
Characterization of genetic and phenotypic diversity of invasive nontypeable Haemophilus influenzae. (16113304)
2005
29
Epiglottitis in Sydney before and after the introduction of vaccination against Haemophilus influenzae type b disease. (16105154)
2005
30
Dynamics of long-term colonization of respiratory tract by Haemophilus influenzae in cystic fibrosis patients shows a marked increase in hypermutable strains. (15070988)
2004
31
The tetrameric structure of Haemophilus influenza hybrid Prx5 reveals interactions between electron donor and acceptor proteins. (12529327)
2003
32
Outer-membrane-protein subtypes of Haemophilus influenzae isolates from North India. (12867564)
2003
33
Apparent plateau in beta-lactamase production among clinical isolates of Haemophilus influenzae and Moraxella catarrhalis in the United States: results from the LIBRA Surveillance initiative. (11850164)
2002
34
Interaction of vitronectin with Haemophilus influenzae. (12423774)
2002
35
Properties of recombinant HtrA: an otitis media vaccine candidate antigen from non-typeable Haemophilus influenzae. (11214237)
2000
36
Anti-CD14 monoclonal antibodies inhibit the production of tumor necrosis factor alpha and interleukin-10 by human monocytes stimulated with killed and live Haemophilus influenzae or Streptococcus pneumoniae organisms. (10417128)
1999
37
Study on serotyping of Haemophilus influenzae and the positive rates of beta-lactamase]. (11776776)
1999
38
Haemophilus influenzae and Streptococcus pyogenes group A challenge induce a Th1 type of cytokine response in cells obtained from tonsillar hypertrophy and recurrent tonsillitis. (9519380)
1998
39
Epiglottitis and Haemophilus influenzae immunization: the Pittsburgh experience--a five-year review. (7651772)
1995
40
In vitro effect of dexamethasone, pentoxifylline, and anti-endotoxin monoclonal antibody on the release of proinflammatory mediators by human leukocytes stimulated with Haemophilus influenzae type B. (7936825)
1994
41
Haemophilus influenzae type D infection and IgG2 deficiency in a patient with chronic mucocutaneous candidiasis. (8203272)
1994
42
In vitro activation of human T lymphocytes by Haemophilus influenzae type b capsular polysaccharides. (1346727)
1992
43
Environmental chemoprevention of Haemophilus influenzae type B meningitis. Consequences of 2 indirectly related case pairs]. (1640949)
1992
44
Isolation of an outer membrane hemin-binding protein of Haemophilus influenzae type b. (1541554)
1992
45
Purulent salpingitis and intra-uterine contraceptive device-related infection due to Haemophilus influenzae. (2002228)
1991
46
Differences in subtype distribution of Haemophilus influenzae type b from carriers in the general population and patients with meningitis. (2056515)
1991
47
Haemophilus influenzae type B: subtyping of strains isolated from respiratory infections using the outer membrane protein profiles]. (2102010)
1990
48
Ataxia and hypotonia in Haemophilus influenzae type b meningitis. (3257821)
1988
49
Radiological case of the month. Bronchogenic cyst infected with Haemophilus influenzae. (3258731)
1988
50
Haemophilus influenza type b orbital cellulitis. (6057129)
1967

Variations for Haemophilus Influenzae

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Expression for genes affiliated with Haemophilus Influenzae

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Expression patterns in normal tissues for genes affiliated with Haemophilus Influenzae

Search GEO for disease gene expression data for Haemophilus Influenzae.

Pathways for genes affiliated with Haemophilus Influenzae

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Pathways related to Haemophilus Influenzae according to GeneCards/GeneDecks:

idSuper pathways (with members indented)ScoreTop Affiliating Genes
19.5CLEC7A, TLR2
29.5VTN, TLR2
3
Show member pathways
9.4TLR2, DEFB4A
4
Show member pathways
Transcription NF kB signaling pathway60
Immune response Toll like receptor TLR ligands and common TLR signaling pathway leading to cell proinflammatory response60
9.4TLR2, DEFB4A

Compounds for genes affiliated with Haemophilus Influenzae

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Compounds related to Haemophilus Influenzae according to GeneCards/GeneDecks:

(show all 17)
idCompoundScoreTop Affiliating Genes
1bifidobacterium449.8TDO2, TLR2
2hbd2449.7DEFB4A, TLR2
3zymosan449.7CLEC7A, TLR2
4hcec449.7TLR2, DEFB4A
5lipoteichoic acid449.6TLR2, DEFB4A
6carbon449.5VTN, GALE, TDO2
7flagellin44 2810.5OMP, TLR2, DEFB4A
8peptidoglycan44 2810.4OMP, TLR2, DEFB4A
9sp 60012544 6110.4TLR2, DEFB4A
10mannose449.4CLEC7A, TLR2, DEFB4A
11anti-fungal449.3DEFB4A, TLR2
12latex449.2VTN, TLR2
13pd 98,059449.1DEFB4A, TLR2, VTN
14polysaccharide449.0TLR2, OMP, VTN, GALE
15dexamethasone44 50 28 1112.0DEFB4A, TLR2, CLEC7A, VTN
16tyrosine448.6DEFB4A, TLR2, CLEC7A, VTN, TDO2
17cysteine448.6ROM1, VTN, TLR2, DEFB4A

GO Terms for genes affiliated with Haemophilus Influenzae

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Biological processes related to Haemophilus Influenzae according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1cell surface pattern recognition receptor signaling pathwayGO:0027529.5CLEC7A, TLR2
2positive regulation of tumor necrosis factor productionGO:0327609.2CLEC7A, TLR2
3immune responseGO:0069559.1VTN, TLR2, DEFB4A
4innate immune responseGO:0450878.6DEFB4A, TLR2, CLEC7A, VTN

Molecular functions related to Haemophilus Influenzae according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1signaling pattern recognition receptor activityGO:0083299.5CLEC7A, TLR2

Products for genes affiliated with Haemophilus Influenzae

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Sources for Haemophilus Influenzae

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet