MCID: HRD018
MIFTS: 41

Hair Disease malady

Skin diseases category

Summaries for Hair Disease

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Sources:
8Disease Ontology, 33MedlinePlus, 63Wikipedia, 32MalaCards
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MedlinePlus:33 The average person has 5 million hairs. hair grows all over your body except on your lips, palms, and the soles of your feet. it takes about a month for healthy hair to grow half an inch. most hairs grow for up to six years and then fall out. new hairs grow in their place. hair helps keep you warm. it also protects your eyes, ears and nose from small particles in the air. common problem with the hair and scalp include hair loss, infections, and flaking.

MalaCards: Hair Disease, also known as hair disorder, is related to menkes disease and monilethrix. An important gene associated with Hair Disease is KRT86 (keratin 86). The compounds sodium azide and carnitine have been mentioned in the context of this disorder. Affiliated tissues include hair, eye and skin.

Disease Ontology:8 An integumentary system disease that is located in hair.

Wikipedia:63 Hair diseases are disorders primarily associated with the follicles of the hair. more...

Aliases & Classifications for Hair Disease

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Sources:
8Disease Ontology, 44Novoseek, 33MedlinePlus, 60UMLS, 56SNOMED-CT, 34MeSH, 39NCIt, 25ICD10
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Anatomical: Skin diseases


Aliases & Descriptions:

hair disease 8
hair disorder 44
hair problems 33
hair diseases 60


External Ids:

Disease Ontology8 DOID:421
MeSH34 D006201
NCIt39 C34656
ICD1025 L67.9

Related Diseases for Hair Disease

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Sources:
17GeneCards, 18GeneDecks
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Graphical network of the top 20 diseases related to Hair Disease:



Diseases related to hair disease

Clinical Features for Hair Disease

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Drugs & Therapeutics for Hair Disease

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials, 60UMLS, 40NDF-RT
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Approved drugs:

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Drug clinical trials:

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Search NIH Clinical Center for Hair Disease

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Genetic Tests for Hair Disease

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Anatomical Context for Hair Disease

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Sources:
32MalaCards, 14FMA
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MalaCards organs/tissues related to Hair Disease:

32
Eye, Skin, Brain, Cortex, Liver, Kidney, Testis, Placenta, Endothelial, T cells, Thalamus, Heart, Spinal cord, Cerebellum, Whole blood

FMA organs/tissues related to Hair Disease:

14
Hair

Animal Models for Hair Disease or affiliated genes

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Publications for Hair Disease

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Sources:
50PubMed
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Articles related to Hair Disease:

