MCID: HRN019
MIFTS: 18

Hair-an Syndrome malady

Rare diseases, Skin diseases categories

Summaries for Hair-an Syndrome

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NIH Rare Diseases:43 Hair-an syndrome is a condition that affects women. it is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. insulin resistance is a condition in which the body produces insulin but does not use it properly. this causes the pancreas to produce more insulin. high levels of insulin stimulate the ovaries to make too much androgen, leading too excessive  hair growth, acne, and irregular periods. insulin resistance can also lead to diabetes, high blood pressure, heart disease, and excessive growth and darkening of the skin (aconthosis nigricans). women with hair-an may be born with insulin resistance or acquire it over time. last updated: 5/27/2011

MalaCards based summary: Hair-an Syndrome, also known as hyperandrogenism , insulin resistance , and acanthosis nigricans, is related to obesity and polycystic ovary syndrome. An important gene associated with Hair-an Syndrome is INS (insulin). Affiliated tissues include heart, pancreas and skin.

Aliases & Classifications for Hair-an Syndrome

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Hair-an Syndrome, Aliases & Descriptions:

Name: Hair-an Syndrome 43
Hyperandrogenism , Insulin Resistance , and Acanthosis Nigricans 43
 
Hyperandrogenic, Insulin-Resistant Acanthosis Nigricans Syndrome 43


Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Rare diseases
Anatomical: Skin diseases


Related Diseases for Hair-an Syndrome

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Diseases in the Hair Disease family:

hair-an syndrome

Diseases related to Hair-an Syndrome via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1obesity10.5
2polycystic ovary syndrome10.5
3ovarian stromal hyperthecosis10.5
4acanthosis nigricans10.2
5hyperandrogenism10.1
6mood disorder10.0

Graphical network of diseases related to Hair-an Syndrome:



Diseases related to hair-an syndrome

Symptoms for Hair-an Syndrome

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Drugs & Therapeutics for Hair-an Syndrome

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Drug clinical trials:

Search ClinicalTrials for Hair-an Syndrome

Search NIH Clinical Center for Hair-an Syndrome

Genetic Tests for Hair-an Syndrome

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Anatomical Context for Hair-an Syndrome

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MalaCards organs/tissues related to Hair-an Syndrome:

33
Heart, Pancreas, Skin, Ovary

Animal Models for Hair-an Syndrome or affiliated genes

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Publications for Hair-an Syndrome

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Articles related to Hair-an Syndrome:

(show all 13)
idTitleAuthorsYear
1
HAIR-AN syndrome in a male adolescent with concomitant vitiligo. (19380681)
2009
2
Navigating adolescence with a chronic health condition: a perspective on the psychological effects of HAIR-AN syndrome on adolescent girls. (17072487)
2006
3
Biliopancreatic diversion as a novel approach to the HAIR-AN syndrome. (15802076)
2005
4
Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome. (15258677)
2004
5
HAIR-AN syndrome: a multisystem challenge. (11430453)
2001
6
Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: an 11-year follow-up. (10474728)
1999
7
Development of diabetes mellitus and hypertension due to aggravation of insulin resistance after estrogen--progestogen in HAIR-AN syndrome. (11229194)
1997
8
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy. (9126004)
1997
9
Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl. (8621823)
1996
10
HAIR-AN syndrome and mental disorders. (8555759)
1995
11
HAIR-AN syndrome]. (7983793)
1994
12
Organic mood disorder associated with the HAIR-AN syndrome. (1627962)
1992
13
Effect of ketoconazole in the hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome. (1430411)
1992

Variations for Hair-an Syndrome

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Expression for genes affiliated with Hair-an Syndrome

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Search GEO for disease gene expression data for Hair-an Syndrome.

Pathways for genes affiliated with Hair-an Syndrome

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Compounds for genes affiliated with Hair-an Syndrome

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GO Terms for genes affiliated with Hair-an Syndrome

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Products for genes affiliated with Hair-an Syndrome

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies
  • Proteins
  • Kits and Assays

Sources for Hair-an Syndrome

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4CDC
15ExPASy
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
52PubMed
53QIAGEN
58SNOMED-CT via Orphanet
62UMLS
63UMLS via Orphanet