MCID: HND002
MIFTS: 50

Hand, Foot and Mouth Disease

Categories: Infectious diseases

Aliases & Classifications for Hand, Foot and Mouth Disease

Summaries for Hand, Foot and Mouth Disease

Disease Ontology : 12 A viral infectious disease that results_in infection located in skin, has material basis in Human coxsackievirus A16 or has material basis in Human enterovirus 71, which are transmitted_by contaminated fomites, and transmitted_by contact with nose and throat secretions, saliva, blister fluid and stool of infected persons. The infection has symptom fever, has symptom poor appetite, has symptom malaise, has symptom sore throat, has symptom painful sores in the mouth, and has symptom skin rash on the palms of the hands and soles of the feet.

MalaCards based summary : Hand, Foot and Mouth Disease, also known as vesicular stomatitis and exanthem, is related to herpangina and mouth disease, and has symptoms including fever, poor appetite and malaise. An important gene associated with Hand, Foot and Mouth Disease is SCARB2 (Scavenger Receptor Class B Member 2), and among its related pathways/superpathways are Allograft rejection and Th17 cell differentiation. The drugs Mannitol and Ribavirin have been mentioned in the context of this disorder. Affiliated tissues include skin, skin and tongue, and related phenotype is skeleton.

CDC : 3 Hand, foot, and mouth disease is a common viral illness that usually affects infants and children younger than 5 years old. However, it can sometimes occur in older children and adults. Typical symptoms of hand, foot, and mouth disease include fever, mouth sores, and a skin rash.

Wikipedia : 72 Hand, foot, and mouth disease (HFMD) is a common infection caused by a group of viruses. It typically... more...

Related Diseases for Hand, Foot and Mouth Disease

Diseases related to Hand, Foot and Mouth Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)
# Related Disease Score Top Affiliating Genes
1 herpangina 30.4 C4A CA10 SCARB2
2 mouth disease 30.2 HMGB1 IFNG IL10 IL17F IL6 SCARB2
3 graft-versus-host disease 30.2 IFNG IL10 IL6
4 meningitis 30.2 IFNG IL10 IL6
5 aseptic meningitis 30.2 IFNG IL10
6 nervous system disease 30.2 IFNG IL10 IL6
7 kawasaki disease 30.1 IL10 IL6 NPPB
8 eye lymphoma 10.5 IL10 IL6
9 acute transverse myelitis 10.5 IL10 IL6
10 hyperlucent lung 10.5 IFNG IL10
11 funisitis 10.4 IL10 IL6
12 sporotrichosis 10.4 IFNG IL10
13 baylisascariasis 10.4 IFNG IL10
14 b-cell growth factor 10.4 IFNG IL6
15 chronic graft versus host disease 10.4 IFNG IL10
16 clonorchiasis 10.4 IFNG IL10
17 pericardial tuberculosis 10.4 IFNG IL10
18 cardiogenic shock 10.4 IL6 NPPB
19 tuberculoid leprosy 10.4 IFNG IL10
20 orofacial granulomatosis 10.4 IFNG IL10
21 ascaris lumbricoides infection 10.4 IFNG IL6
22 buruli ulcer 10.4 IFNG IL10
23 listeriosis 10.4 IL10 IL6
24 microscopic colitis 10.4 IFNG IL6
25 chronic active epstein-barr virus infection 10.4 IFNG IL10
26 meconium aspiration syndrome 10.4 IFNG IL6
27 relapsing polychondritis 10.4 IFNG IL6
28 transverse myelitis 10.4 IL10 IL6
29 central nervous system vasculitis 10.4 IFNG IL6
30 poliomyelitis 10.4 IFNG IL10
31 fascioliasis 10.3 IFNG IL10
32 primary systemic mycosis 10.3 IFNG IL10
33 encephalitis 10.3
34 post-transplant lymphoproliferative disease 10.3 IL10 IL6
35 gaucher disease, type i 10.3 GBA SCARB2
36 peanut allergy 10.3 IFNG IL10
37 campylobacteriosis 10.3 IFNG VDR
38 radiculopathy 10.3 IL10 IL6
39 ischemic heart disease 10.3 IL6 NPPB
40 coccidiosis 10.3 IFNG IL10
41 immune suppression 10.3 IFNG IL10 IL6
42 multicentric castleman disease 10.3 IFNG IL10 IL6
43 intermediate uveitis 10.3 IFNG IL10 IL6
44 eales disease 10.3 IFNG IL10 IL6
45 hemorrhagic fever 10.3 IFNG IL10 IL6
46 hematopoietic stem cell transplantation 10.3 IFNG IL10 IL6
47 mucinoses 10.3 C4A IFNG
48 cytomegalovirus infection 10.3 IFNG IL10 IL6
49 plasmodium vivax malaria 10.3 IFNG IL10 IL6
50 paracoccidioidomycosis 10.3 IFNG IL10 IL6

Graphical network of the top 20 diseases related to Hand, Foot and Mouth Disease:



Diseases related to Hand, Foot and Mouth Disease

Symptoms & Phenotypes for Hand, Foot and Mouth Disease

Symptoms:

12
  • fever
  • poor appetite
  • malaise
  • sore throat
  • painful sores in the mouth
  • skin rash on the palms of the h

MGI Mouse Phenotypes related to Hand, Foot and Mouth Disease:

43
# Description MGI Source Accession Score Top Affiliating Genes
1 skeleton MP:0005390 9.17 OAS1 VDR GBA IFNG IL10 IL17F

Drugs & Therapeutics for Hand, Foot and Mouth Disease

Drugs for Hand, Foot and Mouth Disease (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 64)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Mannitol Approved, Investigational Phase 4 69-65-8 6251 453
2
Ribavirin Approved Phase 4 36791-04-5 37542
3 Antibodies Phase 4
4 Immunoglobulins Phase 4
5 Vaccines Phase 4,Phase 3,Phase 2,Phase 1
6 Anti-Infective Agents Phase 4
7 Antimetabolites Phase 4
8 Antiviral Agents Phase 4
9 Antibodies, Blocking Phase 4
10
Ibuprofen Approved Phase 2 15687-27-1 3672
11
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 2 7487-88-9 24083
12
Acetaminophen Approved Phase 2 103-90-2 1983
13
Sucralfate Approved Phase 2 54182-58-0 0
14
Vitamin A Approved, Nutraceutical, Vet_approved Phase 2 68-26-8, 11103-57-4 445354
15 Pharmaceutical Solutions Phase 2
16 Analgesics Phase 2
17 Anesthetics Phase 2
18 Anti-Arrhythmia Agents Phase 2
19 Anticonvulsants Phase 2
20 calcium channel blockers Phase 2
21 Calcium, Dietary Phase 2
22 Central Nervous System Depressants Phase 2
23 Peripheral Nervous System Agents Phase 2
24 Retinol palmitate Phase 2
25 Tocolytic Agents Phase 2
26 Antacids Phase 2,Phase 1
27 Anti-Inflammatory Agents Phase 2
28 Anti-Ulcer Agents Phase 2,Phase 1
29 Gastrointestinal Agents Phase 2,Phase 1
30 Analgesics, Non-Narcotic Phase 2
31 Anti-Inflammatory Agents, Non-Steroidal Phase 2
32 Antipyretics Phase 2
33 Antirheumatic Agents Phase 2
34 Cyclooxygenase Inhibitors Phase 2
35 retinol Nutraceutical Phase 2
36
Aluminum hydroxide Approved, Investigational Phase 1 21645-51-2
37 Adjuvants, Immunologic Phase 1
38
Methylprednisolone Approved, Vet_approved 83-43-2 6741
39
Prednisolone Approved, Vet_approved 50-24-8 5755
40
Vitamin C Approved, Nutraceutical 50-81-7 54670067 5785
41 Grape Approved, Nutraceutical
42 Anti-Bacterial Agents
43 Antibiotics, Antitubercular
44 Vitamins
45 Vitamin B Complex
46 Antiemetics
47 Antineoplastic Agents, Hormonal
48 Autonomic Agents
49 diuretics
50 glucocorticoids

Interventional clinical trials:

(show all 33)

