MCID: HRD018
MIFTS: 33

Hair Disease malady

Skin category

Summaries for Hair Disease

Sources:
8Disease Ontology, 64Wikipedia, 33MalaCards
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Wikipedia:64 Hair diseases are disorders primarily associated with the follicles of the hair. more...

MalaCards: Hair Disease, also known as hair disorder, is related to menkes disease and wilson disease. An important gene associated with Hair Disease is KRT86 (keratin 86). The compounds sodium azide and carnitine have been mentioned in the context of this disorder. Affiliated tissues include hair.

Disease Ontology:8 An integumentary system disease that is located in hair.

Aliases & Classifications for Hair Disease

Sources:
8Disease Ontology, 45Novoseek, 61UMLS, 57SNOMED-CT, 35MeSH, 40NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin


Aliases & Descriptions:

hair disease 8
hair disorder 45
hair diseases 61


External Ids:

Disease Ontology8 DOID:421
MeSH35 D006201
NCIt40 C34656
ICD1025 L67.9

Related Diseases for Hair Disease

Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hair Disease:



Diseases related to hair disease

Clinical Features for Hair Disease

Drugs & Therapeutics for Hair Disease

Sources:
5CenterWatch, 42NIH Clinical Center, 6ClinicalTrials, 61UMLS, 41NDF-RT
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Approved drugs:

Search CenterWatch for Hair Disease

Drug clinical trials:

Search ClinicalTrials for Hair Disease

Search NIH Clinical Center for Hair Disease

Search CenterWatch for Hair Disease

Genetic Tests for Hair Disease

Anatomical Context for Hair Disease

Sources:
14FMA
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FMA organs/tissues related to Hair Disease:

14
Hair

Animal Models for Hair Disease or affiliated genes

Sources:
28inGenious Targeting Laboratory
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Publications for Hair Disease

Sources:
51PubMed
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Articles related to Hair Disease:

