MCID: HRD018
MIFTS: 51

Hair Disease malady

Categories: Skin diseases, Rare diseases

Aliases & Classifications for Hair Disease

Aliases & Descriptions for Hair Disease:

Name: Hair Disease 12 29 14
Hair Diseases 42 69
Hair Disorder 52
Hair Problems 41

Classifications:



External Ids:

Disease Ontology 12 DOID:421
MeSH 42 D006201
NCIt 47 C34656
ICD10 33 L67.9
UMLS 69 C0018500

Summaries for Hair Disease

MedlinePlus : 41 the average person has 5 million hairs. hair grows all over your body except on your lips, palms, and the soles of your feet. it takes about a month for healthy hair to grow half an inch. most hairs grow for up to six years and then fall out. new hairs grow in their place. hair helps keep you warm. it also protects your eyes, ears and nose from small particles in the air. common problem with the hair and scalp include hair loss, infections, and flaking.

MalaCards based summary : Hair Disease, also known as hair diseases, is related to menkes disease and ringed hair, and has symptoms including exanthema and pruritus. An important gene associated with Hair Disease is KRT86 (Keratin 86), and among its related pathways/superpathways are Keratinization and Platinum Pathway, Pharmacokinetics/Pharmacodynamics. The drugs Dopamine and Methylphenidate have been mentioned in the context of this disorder. Affiliated tissues include eye, skin and brain, and related phenotypes are craniofacial and integument

Disease Ontology : 12 An integumentary system disease that is located in hair.

Wikipedia : 71 Hair diseases are disorders primarily associated with the follicles of the... more...

Related Diseases for Hair Disease

Diseases in the Hair Disease family:

Hair-an Syndrome

Diseases related to Hair Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 36)
id Related Disease Score Top Affiliating Genes
1 menkes disease 11.4
2 ringed hair 10.8
3 monilethrix 10.8
4 hypotrichosis 7 10.5
5 hypertrichosis 10.5
6 hypotrichosis 10.5
7 trichomalacia 10.5
8 pallister-killian syndrome 10.3 DSP KRT74
9 17-alpha-hydroxylase-deficient congenital adrenal hyperplasia 10.3 LIPH LPAR6
10 autism x-linked 4 10.3 MBTPS2 SAT1
11 epidermolysis bullosa, lethal acantholytic 10.3 DSP KRT74
12 sinoatrial node disease 10.2 DSG4 KRT74
13 anemia, hypochromic microcytic 10.2 HOXC13 KRT74
14 hypotrichosis 3 10.2 KRT74 LIPH LPAR6
15 x-linked intellectual disability with or without nystagmus 10.2 DSP KRT74 LIPH LPAR6
16 complex partial epilepsy 10.2 MBTPS2 SAT1
17 congenital disorder of glycosylation, type iij 10.2 CDH15 CDH3
18 mitochondrial complex deficiency, nuclear type 4 10.2 DSG4 KRT74 LIPH LPAR6
19 spastic paraplegia 14, autosomal recessive 10.1 DSG4 KRT74 LIPH LPAR6
20 congenital disorder of glycosylation, type ip 10.1 DSG4 KRT74 LIPH LPAR6
21 fallopian tube disease 10.1 CDH15 LIPH
22 ichthyosis, acquired 10.1 DSG4 KRT74 LIPH LPAR6
23 klebsiella infection 10.1 MBTPS2 SAT1
24 cataract 15, multiple types 10.1 DSG4 KRT74 KRT81 KRT86 LPAR6
25 anaplastic large cell lymphoma 10.0 DCAF17 DSP MBTPS2 VDR
26 microcornea, myopic chorioretinal atrophy, and telecanthus 10.0 CDH15 CDH3
27 mesenchymal chondrosarcoma 9.8 CDH3 DCAF17 DSG4 KRT74 KRT86 LIPH
28 cerebritis 9.6
29 neuronitis 9.6
30 argininosuccinic aciduria 9.4
31 ataxia-telangiectasia 9.4
32 hepatitis 9.4
33 bladder diverticulum 9.4
34 cerebellar degeneration 9.4
35 ataxia 9.4
36 pyoderma 8.6 ANTXR1 ATP7A ATP7B CDH15 CDH3 CNP

Graphical network of the top 20 diseases related to Hair Disease:



