HCL-V
MCID: HCL001
MIFTS: 21

Hcl-V (HCL-V) malady

Blood diseases, Cancer diseases categories

Summaries for Hcl-V

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Sources:
32MalaCards
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MalaCards: Hcl-V, also known as hairy cell leukemia variant, is related to polycythemia vera and polycythemia. An important gene associated with Hcl-V is IGHV4-34 (immunoglobulin heavy variable 4-34).

Aliases & Classifications for Hcl-V

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Sources:
8Disease Ontology, 48Orphanet, 60UMLS, 39NCIt, 56SNOMED-CT, 57SNOMED-CT via Orphanet, 26ICD10 via Orphanet
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Classifications:

Malacards categories (disease lists): (See all malacards categories)
Global: Cancer diseases
Anatomical: Blood diseases


Characteristics (Orphanet epidemiological data):

48
hairy cell leukemia variant:
Inheritance: Multigenic/multifactorial; Age of onset: Adulthood; Age of death: Adult


Aliases & Descriptions:

hcl-v 8 48
hairy cell leukemia variant 8 48 60
prolymphocytic variant of hairy cell leukemia 48
leukemic reticuloendotheliosis variant 48
prolymphocytic variant of hcl 48
hairy cell leukaemia variant 8


External Ids:

Disease Ontology8 DOID:713
NCIt39 C7401
SNOMED-CT56 54087003, 277568007
SNOMED-CT via Orphanet57 277568007
ICD10 via Orphanet26 C91.4

Related Diseases for Hcl-V

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Sources:
17GeneCards, 18GeneDecks
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Diseases related to Hcl-V via text searches within MalaCards or GeneCards/GeneDecks gene sharing:

idRelated DiseaseScoreTop Affiliating Genes
1polycythemia vera10.5
2polycythemia10.5
3prolymphocytic leukemia10.4
4refractory hairy cell leukemia10.2
5prostate lymphoma10.2
6prostatitis10.2

Graphical network of diseases related to Hcl-V:



Diseases related to hcl-v

Clinical Features for Hcl-V

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Drugs & Therapeutics for Hcl-V

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Sources:
5CenterWatch, 41NIH Clinical Center, 6ClinicalTrials
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Approved drugs:

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Drug clinical trials:

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Search CenterWatch for Hcl-V

Genetic Tests for Hcl-V

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Anatomical Context for Hcl-V

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Animal Models for Hcl-V or affiliated genes

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Publications for Hcl-V

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Sources:
50PubMed
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Articles related to Hcl-V:

idTitleAuthorsYear
1
Efficient vibrational and translational excitations of a solid metal surface: State-to-state time-of-flight measurements of HCl(v=2,J=1) scattering from Au(111). (19063576)
2008
2
Optical control of ground-state atomic orbital alignment: Cl(2P3/2) atoms from HCl(v=2,J=1) photodissociation. (17935395)
2007
3
Complete remission of hairy cell leukemia variant (HCL-v) complicated by red cell aplasia post treatment with rituximab. (16266917)
2005
4
Proliferative Hairy Cell Leukaemia (HCL-v) Resistant to Alpha-Interferon: Clinical, Diagnostic and In-Vitro Cellular Characteristics. (20394559)
1990

Genetic Variations for Hcl-V

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Expression for genes affiliated with Hcl-V

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Sources:
1BioGPS, 15Gene Expression Omnibus DataSets
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Expression patterns in normal tissues for genes affiliated with Hcl-V

Search GEO for disease gene expression data for Hcl-V.

Pathways for genes affiliated with Hcl-V

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Compounds for genes affiliated with Hcl-V

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GO Terms for genes affiliated with Hcl-V

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Products for genes affiliated with Hcl-V

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  • Antibodies
  • Proteins
  • Lysates
  • Antibodies

Sources for Hcl-V

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3CDC
13ExPASy
14FMA
22GTR
23HGMD
24HMDB
25ICD10
26ICD10 via Orphanet
27ICD9CM
28IUPHAR
29KEGG
34MeSH
35MESH via Orphanet
36MGI
39NCIt
40NDF-RT
43NINDS
44Novoseek
46OMIM
47OMIM via Orphanet
50PubMed
51QIAGEN
57SNOMED-CT via Orphanet
60UMLS
61UMLS via Orphanet