(show top 50)    (show all 185)
idTitleAuthorsYear
1
Cartilage hair hypoplasia and celiac disease: report of an Indian girl with novel genotype. (23949991)
2013
2
Development of autoimmune hair loss disease alopecia areata is associated with cardiac dysfunction in C3H/HeJ mice. (23658656)
2013
3
Combating cancer predisposition in association with idiopathic immune deficiency: a recurrent nodal and cutaneous T-cell lymphoproliferative disease in a patient with cartilage-hair hypoplasia. (22999941)
2013
4
Monitoring the disease activity in pemphigus by direct immunofluorescence of plucked hair: a pilot study. (23716856)
2013
5
Menkes kinky hair disease. (23112368)
2012
6
Hair care practices and scalp/hair disease in African American girls. (21571179)
2011
7
Rituximab with pentostatin or cladribine: an effective combination treatment for hairy cell leukemia after disease recurrence. (21504288)
2011
8
Definition of remission, minimal residual disease, and relapse in hairy cell leukemia bone marrow biopsy histology and immunohistology specimens. (21463123)
2011
9
Very long-term eradication of minimal residual disease in patients with hairy cell leukemia after a single course of cladribine. (20056789)
2010
10
Familial woolly hair disease. (20519796)
2010
11
Black hairy tongue after allogeneic stem cell transplantation: an unrecognized cutaneous presentation of graft-versus-host disease. (21168745)
2010
12
Trichothiodystrophy and fragile hair: the distinction between diagnostic signs and diagnostic labels in childhood hair disease. (19754869)
2009
13
Characterization and in vitro reaction properties of 19 unique hairpin telomeres from the linear plasmids of the lyme disease spirochete. (19122193)
2009
14
Multiplex detection and genotyping of point mutations involved in charcot-marie-tooth disease using a hairpin microarray-based assay. (22820753)
2009
15
Localized bone disease as a presentation of hairy cell leukemia. (18496495)
2008
16
The disease with hope: hairy cell leukemia. (17962181)
2007
17
Potential predictive patterns of minimal residual disease detected by immunohistochemistry on bone marrow biopsy specimens during a long-term follow-up in patients treated with cladribine for hairy cell leukemia. (16519567)
2006
18
Hairy cell leukemia: survival and relapse. Long-term follow-up of purine analog-based therapy and approach for relapsed disease. (15737878)
2005
19
Psychological aspects of hair disease. (17166214)
2005
20
Hairy cell leukemia with large cells: long disease course with adequate response to therapy. (15385931)
2004
21
Impact of preventive strategies on trend of occupational skin disease in hairdressers: population based register study. (12065264)
2002
22
A case of hairy cell leukemia resembling asymptomatic chronic liver disease on presentation. (9923103)
1998
23
Familial hairy cell leukemia: a HLA-linked disease or farmers-linked disease? (9793263)
1998
24
Red cell distribution width (RDW) as a marker of disease activity in patients with hairy cell leukemia. (9588069)
1998
25
Hairy cell leukemia without splenomegaly nor myelofibrosis in a patient with gastric adenocarcinoma: early phase of the disease or a variant? (7567177)
1995
26
Rapid hair regrowth in refractory alopecia universalis associated with autoimmune disease following liver transplantation and tacrolimus (FK506) therapy. (7539169)
1995
27
Cerebellar superoxide dismutase expression in Menkes' kinky hair disease: an immunohistochemical investigation. (7484097)
1995
28
Menkes kinky hair disease. (8028455)
1994
29
Tufted hair folliculitis: a specific disease? (8123584)
1994
30
Cytochrome C oxidase deficiency and neuronal involvement in Menkes' kinky hair disease: immunohistochemical study. (8293191)
1993
31
Extensive human papillomavirus-related disease (bowenoid papulosis, Bowen's disease, and squamous cell carcinoma) in a patient with hairy cell leukemia: clinical and immunologic evaluation after an interferon alfa trial. (8408802)
1993
32
Menkes' kinky hair disease: morphological and immunohistochemical comparison of two autopsied patients. (2028748)
1991
33
Decreased blood flow and oxygen metabolism in the cerebellum, brain stem and thalamus in a case with Menkes kinky hair disease. (2618967)
1989
34
Atypical Menkes steely hair disease. (3189407)
1988
35
Catecholamine metabolism in kinky hair disease. (3233105)
1988
36
Cerebral lipid and protein abnormalities in Menkes' steely-hair disease. (3599492)
1986
37
Copper-binding proteins in the liver and kidney from the patients with Menkes' kinky hair disease. (6836561)
1983
38
Menkes' kinky hair disease. I. Comparison of classical and unusual clinical and biochemical features in two patients. (7091567)
1982
39
Tissue copper concentrations of patients with Menke's kinky hair disease. (7211802)
1981
40
Polyamine metabolism in Menkes kinky hair disease. (6772349)
1980
41
Kinky hair disease. Biochemical, histochemical, and ultrastructural studies. (514687)
1979
42
Failure of human milk therapy in Menkes' kinky hair disease. (581719)
1979
43
Inborn errors of copper metabolism: kinky hair disease and hepatolenticular degeneration. Therapeutic approaches. (979354)
1976
44
Menkes' kinky hair disease: a light and electron microscopic study of the eye. (1245386)
1976
45
Fine structural changes in the cerebellar cortex in kinky hair disease. (1028277)
1976
46
Study of copper metabolism in kinky hair disease (Menkes' disease) and in hepatolenticular degeneration (Wilson's disease) utilizing 67Cu and radioactivity counting in the total body and various tissues. (4219083)
1974
47
Menkes' kinky hair disease: further definition of the defect in copper transport. (4120259)
1973
48
Argininosuccinic aciduria in hereditary hair diseases. (4185293)
1968
49
Kinky hair disease. I. Clinical and pathological features. (5922550)
1966
50
Endocrine diseases of the dog associated with hair loss: Sertoli cell tumor of testis, hypothyroidism, canine Cushing's syndrome. (13108799)
1953

Genetic Variations for Hair Disease

Expression for genes affiliated with Hair Disease

Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hair Disease

Search GEO for disease gene expression data for Hair Disease.

Pathways for genes affiliated with Hair Disease

Compounds for genes affiliated with Hair Disease

Sources:
45Novoseek, 24HMDB
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Compounds related to Hair Disease according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1sodium azide459.4CP, COX5A
2carnitine459.4CP, COX5A
3copper histidine458.9COX5A, ATP7A, CP
4copper45 249.9ATP7A, COX5A, CP
5superoxide45 249.5COX5A, ATP7A, CP
6glutamate458.1COX5A, CNP, KRT86, CP

GO Terms for genes affiliated with Hair Disease

Sources:
16Gene Ontology
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Cellular components related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.6KRT81, KRT86

Biological processes related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion transportGO:0068259.3CP, ATP7A

Molecular functions related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion bindingGO:0055079.3CP, ATP7A

Products for genes affiliated with Hair Disease

  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hair Disease

3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
29IUPHAR
30KEGG
35MeSH
36MESH via Orphanet
37MGI
40NCIt
41NDF-RT
44NINDS
45Novoseek
47OMIM
48OMIM via Orphanet
51PubMed
52QIAGEN
58SNOMED-CT via Orphanet
61UMLS
62UMLS via Orphanet