Diseases related to Hair Disease

Symptoms & Phenotypes for Hair Disease

UMLS symptoms related to Hair Disease:


exanthema, pruritus

MGI Mouse Phenotypes related to Hair Disease:

44
id Description MGI Source Accession Score Top Affiliating Genes
1 craniofacial MP:0005382 9.63 ANTXR1 ATP7A DSP ERCC3 HOXC13 VDR
2 integument MP:0010771 9.61 HOXC13 LIPH VDR ATP7A ATP7B CDH3
3 reproductive system MP:0005389 9.23 ANTXR1 ATP7A ATP7B CNP ERCC3 LPP

Drugs & Therapeutics for Hair Disease

Drugs for Hair Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 535)
id Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 4 51-61-6, 62-31-7 681
2
Methylphenidate Approved, Investigational Phase 4 113-45-1 4158
3
Ciclopirox Approved, Investigational Phase 4 29342-05-0 2749
4
Isotretinoin Approved Phase 4,Phase 1 4759-48-2 5538 5282379
5
Miconazole Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 22916-47-8 4189
6
Salicylic acid Approved, Vet_approved Phase 4 69-72-7 338
7
Propofol Approved, Investigational, Vet_approved Phase 4,Phase 3 2078-54-8 4943
8
Remifentanil Approved Phase 4,Phase 3 132875-61-7 60815
9
Sevoflurane Approved, Vet_approved Phase 4 28523-86-6 5206
10
Minoxidil Approved Phase 4,Phase 3,Phase 1,Phase 2 38304-91-5 4201
11
Methylprednisolone Approved, Vet_approved Phase 4 83-43-2 6741
12
Prednisolone Approved, Vet_approved Phase 4 50-24-8 5755
13
Lidocaine Approved, Vet_approved Phase 4,Phase 1 137-58-6 3676
14
Hydrocortisone Approved, Vet_approved Phase 4,Phase 3 50-23-7 5754 657311
15
Triamcinolone Approved, Vet_approved Phase 4,Phase 2 124-94-7 31307
16
Finasteride Approved Phase 4,Phase 3,Phase 1,Phase 2 98319-26-7 57363
17
Bimatoprost Approved, Investigational Phase 4,Phase 3,Phase 2,Phase 1 155206-00-1 5311027
18
Ketoconazole Approved, Investigational Phase 4 65277-42-1 47576 3823
19
Betamethasone Approved, Vet_approved Phase 4,Phase 2 378-44-9 9782
20
Latanoprost Approved, Investigational Phase 4 130209-82-4 5282380 5311221
21
Hydroxychloroquine Approved Phase 4 118-42-3 3652
22
Capsaicin Approved Phase 4,Phase 1 404-86-4 1548943
23
Imiquimod Approved, Investigational Phase 4 99011-02-6 57469
24
Cephalexin Approved, Vet_approved Phase 4 15686-71-2 27447
25
Clindamycin Approved, Vet_approved Phase 4,Phase 3 18323-44-9 29029
26
Prilocaine Approved Phase 4 721-50-6 4906
27
Tetracaine Approved, Vet_approved Phase 4 94-24-6 5411
28
Olanzapine Approved, Investigational Phase 4 132539-06-1 4585
29
Desonide Approved, Investigational Phase 4 638-94-8 5311066
30
Sertraline Approved Phase 4 79617-96-2 68617
31
Pregabalin Approved, Illicit, Investigational Phase 4,Phase 2 148553-50-8 5486971
32
Drospirenone Approved Phase 4,Phase 2 67392-87-4 68873
33
Estradiol Approved, Investigational, Vet_approved Phase 4,Phase 3,Phase 2 50-28-2 5757 53477783
34
Ethinyl Estradiol Approved Phase 4,Phase 2 57-63-6 5991
35
Doxorubicin Approved, Investigational Phase 4,Phase 2 23214-92-8 31703
36
Pioglitazone Approved, Investigational Phase 4 111025-46-8 4829
37
Darunavir Approved Phase 4,Phase 3 635728-49-3, 206361-99-1 213039
38
Pravastatin Approved Phase 4,Phase 2 81093-37-0 54687
39
Ritonavir Approved, Investigational Phase 4,Phase 3 155213-67-5 392622
40
Benzocaine Approved Phase 4 1994-09-7, 94-09-7 2337
41
Ropivacaine Approved Phase 4,Phase 3 84057-95-4 71273 175805
42
Spironolactone Approved Phase 4,Phase 2 1952-01-7, 52-01-7 5833
43
Lovastatin Approved, Investigational Phase 4 75330-75-5 53232
44
Clonidine Approved Phase 4 4205-90-7 2803
45
Ketamine Approved, Vet_approved Phase 4 6740-88-1 3821
46
Aminolevulinic acid Approved Phase 4 106-60-5 137
47
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Phase 3,Phase 2 59-30-3 6037
48 tannic acid Approved, Nutraceutical Phase 4
49
Doxil Approved June 1999 Phase 4,Phase 2 31703
50 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1

Interventional clinical trials:

(show top 50) (show all 690)
id Name Status NCT ID Phase
1 Safety and Efficacy of Clobetasol Propionate 0.05% E Foam in Alopecia Unknown status NCT01111981 Phase 4
2 Methylphenidate in ADHD With Trichotillomania Unknown status NCT00552266 Phase 4
3 NIMIP: Non Invasive Measurement of the Intracranial Pressure Unknown status NCT01685450 Phase 4
4 Efficacy and Safety of Low-dose Oral Isotretinoin for Seborrhea Unknown status NCT01139749 Phase 4
5 Effect of Propofol on Remifentanil-induced Postoperative Hyperalgesia in Patients Undergoing Thyroid Surgery Unknown status NCT01189721 Phase 4
6 Pilot Study of a Novel IPL for Removal of Unwanted Fine Body Hair Completed NCT01912950 Phase 4
7 Minoxidil 1% for Eyebrow Enhancement Completed NCT01924000 Phase 4
8 Minoxidil 2% for Eyebrow Enhancement Completed NCT01672307 Phase 4
9 Safety and Efficacy of Bimatoprost 0.03% Solution for the Treatment of Thinning Eyebrows Completed NCT01891487 Phase 4
10 Study Assessing Patient Satisfaction With LATISSE® for Increasing Eyelash Prominence Completed NCT01448525 Phase 4
11 Latisse (Bimatoprost .03% Opthalmic Solution) for the Treatment of Hypotrichosis of the Eyebrows: Latisse Versus Placebo Completed NCT01387906 Phase 4
12 Safety and Efficacy of LATISSE® in the Augmentation of Eyelashes of Korean Subjects Completed NCT01229423 Phase 4
13 Study of Bimatoprost Solution in Increasing Eyelash Prominence in African Americans With Eyelash Hypotrichosis Completed NCT00958035 Phase 4
14 Safety and Efficacy of Ketoconazole 2% Foam in the Treatment of Pityrosporum Folliculitis Completed NCT00824863 Phase 4
15 Safety and Efficacy of Bimatoprost Solution in Treating Eyelash Loss or Hypotrichosis in Children Completed NCT01023841 Phase 4
16 Comparison of Topical Latanoprost vs Topical Corticosteroid in Treatment of Localized Alopecia Areata Completed NCT02350023 Phase 4
17 Plaquenil for Alopecia Areata, Alopecia Totalis Completed NCT00176982 Phase 4
18 Response of Topical Capsaicin in Alopecia Areata Completed NCT00176969 Phase 4
19 Treatment With Topical Eflornithin After Laser Treatment in Women With Facial Hirsutism Completed NCT01817894 Phase 4
20 Evaluation of Eflornithine on Facial and Forearm Skin Completed NCT00152048 Phase 4
21 Aldara for the Treatment of Extensive Alopecia Areata Completed NCT00177021 Phase 4
22 Safety and Efficacy of Oral Mega Pulse Methylprednisolone in Severe Therapy Resistant Alopecia Areata Completed NCT01167946 Phase 4
23 Characteristics of T Cells From Alopecia Areata Scalp Skin Before and After Treatment With Aldara 5% Completed NCT00176943 Phase 4
24 Comparison of Cephalexin Versus Clindamycin for Suspected CA-MRSA Skin Infections Completed NCT00352612 Phase 4
25 Study of Wound Packing After Superficial Skin Abscess Drainage Completed NCT00746109 Phase 4
26 Twice Daily Altabax Application for the Treatment of Uncomplicated Soft Tissue Infection Completed NCT01126268 Phase 4
27 The Efficacy of Laser Assisted Hair Removal in the Treatment of Acne Keloidalis Nuchae; a Pilot Study Completed NCT01548898 Phase 4
28 7% Lidocaine/7% Tetracaine Cream Versus 2,5% Lidocaine / 2,5% Prilocaine Cream Completed NCT02372786 Phase 4
29 Olanzapine in the Treatment of Hair Pulling (Trichotillomania) Completed NCT00182507 Phase 4
30 Efficacy and Tolerability of New Topical Formulations in Subjects With Atopic Dermatitis Completed NCT02732314 Phase 4
