MCID: HRN019
MIFTS: 16

Hair-an Syndrome

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Hair-an Syndrome

MalaCards integrated aliases for Hair-an Syndrome:

Name: Hair-an Syndrome 49 69
Hyperandrogenism , Insulin Resistance , and Acanthosis Nigricans 49
Hyperandrogenic, Insulin-Resistant Acanthosis Nigricans Syndrome 49

Classifications:



External Ids:

UMLS 69 C1963745

Summaries for Hair-an Syndrome

NIH Rare Diseases : 49 HAIR-AN syndrome is a condition that affects women. It is characterized by hyperandrogenism, insulin resistance, and acanthosis nigricans. Insulin resistance is a condition in which the body produces insulin but does not use it properly. This causes the pancreas to produce more insulin. High levels of insulin stimulate the ovaries to make too much androgen, leading too excessive  hair growth, acne, and irregular periods. Insulin resistance can also lead to diabetes, high blood pressure, heart disease, and excessive growth and darkening of the skin (aconthosis nigricans). Women with HAIR-AN may be born with insulin resistance or acquire it over time. Last updated: 5/27/2011

MalaCards based summary : Hair-an Syndrome, also known as hyperandrogenism , insulin resistance , and acanthosis nigricans, is related to acanthosis nigricans and hyperandrogenism. Affiliated tissues include ovary, skin and pancreas.

Wikipedia : 72 HAIR-AN syndrome consists of hyperandrogenism (HA), insulin resistance (IR), and acanthosis nigricans... more...

Related Diseases for Hair-an Syndrome

Diseases in the Hair Disease family:

Hair-an Syndrome

Diseases related to Hair-an Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 acanthosis nigricans 9.8
2 hyperandrogenism 9.8
3 vitiligo-associated multiple autoimmune disease susceptibility 1 9.6
4 diabetes mellitus 9.6
5 disease of mental health 9.6
6 mood disorder 9.6

Graphical network of the top 20 diseases related to Hair-an Syndrome:



Diseases related to Hair-an Syndrome

Symptoms & Phenotypes for Hair-an Syndrome

Drugs & Therapeutics for Hair-an Syndrome

Search Clinical Trials , NIH Clinical Center for Hair-an Syndrome

Genetic Tests for Hair-an Syndrome

Anatomical Context for Hair-an Syndrome

MalaCards organs/tissues related to Hair-an Syndrome:

38
Ovary, Skin, Pancreas, Heart

Publications for Hair-an Syndrome

Articles related to Hair-an Syndrome:

(show all 13)
# Title Authors Year
1
HAIR-AN syndrome in a male adolescent with concomitant vitiligo. ( 19380681 )
2009
2
Navigating adolescence with a chronic health condition: a perspective on the psychological effects of HAIR-AN syndrome on adolescent girls. ( 17072487 )
2006
3
Biliopancreatic diversion as a novel approach to the HAIR-AN syndrome. ( 15802076 )
2005
4
Clinical profiles, occurrence, and management of adolescent patients with HAIR-AN syndrome. ( 15258677 )
2004
5
HAIR-AN syndrome: a multisystem challenge. ( 11430453 )
2001
6
Clearance of acanthosis nigricans associated with the HAIR-AN syndrome after partial pancreatectomy: an 11-year follow-up. ( 10474728 )
1999
7
Successful treatment of hirsutism in HAIR-AN syndrome using flutamide, spironolactone, and birth control therapy. ( 9126004 )
1997
8
Development of diabetes mellitus and hypertension due to aggravation of insulin resistance after estrogen--progestogen in HAIR-AN syndrome. ( 11229194 )
1997
9
Hyperandrogenism, insulin resistance, and acanthosis nigricans (HAIR-AN) syndrome: spontaneous remission in a 15-year-old girl. ( 8621823 )
1996
10
HAIR-AN syndrome and mental disorders. ( 8555759 )
1995
11
[HAIR-AN syndrome]. ( 7983793 )
1994
12
Organic mood disorder associated with the HAIR-AN syndrome. ( 1627962 )
1992
13
Effect of ketoconazole in the hyperandrogenism, insulin resistance and acanthosis nigricans (HAIR-AN) syndrome. ( 1430411 )
1992

Variations for Hair-an Syndrome

Expression for Hair-an Syndrome

Search GEO for disease gene expression data for Hair-an Syndrome.

Pathways for Hair-an Syndrome

GO Terms for Hair-an Syndrome

Sources for Hair-an Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
Content
Loading form....