MCID: HRN019
MIFTS: 14

Hair-an Syndrome malady

Category: Skin diseases

Aliases & Classifications for Hair-an Syndrome

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Aliases & Descriptions for Hair-an Syndrome:

Name: Hair-an Syndrome 46 66
Hyperandrogenism , Insulin Resistance , and Acanthosis Nigricans 46
 
Hyperandrogenic, Insulin-Resistant Acanthosis Nigricans Syndrome 46

Classifications:



Summaries for Hair-an Syndrome

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NIH Rare Diseases:46 Hair-an syndrome is a condition that affects women. it is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. insulin resistance is a condition in which the body produces insulin but does not use it properly. this causes the pancreas to produce more insulin. high levels of insulin stimulate the ovaries to make too much androgen, leading too excessive  hair growth, acne, and irregular periods. insulin resistance can also lead to diabetes, high blood pressure, heart disease, and excessive growth and darkening of the skin (aconthosis nigricans). women with hair-an may be born with insulin resistance or acquire it over time. last updated: 5/27/2011

MalaCards based summary: Hair-an Syndrome, also known as hyperandrogenism , insulin resistance , and acanthosis nigricans, is related to acanthosis nigricans and hyperandrogenism, and has symptoms including decreased libido and increased libido. Affiliated tissues include ovary, skin and pancreas.

Related Diseases for Hair-an Syndrome

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Diseases in the Hair Disease family:

hair-an syndrome

Diseases related to Hair-an Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1acanthosis nigricans9.9
2hyperandrogenism9.8
3mood disorder9.7

Symptoms for Hair-an Syndrome

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UMLS symptoms related to Hair-an Syndrome:


decreased libido, increased libido

Drugs & Therapeutics for Hair-an Syndrome

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Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Hair-an Syndrome

Genetic Tests for Hair-an Syndrome

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Anatomical Context for Hair-an Syndrome

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MalaCards organs/tissues related to Hair-an Syndrome:

34
Ovary, Skin, Pancreas, Heart

Animal Models for Hair-an Syndrome or affiliated genes

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Publications for Hair-an Syndrome

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Articles related to Hair-an Syndrome:

(show all 13)
idTitleAuthorsYear
1
HAIR-AN syndrome in a male adolescent with concomitant vitiligo. (19380681)
2009
2
Navigating adolescence with a chronic health condition: a perspective on the psychological effects of HAIR-AN syndrome on adolescent girls. (17072487)
2006
3
Biliopancreatic diversion as a novel approach to the HAIR-AN syndrome. (15802076)
2005
4
Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome. (15258677)
2004
5
HAIR-AN syndrome: a multisystem challenge. (11430453)
2001
6
Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: an 11-year follow-up. (10474728)
1999
7
Development of diabetes mellitus and hypertension due to aggravation of insulin resistance after estrogen--progestogen in HAIR-AN syndrome. (11229194)
1997
8
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy. (9126004)
1997
9
Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl. (8621823)
1996
10
HAIR-AN syndrome and mental disorders. (8555759)
1995
11
HAIR-AN syndrome]. (7983793)
1994
12
Effect of ketoconazole in the hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome. (1430411)
1992
13
Organic mood disorder associated with the HAIR-AN syndrome. (1627962)
1992

Variations for Hair-an Syndrome

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Expression for genes affiliated with Hair-an Syndrome

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Search GEO for disease gene expression data for Hair-an Syndrome.

Pathways for genes affiliated with Hair-an Syndrome

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GO Terms for genes affiliated with Hair-an Syndrome

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Sources for Hair-an Syndrome

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2CDC
6CNVD
10DGIdb
15ExPASy
16FDA
17FMA
25GTR
26HGMD
27HMDB
28ICD10
29ICD10 via Orphanet
30ICD9CM
31IUPHAR
32KEGG
35MedGen
37MeSH
38MESH via Orphanet
39MGI
42NCI
43NCIt
44NDF-RT
47NINDS
48Novoseek
50OMIM
51OMIM via Orphanet
55PubMed
56QIAGEN
61SNOMED-CT via Orphanet
65Tumor Gene Family of Databases
66UMLS
67UMLS via Orphanet