31 Sertraline and Habit Reversal in the Treatment of Patients With Trichotillomania Completed NCT00118014 Phase 4
32 NIMI-NICU: Non Invasive Monitoring of the Intracranial Pressure - NeuroIntensive Care Unit Completed NCT01685476 Phase 4
33 Pregabalin in the Treatment of Essential Tremor Completed NCT00646451 Phase 4
34 Clinical, Metabolic and Endocrine Effects of the Treatment With Drospirenone and Ethinyl Estradiol Alone or in Combination With Myo-inositol in Young Women With Polycystic Ovary Syndrome (PCOS) and Insulin Resistance Completed NCT01511822 Phase 4
35 Pharmacokinetic (PK) and Tolerance Study of Natroba Topical Suspension in Pediatrics With an Active Head Lice Infestation Completed NCT01660321 Phase 4
36 Effect of Intraoperative Magnesium on Remifentanil-induced Postoperative Hyperalgesia After Thyroidectomy Completed NCT01025245 Phase 4
37 Trial of the Ovicidal Activity of Three Head Lice Products (NeutraLice Lotion®, NeutraLice Advance® and Moov Head Lice Solution®) After a Single Application Completed NCT00995124 Phase 4
38 Doxorubicin Pharmacokinetics and Response in Non Hodgkin's Lymphoma Completed NCT00969462 Phase 4
39 Pioglitazone Treatment in Polycystic Ovary Syndrome Completed NCT00145340 Phase 4
40 Genetic Predictors of Variability in the Drug-drug Interaction Between Darunavir/Ritonavir and Pravastatin Completed NCT00630734 Phase 4
41 Study Evaluating Whether the Bispectral Index Prevents Patients at Higher Risk From Being Awake During Surgery and Anesthesia Completed NCT00682825 Phase 4
42 Continuous TAP Blocks: Relative Effects of a Basal Infusion vs. Repeated Bolus Doses Completed NCT02662023 Phase 4
43 Intralesional Steroids in the Treatment of Alopecia Areata Recruiting NCT01898806 Phase 4
44 Combining Lovastatin and a Parent-Implemented Language Intervention for Fragile X Syndrome Recruiting NCT02642653 Phase 4
45 OFA - Opioid Free Anesthesia Recruiting NCT03124082 Phase 4
46 Comparing Different Platelet Rich Plasma (PRP) Treatment Regimens for Management of Androgenic Alopecia Active, not recruiting NCT02999737 Phase 4
47 Bilateral Comparison of Treatment of Facial Actinic Keratoses Using Microneedling and Photodynamic Therapy With Aminolevulinic Acid and Blue Light Versus Photodynamic Therapy With Aminolevulinic Acid and Blue Light Using Two Incubation Times Active, not recruiting NCT02622594 Phase 4
48 Acupuncture for Sedation in the Intensive Care Unit (ICU) Active, not recruiting NCT01362270 Phase 4
49 Immunodeficiency in Cartilage-hair Hypoplasia: Sub-project on Safety of Vaccination Against Chickenpox Enrolling by invitation NCT02383797 Phase 4
50 The Use of 5mg Finasteride Versus 200mg Spironolactone and Topical 5% Minoxidil in Treating Postmenopausal Female Androgenetic Alopecia Withdrawn NCT02483195 Phase 4

Search NIH Clinical Center for Hair Disease

Cochrane evidence based reviews: hair diseases

Genetic Tests for Hair Disease

Genetic tests related to Hair Disease:

id Genetic test Affiliating Genes
1 Abnormality of the Hair 29

Anatomical Context for Hair Disease

MalaCards organs/tissues related to Hair Disease:

39
Eye, Skin, Brain, Cortex, Liver, Kidney, Thalamus

The Foundational Model of Anatomy Ontology organs/tissues related to Hair Disease:

18
Hair

Publications for Hair Disease

Articles related to Hair Disease:

