MCID: HLL005
MIFTS: 23

Hallucinogen Dependence

Categories: Mental diseases

Aliases & Classifications for Hallucinogen Dependence

Summaries for Hallucinogen Dependence

Disease Ontology : 12 A drug dependence that involves the continued use of hallucinogenic drugs despite problems related to use of the substance.

MalaCards based summary : Hallucinogen Dependence is related to psychotic disorder and polysubstance abuse. An important gene associated with Hallucinogen Dependence is CNR1 (Cannabinoid Receptor 1), and among its related pathways/superpathways are Signaling by GPCR and Neuroscience. Related phenotypes are behavior/neurological and nervous system

Related Diseases for Hallucinogen Dependence

Diseases related to Hallucinogen Dependence via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 psychotic disorder 10.2
2 polysubstance abuse 10.0 CNR1 FAAH
3 autoimmune encephalitis 10.0 CNR1 FAAH
4 rohhad 9.9 HCRTR1 HCRTR2
5 post-traumatic stress disorder 9.8 CNR1 FAAH
6 sleep disorder 9.8 HCRTR1 HCRTR2
7 alcohol abuse 9.7 CNR1 FAAH
8 drug dependence 9.7 CNR1 PENK
9 cannabis dependence 9.5 CNR1 FAAH PENK

Graphical network of the top 20 diseases related to Hallucinogen Dependence:



Diseases related to Hallucinogen Dependence

Symptoms & Phenotypes for Hallucinogen Dependence

MGI Mouse Phenotypes related to Hallucinogen Dependence:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.43 CNR1 DAGLA FAAH HCRTR1 HCRTR2 PENK
2 nervous system MP:0003631 9.1 CNR1 DAGLA DAGLB FAAH HCRTR1 HCRTR2

Drugs & Therapeutics for Hallucinogen Dependence

Search Clinical Trials , NIH Clinical Center for Hallucinogen Dependence

Genetic Tests for Hallucinogen Dependence

Anatomical Context for Hallucinogen Dependence

Publications for Hallucinogen Dependence

Articles related to Hallucinogen Dependence:

# Title Authors Year
1
Evidence for a hallucinogen dependence syndrome developing soon after onset of hallucinogen use during adolescence. ( 17019896 )
2006

Variations for Hallucinogen Dependence

Expression for Hallucinogen Dependence

Search GEO for disease gene expression data for Hallucinogen Dependence.

Pathways for Hallucinogen Dependence

Pathways related to Hallucinogen Dependence according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
13.61 CNR1 DAGLA DAGLB HCRTR1 HCRTR2 PENK
2 12.11 CNR1 DAGLA DAGLB
3
Show member pathways
11.77 CNR1 DAGLA DAGLB FAAH
4 11.44 CNR1 DAGLA DAGLB
5
Show member pathways
10.87 DAGLA DAGLB
6 10.77 CNR1 FAAH
7 10.37 CNR1 DAGLA
8 10.32 CNR1 DAGLA DAGLB

GO Terms for Hallucinogen Dependence

Cellular components related to Hallucinogen Dependence according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 9.1 CNR1 DAGLA DAGLB HCRTR1 HCRTR2 PENK

Biological processes related to Hallucinogen Dependence according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 G-protein coupled receptor signaling pathway GO:0007186 9.85 CNR1 HCRTR1 HCRTR2 PENK
2 chemical synaptic transmission GO:0007268 9.58 HCRTR1 HCRTR2 PENK
3 lipid catabolic process GO:0016042 9.57 DAGLA DAGLB
4 response to ethanol GO:0045471 9.56 CNR1 PENK
5 neurogenesis GO:0022008 9.54 DAGLA DAGLB
6 sensory perception of pain GO:0019233 9.52 CNR1 PENK
7 cellular response to hormone stimulus GO:0032870 9.51 HCRTR1 HCRTR2
8 feeding behavior GO:0007631 9.49 HCRTR1 HCRTR2
9 response to nicotine GO:0035094 9.48 CNR1 PENK
10 regulation of cytosolic calcium ion concentration GO:0051480 9.46 HCRTR1 HCRTR2
11 response to morphine GO:0043278 9.43 CNR1 PENK
12 neuroblast proliferation GO:0007405 9.37 DAGLA DAGLB
13 neuropeptide signaling pathway GO:0007218 9.33 HCRTR1 HCRTR2 PENK
14 response to peptide GO:1901652 9.32 HCRTR1 HCRTR2
15 neurotransmitter biosynthetic process GO:0042136 9.26 DAGLA DAGLB
16 regulation of circadian sleep/wake cycle, sleep GO:0045187 8.96 HCRTR1 HCRTR2
17 arachidonic acid metabolic process GO:0019369 8.8 DAGLA DAGLB FAAH

Molecular functions related to Hallucinogen Dependence according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide binding GO:0042277 9.26 HCRTR1 HCRTR2
2 peptide hormone binding GO:0017046 9.16 HCRTR1 HCRTR2
3 orexin receptor activity GO:0016499 8.96 HCRTR1 HCRTR2
4 acylglycerol lipase activity GO:0047372 8.8 DAGLA DAGLB FAAH

Sources for Hallucinogen Dependence

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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