MCID: HLN001
MIFTS: 29

Halo Nevi malady

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Halo Nevi

About this section

Aliases & Descriptions for Halo Nevi:

Name: Halo Nevi 45
Leukoderma Acquisitum Centrifugum of Sutton 45
 
Halo Nevus 65

Classifications:



External Ids:

UMLS65 C0474824

Summaries for Halo Nevi

About this section
MalaCards based summary: Halo Nevi, also known as leukoderma acquisitum centrifugum of sutton, is related to hemophilia and aneurysm. An important gene associated with Halo Nevi is HLA-DRB1 (Major Histocompatibility Complex, Class II, DR Beta 1), and among its related pathways are Epstein-Barr virus infection and Toxoplasmosis. Affiliated tissues include skeletal muscle, heart and colon.

Related Diseases for Halo Nevi

About this section

Graphical network of the top 20 diseases related to Halo Nevi:



Diseases related to halo nevi

Symptoms for Halo Nevi

About this section

Drugs & Therapeutics for Halo Nevi

About this section

Interventional clinical trials:

Search ClinicalTrials, NIH Clinical Center for Halo Nevi

Genetic Tests for Halo Nevi

About this section

Anatomical Context for Halo Nevi

About this section

MalaCards organs/tissues related to Halo Nevi:

33
Skeletal muscle, Heart, Colon, Kidney, Lung, T cells, Testis

Animal Models for Halo Nevi or affiliated genes

About this section

MGI Mouse Phenotypes related to Halo Nevi:

38
idDescriptionMGI Source AccessionScoreTop Affiliating Genes

Publications for Halo Nevi

About this section

Articles related to Halo Nevi:

(show all 39)
idTitleAuthorsYear
1
Novel heterozygous C243Y A20/TNFAIP3 gene mutation is responsible for chronic inflammation in autosomal-dominant BehAset's disease. (27175295)
2016
2
Cardiac Complications in 38 Cases of Kawasaki Disease with Coronary Artery Aneurysm Diagnosed by Echocardiography. (26711003)
2016
3
Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells. (23269235)
2013
4
Altered dynamics of a lipid raft associated protein in a kidney model of Fabry disease. (24215843)
2013
5
A formulation for in situ lysis of mucin secreted in pseudomyxoma peritonei. (23843173)
2013
6
Chronic unremitting headache associated with Lyme disease-like illness. (23857618)
2013
7
Thin-section chest CT findings in systemic lupus erythematosus with antiphospholipid syndrome: a comparison with systemic lupus erythematosus without antiphospholipid syndrome. (21501937)
2012
8
Molecular convergence of hexosamine biosynthetic pathway and ER stress leading to insulin resistance in L6 skeletal muscle cells. (19370316)
2009
9
Imaging features of constrictive pericarditis: beyond pericardial thickening. (19433028)
2009
10
Recombinant vesicular stomatitis virus expressing influenza nucleoprotein induces CD8 T-cell responses that enhance antibody-mediated protection after lethal challenge with influenza virus. (19244472)
2009
11
Spondyloarthropathies: Targeted therapy for psoriatic arthritis. (19412187)
2009
12
Discovery and validation of biomarkers that respond to treatment with brivanib alaninate, a small-molecule VEGFR-2/FGFR-1 antagonist. (17638901)
2007
13
Two cases of alopecia areata responsive to fexofenadine. (18078416)
2007
14
The neurotrophic receptor TrkB: a drug target in anti-cancer therapy? (16568244)
2006
15
Importin 7 may be dispensable for human immunodeficiency virus type 1 and simian immunodeficiency virus infection of primary macrophages. (16103209)
2005
16
CKLFSF2 is highly expressed in testis and can be secreted into the seminiferous tubules. (15896670)
2005
17
Attenuated expression of DFFB is a hallmark of oligodendrogliomas with 1p-allelic loss. (16156899)
2005
18
Severe subacute GM2 gangliosidosis caused by an apparently silent HEXA mutation (V324V) that results in aberrant splicing and reduced HEXA mRNA. (15108204)
2004
19
A novel mutation in the chloride channel gene, CLCNKB, as a cause of Gitelman and Bartter syndromes. (12472765)
2003
20
The SAPHO syndrome--a report of 2 patients. (12440506)
2002
21
Magoh, a human homolog of Drosophila mago nashi protein, is a component of the splicing-dependent exon-exon junction complex. (11707413)
2001
22
Cyclooxygenase-2 in human perinatal lung. (10813584)
2000
23
Chemoprevention of colon cancer by specific cyclooxygenase-2 inhibitor, celecoxib, administered during different stages of carcinogenesis. (10667579)
2000
24
Signal transduction-mediated CYP1A1 induction by omeprazole in human HepG2 cells. (10445394)
1999
25
Mechanism of biological synergy between cellular Src and epidermal growth factor receptor. (9990038)
1999
26
Thiol-dependent metal-catalyzed oxidation of copper, zinc superoxide dismutase. (9748611)
1998
27
The biochemical marker dynamics of the maternal serum in different chromosomal disorders of the fetus]. (9879118)
1998
28
Idiopathic thrombocytopenic purpura and food allergy: a study on possible correlations]. (10335541)
1998
29
Effect of interleukin 12 on in vitro HIV type 1 replication depends on clinical stage. (8744576)
1996
30
Antibodies to phosphatidylethanolamine in antiphospholipid syndrome and systemic lupus erythematosus: their correlation with anticardiolipin antibodies and beta 2 glycoprotein-I plasma levels. (8025204)
1993
31
Regulation of locomotion and cell-cell contact area by the LFA-1 and ICAM-1 adhesion receptors. (1349320)
1992
32
Acute myelomonocytic leukemia with marrow eosinophilia showing 5q- and 16q22 mosaicism. (1551075)
1992
33
Difficulties in the diagnosis of congenital toxoplasmosis by cordocentesis. Case report. (1911595)
1991
34
Postpartum gentamicin dosing and endometritis. (2327459)
1990
35
Management of subaortic stenosis in the univentricular heart. (2730187)
1989
36
Tuberculosis presenting as retinal vasculitis. (3373471)
1988
37
Leiomyosarcoma in the mesentery presenting as a uterine fibroid. (7326631)
1981
38
Meningococcemia in two siblings; with special reference to gangrene as a complication in one case. (13371565)
1956
39
Massive nonfilarial genital elephantiasis; report of a unusual case. (18152295)
1949