# Name Status NCT ID Phase Drugs
1 Effect of Xiaoer Jiebiao Oral Liquid on Hand-foot-mouth Disease Recruiting NCT02328651 Phase 4 Ribavirin plus Xiao'er jiebiao oral liquid;Ribavirin
2 Phase IV Clinical Trial, Immunogenicity and Safety of EV71 Vaccine Recruiting NCT03278132 Phase 4
3 Safety and Immunogenicity of Concomitant Administration of EV71 Vaccine With EPI Vaccines Recruiting NCT03274102 Phase 4
4 The Phase IVb of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Children Active, not recruiting NCT03001986 Phase 4
5 The Phase IVc of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell) Active, not recruiting NCT03240744 Phase 4
6 The Phase IVa of Inactivated Enterovirus 71 Vaccine (Human Diploid Cell, KMB-17) Active, not recruiting NCT02999828 Phase 4
7 The Phase IVd of Inactivated Enterovirus 71 Vaccine Enrolling by invitation NCT03296410 Phase 4
8 Safety, Three Batches Consistency and Immunity Duration of the Post-marketing Inactivated Enterovirus Type 71 (EV71) Vaccine in Children Aged 6-71 Months Not yet recruiting NCT02889497 Phase 4
9 An Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine Completed NCT01507857 Phase 3
10 Immunogenicity and Safety of Three Consecutive Lots of a New Inactivated Enterovirus Type 71 (EV71) Vaccine Completed NCT01636245 Phase 3
11 A Clinical Trial to Assess the Efficacy and Safety of an Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children Aged 6-35 Months Completed NCT01508247 Phase 3
12 A Protected Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants and Children Completed NCT01569581 Phase 3
13 Magnesium Sulphate for Severe Hand, Foot and Mouth Disease in Vietnam Completed NCT01940250 Phase 2 Magnesium Sulphate;Sterile water
14 A Phase II, Safety and Efficacy Study of Inactivated EV 71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Infants Completed NCT01512706 Phase 2
15 A Study to Evaluate the Safety and Immunogenicity of EV71 Vaccine in Pediatric Subjects Aged 3 to 6 Years and 6 to 35 Months Old Completed NCT02777411 Phase 2
16 A Study to Evaluate the Immunogenicity and Safety of EV71 Vaccine in Pediatric Subjects Aged 3 to 6 Years and 2 to 35 Months Old Active, not recruiting NCT03268083 Phase 2
17 Sucralfate to Improve Oral Intake in Children With Infectious Oral Ulcers: a Randomized, Double-blind, Placebo-Controlled Trial Enrolling by invitation NCT03241030 Phase 2 Sucralfate;Acetaminophen;Ibuprofen
18 Safety and Immunogenicity Study of an Inactivated Vaccine Against Hand, Foot and Mouth Disease Caused by Enterovirus 71 Completed NCT01376479 Phase 1
19 A Safety Study of Inactivated EV71 Vaccine (Human Diploid Cell, KMB-17) in Chinese Adults, Children and Infants Completed NCT01391494 Phase 1
20 A Clinical Trial for Inactivated Vaccine(Vero Cell) Against EV71 in Chinese Healthy Young Adults and Children Completed NCT01267903 Phase 1
21 Safety of an Inactivated Enterovirus Type 71 Vaccines in Healthy Children Completed NCT01273246 Phase 1
22 A Clinical Trial for Inactivated Vaccine (Vero Cell) Against EV71 in Chinese Children and Infants Completed NCT01313715 Phase 1
23 A Multi-Center Clinical Trial To Evaluate Chinese Herbal Medicines in the Treatment of Severe Hand-foot-mouth Disease Unknown status NCT01145664 Herbal concentrate-granules plus western therapy;Reduning Injection plus western therapy;Western therapy
24 A Clinical Trial To Evaluate Reduning Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease Unknown status NCT01175915
25 A Clinical Trial to Evaluate the Effectiveness and Safety of Xiyanping Injection in the Treatment of Mild Type of Hand, Foot, and Mouth Disease Unknown status NCT01182025 Xiyanping Injection;Xiyanping Injection with western medicine
26 Neurodevelopment Outcomes Following Severe Hand Foot and Mouth Disease in Vietnam Completed NCT02066714
27 A Follow-up Study for a Phase III, Efficacy Trial in Inactivated Enterovirus Type 71 (EV71) Vaccine Completed NCT02001233
28 Chinese Medicinal Treatment on Mild Hand, Foot, and Mouth Disease: Multicenter, Prospective, Randomized Double-blind, Placebo-controlled Study Completed NCT01769794 Western therapy;JET;Placebo(for JET)
29 A Clinical Trial to Evaluate the Effectiveness and Safety of Chinese Medicine in the Treatment of Mild Type of Hand, Foot, and Mouth Disease Completed NCT01182532 TCM Syndrome Differentiation and Treatment
30 Five-year Immune Persistence Study of Inactivated Enterovirus Type 71 (EV71) Vaccine Completed NCT03281174
31 Study on Dynamic Changes of the Maternal Anti-EV71 and Anti-CVA16 Antibody Levels in Infants and Young Children Completed NCT01255124
32 Do Traditional or Flavored Tongue Depressors Make for Easier Posterior Oropharynx Exams in Pediatric Patients Completed NCT03095183
33 Effectiveness and Safety of Chinese Medicine to Treat Hand, Foot, and Mouth Disease Completed NCT01554930 Western therapy (mannitol, methylprednisolone, immunoglobulin, febrifuge);Xiyanping injection plus western therapy