(show top 50) (show all 99)
id Title Authors Year
1
Ataxia telangiectasia, menkes kinky hair disease, neurocutaneous melanosis: a review of these neurocutaneous syndromes and indications for clinical practice. ( 27002302 )
2016
2
Menkes Kinky Hair Disease. ( 26840692 )
2016
3
Cerebellar expression of copper chaperone for superoxide, cytosolic cu/zn-superoxide dismutase, 4-hydroxy-2-nonenal, acrolein and heat shock protein 32 in patients with menkes kinky hair disease: immunohistochemical study. ( 25067875 )
2014
4
Menkes kinky hair disease. ( 23112368 )
2012
5
Hair care practices and scalp/hair disease in African American girls. ( 21571179 )
2011
6
Familial woolly hair disease. ( 20519796 )
2010
7
Trichothiodystrophy and fragile hair: the distinction between diagnostic signs and diagnostic labels in childhood hair disease. ( 19754869 )
2009
8
Menkes kinky hair disease: A case report. ( 18801184 )
2008
9
Menkes kinky hair disease (Menkes syndrome). A case report. ( 17053847 )
2006
10
Antiandrogen therapy for skin and hair disease. ( 16677962 )
2006
11
Psychological aspects of hair disease. ( 17166214 )
2005
12
Is kinky-hair disease a misnomer for Menkes syndrome? ( 11176670 )
2001
13
Menkes kinky hair disease: an unusual case. ( 10872109 )
2000
14
Hair today, gone tomorrow: transgenic mice with human repair deficient hair disease. ( 9657142 )
1998
15
Urologic abnormalities in Menkes' kinky hair disease: report of three cases. ( 9165480 )
1997
16
Menkes' kinky hair disease associated with a large bladder diverticulum: a case report. ( 9255676 )
1997
17
Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix. ( 9241275 )
1997
18
Kinky hair disease with multiple eruption cysts: a case report. ( 8936518 )
1996
19
Menkes' Kinky Hair disease: new considerations. ( 9141833 )
1996
20
Menkes' kinky-hair disease: radiologic findings in a patient treated with copper histidinate. ( 7704673 )
1995
21
Cerebellar superoxide dismutase expression in Menkes' kinky hair disease: an immunohistochemical investigation. ( 7484097 )
1995
22
Menkes kinky hair disease. ( 8028455 )
1994
23
Histochemical study of mitochondrial enzymes in cerebellar cortex of macular mutant mouse, a model of Menkes kinky hair disease. ( 8009964 )
1994
24
Copper distribution in fetus and placenta of the macular mutant mouse as a model of Menkes kinky hair disease. ( 7873696 )
1994
25
Intracellular distribution of hepatic copper in macular mutant mice. An animal model of Menkes' kinky-hair disease. ( 7688531 )
1993
26
Effect of age and sex on copper-induced toxicity in the macular mutant mouse. An animal model for Menkes' kinky-hair disease. ( 7509170 )
1993
27
Cytochrome C oxidase deficiency and neuronal involvement in Menkes' kinky hair disease: immunohistochemical study. ( 8293191 )
1993
28
The decreased immune responses in macular mouse, a model of Menkes' kinky hair disease. ( 8434133 )
1993
29
Menkes kinky hair disease: characteristic MR angiographic findings. ( 8237696 )
1993
30
Metallothionein messenger RNA levels in the macular mutant mouse: an animal model of Menkes' kinky-hair disease. ( 1912099 )
1991
31
Copper-induced toxicity in macular mutant mouse: an animal model for Menkes' kinky-hair disease. ( 1871775 )
1991
32
Correction of cerebrospinal fluid copper in Menkes kinky hair disease. ( 1930426 )
1991
33
Menkes' kinky hair disease: morphological and immunohistochemical comparison of two autopsied patients. ( 2028748 )
1991
34
MR of progressive neurodegenerative change in treated Menkes' kinky hair disease. ( 2046911 )
1991
35
Urate oxidase activity and copper content in the liver of macular mutant mouse, a model animal for human congenital copper deficiency, Menkes' kinky hair disease. ( 1819648 )
1991
36
[A pathophysiological study of macular mutant mouse as a model of human Menkes kinky hair disease. I. Copper contents and copper dependent enzyme activities in various organs]. ( 2175632 )
1990
37
A comparative immunocytochemical study of human cerebellar cortex in X-chromosome-linked copper malabsorption (Menkes' kinky hair disease) and granule cell type cerebellar degeneration. ( 2511498 )
1989
38
Decreased blood flow and oxygen metabolism in the cerebellum, brain stem and thalamus in a case with Menkes kinky hair disease. ( 2618967 )
1989
39
Cerebral MR of Menkes kinky-hair disease. ( 2492723 )
1989
40
Menkes kinky hair disease with 'ragged red' fibers. ( 3234609 )
1988
41
Biochemical study on the brain of the macular mutant mouse as a model of Menkes' kinky hair disease. ( 2453126 )
1988
42
Atypical Menkes steely hair disease. ( 3189407 )
1988
43
Kinky hair disease: twenty five years later. ( 2839049 )
1988
44
Copper metabolism in the macular mutant mouse: an animal model of Menkes's kinky-hair disease. ( 3219371 )
1988
45
Catecholamine metabolism in kinky hair disease. ( 3233105 )
1988
46
Golgi study on brain of macular mutant mouse as a model of Menkes kinky hair disease. ( 3577690 )
1987
47
Metallothionein in kidney and liver of the macular mouse as an animal model of Menkes' kinky hair disease. ( 3449862 )
1987
48
Light and electron microscopic study on cerebellar cortex of macular mutant mouse as a model of Menkes kinky hair disease. ( 2821841 )
1987
49
Neuronal and vascular disorders of the brain and spinal cord in Menkes kinky hair disease. ( 3130871 )
1987
50
Cerebral lipid and protein abnormalities in Menkes' steely-hair disease. ( 3599492 )
1986

Variations for Hair Disease

Expression for Hair Disease

Search GEO for disease gene expression data for Hair Disease.

Pathways for Hair Disease

Pathways related to Hair Disease according to GeneCards Suite gene sharing:

id Super pathways Score Top Affiliating Genes
1
Show member pathways
11.81 DSG4 DSP KRT74 KRT81 KRT86
2 10.26 ATP7A ATP7B ERCC3

GO Terms for Hair Disease

Cellular components related to Hair Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 desmosome GO:0030057 9.16 DSG4 DSP
2 keratin filament GO:0045095 9.13 KRT74 KRT81 KRT86
3 intermediate filament GO:0005882 8.92 DSP KRT74 KRT81 KRT86

Biological processes related to Hair Disease according to GeneCards Suite gene sharing:

(show all 12)
id Name GO ID Score Top Affiliating Genes
1 single organismal cell-cell adhesion GO:0016337 9.65 CDH3 DSG4 DSP
2 metal ion transport GO:0030001 9.51 ATP7A ATP7B
3 lactation GO:0007595 9.5 ATP7A ATP7B VDR
4 intermediate filament cytoskeleton organization GO:0045104 9.49 DSP KRT74
5 response to copper ion GO:0046688 9.46 ATP7A ATP7B
6 copper ion transport GO:0006825 9.43 ATP7A ATP7B
7 adherens junction organization GO:0034332 9.43 CDH15 CDH3 DSP
8 cellular copper ion homeostasis GO:0006878 9.4 ATP7A ATP7B
9 copper ion import GO:0015677 9.37 ATP7A ATP7B
10 cornification GO:0070268 9.35 DSG4 DSP KRT74 KRT81 KRT86
11 copper ion export GO:0060003 9.16 ATP7A ATP7B
12 keratinization GO:0031424 9.1 CDH3 DSG4 DSP KRT74 KRT81 KRT86

Molecular functions related to Hair Disease according to GeneCards Suite gene sharing:

id Name GO ID Score Top Affiliating Genes
1 structural molecule activity GO:0005198 9.56 DSP KRT74 KRT81 KRT86
2 cation-transporting ATPase activity GO:0019829 9.16 ATP7A ATP7B
3 copper ion transmembrane transporter activity GO:0005375 8.96 ATP7A ATP7B
4 copper-exporting ATPase activity GO:0004008 8.62 ATP7A ATP7B

Sources for Hair Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 MedGen
42 MeSH
43 MESH via Orphanet
44 MGI
46 NCI
47 NCIt
48 NDF-RT
51 NINDS
52 Novoseek
54 OMIM
55 OMIM via Orphanet
59 PubMed
60 QIAGEN
65 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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