Variations for Halo Nevi

About this section

Expression for genes affiliated with Halo Nevi

About this section
Search GEO for disease gene expression data for Halo Nevi.

Pathways for genes affiliated with Halo Nevi

About this section

Pathways related to Halo Nevi according to GeneCards Suite gene sharing:

(show all 18)
idSuper pathwaysScoreTop Affiliating Genes
19.0HLA-DRB1, HLA-DRB4
2
Show member pathways
9.0HLA-DRB1, HLA-DRB4
3
Show member pathways
9.0HLA-DRB1, HLA-DRB4
4
Show member pathways
9.0HLA-DRB1, HLA-DRB4
5
Show member pathways
9.0HLA-DRB1, HLA-DRB4
6
Show member pathways
9.0HLA-DRB1, HLA-DRB4
7
Show member pathways
9.0HLA-DRB1, HLA-DRB4
89.0HLA-DRB1, HLA-DRB4
99.0HLA-DRB1, HLA-DRB4
10
Show member pathways
9.0HLA-DRB1, HLA-DRB4
119.0HLA-DRB1, HLA-DRB4
129.0HLA-DRB1, HLA-DRB4
139.0HLA-DRB1, HLA-DRB4
149.0HLA-DRB1, HLA-DRB4
15
Show member pathways
9.0HLA-DRB1, HLA-DRB4
169.0HLA-DRB1, HLA-DRB4
179.0HLA-DRB1, HLA-DRB4
189.0HLA-DRB1, HLA-DRB4

GO Terms for genes affiliated with Halo Nevi

About this section

Cellular components related to Halo Nevi according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1ER to Golgi transport vesicle membraneGO:00125079.1HLA-DRB1, HLA-DRB4
2external side of plasma membraneGO:00098979.0HLA-DRB1, HLA-DRB4
3trans-Golgi network membraneGO:00325888.9HLA-DRB1, HLA-DRB4

Biological processes related to Halo Nevi according to GeneCards Suite gene sharing:

idNameGO IDScoreTop Affiliating Genes
1immunoglobulin production involved in immunoglobulin mediated immune responseGO:00023819.6HLA-DRB1, HLA-DRB4
2peptide antigen assembly with MHC class II protein complexGO:00025039.6HLA-DRB1, HLA-DRB4
3regulation of interleukin-10 secretionGO:20011799.6HLA-DRB1, HLA-DRB4
4T-helper 1 type immune responseGO:00420889.6HLA-DRB1, HLA-DRB4
5humoral immune response mediated by circulating immunoglobulinGO:00024559.4HLA-DRB1, HLA-DRB4
6immune responseGO:00069559.0HLA-DRB1, HLA-DRB4

Sources for Halo Nevi

About this section
2CDC
14ExPASy
15FDA
16FMA
24GTR
25HGMD
26HMDB
27ICD10
28ICD10 via Orphanet
29ICD9CM
30IUPHAR
31KEGG
34MedGen
36MeSH
37MESH via Orphanet
38MGI
41NCI
42NCIt
43NDF-RT
46NINDS
47Novoseek
49OMIM
50OMIM via Orphanet
54PubMed
55QIAGEN
60SNOMED-CT via Orphanet
64Tumor Gene Family of Databases
65UMLS
66UMLS via Orphanet