Search NIH Clinical Center for Hand, Foot and Mouth Disease

Cochrane evidence based reviews: hand, foot and mouth disease

Genetic Tests for Hand, Foot and Mouth Disease

Anatomical Context for Hand, Foot and Mouth Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Hand, Foot and Mouth Disease:

18
Skin

MalaCards organs/tissues related to Hand, Foot and Mouth Disease:

38
Skin, Tongue, Testes, Brain

Publications for Hand, Foot and Mouth Disease

Articles related to Hand, Foot and Mouth Disease:

(show top 50) (show all 381)
# Title Authors Year
1
Impact of meteorological factors on the incidence of childhood hand, foot, and mouth disease (HFMD) analyzed by DLNMs-based time series approach. ( 29391070 )
2018
2
Hand, foot and mouth disease in an adult. ( 29372548 )
2018
3
Quantifying the influence of temperature on hand, foot and mouth disease incidence in Wuhan, Central China. ( 29386630 )
2018
4
An evaluation of Chloroquine as a broad-acting antiviral against Hand, Foot and Mouth Disease. ( 29175128 )
2018
5
Epidemiological Characteristics and Spatial-Temporal Distribution of Hand, Foot, and Mouth Disease in Chongqing, China, 2009-2016. ( 29401726 )
2018
6
Hand, foot and mouth disease: current knowledge on clinical manifestations, epidemiology, aetiology and prevention. ( 29411190 )
2018
7
Different responses of weather factors on hand, foot and mouth disease in three different climate areas of Gansu, China. ( 29310596 )
2018
8
Parental perspectives on hand, foot, and mouth disease among children in Hong Kong: a longitudinal study. ( 29386079 )
2018
9
Full-Genome Sequence of an Enterovirus 71 Strain Isolated from a Throat Swab from a Child with Severe Hand-Foot-and-Mouth Disease in Changzhou, China, in 2017. ( 29371346 )
2018
10
Epidemiological and serological surveillance of hand-foot-and-mouth disease in Shanghai, China, 2012-2016. ( 29362406 )
2018
11
Vitamin D receptor protects glioblastoma A172A cells against Coxsackievirus A16 infection induced cell death in the pathogenesis of hand, foot, and mouth disease. ( 28943436 )
2017
12
Genetic characterization of enterovirus strains identified in Hand, Foot and Mouth Disease (HFMD): Emergence of B1c, C1 subgenotypes, E2 sublineage of CVA16, EV71 and CVA6 strains in India. ( 28577914 )
2017
13
Epidemiology of hand, foot and mouth disease in China, 2008 to 2015 prior to the introduction of EV-A71 vaccine. ( 29258646 )
2017
14
A mild phenotype of hand, foot and mouth disease caused by Coxsackievirus A6. ( 28681725 )
2017
15
Synonymous codon usage analysis of hand, foot and mouth disease viruses: A comparative study on coxsackievirus A6, A10, A16, and enterovirus 71 from 2008 to 2015. ( 28602802 )
2017
16
Derivation and Validation of a Mortality Risk Score for Severe Hand, Foot and Mouth Disease in China. ( 28611398 )
2017
17
A sudden paediatric death due to hand, foot and mouth disease: the importance of vigilance. ( 28866699 )
2017
18
Simultaneous occurrence of hand foot and mouth disease and pityriasis rosea. ( 29144097 )
2017
19
Severe hand, foot and mouth disease associated with Coxsackievirus A10 infections in Xiamen, China in 2015. ( 28577423 )
2017
20
Acute pancreatitis in hand, foot and mouth disease caused by Coxsackievirus A16: case report. ( 29158768 )
2017
21
Spatio-temporal clustering analysis and its determinants of hand, foot and mouth disease in Hunan, China, 2009-2015. ( 28946852 )
2017
22
A Retrospective Study of 331 Deaths in Children with Severe Hand, Foot and Mouth Disease in Guangxi, China. ( 29242411 )
2017
23
The exposure-response relationship between temperature and childhood hand, foot and mouth disease: A multicity study from mainland China. ( 28069250 )
2017
24
Antiviral activity of acid beta-glucosidase 1 on enterovirus 71, a causative agent of hand, foot and mouth disease. ( 28141506 )
2017
25
Immunopathogenesis and Virus-Host Interactions of Enterovirus 71 in Patients with Hand, Foot and Mouth Disease. ( 29238324 )
2017
26
Hand, Foot and Mouth Disease in West Bengal, India: A Preliminary Report on Clinicovirological Trend over 3 Successive Years (2013-2015). ( 28979010 )
2017
27
Clinical characteristics of hand, foot and mouth disease in Daklak Province, Vietnam and associated factors of severe cases. ( 29291236 )
2017
28
Epidemiological and genetic analysis concerning the non-enterovirus 71 and non-coxsackievirus A16 causative agents related to hand, foot and mouth disease in Anyang city, Henan Province, China, from 2011 to 2015. ( 28480969 )
2017
29
Tailoring Diagnostic Studies in Hand, Foot, and Mouth Disease: Utility of PCR testing of Lesional Skin. ( 28940373 )
2017
30
Case report: Features of hand, foot and mouth disease in neonates. ( 29049234 )
2017
31
Economic costs and health-related quality of life for hand, foot and mouth disease (HFMD) patients in China. ( 28934232 )
2017
32
Temporal and spatial analysis of hand, foot, and mouth disease in relation to climate factors: A study in the Mekong Delta region, Vietnam. ( 28063653 )
2017
33
Clinical Significance and Prognostic Effect of Serum 25-hydroxyvitamin D Concentrations in Critical and Severe Hand, Foot and Mouth Disease. ( 28489032 )
2017
34
A Case-control Study on Risk Factors for Severe Hand, Foot and Mouth Disease. ( 28084311 )
2017
35
Clinical significance of inflammatory cytokine and chemokine expression in hand, foot and mouth disease. ( 28447721 )
2017
36
Estimating the incubation period of hand, foot and mouth disease for children in different age groups. ( 29184105 )
2017
37
Spatiotemporal risk mapping of hand, foot and mouth disease and its association with meteorological variables in children under 5 years. ( 28891456 )
2017
38
Hand, foot, and mouth disease in mainland China before it was listed as category C disease in May, 2008. ( 28948918 )
2017
39
Alteration of serum high-mobility group protein 1 (HMGB1) levels in children with enterovirus 71-induced hand, foot, and mouth disease. ( 28445307 )
2017
40
Clinical features for 89 deaths of hand, foot and mouth disease in Guangxi, China, 2014. ( 28882666 )
2017
41
Serum interleukin-6 levels as an indicator of aseptic meningitis among children with enterovirus 71-induced hand, foot and mouth disease. ( 29231065 )
2017
42
Monitoring hand, foot and mouth disease by combining search engine query data and meteorological factors. ( 28898935 )
2017
43
Epidemiology of 45,616 suspect cases of Hand, Foot and Mouth Disease in Chongqing, China, 2011-2015. ( 28422128 )
2017
44
Atypical hand, foot and mouth disease due to Coxsackievirus A6 in a traveler returning from Indonesia to Italy. ( 28498983 )
2017
45
Proximal onycholysis as a complication of hand, foot, and mouth disease. ( 28083877 )
2017
46
Clinical analysis of 59 children with hand foot and mouth diseases due to enterovirus EV71 and concomitant viral encephalitis. ( 29165766 )
2017
47
Morphological characteristics of fatal pediatric hand, foot and mouth disease: A clinicopathological study with related receptors of EV71. ( 28756983 )
2017
48
The impact of hand, foot and mouth disease control policies in Singapore: A qualitative analysis of public perceptions. ( 28533530 )
2017
49
Therapeutic efficacy of phentolamine in the management of severe hand, foot and mouth disease combined with pulmonary edema. ( 28413485 )
2017
50
Hand, foot and mouth disease in adult patients. ( 28776773 )
2017

Variations for Hand, Foot and Mouth Disease

Expression for Hand, Foot and Mouth Disease

Search GEO for disease gene expression data for Hand, Foot and Mouth Disease.

Pathways for Hand, Foot and Mouth Disease

Pathways related to Hand, Foot and Mouth Disease according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.63 C4A IFNG IL10 IL6
2
Show member pathways
12.36 IFNG IL10 IL17F IL6
3
Show member pathways
12.34 IFNG IL10 IL17F IL6
4
Show member pathways
12.14 IFNG IL10 IL6
5 11.96 C4A IL10 IL6
6 11.88 IFNG IL10 IL6 VDR
7 11.79 IFNG IL10 IL6
8 11.77 IL10 IL17F IL6
9
Show member pathways
11.69 IFNG IL10 IL6
10 11.64 IFNG IL10 IL6
11 11.64 IFNG IL10 IL6
12
Show member pathways
11.59 IFNG IL17F IL6
13 11.49 C4A IL10 IL6
14 11.45 IFNG IL10 IL6
15 11.23 IFNG IL10 IL6
16
Show member pathways
11.13 IFNG IL10 IL6 OAS1
17 11.1 IFNG IL6
18 11.09 IFNG IL6 VDR
19 10.99 IFNG IL10
20 10.88 IFNG IL10 IL6
21 10.61 IFNG IL10 IL6

GO Terms for Hand, Foot and Mouth Disease

Cellular components related to Hand, Foot and Mouth Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.56 C4A HMGB1 IFNG IL10 IL17F IL6
2 extracellular space GO:0005615 9.23 C4A GBA HMGB1 IFNG IL10 IL17F

Biological processes related to Hand, Foot and Mouth Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of transcription by RNA polymerase II GO:0045944 9.88 HMGB1 IL10 IL17F IL6 VDR
2 immune response GO:0006955 9.71 IFNG IL10 IL6 OAS1
3 defense response to virus GO:0051607 9.63 IFNG IL6 OAS1
4 negative regulation of interferon-gamma production GO:0032689 9.43 HMGB1 IL10
5 negative regulation of interleukin-6 production GO:0032715 9.37 GBA IL10
6 inflammatory response GO:0006954 9.35 C4A HMGB1 IL10 IL17F IL6
7 neuron projection development GO:0031175 9.33 GBA HMGB1 IL6
8 positive regulation of interleukin-12 production GO:0032735 9.32 HMGB1 IFNG
9 positive regulation of interleukin-6 secretion GO:2000778 9.26 HMGB1 IL17F
10 regulation of receptor activity GO:0010469 9.1 HMGB1 IFNG IL10 IL17F IL6 NPPB

Molecular functions related to Hand, Foot and Mouth Disease according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytokine activity GO:0005125 9.02 HMGB1 IFNG IL10 IL17F IL6

Sources for Hand, Foot and Mouth Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
16 ExPASy
18 FMA
27 GO
28 GTR
29 HGMD
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 MedGen
41 MeSH
42 MESH via Orphanet
43 MGI
45 NCI
46 NCIt
47 NDF-RT
50 NINDS
51 Novoseek
53 OMIM
54 OMIM via Orphanet
58 PubMed
60 QIAGEN
65 SNOMED-CT via HPO
66 SNOMED-CT via Orphanet
67 TGDB
68 Tocris
69 UMLS
70 UMLS via Orphanet
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