(show top 50)    (show all 138)
idTitleAuthorsYear
1
Cartilage hair hypoplasia and celiac disease: report of an Indian girl with novel genotype. (23949991)
2013
2
Menkes kinky hair disease. (23112368)
2012
3
Diffuse hair loss in Addison disease: a reason for X-linked adrenoleukodystrophy screening. (22507581)
2012
4
Hair care practices and scalp/hair disease in African American girls. (21571179)
2011
5
Hidradenitis suppurativa: a disease of the absent sebaceous gland? Sebaceous gland number and volume are significantly reduced in uninvolved hair follicles from patients with hidradenitis suppurativa. (21250966)
2011
6
Cytokeratin 15 expression in central, centrifugal, cicatricial alopecia: new observations in normal and diseased hair follicles. (21251039)
2011
7
Familial woolly hair disease. (20519796)
2010
8
Genetic determinants of hair color and Parkinson's disease risk. (19194882)
2009
9
Trichothiodystrophy and fragile hair: the distinction between diagnostic signs and diagnostic labels in childhood hair disease. (19754869)
2009
10
Antiandrogen therapy for skin and hair disease. (16677962)
2006
11
Maple syrup urine disease hair reveals the importance of 18-methyleicosanoic acid in cuticular delamination. (15725595)
2005
12
Is kinky-hair disease a misnomer for Menkes syndrome? (11176670)
2001
13
Mutations in the RNA component of RNase MRP cause a pleiotropic human disease, cartilage-hair hypoplasia. (11207361)
2001
14
Gene for arrhythmogenic right ventricular cardiomyopathy with diffuse nonepidermolytic palmoplantar keratoderma and woolly hair (Naxos disease) maps to 17q21. (9610536)
1998
15
Urologic abnormalities in Menkes' kinky hair disease: report of three cases. (9165480)
1997
16
Menkes' Kinky Hair disease: new considerations. (9141833)
1996
17
Menkes kinky hair disease. (8028455)
1994
18
Tufted hair folliculitis: a specific disease? (8123584)
1994
19
Intracellular distribution of hepatic copper in macular mutant mice. An animal model of Menkes' kinky-hair disease. (7688531)
1993
20
Cytochrome C oxidase deficiency and neuronal involvement in Menkes' kinky hair disease: immunohistochemical study. (8293191)
1993
21
Effect of age and sex on copper-induced toxicity in the macular mutant mouse. An animal model for Menkes' kinky-hair disease. (7509170)
1993
22
Menkes kinky hair disease: characteristic MR angiographic findings. (8237696)
1993
23
Menkes' disease: report of a case and determination of eumelanin and pheomelanin in hypopigmented hair. (1638075)
1992
24
Menkes' kinky hair disease: morphological and immunohistochemical comparison of two autopsied patients. (2028748)
1991
25
Cerebral MR of Menkes kinky-hair disease. (2492723)
1989
26
Decreased blood flow and oxygen metabolism in the cerebellum, brain stem and thalamus in a case with Menkes kinky hair disease. (2618967)
1989
27
Catecholamine metabolism in kinky hair disease. (3233105)
1988
28
Metallothionein in kidney and liver of the macular mouse as an animal model of Menkes' kinky hair disease. (3449862)
1987
29
Golgi study on brain of macular mutant mouse as a model of Menkes kinky hair disease. (3577690)
1987
30
Catecholamine metabolism in steely hair disease. (2941501)
1986
31
Structural changes of hair after incorporation of the proline analogue L-azetidine-2-carboxylic acid. A model of hair disease by alteration of primary structure. (2408388)
1985
32
Kinky hair disease with suspected pseudo-Bartter syndrome. (4061786)
1985
33
Mitochondrial abnormalities in Menkes' kinky hair disease (MKHD). Electron-microscopic study of the brain from an autopsy case. (6868958)
1983
34
Autoradiographic demonstration of the copper-accumulating tissues in mice with a defect homologous to Menkes' Kinky Hair disease. (6417634)
1983
35
Menkes' kinky hair disease. II. A clinicopathological report of three cases. (7091568)
1982
36
A defect in catecholamine metabolism in kinky-hair disease. (7137961)
1982
37
The selenium state of children. II. Selenium content of serum, whole blood, hair and the activity of erythrocyte glutathione peroxidase in dietetically treated patients with phenylketonuria and maple-syrup-urine disease. (668729)
1978
38
Cell culture studies of Menkes kinky hair disease. (699339)
1978
39
Menkes' syndrome (kinky hair disease) [proceedings]. (718236)
1978
40
Generalized giant axonal neuropathy: a filament-forming disease of neuronal, endothelial, glial, and schwann cells in a patient without kinky hair. (602684)
1977
41
Heterozygote detection in angiokeratoma corporis diffusum (Anderson-Fabry disease). Studies on plasma, leucocytes, and hair follicles. (404411)
1977
42
Menkes' kinky hair disease. (865681)
1977
43
Menkes' kinky (steely) hair disease. (588193)
1977
44
Kinky hair disease. Study of copper metabolism with use of 67Cu. (1180729)
1975
45
Neuropathologic aspects in Menkes' Kinky hair disease (trichopoliodystrophy). Menkes' Kinky hair disease. (4140481)
1974
46
Letter: Menkes' kinky hair disease treated with subcutaneous copper sulphate. (4140440)
1974
47
Kinky hair disease. (5045346)
1972
48
Argininosuccinic aciduria in hereditary hair diseases. (4185293)
1968
49
Kinky hair disease. I. Clinical and pathological features. (5922550)
1966
50
NETHERTON'S DISEASE; TRICHORRHEXIS INVAGINATA (BAMBOO HAIR), CONGENITAL ICHTHYOSIFORM ERYTHRODERMA AND THE ATOPIC DIATHESIS. A HISTOPATHOLOGIC STUDY. (14070837)
1964

Genetic Variations for Hair Disease

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Expression for genes affiliated with Hair Disease

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1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hair Disease

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Pathways for genes affiliated with Hair Disease

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Compounds for genes affiliated with Hair Disease

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44Novoseek, 24HMDB
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Compounds related to Hair Disease according to GeneCards/GeneDecks:

idCompoundScoreTop Affiliating Genes
1sodium azide449.4CP, COX5A
2carnitine449.4CP, COX5A
3copper histidine448.9CP, ATP7A, COX5A
4copper44 249.9COX5A, ATP7A, CP
5superoxide44 249.5CP, ATP7A, COX5A
6glutamate448.1COX5A, CNP, KRT86, CP

GO Terms for genes affiliated with Hair Disease

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16Gene Ontology
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Cellular components related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1keratin filamentGO:0450959.6KRT81, KRT86

Biological processes related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion transportGO:0068259.3CP, ATP7A

Molecular functions related to Hair Disease according to GeneCards/GeneDecks:

idNameGO IDScoreTop Affiliating Genes
1copper ion bindingGO:0055079.3CP, ATP7A

Products for genes affiliated with Hair Disease

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hair Disease

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet